ライフサイエンスコーパス: salvage pathway

1 oducing (d)IMP that can enter the nucleotide salvage pathway.

2 l regulation of cell death by the methionine salvage pathway.

3 that INAM increases flux through the NAD(+) salvage pathway.

4 se in the recycling of the backbones via the salvage pathway.

5 -gamma-methiolbutyrate closes the methionine salvage pathway.

6 es from the de novo pathway and 20% from the salvage pathway.

7 er, R. rubrum lacks the classical methionine salvage pathway.

8 osphate, an important step in the pyrimidine salvage pathway.

9 ion of ethylene, a product of the methionine salvage pathway.

10 ly available to be absorbed and used for the salvage pathway.

11 ted by repletion of CTP through the cytidine salvage pathway.

12 tion of ARDs is to operate in the methionine salvage pathway.

13 de and generates NAD+ through an alternative salvage pathway.

14 to refill the internal GMP pool through the salvage pathway.

15 sphorylase is a key enzyme in the pyrimidine salvage pathway.

16 sing the de novo biosynthesis pathway or the salvage pathway.

17 d from M. bovis, demonstrating a functioning salvage pathway.

18 critically requires the deoxyribonucleoside salvage pathway.

19 MA-induced formation of ceramide through the salvage pathway.

20 ase (Nampt) is a rate-limiting enzyme in the salvage pathway.

21 hosphorylase, a key enzyme in the methionine salvage pathway.

22 at provides a rate-limiting step in the NAD+ salvage pathway.

23 acterized, one of which is linked to a novel salvage pathway.

24 dition, the chloroplast has an active uracil salvage pathway.

25 a requirement for the Preiss-Handler NAD(+) salvage pathway.

26 important gene in the Preiss-Handler NAD(+) salvage pathway.

27 a new PET probe for the deoxyribonucleotide salvage pathway.

28 hase LASS 5, demonstrating the action of the salvage pathway.

29 that AtNIC1 participates in a yeast-type NAD salvage pathway.

30 parasites due to the absence of a pyrimidine salvage pathway.

31 on of protein transport through a nucleoside salvage pathway.

32 n of rP nucleotide formation by a nucleotide salvage pathway.

33 nitial phosphorylation step in the thymidine salvage pathway.

34 tate (PMA) produced ceramide formed from the salvage pathway.

35 ose analog into glycoproteins via the fucose salvage pathway.

36 enzymes involved in the pyridoxal phosphate salvage pathway.

37 Thus, C. elegans lacks a functional fucose salvage pathway.

38 important role in the pyridoxal 5' phosphate salvage pathway.

39 amotoi had purA and purB genes of the purine salvage pathway.

40 oxygenases are key enzymes in the methionine salvage pathway.

41 to compensate by increasing flux through the salvage pathway.

42 prevalent metabolite in the bacterial purine salvage pathway.

43 ls to activate human PXR or induce the CYP3A-salvage pathway.

44 ochondrial enzyme of the deoxyribonucleoside salvage pathway.

45 also an increased reliance on the pyrimidine salvage pathway.

46 ), a key enzyme in the pyrimidine nucleotide salvage pathway.

47 ce of inflammatory macrophages on the NAD(+) salvage pathway.

48 the diet, which restored fucosylation via a salvage pathway.

49 hereby sustain the stress-induced NMN/NAD(+) salvage pathway.

50 mide phosphoribosyltransferase in the NAD(+) salvage pathway.

51 CK), a key enzyme in the deoxyribonucleoside salvage pathway.

52 sphorylase (PNP) is part of the human purine salvage pathway.

53 ase (MTAP) is a key enzyme in the methionine salvage pathway.

54 ion of XPRT is key for regulating the purine salvage pathway.

55 bosyltransferase, a key enzyme in the purine salvage pathway.

56 ferase (MtHGPRT), a key enzyme of the purine salvage pathway.

57 )ation and being a constituent of the NAD(+) salvage pathway.

58 l phenotype relationship with the nucleoside salvage pathway.

59 steine, or of any compound in the methionine salvage pathway.

60 ed as a competitive substrate for the ribose salvage pathway.

61 pyrimidine nucleotides via both de novo and salvage pathways.

62 e combined action of NAD(+) biosynthesis and salvage pathways.

63 Nucleotides are synthesized from de novo and salvage pathways.

64 enesis, de novo synthesis as well as the two salvage pathways.

65 sis is regulated by both the de novo and the salvage pathways.

66 nucleobases and nucleosides with nucleotide salvage pathways.

67 host, the parasite does not have pyrimidine salvage pathways.

68 cleotide synthesis pathways predominate over salvage pathways.

69 Xdh is required for purine salvage pathways.

70 llows minimal BH4 production through the BH4 salvage pathways.

71 limiting BH4 rescue through NADPH-dependent salvage pathways.

72 salvages Cbi using both of the predicted Cbi salvaging pathways.

73 flux, the pentose phosphate pathway, and NAD salvaging pathways.

74 CTP originates from two sources: a salvage pathway and a de novo synthesis pathway that dep

75 PT is the rate-limiting enzyme of the NAD(+) salvage pathway and enhances SIRT1 activity by increasin

76 c for metabolic processes such as the NAD(+) salvage pathway and glycogen turnover.

77 e reductase (GMPR) is involved in the purine salvage pathway and is conserved throughout evolution.

78 e spirochete is the first step in the purine salvage pathway and may represent a novel therapeutic ta

79 bstrate enhancement of the purine nucleoside salvage pathway and might improve the liver pathology in

80 hese results reveal new aspects of mammalian salvage pathways and serve as a new benchmark for design

81 yamine metabolism and adenine and methionine salvage pathways and was believed to be encoded as a sin

82 EHYDROGENASE1 (XDH1), involved in the purine salvage pathway, and CYTOSOLIC THIOURIDYLASE SUBUNIT1 an

83 ch point between the de novo pathway and the salvage pathway, and has been shown to be a rate-limitin

84 ferase (HPRT1) is a key enzyme in the purine salvage pathway, and mutations in HPRT1 cause Lesch-Nyha

85 in vitro, that each enzyme in the hexosamine salvage pathway, and the enzymes that affect this dynami

86 hway of regulated formation of ceramide, the salvage pathway, and they define a role for this pathway

87 pen up new avenues of research in nucleoside salvage pathways, and enhance our understanding of the p

88 Moreover, the aerobic and anaerobic sulfur salvage pathways appear to be differentially controlled,

89 Homologues for enzymes involved in a fucose salvage pathway are apparently absent in the P. falcipar

90 fectious cycle, as key enzymes in the purine salvage pathway are essential for the ability of the spi

91 Two key enzymes in purine salvage pathways are IMP dehydrogenase (GuaB) and GMP sy

92 In addition, sulfur salvage pathways are necessary to ensure that key sulfur

93 Our work highlights pabA and the pyrimidine salvage pathway as potential targets for novel therapeut

94 he activation of caspase-7, and identify the salvage pathway as the critical mechanism of ceramide ge

95 and requires an intact mitochondrial NAD(+) salvage pathway as well as the mitochondrial NAD(+)-depe

96 versal pathways) and variable (recycling and salvage pathways) aspects of this subsystem.

97 ion of xanthine dehydrogenase affects purine salvaging pathways at the onset of development, creating

98 gly, fumonisin B1 (FB1), an inhibitor of the salvage pathway, attenuated loss of phosphorylation of p

99 s extend current knowledge of the nucleotide salvage pathway by revealing the metabolism of oxidized

100 e catalyzes the first step in the nucleotide salvage pathway by transferring a phosphate group to a t

101 (ATR) reduces the output of both de novo and salvage pathways by regulating the activity of their res

102 egulates ceramide metabolism mainly from the salvage pathway, by positively regulating the expression

103 Here, we show that the hexosamine salvage pathway can convert GlcNGc to UDP-GlcNGc, which

104 al component of the mitochondrial nucleotide salvage pathway, can give rise to mitochondrial DNA (mtD

105 hich catalyzes the first step of this NAD(+) salvage pathway, cannot mate due to a spicule muscle def

106 duct, mammalian cells have evolved an NAD(+) salvage pathway capable of resynthesizing NAD(+) from ni

107 However, another NAD(+) salvage pathway component, Pnc1, modulates silencing ind

108 The addition of the penultimate salvage pathway compound 4-methylthio-2-oxobutanoic acid

109 purine auxotroph possessing a unique purine salvage pathway consisting of a bacterial type purine nu

110 The nicotinamide salvage pathway, constituted by nicotinamide mononucleot

111 by UPRT, and that both the biosynthetic and salvage pathways contribute to a robust infection of the

112 Additionally, the two nicotinamide riboside salvage pathways contribute to NAD(+) metabolism in the

113 A combination of de novo and salvage pathways contribute to the biosynthesis of NAD i

114 C. glabrata salvage pathways defined in this article allow NAD(+) to

115 reduced expression of a putative methionine salvage pathway dehydratase, apoptotic protease activati

116 d nicotinamide riboside (NR) in the amidated salvage pathway despite no increase in nicotinamide phos

117 Here we show that enzymes of the nucleotide salvage pathway display substrate selectivity, effective

118 osphatiylserine decarboxylation, a potential salvage pathway, does not appear to be active in culture

119 tes of de novo dTMP synthesis, and increased salvage pathway dTMP biosynthesis relative to control fi

120 ed flux through the amidated arm of the NAD+ salvage pathway due to reduced sirtuin activity.

121 owth in a mouse, proving that the functional salvage pathway enables nicotinamide acquisition by the

122 wide search allows us to identify the NAD(+) salvage pathway encoded by an operon of nadR-pnuC-nrtR (

123 onent of the mitochondrial purine nucleotide salvage pathway, encoded by the nuclear gene encoding de

124 , but mutants lacking the (redundant) purine salvage pathway enzyme adenosine kinase are susceptible

125 mtp53 creates a dependency on the nucleoside salvage pathway enzyme deoxycytidine kinase for the main

126 rosarcoma cell line and study how methionine salvage pathway enzyme methylthioadenosine phosphorylase

127 ch is then used as a substrate by the NAD(+) salvage pathway enzyme NA phosphoribosyltransferase (Npt

128 Finally, alterations in the NAD salvage pathway enzyme nicotinamide phosphoribosyltransf

129 h FK866, a selective inhibitor of the NAD(+) salvage pathway enzyme nicotinamide phosphoribosyltransf

130 sitive to selective inhibition of the NAD(+) salvage pathway enzyme nicotinamide phosphoribosyltransf

131 wered NAD+ levels by downregulating the NAD+ salvage pathway enzyme nicotinate phosphoribosyltransfer

132 phoribosyltransferase (UPRT) is a pyrimidine salvage pathway enzyme that catalyzes the conversion of

133 opment, one is adenosine deaminase--a purine salvage pathway enzyme, and the last is a phosphatase, C

134 n wt strains and in strains lacking key NAD+ salvage pathway enzymes (PNC1 and NPT1).

135 rthermore, we revealed that both de novo and salvage pathway enzymes contribute to viral DNA replicat

136 Two phosphoribosyltransferases in the purine salvage pathway exhibit exquisite substrate specificity

137 ear ribonucleoprotein (hnRNP) A1 regulates a salvage pathway facilitating internal ribosome entry sit

138 stablishes a bifunctional oxygen-independent salvage pathway for 5'-deoxyadenosine and 5'-methylthioa

139 smodium falciparum (Pf) relies solely on the salvage pathway for its purine nucleotide requirements,

140 endent crosstalk between the proteins in the salvage pathway for NAD(+) biosynthesis and the proteaso

141 ctedly, overexpression of other genes in the salvage pathway for NAD(+) biosynthesis, including QNS1,

142 oes not require the presence of a functional salvage pathway for NAD(+) biosynthesis, SIR2 or an acti

143 S)-mediated cap-independent translation is a salvage pathway for protein expression when mTOR is inhi

144 kinase activity and up-regulates cers2b as a salvage pathway for sphingosine turnover.

145 PRT highly are entirely dependent on the NAD salvage pathway for survival.

146 yme, GalNAc kinase, has been implicated in a salvage pathway for the reutilization of free GalNAc der

147 encing and is dependent upon the de novo and salvage pathways for NAD(+) synthesis but is not correla

148 mutants, which are defective in de novo and salvage pathways for NAD(+) synthesis, respectively.

149 Recent genetic evidence reveals additional salvage pathways for NAD(+) synthesis.

150 S1) transporters are essential components of salvage pathways for nucleobases and related metabolites

151 The data are consistent with a salvaging pathway for cobinamide in which an amidohydrol

152 m glucose, just before intersection with the salvage pathway from free mannose.

153 ack loop to limit autophagy and prevent this salvage pathway from inducing RIPK1-dependent necroptoti

154 T) is the rate-limiting enzyme in the NAD(+) salvage pathway from nicotinamide.

155 AMPT), catalyzing the first reaction in the "salvage" pathway from nicotinamide, showed potent antitu

156 ed to be dispensable when the nondeamidating salvage pathway functioned as the only route of NAD biog

157 Mutations in putative salvage pathway genes downstream of MTAP also cause elev

158 thway genes revealed an up-regulation of the salvage pathway genes in vivo and in vitro under conditi

159 Bordetella parapertussis have the recycling/salvage pathway genes pncA and pncB, for use of nicotina

160 external stimuli and expansion of nucleoside salvage pathway genes potentially for competition with M

161 alysis of the de novo synthesis and putative salvage pathway genes revealed an up-regulation of the s

162 ificant increases in expression of the known salvage pathway genes, PDX3 and SOS4.

163 creased expression was more dramatic for the salvage pathway genes.

164 containing both exogenous components of the salvage pathway, GlcNAc transporter NGT1 from Candida al

165 MPT), the rate-limiting enzyme of the NAD(+) salvage pathway, governs the proinflammatory SASP indepe

166 in genes which encode enzymes in the purine salvage pathway have long been recognized as rare causes

167 novo has been extensively characterized, the salvage pathways have received comparatively little atte

168 monstrates a so far unknown phosphoglycolate salvage pathway, highlighting important diversity in mic

169 is an important component of the nucleotide salvage pathway in apicomplexan parasites and a potentia

170 ur results suggest that enhancing the NAD(+) salvage pathway in astrocytes could be a potential thera

171 ase to the mitochondria also enhances NAD(+) salvage pathway in astrocytes.

172 Thus, there is an active sphingolipid salvage pathway in both neurons and oligodendrocytes.

173 ependent regulation of the trpRBA tryptophan salvage pathway in C. trachomatis.

174 These results demonstrate a role for the salvage pathway in feedback inhibition of p38.

175 ts confirmed the presence of a robust purine salvage pathway in H. pylori.

176 es are likely to be active in the nucleotide salvage pathway in human cells, suggesting new designs f

177 sumption products (i.e., nicotinamide) via a salvage pathway in order to maintain NAD(+) homeostasis.

178 t of a pyridoxal reductase in the vitamin B6 salvage pathway in plants.

179 fy a novel role for CerS and the sphingosine salvage pathway in regulating membrane permeability in t

180 iled comparative genomic study of the purine salvage pathway in various apicomplexan species highligh

181 e 1-phosphate (DK-MTP 1-P) in the methionine salvage pathway in which 5-methylthio-d-ribose (MTR) der

182 The pathways and enzymes of the NAD salvage pathway in yeast and animals, which diverge at n

183 egies to reconstitute an efficient thymidine salvage pathway in yeast.

184 tion of hydroxylbenzoates, and the thymidine salvage pathways in certain organisms.

185 ion of the interplay between the de novo and salvage pathways in DNA synthesis with respect to enviro

186 nally, the redundancy of functional upstream salvage pathways in GAS species narrows the choice of po

187 g and a targetable molecule driving nutrient salvage pathways in PDAC and validates oncogene-driven s

188 e is known about the NAD(+) biosynthesis and salvage pathways in the opportunistic pathogen Streptoco

189 lase" reaction in the well-known "methionine salvage" pathway in Bacillus sp. and (2) the 5-methylthi

190 e environment, suggesting the existence of a salvaging pathway in this archaeon.

191 fic alterations in both the NAD+ de novo and salvage pathways including striking accumulations of nic

192 tfkgp mutant that is defective in the fucose salvage pathway indicates that 2F-Fuc must be converted

193 hrough the N-acetyl-D-galactosamine (GalNAc) salvage pathway induced abrogation of MAL-II and PNA epi

194 methyl)-2-methylpyrimidine (FAMP), a thiamin salvage pathway intermediate, into cells.

195 e role of NAD(+) metabolites/derivatives and salvage pathway intermediates as activators, inhibitors,

196 We introduced an exogenous GlcNAc salvage pathway into yeast, allowing cells to metabolize

197 -dependent stimulation of an IFN-independent salvage pathway involving IRF1 and IRF3.

198 tate) induces ceramide formation through the salvage pathway involving, in part, acid beta-glucosidas

199 Therefore, interference with the purine salvage pathway is an attractive therapeutic target.

200 , taken together, suggest that the thymidine salvage pathway is compartmentalized so that TMP kinase

201 or and cytosine, suggest that the nucleotide salvage pathway is essential for E. chaffeensis replicat

202 ion of the de novo pathway compared with the salvage pathway is not fully understood.

203 novo purine biosynthesis; hence, the purine salvage pathway is of potential therapeutic interest.

204 The purine salvage pathway is redundant and contains two routes to

205 An active NAD(+) salvage pathway is required for optimal function of each

206 ique feature of the Toxoplasma gondii purine salvage pathway is the expression of two isoforms of the

207 NTP production can be compensated for by the salvage pathway is unknown.

208 me in the cytosolic deoxyribonucleoside (dN) salvage pathway, is an important therapeutic and positro

209 (MTAP), the initial enzyme in the methionine salvage pathway, is deleted in a variety of human tumors

210 tical enzyme in the mitochondrial pyrimidine salvage pathway, is essential for mitochondrial DNA (mtD

211 itional because PA can be shuttled through a salvage pathway (Kennedy pathway) by adding choline to t

212 zes an off-pathway shunt from the methionine salvage pathway leading to the production of formate, me

213 ing the stringent response to promote purine salvage pathways, maintain GTP homeostasis and ensure co

214 This CI salvage pathway maintains highly functional CI through a

215 firms that enzymes common to the de novo and salvage pathways may be good drug targets.

216 thesis enzyme dihydrofolate reductase (DHFR, salvage pathway) mRNA levels showed a significant (P <0.

217 uctone dioxygenase (ARD) from the methionine salvage pathway (MSP) is a unique enzyme that exhibits d

218 ion as tautomerases/enolases in a methionine salvage pathway (MSP).

219 organisms possess the "universal" methionine salvage pathway (MSP).

220 we report the identification of yeast purine salvage pathway mutants that are synthetically lethal wi

221 ucleotide deficiency, RS, and the nucleoside salvage pathway (NSP) enzymes deoxycytidine kinase (dCK)

222 de novo pathway (DNP) and by the nucleoside salvage pathway (NSP).

223 is down-regulated by LPS and functions as a salvage pathway of anandamide synthesis when the PLC/pho

224 The purine salvage pathway of Anopheles gambiae, a mosquito that tr

225 ponse to PMA revealed that PMA activated the salvage pathway of ceramide formation and not the de nov

226 ation of protein kinase C (PKC) promotes the salvage pathway of ceramide formation, and acid sphingom

227 gomyelin and glucosylceramide leading to the salvage pathway of ceramide formation.

228 n conjunction with tracers for the thymidine salvage pathway of DNA synthesis, because thymidine cont

229 midase (PNC), the first enzyme in the NAD(+) salvage pathway of invertebrates.

230 oxygenase (ARD) isozymes from the methionine salvage pathway of Klebsiella ATCC 8724 present an unusu

231 Unlike many components of the purine salvage pathway of L. donovani, both ASL and ADSS are cy

232 yrazinamidase (PncA) is involved in the NAD+ salvage pathway of Mycobacterium tuberculosis and other

233 ribosyltransferase involved in the mammalian salvage pathway of NAD synthesis.

234 ene encoding the rate-limiting enzyme in the salvage pathway of NAD(+) biosynthesis.

235 ase (NAMPT) is a rate-limiting enzyme in the salvage pathway of nicotinamide adenine dinucleotide bio

236 This enzyme is important in the salvage pathway of nucleoside recycling.

237 on to fcy2Delta and hpt1Delta mutants in the salvage pathway of purine nucleotide biosynthesis, mutan

238 ly, are the only known genes involved in the salvage pathway of pyridoxal 5'-phosphate in plants.

239 The salvage pathway of the bovine tubercle bacillus Mycobact

240 assess the relative roles of the de novo and salvage pathways of GDP-mannose biosynthesis.

241 e analogs to capitalize on the highly active salvage pathways of Leishmania, which are purine auxotro

242 an intrinsic mRNA-specific protein synthesis salvage pathway operative in glioblastoma (GBM) tumor ce

243 generation of NAD(+) from nicotinamide via a salvage pathway or by de novo synthesis of NAD(+) from t

244 in noncycling cells, are generated either by salvage pathways or through de novo synthesis.

245 rse metabolic pathways, including the uracil salvage pathway, oscillate in a circadian fashion and in

246 conditions, suggesting that the dual-purpose salvage pathway plays a central role in numerous environ

247 Gpd1p as well as a key enzyme of the NAD(+) salvage pathway, Pnc1p; (ii) Pnc1p, a nicotinamidase wit

248 We discovered and characterized 2 Q salvage pathways present in many pathogenic and commensa

249 ad development results from depletion of the salvage pathway product NAD(+), whereas the uv1 cell nec

250 l regulatory pathway in which the methionine salvage pathway products inhibit ODC activity.

251 The NAD(+) salvage pathway protein, Npt1, regulates Sir2-mediated p

252 One of the pivotal enzymes in its purine salvage pathway, purine nucleoside phosphorylase (PNP),

253 e pool of ceramide involved derives from the salvage pathway rather than de novo biosynthesis.

254 The methionine salvage pathway recycles one-carbon units lost to polyam

255 results show that products of the methionine salvage pathway regulate polyamine biosynthesis and sugg

256 +) biosynthesis genes while the genes in the salvage pathway remain unaffected.

257 compensatory activation of the sphingolipid salvage pathway, resulting in significant accumulation o

258 a formed from the protein kinase C-dependent salvage pathway results at least in part from the action

259 s mainly synthesized in human cells via the "salvage" pathways starting from nicotinamide, nicotinic

260 subunit proteins of the Calvin cycle and AMP salvage pathways suggests a strong biological role in hi

261 f glutaminolysis and triggers autophagy as a salvage pathway supporting leukemia cell metabolism.

262 n of NAD(+) levels by stimulating the NAD(+) salvage pathway suppressed mitochondrial protein hyperac

263 istance in Leishmania spp., as it provides a salvage pathway that bypasses dihydrofolate reductase (D

264 This defines a critical salvage pathway that can be autoinduced to minimize trio

265 enase (Fe-ARD'), an enzyme in the methionine salvage pathway that catalyzes the regiospecific oxidati

266 transferase, the rate-limiting enzyme in the salvage pathway that converts nicotinamide to NAD (mNAMP

267 It is part of the purine salvage pathway that has been identified only in eukaryo

268 oxidase (PDX3), have been identified in the salvage pathway that interconverts between the six vitam

269 nce of Cryptosporidium parasites on a single salvage pathway that leads to essential purine derivativ

270 and plants, most higher organisms rely on a salvage pathway that phosphorylates either pyridoxal (PL

271 atal Fc receptor, FcRn mediates an endocytic salvage pathway that prevents degradation of IgG, thus c

272 NAM is an intermediate in the NAD salvage pathway that should accumulate in nicotinamidase

273 occurs either de novo or through one of the salvage pathways that converge at the point where the re

274 phorylase (UP) is a key enzyme of pyrimidine salvage pathways that enables the recycling of endogenou

275 NAD+ metabolism in the de novo, import, and salvage pathways that originate from tryptophan (or aspa

276 an biosynthesize PLP de novo, they also have salvage pathways that serve to interconvert the differen

277 rresponding UDP sugar-donor by the canonical salvage-pathway that requires phosphorylation at the 6-h

278 lization, polyamine biosynthesis, the purine salvage pathway, the methionine salvage pathway, the SAM

279 , the purine salvage pathway, the methionine salvage pathway, the SAM radical pathways, autoinducer-2

280 ctionally address the role of the pyrimidine salvage pathway, the uridine phosphorylase (UP) salvage

281 s, and extend the function of the Rad1/Rad10 salvage pathway to 3'-phosphates.

282 we probe the contribution of the NAM-NAD(+) salvage pathway to muscle development and function using

283 pyridoxal kinase (PDXK) acts in vitamin B(6) salvage pathway to produce pyridoxal 5'-phosphate (PLP),

284 pression of multiple NAD(+) biosynthesis and salvage pathways to promote homeostasis during stationar

285 To characterize the uridine salvage pathway, two genes, UKL1 and UKL2, that tentativ

286 Following the GalNAc salvage pathway, UDP-GalNGc is epimerized to UDP-GlcNGc,

287 mor proliferation as a function of thymidine salvage pathway utilization.

288 From these latter CDSs, an NAD salvage pathway was inferred that appears to be unique a

289 the bacterium Salmonella enterica, whose Cbi-salvaging pathway was blocked.

290 volved in the hydroxymethyl pyrimidine (HMP) salvage pathway, was solved by the multiwavelength anoma

291 s depleted and metabolites of the deamidated salvage pathway were reduced but intracellular NAD+ and

292 ammalian cells is synthesized via the NAD(+) salvage pathway, where nicotinamide phosphoribosyltransf

293 MT tumors preferentially used the nucleotide salvage pathway, whereas papillary tumors preferred de n

294 inase (TK) is a key enzyme in the pyrimidine salvage pathway which catalyzes the transfer of the gamm

295 rase 1 (NMNAT-1) constitute a nuclear NAD(+) salvage pathway which regulates the functions of NAD(+)-

296 (NAMPT), the rate-limiting enzyme in the NAD salvage pathway, which acts as negative regulator of the

297 , one of the major enzymes of the nucleoside salvage pathway, which affects peripheral T cell homeost

298 Part of this effect was mediated by the NR salvage pathways, which generate NAM as a product and re

299 that supplementation of BH4 (via the pterin salvage pathway with Sep) increased Akt/eNOS phosphoryla

300 the rate-determining step in the nucleoside salvage pathway within all domains of life where the pat