ライフサイエンスコーパス: saccadic

1 These saccadic abnormalities related to DN involvement but wer

2 The saccadic abnormalities related to DN involvement were in

3 pects of oculomotion and delineates specific saccadic abnormalities that could be used to detect the

4 ect visual information efficiently relies on saccadic accuracy, which is limited by a combination of

5 ited anterior regions commonly attributed to saccadic action selection, including dorsolateral prefro

6 oscillatory activity in the hippocampus and saccadic activity in monkeys performing a recognition me

7 Jointly, the results indicate that extra-saccadic activity observed for free choice, and in previ

8 e essential for memory, is modulated by this saccadic activity, but the relationship between visual e

9 ction of stimulus-driven activity, increased saccadic activity, or enhanced representation of the opp

10 We observed that (1) saccadic adaptation can be induced by modifying target o

11 aze recalibration, similar to the well-known saccadic adaptation effect [9-11].

12 Such saccadic adaptation is usually induced by systematically

13 These results demonstrate that saccadic adaptation occurs even when the stimulus is alr

14 We used a miniaturized version of saccadic adaptation, an experimental procedure by which

15 from studies of vestibulo-ocular reflex and saccadic adaptation, we conclude that the plasticity at

16 m is considered to be critically involved in saccadic adaptation.

17 that cerebellar excitability is critical for saccadic adaptation.

18 found these were differentially accessed by saccadic and optokinetic inputs.

19 Both saccadic and perceptual report reaction times changed in

20 ther eye movements are derived from separate saccadic and vergence neural commands that control both

21 es of LIP neurons in two subjects with their saccadic behavior and three estimates of stimulus value.

22 ts to that of macaques, and found that their saccadic behavior is comparable across a number of sacca

23 In contrast, saccadic behavior when reading (forward and regressive s

24 of saccades is achieved within key cortical saccadic brain regions; (2) individual variability in co

25 otor nerves or nuclei, vertical supranuclear saccadic centres, and convergence neurons.

26 sical curve that tracks the evolution of the saccadic choice process with millisecond precision, and

27 ntal eye field (FEF) of monkeys performing a saccadic choice task and simulated the effects using a p

28 , saccade selection, saccade inhibition, and saccadic choice, in female and male human participants.

29 core network, however, was insufficient for saccadic choice, which recruited anterior regions common

30 d may not play a significant role in guiding saccadic choices informed solely by feature content.

31 that, contrary to expectations, during rapid saccadic choices perceptual information may directly mod

32 ver, the computational principles underlying saccadic choices remain poorly understood.

33 neurons further revealed that the brainstem saccadic circuitry controls these minute disconjugate sh

34 The proposed saccadic circuitry establishes a complete model of sacca

35 This saccadic continuum extended to nonrestrictive, ecologica

36 model of oculomotor behavior can explain the saccadic continuum from exploration to fixation, for ima

37 rker panel (neuropsychological, stop signal, saccadic control, and auditory stimulation paradigms) ch

38 e, and in previously published tasks probing saccadic control, is likely due to increased load on hig

39 ed to higher-level cognitive demands and not saccadic control.

40 untermanding stimuli, such as those in large saccadic countermanding tasks: they cancel an upcoming m

41 dback, this information was provided by each saccadic decision threshold, which represented the total

42 However, saccadic decisions are often studied in isolation, which

43 In monkeys making saccadic decisions based on motion cues and asymmetric r

44 fine-grained temporal analysis of human peri-saccadic detection performance in an attention task, we

45 Under more natural conditions, trans-saccadic displacement detection is as good as in fixatio

46 gh a saccade-contingent habituation to intra-saccadic displacements.

47 We used a novel saccadic distraction task to quantify the speed and accu

48 However, after exposure to a post-saccadic disturbance or a context without any intra-sacc

49 sed either to an intra-saccadic or to a post-saccadic disturbance or to no disturbance at all.

50 after participants were exposed to an intra-saccadic disturbance.

51 ce for CD in primates comes largely from the saccadic double-step task, which requires participants t

52 salience and value information influence the saccadic end point within an object, but with different

53 nty produced not only a larger spread of the saccadic endpoints but also more hypometric errors and a

54 porally dissociate the visual epoch from the saccadic epoch through a delay epoch, and used the local

55 led way and to minimize the expected cost of saccadic errors.

56 to control for the direct effects of TDCS on saccadic execution.

57 How the pre-saccadic extrafoveal preview of a visual object influenc

58 bles the redistribution resulting from inter-saccadic eye drifts, revealing a continuum in the modula

59 Using the saccadic eye movement as a probe, we provide results tha

60 perficial SC, suggesting a novel pathway for saccadic eye movement choice.

61 ed manual button press (humans) or a speeded saccadic eye movement response (humans and monkeys).

62 Every saccadic eye movement that we make changes the image of

63 inaccurately represent eye position during a saccadic eye movement, and to be too slow to support a r

64 y to select the task-relevant stimulus for a saccadic eye movement, while inhibiting saccades to task

65 mifield to the other because of a horizontal saccadic eye movement.

66 Saccadic eye movements "bring" eccentric targets to the

67 alled oculomotor range that is accessible by saccadic eye movements [5,6].

68 times, we measured visual sensitivity before saccadic eye movements and during fixation at locations

69 olation by performing combined recordings of saccadic eye movements and fast event-related fMRI durin

70 ng target are slower and longer lasting than saccadic eye movements and it has been suggested that in

71 nts, beyond its traditional roles in guiding saccadic eye movements and localizing attention.

72 implicated as a salience map for control of saccadic eye movements and visual attention.

73 here sensorimotor transformations leading to saccadic eye movements are implemented in the brain, les

74 hanism are compatible with the rate at which saccadic eye movements are typically observed in natural

75 The frequency of these saccadic eye movements belies the complexity underlying

76 elp gate the transition between fixation and saccadic eye movements by monosynaptically suppressing a

77 nt contributions to our understanding of how saccadic eye movements can be rapidly inhibited, changed

78 rience seems continuous and detailed despite saccadic eye movements changing retinal input several ti

79 When saccadic eye movements consistently fail to land on the

80 Saccadic eye movements direct the high-resolution foveae

81 To examine the speed and accuracy of saccadic eye movements during a novel eye tracking thres

82 Saccadic eye movements facilitate rapid and efficient ex

83 Participants were asked to make saccadic eye movements for different monetary rewards, w

84 This study examines the consequences of saccadic eye movements for the internal representation o

85 participants to make two visually triggered saccadic eye movements in brief succession.

86 upled between the eyes, similar to conjugate saccadic eye movements in humans.

87 s (MD) conveys oculomotor CD associated with saccadic eye movements in nonhuman primates.

88 A key structure for directing saccadic eye movements is the superior colliculus (SC).

89 This study aims to determine whether the saccadic eye movements of people with glaucoma differ fr

90 Saccadic eye movements play a central role in primate vi

91 Saccadic eye movements provide a valuable model to study

92 During visual exploration, saccadic eye movements scan the scene for objects of int

93 Our studies show mice make saccadic eye movements spontaneously and in response to

94 he monkeys to occasionally withhold planned, saccadic eye movements to a visual target.

95 umans actively sample their environment with saccadic eye movements to bring relevant information int

96 Animals can make saccadic eye movements to intercept a moving object at t

97 s and other animals with foveate vision make saccadic eye movements to prioritize the visual analysis

98 We understand the world by making saccadic eye movements to various objects.

99 Humans perform saccadic eye movements two to three times per second.

100 ll amplitude, nasally directed (ipsiversive) saccadic eye movements were evoked by microstimulation i

101 r to the anterior frontal sulcus, from which saccadic eye movements were evoked with electrical stimu

102 ked by SC stimulation as well as spontaneous saccadic eye movements were larger in the dark-reared mi

103 Saccadic eye movements were measured using infra-red ocu

104 ectrical microstimulation to the SC, so that saccadic eye movements were not evoked.

105 icant increase in the probability of evoking saccadic eye movements when low current electrical stimu

106 ause of the rapid and reproducible nature of saccadic eye movements, and the key role that they play

107 We explore the visual world through saccadic eye movements, but saccades also present a chal

108 erience the visual world through a series of saccadic eye movements, each one shifting our gaze to br

109 In monkeys deciding between alternative saccadic eye movements, lateral intraparietal (LIP) neur

110 During saccadic eye movements, the job of the nervous system is

111 tes learning of image statistics and directs saccadic eye movements, we propose that the acquisition

112 We examined whether the preparation of saccadic eye movements, when behaviorally dissociated fr

113 le, expectation of reward increases speed of saccadic eye movements, whereas expectation of effort de

114 rontal eye field (FEF) carries such a CD for saccadic eye movements.

115 brain forms decisions comes from studies of saccadic eye movements.

116 r on object recognition) to the precision of saccadic eye movements.

117 a V4 of nonhuman primates trained to execute saccadic eye movements.

118 more natural conditions, they make frequent saccadic eye movements.

119 onkeys that is triggered by the execution of saccadic eye movements.

120 esponse field (RF) stimuli are targeted with saccadic eye movements.

121 t of the BG-brainstem projection controlling saccadic eye movements.

122 explore the visual world through the use of saccadic eye movements.

123 ial functions, such as spatial attention and saccadic eye movements.

124 retina and serially sample visual scenes by saccadic eye movements.

125 visuospatial attention may be linked through saccadic eye movements.

126 atable behavioral deficits in the metrics of saccadic eye movements.

127 of visual targets flashed around the time of saccadic eye movements.

128 s), and electrical stimulation of CDt evokes saccadic eye movements.

129 sms underlying the planning and execution of saccadic eye movements.

130 ogram (RDK) paradigm and recordings of their saccadic eye movements.

131 n: preferential routing of sensory input and saccadic eye movements.

132 flects the planning of behaviorally relevant saccadic eye movements.

133 ld as stable, although we constantly perform saccadic eye movements?

134 A sequence of saccadic eye-movement vectors, moving from one salient f

135 Here, human participants used saccadic-eye and hand-pointing movements to report recog

136 at fatigue can affect the characteristics of saccadic (fast ballistic) eye movements in nonsurgical s

137 cy at processing the information in the post-saccadic fixation, but is independent of neuronal reward

138 is; psychomotor functioning (using the Wayne Saccadic Fixator (WSF)); and adverse events.

139 Environment and dual-task impacted on saccadic frequency especially for PD.

140 For both groups, saccadic frequency increased when approaching a turn com

141 Increased saccadic frequency was related to poorer attention, cogn

142 Visual sampling (saccadic frequency) and gait were measured concurrently

143 during nonadaptation sessions did not affect saccadic gain, velocity, or duration, demonstrating that

144 oculomotor profile (e.g. exacerbation of the saccadic gap/overlap effect, preserved saccadic velocity

145 and 26 healthy control subjects completed a saccadic Go/No-Go task with a head-mounted infrared sacc

146 is not contingent on prior selection of the saccadic goal by visually driven FEF responses.

147 Avian saccadic head/eye movements have been shown to vary cons

148 hip between pre-saccadic "previews" and post-saccadic images to explicitly isolate the influences of

149 These results support the hypothesis that saccadic indices reflect graded changes in fatigue.

150 Blinks effectively remove saccadic inhibition and prematurely trigger impending sa

151 us FEF alpha-band power predicted successful saccadic inhibition.

152 their retinotopic location in time for post-saccadic input, validating dynamic predictive coding the

153 lly generally were most persistent following saccadic input, whereas cells located rostrally were mos

154 t temporoparietal cortex is modulated during saccadic interrogation of a simple visual scene.

155 entral attention networks changed during the saccadic interrogation of a simple visual scene.

156 with posterior cortical atrophy showed large saccadic intrusions whose frequency correlated significa

157 Older subjects had significantly increased saccadic latencies (at all locations; P < 0.05), decreas

158 such as Huntington disease produce increased saccadic latencies and impaired suppression of saccades

159 The model decomposes saccadic latencies into parameters for the decision proc

160 We used a saccadometer to measure the saccadic latencies of 9 DBS patients (1) preoperatively,

161 The ALS group also showed reduced saccadic latencies that correlated with increased activa

162 s underlying disinhibition, using horizontal saccadic latencies that obviate the impact of limb slown

163 Mean saccadic latencies were similar between all three groups

164 Saccadic latency and accuracy are related to visual thre

165 related to visual threshold, suggesting that saccadic latency and accuracy could be useful as perimet

166 Since this saccadic latency can be rapidly and objectively measured

167 Saccadic latency increased as stimulus size decreased in

168 stimulator is turned on, but in the case of saccadic latency the pattern is different: surgery produ

169 we evaluated for group-level differences in saccadic latency, accuracy, and visual threshold at each

170 han or equal to 10% in all six EOMS even for saccadic loading rates.

171 sponses to predicted stimuli at the new post-saccadic location in V1.

172 ant signal for saccadic system and its trans-saccadic manipulation entails considerable changes at mu

173 n evoked activity is consistent with a trans-saccadic mechanism of prediction that influences categor

174 complex interplay between visual and central saccadic mechanisms during reading.

175 ced by time-on-duty (~24 hours) might affect saccadic metrics in surgical residents.

176 Saccadic mislocalization, by contrast, is robust and res

177 s were distinct from the neurons' visual and saccadic modulations and from signals of expected reward

178 Therefore, a TMS pulse centrally perturbs saccadic motor commands, which are monitored possibly vi

179 humans, flies generate both smooth and rapid saccadic movements to stabilize their gaze.

180 However, the post-saccadic N170 was strongly attenuated following intact-f

181 timulus relevant information; and (2) that a saccadic neural marker for a saccade target stimulus cou

182 ent) resulted in a massive reduction of post-saccadic neural responses.

183 Here we show how premotor saccadic neurons control these small fixational eye move

184 lation causes prolonged excitation of visual-saccadic neurons in the superior colliculus (SC), and in

185 pendence we quantify and its link with trans-saccadic object perception instead suggest that feature

186 t converts time-varying retinal signals into saccadic oculomotor commands.

187 y at saccadic onset and an enhancement after saccadic offset.

188 the motion created by our own eye movements-saccadic omission.

189 uce a suppression of contrast sensitivity at saccadic onset and an enhancement after saccadic offset.

190 it is crucial that saccadic suppression and saccadic onset be temporally synchronous.

191 sion was measured between -50 and 50 ms from saccadic onset.

192 d throughout the oculomotor integrator after saccadic or optokinetic stimulation.

193 participants were exposed either to an intra-saccadic or to a post-saccadic disturbance or to no dist

194 Practice on peri-saccadic orientation discrimination led to long-lasting

195 We also explored associations between saccadic outcomes and clinical measures.

196 me (8), INO (20), one and half syndrome (3), saccadic palsy (28), and smooth pursuit palsy (46).

197 te the contribution of other areas, abnormal saccadic parameters were compared with global and region

198 ion between motivation level and rewards for saccadic peak velocity (F2,18=5.153, p=0.049), with the

199 ts on medication demonstrated an increase in saccadic peak velocity as reward magnitude increased (an

200 nergic drugs, both in pupillary response and saccadic peak velocity response to reward.

201 group exhibiting less reward sensitivity in saccadic peak velocity.

202 red if this could also be the case with peri-saccadic perception.

203 maging, and a large subset performed a trans-saccadic perceptual task that yields measures of CD.

204 atrophy, and highlights multiple aspects of saccadic performance which distinguish posterior cortica

205 and typical Alzheimer's disease were seen in saccadic performance.

206 In a saccadic planning task, we observed that distinct behavi

207 ing that prior knowledge was integrated into saccadic planning.

208 al information may directly modulate ongoing saccadic plans, and this process is not contingent on pr

209 ate that crowding, spatial localization, and saccadic precision show clear dissociations, indicative

210 Therefore, pre-saccadic predictions update their retinotopic location i

211 signals (indicative of an impairment in the saccadic premotor pathway), whereas abducens activation

212 The results show that saccadic preparation and visual sensitivity oscillations

213 The results show that saccadic preparation and visual sensitivity oscillations

214 We manipulated the relationship between pre-saccadic "previews" and post-saccadic images to explicit

215 importance of peripheral vision during trans-saccadic processing in building a coherent and stable re

216 eview of a visual object influences its post-saccadic processing is still an unanswered question.

217 Spatial attention and saccadic processing therefore co-ordinate well to ensure

218 Other saccadic properties varied as function of image size as

219 s, whereas Wilson disease is associated with saccadic pursuits, increased antisaccade latencies and d

220 Saccadic rates during exploration are higher than those

221 s in SC activity to concomitant increases in saccadic reaction time (SRT).

222 Primary outcome measures included average saccadic reaction time in a visually guided saccade proc

223 but overlapping with target onset shortened saccadic reaction times (RTs) for ipsiversive (to the st

224 earlier peak in the AST distribution of the saccadic reaction times for the inhibitory errors in com

225 ngs showed for the first time that newborns' saccadic reaction times to a tactile stimulus simultaneo

226 in 8Av (close to FEF) shortened or prolonged saccadic reaction times, depending on the task-instructe

227 We found that these measures were related to saccadic reaction times, suggesting that the population-

228 onal weighting of saccade targets as well as saccadic reaction times.

229 Saccadic response speeds were used to estimate the param

230 ayesian model fitted to individual trialwise saccadic response speeds.

231 indexed motivation level using pupillary and saccadic response to monetary incentives, allowing rewar

232 ANCE STATEMENT Failures to inhibit automatic saccadic responses are a hallmark of many neuropsychiatr

233 dity varied in time and the targets required saccadic responses.

234 n might explain why we do not perceive trans-saccadic retinal stimulation during saccades.

235 (PCC) in 2 male rhesus monkeys performing a saccadic reward task.

236 However, saccadic sampling has largely been explored in paradigms

237 , in contrast to previously published tasks, saccadic selection and inhibition recruited only this co

238 on higher-level cognitive processes, and not saccadic selection per se, which is achieved within the

239 the view that objects are important units of saccadic selection.

240 logic eye oscillations while allowing normal saccadic shifts of gaze.

241 ll known that the medial cerebellum controls saccadic speed and accuracy.

242 to be related to the problem of maintaining saccadic stability.

243 the action of special mechanisms conferring saccadic stability.

244 c disturbance or a context without any intra-saccadic stimulation, displacement discrimination improv

245 on experiment: the Wheeless task, in which a saccadic stimulus is followed after a short delay by a s

246 ted by the eye movements, it is crucial that saccadic suppression and saccadic onset be temporally sy

247 ide a quantitative description of behavioral saccadic suppression and thereby allow a more focused se

248 The brain might accomplish saccadic suppression by reducing the gain of visual resp

249 The different saccadic suppression in the two cell types points to dif

250 This selective saccadic suppression is because of the selective targeti

251 This saccadic suppression is thought to be a mechanism for ma

252 jects remain stable or move, which is called saccadic suppression of displacement (SSD).

253 lacement thresholds usually observed in the "saccadic suppression of displacement" paradigm are a res

254 ergic circuits within the retina can produce saccadic suppression of retinal ganglion cell activity.

255 We suggest that saccadic suppression originates from efficient sensorimo

256 lysis of the synaptic inputs shows that this saccadic suppression results from glycinergic inputs tha

257 This pattern of results suggests that saccadic suppression shares some of the circuitry respon

258 These results suggest that saccadic suppression shares the brain circuits responsib

259 Strong saccadic suppression was measured between -50 and 50 ms

260 es in attention, visual image stability, and saccadic suppression, but in contrast to feedforward pat

261 One clear case is saccadic suppression, the reduced visibility around the

262 e answer in part is a brain mechanism called saccadic suppression, which reduces the responses of vis

263 This laboratory phenomenon--behavioral saccadic suppression--is thought to underlie the everyda

264 ction of a specific context, I measured peri-saccadic suppression.

265 s suggest that size is a relevant signal for saccadic system and its trans-saccadic manipulation enta

266 uss the "predictive" properties of the visuo-saccadic system and the nature of this location where th

267 olliculus (SC), but they also disinhibit the saccadic system by removing the potent inhibition of pon

268 ken together, these findings reveal that the saccadic system uses a probabilistic-Bayesian control st

269 We removed downstream inhibition on the saccadic system using the trigeminal blink reflex, trigg

270 pression was absent when the features of the saccadic target matched the features preferred by indivi

271 ision formation emerged from studies where a saccadic target was always stimulating the RF during dec

272 cause compression of visual space around the saccadic target, and also a compression of time, both ph

273 the briefly presented stimulus closer to the saccadic target.

274 orientation of both the RF stimulus and the saccadic target.

275 n of saccades depends on the features of the saccadic target.

276 control area massively converge towards the saccadic target.

277 saccades and less about the features of the saccadic target.

278 orizontal saccades at will to two stationary saccadic targets separated by 20 degrees .

279 Time to reach saccadic targets was significantly associated with parie

280 y manipulating the positional uncertainty of saccadic targets.

281 he two brain regions in monkeys performing a saccadic task with dynamically changing reward locations

282 ubject by their performance in a simple step saccadic task, which identifies the two free parameters

283 Despite using currents well above saccadic thresholds of the directly adjacent Frontal Eye

284 e another; (4) the FM subsystem superimposes saccadic turns upon smooth pursuit; and (5) the two syst

285 preted as indicating that LIP neurons encode saccadic value and that they mediate value-based decisio

286 traparietal cortex encode a relative form of saccadic value, explicitly dependent on the values of th

287 perimetry (SAP) and eye tracking perimetry (saccadic vector optokinetic perimetry, SVOP) was perform

288 Time-on-duty decreased saccadic velocity and increased subjective fatigue but d

289 These findings demonstrate that saccadic velocity and pupil diameter are affected by rew

290 Saccadic velocity and pupil modulation by reward were us

291 voluntary control, a fatigue index based on saccadic velocity has the potential to provide an accura

292 Our data show, for the first time, that saccadic velocity is a reliable indicator of the subject

293 Because saccadic velocity is not under voluntary control, a fati

294 mine, they had greater response vigour (peak saccadic velocity residuals) for contingent rewards, whe

295 f the saccadic gap/overlap effect, preserved saccadic velocity) reflects weak input from degraded occ

296 nal effects were indexed by pupillometry and saccadic velocity, and patients were tested ON and OFF d

297 We found that in humans, saccadic vigor, assessed using velocity as a function of

298 al system has adapted to compensate for peri-saccadic vision changes.

299 Peri-saccadic vision is also characterized by a mislocalizati

300 mmonly viewed as obligatory elements of peri-saccadic vision.