ライフサイエンスコーパス: scaffold protein

1 derstanding the biological functions of this scaffold protein.

2 odel to understand signal amplification by a scaffold protein.

3 triphosphatase-activating protein 1 (IQGAP1) scaffold protein.

4 rane beta-barrel Escherichia coli OmpLA as a scaffold protein.

5 transmembrane beta-barrel E. coli PagP as a scaffold protein.

6 (SNX9), a central multifunctional endocytic scaffold protein.

7 belt" mechanism for signal amplification by scaffold proteins.

8 ubiquitously expressed lipid raft-associated scaffolding protein.

9 interaction with Ajuba, an actin binding and scaffolding protein.

10 cognate transport machinery and specific AZ-scaffolding proteins.

11 n of G protein-coupled receptor signaling by scaffolding proteins.

12 eneous aberrant structures in the absence of scaffolding proteins.

13 and MDA5 by binding to and sequestering the scaffold proteins 14-3-3e and 14-3-3eta.

14 in the down-regulation of Discs Large MAGUK Scaffold Protein 3 (DLG3), resulting in Golgi complex fr

15 ring development where it interacts with the scaffolding protein 4.1B and the dynein regulator lissen

16 repeat protein (CSA), CSB, or UV-stimulated scaffold protein A (UVSSA) homologs, whose orthologs are

17 espectively, of the AMPA-receptor regulatory scaffold protein A-kinase anchoring protein (AKAP) 79/15

18 The intrinsically disordered scaffold proteins AFF1/4 and the transcription elongatio

19 total mGlu1 protein or its coupling to Homer scaffolding proteins after methamphetamine withdrawal, n

20 The scaffolding protein AKAP350A is known to localize to the

21 nstructed truncated versions of the membrane scaffold protein, allowing the preparation of a range of

22 Scaffolding protein also catalyzes oligomerization of mo

23 ure virions, suggesting that it might be the scaffold protein, an essential head morphogenesis protei

24 +) exchange regulatory cofactor (NHERF)-1, a scaffolding protein, anchors multiple membrane proteins

25 SLX4, also known as FANCP, acts as a scaffold protein and coordinates multiple endonucleases

26 ctor receptor-associated factor 2 (TRAF2), a scaffold protein and E3 ubiquitin ligase important for i

27 ts of EARLY FLOWERING 3 (ELF3)(4,7), a large scaffold protein and key component of temperature sensin

28 summarize current knowledge about the Atg11 scaffold protein and review recent findings in the conte

29 It currently contains 273 scaffold proteins and 1118 associated signaling pathways

30 tionally predicted, experimentally validated scaffold proteins and associated signaling pathways.

31 at GPCRs interact with 14-3-3 signal adaptor/scaffold proteins and that this interaction regulates re

32 pacity, MALT1 has two functions, acting as a scaffolding protein and as a substrate-specific protease

33 mponent, has been broadly characterized as a scaffolding protein and is required for the recruitment

34 n domains in the kinase or via anchoring and scaffolding proteins and can drastically increase the ki

35 ely form via interactions among postsynaptic scaffolding proteins and receptors and align with putati

36 ion, we observed marked loss of postsynaptic scaffolding proteins and reduced complexity of the sub-s

37 as associated with reduced recruitment of TZ scaffolding proteins and reduced Smoothened levels at ci

38 otubules, dynein, the JIP3 microtubule motor scaffold protein, and Arf6, a JIP3 interacting protein,

39 nding of CCCTC-binding factor, a chromosomal scaffolding protein, and increases histone and DNA methy

40 depend on interactions between claudins, ZO scaffolding proteins, and the cytoskeleton.

41 Here, we investigate how the actomyosin scaffold protein anillin contributes to epithelial mecha

42 l Cell, Budnar and colleagues report how the scaffolding protein anillin uses cycles of transient bin

43 tor Ecm29 and the axon initial segment (AIS) scaffold protein ankyrin G.

44 ap that variation to a polymorphic dendritic scaffold protein, ARCP-1, expressed in sensory neurons.

45 Scaffold proteins are central players in regulating the

46 PDZ domain scaffold proteins are molecular modules orchestrating ce

47 PSD-95 MAGUK family scaffold proteins are multi-domain organisers of synapti

48 enin and reductions in synaptic adhesion and scaffold proteins as major consequences of beta-catenin

49 Scaffold proteins assemble these networks by recruiting

50 Our findings are consistent with a scaffold protein assignment for SPN3US gp22, although di

51 osphorylation in a complex that includes the scaffold protein Axin and associated kinases.

52 bstitutions ranged from inefficient internal scaffolding protein B binding to faulty procapsid elonga

53 re, we show that Rsr1-GDP interacts with the scaffold protein Bem1 in early G1, likely hindering the

54 The intracellular scaffold protein beta-arrestin-2 is implicated in tolera

55 dulated by heterotrimeric G proteins and the scaffold proteins beta-arrestin 1 and 2.

56 The IQGAP family of scaffold proteins binds to and regulates multiple signal

57 despite harboring prominent binding sites to scaffold proteins, Ca(V)2.1(+47) persistently displayed

58 /zonula occludens-1-and WW domain-containing scaffold protein called membrane-associated guanylate ki

59 ariety of putative intermediate Fe/S cluster scaffold proteins can cause disease states, including mu

60 This suggests a mechanism for how scaffolding proteins can allosterically modify the outpu

61 Scaffolding proteins can preferentially couple specific

62 identified TRIM28 (tripartite protein 28), a scaffold protein capable of recruiting a number of chrom

63 protein kinase C-theta (PKCtheta) through a scaffold protein, CARD10.

64 of neuron-targeted overexpression of an MLR scaffold protein, caveolin-1 (Cav-1) (via a synapsin pro

65 Mutations in the caveolae scaffolding protein, caveolin-3 (Cav3), have been linked

66 1 to double-strand breaks (DSBs) through the scaffold protein CCDC98 (Abraxas) and facilitates DNA da

67 Interactions of NEMO, a scaffolding protein central to NF-kappaB signaling, exem

68 d roles in autophagy and trafficking, Ambra1 scaffolds protein complexes at chromatin, regulating tra

69 lustrate the self-regulatory properties that scaffold proteins confer on signalling pathways.

70 targeting CaN to substrates, inhibitors, and scaffold proteins containing docking motifs with the con

71 the receptor or recruitment of beta-arrestin scaffolding proteins could preserve the analgesic proper

72 Because it does not interact with the scaffold protein cullin 1 (CUL1), we hypothesized that F

73 74 morphogenesis, 240 copies of the external scaffolding protein D organize 12 pentameric assembly in

74 id elongation reactions mediated by external scaffolding protein D.

75 ransmembrane protein A17 and the capsid-like scaffold protein D13 was sufficient to form similar ER-a

76 multiple ankyrin repeat domains 3 (SHANK3B) scaffolding protein, defective expression of which has b

77 -CDF) of CaV1.3 channels that depends on the scaffolding protein densin and CaMKII and that outlasts

78 Assess occurrence of the dendritic spine scaffolding protein Drebrin as a pathophysiologically re

79 iso4e) and two isoforms of the large subunit scaffolding protein eIFiso4G (i4g1 and i4g2).

80 The scaffold protein ERC1/ELKS and its partners promote cell

81 Mice deficient for either of these scaffold proteins exhibit distinct maturation patterns o

82 d residues within the RING-H2 domains of the scaffold proteins Far1 and Ste5, which are also phosphor

83 We previously showed that seipin acts as a scaffold protein for AGPAT2, whose disruption also cause

84 When Raptor, a critical scaffold protein for mammalian target of rapamycin compl

85 larly, Crabp1 acts as a novel atRA-inducible scaffold protein for Raf/Mek/Erk in cells without growth

86 timerization of G3BP1, which is an essential scaffold protein for SG assembly.

87 Moreover, LAT, an essential scaffold protein for TCR signaling, is not required for

88 builds diverse binding sites into different scaffold proteins for a variety of target molecules.

89 egradation and, in yeast, recruit Atg11, the scaffolding protein for selective autophagy initiation.

90 In the central nervous system (CNS), Homer scaffolding proteins form signaling complexes with two C

91 Disabled-2 (Dab2) is a multifunctional scaffold protein frequently downregulated in cancer that

92 n in understanding the general principles of scaffold protein functions.

93 ly, we show that L(pro) cleaves the known SG scaffold proteins G3BP1 and G3BP2 but not TIA-1.

94 a suggest that aphthoviruses actively target scaffolding proteins G3BP1 and G3BP2 and antagonize SG f

95 y, we observed that L(pro) can cleave the SG scaffolding proteins G3BP1 and G3BP2.

96 Defects in the mRNA export scaffold protein GANP, encoded by the MCM3AP gene, cause

97 hibitory GABAergic postsynapses requires the scaffold protein gephyrin and the guanine nucleotide exc

98 esolution the distribution of the inhibitory scaffold protein gephyrin in response to protocols induc

99 naling by direct binding to the postsynaptic scaffolding protein gephyrin.

100 ynamic regulation of GABA(A)R binding to the scaffolding proteins gephyrin and collybistin.

101 P2/T507K possesses a higher affinity for the scaffolding protein Grb2-associated binding protein 1 (G

102 SHOC2 scaffold protein has been mainly related to oncogenic ER

103 a lipid bilayer surrounded by a boundary of scaffold proteins have emerged as a powerful tool for me

104 Genetic ablation of the FA-associated scaffold protein Hic-5 in mouse cancer-associated fibrob

105 of vimentin organization/dynamics by the FA scaffold protein Hic-5 via modulation of RhoGTPases and

106 The scaffold protein HIGH CHLOROPHYLL FLUORESCENCE244 (HCF24

107 Keratin 16 (K16) is a cytoskeletal scaffolding protein highly expressed at pressure-bearing

108 The scaffolding protein Homer assembles SOC complexes, but i

109 l-drinking elevates BNST levels of the mGlu5-scaffolding protein Homer2 and activated extracellular s

110 de novo synthesis of a [2Fe-2S] cluster on a scaffold protein; Hsp70 chaperone-mediated trafficking o

111 We propose that motifs of the scaffold protein IKKgamma/NEMO partly facilitate such fu

112 eodomain finger-containing (BRPF) family are scaffolding proteins important for the recruitment of hi

113 The SHANK3 gene encodes a postsynaptic scaffold protein in excitatory synapses, and its disrupt

114 and recruitment domain 11 (CARD11) encodes a scaffold protein in lymphocytes that links antigen recep

115 To understand the functions of scaffold proteins in cell signaling, we developed a, to

116 However, the role of scaffold proteins in these processes is poorly understoo

117 rtant new insights into the role of FAK as a scaffolding protein in molecular complexes that regulate

118 omplementation group A (XPA) is an essential scaffolding protein in the multiprotein nucleotide excis

119 RLTPR encodes a recently described scaffolding protein in the T-cell receptor signaling pat

120 Here we show that eIF4G, the major scaffolding protein in the translation initiation comple

121 iated guanylate kinase (Dlg/MAGUK) family of scaffolding proteins in beta-catenin signaling, we studi

122 multiple pre- and post-synaptic membrane or scaffolding proteins including glutamatergic ion channel

123 The other has been the use of artificial scaffold proteins, including Affimers.

124 tracellular compartments by association with scaffold proteins, including by multivalent A-kinase anc

125 to DNA damage is organised by multi-domain 'scaffold' proteins, including 53BP1 and TOPBP1, which re

126 repeat proteins, as well as their associated scaffolding proteins, including SHANKs and others, on so

127 e growth factor I (IGF-I) signal through the scaffold protein insulin receptor substrate 1 (IRS-1).

128 the CAV3 gene encoding caveolin-3 (Cav3), a scaffolding protein integral to caveolae in cardiomyocyt

129 IQGAP1 is a scaffold protein involved in a range of cellular activit

130 Anillin is a conserved scaffold protein involved in organizing the structural c

131 dates, MPP7 (MAGUK p55 subfamily member 7, a scaffolding protein involved in cell-cell contacts) and

132 previously shown that Huntingtin (HTT), the scaffolding protein involved in Huntington's disease, re

133 protein (CD2AP), a slit diaphragm-associated scaffolding protein involved in survival and regulation

134 or metastasis and cell migration through the scaffold protein IQ motif-containing GTPase-activating p

135 ac1 and nuclear ERK activity depended on the scaffolding proteins IQ motif-containing GTPase-activati

136 is mediated by ceramide signaling on an ERK scaffold protein, IQ motif containing GTPase activating

137 We found that OX40 associated with a scaffold protein, IQ motif-containing GTPase-activating

138 The scaffold protein IQGAP1 regulates intracellular signalin

139 The scaffold protein IQGAP1 was recently identified in a scr

140 This interaction is regulated by the scaffolding protein IRBIT, which is released by stimulat

141 hirlin), a PDZ domain-containing submembrane scaffold protein, is present at the tips of the tall ste

142 uitously expressed cytoplasmic lipid droplet scaffolding protein, is hypothesized to contribute to NA

143 se NFS1 that is activated by frataxin (FXN), scaffold protein ISCU, accessory protein ISD11, and acyl

144 sulfurase enzyme IscS provides sulfur to the scaffold protein IscU, which templates the Fe-S cluster

145 to generate a persulfide species on the Fe-S scaffold protein ISCU2.

146 st, [2Fe-2S] clusters are synthesized on the scaffold protein ISCU2; second, these clusters are trans

147 (ACP), and the iron-sulfur cluster assembly scaffold protein (ISCU2).

148 ghlights that supramolecular assembly of the scaffold protein, its enzymatic processing, and its abil

149 cond WW domain (WW2) of the kidney and brain scaffolding protein, KIBRA, has an isoleucine (Ile-81) r

150 Tks4 is a scaffold protein known to organize the cytoskeleton of l

151 ctly interacts with each of the Fe-S cluster scaffold proteins known to ligate [2Fe-2S] clusters, ISC

152 containing CaMKII and Shank3, a postsynaptic scaffolding protein known to interact with L-type calciu

153 The C. elegans scaffold protein KRI-1, ortholog of mammalian KRIT1/CCM1

154 daptor protein 14-3-3 that links Rap1 to the scaffold protein KSR.

155 yndrome (HGPS), a mutant form of the nuclear scaffold protein lamin A distorts nuclei and sequesters

156 A, the farnesylated precursor of the nuclear scaffold protein lamin A.

157 cal reconstitution shows that Bre1 binds the scaffold protein Lge1, which possesses an intrinsically

158 While the scaffolding protein LGN is known to determine initial sp

159 a hippocampal CA3 specifically expressed PDZ scaffold protein Lnx1 required for initial social behavi

160 also called AKAP450/CG-NAP/AKAP9) is a large scaffolding protein located at both the centrosome and G

161 mpartment organized by the large multivalent scaffold protein mAKAPalpha promotes neuronal survival a

162 erinuclear cAMP compartment organized by the scaffold protein mAKAPalpha that is necessary and suffic

163 phatase 2A) at signalosomes organized by the scaffold protein mAKAPbeta (muscle A-kinase anchoring pr

164 posite binding sites are built into existing scaffold proteins matching the intended binding site geo

165 ts into SHOC2 function and reveals that this scaffold protein may be essential to activate a novel me

166 ents still occur, such as recruitment of the scaffold protein MDC1 to phosphorylated histone H2AX at

167 ptic active zones, arrays of large conserved scaffold proteins mediate fast and temporally precise re

168 sis of human metastatic genes identified the scaffolding protein metastasis suppressor 1 (MTSS1) as a

169 emical approaches, we identified the initial scaffold protein, mitochondrial ISCU (ISCU2) and the sec

170 a novel binding partner of the mTOR complex scaffold protein, mLST8.

171 eins Mms13 and MmsF on stem-loop coiled-coil scaffold proteins (Mms13cc/MmsFcc).

172 Scaffold proteins modulate signalling pathway activity s

173 The nanodiscs were formed with major scaffold protein (MSP) and different phospholipids, wher

174 a, we engineered a series of mutant membrane scaffold proteins (MSP) that do not affect nanodisc form

175 ration, and the nuclear concentration of the scaffold protein multi-sex combs (Mxc), which is control

176 Both MEF2D and CaN bind the scaffold protein muscle A-kinase-anchoring protein beta

177 Mutations in NBEAL2, the gene encoding the scaffolding protein Nbeal2, are causal of gray platelet

178 racts with the HECT domain protein HERC2 and scaffold protein NEURL4, and knockdown of HERC2 or NEURL

179 Multidomain scaffolding proteins nucleate assembly and direct locali

180 The abnormal particles retained the D13 scaffold protein of immature virions, were severely defi

181 TAV interacts specifically with a scaffold protein of the decapping complex VARICOSE (VCS)

182 ich phosphorylates MOB1A, a highly conserved scaffold protein of the Hippo pathway.

183 AF4/FMR2 family member 4 (AFF4) is the scaffold protein of the multisubunit super-elongation co

184 Disrupted in Schizophrenia 1 (DISC1) is a scaffolding protein of significant importance for neurod

185 ins belonging to a protein called Whirlin, a scaffolding protein of the hearing apparatus.

186 Reduced protein level of a requisite scaffolding protein of the initiation complex, eIF4G1, d

187 Reduced protein level of a requisite scaffolding protein of the initiation complex, eIF4G1, d

188 Scaffold proteins organize cellular processes by bringin

189 nase alpha (PI3K-C2alpha) acting as limiting scaffold protein organizing clathrin and TACC3 complex c

190 The Cas family scaffolding protein p130Cas is a Src substrate localized

191 of SRC family kinase (SFK) signaling by the scaffold protein, PAG1, influences cell fate decisions f

192 ed microRNA-mediated repression of the Golgi scaffolding protein PAQR11.

193 The scaffold protein PAR3 and the kinase PAR1 are essential

194 we show that Hic-5, a close relative of the scaffold protein paxillin, is essential for the formatio

195 s) and the expression and organization of LD scaffold proteins perilipin-2 (PLIN2) and perilipin-5 (P

196 or the strong binding between the PDZ domain scaffold proteins, PICK1 and PSD-95, and their cognate t

197 ating cell nuclear antigen (PCNA), a nuclear scaffolding protein pivotal in DNA synthesis, controls n

198 st that the conformational fluctuations in a scaffold protein play a positive role in recruiting down

199 Scaffold proteins play a critical role in an increasing

200 he SHANK3 gene, which encodes a postsynaptic scaffold protein, play a causative role in autism spectr

201 n into dodecameric rings, possibly forming a scaffolding protein-portal protein nucleation complex th

202 ber by promoting degradation of the synaptic scaffold protein, postsynaptic density protein 95 (PSD-9

203 SD) protein that binds to PDZ domains of the scaffold protein PSD-95.

204 = 0.68) when overexpressing the postsynaptic scaffolding protein PSD-95, which increased receptor clu

205 where it associates with and stabilizes the scaffolding protein PSD95, promoting dendritic spine mat

206 ession from clinical samples, and found that scaffolding protein RACK1 deficiency plays a significant

207 We have previously shown that the scaffolding protein Ran-binding protein 9 (RanBP9), whic

208 than tightly clustered by the intracellular scaffolding protein, rapsyn, as at the intact neuromuscu

209 Furthermore, we show that the scaffold protein raptor, that typically recruits mTOR su

210 CARD11 is a multidomain signaling scaffold protein required for antigen receptor signaling

211 Axin is a key scaffolding protein responsible for the formation of the

212 n (PRU) domain to C-terminal residues of the scaffolding protein RPN2.

213 We previously showed that the scaffolding protein SAV1 promotes Hippo signaling by cou

214 Mutations in the synaptic scaffolding protein SHANK3 are a major cause of autism a

215 IFICANCE STATEMENT Mutations in the synaptic scaffolding protein SHANK3 are commonly associated with

216 The scaffold protein Shoc2 amplifies the activity of the ERK

217 te motif-containing proteins are a family of scaffold proteins shown to regulate gene silencing, cell

218 IGF-I receptor signals through an alternate scaffold protein, SHPS-1, resulting in pathophysiologic

219 s the interaction between membrane proteins, scaffolding proteins, signalling proteins and enzymes to

220 ises the NAD-dependent deacetylase Sir2, the scaffolding protein Sir4, and the nucleosome-binding pro

221 The chromatin scaffolding protein SMCHD1 (structural maintenance of ch

222 We examined whether the scaffolding protein sodium-hydrogen exchanger regulatory

223 and show that CpmB competes with the 80alpha scaffolding protein (SP) for a binding site on the capsi

224 Scaffolding proteins (SP) drive assembly by chaperoning

225 Scaffolding proteins (SPs) are required for the capsid s

226 , the portal forms a nucleation complex with scaffolding proteins (SPs) to initiate procapsid (PC) as

227 ion complex composed minimally of portal and scaffolding proteins (SPs).

228 the mitogen-activated protein kinase (MAPK) scaffold protein Ste5.

229 The signaling scaffold protein STRAP is upregulated in several cancers

230 itic instability and alterations in synaptic scaffolding proteins, studies of glutamate receptor leve

231 Mitogen-activated protein kinase (MAPK) scaffold proteins, such as IQ motif containing GTPase ac

232 ignal through Gi/o-coupled G-proteins and/or scaffolding proteins, such as beta-arrestin, we find tha

233 An additional interaction detected with the scaffold protein SUFD enabled us to build a model in whi

234 Here we find that the core active-zone scaffold proteins SYD-2 (also known as liprin-alpha) and

235 redistributed during the evolution of a two-scaffolding-protein system.

236 The post-synaptic scaffolding protein tamalin has been shown to interact w

237 The PARP enzyme and scaffolding protein tankyrase (TNKS, TNKS2) uses its ank

238 opeptidase IRAP and its binding partner, the scaffolding protein tankyrase.

239 However, most scaffold proteins tend to simultaneously bind more than

240 Scaffold proteins tether and orient components of a sign

241 association domain family 1A (RASSF1A) is a scaffold protein that acts as a tumour suppressor.

242 XRCC1 is a molecular scaffold protein that assembles multi-protein complexes

243 omerase IIbeta-binding protein 1 (TopBP1), a scaffold protein that binds ATR and recruits it to sites

244 tor interacting protein 1 (GRIP1), a crucial scaffold protein that delivers AMPARs to synapses, durin

245 functional interaction of RBPJ with SHARP, a scaffold protein that forms a transcriptional repressor

246 a pleckstrin homology (PH) domain-containing scaffold protein that increases the efficiency of Ras si

247 TONSL is a multi-domain scaffold protein that interacts with DNA replication and

248 ng GTPase-activating protein 1 (IQGAP1) is a scaffold protein that interacts with numerous binding pa

249 One target of this feedback is Ste5, a scaffold protein that promotes Fus3 activation.

250 ynaptic accumulation of gephyrin, which is a scaffold protein that recruits GABAA receptors (GABAA Rs

251 Integrin-linked kinase (ILK) is a scaffold protein that regulates microtubule stability an

252 IQGAP1 is a key scaffold protein that regulates numerous cellular proces

253 SQT is a stefin A derived scaffold protein that was used as a model to study possi

254 chizophrenia 1 (DISC1) is a multi-functional scaffolding protein that has been associated with neurop

255 S-SCAM is a unique synaptic scaffolding protein that localizes to both excitatory an

256 cells by knocking down ANLN, a cytoskeletal scaffolding protein that regulates cytokinesis and might

257 PSD-95 is a scaffolding protein that regulates the synaptic localiza

258 d guanylate kinases (MAGUKs) are a family of scaffolding proteins that are expressed in excitatory gl

259 ) exchanger regulatory factor (NHERF) family scaffolding proteins that are required for many aspects

260 T The presynaptic active zone is composed of scaffolding proteins that functionally interact to local

261 hatases and kinases complex, are multidomain scaffolding proteins that play important biologic roles.

262 s mammalian homologues, LLGL1 and LLGL2, are scaffolding proteins that regulate the establishment of

263 t occurs through initial mobilization of the scaffolding protein Tks5 and F-actin accumulation, follo

264 t RA T cells abundantly express the podosome scaffolding protein TKS5, which enables them to form tis

265 The related scaffold proteins, TKS5 and TKS4, are key components of

266 By considering FAM83H a scaffold protein to anchor CK1s, further molecular chara

267 Mechanistically, ZFP161 acts as a scaffolding protein to facilitate the interaction betwee

268 Caveolin-1 acts as a scaffolding protein to functionally regulate signaling m

269 ur indirectly or possibly require additional scaffolding proteins to facilitate regulation.

270 3 "writer," and with TRIM28, an abundant HP1 scaffolding protein, to form complexes with increased mu

271 After de novo formation on scaffold proteins, transfer proteins load Fe-S clusters

272 granules, Piwi protein Aubergine binds to a scaffold protein Tudor, which contains 11 Tudor domains.

273 1 bound, phosphorylated, and inactivated KSR scaffolding proteins ultimately inhibited Ras/ERK signal

274 al cellulosome assembly, including conserved scaffolding proteins unique to the Neocallimastigomycota

275 aptic density (PSD) contains a collection of scaffold proteins used for assembling synaptic signaling

276 des its opposing lipid kinase, Fab1, and the scaffold protein Vac14.

277 PIKfyve complex comprises five copies of the scaffolding protein Vac14 and one copy each of the lipid

278 co-expressed with mRNA encoding the membrane scaffold protein variant MSP1D1.

279 argeting the decapping machinery through the scaffold protein VARICOSE, indicating that 5'-3' mRNA de

280 In one-scaffolding-protein virus assembly systems, coat protein

281 nhibitor, pointed to a mechanism involving a scaffolding protein, Wag31, involved in polar elongation

282 parate study, we reported that the autophagy scaffolding protein WDFY3 is required for cerebral corti

283 Based on the saposin-A (SapA) scaffold protein, we demonstrate the suitability of a si

284 One molecule in the network is a scaffold protein, whereas the other two are its binding

285 mes are spatially controlled by cytoskeletal scaffolding proteins, which both recruit and organize th

286 f ankyrins, spectrins and other cytoskeletal scaffolding proteins, which cluster ion channels.

287 xes and contain cytoskeletal, regulatory and scaffolding proteins, which regulate channel conductance

288 lation method to the model, we show that the scaffold proteins will promote not only thermodynamics b

289 ucocorticoid receptor and beta-arrestin-1, a scaffold protein with a well-established role in G prote

290 Scribble (Scrib) is a scaffold protein with multifunctional roles in PCP, tigh

291 bule actin cross linking factor 1 (MACF1), a scaffolding protein with binding sites for microtubules

292 se disorders are those encoding postsynaptic scaffolding proteins with roles in synaptic transmission

293 Elp1 is best known as a scaffolding protein within the nuclear hetero-hexameric

294 ganization of neurotransmitter receptors and scaffolding proteins within the postsynaptic density.

295 protein (also known as KAP1 and TIF1beta), a scaffolding protein without intrinsic repressive or DNA-

296 versely, the interaction of Polbeta with the scaffold protein X-ray repair cross complementing 1 (XRC

297 The scaffold protein X-ray repair cross-complementing 1 (XRC

298 break repair is the rapid recruitment of the scaffold protein XRCC1 that interacts with, stabilizes a

299 ng of DNA from the histone octamer; that the scaffolding protein XRCC1 enhances the ligation; that th

300 9 (AC9) is found tightly associated with the scaffolding protein Yotiao and the IKs ion channel in he