ライフサイエンスコーパス: sad

1 Finally, of the 24 sad mutants analysed in this study, only three had defec

2 ibrosis, respiratory failure and death are a sad reality.

3 g the following: mental health conditions; a sad or depressed mood; substance abuse problems; medical

4 It is a sad reality that although eminently preventable, and des

5 ng while they alternated between recalling a sad, ruminative thought about their loved one (grief sta

6 ("Al") Gilman, M.D., Ph.D., represents a sad signpost for an era spanning over 40 years in molecu

7 rent common facial expressions: the smile, a sad expression and an expression of horror, and three co

8 The wild-type allele, sad-1(+), encodes a putative RNA-directed RNA polymerase

9 feeling confused (43% vs. 22%, p = .004) and sad (46% vs. 31%, p = .04) and less likely to report bei

10 (happy, surprise, fear, disgust, anger, and sad) using the same facial movements by virtue of their

11 bidirectional frontotemporal connections and sad faces modulating unidirectional fusiform-orbitofront

12 Expression of dib and sad continues to be localized in this endocrine compartm

13 Unlike dib and sad, shd is not expressed in the ring gland but is expre

14 When cells are transfected with both dib and sad, they metabolize the [3H]ketotriol to [3H]E in high

15 ched videos depicting cocaine, gambling, and sad scenarios to investigate the neural correlates of cr

16 isation severity consisted in both happy and sad conditions of the anterior ventral precuneus (BA7),

17 esented with facial expressions of happy and sad emotion at three intensity levels (0%-50%-100%) in a

18 erior cingulate difference between happy and sad emotion regulation.

19 ective connectivity in response to happy and sad face emotions, despite normal activations within eac

20 changes in amygdalar responses to happy and sad faces and improved processing of positive stimuli du

21 The opposite was observed for happy and sad faces, where greater thalamic and midfrontal activat

22 ent, we assessed pupil dilation to happy and sad facial expressions (n = 152 trials).

23 cognition accuracy (percentage) of happy and sad facial expressions at 10 weeks assessed with the fac

24 We created second-order faces with happy and sad facial expressions specified solely by local directi

25 ns modulate autonomic responses to happy and sad facial expressions, evidenced by changes in pupil si

26 position, I discuss the effects of happy and sad moods on discourse and sentence comprehension.

27 and we compare people with induced happy and sad moods.

28 blunted emotional response to both happy and sad musical excerpts.

29 lts support an interplay of inflammation and sad mood on striatal and hippocampal circuitry engaged d

30 n effects of acute systemic inflammation and sad mood on the expectation and experience of visceral p

31 , showing angry, fearful, happy, neutral and sad emotions, and had to assess which emotion was shown,

32 d then continuously rated happy, neutral and sad pieces of music whilst undergoing MRI scanning.

33 nts, gambling videos in PG participants, and sad videos in control participants.

34 encoding an RNA-directed RNA polymerase, and sad-2, encoding a protein that controls the perinuclear

35 rall micro expression recognition scores and sad face recognition, and a bias towards recognizing neu

36 nted infrequently as attentional targets and sad and neutral pictures as novel distractors.

37 "surprise," "fear," "disgust," "anger," and "sad"-and judge their intensity in two distinct cultures

38 iated with identification of fearful, angry, sad, happy, and neutral faces using a large sample of 75

39 iated with identification of fearful, angry, sad, happy, and neutral faces, and reveal aspects of bra

40 rocessing of emotional speech (happy, angry, sad and neutral) in the left hemisphere of 21 two-month-

41 and categorization of fearful, happy, angry, sad, and neutral facial expressions.

42 On each treatment, brain responses to angry, sad, and neutral faces were measured with functional mag

43 , tired, short of breath, restless, anxious, sad, hungry, scared, thirsty, confused).

44 We are sad to report that Professor Jacob (Jack) Nachmias passe

45 a bias towards recognizing neutral faces as sad.

46 subjects more frequently perceived faces as sad.

47 g with posterior cingulate gyrus (PCC, BA23, sad condition) and anteromedial thalamus (happy conditio

48 In every medical specialty bad, sad, and difficult information must be given to patients

49 of two marker genes for lipid biosynthesis (sad and ear) occurred at a bud length of 2-3 mm, and the

50 mporal brain network, whereas mood congruent sad information was associated with less network modulat

51 are designated surface attachment defective (sad ).

52 which we term surface attachment defective (sad).

53 The resulting substrate adhesion-deficient (sad) mutants grew in plastic dishes without attaching to

54 hree members of the stearoyl-ACP desaturase (sad) gene family by Northern blotting, in situ hybridiza

55 d anterior (p(FWE) = 0.041) cingulate during sad face emotion processing.

56 and reduced top-down cortical control during sad emotion processing.

57 tivity in left inferior frontal gyrus during sad face inhibition, demonstrating bipolar trait effects

58 in an experimentally induced negative (i.e., sad) and in a neutral mood state, accomplished in balanc

59 Inactivation of either sad-1 or sad-2 suppresses MSUD.

60 y in response to emotionally valenced faces (sad, fearful, angry, happy, neutral) following a negativ

61 pants inhibited the response to happy faces, sad faces, or letters.

62 they viewed a two-by-two matrix of fearful, sad, happy, and neutral facial expressions before they w

63 uicidality in the previous year (ie, feeling sad for 2 weeks and considering suicide, planning suicid

64 ociated with increases in reports of feeling sad (P < .001) or angry (P = .01).

65 Fathers also reported feeling sad, hurt, or angry when providers were nonchalant and i

66 Only 22/131 (16%) fathers reported feeling sad, hurt, or angry.

67 ideotapes designed to elicit happy feelings, sad feelings, or the desire to use cocaine.

68 m caspase inhibitor Z-Val-Ala-Asp (ome)-FMK (sad) was given, and cardiac function was determined in i

69 -3.92 to 2.84; P = .72; Cohen d = -0.05) for sad facial expressions.

70 were associated with inhibitory deficits for sad and neutral, but not for happy expressions.

71 nd two RBPs are combinatorially required for sad-1 exon inclusion.

72 ation time and longer mean fixation time for sad faces predicted higher depressive symptom scores.

73 A functional sad-2(+) gene is necessary for SAD-1 localization, but t

74 olve emotions of daily social living (e.g., "sad", "joy"), the imagination (e.g., "psychedelic", "mys

75 maximal expression of the lipid marker genes sad, ear, acp and cyb5 was at the 3-5 mm bud stages, wit

76 me of the research on the impact that giving sad, bad, and difficult news has on doctors and patients

77 to 5 target emotions: angry, anxious, happy, sad, and neutral.

78 tially in the four target conditions (happy, sad, angry and fearful) along the dimension of threat-re

79 uring implicit processing of emerging happy, sad, fearful and angry faces and shapes.

80 ects viewed images designed to induce happy, sad, and neutral emotional states.

81 ciated with correct identification of happy, sad, angry and fearful faces.

82 FEP Task that measures recognition of happy, sad, angry, fearful, and neutral emotions.

83 ented mild and extreme intensities of happy, sad, angry, fearful, disgusted, and neutral faces, balan

84 d with neutral faces (event related): happy, sad, anger, and fear.

85 d comparison among neural response to happy, sad, and neutral words, in the context of these words as

86 in new mothers when viewing emotional (happy-sad) faces contrasted to neutral faces.

87 ked them to apply shade where they had happy/sad memories, and where they wanted to go after Covid-19

88 In sad-1 mutant animals presynaptic vesicle clusters in sen

89 etermine presynaptic assembly is impaired in sad-1 mutants and increased by overactivation of SAD-1.

90 Sensory axons fail to terminate in sad-1 mutants, whereas overexpression of SAD-1 causes se

91 groups had a greater response to inhibiting sad faces in emotion processing and regulation regions,

92 al states: happy, tender, afraid, irritated, sad, and no emotion.

93 lex splicing patterns in the neuronal kinase sad-1.

94 y contact with relative, and feeling lonely, sad or depressed using multinomial logistic regression.

95 g masked happy faces but decreased to masked sad faces in the experimental versus control group follo

96 reater amygdala responses than HCs to masked sad faces, whereas HCs showed greater amygdala responses

97 While viewing both masked-sad and masked-happy faces relative to masked-neutral fa

98 wed distinct hemodynamic responses to masked-sad and masked-happy faces in neural circuits known to s

99 r BOLD responses than the controls to masked-sad versus masked-happy faces in the hippocampus, amygda

100 d the impact of experimentally induced mood (sad, neutral) on plasma IL-18 and relationships with con

101 3.9%-48.3%] of females reported feeling more sad) and anxiety (21.8% [95% CI, 18.2%-25.8%] of males v

102 Moreover, sad vocalizations modulated the activity of brain region

103 which are found to be dominated by negative, sad conceptual associations in analyses based on subject

104 inatorial TF-RBP code controls single-neuron sad-1 splicing.

105 s felt societal pressure to be happy and not sad is particularly linked to poor well-being in countri

106 te how societal pressure to be happy and not sad predicts emotional, cognitive and clinical indicator

107 angry vs. neutral and angry vs. sad but not sad vs. neutral faces.

108 emotional responses to stimuli that were not sad.

109 ith faster avoidance relative to approach of sad faces.

110 Two classes of sad mutants were analysed: (i) mutants defective in flag

111 The expression of sad and dib is concentrated within the individual segmen

112 We found that increasing intensity of sad facial expression was associated with enhanced activ

113 n also resulted in higher arousal ratings of sad stimuli.

114 s of sociability and enhanced recognition of sad facial expressions.

115 Transcripts of sad-1(+) can be detected during the sexual phase in a ho

116 th BD performed worse than those with MDD on sad emotion regulation but normal on happy emotion regul

117 Inactivation of either sad-1 or sad-2 suppresses MSUD.

118 ubjective responses to the happy (P =.56) or sad (P =.81) videotapes.

119 tapes but not in patients watching happy or sad tapes or in healthy subjects under any condition.

120 ttribution to a target-face (either happy or sad) depending on the social context.

121 ideotaped scenarios with gambling, happy, or sad content.

122 l neural response to emotional, particularly sad, distractors in the lateral orbitofrontal cortex.

123 the amygdala toward face stimuli portraying sad expressions that is evident even when such stimuli a

124 red for MSUD have been described previously: sad-1 (suppressor of ascus dominance), encoding an RNA-d

125 ated a second gene involved in this process, sad-2.

126 ence than in late childhood while processing sad and happy versus neutral faces.

127 ation rates and response bias in recognising sad facial expressions, but higher accuracy and response

128 Patients with MDD regulated sad and happy emotions poorly compared with those with B

129 those seen in disembodied (dib) and shadow (sad) mutants, two other genes of the Halloween class tha

130 yonic lethals, disembodied (dib) and shadow (sad), code for mitochondrial cytochromes P450 that media

131 onal MRI as they viewed face stimuli showing sad, happy or neutral face expressions, presented using

132 ion by narrative type: semantically similar, sad autobiographical memories elicited similar neural re

133 omprised feelings of hopelessness (feeing so sad or hopeless that you stopped doing activities), nons

134 tendencies in response to different stimuli (sad/happy faces and social scenes) at three time points

135 sicle proteins to dendrites, suggesting that sad-1 affects axonal-dendritic polarity as well as synap

136 rugator and depressor anguli oris during the sad look and the frontalis and mentalis during the horro

137 rugator and depressor anguli oris during the sad look, the frontalis and mentalis during the horror l

138 mood on a visual analog scale following the sad mood induction procedure (MIP).

139 Critical care professionals know the sad reality behind the statistical scarcity of organ sup

140 activity were observed during viewing of the sad and happy scenarios, they were distinct from those c

141 Molecular analysis of the sad mutants revealed that the ClpP protein (a component

142 Amygdala hyper-reactivity to sad emotion is involved in a specific non-response to a

143 .63, -0.51) that contribute to reactivity to sad mood and therefore vulnerability to depression, and

144 findings of improved cognitive reactivity to sad mood following chronic probiotic supplementation, in

145 ety, depression, and cognitive reactivity to sad mood.

146 nt increase in pupil dilation in response to sad and not happy expressions.

147 hether the amygdala has a neural response to sad and/or angry facial expressions.

148 d activity in parietal cortex in response to sad faces but no differences in brain activity in a prio

149 Aberrant amygdala activation in response to sad facial emotions is specific to the depressed state a

150 cutely enhancing right amygdala responses to sad (compared with neutral) faces (p = 0.032) and anti-T

151 cutely enhancing right amygdala responses to sad (compared with neutral) faces (p = 0.032) and anti-T

152 neural substrates which mediate responses to sad and angry expressions.

153 assessment predicted increased responses to sad faces in amygdala, hippocampal, parietal, and orbita

154 abolished the abnormal amygdala responses to sad faces in currently depressed patients but did not al

155 essing biases occur in amygdala responses to sad faces presented below the level of conscious awarene

156 sed bilateral amygdala responses specific to sad faces relative to healthy comparison subjects and no

157 tients showed elevated responses specific to sad targets in rostral anterior cingulate extending to a

158 sponse to attentional targets rather than to sad distractors.

159 probe video task was used to index AB toward sad film clips.

160 The bias toward sad faces also was evident in rMDD participants relative

161 eers were studied before and after transient sad mood challenge.

162 Compared with viewing sad and amusing films, the episodes were associated with

163 In healthy volunteers, sad faces modulated bi-directional connections between a

164 MDD and BD differed with regard to happy vs sad emotion regulation (t = 4.19; P < .001; Cohen d = 1.

165 n processing angry vs. neutral and angry vs. sad but not sad vs. neutral faces.

166 e active in healthy subjects when they watch sad tapes than when they watch happy tapes, suggesting a

167 elicited under standard conditions (watching sad and amusing emotional films, being startled); and (i

168 ormal in cocaine-dependent subjects watching sad tapes, suggesting more general affective dysregulati

169 When sad (CYP315A1) is transfected into Drosophila S2 cells,

170 mbles an expression that humans produce when sad, so its production in dogs may trigger a nurturing r

171 ctivity while regulating happy compared with sad emotions.

172 sure expression of RBPs, which interact with sad-1 pre-mRNA.

173 ndition combining an inflammatory state with sad mood and in control conditions.

174 with the birth of your child?" and "Are you sad, hurt or angry today about something personnel did i