ライフサイエンスコーパス: scapularis

1 gnosis using the natural tick vector (Ixodes scapularis).

2 Pediculus humanus and a tick species Ixodes scapularis.

3 mice or the acquisition of spirochetes by I. scapularis.

4 role in B. burgdorferi persistence within I. scapularis.

5 uired for spirochetal colonization of Ixodes scapularis.

6 e carried in the "black-legged" tick, Ixodes scapularis.

7 cluding the Lyme disease vector tick, Ixodes scapularis.

8 ila) are both transmitted by the tick Ixodes scapularis.

9 YFV, 2 Haemagogus leucocelaenus, and 1 Aedes scapularis.

10 ll line isolated from the vector tick Ixodes scapularis.

11 ll line, IDE8, derived from embryonic Ixodes scapularis.

12 tsial symbiont isolated from the tick Ixodes scapularis.

13 nd southern Iowa) the geographic range of L. scapularis.

14 ponse in C3H/HeJ mice exposed to infected I. scapularis.

15 ived from a putative vector, the tick Ixodes scapularis.

16 e disease, is transmitted by the tick Ixodes scapularis.

17 d fitness in the clinically relevant tick I. scapularis.

18 vaccine and subsequently challenged with I. scapularis.

19 tions of the blacklegged tick vector, Ixodes scapularis.

20 t were tested using Aedes aegypti and Ixodes scapularis.

21 erminal kinase (JNK) signaling pathway in I. scapularis.

22 human exposure to the Lyme disease vector-I. scapularis.

23 resent in the saliva of the hard tick Ixodes scapularis.

24 easing the cold tolerance and survival of I. scapularis.

25 nown to infect the black-legged tick, Ixodes scapularis.

26 We show that the gut microbiota of I. scapularis, a major vector of the Lyme disease spirochet

27 Rabbits or guinea pigs infested with Ixodes scapularis acquire resistance to tick bites, a phenomeno

28 ether impaired TLR signaling enhances Ixodes scapularis acquisition of B. burgdorferi, we fed nymphs

29 Of note, although optimized for I. scapularis adult ticks, I. scapularis nymphs, other tick

30 re were designed to delineate the role of I. scapularis and B. burgdorferi in modulation of the host

31 tion machinery is present in the tick Ixodes scapularis and demonstrate that the E3 ubiquitin ligase

32 the prominent salivary gland proteins in I. scapularis and demonstrate the presence of a potent anti

33 ic reprogramming in the tick ectoparasite I. scapularis and determined that the rickettsial bacterium

34 hern strains, isolated from the ticks Ixodes scapularis and Ixodes affinis, the cotton rat (Sigmodon

35 Ixodes scapularis and Ixodes pacificus are the predominant vect

36 le that involves the arthropod vector Ixodes scapularis and mammalian reservoirs.

37 t N40-75 spirochetes can readily colonize I. scapularis and multiply during tick engorgement.

38 imals challenged with field-collected Ixodes scapularis and propagated in HL60 cells.

39 Five of the six novel isolates from I. scapularis and the isolate from I. dentatus were from ti

40 annual changes in population densities of I. scapularis and, presumably, a corresponding change in th

41 mnants of blood in blacklegged ticks (Ixodes scapularis) and correctly determine the vertebrate speci

42 ting local populations of deer ticks (Ixodes scapularis) and to test the fit to a neutral IAM.

43 he gut of the intermediate tick host (Ixodes scapularis), and that this interaction is mediated, at l

44 microenvironments of the tick vector, Ixodes scapularis, and a mammalian host.

45 sensu lato in A. americanum, I. affinis, I. scapularis, and small mammals to new sites in Florida.

46 rotein 20 (Salp20) is a member of the Ixodes scapularis anti-complement protein-like family of tick s

47 rototypic member of a family of potential I. scapularis anticoagulants, expressed and secreted in tic

48 ressed by Ixodes scapularis ticks, called I. scapularis antifreeze glycoprotein (IAFGP), that has hig

49 gocytophilum induces ticks to express Ixodes scapularis antifreeze glycoprotein (iafgp), which encode

50 We identified an I. scapularis antifreeze glycoprotein, designated IAFGP, an

51 ericanum, Dermacentor variabilis, and Ixodes scapularis are among the principal tick species associat

52 otein that was discovered recently in Ixodes scapularis as a tick protective antigen and has a role i

53 es) from the clinically relevant tick Ixodes scapularis at a single-cell resolution.

54 ere given cytokines for 10 days after Ixodes scapularis attachment.

55 antibodies when its arthropod vector, Ixodes scapularis, begins feeding on a mammalian host.

56 New York, in 1991-1994, a mean of 178,889 I. scapularis bites (20.4 per 100 person-years) and a mean

57 ti and Culex quinquefasciatus), tick (Ixodes scapularis), body louse (Pediculus humanus), kissing bug

58 of B. burgdorferi throughout the range of I. scapularis-borne Lyme disease using multilocus sequence

59 t the typical vector of Lyme disease, Ixodes scapularis, can acquire the spirochetes from infected ma

60 For example, the highly passaged Ixodes scapularis cell line ISE18 and Ixodes ricinus cell lines

61 dorferi in nymphal blacklegged ticks (Ixodes scapularis) collected at the sites the following year in

62 4 through December 1995 from the tick Ixodes scapularis, collected from vegetation, and from the rode

63 pression is generally elevated within Ixodes scapularis compared with mice.

64 erious phenotype of silenced ticks making I. scapularis cystatins attractive targets for development

65 ions in other animals, the content of the I. scapularis degradome is ~6.0% (14/233) aspartic, ~19% (4

66 Using an Ixodes scapularis-derived cell line, key Argonaute proteins inv

67 NCE We isolated POWVs from LI deer ticks (I. scapularis) directly in VeroE6 cells, and sequencing rev

68 rference-mediated repression of salp15 in I. scapularis drastically reduced the capacity of tick-born

69 Acquired resistance to I. scapularis due to repeated tick exposure has the potenti

70 e interactions between B. burgdorferi and I. scapularis during infection, as well as interactions wit

71 Extracellular vesicles from Ixodes scapularis enable tick feeding and promote infection of

72 Subjects bitten by I. scapularis evidenced an increase in anti-rTC antibody le

73 When Ixodes scapularis feed on an infected vertebrate host, spiroche

74 POWV-infected and uninfected I. scapularis females were fed on naive mice for 1, 3, and

75 by the presence of B. burgdorferi in Ixodes scapularis, first indicating that spirochaetes might use

76 One species, I. scapularis, from eastern North America has two forms of

77 nstrate that RNA interference can silence I. scapularis genes and disrupt their physiologic function

78 These 47 clones encoded 14 different I. scapularis genes, including a glutathione peroxidase hom

79 ionally, the recent sequencing of the Ixodes scapularis genome and characterization of tick immune de

80 we present the assembly of a 2.23-Gb Ixodes scapularis genome by sequencing two haplotypes within on

81 The I. scapularis genome does not apparently encode for putativ

82 of three encoding genes representing Ixodes scapularis genome paralogs, IrCD1 is the most distinct e

83 The Ixodes scapularis Genome Project (IGP), the first to sequence a

84 rypsin-like serine protease family in the I. scapularis genome where it is ~12.7% (28/233) of the deg

85 ll repertoire of proteases encoded by the I. scapularis genome) represent ~1.14% of the 20485 putativ

86 ne-stop index of proteases encoded by the I. scapularis genome.

87 protease enzymes that are encoded by the I. scapularis genome.

88 The I. scapularis glutathione peroxidase homologue, named salp2

89 e reduced B. burgdorferi adherence to the I. scapularis gut in vivo, thereby preventing efficient col

90 pB is expressed by spirochetes in the Ixodes scapularis gut.

91 he hard tick and Lyme disease vector, Ixodes scapularis, has a repertoire of compounds that counterac

92 ) treated with the saliva of the tick Ixodes scapularis have reduced expression of beta(2) integrins,

93 e role that nymphal and female ticks, Ixodes scapularis, have in the epidemiology of Lyme disease is

94 ffects hemocytin and astakine levels, two I. scapularis hemocyte markers, impacting blood-feeding, mo

95 rfere with B. burgdorferi colonization of I. scapularis, highlighting a specific role for OspB in spi

96 Here, we show that an Ixodes scapularis homolog of croquemort (Crq), a CD36-like prot

97 er that a toxin in blacklegged ticks (Ixodes scapularis) horizontally acquired from bacteria-called d

98 deficiency (IMD) pathway of the tick Ixodes scapularis How XIAP activates the IMD pathway in respons

99 strate p47 as a positive regulator of the I. scapularis IMD network.

100 the miRNA response of the tick vector Ixodes scapularis in response to Anaplasma phagocytophilum infe

101 in tick phenology between populations of I. scapularis in the Midwest and Northeast of the United St

102 istributed within the geographic range of L. scapularis in Wisconsin.

103 han the human biting "bridge" vector, Ixodes scapularis, in maintaining the enzootic spirochete cycle

104 ty may be associated with protection from I. scapularis-induced infection.

105 rated using a B. burgdorferi N40-infected I. scapularis infestation model.

106 Ixodes scapularis is a primary vector of tick-borne pathogens i

107 The tick Ixodes scapularis is able to feed repeatedly on its natural hos

108 Ixodes scapularis is the main vector of Lyme disease in the eas

109 In the USA, Ixodes scapularis is the main vector of tick-borne zoonoses inc

110 The deer tick, Ixodes scapularis, is a vector of the HGE agent, and the white-

111 this virus in a region where its vector, I. scapularis, is known to be prevalent or may represent th

112 ninfected and A. phagocytophilum-infected I. scapularis ISE6 tick cells, a model for tick hemocytes i

113 ls and has no known pathogenic effects on I. scapularis, its genome sequence provides insight on the

114 -1) and nine of nine mice infected by Ixodes scapularis (Ixodes dammini) tick inoculation of an isola

115 In Wisconsin and Minnesota, Ixodes scapularis (Ixodes dammini) ticks are the vector of thre

116 We demonstrate that the I. scapularis Janus kinase (JAK)-signaling transducer activ

117 The six isolates from I. scapularis lacked OspA and OspB, four possessed an OspD

118 fed on uninfected mice and in uninfected I. scapularis larvae and nymphs as they first acquired spir

119 We determined the safety of using I. scapularis larvae for the xenodiagnosis of B. burgdorfer

120 Ixodes scapularis larvae successfully acquired Bb(DeltaA66) fol

121 Xenodiagnosis using Ixodes scapularis larvae was safe and well tolerated.

122 Ixodes scapularis larvae were fed on EMLA-infected mice, and af

123 Xenodiagnostic I. scapularis larvae were fed upon each mouse at 14 and 21

124 smission with B. burgdorferi-infected Ixodes scapularis larvae.

125 iption levels through RNA interference in I. scapularis limited Kenny accumulation, reduced phosphory

126 show that a dae gene in the deer tick Ixodes scapularis limits proliferation of Borrelia burgdorferi,

127 Ixodes scapularis long-term blood feeding behavior is facilitat

128 pulating immune signaling cascades within I. scapularis may lead to innovative approaches to reducing

129 We investigated whether Ixodes scapularis-mediated host immunity interrupts transmissio

130 rate that A. phagocytophilum modifies the I. scapularis microbiota to more efficiently infect the tic

131 h 338 are reported here as putative novel I. scapularis miRNAs.

132 olated from pools of Aedes terrens and Aedes scapularis mosquitoes.

133 ith pathogen-free ticks prior to infected I. scapularis nymph challenge became positive for B. burgdo

134 Immunity acquired by mice during I. scapularis nymphal activity in early summer may exclude

135 in the metabolic profile among uninfected I. scapularis nymphal ticks, B. burgdorferi-infected nympha

136 nto the anal pore of unfed uninfected Ixodes scapularis nymphal ticks.

137 ticks after capillary inoculation of Ixodes scapularis nymphs and the subsequent spirochetal infecti

138 ression by B. burgdorferi in infected Ixodes scapularis nymphs as they fed on uninfected mice and in

139 proteins in mice after challenge with Ixodes scapularis nymphs harboring B. burgdorferi 297.

140 ted from infection when infested with Ixodes scapularis nymphs harboring virulent B. burgdorferi 297.

141 Ixodes scapularis nymphs infected with either the B. burgdorfer

142 bite and challenged 16 weeks later by Ixodes scapularis nymphs infected with either the same or the a

143 To assess vlsE expression, Ixodes scapularis nymphs infected with the B. burgdorferi strai

144 lenged either 12 or 16 weeks later by Ixodes scapularis nymphs infected with the same agent.

145 nfested four times with pathogen-free Ixodes scapularis nymphs prior to infestation with nymphs infec

146 Infected I. scapularis nymphs transmitted E. phagocytophila within 2

147 Ehrlichia-infected I. scapularis nymphs were fed upon Borrelia-infected mice,

148 elia-infected mice, and Borrelia-infected I. scapularis nymphs were fed upon Ehrlichia-infected mice.

149 optimized for I. scapularis adult ticks, I. scapularis nymphs, other tick species, and sand flies co

150 The abundance of host-seeking Ixodes scapularis nymphs, the principal vector for the Lyme dis

151 can lead to decreased feeding ability of I. scapularis nymphs.

152 glands of A. phagocytophilum-infected Ixodes scapularis nymphs.

153 f B. burgdorferi organisms within feeding I. scapularis nymphs.

154 ealed that antibody generated against Ixodes scapularis OATP cross-reacted with H. longicornis OATP.

155 Then, focusing on blacklegged ticks (Ixodes scapularis) on mice (Peromyscus leucopus), we fit the ex

156 These data indicate that bites from adult I. scapularis only rarely result in Lyme disease, and that

157 phagocytophilum specifically up-regulates I. scapularis organic anion transporting polypeptide, isoat

158 The integrity of the I. scapularis PM was essential for B. burgdorferi to effici

159 In addition, 2 of 14 larval Ixodes scapularis pools, which were attached to two PCR-positiv

160 Demographically, both Borrelia and I. scapularis populations in the Northeast show the charact

161 On the other hand, I. scapularis populations show strong regional divergence (

162 We have utilized annotations of Ixodes scapularis proteases in gene bank and version 9.3 MEROPS

163 e) represent ~1.14% of the 20485 putative I. scapularis protein content.

164 re, we show that a secreted tick protein, I. scapularis protein disulfide isomerase A3 (IsPDIA3), enh

165 tachment to the tick gut by binding to an I. scapularis protein.

166 challenging because of the vast number of I. scapularis proteins secreted during feeding.

167 nanoparticle vaccine that targets 19 Ixodes scapularis proteins.

168 st other tick sequences, ~11% (25/233) of I. scapularis putatively active proteases are conserved in

169 Identification of an I. scapularis receptor for B. burgdorferi is the first step

170 me for the Rickettsia endosymbiont of Ixodes scapularis (REIS), a symbiont of the deer tick vector of

171 Infestation of C3H/HeJ mice with infected I. scapularis resulted in an up regulation of IL-4 as early

172 burgdorferi-infected mice upregulated an I. scapularis Rho-like GTPase (IGTPase).

173 Moreover, we have found that I. scapularis saliva (dilution 1/200; approximately 10 nM P

174 s studies have demonstrated that both Ixodes scapularis saliva and Borrelia burgdorferi antigens modu

175 tanding the immunosuppressive activity of I. scapularis saliva and vector-host interactions.

176 In this study, the effects of Ixodes scapularis saliva on cytokine production by bone marrow-

177 expression of multiple anticoagulants in I. scapularis saliva would have to be ablated simultaneousl

178 scribe a feeding-inducible protein in Ixodes scapularis saliva, Salp15, that inhibits CD4(+) T cell a

179 ism for the T cell inhibitory activity of I. scapularis saliva.

180 tained the amino-terminal sequence of the I. scapularis salivary anticomplement (Isac).

181 ns that elicit antibodies in the host, an I. scapularis salivary gland cDNA expression library was pr

182 Following sequencing of an I scapularis salivary gland complementary DNA (cDNA) libra

183 a low dose of POWV, with and without Ixodes scapularis salivary gland extract.

184 Here, we sought to characterize the Ixodes scapularis salivary gland microRNAs (miRNAs) expressed d

185 icks were not able to successfully infect I. scapularis salivary glands.

186 Ixodes scapularis salivary protein 20 (Salp20) is a member of t

187 Salp15 is an Ixodes scapularis salivary protein that inhibits CD4+ T cell ac

188 ocytophilum induces expression of the Ixodes scapularis salp16 gene in the arthropod salivary glands

189 than in cognate vector populations (i.e., I. scapularis Say = I. dammini Spielman, Clifford, Piesman,

190 ubjects who presented with a definite Ixodes scapularis (Say) tick bite were measured to determine th

191 e 2.1 Gbp nuclear genome of the tick, Ixodes scapularis (Say), which vectors pathogens that cause Lym

192 vary glands of the black-legged tick, Ixodes scapularis (Say, 1821).

193 With the exception of I. scapularis, sequence variation was not observed within l

194 e and, therefore, that control of nymphal I. scapularis should be a major component of Lyme disease p

195 I. scapularis suppresses host immunity in the skin to promo

196 and a specificity of 0.86 for a bite from I. scapularis that became engorged.

197 ere we report the ability of the tick Ixodes scapularis, the main vector of Lyme disease in the Unite

198 n the Northeast, it is transmitted by Ixodes scapularis, the same vector that transmits Lyme disease.

199 larvae uninfected with the spirochete Ixodes scapularis, thereby perpetuating the agent through succe

200 Paul area in regions with known I. scapularis tick activity.

201 s following a documented bite from an Ixodes scapularis tick and the erythema migrans rash associated

202 oxycycline given within 72 hours after an I. scapularis tick bite can prevent the development of Lyme

203 ther antimicrobial treatment after an Ixodes scapularis tick bite will prevent Lyme disease.

204 mponents to estimate the frequency of Ixodes scapularis tick bites and the resulting incidence of Lym

205 continuously for over 500 days in the Ixodes scapularis tick cell line IDE8 by using the Gardel isola

206 G3 were also expressed in an infected Ixodes scapularis tick cell line.

207 d showed that A. phagocytophilum modifies I. scapularis tick cell miRNA profile and upregulates isc-m

208 The I. scapularis tick genome appears to have evolutionarily lo

209 pregulated when spirochetes leave the Ixodes scapularis tick gut, migrate to the salivary gland, and

210 The I. scapularis tick is a potential pathogen vector that can

211 f human granulocytic anaplasmosis, in Ixodes scapularis tick salivary glands, to detect proteins or g

212 c regression revealed that a bite from an I. scapularis tick that became engorged (TEI >3.4) was a ri

213 ase is transmitted by the bite of the Ixodes scapularis tick, which can also transmit Anaplasma phago

214 n, Ap-Variant 1, were obtained in the Ixodes scapularis tick-derived cell line ISE6.

215 d mice (a reservoir model) to nymphal Ixodes scapularis ticks (a biological vector) and subsequently

216 at both uninfected larval and nymphal Ixodes scapularis ticks acquired B. burgdorferi as early as 1 d

217 ant cells were able to survive within Ixodes scapularis ticks after a blood meal from naive mice; how

218 tively by sampling natural populations of I. scapularis ticks along the East Coast from 1996 to 1998.

219 Using Ixodes scapularis ticks and age-matched mice purchased from two

220 , sigma54 mutants were able to infect Ixodes scapularis ticks and be maintained for at least 24 wk af

221 intracellular pathogen transmitted by Ixodes scapularis ticks and causing human granulocytic anaplasm

222 dentified from among 99 isolates from Ixodes scapularis ticks and from white-footed mice (Peromyscus

223 gh percentages of B. burgdorferi-infected I. scapularis ticks and P. leucopus mice were common in are

224 of Borrelia burgdorferi infection in Ixodes scapularis ticks and Peromyscus sp. mice captured from a

225 e assay was tested on field-collected Ixodes scapularis ticks and shown to have 100% concordance comp

226 ammals that are frequent hosts for larval I. scapularis ticks and that are found in areas where HGE o

227 eri bbk32 and bbk50 expression within Ixodes scapularis ticks and the murine host, and the effect of

228 from inoculated C.B-17 mice to larval Ixodes scapularis ticks and, subsequently, from infected nympha

229 microti and Borrelia burgdorferi use Ixodes scapularis ticks as vector and Peromyscus leucopus mice

230 However, none of 104 mice or 713 I. scapularis ticks captured from the study sites were infe

231 I. scapularis ticks collected from other locations were fed

232 Eight isolates were made directly from I. scapularis ticks collected from white-tailed deer in Min

233 At least 17 of 697 Ixodes scapularis ticks collected in Minnesota or Wisconsin wer

234 PCR analysis of Ixodes scapularis ticks collected in New Jersey identified infe

235 fied from template DNA extracted from Ixodes scapularis ticks collected in Rhode Island and from EDTA

236 the salivary gland extract (SGE) from Ixodes scapularis ticks facilitates the transmission and dissem

237 ow that spirochetes could be found in Ixodes scapularis ticks feeding on 4 of 10 antibiotic-treated m

238 Host-seeking Ixodes scapularis ticks found in the same habitat also were inf

239 We collected 1232 Ixodes scapularis ticks from 17 east coast sites ranging from N

240 ains of DTV that had been detected in Ixodes scapularis ticks from Massachusetts in 1996 and in the b

241 We collected Ixodes scapularis ticks from regions of suspected patient tick

242 od samples: one from a goat infected with I. scapularis ticks from Rhode Island and a second from a g

243 ng 279 Powassan viruses isolated from Ixodes scapularis ticks from the northeastern United States.

244 in 482 subjects who had removed attached I. scapularis ticks from their bodies within the previous 7

245 Ixodes scapularis ticks harbor numerous human pathogens, includ

246 e importance of IAFGP for the survival of I. scapularis ticks in a cold environment.

247 ive study of such patients implicated Ixodes scapularis ticks in disease transmission.

248 lia burgdorferi, it is transmitted by Ixodes scapularis ticks in the northeastern United States and b

249 I. scapularis ticks in which ispdiA3 has been knocked down

250 hat the presence of A. phagocytophilum in I. scapularis ticks increases their ability to survive in t

251 gical risk index based upon the number of I. scapularis ticks infected by B. burgdorferi was highest

252 Here, we report that Ixodes scapularis ticks infected with either Anaplasma phagocyt

253 cytophilum strain HZ in SCID mice and Ixodes scapularis ticks infected with strain NTN-1.

254 In the United States, Ixodes scapularis ticks overwinter in the Northeast and Upper M

255 Arthopods such as Ixodes scapularis ticks serve as vectors for many human pathoge

256 paper we explore the contribution of Ixodes scapularis ticks to the pathogenicity of Borrelia burgdo

257 Ixodes scapularis ticks transmit a number of human pathogens, i

258 Ixodes scapularis ticks transmit a wide array of human and anim

259 Ixodes scapularis ticks transmit many pathogens that cause huma

260 Ixodes scapularis ticks transmit many pathogens, including Borr

261 Ixodes scapularis ticks transmit multiple pathogens, including

262 Ixodes scapularis ticks transmit the Lyme disease agent in the

263 pression within the guts of engorging Ixodes scapularis ticks was examined by use of differential imm

264 Nymphal Ixodes scapularis ticks were collected from several sites in Rh

265 Ixodes scapularis ticks were collected in 2000 and 2001 from tw

266 Laboratory-reared larval I. scapularis ticks were placed on 36 subjects and allowed

267 feri produce OspA in the gut of unfed Ixodes scapularis ticks, and many spirochetes repress OspA prod

268 conjugated to a protein expressed by Ixodes scapularis ticks, called I. scapularis antifreeze glycop

269 vel of thiamin and its derivatives in Ixodes scapularis ticks, the enzootic vector of Bb, is extremel

270 an Ixodes ricinus tick cell line and Ixodes scapularis ticks, to alter the ratio of monomeric/filame

271 ssential for the persistence of Bb in Ixodes scapularis ticks.

272 in A. americanum, Ixodes affinis, and Ixodes scapularis ticks.

273 its main vector, the northern lineage of I. scapularis ticks.

274 se and human granulocytic ehrlichiosis in I. scapularis ticks.

275 s within 210 days after attachment of Ixodes scapularis ticks.

276 ith blood from infected mice and with Ixodes scapularis ticks.

277 mammals that host immature stages of Ixodes scapularis ticks.

278 tachment for nymphal and adult female lxodes scapularis ticks.

279 for the five OspA-negative isolates from I. scapularis ticks.

280 mayonii, are transmitted primarily by Ixodes scapularis ticks.

281 sease agent, Borrelia burgdorferi, by Ixodes scapularis ticks.

282 the extracellular matrix, also exists in I. scapularis ticks.

283 bited a reduced ability to survive in Ixodes scapularis ticks.

284 or engorged Ixodes dammini (also known as I. scapularis) ticks, further supporting the postulate that

285 its paralogs also reduced the ability of I. scapularis to feed, as demonstrated by a 50-70% decline

286 Ixodes scapularis transmits the agent of human granulocytic ana

287 The black-legged tick Ixodes scapularis transmits the human anaplasmosis agent, Anapl

288 ericanum, 76 Amblyomma maculatum, 383 Ixodes scapularis, two Ixodes brunneus, and 35 Dermacentor vari

289 e range expansion of the tick vector, Ixodes scapularis, upon which the causative agent, Borrelia bur

290 me disease focus with an abundance of Ixodes scapularis vector ticks and the first documentation of H

291 naturally colonized their arthropod (Ixodes scapularis) vector, were maintained in ticks throughout

292 tus-cottontail rabbit enzootic cycle, but I. scapularis was also found to harbor a strain of this gen

293 Larval acquisition of B. burgdorferi by I. scapularis was also inhibited by BBK32 antisera.

294 Ixodes scapularis was found across the body, although it showed

295 irochete-infected nymphal deer ticks (lxodes scapularis) was developed to assess human risk of Lyme d

296 urgdorferi) and its main tick vector (Ixodes scapularis) was studied concurrently and comparatively b

297 Infected nymphal Ixodes scapularis were allowed to feed individually on mice, an

298 FPI), Ixolaris, from the ixodid tick, Ixodes scapularis, which has 10 cysteines, and a thrombin inhib

299 For example, ticks such as Ixodes scapularis, which must remain on the host for up to 7 da

300 orferi, colonizes the gut of the tick Ixodes scapularis, which transmits the pathogen to vertebrate h