ライフサイエンスコーパス: saponin

1 first permeabilized the viral membrane with saponin.

2 rachomatis-infected cells permeabilized with saponin.

3 asion (MMP-9) were also downregulated by the saponin.

4 rol-specific probes, cholesterol oxidase and saponin.

5 SR Ca2+ load in myocytes permeabilized with saponin.

6 over- or under-estimate levels of steroidal saponins.

7 gly increased the accumulation of triterpene saponins.

8 etermine the bitter impact of the individual saponins.

9 lgaris is the only crucifer known to produce saponins.

10 chemicals and provides specific detection of saponins.

11 other, susceptible plants produce different saponins.

12 ed SE and particular plant glycosides called saponins.

13 nd evaluation of chemically stable synthetic saponins.

14 ust calibrations were obtained for the total saponins.

15 traction yield and bioaccessibility of total saponins.

16 ed or not with fibers, phytates, tannins and saponins.

17 her comparative peak responses for steroidal saponins.

18 ts about sapogenins, the hydrolyzed forms of saponins.

19 driving force of the metabolic evolution of saponins.

20 erivatives of Quillaja saponaria (QS) Molina saponins.

21 rofiles from their respective natural parent saponins.

22 saponins, to quantify the group of steroidal saponins.

23 ounds (1.8-fold), total flavonoids (3-fold), saponins (1.8-fold) and antioxidant capacity (37%).

24 on mass measurements among these 44 detected saponins 10 groups of isomers were identified.

25 able to annotate 52 metabolites including 8 saponins, 10 flavonoids, 6 phenolics, 10 alkaloids, and

26 approximately 0.2%), oxalate (2.2-3.4%) and saponin (2.6-3.0%) contents were fairly high; phytate co

27 rophyll (321%), condensed tannins (278%) and saponins (211%) in the concentrated mate extract.

28 iculatum led to the isolation of the two new saponins (22R, 23S, 25R)-3beta, 6alpha, 23-trihydroxy-5a

29 QS-7 increased adjuvant activity and led to saponin 3's similar IgG1 and IgG2a activities to QS-21's

30 Interestingly, the monodesmosidic saponins 5a/b were demonstrated for the first time to be

31 different B. vulgaris organs correlates with saponin abundance.

32 eed-specific transcription factor TRITERPENE SAPONIN ACTIVATION REGULATOR3 (TSAR3), which controls he

33 1 is a defined, highly purified, and soluble saponin adjuvant currently used in licensed and explorat

34 ntrol GPI-0100, a well-studied semisynthetic saponin adjuvant mixture derived from Quillaja saponaria

35 nd fucoside to mimic the naturally occurring saponin adjuvant QS-7.

36 oligosaccharide domain together orchestrate saponin adjuvant's potentiation of immune responses.

37 or within the tetrasaccharide eliminated the saponins' adjuvant activity in terms of IgG production.

38 re a viable natural source to provide potent saponin adjuvants after simple chemical derivatization a

39 The semisynthetic saponin adjuvants have shown significantly different imm

40 interactions of triterpenoid monodesmosidic saponins, alpha-hederin and delta-hederin, with lipid me

41 QS-21 as part of a heterogeneous mixture of saponins also induced IL-1beta in an NLRP3-dependent man

42 cause a decline in the TEER value, but only saponin alters the capacitance of the cell layer by two

43 Saponins, an important group of bioactive plant natural

44 d a number of Quillaja saponaria Molina (QS) saponin analogues with a different C28 sugar unit, which

45 aration of otherwise unattainable nonnatural saponin analogues.

46 ion of cholesterol with cholesterol oxidase, saponin and cyclodextrin, presumably by displacing chole

47 membrane (PPM) to the amphipathic glycoside saponin and engenders digestive vacuoles (DVs) that are

48 nd sterols and on the molecular shape of the saponin and its ability to induce local spontaneous curv

49 results demonstrate that the combination of saponin and phytosterols is a powerful new approach to s

50 y examined the potential of natural quillaja saponin and polyphenols (vanillin, epigallocatechin gall

51 enugreek (FE, HFE) and quinoa (QE, HQE), and saponin and sapogenin standards, were assessed on the in

52 chanism dependent on the interaction between saponin and sterols and on the molecular shape of the sa

53 The saponin and tannin contents of the seed were reduced by

54 s defend themselves through the induction of saponin and volatile terpenoid biosynthesis.

55 The iRBCs were lysed with a 15% solution of saponin and washed with phosphate buffered saline to rel

56 ne permeabilization of cardiac myocytes with saponin and/or Triton X-100 increased NAADP synthesis, i

57 arameters and color after adding flavonoids, saponins and anthocyanins from black bean seed coat in N

58 black beans coat is a source of flavonoids, saponins and antocyanins.

59 The yield of total saponins and bioaccessibility was 1.61 and 18.6%, respec

60 The kinetics of total saponins and bioaccessibility were investigated for the

61 mauritiana leaf specimens found enriched in saponins and distinct from that of Z. jujuba in which qu

62 punctual associations between the black bean saponins and flavonoids concentrations to the antioxidan

63 rative activity against cancer cell lines of saponins and flavonoids extracted from seed coats, cotyl

64 ESI-QTOF-MS/MS) metabolite profiling data of saponins and glycosylated flavonoids from the model legu

65 prediction of plant natural products such as saponins and glycosylated flavonoids through combinatori

66 tation of the toxicity of targeted toxins by saponins and indicated the superiority of real time moni

67 ommended for increasing the concentration of saponins and non-glycosylated flavonols in sprouts and s

68 synthesizes two types of saponins, hemolytic saponins and nonhemolytic soyasaponins, which accumulate

69 The identified phenolic acids, saponins and other as yet unidentified compounds may con

70 Moreover, the effect of pearling process on saponins and phenolic content in quinoa were evaluated.

71 As expected, whole quinoa had the highest saponins and phenolics contents.

72 dology was used to identify and quantify the saponins and reversed phase-high performance liquid chro

73 or differences in the molecular shape of the saponins and the effects on membrane curvature that shou

74 time that 18 saponins with dioxolane-type (2 saponins) and acetal-type (16 saponins) substituents wer

75 ether)-N,N,N',N'-tetraacetic acid (EGTA) and saponin, and (c) sonoporation.

76 e protein synthesis inhibitor cycloheximide, saponin, and Pseudomonas exotoxin A additionally confirm

77 ers, accumulation of a variety of triterpene saponins, and extensive but differential ectopic express

78 es, a new dimeric phenylpropanoid glucoside, saponins, and fatty acids were identified online, or aft

79 is rich in phytochemicals like polyphenols, saponins, and steroidal glycosides, but its crop is grea

80 Saponins appeared as white spots against a pink backgrou

81 Saponins are a class of natural compounds present in pul

82 Saponins are a specific class of defense compounds compr

83 These results confirm that Momordica saponins are a viable natural source to provide potent s

84 Triterpenoid saponins are bioactive metabolites that have evolved rec

85 Quinoa surface borne saponins are bitter tasting anti-nutritional compounds t

86 ng that the unique adjuvant activities of QS saponins are determined by their specific structures.

87 Antimicrobial saponins are first hydrolysed by a fungal saponin-detoxi

88 Triterpene saponins are important bioactive constituents with an en

89 Saponins are known for their bioactive and surfactant pr

90 Saponins are promising compounds for ameliorating hyperl

91 opherol acetate were prepared using quillaja saponin as a natural surfactant, and either long chain t

92 ombined ultrasound and enzyme pretreatments, saponin as a natural surfactant, and glycerol as a co-su

93 n-enriched emulsions prepared using quillaja saponin as an emulsifier and ascorbic acid as an antioxi

94 he active encapsulation techniques, with the saponin-assisted method in particular, allowed an up to

95 runcatula synthesizes more than 30 different saponins based on at least five triterpene aglycones; so

96 CpG-C together with the clinically relevant saponin-based adjuvant AbISCO-100/Matrix-M (AbISCO), to

97 terial LRI diagnosis that features efficient saponin-based host DNA depletion and nanopore sequencing

98 t of a new series of structurally defined QS-saponin-based synthetic adjuvants.

99 We have prepared a number of saponin-based vaccine adjuvant candidates.

100 med that it is a feasible way to develop new saponin-based vaccine adjuvants through derivatizing at

101 nanoemulsions were formulated using Quillaja Saponin bio-surfactant and green solvents including high

102 he basic helix-loop-helix family, TRITERPENE SAPONIN BIOSYNTHESIS ACTIVATING REGULATOR1 (TSAR1) and T

103 d, the final oxidation step of the hemolytic saponin biosynthesis branch in M. truncatula In addition

104 This appears to be a common theme among saponin biosynthesis genes, especially glycosyltransfera

105 REGULATOR3 (TSAR3), which controls hemolytic saponin biosynthesis in developing M. truncatula seeds.

106 1 (TSAR1) and TSAR2, which direct triterpene saponin biosynthesis in Medicago truncatula.

107 P450 and glycosyltransferases in triterpene saponin biosynthesis in Medicago.

108 ncluding isoflavonoid, lignin and triterpene saponin biosynthesis were modified or added based upon a

109 verexpression specifically boosted hemolytic saponin biosynthesis, whereas TSAR1 overexpression prima

110 t types is determined at an earlier stage in saponin biosynthesis.

111 confirmed the in vivo function of UGT73F3 in saponin biosynthesis.

112 evated transcript levels of known triterpene saponin biosynthetic genes and strongly increased the ac

113 of transactivation of downstream triterpene saponin biosynthetic genes, hinting at distinct function

114 e range 0.05 to 0.15 mg.ml(-1) (0.05 - 0.15% saponin by weight of seed).

115 Analysis of saponins by thin layer chromatography (TLC) is reported.

116 se results prove that derivatizing Momordica saponins can be a viable way for easy access to structur

117 vivo evidence that one compound of diosgenyl saponins can be potential treatment for AP.

118 ng flavonoids, phenolic acids, anthocyanins, saponins, carotenoids, terpenes, sugars, proteins, capsa

119 Circular dichroism shows that saponin changes the beta-galactosidase secondary structu

120 PLC studies further confirmed the absence of saponins (characteristic toxins present in MC) in both f

121 Sprouts had a higher concentration of saponins compared to cotyledons or seed coats (p<0.05).

122 lyzed by HPLC for total isoflavone and total saponin composition, as well as total carbohydrate compo

123 After the first day of germination, the saponin concentration in sprouts and cotyledons increase

124 Results demonstrated that saponin concentration may be measured in the range 0.05

125 ors an accurate inexpensive way of measuring saponin concentration to satisfy current seed quality sp

126 The saponins concentration in hilum increased 2.3-fold after

127 IC(50) value significantly correlated to the saponin content (r = -0.82; p = 0.001).

128 The total saponin content and its in vitro bioaccessibilities in T

129 ative method was developed that can quantify saponin content in aqueous solutions with greater accura

130 henolic compounds, antioxidant capacity, and saponin content in quinoa grains were evaluated.

131 cessary to obtain sweet quinoa (with a total saponin content lower than 110 mg/100 g).

132 Saponin content of the water extracts was in the range o

133 The method applied satisfactorily to saponin content up to 0.2 mg.ml(-1) as higher concentrat

134 capacity, DPPH scavenging activity and total saponin content were inhibited after the concentration o

135 educing power, total iridoids content, total saponin content, and total phenolic content in treated p

136 To determine saponin content, the currently available standard afrosi

137 l phenolic content, phenolic composition and saponin content.

138 cooking, and/or germination, particularly on saponins content.

139 values, also to reduce phytate, oxalate and saponin contents, simultaneously enhanced the nutritiona

140 evated level of an active fungicidal form of saponin, dAA in the husks possibly indicates they are mo

141 r the early steps in avenacin A-1 synthesis [saponin-deficient 1 and 2 (Sad1 and Sad2)] have been rec

142 cytochromes P450, AsCyp51H10 (also known as Saponin-deficient 2, Sad2), that is required for avenaci

143 The increase in the enzyme activity by saponins, demonstrated here, is important to new product

144 al saponins are first hydrolysed by a fungal saponin-detoxifying enzyme.

145 juvant active of these fluorescently labeled saponins does not simply associate with the plasma membr

146 This work evaluated the saponins effects on Kluyveromyces lactis beta-galactosid

147 Permeabilizing the myocytes with saponin eliminated differences between spontaneous spark

148 ovided specific detection of saponins in the saponins enriched extracts from Aesculusindica (Wall. ex

149 vergent synthetic preparation of these novel saponins establishes new avenues for discovering improve

150 s for the antioxidant properties of Quillaja saponin extract and their presence at the interface faci

151 Quillaja saponin extract comprises both, surfactants and phenolic

152 vestigate the antioxidant effect of Quillaja saponin extract in oil/water emulsions.

153 Antioxidant efficiency of the saponin extract was determined photometrically by 2,2'-d

154 O-in-W) stabilized by Yucca Schidigera Roezl saponin extract, is by >50 times higher as compared to t

155 Diosgenyl saponins extracted from natural products and diosgenin o

156 passive and active methods (electroporation, saponin, extrusion and dialysis).

157 t, two other adjuvants, imiquimod and Quil A saponin, favored an expansion of antigen-specific Tregs

158 HPLC/ELSD methods yield a saponin fingerprints specific to the plant species.

159 Among 10 compounds identified (saponins, flavonoids and sterols) five were reported for

160 umerous phytochemicals including terpenoids, saponins, flavonoids, alkaloids.

161 otate specific compounds, such as alkaloids, saponins, flavonoids, and terpenoids, which are most lik

162 Saponins, flavonols and isoflavones were quantified in s

163 production of anti-nutritional triterpenoid saponins found in quinoa seeds, including a mutation tha

164 024.7 g kg(-1) from WS supplemented with 20% saponin free detoxified mahua cake.

165 s along with production of nutrient rich and saponin free fruit bodies/spent.

166 n at room temperature, permeabilization with saponin, freeze-thaw cycles, sonication, or extrusion.

167 Avicins, a family of triterpenoid saponins from Acacia victoriae, can regulate the innate

168 family of natural plant-derived triterpenoid saponins from Acacia victoriae, mislocalizes K-Ras from

169 The ultrasonic-assisted extraction of total saponins from alfalfa leaves was optimised by the simult

170 p to 6 times higher than the daily intake of saponins from beans by vegetarians.

171 Flavonoids and saponins from common beans have been widely studied due

172 owever, the therapeutic effects of diosgenyl saponins from Dioscorea zingiberensis C. H. Wright in AP

173 Processing and cooking promotes the loss of saponins from foods.

174 nvestigate the micelle-forming properties of saponins from Quillaja saponaria Mollina (QS) in order t

175 results reveal for the first time, steroidal saponins from S. paniculatum and the antiulcer effect of

176 Here, we profiled triterpene saponins from the skin and flesh of red beetroot Beta vu

177 ytosterols from the non-purified oil and the saponins from the Yucca extract lead to the formation of

178 sessed the non-toxic doses of the triterpene saponins (ginsenoside-Rb3 and ginsenoside-Rd) - as prebi

179 fragmentation patterns between the isolated saponin glycoside at m/z 1445.64 [M + formic-H](-) equiv

180 lted in the isolation of a norlanostane-type saponin glycoside with antitrypanosomal activity of 98.9

181 In addition, several triterpenoid saponin glycosides accumulated in M. truncatula upon ino

182 ar weight compounds, which were matched with saponin glycosides, while triterpenoids and steroids occ

183 l-sn-glycero-3-phosphocholine (DMPC) and the saponin glycyrrhizin in the presence of sucrose.

184 These unnatural saponins have a different terminal-functionalized side c

185 Yucca GRAS-labelled saponins have been and are increasingly used in food/fee

186 Saponins have plasma cholesterol lowering effect in huma

187 Medicago truncatula synthesizes two types of saponins, hemolytic saponins and nonhemolytic soyasaponi

188 (KLH) and Tn(c)-palmitic acid (PAM) with the saponin immunologic adjuvant QS21, in a phase I clinical

189 s to a convergent construction of the potent saponin immunostimulant.

190 way for easy access to structurally defined saponin immunostimulants with favorable adjvuant activit

191 reshold factors to be the predominant bitter saponin in raw asparagus spears, 3-O-[alpha-L-rhamnopyra

192 The role of phenolics and saponins in contributing to bitterness in marama beans,

193 ion of bitter-tasting mono- and bidesmosidic saponins in fresh and processed asparagus (Asparagus off

194 king on the stability and bioavailability of saponins in pulses is an important area which should be

195 The protocol provided specific detection of saponins in the saponins enriched extracts from Aesculus

196 onstituted the synthesis of monoglycosylated saponins in yeast.

197 14.7-88.9% by BSW and 14.5-87.3% by BNW) but saponin increased in 18 vegetables by BNW while 8 vegeta

198 permeabilization of neuroblastoma cells with saponin increased InsP3 sensitivity of Ca2+ release, ind

199 Depletion of human DNA with saponin increased N. gonorrhoeae yields in simulated inf

200 itration calorimetry analyses suggested that saponins increased the affinity of beta-galactosidase wi

201 e CNBH as flavans declined with nitrogen but saponins increased.

202 221 were only detected after treatment with saponin, indicating the intracellular localizations of l

203 T PCs, but such differences were reversed on saponin-induced membrane permeabilization, indicating th

204 Avicin D, a natural triterpenoid saponin, inhibits cell growth and induces apoptosis in t

205 Total phenols, saponins, iridoids and total antioxidant content and DPP

206 the effect of processing (of pulses) on the saponins is also highlighted.

207 The biosynthesis of triterpene saponins is poorly characterized in spite of the importa

208 ffects of Notoginsenoside R1 (NTR1), a major saponin isolated from Panax notoginseng, on neuronal exc

209 xture derived from Quillaja saponaria Molina saponins, known for its ability to induce a balanced Th1

210 e use of microfluidic cell enrichment with a saponin lysis before MRR detection can overcome these ch

211 igh-throughput and cost-effective assay, the Saponin-lysis Sexual Stage Assay (SaLSSA), for identifyi

212 ed the safety and immunogenicity of a novel, saponin (Matrix-M)-adjuvanted, recombinant hemagglutinin

213 This study suggests natural saponins may serve as fruitful sources for exploring/ide

214 The loss of GFP through saponin-mediated pores was associated with a concomitant

215 n terms of morphology of lutein ester loaded saponin micelles (LMS), cryo-TEM micrographs showed depe

216 much less toxic than the widely used natural saponin mixture Quil A.

217 oped an analytical model taking into account saponin molecule diffusion, cell geometry, cytosol molec

218 creation, hinting that the diffusion of the saponin molecules to the membrane is the limiting factor

219 anine kidney cells after permeabilization by saponin molecules.

220 eir presence at the interface facilitated by saponin molecules.

221 from the Th2 immunity induced by the natural saponin MS I.

222 dates, VSA-2 (5b), a derivative of Momordica saponin (MS) II, showed consistent enhancement of immuno

223 We have derivatized Momordica saponins (MS) I and II through their coupling at C3 gluc

224 namoyl)-bet a-d-glucopyranoside (7) and four saponins, named licoricesaponins M3 (13), N2 (14), O2 (1

225 One promising adjuvant is QS-21, a saponin natural product that is the immunopotentiator of

226 nthesis of a branched pentasaccharide from a saponin natural product.

227 The saponins of the model legume Medicago truncatula are gly

228 We tentatively identified 44 triterpene saponins, of which 37 had not been detected previously i

229 tants such as antimicrobial lipopeptides and saponins, often show a superior performance to permeabil

230 Detection of saponins on the TLC plates after development and air-dry

231 emulsifier types (Tween 80, BSA and quillaja saponins) on the formation of clove oil nanoemulsion, th

232 redicted natural intense sweeteners comprise saponin or stevioside scaffolds.

233 ing either non-detergent or detergent-based (saponin or Triton X-100) methods.

234 of radiolabelled dNTPs into mitochondria of saponin permeabilized cells.

235 were measured in perfused working hearts and saponin-permeabilized cardiac fibers, respectively.

236 nd mitochondrial function were determined in saponin-permeabilized cardiac fibers.

237 ory function and metabolism were assessed in saponin-permeabilized cardiac muscle fibers.

238 channel, we compared SR Ca(2+) transport in saponin-permeabilized cardiomyocytes before and after li

239 In saponin-permeabilized cardiomyocytes, the thiol redox st

240 scan images revealed persistent LCRs both in saponin-permeabilized cells and in spontaneously beating

241 Mitochondrial function was determined in saponin-permeabilized fibers and proton leak kinetics an

242 ial function and coupling were determined in saponin-permeabilized fibers, and proton leak kinetics w

243 In saponin-permeabilized myocytes IP(3) and the more potent

244 Fused or saponin-permeabilized pseudoviruses that partially lost

245 Ca(2+) sparks recorded in saponin-permeabilized vascular myocytes have increased f

246 ively controlled physiological conditions in saponin-permeabilized wild type (WT) and phospholamban k

247 microM (SOAT2)), while in those treated with saponin (plasma membrane and ER membrane permeabilized),

248 content of inhibitory compounds (TIC, total saponin plus phenolic) were prepared with and without co

249 Saponins possess many biological activities, including c

250 Diosgenin, a steroidal saponin present in fenugreek (Trigonella foenum graecum)

251 structures, contents and health benefits of saponins present in pulses are discussed.

252 Quillaja saponin produced emulsions with the best overall stabili

253 This suggests saponin production should be considered in terms of deta

254 As the method is capable of distinguishing saponin profiles from taxonomically distant species, it

255 increase in the protein activity due to the saponin-protein interaction.

256 -O-desacyl-4'-monophosphoryl lipid A and the saponin QS-21.

257 -O-desacyl-4'-monophosphoryl lipid A and the saponin QS-21.

258 Modified starch (MS) and Quillaja saponins (QS) were compared to fabricate and stabilize o

259 echniques presently used for Yucca steroidal saponin quantification remain either inaccurate and misl

260 specific for the biosynthesis of triterpene saponins remain uncharacterized at the molecular level.

261 25 mM generated using 1% SDS and 1% Quillaja saponin resulted in >6 log CFU/ml reduction in Salmonell

262 tion and extrusion, or permeabilization with saponin resulted in high loading efficiency, sustained r

263 Saponin-rich extracts and their hydrolysates from fenugr

264 The hydrolysis process of saponin-rich extracts enhances the bioactivity and allow

265 with different emulsifier compositions of a saponin-rich, food-grade Quillaja extract alone or combi

266 Cells are permeabilized using saponin (SAP), digitonin (DIG) or recombinant perfringol

267 Emulsions stabilised by Quillaja saponin showed decreased oxidation stability due to natu

268 d with SE in the presence and absence of the saponin SpnS-1 (isolated from Saponaria officinalis root

269 studies have yielded critical insights into saponin structure-function relationships, provided pract

270 xolane-type (2 saponins) and acetal-type (16 saponins) substituents were detected in the roots of red

271 on the presence of membrane cholesterol and saponin sugar chains, being largest for alpha-hederin an

272 d QS-21 as a nonparticulate single molecular saponin that activates the NLRP3 inflammasome, but this

273 gnificantly less toxic than QS-21, a related saponin that is currently the favored adjuvant in antica

274 QS-21 is a potent immunostimulatory saponin that is currently under clinical investigation a

275 omprise oleanane- and ursane-type triterpene saponins that are abundantly present in the roots of the

276 According to the amount of saponins, the grains were classified as bitter.

277 ctively permeabilize the plasma membrane and saponin to permeabilize all cellular membranes.

278 not require each and every pure standard of saponins, to quantify the group of steroidal saponins.

279 ing in a 4-fold increase in fluorescence for saponin treated cells.

280 rane localization of epitope-tagged hASBT in saponin-treated (permeabilized) and nonpermeabilized tra

281 In membrane-permeabilized (saponin-treated) atrial myocytes, where [Ca2+] can be ex

282 ed to production of two classes of defenses, saponins (triterpenoids) and flavans (phenolics), in Pen

283 The impact of emulsifier type (quillaja saponin, Tween 80, whey protein and casein) and antioxid

284 , in 10-microg amounts mixed with a Ribi- or saponin-type adjuvant, were administered subcutaneously

285 reatment of Chinese hamster ovary cells with saponin under carefully controlled conditions allowed en

286 test method only determines the presence of saponin via a rating of either 'acceptable' or 'unaccept

287 0, Sodium Dodecyl Sulfate (SDS) and Quillaja Saponin was evaluated against Salmonella serotypes Newpo

288 tein microenvironment due to the presence of saponin was observed by fluorescence spectroscopy.

289 -fortified emulsions prepared using quillaja saponin was therefore investigated further.

290 Specifically, saponin was used to compromise cell membranes, and a flu

291 repared using a natural surfactant (quillaja saponin) was studied using a simulated gastrointestinal

292 tly higher in oat, while avenanthramides and saponins were characteristically present in oat.

293 mmary cancer cells but flavonols and group B saponins were more related with hepatic and colon cancer

294 In addition, highest levels of total saponins were observed in chloroform extract of the Chin

295 d previously in the root of red beets and 27 saponins were tentatively identified as potentially new

296 rain, AA and AB were revealed as the primary saponins, whereas in the husks, dAA was predominant.

297 was developed to synthesize OSW-1, a natural saponin with potent antitumor activities, from (+)-dehyd

298 We report for the first time that 18 saponins with dioxolane-type (2 saponins) and acetal-typ

299 can shrub Maesa lanceolata are oleanane-type saponins with diverse biological activities.

300 Unfortunately, the interactions of these saponins with lipid membranes are largely unknown, as ar