ライフサイエンスコーパス: sac

1 lack a gut (Porifera and Placozoa) or have a sac-like gut (Ctenophora and Cnidaria) and that a throug

2 od vessel, which allows blood to flow into a sac or a ballooned section.

3 The perception that ctenophores possess a sac-like blind gut with only one major opening remains a

4 The means of ILT and AAA sac ratios were 0.59 +/- 0.17 and 0.52 +/- 1.8 in growin

5 ILT and AAA sac volume ratio was calculated.

6 .59 +/- 0.17 and 0.52 +/- 1.8 in growing AAA sac and in stable or shrinking AAA sac groups, respectiv

7 owing AAA sac and in stable or shrinking AAA sac groups, respectively (p = 0.308).

8 mited growth conditions, sulfur acclimation (sac) mutants, which are more severely defective for accl

9 been previously reported, comprising an air sac-driven respiratory system with the potential for a b

10 The wing disc orchestrates dorsal air sac development by producing decapentaplegic and fibrobl

11 Drosophila dorsal air sac development depends on Decapentaplegic (Dpp) and Fib

12 napses for development of the Drosophila air sac primordium (ASP).

13 In air sac infection with MGAS2221, levels of neutrophils and m

14 : a dense, thick and downturned rostrum; air sac fossae; cranial asymmetry; and exceptionally broad m

15 5 Becn1Epi-KO lungs had reduced terminal air sac formation and vascularization and delayed distal epi

16 disc and transported by cytonemes to the air sac primordium (ASP).

17 ific cytonemes in order to signal to the air sac primordium (ASP).

18 hat produces Hh and is near the tracheal air sac primordium (ASP) and myoblasts.

19 at mimics the lung microenvironment with air sac-like structures and production of lung surfactant pr

20 o a densely packed honeycomb of alveolar air sacs that mediate gas exchange.

21 The flight muscles, dorsal air sacs, wing blades, and thoracic cuticle of the Drosophil

22 induced acoustic resonances in the nasal air sacs, recorded by biologging tags.

23 mbined with the extensive development of air sacs, suggests that Archaeopteryx was capable of flappin

24 ) at the respiratory epithelia (tracheal air sacs) of the thorax and head.

25 d, respectively, mimic or attenuate alveolar sac-like phenotypes in a co-culture model.

26 y GORAB as a regulator of embryonic alveolar sac formation as genetically disrupting the Gorab gene i

27 chyme fibroblasts, and suggest that alveolar sac formation resembles a patterning event that is orche

28 Embryonic development of the alveolar sac of the lung is dependent upon multiple signaling pat

29 embryogenic events centered around amniotic sac development.

30 Development of the asymmetric amniotic sac-with the embryonic disc and amniotic ectoderm occupy

31 onic development, it is unclear how amniotic sac formation is regulated.

32 e early embryogenic events of human amniotic sac development.

33 st pattern that resembles the human amniotic sac.

34 model, termed the post-implantation amniotic sac embryoid (PASE), that recapitulates multiple post-im

35 model, termed the post-implantation amniotic sac embryoid, to recapitulate early embryogenic events o

36 ial to embryogenesis and pregnancy, amniotic sac development in humans remains poorly understood.

37 r sFlt-1 were administered into the amniotic sac of pregnant rats at Embryonic Day 20 to simulate ant

38 rotic response is induced after the amniotic sac puncture.

39 UC 0.857, 95% CI: 0.755-0.928, p<0.0001) and sac-to-neck ratio (AUC 0.817, 95% CI: 0.708-0.898, p<0.0

40 Aneurysm neck diameter and sac-to-neck ratio are independently related to the resid

41 ignificant endoleak, defined as endoleak and sac diameter increase of 0.5 cm or greater.

42 ed to assess the value of abdominal aneurysm sac volume measurement for detecting expansions and the

43 r and volume of an abdominal aortic aneurysm sac can be used for temporal monitoring after endovascul

44 ine; volume of the abdominal aortic aneurysm sac; and volume from the lowest renal artery to the aort

45 The excluded aneurysm sac shrank with patent visceral branches and there was a

46 The strongest indicators for aneurysm sac enlargement are complex IMA-LA type II endoleak and

47 showed the strongest indicators for aneurysm sac enlargement were complex IMA-LA type II endoleak (od

48 r than 2.2 mm were at high risk for aneurysm sac enlargement.

49 Changes of postoperative maximum aneurysm sac diameter and AAA volume were calculated.

50 urement is an accurate indicator of aneurysm sac enlargement.

51 as mainly attributable to secondary aneurysm sac rupture (13 deaths [7%] in EVAR vs two [1%] in open

52 ree of the 56 patients (41%) showed aneurysm sac enlargement during follow-up (mean follow-up, 3.0 ye

53 largest cross-sectional area of the aneurysm sac was measured using a curved multiplanar reconstructi

54 rigin of the IMA in relation to the aneurysm sac, diameter of the IMA, the cross-sectional area of th

55 can divert blood flow away from the aneurysm sac.

56 atent aortic side branches from the aneurysm sac.

57 aluminal thrombus (ILT) volume with aneurysm sac growth following EVAR.

58 aortic wall within the expanding aneurysmal sac is present in > 90% of cases.

59 supports the coil mass inside the aneurysmal sac, and furthermore, has an effect on local hemodynamic

60 000 IU) was injected inside the aneurysmatic sac with its complete occlusion.

61 Avian ceca, a pair of blind sacs arising from the junction of the ileum and colon, a

62 adhesive matrices placed in the conjunctival sac can enhance drug delivery by increasing precorneal r

63 The emerging 'cul-de-sac hypothesis' predicts that reptilian viviparity ('liv

64 50 mul of sterile saline to the lower cul-de-sac of each eye and using capillary action microcaps to

65 , rebounding off the leaflet into the cul-de-sac, was noted in 82% of the obstructed HCM, 9% of nonob

66 ons and thus leads to an evolutionary cul-de-sac.

67 sults, but rather than being climatic cul-de-sacs, many mountain streams appear poised to be redoubts

68 amic aspect of the myodural bridges as dural sac stabilizers.

69 l bridges are thought to stabilize the dural sac during head and neck movements and promote cerebrosp

70 Genotyping of amniotic fluid from each sac showed that the twins were maternally identical but

71 uvenile instars and is not involved with egg sac construction.

72 produce silk used in the construction of egg sacs.

73 I cell is already transitioning to an embryo sac program prior to mitotic division.

74 n, namely in pollen tube guidance and embryo sac fertilization, pathogen defense, and responses to ab

75 most similar to the early aposporous embryo sac transcriptome when comparing known functional annota

76 llen with two sex cells in the female embryo sac.

77 ng ROS localization and important for embryo sac patterning.

78 e guidance to the female gametophyte (embryo sac) and its rupture to release sperm cells.

79 repulsion of multiple pollen tubes in embryo sac (IV2).

80 n a split gynoecium and no observable embryo sac.

81 stically established in the syncytial embryo sac by spatially restricted CKI1 expression, followed by

82 iosperms, double fertilization of the embryo sac initiates the development of the embryo and the endo

83 ing pollen tubes communicate with the embryo sac.

84 essful delivery of sperm cells to the embryo sac.

85 pment, including nonviable pollen and embryo sacs with unfused polar nuclei.

86 ies (ROS) accumulation in anthers and embryo sacs, as evidenced by nitroblue tetrazolium staining.

87 pomeiosis, the formation of unreduced embryo sacs derived from nucellar cells of the ovary and, by pa

88 shown to be important for pollen and embryo-sac development.

89 tic cavity, formation of a bipolar embryonic sac, and specification of primordial germ cells and gast

90 tic cavity, formation of a bipolar embryonic sac, and specification of primordial germ cells and prim

91 stoperative complications, type II endoleak, sac expansion, and additional interventions after EVAR.

92 between strain values and type of endoleak, sac pressure, endoleak size, and aneurysm size.

93 Here, we show that the mouse endolymphatic sac absorbs fluid in an SLC26A4-dependent fashion.

94 ession in the developing mouse endolymphatic sac is required for acquisition of normal inner ear stru

95 e and sympathetic paraganglia, endolymphatic sac, epididymis, and broad ligament.

96 ciated with enlargement of the endolymphatic sac (EES).

97 epithelium, a precursor of the endolymphatic sac (ES) and duct (ED), which mediate endolymph homeosta

98 The endolymphatic sac (ES) is a cystic organ that is a part of the inner e

99 analysis of pre- and postnatal endolymphatic sacs demonstrates two types of differentiated cells.

100 Enlarged sac-like lymphatics were abundant near major airways, pu

101 transepithelial transport using the everted sac method.

102 ain fatty acids in basal side of the everted sac.

103 Alveoli are gas-exchange sacs lined by squamous alveolar type (AT) 1 cells and cu

104 (ER), an interconnected network of flattened sacs or tubes.

105 pression was detected in the dental follicle/sac and dental papilla mesenchyme of developing teeth an

106 ed at 2.8 mm for neck diameter, and 1.73 for sac-to-neck ratio.

107 EP of less than 0.5 mL for showing no future sac volume enlargement were 33% (19 of 57), 100% (56 of

108 res are empty uterus and cervix, gestational sac in the anterior part of lower uterine segment with a

109 rospectively validate the use of gestational sac (GS), yolk sac (YS) diameter, crown-rump length (CRL

110 ere there is implantation of the gestational sac onto the anterior wall of the uterus at the site of

111 soprostol group did not pass the gestational sac spontaneously within 7 days versus 82 (24%) of 348 w

112 ailure to spontaneously pass the gestational sac within 7 days after random assignment.

113 of improper implantation of the gestational sac.

114 livery in a female with a viable gestational sac in the lower uterine segment and elevated B-Hcg leve

115 bsorption was analyzed using the everted gut sac experiment.

116 tous intestinal loop in a 70-mm-long hernial sac, with no circulation detected.

117 the exploration, the content of the hernial sac was found to be the fundus of the significantly ptot

118 in cystic structure was found in the hernial sac, and several small abnormal masses were palpated the

119 ent (w/w) was 17.93% (nectar), 47.03% (honey sac) and 79.63% (honey).

120 the chemical composition of individual honey sac contents with the most intensive and complex absorpt

121 mandarin (Citrus unshiu Marc.) nectar, honey sac content and honey were analyzed by FTIR-ATR spectros

122 conversion takes place directly in the honey sac; the average sugar content (w/w) was 17.93% (nectar)

123 ental design; ex vivo rat everted intestinal sac model, cellular lipid uptake and the bioactivity in

124 A non-everted rat intestinal sac model was used in conjunction to assess the intestin

125 ngth, in vitro binding to everted intestinal sacs and quantitative in vivo uptake; this data suggests

126 ion to include DCR revisions, acute lacrimal sac abscesses, nasolacrimal duct obstructions in patient

127 ipants had acute dacryocystitis and lacrimal sac abscess presenting within 2 weeks of onset, who were

128 ive either percutaneous drainage of lacrimal sac abscess followed by EN-DCR after the acute episode s

129 ment after percutaneous drainage of lacrimal sac abscess in acute dacryocystitis.

130 etting of acute dacryocystitis with lacrimal sac abscess have not been well studied.

131 EN-DCR in acute dacryocystitis with lacrimal sac abscess results in faster resolution compared with s

132 ecirculation between the lungs and laryngeal sac.

133 endoleaks (45.1% vs 17.9%; P = .02) and late sac expansion (51.0% vs 21.4%; P = .01) and required mor

134 BRCA-mutant HGSOC, presence of PD in lesser sac (odds ratio [OR] = 2.40) and left upper quadrant (OR

135 come strangulated at its entry to the lesser sac via the foramen of Winslow was confirmed.

136 scan revealed a loop of ileum in the lesser sac.

137 tial for the separation of the jugular lymph sac from the cardinal vein and formation of the lymphove

138 elop via sprouting from venous-derived lymph sacs, vessels of lumbar and dorsal midline skin form via

139 ver-expressing Cyp26b1 had hypoplastic lymph sacs and lymphatic vessels.

140 hemorrhage as well as enlarged jugular lymph sacs and lymphatic vessels.

141 and leads to overgrowth of the jugular lymph sacs/primordial thoracic ducts, oedema and embryonic let

142 e veins to produce scattered primitive lymph sacs, from which most of the lymphatic vasculature is de

143 Mean sac diameter was 6.5+/-3.9 mm, and mean neck width was 2

144 in- and PI(4,5)P(2)-enriched apical membrane sac containing microvilli-like structures.

145 ymersomes are self-assembled hollow membrane sacs that are not only able to encapsulate hydrophobic a

146 ic hernias which are covered by a membranous sac.

147 e roots revealed the presence of microscopic sac-like root protuberances.

148 Moreover, multiple sac knockout mutants had an increased number of smaller

149 in echolocation to recycle air between nasal sacs.

150 of prominent camera-type eyes, paired nasal sacs, possible cranium and arcualia, W-shaped myomeres,

151 Moreover, we found that smt15-1, but not sac mutants, overaccumulates glutathione.

152 have been sub-optimal, as the importance of sac growth as a predictor of graft failure was overlooke

153 The fragmented vacuolar phenotype of sac mutants could be mimicked by treating wild-type seed

154 tively cover the bare bone around the opened sac, and provide a similar or even better clinical outco

155 ld place the patient at risk for endoleak or sac rupture.

156 an fluid and increased weight of the ovarian sac indicate disturbance of ovarian function.

157 statte, Yunnan Province, China, is an ovoid, sac-like metazoan that bears single-element spines on it

158 trauma by detecting blood in the pericardial sac.

159 e of a hemothorax and air in the pericardial sac.

160 t after EVAR to identify clinically relevant sac growth.

161 peritoneal fluid tracking into both scrotal sacs.

162 d with peritonitis tracking into the scrotal sacs was arrived at.

163 e sacs per miniature pig, for a total of six sacs).

164 In the prospective study, sac recanalization occurred between midterm and long-ter

165 Instead, the sac-like morphology invites comparison with the radially

166 inserted only into the amniotic fluid (three sacs per miniature pig, for a total of six sacs).

167 f sediment methane to inflate their tracheal sacs.

168 The retina, pineal, vascular sac, and pituitary were also targets of sbLPXRFa-ir cell

169 to float, limits the inflation of his vocal sac, and consequently reduces signal conspicuousness in

170 ysm three dimensions and volume, neck width, sac-to-neck ratio, initial result of embolization, numbe

171 Yolk sac erythro-myeloid progenitors (EMP) contribute substan

172 germ cell tumor with 85% embryonal, 10% yolk sac tumor, and 5% mature teratoma histologies.

173 hich revealed a 5-cm tumor that was 95% yolk sac tumor and 5% embryonal carcinoma, and retroperitonea

174 ell tumor predominantly consisting of a yolk sac element (Fig 1).

175 The human embryo retains a yolk sac, which goes through primary and secondary phases of

176 endoderm causes defects in the adjacent yolk sac mesoderm.

177 bilaminar disc formation, amniotic and yolk sac cavitation, and primordial germ cell-like cell (PGCL

178 bi-laminar disc formation, amniotic and yolk sac cavitation, and trophoblast diversification.

179 0,000 liver and 74,000 skin, kidney and yolk sac cells, we identify the repertoire of human blood and

180 mutagenesis in mice impaired neural and yolk sac ciliogenesis, leading to morphogenetic anomalies res

181 ase in the incidence of pericardial and yolk sac edema relative to controls.

182 that TRPM6 activity in the placenta and yolk sac is essential for embryonic development.

183 recursor cells of the embryo proper and yolk sac(1).

184 ein is a rodent-specific, placenta- and yolk sac-specific member of the tristetraprolin (TTP) family

185 vessel formation in the embryo body and yolk sac.

186 sp1-Cre(+) cells in both the embryo and yolk sac.

187 or example, most tissue macrophages are yolk sac derived, monocytes and macrophages follow a multidim

188 ecent paradigm shift that microglia are yolk sac-derived, not hematopoietic-derived, is reshaping our

189 ecific myeloid cell progenitors of both yolk sac and bone marrow origin.

190 bit WAF-exposed embryonic zebrafish but yolk sac edema was similar in all exposures.

191 In a chicken yolk sac membrane model, under the same ultrasound parameters

192 ipodystrophy and a history of childhood yolk sac tumour.

193 levels of VEGFA are observed in the cKO yolk sac, suggesting a cause for the angiogenesis defects.

194 Several of these mutants also display yolk sac vascular defects, suggesting a role for thrombin sig

195 r/colony-forming cells of the embryonic yolk sac (YS), which are endowed with megakaryocytic potentia

196 macrophages derived from the embryonic yolk sac and from fetal liver.

197 rimitive hematopoiesis in the embryonic yolk sac and self-renew throughout life.

198 derm (PrE), which forms extra-embryonic yolk sac tissues.

199 ification in the dorsal aorta, enhanced yolk sac hematopoiesis, and exuberant cardiac blood island fo

200 ion were confined to the YY1-expressing yolk sac mesoderm indicating that loss of YY1 in the visceral

201 hemangioblast as the cell of origin for yolk sac blood and endothelium.

202 Embryonic large molecule derived from yolk sac (ELYS) is a constituent protein of nuclear pores.

203 e-resident macrophages are derived from yolk sac erythromyeloid progenitors and fetal liver progenito

204 Embryonic SSMs originated from yolk sac hematopoiesis and were replaced by a postnatal wave

205 Resident macrophages are derived from yolk sac precursors and seed the liver during embryogenesis.

206 ent macrophages originally derived from yolk sac precursors.

207 progenitor pools, microglia arise from yolk sac progenitors and are widely considered to be equivale

208 rly embryogenesis, microglia arise from yolk sac progenitors that populate the developing central ner

209 ively self-renew and can be seeded from yolk sac/foetal liver progenitors with little input from mono

210 Functionally, yolk sac-derived chemokine (C-C motif) receptor 2(-) macropha

211 lidate the use of gestational sac (GS), yolk sac (YS) diameter, crown-rump length (CRL), and embryona

212 SC-derived haematopoiesis, and identify yolk sac EMPs as a common origin for tissue macrophages.

213 establishment of nascent vasculature in yolk sac and in the developing embryos.

214 Required histology included yolk sac, embryonal carcinoma, or choriocarcinoma.

215 rogenitors (EMPs) present in the murine yolk sac.

216 N629D/N629D yolk sac vessels and aorta consist of sinusoids without norma

217 -depletion strategy and fate-mapping of yolk sac (YS) and fetal liver (FL) hematopoiesis.

218 ogenesis is hallmarked by two phases of yolk sac development.

219 tify, in the fetal liver, a sequence of yolk sac EMP-derived and HSC-derived haematopoiesis, and iden

220 ll studied, the molecular regulation of yolk sac HE remains poorly understood.

221 xican-born mothers had a higher risk of yolk sac tumors (HR, 1.46; 95% CI, 0.99-2.17), while children

222 pulp macrophages, a discrete subset of yolk sac-derived macrophages, were found to be altered in SMA

223 f target transcripts in placenta and/or yolk sac, and that some of these would be important for femal

224 trophoblast giant cells in the parietal yolk sac.

225 ds to vascular defects in the placenta, yolk sac, and embryo proper, as well as abnormal neural tube

226 ar abnormalities in the lung, placenta, yolk sac, and retina.

227 different ontogenetic origins: prenatal yolk sac-derived Kupffer cells and peripheral blood monocyte-

228 The function of the primary yolk sac and the origin of extraembryonic mesoderm remain unc

229 sise that the hypoblast-derived primary yolk sac serves as a source for early extraembryonic mesoderm

230 blast gives rise to a transient primary yolk sac, which is rapidly superseded by a secondary yolk sac

231 2(+) macrophages derived from primitive yolk sac, recombination activating gene 1(+) lymphomyeloid, a

232 ating adult monocytes or from primitive yolk sac-derived macrophages.

233 ciated with worse outcome, whereas pure yolk sac tumor (YST) was associated with better outcome, alth

234 s broadly expressed across the RUNX1(+) yolk sac HE population compared with SOX17.

235 ch is rapidly superseded by a secondary yolk sac during gastrulation.

236 e exocoelomic cavity, and the secondary yolk sac function together as a physiological equivalent.

237 cies indicates that the human secondary yolk sac likely performs key functions early in development,

238 ferentiated derivatives, teratoma (TE), yolk sac tumor (YST), and choriocarcinoma.

239 arcinoma (PDAC) originate from both the yolk sac (YS) and bone marrow.

240 association in the blood islands of the yolk sac (YS).

241 rythromyeloid progenitors (EMPs) in the yolk sac and develop in the forming CNS.

242 evelopment, MCs enter the skin from the yolk sac and embryonic liver and are later mixed with cells o

243 originate during embryogenesis from the yolk sac and enter the CNS quite early (embryonic day 9.5-10

244 f cancer cells after injection into the yolk sac and extravasation of cancer cells into tissues from

245 opoietic progenitors located within the yolk sac and fetal liver as well as definitive hematopoietic

246 ties with microglial progenitors in the yolk sac and immature microglia in early embryos.

247 through primitive hematopoiesis in the yolk sac and migrate into the brain rudiment after establishm

248 from precursors originating within the yolk sac and migrate to the CNS under development, without an

249 from progenitor cells generated in the yolk sac and of 'passenger' or 'transitory' myeloid cells tha

250 the brain vasculature, like that of the yolk sac and the eye choriocapillaris and hyaloid vascular sy

251 the intricate relationship between the yolk sac and the primate embryo and highlight the pivotal rol

252 demonstrate that DPFCs originate in the yolk sac and then rapidly migrate to other extra- and intraem

253 o and highlight the pivotal role of the yolk sac as a multifunctional hub for haematopoiesis, germ ce

254 EMPs develop in the yolk sac at embryonic day (E) 8.5, migrate and colonize the n

255 ial in vitro have been described in the yolk sac before emergence of HSCs, and fetal macrophages can

256 Primitive hematopoiesis occurs in the yolk sac blood islands during vertebrate embryogenesis, where

257 of embryonic hematopoiesis such as the yolk sac by way of blood flow.

258 However F4/80(HI) macrophages from the yolk sac did not respond to LPS treatment.

259 a in the brain that originates from the yolk sac during early development.

260 The yolk sac is phylogenetically the oldest of the extraembryonic

261 ve paracrine signal, originating in the yolk sac mesoderm, is required to promote normal visceral end

262 enitors (EMPs) that first appear in the yolk sac of the early developing embryo.

263 mpounds into the embryonic body and the yolk sac of the zebrafish embryo using TK experiments, a dial

264 esins can be carefully implanted in the yolk sac of zebrafish embryos and display excellent biocompat

265 he blastoderm begins to spread over the yolk sac, a process involving coordinated epithelial surface

266 d animals (whole larvae, as well as the yolk sac, brain, and heart).

267 ythro-myeloid progenitors (EMPs) in the yolk sac, but it decreased the expression of alpha4-integrin

268 ducts of transient hematopoiesis in the yolk sac, dorsal aorta, and developing heart tube function at

269 multiple anatomical sites including the yolk sac, dorsal aorta, and heart tube.

270 tive endoderm (PE), which will form the yolk sac, is a crucial developmental decision.

271 cells termed haemogenic, present in the yolk sac, placenta and aorta, through an endothelial-to-haema

272 identifying the earliest stages in the yolk sac, throughout embryonic development and in all adult t

273 the extra-embryonic region to form the yolk sac, umbilical cord and placenta.

274 data for the coelomic fluid bathing the yolk sac.

275 acenta, and the epithelial cells of the yolk sac.

276 ch is derived the embryo proper and the yolk sac.

277 h the labyrinth of the placenta and the yolk sac.

278 innate lymphoid cell precursors in the yolk sac.

279 The putative progenitors of trMacs, yolk sac (YS) erythromyeloid progenitors, did not express IL7

280 C-(57)CoB12 accumulated in the visceral yolk sac of KO mice where megalin is expressed and provides a

281 e rise to chorio-allantoic and visceral yolk sac placentae, respectively.

282 e same in both WT and KO mouse visceral yolk sac, brain, and spinal column.

283 Predominant histology was yolk sac.

284 Whereas yolk sac-derived microglia reside in the brain, blood-derived

285 ave aberrant vasculogenesis in embryos, yolk sacs and placentas, and die between embryonic day 10.5 a

286 In the absence of Eng, yolk sacs inappropriately express the cardiac marker, Nkx2.5.

287 +/- KO caused defective angiogenesis in yolk sacs and embryos.

288 d caspase-3 were abnormally abundant in yolk sacs of Ripk1(D325A/D325A) embryos.

289 ck-out mice: no mature large vessels in yolk sacs, defective angiogenesis in the brain and intersomit

290 s, whereas there were few changes in KO yolk sacs.

291 (RNA-seq) data for the human and murine yolk sacs and compare those data with data for the chicken.

292 The defects in Osr1-null yolk sacs and embryos were virtually identical to those obser

293 Yolk-sac macrophages of EMP origin produced neonatal osteocla

294 Cx3cr1(+) yolk-sac macrophage descendants resided in the adult spleen,

295 that develop during organogenesis from yolk-sac erythro-myeloid progenitors (EMPs) distinct from hae

296 uropean sea bass (Dicentrarchus labrax) yolk-sac larvae was explored.

297 organs in which substantial numbers of yolk-sac macrophages persisted in adulthood.

298 macrophages are derived from primitive yolk-sac hematopoietic progenitors and exhibit hallmarks of M

299 Genetic fate mapping revealed that yolk-sac and fetal monocyte progenitors gave rise to the majo

300 ctivity in mammalian development is the yolk-sac blood island, which originates from the hemangioblas