ライフサイエンスコーパス: sebaceous

1 te stem cells, accompanied by an increase in sebaceous activity, a phenotype analogous to that seen w

2 A sebaceoma and a sebaceous adenoma also showed positive results for both

3 10-6), in sebaceous carcinoma compared with sebaceous adenoma and downregulation of 2 miRNAs previou

4 altered in sebaceous carcinoma compared with sebaceous adenoma provides a novel entry point for a mor

5 the pathogenesis of sebaceous carcinoma and sebaceous adenoma remain poorly understood.

6 RNA expression profile distinct from that of sebaceous adenoma, implicating dysregulation of NF-kappa

7 10-5), in sebaceous carcinoma compared with sebaceous adenoma.

8 Thirty sebaceous carcinomas and 23 sebaceous adenomas (including 11 that were confirmed to

9 Muir-Torre syndrome involves cutaneous sebaceous adenomas and internal malignancy; screening of

10 squamous lesions but instead develop benign sebaceous adenomas containing a signature mutation in th

11 es in the development and maturation of both sebaceous and meibomian glands, as well as in the format

12 le, and required for the maintenance of both sebaceous and meibomian glands.

13 maining the same; and (2) trophic effects on sebaceous and Meibomian glands.

14 neoplastic steatogenesis is observed in both sebaceous and nonsebaceous carcinomas, the pattern and i

15 ils--as well as lacrimal, mammary, salivary, sebaceous and sweat glands.

16 We reviewed 10 cases of sporadic sebaceous carcinoma and 1 case involving a patient with

17 tical need to delineate the pathways driving sebaceous carcinoma and candidate molecules for targeted

18 erations contributing to the pathogenesis of sebaceous carcinoma and sebaceous adenoma remain poorly

19 ) and miR-184 (3.5-fold; P = 1.7 x 10-6), in sebaceous carcinoma compared with sebaceous adenoma and

20 ion of miRNAs whose expression is altered in sebaceous carcinoma compared with sebaceous adenoma prov

21 -9) and miR-518d (-4.5-fold; 6.7 x 10-5), in sebaceous carcinoma compared with sebaceous adenoma.

22 Sebaceous carcinoma exhibits an miRNA expression profile

23 immunostaining are helpful in distinguishing sebaceous carcinoma from other neoplasms with overlappin

24 Given that sebaceous carcinoma is associated with substantial morbi

25 ma correlates with outcomes in patients with sebaceous carcinoma of eyelid.

26 Sporadic sebaceous carcinoma of the ocular adnexa is not commonly

27 All 8 patients with an invasive component of sebaceous carcinoma underwent a biopsy in which the tumo

28 Sebaceous carcinoma usually occurs in adults older than

29 ipophilin immunostaining in the diagnosis of sebaceous carcinoma were both 100% when more than 5% of

30 c glass slides of 12 patients diagnosed with sebaceous carcinoma were reviewed.

31 h node surveillance for patients with eyelid sebaceous carcinoma with tumors of T category T2b or wor

32 tival melanoma, 4 squamous cell carcinoma, 1 sebaceous carcinoma, and 1 atypical pterygium.

33 atients with squamous cell carcinoma, 1 with sebaceous carcinoma, and 1 with metachronous bilateral l

34 iffuse conjunctival squamous cell carcinoma, sebaceous carcinoma, or lymphoma that had recurrent or r

35 we present clinical care recommendations for sebaceous carcinoma, which were developed as a result of

36 ignificant contributions to the diagnosis of sebaceous carcinoma.

37 ic alterations pivotal to the development of sebaceous carcinoma.

38 Nordic consensus for the treatment of eyelid sebaceous carcinoma.

39 g (target of miR-211) in the pathogenesis of sebaceous carcinoma.

40 Ten sebaceous carcinomas (8 invasive, 2 intraepithelial only

41 Thirty sebaceous carcinomas and 23 sebaceous adenomas (includin

42 Sebaceous carcinomas demonstrated significantly stronger

43 All 10 sporadic periocular sebaceous carcinomas maintained strong staining of the 4

44 ipophilin expression was observed in 100% of sebaceous carcinomas, 100% of cutaneous squamous cell ca

45 CRABP1 was similarly expressed in the sebaceous cell carcinoma and control groups.

46 Of the 16 sebaceous cell carcinoma cases reviewed, six were male a

47 beta-catenin was significantly increased in sebaceous cell carcinoma cases.

48 However, the pathoetiology of sebaceous cell carcinoma is not clear.

49 nin, RA-binding proteins and RA receptors in sebaceous cell carcinoma of the eyelid and try to estima

50 Sebaceous cell carcinoma of the eyelid is a malignant tu

51 signaling is related to the pathogenesis of sebaceous cell carcinoma of the eyelids.

52 ta, -gamma) was significantly upregulated in sebaceous cell carcinoma of the eyelids.

53 ancy (7 squamous cell carcinomas [43.75%], 5 sebaceous cell carcinomas [31.25%], and 4 malignant mela

54 idation of linoleic acid is specific for the sebaceous cells and correlates with their function and d

55 The ability of the sebaceous cells to synthesize wax esters correlated with

56 bservation was the appearance of tumors with sebaceous differentiation in the ears of Dsk5 mice after

57 thway of keratinocytes while suppressing the sebaceous differentiation pathway of skin epithelium.

58 ocytes, GATA6 triggers a junctional zone and sebaceous differentiation program whilst limiting lipid

59 ors and also defines tumors with elements of sebaceous differentiation, including a subset of basal c

60 aneous skin tumours, most of which exhibited sebaceous differentiation, which could be indicative of

61 eins localized to epidermis, hair follicles, sebaceous ducts, and sebaceous glands in sections of fac

62 ntly, the killing activity was maintained in sebaceous environments as Pentobra was bactericidal agai

63 each a Nordic consensus for the treatment of sebaceous eyelid carcinoma.

64 copy revealed preferential thermal injury to sebaceous follicles and glands, consistent with predicti

65 l cells are still unknown because almost all sebaceous follicles contain dense concentrations of bact

66 rough coat (rc) spontaneous mutation causes sebaceous gland (SG) hypertrophy, hair loss, and extracu

67 The sebaceous gland (SG) is an essential component of the sk

68 Mutations in Lef1 occur in human and mouse sebaceous gland (SG) tumors, but their contribution to c

69 Its functions in the sebaceous gland (SG), however, remain poorly characteriz

70 s: the epidermis, the hair follicle, and the sebaceous gland (SG).

71 Sebaceous gland ACC represents an attractive therapeutic

72 ing puberty are likely due to alterations in sebaceous gland activation and sebum composition.

73 transcriptional regulators of the epidermal, sebaceous gland and hair follicle differentiation progra

74 llow systematic annotation of hair follicle, sebaceous gland and interfollicular epidermal abnormalit

75 roscopy is a promising tool for studying the sebaceous gland and its associated disorders in three di

76 haft and in the most mature sebocytes of the sebaceous gland and preputial, meibomium, ceruminous gla

77 Our results suggest that the bulge and sebaceous gland are, respectively, non-permissive and pe

78 aceous unit, containing the infundibulum and sebaceous gland as independent compartments, but contrib

79 These results document sebaceous gland atrophy in nonscalp psoriasis, identify

80 Although the human sebaceous gland can synthesize cholesterol from acetate

81 melanoma (85 and 42 patients, respectively), sebaceous gland carcinoma (35 patients), squamous cell c

82 Sixteen cases of eyelid sebaceous gland carcinoma who received tumor excision at

83 mma (PPARgamma) is thought to play a role in sebaceous gland cell function.

84 An SV40 immortalized human sebaceous gland cell line (SEB-1) was established in ord

85 stearoyl-CoA desaturase in the immortalized sebaceous gland cell line SZ95 and whole skin.

86 entiation of adipocytes and are expressed in sebaceous gland cells.

87 targeted interruption of this pathway in the sebaceous gland could be a desirable approach to reducin

88 ation (Plet1, Lrig1 Lef1, and beta-catenin), sebaceous gland development (adipophilin, Scd1, and oil

89 Our findings reveal that Gata6 controls sebaceous gland development and cancer.

90 ntial involvement of the Hedgehog pathway in sebaceous gland development using transgenes designed to

91 t display striking abnormalities in hair and sebaceous gland development.

92 milar and therefore further understanding of sebaceous gland differentiation and lipogenesis and pote

93 postnatal skin, where all hair follicles and sebaceous gland differentiation are also repressed and o

94 ase-PCR (RT-PCR) and immunohistochemistry of sebaceous gland differentiation markers revealed reduced

95 hat involves an aberrant hair cycle, altered sebaceous gland differentiation with reduced sebum produ

96 a hair-loss phenotype that includes altered sebaceous gland differentiation, short hair shafts, aber

97 and lipogenesis and potential therapies for sebaceous gland disorders may be obtained from our knowl

98 gely unaffected but after an initial wave of sebaceous gland duplication sebocyte differentiation was

99 al injection is sufficient to induce ectopic sebaceous gland elements.

100 expansion of the base of the hair follicle, sebaceous gland enlargement and abnormal clumping of the

101 specific expression pattern within the human sebaceous gland for the two AWAT genes, consistent with

102 omoter during the hair/vibrissa follicle and sebaceous gland formation.

103 abis sativa, (-)-cannabidiol (CBD), on human sebaceous gland function and determined that CBD behaves

104 eatment of skin disorders linked to abnormal sebaceous gland function, such as acne.

105 ble hair in PP skin may result from abnormal sebaceous gland function.

106 ated with abnormal hair cycle, epidermal and sebaceous gland hyperplasia, hyperkeratosis, and increas

107 cluding cyclic and progressive hair loss and sebaceous gland hypertrophy.

108 and report here that SKO mice display marked sebaceous gland hypoplasia and depletion of sebaceous li

109 ion in asebia J1 and 2 J mice, with profound sebaceous gland hypoplasia.

110 The sebaceous gland is an integral part of the pilosebaceous

111 , Veniaminova et al. (2019) report that each sebaceous gland is maintained by local stem cells and th

112 nding of the molecular signaling involved in sebaceous gland lipid production is needed to develop th

113 energy homeostasis, feeding efficiency, and sebaceous gland lipid production, as well as immune and

114 um hydration, associated with a reduction in sebaceous gland lipids (wax diesters/monoesters, sterol

115 Insulin and IGF-1 stimulate sebaceous gland lipogenesis.

116 in the tail were disorganized and had excess sebaceous gland lobules.

117 reduced proliferation, and hair follicle and sebaceous gland loss in 30-d-old K5Cre beta1-null mice.

118 f histone H4 by holocrine secretion from the sebaceous gland may play an important role in innate imm

119 genesis and differentiation, but accelerated sebaceous gland morphogenesis.

120 nds and suggests that the environment of the sebaceous gland permits catalysis of the sebaceous-type

121 T1 plays an important role in normal fur and sebaceous gland physiology and provide evidence that lep

122 bacterial colonization, or the deposition of sebaceous gland products.

123 a subpopulation of cells at the base of the sebaceous gland readily formed ectopic follicles, result

124 r effect on sebocytes, the major cell of the sebaceous gland responsible for producing sebum.

125 riasis, identify a cytokine-regulated set of sebaceous gland signature genes, and suggest that loss o

126 h agonist anti-EDAR antibodies, we find that sebaceous gland size and function can be restored to wil

127 Sebaceous gland size and sebum production may serve as b

128 uroic acid significantly reduced hamster ear sebaceous gland size, indicating that this pro-drug appr

129 uced by beta-catenin arise from areas of the sebaceous gland that have lost CRABP2 and FABP5; convers

130 ls, which reside in the adult hair follicle, sebaceous gland, and epidermis.

131 m cells in the bulge can generate epidermis, sebaceous gland, and hair bulb matrix cells.

132 the majority of layers of the hair follicle, sebaceous gland, and interfollicular epidermis in a hair

133 comprising the hair follicle, an associated sebaceous gland, and overlying epidermis; however, the s

134 ate control of HS levels is required for HF, sebaceous gland, and sweat gland morphogenesis and HF cy

135 d153 were observed in the outer root sheath, sebaceous gland, dermal papilla, and connective tissue s

136 re expressed in the differentiating cells of sebaceous gland, interfollicular epidermis and hair foll

137 Forming the hair follicle-associated sebaceous gland, sebocytes are specialized lipid-produci

138 tology shows abnormal differentiation of the sebaceous gland, with the sebocytes producing little or

139 The formation of sebaceous gland-derived epithelial cysts does not fit th

140 tamin D receptor enhanced differentiation of sebaceous gland-derived hair follicles and stimulated ec

141 that regulate microbial commensalism through sebaceous gland-mediated tuning of the barrier surface,

142 omeostatic effect of Edar stimulation on the sebaceous gland.

143 ogressive transformation of the niche into a sebaceous gland.

144 opulation of fibroblasts located beneath the sebaceous gland.

145 hance the disinfecting activity of the human sebaceous gland.

146 em to form the epidermis, hair follicle, and sebaceous gland.

147 vel found in the preputial gland, a modified sebaceous gland.

148 ytes located in the suprabasal layers of the sebaceous gland.

149 air follicles, interfollicular epidermis and sebaceous gland.

150 differentiation and lipid metabolism of the sebaceous gland.

151 s demonstrated further by (i) the absence of sebaceous-gland-associated lipase activity in asebia mic

152 These results show that sebaceous-gland-derived glycerol is a major contributor

153 3 channel and from triglyceride turnover in sebaceous glands (SG) are important determinants.

154 Oil-secreting sebaceous glands (SGs) are critical for proper skin func

155 on, can be found in hair follicle-associated sebaceous glands (SGs) or in free SGs such as the Meibom

156 nocytes in the interfollicular epidermis and sebaceous glands (SGs) to differentiate along the hair f

157 K6a expression correlates with duct fate in sebaceous glands (SGs).

158 Sebaceous glands also fail to form in gamma-secretase-de

159 cles, with FABP5 being a prominent marker of sebaceous glands and anagen follicle bulbs.

160 e keratin 15 (K15) promoter and targeted the sebaceous glands and base of the follicle (bulb) with a

161 ill microbes and have been detected in human sebaceous glands and cell lines.

162 ir loss, which were associated with atrophic sebaceous glands and fur lipid abnormalities.

163 mis is modestly hypoxic and portions of some sebaceous glands and hair follicles are moderately to se

164 mulates de novo hair follicle formation from sebaceous glands and interfollicular epidermis, while on

165 of Setd8, leading to an irreversible loss of sebaceous glands and interfollicular epidermis.

166 nfined to the hair follicle, but also lie in sebaceous glands and interfollicular epidermis.

167 s and exhibited abnormal development of both sebaceous glands and meibomian glands, specialized sebac

168 In human volunteers, cooling damaged sebaceous glands and reduced sebum output for 2 weeks, w

169 r both P450c17 and steroidogenic factor 1 in sebaceous glands and SEB-1 cells.

170 as the major fatty acid desaturase in human sebaceous glands and suggests that the environment of th

171 ted the development of tumors of specialized sebaceous glands and suppressed tumors characteristic of

172 led to the morphogenesis and hyperplasia of sebaceous glands and sweat glands in mature mice, leadin

173 ge markers and contribute to hair follicles, sebaceous glands and/or epidermis renewal.

174 Importantly, the enlarged sebaceous glands are associated with an increased expres

175 eport that the interfollicular epidermis and sebaceous glands are hyperproliferative, coincident with

176 Current techniques for studying sebaceous glands are mostly static in nature, whereas th

177 ce explaining why aberrant hair follicles or sebaceous glands are sometimes observed in non-skin tiss

178 nate lymphoid cells (ILCs) and modulation of sebaceous glands by a subset of RORgammat(+) ILCs residi

179 ands, implying that selective destruction of sebaceous glands could be an effective treatment.

180 CARS microscopy revealed dynamic changes in sebaceous glands during the holocrine secretion process,

181 These ectopic sebaceous glands expressed molecular markers of sebocyte

182 of glycerol generation from triglyceride in sebaceous glands for stratum corneum hydration was demon

183 og signaling also triggered the formation of sebaceous glands from footpad epidermis, in regions norm

184 or phenotypes--irregularities of hair cycle, sebaceous glands hypoplasia, and a thinner epidermis--po

185 In normal sebaceous glands IHH is expressed in differentiated sebo

186 Sebaceous glands in all skin regions respond to treatmen

187 ifferentiated epidermis, hair follicles, and sebaceous glands in an in vivo environment.

188 Sebaceous glands in Fatp4 null skin grafted onto nude mi

189 dermis, hair follicles, sebaceous ducts, and sebaceous glands in sections of facial skin.

190 nt upper hair follicle immediately below the sebaceous glands in the follicle bulge.

191 irradiation to thermally disrupt overactive sebaceous glands in the skin which define the etiology o

192 delivered into human pre-auricular and swine sebaceous glands in vivo, using mechanical vibration.

193 Studies in sebocytes and human sebaceous glands indicate that agonists of peroxisome pr

194 ing in complete and reversible conversion of sebaceous glands into hair follicles.

195 Selective cryolysis of sebaceous glands is achievable through brief, non-invasi

196 Our findings suggest that absence of sebaceous glands is an early step in KP pathogenesis, re

197 Inhibition of ACC activity in the sebaceous glands is designed to substantially affect seb

198 The only known function of human sebaceous glands is the provocation of acne.

199 This study demonstrated that while sebaceous glands may be involved in hair eruption, they

200 BD-2, was also observed in the hair follicle sebaceous glands of mouse ear skin after an epicutaneous

201 esions are seen in the nail and nail bed and sebaceous glands of PC and SM patients, respectively.

202 ous glands and meibomian glands, specialized sebaceous glands of the eyelids.

203 s of endogenous Lef-1 expression seen in the sebaceous glands of vibrissa and hair follicles in trans

204 Sebaceous glands perform complex functions, and they are

205 plied onto Yorkshire pig ears accumulated in sebaceous glands relative to the surrounding dermis.

206 conclude that interfollicular epidermis and sebaceous glands retain the ability to be reprogrammed i

207 ynthase mRNA was abundant in tissues rich in sebaceous glands such as the preputial gland and eyelid

208 ternative-the in vivo, label-free imaging of sebaceous glands using Coherent Anti-Stokes Raman Scatte

209 teroidogenic factor 1 in SEB-1 sebocytes and sebaceous glands was compared to mRNA levels in ovarian

210 A1 transgenic mice was unaffected, but their sebaceous glands were hypertrophied and hyperplastic, co

211 Sebaceous glands were markedly atrophic in PP versus non

212 At 22 wk, new cartilage, hair follicles, and sebaceous glands were observed in the newly generated ti

213 Klf5CN eyelid hair follicles and sebaceous glands were significantly enlarged, and the me

214 inability to reconstitute hair follicles and sebaceous glands when grafted onto mice, but epithelial

215 hells in inducing photothermal disruption of sebaceous glands without damaging collateral skin.

216 ndages (hair follicles, apocrine glands, and sebaceous glands) for wound repair in model animals, the

217 of follicular orifices, striking absence of sebaceous glands, and hair shaft abnormalities in KP les

218 n substitutes formed pigmented hairs without sebaceous glands, and human-only skin substitutes formed

219 itted progenitors, formation of hypertrophic sebaceous glands, and increased epidermal differentiatio

220 pendages, such as hair, teeth, sweat glands, sebaceous glands, and mammary glands, requires the actio

221 nd hyperkeratosis, severe hyperplasia of the sebaceous glands, and structural alterations of hair fol

222 t; eosinophilic necrotic plugs formed within sebaceous glands, and the number of glands was significa

223 ducts, and glands such as sweat, mucous and sebaceous glands, are initiated in development as placod

224 licle and a series of associated structures: sebaceous glands, arrector pili muscles, Merkel cells, a

225 The phenotypic effects of mEDA-A1 on sebaceous glands, but not on hair follicles, were revers

226 y skin substitutes formed external hairs and sebaceous glands, chimeric skin substitutes formed pigme

227 tures in the skin of a live mouse, including sebaceous glands, corneocytes, and adipocytes, with unpr

228 ted complete regeneration of hair follicles, sebaceous glands, dermis and cartilage.

229 rbing microparticles could be delivered into sebaceous glands, enabling local injury by optical pulse

230 Follicles were complete with sebaceous glands, hair shafts and inner and outer root s

231 hysiology of acne vulgaris depends on active sebaceous glands, implying that selective destruction of

232 l skin cooling causes preferential injury to sebaceous glands, in murine and swine models using a ran

233 tative product of triglyceride hydrolysis in sebaceous glands, normalized stratum corneum hydration,

234 ice develop mild alopecia and hyperplasia of sebaceous glands, particularly around the eyes.

235 oteins examined in vitro around comedones or sebaceous glands, providing solid evidence for suggested

236 llicles, interfollicular epidermis (IFE) and sebaceous glands, revealing a remarkable ability of the

237 nd WNT10B, and downregulation of a marker of sebaceous glands, Steroyl-CoA desaturase.

238 g identified copiously in hair follicles and sebaceous glands, suggesting a potential route of exit a

239 n affected tissues including hair follicles, sebaceous glands, taste buds, nails and sweat ducts.

240 expansion of the sebocyte-producing zone in sebaceous glands, with particularly high expression of t

241 within hair follicles in close proximity to sebaceous glands.

242 icles in prolonged telogen with hyperplastic sebaceous glands.

243 epithelial structure with hair follicles and sebaceous glands.

244 on with reduced effects in the uterus and in sebaceous glands.

245 g reduced effects on reproductive organs and sebaceous glands.

246 ir follicle distensions adjacent to enlarged sebaceous glands.

247 cle orientation, and increased expression of sebaceous glands.

248 entification of histamine receptors in human sebaceous glands.

249 te a stratified epidermis, hair follicles or sebaceous glands.

250 ation program from forming hair follicles to sebaceous glands.

251 -induced abnormalities in hair follicles and sebaceous glands.

252 egenerate new hair follicles, epidermis, and sebaceous glands.

253 terfollicular epidermis, hair follicles, and sebaceous glands.

254 heart, dermis, atrophic hair follicles, and sebaceous glands.

255 striking increase both in size and number of sebaceous glands.

256 er-root sheath cells, and basal cells of the sebaceous glands.

257 as nerves, vasculature, hair follicles, and sebaceous glands.

258 expression was abundant in keratinocytes and sebaceous glands.

259 ed total lipoatrophy and complete absence of sebaceous glands.

260 /Delta) mice and likely were due to the lack sebaceous glands.

261 n-specific kinase expressed predominantly in sebaceous glands.

262 mented hair follicles that are equipped with sebaceous glands.

263 get heated, and induce focal thermolysis of sebaceous glands.

264 errantly expressed in the tumor cells of the sebaceous glands.

265 rticles enable selective photothermolysis of sebaceous glands.

266 0.25, 44.4-fold) and strongly upregulated in sebaceous hyperplasia (fold change > 4, 54.1-fold).

267 Consequently, loss of ILCs resulted in sebaceous hyperplasia with increased production of antim

268 The intersection of PP-downregulated and sebaceous hyperplasia-upregulated gene lists generated a

269 Survey for linear nevus sebaceous Jadassohn was negative.

270 known to maintain epidermal, follicular and sebaceous lineages during homeostasis.

271 gnaling pathways that determine squamous and sebaceous lineages, respectively.

272 oliferator-activated receptors (PPARs) alter sebaceous lipid production.

273 m, particularly lipase-mediated breakdown of sebaceous lipids and release of irritating free fatty ac

274 idermal lipids are lacking, the relevance of sebaceous lipids in health and disease remains poorly un

275 seful for further investigating the roles of sebaceous lipids in skin and eye integrity.

276 phtheria chain A toxin-mediated depletion of sebaceous lipids resulted in impaired water repulsion an

277 which account for approximately 25% of human sebaceous lipids, are unique in that they are not synthe

278 sebaceous gland hypoplasia and depletion of sebaceous lipids.

279 genes, defects frequently observed in human sebaceous neoplasia.

280 Sebaceous neoplasms (SNs) define the Muir-Torre syndrome

281 combining molecular genetic features of the sebaceous neoplasms, including microsatellite instabilit

282 Examination revealed a multilobulated sebaceous nodule protruding from the nasal tip.

283 In a human sebaceous organoid model GATA6-mediated down-regulation

284 The sebaceous phenotype of SEB-1 sebocytes was confirmed usi

285 ch as keratinocytic epidermal nevi and nevus sebaceous result from somatic mosaicism.

286 Because children have less sebaceous skin before puberty, we compared the fungal co

287 The most common sebaceous skin commensal yeasts are the basidiomycetes,

288 ceptor staining also was performed on benign sebaceous tumors (a sebaceoma and an adenoma) and as con

289 PTCH is up-regulated in both human and mouse sebaceous tumors and is accompanied by overexpression of

290 We found that one-third of human sebaceous tumors examined had double-nucleotide substitu

291 rogen receptors and adipophilin can separate sebaceous tumors immunohistochemically from squamous car

292 Furthermore, reactivating AP-1 in sebaceous tumors results in a reciprocal transdifferenti

293 They developed sebaceous tumors, whereas controls developed squamous ce

294 minus of LEF1 is frequently mutated in human sebaceous tumors.

295 d squamous tumors to transdifferentiate into sebaceous tumors.

296 ermine the differentiated characteristics of sebaceous tumors.

297 ta-catenin signaling, results in spontaneous sebaceous tumors.

298 the sebaceous gland permits catalysis of the sebaceous-type reaction and restricts catalysis of the p

299 acid type" reaction, but also an unexpected "sebaceous-type" reaction, that of converting palmitate i

300 inflammatory disorder of the cutaneous pilo-sebaceous unit.