ライフサイエンスコーパス: second primary cancer

1 with cancer types (first cancer, recurrence, second primary cancer).

2 cancer, of whom 1,088 were diagnosed with a second primary cancer.

3 -up (mean: 4.7 years), 279 women developed a second primary cancer.

4 risk factors to reduce risk of developing a second primary cancer.

5 d cancer recurrence, and 57 (2%) developed a second primary cancer.

6 a strong suggestion of an increased risk of second primary cancers.

7 id conditions such as obesity, diabetes, and second primary cancers.

8 intent radiation therapy is the induction of second primary cancers.

9 , of which 1243 (33.2%) were obesity-related second primary cancers.

10 virus-related, and hormone-related first and second primary cancers.

11 The highest cumulative incidence of second primary cancer 10 years after diagnosis was obser

12 eath, and hazard ratios (HRs) and 95% CIs of second primary cancer adjusted for sex, age and year of

13 egarding the long-term incidence and risk of second primary cancer after radiotherapy vs nonradiother

14 respectively) and recipients who developed a second primary cancer after transplantation (aHRs, 1.01;

15 of patients with cancer recurrence and/or a second primary cancer after transplantation are unknown.

16 examines the risk factors and predictors of second primary cancers after being diagnosed with neuroe

17 The most common second primary cancer among people with a first primary

18 r Registry were used to evaluate the risk of second primary cancers among a retrospective population-

19 Little is known about the causes of second primary cancers among individuals with a history

20 odels were used to estimate the incidence of second primary cancer and death, and hazard ratios (HRs)

21 y in 75 trials yielded rate ratios (RRs) for second primary cancers and cause-specific mortality and

22 eriods of follow-up, the AER for deaths from second primary cancers and circulatory causes increased

23 f the excess number of deaths observed while second primary cancers and circulatory deaths together a

24 s of childhood cancer, excess mortality from second primary cancers and circulatory diseases continue

25 erall survival, contralateral breast cancer, second primary cancer, and clinical bone fracture.

26 imary outcomes are breast cancer recurrence, second primary cancer, and death.

27 atients with multiple gene abnormalities had second primary cancers, and an additional patient had mu

28 ndary cancers, including metastatic cancers, second primary cancers, and cancers of unknown primaries

29 Distant metastases, second primary cancers, and deaths before LRR were censo

30 tients died of recurrent cancer, two died of second primary cancers, and four died of other causes.

31 Second primary cancers are an important cause of morbidi

32 revious history of malignancy, recurrent and second primary cancers are infrequent after renal transp

33 osure confers equally high relative risks of second primary cancers as first primary cancers.

34 surveillance and screening for recurrence or second primary cancers, assessment and management of lon

35 for breast cancer recurrence, screening for second primary cancers, assessment and management of phy

36 Ten long-term CR patients developed second primary cancers: breast (3), ovary (2), pancreas

37 the radiotherapy cohort had a higher risk of second primary cancer compared with those in the nonradi

38 lated from 2 months until the diagnosis of a second primary cancer, death, loss to follow-up, or Dece

39 is not associated with an increased risk of second primary cancers, either solid or hematologic, and

40 to <25), there was 15% increased risk of any second primary cancer for those who had overweight (25 t

41 set of patients alive, recurrence-free, and second primary cancer-free (disease-free survival [OS|DF

42 S-mutated tumors were more likely to develop second primary cancers (HR = 2.76, 95% CI, 1.34 to 5.70;

43 RCA1, BRCA2, and ERCC2 to the development of second primary cancer in breast cancer survivors, provid

44 ry breast cancer will subsequently develop a second primary cancer in the contralateral breast.

45 ing should be offered to women who develop a second primary cancer in the ipsilateral or contralatera

46 However, the incidence of a second primary cancer in transplanted patients has never

47 The risk of a second primary cancer in women treated for early invasiv

48 gated the absolute and relative incidence of second primary cancers in a large cohort of Danish cance

49 kewise, retinoids prevent the development of second primary cancers in head/neck and lung cancer pati

50 Do second primary cancers in humans arise from radiation-in

51 a first primary melanoma, 23.7% developed a second primary cancer, including 12.7% who developed a s

52 1.48), with greater risk for obesity-related second primary cancers, including a 40% increased risk f

53 The cumulative incidence of second primary cancer increased over time from 6.3% (95%

54 break-induced senescence as the mechanism of second primary cancer initiation, with clinically releva

55 erstanding the absolute risk of developing a second primary cancer is important to guide patient surv

56 agents are well-known and where the risk of second primary cancer is small.

57 and factors associated with development of a second primary cancer (melanoma versus other) after diag

58 A second primary cancer more than 1 year after prostate ca

59 Diagnosis of a second primary cancer more than 1 year after prostate ca

60 iscontinuation in 6 patients (6%) because of second primary cancers (n = 4) and infection (n = 2).

61 Second primary cancers occurred in 18 patients who recei

62 Thirteen second primary cancers occurred.

63 sis showed a 10-year cumulative incidence of second primary cancers of 12.1% (95% CI, 9.6 to 14.9) af

64 3.9%) participants received a diagnosis of a second primary cancer, of which 1243 (33.2%) were obesit

65 Main outcomes included a second primary cancer or an obesity-related second cance

66 an 1 year after diagnosis, (4) occurrence of second primary cancer or death within 1 year or less aft

67 By March 15, 2005, 394 events (recurrent, second primary cancer, or death before recurrence) had b

68 tic recurrence at other sites, occurrence of second primary cancer, or death resulting from noncancer

69 ed as time from randomization to recurrence, second primary cancer, or death.

70 mary cancer should be carefully screened for second primary cancers, particularly for cancers that ar

71 gically targetable, they open the avenue for second primary cancer prevention.

72 It is unclear whether second primary cancer risk varies by radiotherapy type.

73 We investigated the incidence of a second primary cancer (SPC) in 7,636 patients who underw

74 y survivorship (~3 years postdiagnosis) with second primary cancer (SPC) risk among 533 endometrial c

75 Second primary cancer (SPC) risks after breast cancer (B

76 e past are at increased risk of developing a second primary cancer (SPC), including second primary br

77 Second primary cancers (SPCs) are becoming a common canc

78 data for racial and ethnic disparities after second primary cancers (SPCs) are lacking despite the gr

79 in penile and vulvar/vaginal cancers and in second primary cancers (SPCs) following these cancers ar

80 t investigating the distribution and risk of second primary cancers (SPCs) in multiple myeloma (MM) s

81 d radiotherapy were more likely to develop a second primary cancer than patients who did not receive

82 Although 64 747 women developed a second primary cancer, the absolute excess risks compare

83 ed in the rates of treatment-related deaths, second primary cancers, thromboembolic events, and perip

84 The next most common second primary cancer types were prostate, breast and co

85 The incidence of second primary cancers was 3.1 per 100 patient-years in

86 Cohort identification and information on second primary cancers was obtained from the Danish Canc

87 ent-free survival (with events that included second primary cancers) was significantly improved with

88 hough the incidence and risk of developing a second primary cancer were low, it is important to discu

89 en radiation exposure and risks of first and second primary cancers were quantified using Poisson reg

90 urvivors are at increased risk of developing second primary cancers, with lung cancer being the most