ライフサイエンスコーパス: screening

1 (5 years earlier than the recommended age of screening).

2 iac disease and serve as a test bed for drug screening.

3 d improving the quality of colorectal cancer screening.

4 unds to outcomes of digital mammography (DM) screening.

5 8.5% children, 54.4% women) underwent vision screening.

6 States instead of DM alone for breast cancer screening.

7 east cancer mortality compared with stopping screening.

8 biocatalyst via ultrahigh throughput droplet screening.

9 alcifications during 20 years of mammography screening.

10 ydrophobic cavity suitable for targeted drug screening.

11 physicians are overdue for colorectal cancer screening.

12 same strain as a parental strain at time of screening.

13 strategy is for offering population-wide CRC screening.

14 ant impact of ion caging and plasma electron screening.

15 ed platform for ESI-MS-based high-throughput screening.

16 (COVID-19) serological testing and antiviral screening.

17 eated by surgery than those diagnosed not by screening.

18 erse panel of imine reductases available for screening.

19 l mapping and (19)F NMR T(2) filtering-based screening.

20 ied social cognitive determinants of retinal screening.

21 in turn, motivate their patients to undergo screening.

22 ll-child visits, HbA(1c) testing, and cancer screening.

23 ease who were referred for colorectal cancer screening.

24 the accuracy and efficiency of breast cancer screening.

25 ic CrAg-positive patients identified through screening.

26 s; 27 of 48 [56%] male) referred for cardiac screening 1.5-T MRI between 2014 and 2017.

27 The Nutrition Risk Screening-2002 (NRS-2002), Subjective Global Assessment

28 December 31, 2018, 4,247 patients underwent screening; 247 were reviewed weekly by a VIA diagnostic

29 Screening 3-monthly was cost-effective (ICER: $4,500/QAL

30 After screening 6789 articles, we included 26 studies.

31 By automated screening, 8.3% of the 180 study participants had refera

32 Screening a library of microscale reactions and selected

33 eir continued movement and introduction, but screening a sufficient fraction to ensure rare infection

34 Pooled library CRISPR/Cas9 knockout screening across hundreds of cell lines has identified g

35 II HLA molecules were selected for in vitro screening against PBMC samples from a cohort of chronic

36 dence is increasing among young adults below screening age, despite the effectiveness of screening in

37 Nontargeted (NTA) and suspect screening analyses (SSA) aim to detect and identify unkn

38 of kidney function in both preclinical drug screening and clinical settings.

39 Universal screening and convenient access to maternal health servi

40 ese features have led to many techniques for screening and diagnosis, but many are expensive, less fe

41 xist within the myriad of currently employed screening and diagnostic methods.

42 highlighting the need for effective regular screening and early intervention modalities to prevent t

43 terature on historical disparities in cancer screening and emerging evidence of disparities in LCS.Re

44 immunity and have clear implications for the screening and evaluation of novel adjuvants.

45 We used structure-based virtual screening and fragment-based drug discovery to identify

46 High-throughput screening and gene signature analyses frequently identif

47 SpyCas9), we used both self-targeting CRISPR screening and guilt-by-association genomic search strate

48 oximity of a metal, which induces additional screening and hence suppresses electron interactions.

49 blish the potential of cfDNA for lung cancer screening and highlight the importance of risk-matching

50 A compartmental model of NG/CT screening and infection was implemented.

51 hine learning to address the need for better screening and medical diagnostics in all areas of diseas

52 intestinal microbiome might be used for CRC screening and modified for chemoprevention and treatment

53 idate a patient-reported outcome measure for screening and monitoring vision-related anxiety in patie

54 Ralphabeta-Jurkat libraries enabled repeated screening and panning for antigen-reactive TCRs using pe

55 ics, suggesting their usefulness not only as screening and predictive biomarkers, but also in capturi

56 orkflow allows for rapid and high-throughput screening and quantitation of 105 veterinary drugs in ho

57 l COVID-19 disease status, the role of viral screening and serological testing, return-to-work consid

58 , and review current recommendations for CRC screening and surveillance.

59 of the number of guides depleted in library screening and the extent of the induced transcriptional

60 ates could be explained by both increases in screening and the prevalence of gonorrhea.

61 Community screening and therapeutic prevention strategies may redu

62 wering treatment for at least 4 weeks before screening and who had an LDL cholesterol level of 130 mg

63 aff represent acceptable solutions to expand screening, and (iv) whether testing a large percentage o

64 Early case detection, contact screening, and chemoprophylaxis are the most promising t

65 d gene set enrichment analysis and proteomic screening, and identified substantial reprogramming of t

66 val from TRB was not improved as a result of screening, and many false-positive results required addi

67 a Global Initiative to scale up preventive, screening, and treatment interventions to eliminate cerv

68 the laboratory assays, prospective community screenings, and healthcare seeking behaviors.

69 g the way toward T-dependent high-throughput screening applications by HDX-MS.

70 pening up the possibility of high-throughput screening applications of relevance to the biomedical an

71 tential for disease modeling and therapeutic screening applications.

72 e developed a multiplexed negative selection screening approach in which edited loci are deep sequenc

73 A strategic screening approach led to the discovery of this novel li

74 Here, we use a combinatorial screening approach to identify a bis-benzodioxolylindoli

75 re we employed a genome-wide CRISPR knockout screening approach to systemically identify the genetic

76 PR2A which enables this target for NMR-based screening approaches.

77 for computer-aided diagnosis and image-based screening are being adopted worldwide by medical institu

78 Regional epidemiology and level of active screening (AS) both influenced the predicted time to EOT

79 in both herpesvirus biology and cancer, our screening assay may be used as a platform to identify bo

80 Using a FRET-based high-throughput screening assay that we previously reported, we identifi

81 main epitope for the IgE and is suitable as screening assay to detect CHX reactivity.

82 ivity, and establishes curation of data from screening assays, used routinely in antimalarial drug di

83 We introduce a methodology for optimizing screening, assessing potential risks, and quantifying as

84 ic charges contribute to charge transfer and screening at oxide interfaces, triggering a thermodynami

85 via microscopy, establishing robust droplet screening at single-cell resolution.

86 0 000 per quality-adjusted life-year gained, screening beginning at age 30 years was preferred.

87 comparing IPTp with SP against intermittent screening by rapid diagnostic tests (ISTp).

88 to analysis and are too slow for large-scale screening campaigns.

89 Experimental testing of 62 screening candidates yielded the discovery of 10 new ago

90 s disease 2019 would allow expanding current screening capacities, thereby enabling the expansion of

91 on to the disease biology but are limited in screening capacity.

92 undesired variants that can quickly outstrip screening capacity.

93 Method for the ICU, Intensive Care Delirium Screening Checklist, a focused bedside cognitive examina

94 k assessment, counseling, and decision aids; screening checklists; community engagement; and provider

95 Comparative performance benchmarks from true screening cohorts are needed.

96 also inspire the design of future macrocycle screening collections.

97 21 RA healthy middle-aged volunteers before screening colonoscopy.

98 romising approach to improve cervical cancer screening coverage, especially among women with limited

99 We developed screening criteria to identify a subset of potential env

100 t retrospectively measured lung nodules from screening CT scans obtained between September 2016 and J

101 trumentation and will be useful for antibody screening, custom assay development, biomarker detection

102 The screening data provide a resource of immunomodulatory pr

103 Literature screening, data extraction and quality appraisal was und

104 The learnings from the 2015 screening deck were applied to the design of a next gene

105 We used a randomized phase II screening design with a primary end point of overall sur

106 s many patients with SLE are ANA negative at screening despite previously testing positive.

107 This resulted in 3156 screening-detected cancers (6.8 cancers detected per 100

108 d per 1000 screenings), of which 26 (0.8% of screening-detected cancers [26 of 3156]) were detected a

109 Approaches to prostate cancer screening, diagnosis, surveillance, treatment and manage

110 onization Group (IGHG) recommends risk-based screening echocardiograms, but evidence supporting its f

111 NA and novel biomarkers validated by aptamer screening, ELISA, and immunofluorescence microscopy.

112 hensive sexually transmitted infection (STI) screening every 3-6 months for men who have sex with men

113 ve cohort study of patients who received ROP screening examinations at a level IV neonatal intensive

114 lonoscopy completion in adults with abnormal screening fecal immunochemical test (FIT) results.

115 Screening, followed by colonoscopic polypectomy (or surg

116 ent decisions, the present evidence supports screening for and targeting of modifiable risk factors f

117 presentatives, developed a recommendation on screening for anxiety in adolescent and adult women to i

118 ted SCAD pathogenesis is noninflammatory and screening for autoimmune diseases based on SCAD alone is

119 uggest that the benefits of population-based screening for CKD are uncertain; that there is potential

120 Traditional screening for COVID-19 typically includes survey questio

121 fever >=37.5 degrees C, necessitating urgent screening for Ebola virus, and a small number developed

122 RNA-sequencing screening for factors induced by activation of Ocn-Cre(+

123 Advice by mail, screening for fall risk, and a targeted exercise or mult

124 ) recommends a domestic medical examination (screening for infectious and noninfectious diseases/cond

125 By contrast, screening for latent tuberculosis before immune checkpoi

126 Effort to raise public awareness screening for lung cancer has been ongoing.

127 rs, previously trained to undertake trachoma screening for one month, performed eye examination.

128 mation for risk-adapted starting ages of CRC screening for patients with diabetes, who are at higher

129 Furthermore, screening for suspects in LC-HRMS data resulted in the d

130 library containing nearly 4000 fragments and screening for target-specific binders within days.

131 n Malawi and South Africa (Rapid urine-based Screening for Tuberculosis to reduce AIDS Related Mortal

132 e difference was significant in favor of the screening group (hazard ratio, 0.17; 95% CI, .03-.86).

133 Among 10,232 African Americans in the early screening group who were mailed a FIT, screening was com

134 forts should be made to improve adherence to screening guidelines, especially for vulnerable populati

135 following its recent emergence, and symptom screening has become a ubiquitous tool in the global res

136 ces, even in high-income countries; and that screening has substantial opportunity costs in low- and

137 Studies are needed on the effects of screening high-risk persons and to identify quality meas

138 tified through optimization of a 6-azaindole screening hit.

139 rmine TB-LAM Ag positive) identified through screening HIV-positive inpatients with sputum and urine

140 High-throughput screening (HTS) research programs for drug development o

141 Compound screening identified a protein kinase c activator that p

142 Proteomics screening identified adenine nucleotide translocase 3 (A

143 High-throughput screening identified doxorubicin (DXR) as an inhibitor o

144 x show promise as biomarkers for anal cancer screening in HIV+ and at-risk HIV-negative women.

145 nts are not advised for cardiometabolic risk screening in large groups.

146 screening age, despite the effectiveness of screening in older populations.

147 Using comprehensive drug-sensitivity screening in PP2A-modulated cells to evaluate the functi

148 We suggest reinforcing the cancer screening in T2DM patients to enable the early detection

149 Most screening instruments are moderately to highly accurate.

150 es (n = 38 531) addressed the accuracy of 49 screening instruments to detect cognitive impairment.

151 study shows that the integration of newborn screening into existing primary health-care immunisation

152 Cervical screening involved HPV testing at age 35 years, or at ag

153 Phenotypic screening is an unbiased method to screen for novel targ

154 Traveller screening is being used to limit further spread of COVID

155 esenting approximately 40% of those for whom screening is currently recommended.

156 mains have been successful, but genome-scale screening is limited by the usual requirement of produci

157 ain; that there is potential for harms; that screening is not a wise use of resources, even in high-i

158 r contrast material administration in breast screening.Keywords: Breast, MR-Diffusion Weighted Imagin

159 Broad preoperative screening led to 1 positive COVID-19 test in an asymptom

160 with established cardiovascular disease and screening lipoprotein(a) levels of at least 60 mg per de

161 Screening mammograms were double reported.

162 tudied whether or when women can safely stop screening mammography.

163 hypothesis that chromatophores constitute a screening mechanism in O. wendtii, providing sufficient

164 broadly applicable high-throughput operando screening method for heterogeneous catalysts.

165 We have also developed a temperature-based screening method for synthetic paralysis that can be use

166 Here, we describe an arrayed CRISPR screening method, Genome engineering-based Interrogation

167 Screening methods are effective but have limitations.

168 Advances in cancer screening methods have opened avenues for incidental fin

169 The use of sensitive screening modalities for early detection of lung cancer

170 Screening of 600 Victorian clinical isolates identified

171 lase activity was isolated during functional screening of a human gut metagenomic library using Lacto

172 detected on polymerase chain reaction (PCR) screening of a large homeless shelter population in Bost

173 mp face shield (n = 57 [91.9%]), temperature screening of all persons entering clinical space (n = 34

174 expensive, promising analytical tool for the screening of both the quality and safety of ketchup samp

175 wever, only a few have their origin from the screening of combinatorial peptidomimetic library.

176 We have performed the parallel screening of commercially available compounds against a

177 developed a platform for rapid phage display screening of deep recombinant libraries consisting of as

178 Standard state-of-the-art techniques for screening of electrogenic bacteria are inefficient, and

179 ques to isolate effective compounds based on screening of entire compound libraries based on desired

180 Parallel (multichip) screening of ferric ion concentration gradients (0-40 mM

181 FTD/ALS syndromes and indicate that genetic screening of FTD/ALS patients for HTT repeat expansions

182 e that meets the need for de novo functional screening of genome-scale metabolic networks (GSMNs) at

183 e 1990s, however, indicates that low-dose CT screening of high-risk patients enables detection of lun

184 By a loss-of-function genetic screening of individual IFN-stimulated genes (ISGs) on h

185 Guidelines suggest endoscopic screening of individuals who are at increased risk for B

186 Finally automated robotized screening of low-dimensional hybrid perovskite materials

187 nce for future attempts to achieve proximity screening of many-body phenomena in two-dimensional syst

188 roposed method can be applied for an overall screening of migrants from these three simulants at even

189 APRI allows screening of NAFLD as well as fibrosis in obese patients

190 ed ex vivo stimulation of memory T cells and screening of naive and memory T cell libraries, combined

191 and open-source OPERA application to enable screening of new chemicals with a defined applicability

192 etup shows limited ability to perform a true screening of oregano using the setup offered.

193 riminatory ability of GOAL questionnaire for screening of OSA(>=5), OSA(>=15), and OSA(>=30) was simi

194 ed by a model that accounts for hydrodynamic screening of packed cilia and the chemomechanical energy

195 time to perform comprehensive and systematic screening of RNA virome in medically important mites inc

196 e searched for new agents by high-throughput screening of selected targeted compounds and identified

197 he presence of mobile ions, enabled by ionic screening of the carbon electrode.

198 Despite modest sensitivity, low-cost, repeat screening of the entire population could be cost-effecti

199 Phenotypic screening of the resulting oxazonine collection identifi

200 ected cancers (6.8 cancers detected per 1000 screenings), of which 26 (0.8% of screening-detected can

201 Screening outcome in the era of SFM (1997-2008), the tra

202 The compounds identified through our screening paradigm have the potential to be used as prop

203 r prevention interventions for women include screening, partner notification, promoting condoms, and

204 Continuing annual breast cancer screening past age 75 years did not result in substantia

205 networks, have enabled the development of AF screening pathways using the ubiquitous 12-lead ECG to d

206 s is a cost- and time-efficient approach for screening patient cohorts.

207 tial utility of the composite cTAG score for screening patients prior to biopsy to identify those sui

208 astoma, we develop a high-throughput in vivo screening platform and discover several driver variants

209 reliable and convenient ultrahigh-throughput screening platform based on flow cytometric droplet sort

210 ons prompted us to develop a high-throughput screening platform of cancer drugs in a quest to repurpo

211 lying disease mechanisms and for use as drug screening platform, particularly for reagents designed t

212 A hybrid drug screening procedure was proposed and applied to identify

213 atient companions (n = 59 [95.2%]), use of a screening process (n = 59 [95.2%]), use of a slit-lamp f

214 for Pa-positive patients with a surveillance screening program does not significantly reduce ICU-acqu

215 g contained within the National Korea Health Screening Program for Infants and Children database.

216 A surveillance screening program for Pa was implemented.

217 est set-based assessment schemes in a breast screening program has the potential to predict and ident

218 To examine the impact of a screening program to detect anal cancer precursors on th

219 Despite the existence of screening programmes worldwide, the interpretation of ma

220 of mental disorders were measured using the Screening Questionnaire for Disaster Mental Health (n =

221 terventions (n = 88) indicated higher cancer screening rates with patient navigation; telephone calls

222 rom GP databases could be used to complement screening referral decisions by identifying those at gre

223 ith challenges, including need for extensive screening, reluctance to participate, and compliance iss

224 atment and the overall cost-effectiveness of screening remains uncertain.

225 Smartphone-based fundus imaging can meet DR screening requirements in an outreach setting; however,

226 and the lower positive predictive value of a screening result compared to an indication-based testing

227 the first 60 hours of life, with a positive screening result defined as bilirubin levels exceeding d

228 Patients with positive or inconclusive screening results were referred for comprehensive ophtha

229 Chemical screening revealed that inhibition of MEK/ERK signaling

230 onal hybrid perovskite materials through the screening robot PROTEUS has emerged as a powerful tool i

231 Analogies to imaging, newborn screening, routine testing panels, and antibiotic sensit

232 portance of sample preparation for nontarget screening should be addressed.

233 ia, Germany, a program of primary care-based screening showed an islet autoantibody prevalence of 0.3

234 -low expression genes were identified at the screening step, and finally found six mostly changed hub

235 ions focused on the yield of alternative HBV screening strategies and the accuracy of tools to identi

236 t phenotypic models, as well as the chemical screening strategies most often employed.

237 lysis units and hence, assessment of current screening strategies.

238 in the development of so-called "untargeted" screening strategies.

239 ing a mathematical simulation, we examined 3 screening strategies: Yearly, 6-monthly, and 3-monthly,

240 Here, we established a screening strategy to identify drugs that reduce ACE2 le

241 Our results demonstrate the efficacy of our screening strategy, which can lead to the rapid discover

242 y of life after SAH influenced the preferred screening strategy.

243 Drug screening studies for inflammatory skin diseases are cur

244 ited cardiomyopathies have been derived from screening studies, most often of young adult populations

245 k-matching cases and controls in cfDNA-based screening studies.

246 Many centers are currently screening surgical patients for COVID-19 using either ch

247 countries, and existing programmes focus on screening symptomatic rather than asymptomatic staff.

248 ity to ototoxin in a high-content phenotypic screening system.

249 resonance imaging (AB-MR) as a supplemental screening test in women with dense breasts.

250 A model including the screening test result had a C-statistic of 0.860, c-slop

251 as led to the development of pharmacogenetic screening tests, such as HLA-B*57:01 in abacavir therapy

252 udies (n = 15 785) evaluated the accuracy of screening tests; across individual studies and tests, se

253 Lastly, when screening the link across subjects between initial varia

254 pre-clinical model will serve as a tool for screening therapeutic strategies to reduce/eliminate HIV

255 Patients underwent screening through the TECS protocol and received an FTF

256 cation of active compounds, while decreasing screening time and resources.

257 tive approach for high throughput analytical screening to discard defective cocoa samples.

258 ed approach and performed antiviral activity screening to identify compounds 29 and 30 with EC(50) va

259 we applied an unbiased approach using CRISPR screening to identify genes that strongly regulate invas

260 ll transcriptome analysis and pooled knockin screening to measure cell abundance and cell state ex vi

261 cerevisiae, which allow for high-throughput screening to patient-derived cell-lines that have a clos

262 ith the application of high-resolution omics screening to populations enrolled in large-scale observa

263 he predictive value of placental sonographic screening to predict early-onset FGR.

264 mated efficiency of population-based newborn screening to prevent ketoacidosis, and enables individua

265 positioning; we therefore used computational screening to reverse-engineer and identify these forces.

266 d by polygenic risk scoring and phenome-wide screening, to identify genetic comorbidities.

267 sk as measured by the malnutrition universal screening tool (MUST), CT derived body composition as me

268 C(4) plant, and can potentially be used as a screening tool for WUE(plant) in sorghum.

269 towards the development of an accessible PD screening tool that will passively monitor the subject-s

270 Real-time PCR was used as a screening tool with great accuracy, while internal trans

271 itional Status Index (CONUT) are widely used screening tools, but their efficacy has not yet been com

272 humanitarian crises that includes education, screening, treatment, and palliative care for refugees a

273 graphy images of IPNs from the National Lung Screening Trial, internally validated, and externally te

274 ange intervention (leaflet) on self-reported screening uptake, and previously identified social cogni

275 nerating new developments in high-throughput screening used to identify functional lncRNAs.

276 Here, we performed high-throughput CRISPR screening using a ubiquitin regulator-focused single-gui

277 he changes in gene expression and functional screening using an in vitro mouse oocyte development sys

278 COVID-19 symptoms who underwent preoperative screening using chest CT and RT-PCR before elective or e

279 Label-free high-throughput screening using mass spectrometry has the potential to p

280 cancer death between continuing and stopping screening was -1.0 (95% CI, -2.3 to 0.1) death per 1000

281 early screening group who were mailed a FIT, screening was completed by 33.1%.

282 Then, an accurate screening was successfully conducted in C57BL/6 primary

283 Here, using genome-wide screening, we find that SAT1 selectively controls nicoti

284 Using RNA sequencing and drug screening, we find that treatment of FLT3 internal tande

285 ling in vivo ribosome profiling with genetic screening, we provide direct evidence that oncogene-indu

286 vices Task Force (USPSTF) for annual CT lung screening were analysed for pulmonary nodules (PN) detec

287 The lung cancer cases diagnosed by screening were more likely to be early-staged and treate

288 Data from patients with MRSA nares screening were obtained from the VA Corporate Data Wareh

289 -old men and women (most common age of first screening), which were 0.44% and 0.41%, respectively.

290 ase their participation in colorectal cancer screening, which could, in turn, motivate their patients

291 uited from the general population to undergo screening with an implantable loop recorder.

292 Purpose To determine if screening with DBT is associated with lower FN rates, de

293 The CDR was higher for repeat screening with DBT+SM than for the control group with FF

294 Background Screening with digital breast tomosynthesis (DBT) improv

295 ) and was not significantly lower for repeat screening with FFDM (3.5 per 1000 women screened vs 4.5

296 This study used suspect and nontarget screening with high-resolution mass spectrometry to char

297 Here, we performed global metabolite screening with metabolite set enrichment coupled with tr

298 Screening with protocol biopsy was favored over biomarke

299 We next report an MS1 automatized suspect screening workflow that allows for a rapid preannotation

300 eased utilization of SFE as a part of future screening workflows of microbial natural products.