ライフサイエンスコーパス: second

1 an emit thousands of oral fluid droplets per second.

2 eter and measure 3D blood flow at 99 volumes/second.

3 lysis at a speed of more than one sample per second.

4 and by 53.3% (range, 30.4%-67.8%) after the second.

5 exhibits fluorescence detection of SM within seconds.

6 1'-N-methyl with an ethyl group or adding a second 1'-N-methyl group significantly reduced interacti

7 A second 10 min "empty bladder" rs-fMRI scan was conducted

8 Five patients also underwent a second (18)F-FGln study 4-13 wk after initiation of ther

9 V) after the first (30% vs 18.8%, p = 0.15), second (20.0% vs 14.6%, p = 0.33) and third vaccination

10 transposase and terminal sequences, while a second 3131 bp element, hopper(Bd-we), isolated from a w

11 Second, a self-administered survey was distributed to AG

12 n assessed in a held-out test set and then a second academic medical center.

13 between 2009 and 2015 were enrolled from the Second Affiliated Hospital of Zhejiang University School

14 ZNF281 is recruited to DNA lesions within seconds after DNA damage through a mechanism dependent o

15 time after probing (>=15 seconds versus <15 seconds after probing versus spontaneous).

16 rpolarization, and remain in their state for seconds after stimulation.

17 identified the LITAF-like protein CDIP1 as a second, alternative receptor.

18 hematopoiesis persistence in predisposing to second AML.

19 Second, among 1,460 patients with suspected sepsis (seps

20 arches, and HOXA2, which is expressed in the second and more posterior branchial arches.

21 es occur in which the adult willow tits rank second and the hierarchy is less steep, or linear.

22 clinician capillary refill time, alternating second and third digits.

23 economic status and lifestyle factors in the second and third generations accounted for all of the in

24 Results were similar for second and third-trimester vaccination and for analyses

25 centrations (25, 50, and 80 mug/NmL), for 30 seconds and 1 minute.

26 analyses to increase temporal resolution to seconds and explore transient configurations of motor ne

27 sampling simulated odorants on the order of seconds, and provides the most information when animals

28 ing affinity can produce TKI resistance, and second- and third-generation TKIs largely mitigate this

29 ified in the mEndoG structure accommodates a second arm of a junction.

30 The second barrier comes from the intensive computing time f

31 Second, beryllium-7 is a product of cosmic rays which ar

32 man and FT-IR spectral features obtained the second best performance (R(2)CV-0.97, RMSECV-0.38 mg/g;

33 Inconclusive results prompted the need for a second biopsy in 18 patients: 13 of 125 (10.4%) in the C

34 ed, with additional protection achieved by a second bolus after the induction procedure.

35 ted with the same direction of effect in the second brain tissue (BA25, N = 60) from the same individ

36 Second, by utilizing its inherent phase stable character

37 oplasm (MPN) are prone to the development of second cancers, but the factors associated with these ev

38 troduction of a catalyst, which introduces a second catalytic cycle into the metabolic network, was u

39 st cancer is the most common cancer, and the second cause of cancer-related deaths (after lung cancer

40 Here we describe a second class of local excitatory inputs to granule cells

41 The second cohort included 28 Parkinson's disease and 43 con

42 mer's disease = 20, control = 20), then in a second cohort where the IWG-2 biomarker criteria were ap

43 Different second-component polymers are introduced to change the p

44 A second, cooperating genetic hit is often required to pus

45 In contrast to the uncinate, GFA of a second corticolimbic projection, the hippocampal cingulu

46 l correlations in cell-cycle duration, up to second cousins, seem paradoxical because ancestral corre

47 The second criterion was not applied to a subset of particip

48 The hypothesis that water has a second critical point at deeply supercooled conditions w

49 showed the lowest caproate production in the second cycle (4.10 +/- 0.30 g/L).

50 In the second cycle, AS microbiome was enriched toward caproate

51 obtained between the time of arrival and the second day of supervised quarantine and on days 7 and 14

52 Colorectal cancer (CRC) is the second deadliest cancer in the US due to its propensity

53 First- or second-degree blood relatives of a patient with ovarian

54 eligible relatives (598 first-degree and 119 second-degree relatives), 60% attended genetic counselin

55 sitive history of breast cancer in first- or second-degree relatives.

56 We sought to provide the second description of human SMARCD2 deficiency and the f

57 highest median magnitude detected after the second dose of vaccine.

58 In timeframes beginning 30 days post-second dose, the primary endpoint (overall vaccine effic

59 106 PBMCs at D30, with no increase after the second dose.

60 rate that the 2000-2018 SWNA drought was the second driest 19-year period since 800 CE, exceeded only

61 trial fibrillation or flutter of at least 30 seconds duration confirmed by rhythm strip or 12-lead EC

62 Second, E449K accelerates the dissociation of non-produc

63 Second, efforts have been made to understand "what" the

64 The AMC009 trimer resembled one from a second elite neutralizer, AMC011, in having a dense and

65 utilized for the EMR+ procedure, allowing a second endoscopic device to be used through the AWC whil

66 nalyzed the effects of drought- mortality on second-entry burn emissions and compared emissions for t

67 ns and compared emissions for the first- and second-entry burns.

68 absent when the same cue was presented in a second environment.

69 However, the second enzyme (designated CsGA1ox/ds) performed multiple

70 The second episode, however, was milder and characterized by

71 hael acceptor, followed by the addition of a second equivalent of the nucleophile to this and, finall

72 conformational changes on the time scale of seconds, examining the relationship between these events

73 Remarkably, methylation of the second exon of HR4 is not only reduced in ago4-1 but als

74 In a second experiment, this time where an experimenter provi

75 The second eye was more likely to be treated earlier and to

76 of patients with a refractive outcome in the second eye within 1.0 dioptre from the target refraction

77 We report a second family with 2 siblings with a homozygous frameshi

78 ors near 3,400 cm(-1), however, occur with a second feature, which indicates that OH stretch excitati

79 was defined as forced expiratory volume in 1-second (FEV1)/forced vital capacity (FVC) ratio <0.7.

80 19(th) 20(th) 21(st) of June, 2016 while the second field measurements were taken on 14(th) 15(th) 16

81 Second, filgotinib suppresses HIV-1-driven aberrant canc

82 peak and area under the curve for 30 and 60 seconds from DSC MRI were associated with local malignan

83 e for alanine is encoded by alaT, although a second gene, dat, can support slow growth of an L-alanin

84 Here, we show that a second-generation amino-acyl tRNA synthetase (aaRS)/tRNA

85 Despite the development of second-generation antiandrogens, acquired resistance to

86 Herein, we report the discovery of second-generation GluN2C/D-selective NMDAR-positive allo

87 s of oncolytic PVs, including development of second-generation parvoviruses with enhanced oncolytic a

88 g reads can be corrected by the high-quality second-generation sequencing (SGS) short reads, which is

89 A second-generation series improved on affinity by incorpo

90 A second group of participants performed a reaching task u

91 In the second growing season of treatment, the shrub warming re

92 atives, the decision-maker can even report a second guess that is clearly informed by the sensory evi

93 or asking for confidence ratings only in the second half of the experiment.

94 rth's crust-are excluded owing to their weak second harmonic generation (SHG) response.

95 strated via polarized Raman spectroscopy and second-harmonic generation maps of the PdSe(2) flakes.

96 inst cancer [ImmTAC] molecules), whereas the second harnesses an antibody-based format (TCR-mimic ant

97 been linked to increased susceptibility to a second heat stroke, infection and cardiovascular disease

98 The process is completed within seconds, holding great potential for high-throughput ana

99 After the second immunization, serum neutralizing activity was det

100 activates pre-emptive protection against the second impending challenge.

101 timing of implantation from the first to the second implantation allowing for examination of potentia

102 e implant, without the expense and risk of a second implantation.

103 Remarkably high risks for second in situ squamous cell carcinoma of the skin were

104 Second, in marine systems, shallow subtidal and intertid

105 Second, in the streptozotocin model of hyperglycemia-ind

106 In the second independent study, tuberculosis occurred in none

107 Second, infection has been associated with multiple dire

108 Second, intentional teaching plays a greater role in CTC

109 e prioritized rs7198799, a common SNP in the second intron of the CDH1, as the putative causal varian

110 The second involves an intramolecular mechanism for q modula

111 -the-person database called MIT-BIH, and the second is one less uncontrolled off-the-person type data

112 n the number of voxels in the tumor, and the second is total lesion glycolysis (TLG), which is the TL

113 Second, it is of great importance for archaeological sci

114 In patients with a nondominant LAD, a second ITA grafted to a less important artery was associ

115 ar regardless of degree of importance of the second ITA target-77% at 15 years (p = 0.70) for the imp

116 In the multivariable model, grafting the second ITA to multiple important targets was associated

117 l study did not show better outcomes after a second IVIg course in GBS with poor prognosis.

118 from the first kidney provided by EVNP, the second kidney was not perfused with EVNP and was directl

119 This method was repeated for a second larger set to build prediction and classification

120 reenhouse gases, and the U.S. is the world's second-largest steel consumer.

121 introduces a paradox which goes against the second law of thermodynamics that states how entropy mus

122 vely scattered photons without violating the second law of thermodynamics.

123 The Lightning Network is a so-called second-layer technology built on top of the Bitcoin bloc

124 tomated sample preparation, an ultra-fast 84-second LC-MS method, and barcoded nanopore sequencing to

125 Breast cancer is the second leading cause of cancer-related death in women an

126 one in every nine men in the USA and is the second leading cause of cancer-related death.

127 Stroke is the second leading cause of death worldwide and a leading ca

128 However, stroke remains the second leading cause of death worldwide and the number o

129 05 tetramer to identify the unfurling of the second lectin ring which enables tetramer formation.

130 , similarly detected by both radiotracers, a second less intense positive focus was detected in 4 pat

131 tive AR signaling and will respond to potent second-line antiandrogen therapies, including bicalutami

132 ry by 25 percentage points, and switching to second-line ART by 1 percentage point compared with stan

133 Patients receiving second-line chemotherapy followed by resection had signi

134 to endorse the remaining recommendations for second-line chemotherapy, as well as other recommendatio

135 n of nivolumab + ipilimumab as an option for second-line therapy and third-line therapy is discussed.

136 lecular mechanism of resistance and to guide second-line therapy.

137 and it is now considered standard of care as second-line treatment for patients with recurrent/refrac

138 abozantinib with best supportive care in the second-line treatment of advanced hepatocellular carcino

139 forms due to alternative splicing, while the second major mechanism-RNA editing due to post-transcrip

140 deaths were NLPHL related (n = 10), whereas second malignancies (n = 20) and nonmalignant conditions

141 The second mechanism centers on the vulnerability of the mal

142 Our studies reveal that the second mechanism is operative.

143 intracellular application of IBMX or of the second messenger cAMP via the patch pipette had no effec

144 verts guanosine triphosphate to an important second messenger cGMP.

145 in V. cholerae is regulated by the bacterial second messenger cyclic dimeric guanosine monophosphate

146 Ca(2+) is a fundamental second messenger in all cell types and is required for n

147 cyclic guanosine-3',5'-monophosphate, a key second messenger in cell signaling and tissue homeostasi

148 tic intermediate and a multifunctional lipid second messenger produced at several discrete subcellula

149 hat degrades cA(4), a cyclic oligo-adenylate second messenger produced during the type III CRISPR imm

150 ng of NucC trimers to a cyclic tri-adenylate second messenger promotes assembly of a NucC homohexamer

151 acid (PA), which has been proposed to play a second messenger role in immunity.

152 that increases in cAMP, a critical cellular "second messenger," may be linked to changes in cellular

153 enhanced phospho-activation of TCR kinases, second-messenger generation, and JAK/STAT or NFAT transc

154 2+) and cAMP and demonstrate that astrocytic second messengers are regulated in a temporally distinct

155 TIPE proteins are carriers of lipid second messengers.

156 In the second method, we observe the changes that occur simulta

157 Populations in Mongolia from the late second millennium B.C.E. through the Mongol Empire are t

158 A second model is trained on remaining lifespan to generat

159 elling the nacreous shell layer, whereas the second module orchestrates the transport of both ions an

160 (diss) ~ 17 and ~ 31 muM), but binding of a second molecule of profilin is negatively cooperative, w

161 Cholangiocarcinoma (CCA) is the second most common malignancy arising in the liver.

162 Parkinson's disease is the second most common neurodegenerative disease after Alzhe

163 ease (PD) is a multifactorial malady and the second most common neurodegenerative disorder, character

164 neous squamous cell carcinoma (cuSCC) is the second most common skin cancer and commonly arises in ch

165 of increased river discharge, explained the second-most variation in PicoP abundance (15.9%).

166 f parental surveys of these domains from the second Newborn Sequencing in Genomic Medicine and Public

167 nclusive tests were more often referred to a second noninvasive test (stress: 14.6% versus 8.5%, odds

168 A second novel sub-type, i.e., Type II cells (64% of total

169 ority of Gulf War Veterans are overweight, a second objective was to determine if a high fat diet (HF

170 The second objective was to evaluate whether preclinical mut

171 iations in 46 neonates who were scanned on a second occasion.

172 tional models involving vector addition, the second of which included terms for the influence of past

173 The second one is RP- HPLC.

174 Two phenotypes fill into the second one: single-NSAID-induced urticaria/angioedema/an

175 ntained to ensure uniform flux distribution; second, one may mimic nature to fabricate patterned poro

176 ) spectra can now be obtained in a matter of seconds, opening up the possibility of high-throughput s

177 lar glaucoma in the right eye was seen for a second opinion after parental refusal of enucleation.

178 ite template RDV is compromised, providing a second opportunity to inhibit replication.

179 Adalimumab was prescribed as a second or greater biotherapy line in 76 patients who sho

180 eration cephalosporin, 4097 (27%) received a second or third-generation cephalosporin, and 4971 (33%)

181 The polymerization kinetics show a second order rate law, first order in both propylene oxi

182 The second order rotating frame imaging (RAFF), monoexponent

183 s from being dominated by a first order to a second order term within a range determined by the polym

184 c studies carried out with TEMPO-H(D) reveal second-order behavior, k(H) = 0.5, k(D) = 0.08 M(-1) s(-

185 esence of PNHM/Fe(3)O(4)-40 following pseudo-second-order kinetics (R(2) > 0.97) and equilibrium isot

186 ted amplification through the recruitment of second-order neurons boosts nociceptive encodings at int

187 Second-order neurons project rostrally to pathways assoc

188 e of female groups included relatively fewer second-order nodes and contained hubs.

189 c-field induced Kerr rotation(5-7) and giant second-order non-reciprocal optical effects(8) in antife

190 In an in vivo model of second organ reflow injury, we found that RvD5 did not r

191 A second orthogonal DNA binding site identified in the mEn

192 , as well as in those forecasting a possible second outbreak.

193 extraction time (low=0 versus high grade=97 seconds, P<0.001) and median laser pulsations delivered

194 tation of this CMBCD model is the subject of second part of this JACC State-of-the-Art Review.

195 The second patient was homozygous for a frameshift variant (

196 Second, people interpret feelings, like ease of processi

197 icians spent an average of 16 minutes and 14 seconds per encounter using EHRs, with chart review (33%

198 gene MLST with 100% accuracy in less than 10 seconds per isolate.

199 nd by reduced local per capita income in the second period.

200 ate during the first pulse, flows during the second perpendicular pulse, and then returns to a pinned

201 Within the second phase of polymer growth, opened hGBP1 molecules c

202 We showed that the first and second phase of RhoA activity are dependent on p63 and C

203 The patient is currently in the second phase of treatment without gastrointestinal and j

204 ed from four hPSC lines exhibited first- and second-phase dynamic glucose-stimulated insulin secretio

205 sification results in this work is ranked at second place in the testing phase of the 2019 CPM-RadPat

206 ere, we present Physcomitrella patens as the second plant system, besides Arabidopsis thaliana, with

207 ntaining two distinct ncAAs at the first and second positions, an initial step towards producing comp

208 slows the inactivation and deactivation of a second potassium conductance, G(K(LV)) .

209 he initial antenatal visit in their first or second pregnancy (n=1 393 346).

210 ined additional dendritic branches, formed a second primary dendrite, acquired more mushroom spines,

211 ing is proposed to involve the exposure of a second proteolytic site (S2'), cleavage of which is requ

212 In the second protocol, sensitized animals were fed HEWP for 28

213 of the dimer inhibits phosphorylation in the second protomer, leading to ~50% phosphorylation of the

214 Kinetic studies point to the second protonation event as being rate-determining.

215 Here, we demonstrate the isolation of a second purinergic receptor, P2K2, by complementation of

216 e) of a new vibrational coherence along this second reaction coordinate in a mode associated with the

217 males after 114.9 +/- 81.1 vs 65.4 +/- 64.3 seconds, respectively, p < 0.00001).

218 cales, that is, from the femtoseconds to the seconds, reveal that the charge carrier lifetimes as wel

219 Second, reward-paired cues are powerful motivators and t

220 ntries) and 245 surgeons (10 countries), the second-round response rates were 61% and 85% respectivel

221 om 415 maize hybrids evaluated in 4 years of second season field trials for the traits grain yield, n

222 a THz-video (32 x 32 pixels at 6 frames-per-second), shown in real-time, using a single-pixel fiber-

223 Conditional analysis revealed a second signal indexed by rs6838021 (P = 5.75 x 10-17).

224 .8 x 10(-6) frequency, while survival due to second-site maternal-effect suppressors occur at a ~10(-

225 by low temperature, CFTR-targeting drugs and second-site revertant mutation R1070W.

226 h using a longer wavelength, resulted in the second-stage morphology exhibiting termination of lamell

227 least 1 order of magnitude greater than the second-stage rate, associated with bilayer formation, in

228 There were no therapy effects on the second standardised co-primary outcome (Comprehensive Ap

229 bilayers proceeds in two steps, with a slow second step occurring over many days where native lipid

230 acid dehydratase (ALAD), which catalyzes the second step of heme biosynthesis, is an Fe-S protein.

231 In a second step, three-way arrays have been generated for ea

232 In a second step, we selected the best performing model that

233 Subsequently, IST1 assembles a second strand on CHMP1B, further constricting the membra

234 r parallel NAAT of OS and NPS samples in the second study, McNemar's test indicated that the differen

235 licate the benefits of the intervention in a second study.

236 European/North American isolates, while the second sublineage primarily consisted of African and Aus

237 Using LITAF-deficient cells, a second, subsequent whole-genome CRISPR-Cas9 screen ident

238 r some of these molecules to pop out of this second subunit before finally re-entering to form a stab

239 ta for intracranial volume between first and second surgery).

240 ging and diffraction instrument IMAT, at the second target station of the pulsed neutron and muon sou

241 The second TC incidence was also lower for those age >= 30 y

242 onstriction under a magnetic field and, at a second temperature, could grip and transport a cargo.

243 with 1 mm spatial resolution and 1 frame-per-second temporal resolution.

244 ed in a shorter time with CBG (median = 54.0 seconds) than the time required for chemomechanical agen

245 ing behaviors after the mass extinction, and second, that these persisting behaviors include deep tie

246 Second, the model is biologically validated using multip

247 son who initiates PrEP must not seroconvert; second, there should be no more than one period at high

248 Our data support an important role for the second threonine of the SF signature sequence in the U-t

249 milar attachment rates between the first and second tick feeding.

250 therapy were then randomly assigned (1:1) a second time to either indefinite maintenance or 2 years

251 conformational states interconverting on the second timescale.

252 e an accessible overview of phyllotaxis, and second to argue that the spiral patterns in plants are p

253 ratio of forced expired volume in the first second to vital capacity (FEV1:FVC) less than 0.70 with

254 her-order cortical regions took more than 10 seconds to align.

255 ly distinct signaling responses ranging from seconds to minutes.

256 Second, to what extent do findings about sacrificial dil

257 ation by PfAP2-G requires interaction with a second transcription factor, PfAP2-I.

258 Second trimester maternal plasma alpha-T concentration w

259 t to the facial skin of human fetuses in the second trimester of development.

260 lines were generated by isolating first and second trimester placental villous cytotrophoblasts foll

261 Women were randomized during their second trimester to blinded weekly doses of placebo or 4

262 We performed similar analyses with maternal second trimester tocopherol isoform levels.

263 red to women with a normal pregnancy, in the second trimester.

264 ptomic changes were shared across first- and second-trimester exposures, including for the top differ

265 -3 (n-3) and omega-3 (n-6) PUFAs measured in second-trimester plasma; n-6/n-3 ratios were calculated.

266 Upon infection, paramyxoviruses cause a second type of membrane fusion, cell-cell fusion (syncyt

267 Second, using the class label probabilities output by ou

268 ic adverse events were more common after the second vaccination, particularly with the highest dose,

269 ped clade C Env binding antibodies after the second vaccination, with higher total IgG titres after t

270 Second, vanadate was tested as a possible foliar Pi trac

271 We identified a second variant in FAF1 in the validation cohort (c.254G>

272 olish Society of Neurology (PTN) present the second version of the recommendations for examinations r

273 rsus line/drop) and time after probing (>=15 seconds versus <15 seconds after probing versus spontane

274 y rates peaked 2 wk later, coinciding with a second warming event with extreme R(onset) The epizootic

275 In the second wave of synthetic biology, the simple circuits, c

276 was a subset of individuals recruited in the second wave of the MIDUS project completed in 2009.

277 Second, we change the pH relative to the isoelectric poi

278 Second, we demonstrate that the direction and amplitude

279 Second, we evaluated our ED/PS as a stand-alone unit whe

280 Second, we expand the taxonomic breadth of tool use to i

281 Second, we find evidence of a segregation effect, since

282 Second, we find that optimal performance of a MAC with b

283 Second, we find that over-expression of an upstream or d

284 Second, we highlight data indicating that differential m

285 e same type of test cells for all reporters; second, we implemented a parallel detection of reporter

286 Second, we need a better mechanistic understanding of ho

287 Second, we propose a mechanism for privacy-preserving sh

288 Second, we quantitatively test model against multiple le

289 across very divergent organisms, and in the second, we show how the heterogeneity of autism mechanis

290 Second, we showed that PTP1B (13)C-methyl group side cha

291 Second, we used two-step MR to investigate whether DNA m

292 lam (0.025 mg/kg, N=23), provided during the second week of a 5-week outpatient regimen of motivation

293 e increased to 8.5% (5.9-11.4, n=469) in the second week, to 10.9% (7.9-14.4, n=577) in the third wee

294 Second, when implemented, indigenous property rights red

295 Second, when Xist is conditionally deleted in epithelial

296 n protein-spiked buffer, serum, and urine in seconds with excellent sensitivity (urine LOD = 0.023 g/

297 xhibited very rapid binding (in the order of seconds) with Human Salivary alpha-amylase (HSA) and Por

298 a short distance (<0.5 m) in a fraction of a second, with large angular variations due to the complex

299 our grafting approaches in the first and the second year during flowering stage.

300 esponses from 347 of 808 eligible first- and second-year adult nephrology fellows were examined (resp