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1 ed fatty acid fraction was higher than total saturated fatty acid.
2 d long-chain base and a C24 monohydroxylated saturated fatty acid.
3 ls to apoptosis in response to TNF alpha and saturated fatty acid.
4 n enzyme responsible for the desaturation of saturated fatty acids.
5 ere observed only in adipocytes treated with saturated fatty acids.
6 sis and promotes the hepatic accumulation of saturated fatty acids.
7 ntration of the total and certain individual saturated fatty acids.
8 lyzed for unsaturated fatty acids (UFAs) and saturated fatty acids.
9 ontained palmitic and stearic acids as major saturated fatty acids.
10 acids (n-3 and n-6), and the lower levels of saturated fatty acids.
11 ynthesis of monounsaturated fatty acids from saturated fatty acids.
12 overstimulation of the JNK1/c-Jun pathway by saturated fatty acids.
13 lum (ER) stress is elicited in beta-cells by saturated fatty acids.
14 patocyte sensitivity to cytotoxic effects of saturated fatty acids.
15 d unsaturated fatty acids for growth but not saturated fatty acids.
16 high levels of intracellular cholesterol and saturated fatty acids.
17 ceride biosynthesis increased sensitivity to saturated fatty acids.
18 egulation of fabA transcription by exogenous saturated fatty acids.
19 oprotein(a) in comparison with diets high in saturated fatty acids.
20 rimentally observed omega-1 hydroxylation of saturated fatty acids.
21 aturated fatty acids and decreased levels of saturated fatty acids.
22 ering the tolerance limits for salt, fat and saturated fatty acids.
23 e cashews exceed the disqualifying amount of saturated fatty acids.
24 id subspecies containing monounsaturated and saturated fatty acids.
25 le and beta-cells under conditions of excess saturated fatty acids.
26 ert a part of their dietary carbohydrates to saturated fatty acids.
28 s1 (fab1) mutant has increased levels of the saturated fatty acid 16:0 due to decreased activity of 3
29 s1 (fab1) mutant has increased levels of the saturated fatty acid 16:0, resulting from decreased acti
30 nce limits was observed for fat content; for saturated fatty acids, 27% of the samples were outside o
31 were 0.84 (0.77-0.92; P<0.001) for replacing saturated fatty acids, 5% of energy); 0.86 (0.82-0.91; P
33 ich in omega-3 fatty acids to a diet rich in saturated fatty acid affects the substrates for brain pl
34 y acid needs, including both unsaturated and saturated fatty acids, along with the 3-hydroxyl fatty a
35 synthetic PC species containing at least one saturated fatty acid also support the native conformatio
36 xposure of primary peritoneal macrophages to saturated fatty acids also alters iron metabolism gene e
37 ing pathway triggered by TLR4 recognition of saturated fatty acids, an event that is essential for li
38 changes in fatty acid composition (increased saturated fatty acid and decreased monounsaturated fatty
39 ntent, total phenolic acids, gamma-oryzanol, saturated fatty acid and mono-unsaturated fatty acid of
40 nd elongation of mono-, poly-unsaturated and saturated fatty acids and enabled us to delineate, and p
41 , odd-chain fatty acids, and very-long-chain saturated fatty acids and low concentrations of gamma-li
42 genic, thrombogenic and hypercholesterolemic saturated fatty acids and lower desired fatty acids), an
43 ntioxidant capacity, total phenolic content, saturated fatty acids and monounsaturated fatty acids (M
45 range of adverse dietary factors, including saturated fatty acids and some sugars, suggesting that c
46 pes of dietary fat, and food sources rich in saturated fatty acids and the incidence of type 2 diabet
47 10th and 20th days increased content of all saturated fatty acids and two of the four unsaturated fa
48 legumes, cereals, fish, monounsaturated and saturated fatty acids, and alcohol and constructed MeDi
49 ial set of fatty acids, highly enriched with saturated fatty acids, and caveolin-1 was acylated by pa
50 e; intakes of energy, trans fatty acids, and saturated fatty acids; and use of supplements, cardiovas
55 We evaluated synthetic omega-3 epoxides of saturated fatty acids as antiproliferative and pro-apopt
56 l analyses, and the data indicate long chain saturated fatty acids as the biological substrates of th
57 We found that the fraction of CD36-dependent saturated fatty acid association/absorption in these mod
58 o cultured cells by showing that exposure to saturated fatty acids at concentrations that lead to end
59 eered yeast lipid comprises EPA at 56.6% and saturated fatty acids at less than 5% by weight, which a
60 aberrant generation of bioactive lipids when saturated fatty acid availability to tissues is increase
61 higher delta(18)O, delta(2)H, linoleic acid, saturated fatty acids beta-sitosterol, sn-1 and 3 diglyc
62 in fat absorption, especially of long-chain saturated fatty acids, but pancreatic triglyceride lipas
63 st cell membrane rigidification by exogenous saturated fatty acids by regulating phospholipid composi
64 ice fed a high-fat diet, increased uptake of saturated fatty acids by the osteoblast accelerates the
66 erminal alkenes are produced from a range of saturated fatty acids (C12-C20), and stopped-flow spectr
68 , these two co-products are rich in long and saturated fatty acids (C22:0-C24:0), contain cholesterol
69 idence that palmitic acid, the major dietary saturated fatty acid, can directly activate TLR has not
70 of them (>90%) were totally esterified with saturated fatty acids (capric, lauric, myristic, palmiti
71 ation by demonstrating that the much shorter saturated fatty acid, caprylate, has no significant effe
75 meat also contributes to the intake of fat, saturated fatty acids, cholesterol, and other substances
77 1.0 vs 41.4 +/- 0.3), together with a lower saturated fatty acid content (33.5 +/- 0.5 vs 47.3 +/- 0
79 whole adult animals, show an increase in the saturated fatty acid content of several phospholipid spe
81 nsidered challenging for health due to their saturated fatty acid content, yet they also provide bene
83 on of alkanes, alcohols, organic acids and n-saturated fatty acids coupled to sulfate reduction and t
84 ct MS analysis: C=C double bond formation on saturated fatty acids, covalent adducts formation via cl
86 hown that a diet with high levels of dietary saturated fatty acids decreases survival in septic mice,
87 s increased when cells are supplemented with saturated fatty acids, demonstrating the physiological r
88 tion and insulin resistance, suggesting that saturated fatty acids derived from the high-fat diet act
90 ferase long chain (Sptlc)-2, is required for saturated fatty acid-driven Nlrp3 inflammasome activatio
91 e numbers to produce new fat cells and store saturated fatty acids, enabling homeostasis of healthy f
92 Prolonged ingestion of a cholesterol- or saturated fatty acid-enriched diet induces chronic, ofte
93 preferential uptake into lipid storage while saturated fatty acid exhibits toxicity in hepatic cells.
95 Here we show that high fat diet (HFD) or saturated fatty acid exposure directly activates CCAAT/e
97 reinhardtii cells deprived of iron have more saturated fatty acid (FA), possibly due to the loss of f
99 ) macrophages showed an increased content of saturated fatty acids (FAs) and decreased omega-3 FAs (e
100 an HF diet rich in either monounsaturated or saturated fatty acids (FAs) and of exercise on EE and ch
104 catalyze the deacylation of the amide-linked saturated fatty acid from ceramide to generate sphingosi
105 or acute intracerebroventricular infusion of saturated fatty acid had less palmitoylated LMO4, less o
108 R influences the effect of substituting high-saturated fatty acid (HSFA) diets by isoenergetic altera
110 The DeltaplsX strain contained longer chain saturated fatty acids imparting a distinctly altered pho
113 lacement of TFA with STA compared with other saturated fatty acids in foods that require solid fats b
115 of lipin-2 in the proinflammatory action of saturated fatty acids in murine and human macrophages.
116 hat SCD1 inhibition promoted accumulation of saturated fatty acids in plasma and tissues and reduced
117 ty acids (MUFAs) or a high ratio of MUFAs to saturated fatty acids in plasma, reflecting a high activ
118 Dietary approaches to restore levels of saturated fatty acids in the intestine might reduce etha
120 cause of this specificity, the occurrence of saturated fatty acids in the TAG sn-2 position is infreq
125 SIS) in a PKA-dependent manner and prevented saturated fatty acid-induced apoptosis in human and rat
126 an upstream signaling component required for saturated fatty acid-induced ceramide biosynthesis.
127 diets with similar calcium contents affect a saturated fatty acid-induced increase in blood lipids di
128 iet, milk- and cheese-based diets attenuated saturated fatty acid-induced increases in total and LDL
130 indings identify pannexins as new targets of saturated fatty acid-induced inflammation in myotubes, a
131 ons between changes in percentage of dietary saturated fatty acid intake (%SFA) and changes in low-de
132 association between sleep duration and lower saturated fatty acid intake in younger (aged 20-64 y) ad
133 neonatal exposure to a maternal diet rich in saturated fatty acids is associated with altered activit
134 Here, we report for the first time that the saturated fatty acid lauric acid induced dimerization an
135 posure included the following: (i) decreased saturated fatty acids levels, (ii) retention of unsatura
137 olyunsaturated fatty acids predominated over saturated fatty acids, mainly due to the contribution of
139 fication of genes modulating the response to saturated fatty acids may reveal novel therapeutic strat
140 ts that high intake of total fat and certain saturated fatty acids may worsen prostate cancer surviva
141 other constituents in animal foods, such as saturated fatty acids, may confound the associations for
142 mentation with whey protein and medium-chain saturated fatty acids (MC-SFAs) improved postprandial li
143 was used for quantification of medium chain saturated fatty acids (MCSFAs) and the results revealed
145 SIMS) was used to measure the diffusivity of saturated fatty acid molecules from a fingerprint on a s
146 utrients were associated with increased risk-saturated fatty acid, monounsaturated fatty acid, and ol
147 ssociated significantly with increased risk: saturated fatty acid, monounsaturated fatty acid, and ol
148 T) catalyses the attachment of the 14-carbon saturated fatty acid, myristate, to the amino-terminal g
149 socaloric meals on 3 separate occasions (ie, saturated fatty acid, n-6 polyunsaturated fatty acid, an
154 thioester-linked modification of a 16-carbon saturated fatty acid onto the cysteine residue of a prot
156 t cancer risk (621 cases): caprate (10:0), a saturated fatty acid (OR: 1.77; 95% CI = 1.28, 2.43); ga
158 the rumenic acid (P < 0.01), and reduced the saturated fatty acids (P < 0.01) and the n-6/n-3 PUFA ra
159 demonstrated an increase in TFAs (p<0.001), saturated fatty acids (p<0.001) and decrease in cis-unsa
160 acrophages with lipopolysaccharide (LPS) and saturated fatty acid palmitate caused increased caspase-
161 n primary macrophages exposed to the dietary saturated fatty acid palmitate in combination with LPS.
163 expression is induced in macrophages by the saturated fatty acid palmitate, acts via its receptor Un
168 human ACSL1 potentiates lipotoxicity by the saturated fatty acid palmitate: silencing ACSL1 protects
169 of concept to show that, upon exposure to a saturated fatty acid, palmitate, macrophages release nuc
170 docosahexaenoic acid (DHA), relative to the saturated fatty acid palmitic acid (PA), on the hepatic
172 inoleic, oleic and elaidic acids) as well as saturated fatty acids (palmitic and stearic acids) in al
173 Caco-2/TC7 enterocytes were treated with the saturated fatty acid, palmitic acid, the insulin-signali
174 cGlcDAG provided that PE or PC contained one saturated fatty acid) paralleled the results observed pr
176 ence of the two factors: ripeness influenced saturated fatty acids, pigment content and deacetoxy ole
177 of the Healthy Diet Indicator (HDI) included saturated fatty acids, polyunsaturated fatty acids, mono
178 acids, alpha-linolenic acid, linoleic acid, saturated fatty acids, polyunsaturated fatty acids, omeg
181 ercial yarrow have higher content of fat and saturated fatty acids, proteins, ash, energy value, suga
184 antly lower mortality risk was observed when saturated fatty acids, refined carbohydrates, or trans f
188 r knowledge, no studies have evaluated a low-saturated fatty acid (SFA) (<7% calories) diet that cont
190 showed that palmitic acid-the most abundant saturated fatty acid (SFA) and the major SFA in the HFD
191 comparison between extreme quintiles, higher saturated fatty acid (SFA) and trans-fat intakes were as
192 CVD) risk together with the potential of its saturated fatty acid (SFA) content to raise low-density
195 UFA), polyunsaturated fatty acid (PUFA), and saturated fatty acid (SFA) in the breast adipose tissue.
196 ncubation of vascular endothelial cells with saturated fatty acid (SFA) increased the accumulation of
200 disease (CVD) risk involve reducing dietary saturated fatty acid (SFA) intake to </=10% of total ene
201 d dysfunction have been shown to depend upon saturated fatty acid (SFA) oversupply and de novo sphing
202 ion and polyunsaturated fatty acid (PUFA) to saturated fatty acid (SFA) ratio were higher and C18:2n-
203 otal cholesterol (TC), amplified response to saturated fatty acid (SFA) reduction, and increased card
204 ed that metabolism of palmitate, a prevalent saturated fatty acid (SFA), could drive solid-like domai
205 of various types of fatty acids, especially saturated fatty acid (SFA), on cardiovascular disease (C
206 ilk sold in the summer contained lower total saturated fatty acid (SFA; 67 vs 72 g/100g fatty acids)
207 e mechanism by which high fat diet (HFD) and saturated fatty acids (SFA) modulate fundamental circadi
208 polyunsaturated (PUFA) fatty acids and lower saturated fatty acids (SFA) than those from pigs raised
209 e role of lipid-modifying enzymes converting saturated fatty acids (SFA) to monounsaturated fatty aci
212 d in cell culture by exposing macrophages to saturated fatty acids (SFA), and endoplasmic reticulum (
213 ignificantly increased the concentrations of saturated fatty acids (SFA), mono-unsaturated fatty acid
214 calibrations were developed and proposed for Saturated Fatty Acids (SFA), Monounsatured Fatty Acids (
215 eate (18:1n9) and palmitoleate (16:1n7) from saturated fatty acids (SFA), stearate (18:0) and palmita
218 ng the association between intake of dietary saturated fatty acids (SFAs) and cardiovascular disease
219 affects insulin homeostasis via synthesis of saturated fatty acids (SFAs) and monounsaturated fatty a
220 carcinogenesis, and blood levels of specific saturated fatty acids (SFAs) and monounsaturated fatty a
221 ither monounsaturated fatty acids (MUFAs) or saturated fatty acids (SFAs) and their impact on glucose
231 ata support the benefits of reducing dietary saturated fatty acids (SFAs) on insulin resistance (IR)
232 tion and body composition during overfeeding saturated fatty acids (SFAs) or polyunsaturated fatty ac
234 cute elevation of NEFAs enriched with either saturated fatty acids (SFAs) or SFAs with long-chain (LC
237 racterized by elevated levels of circulating saturated fatty acids (SFAs) that associate with the pro
239 iscuss macronutrient replacement options for saturated fatty acids (SFAs) to optimize cardiovascular
240 s generally recommend reducing the intake of saturated fatty acids (SFAs) to reduce coronary artery d
241 fat-7, a fatty acid desaturase that converts saturated fatty acids (SFAs) to unsaturated fatty acids
242 rcise, but the effects of the replacement of saturated fatty acids (SFAs) with monounsaturated fatty
245 l diet with no pistachios [25% total fat; 8% saturated fatty acids (SFAs), 9% monounsaturated fatty a
246 rse genetics, revealed that NoDGAT2A prefers saturated fatty acids (SFAs), NoDGAT2D prefers monounsat
247 haracteristic of the Western diet, including saturated fatty acids (SFAs), omega-3 (n-3) fatty acids,
248 three high-fat (HF, 60% kcal) diets rich in saturated fatty acids (SFAs), omega-6 or omega-3 polyuns
249 ed total carbohydrate (grams per day), total saturated fatty acids (SFAs), percentage of energy from
250 vegetables, fish, dietary fibres, red meat, saturated fatty acids (SFAs), sodium, sugar-sweetened be
253 plant proteins, and ratio of unsaturated to saturated fatty acids, showed significant inverse associ
254 ecular weight and carbon preference index of saturated fatty acids significantly decreased within fin
256 tty acids, oleate and palmitoleate, from the saturated fatty acids stearate and palmitate, respective
257 At the molecular level, these events involve saturated fatty acid stimulation of the adenine nucleoti
259 ctic factors after exposure of adipocytes to saturated fatty acids, such as palmitate, occurs via tra
260 were not observed in mice fed a diet rich in saturated fatty acids, suggesting that the type of fat r
261 ttenuated SREBP activity maintain long-chain saturated fatty acid synthesis, while losing fatty acid
262 that hfRPE cells can metabolize palmitate, a saturated fatty acid that constitutes .15% of all lipids
263 levels of dietary cholesterol with specific saturated fatty acids that are abundant in WD exacerbate
264 n-2 in proinflammatory signaling mediated by saturated fatty acids that occurs concomitant with an en
265 profiles (except for minor organic acids and saturated fatty acids) throughout the assayed time inter
266 trachomatis that selectively scavenges host saturated fatty acids to be used for the de novo synthes
267 demonstrated as a shift from primarily C16:0 saturated fatty acids to C16:1 monounsaturated fatty aci
269 We determined whether lowering the ratio of saturated fatty acids to monounsaturated fatty acids in
270 the Calvin cycle to the de novo synthesis of saturated fatty acids to replace polyunsaturated ones in
271 , the transfer of myristic acid (a 14-carbon saturated fatty acid) to an N-terminal glycine catalyzed
272 predict polyunsaturated, monounsaturated and saturated fatty acids, together with triacylglycerides,
274 een implicated, the exact mechanisms whereby saturated fatty acids trigger beta-cell death remain elu
275 R4 agonists and omega-3 fatty acids, but not saturated fatty acids, trigger mitosis and adipogenesis
279 is required for the synthesis of C28 and C30 saturated fatty acids (VLC-FA) and of C28-C38 very long
284 Fatty acid composition - at the exception of saturated fatty acids - was affected by dietary manageme
287 erols and sphingolipids with very long chain saturated fatty acids when compared with the bulk of the
289 packed with cholesterol, sphingomyelin, and saturated fatty acids, whereas disordered domains contai
290 Deletion of SCT1 decreases the content of saturated fatty acids, whereas overexpression of SCT1 dr
291 nd other phospholipids were also enriched in saturated fatty acids, which could reflect limited acyl
292 ts as the result of increased levels of free saturated fatty acids, which promote insulin receptor ub
293 lammation and elevated levels of circulating saturated fatty acids, which trigger inflammatory respon
294 milk that contains excessive long chain and saturated fatty acids, which triggers ceramide accumulat
295 uivalents as FADH2 through beta-oxidation of saturated fatty acids, while COD:N of 11:1 do it through
296 ent and T2D (P-trend = 0.24), but intakes of saturated fatty acids with 4-10 carbons, lauric acid (12
298 een TLR4-mediated inflammatory signaling and saturated fatty acids with regard to ceramide generation
299 saturated fatty acids), or milk fat (rich in saturated fatty acids) with or without fish oil (rich in
300 is of retinal NSLs indicated an abundance of saturated fatty acids, with the presence of VLC-FAs but