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1 indicated that the enhancement of stimulated secretion by 0.1 ng/ml IL-1beta was mediated by the NF-k
3 r reduction also decreases SP-stimulated TNF secretion by 30% (P < 0.05), suggesting an interaction b
4 50% (P < 0.001), and ST2 siRNA decreases TNF secretion by 30% (P < 0.05), when stimulated by SP and I
5 oss in people with obesity decreased insulin secretion by 35% even though insulin sensitivity did not
8 receptor antagonists and siRNA inhibits TNF secretion by 50% (P < 0.001) when stimulated by SP and I
9 tibody for IL-33 receptor, ST2, inhibits TNF secretion by 50% (P < 0.001), and ST2 siRNA decreases TN
11 n by 2.6-fold and 4.3-fold respectively, and secretion by 60% (from 1208.1 +/- 186 to 1934.4 +/- 135
12 ATPase activity reduced only N249Q/R345W F3 secretion (by 62%), demonstrating this variant's unique
14 kHz and 27.1 mT significantly increased SEAP secretion by ~ 82% relative to control cells, with lesse
18 ue to interruption in a balance between CCL2 secretion by a variety of cells and its uptake by consti
19 have now been shown to contribute to protein secretion by A. baumannii and other pathogenic species o
22 essin (AVP)-stimulated cAMP levels and Cl(-) secretion by ADPKD cells than inhibition of PDE1, and in
23 ed HDL (rHDL) attenuated IFN-gamma and IL-17 secretion by Ag-specific T cells upon stimulation of dra
24 egulatory molecule controlling mucus granule secretion by airway epithelial cells as well as directed
26 e ELISA revealed detectable amounts of SEl-K secretion by all isolates, with the highest secretion le
27 e that pancreatic Hhip gene inhibits insulin secretion by altering islet integrity and promoting Nox2
28 yltransferase and the stimulation of protein secretion by altering the activity of signal peptidase I
30 c concentrations of insulin inhibit glucagon secretion by an indirect (paracrine) mechanism mediated
31 4 hours decreased glucose-stimulated insulin secretion by approximately 30% without affecting ATP syn
32 exposure, there is a decrease in angiogenin secretion by ARPE-19 cells, which was abrogated with a b
33 endent release of ATP triggering bicarbonate secretion by astrocytes via activation of metabotropic P
35 in negatively regulating pancreatic insulin secretion by augmenting COX-2-dependent PGE2 production.
36 (+) CD4(+) T helper cells to induce antibody secretion by autologous naive B cells, higher frequencie
40 and cellular senescence in promoting insulin secretion by beta cells and in regulating normal functio
41 though glucose is known to stimulate insulin secretion by beta cells, whether it directly engages nut
43 ndoplasmic reticulum stress enhanced exosome secretion by beta-cells; induced exosomal release of the
46 udies reveal that PITPNC1 promotes malignant secretion by binding Golgi-resident PI4P and localizing
49 stimulated NLRP3-dependent interleukin-1beta secretion by bone marrow-derived macrophages by activati
51 ets, since Ex-4 treatment stimulated insulin secretion by both juvenile and adult human beta cells.
53 dicates that the negative regulation of BDNF secretion by C5L2 correlates with C5aR activation and it
55 contrast, in IL-1beta-deficient mice, IL-12 secretion by CD11b(+) DCs prevails and supports antitumo
56 thermore, hyperlipidemic serum enhanced IL-6 secretion by CD1b+ DCs and increased IL-17A production b
57 mma and tumor necrosis factor-alpha cytokine secretion by CD4(+) T cells and antibody production pred
58 mportantly, CHQ-treated MoLC promoted IL-17A secretion by CD4(+) T cells and elevated RORC mRNA level
61 ut instead they specifically stimulate IL-10 secretion by CD4+ T cells and efficiently mediate PSA-af
66 T expression, and subsequent lower melatonin secretion by cholangiocytes, was associated with increas
73 of disruption by antibiotic treatment since secretions by commensal bacteria modulate primary to sec
74 accompanied by the combination of lower IL-2 secretion by conventional CD4(+) T cells, increased IL-2
75 role in mediating glucose-stimulated insulin secretion by coupling metabolic signals to beta-cell mem
78 ound that mHtt in astrocytes impairs exosome secretion by decreasing alphaB-crystallin, a protein tha
79 een proposed that glucose regulates glucagon secretion by decreasing the conductance of either outwar
80 lodextrin also blocked ATP release and IL-33 secretion by decreasing the level of VDAC-1 expression i
81 tly induces inflammatory cytokine (TNFalpha) secretion by dendritic cells, and TNFalpha secretion is
82 n response sensor IRE1alpha supports protein secretion by deploying a kinase-endoribonuclease module
86 s a hub molecule during collagen folding and secretion by directing other molecules to reach their ta
88 (Th) 1 differentiation and interferon-gamma secretion by donor T cells, which is critical for inhibi
89 hanisms underlying the inhibition of insulin secretion by dopamine, which is synthesized in pancreati
90 re, TGF-beta1/ATM-initiated paracrine factor secretion by dysfunctional renal epithelium promotes int
92 escued the Golgi structure and reduced Abeta secretion by elevating alpha-cleavage of the amyloid pre
98 strate that nGO-PEG indeed provokes cytokine secretion by enhancing integrin beta8-related signalling
101 SP-A also decreased TNF-alpha and CXCL10 secretion by ex vivo-cultured human aMvarphis and M-CSF-
103 suggest that oxytocin can modulate prolactin secretion by exciting TIDA neurons, and that this may se
106 e augmentation of glucose-stimulated insulin secretion by FA and 8-Br-cAMP in G-protein-coupled recep
108 We demonstrated that the decrease in insulin secretion by fenofibrate and Wy14643 is accompanied by r
109 pithelial cell invasion is stimulated by the secretion by fibroblast of diffusible signaling molecule
110 OX-2 inhibitor celecoxib abrogates prolactin secretion by fibroblasts and reduces tumor initiation.
114 IL-33-treated mice, IL-33 then induces IL-13 secretion by group 2 innate lymphoid cells and enteroid
116 pletely abrogated TLR2-induced interleukin 8 secretion by HEK-293 cells in response to cSSSI pathogen
117 is pivotal for inflammasome-induced IL-1beta secretion by hematopoietic macrophages, microglial secre
121 in a striking 10-fold increase in IFN-gamma secretion by HIV-1-specific CD4 T cells that is not obse
123 xpression and regulation may affect glucagon secretion by human alpha-cells in response to SGLT2 inhi
127 ly reduces lambda-light-chain production and secretion by human plasma cells regardless of sequence d
129 risk allele showed greater induction of IL-6 secretion by hydrogen peroxide or benzo[a]pyrene diolepo
131 evels of interleukin 10 and interferon gamma secretion by IEL, compared with injection of anti-CD3 on
138 this study, we assessed rhythms of cytokine secretion by immune cells and tested their response to s
140 es NGSIS, but not glucose-stimulated insulin secretion, by increasing mitochondrial proton leak.
141 h causes the repression of hydrolytic enzyme secretion by industrially relevant filamentous fungi.
142 ungus suppresses interleukin-1beta and IL-18 secretion by inhibiting both canonical and non-canonical
143 in WAT decreases leptin mRNA expression and secretion by inhibiting cAMP response element binding (C
147 till debated autocrine regulation of insulin secretion by insulin/insulin-like growth factor (IGF) 2-
148 t that microbiota dysregulation promotes LIF secretion by intestinal epithelial cells (IECs) in a mou
150 ulted in enhanced proliferation and cytokine secretion by keyhole limpet hemocyanin-experienced CD4(+
152 omponents promotes p40 protein synthesis and secretion by LGG and enhances LGG-stimulated protective
153 Tomosyn causes an attenuation of insulin secretion by limiting the formation of the SNARE complex
154 endarterectomies and an analysis of protein secretion by lipid-loaded human vascular smooth muscle c
161 found that a lack of IL-10, particularly its secretion by M s, compromised the recovery of SI epithel
163 ockade were associated with reduced cytokine secretion by macrophages in response to LPS and CLP, ult
164 ly impairs tumor necrosis factor (TNF)-alpha secretion by macrophages induced by Saccharomyces cerevi
166 DPSC/I-DPSC-mediated inhibition of TNF-alpha secretion by macrophages was abolished by pretreatment w
167 rgely reflecting increased type I interferon secretion by malignant cells and direct stimulation of i
168 ve signaling loop HK-1 promoted TNF and IL-6 secretion by MC degranulation and protein synthesis, the
169 gingivalis can dampen eATP-induced IL-1beta secretion by means of its fimbriae in a purinergic P2X7
170 primary effector pathway that modulates K(+) secretion, by metering sodium delivery to the collecting
171 thermore, we show that BM components require secretion by migrating macrophages (hemocytes) during th
174 hese findings suggest that constitutive CCL2 secretion by monocytes and other cell types is counterac
176 serotype 2 (DENV-2) elevates mature IL-1beta secretion by monocytes independent of DENV replication b
177 ular DNA to trigger proinflammatory cytokine secretion by monocytes, in a STING- and inflammasome-dep
181 ESAT-6 stimulated significantly higher IL-6 secretion by murine bone marrow derived macrophages (BMD
183 their proinflammatory cytokine and ferritin secretion by negatively regulating Erk1/2 and p38 activa
184 hibitors PP2 and dasatinib reduced chemokine secretion by neutrophils and bone marrow-derived macroph
185 eted mice, we examined LPS-induced chemokine secretion by neutrophils and macrophages in wild type an
186 s, ATP-induced P2X7R activation and IL-1beta secretion by neutrophils likely has a significant, wide
188 ments demonstrated that regDC curb IFN-gamma secretion by NK cells through a dominant suppressive mec
190 o play roles in skeletal tissues through its secretion by osteoblasts, chondrocytes, and mesenchymal
193 reefold increase in the basal rate of proANP secretion by Pam (Myh6-cKO/cKO) myocytes was a major con
194 proteins and COPI vesicle formation, proANP secretion by Pam (Myh6-cKO/cKO) myocytes was unaffected.
195 lays an important role in regulating protein secretion by pancreatic acinar cells, as does Rab3D.
196 transporter 2 (SGLT2) inhibitors in glucagon secretion by pancreatic alpha-cells reported controversi
198 A variety of signals finely tune insulin secretion by pancreatic beta cells to prevent both hyper
202 inhibition preserved glucose-induced insulin secretion by pancreatic microislets and viability of pri
205 ring RNA in DSCCs enabled increased IFNgamma secretion by PBMCs, whereas transfection of pCMV6-XL4/hP
207 rization of the in vitro dynamics of insulin secretion by perifused fragments of 10 human insulinomas
208 a, immune cell composition, ex vivo cytokine secretion by peritoneal cells or bone marrow derived mac
210 at thrombus formation is associated with PDI secretion by platelets, that inhibition of PDI blocked p
211 inimal change disease, we observed localized secretion by podocytes of hyposialylated Angptl4, a pro-
212 r mechanisms responsible for excess cortisol secretion by primary adrenal lesions and adrenocorticotr
215 (rhIL-15) synergistically enhanced cytokine secretion by proliferating HIVGag-specific CD8 T cells.
216 ed that Barr1 enhanced SU-stimulated insulin secretion by promoting SU-mediated activation of Epac2.
217 ons can dynamically control the capacity for secretion by promptly changing the number of plasma memb
218 on, decreased antiinflammatory growth factor secretion by proximal epithelial cells, and a subsequent
221 Regulation of Nischarin-mediated exosome secretion by Rab14 seems to play an important role in co
222 enriched in astrocytes and mediates exosome secretion, by reducing the association of Sp1 with the e
224 ipin 5 (PLIN5) in beta-cells aids PP insulin secretion by regulating intracellular lipid metabolism.
226 s the selective decrease in amyloidogenic LC secretion by remodeling the endoplasmic reticulum proteo
228 y, and induction of proinflammatory cytokine secretion by S. Paratyphi A but not by S. Typhimurium, s
229 ucture of MTM and PKM and their simultaneous secretion by S. venezuelae bring about the possibility t
231 ormal airways compensate for MCT-driven H(+) secretion by secreting HCO3(-), a process which is dysfu
232 y in pancreatic beta-cells decreases insulin secretion by selectively degrading insulin granules.
233 effects related to inhibition of creatinine secretion by selonsertib confounded eGFR differences at
235 pose tissue-derived factors regulate insulin secretion by silencing a pair of inhibitory neurons that
236 n of tumor necrosis factor-alpha (TNF-alpha) secretion by single monocytes in septic shock patients,
238 ts but not healthy donors show enhanced MMP1 secretion by smooth muscle cells and tumor cell invasion
239 nal part of the fusion complex that promotes secretion by SNARE interactions as well as concerted lip
240 activation, pyroptosis and interleukin-1beta secretion by soluble and crystalline Nlrp3 stimuli.
243 ides, human IAPP induces macrophage IL-1beta secretion by stimulating both the synthesis and processi
245 ate resistance to RAF inhibitors through HGF secretion" by Straussman and colleagues, published in Na
246 between MM and stromal cells increased IL-8 secretion by stromal cells through cell-cell adhesion an
247 -ATPase, abolished dopamine-induced salivary secretion by suppressing fluid transport in type III aci
250 antigens that induce interferon gamma (IFN-) secretion by T cells from immune women could advance vac
254 The myosin domain of Mcs1 enhances polar secretion by tethering vesicles at the site of exocytosi
255 a-interferon and tumor necrosis factor alpha secretion by Th1 cells, and 3) increased monocyte-mediat
257 nce of ASCs 1) enhanced interleukin (IL)-17A secretion by Th17 cells, 2) inhibited gamma-interferon a
259 l alloproliferation, inhibition of IFN-gamma secretion by the allostimulated T cells, and, conversely
261 llenged mice revealed induction of IFN-gamma secretion by the CD4 and CD8 T cells compared with non-i
263 the role of this integrin in controlling the secretion by the epidermis of factors that modulate the
266 of rapamycin's inhibitory effect on IL-1beta secretion by the IL-1 receptor antagonist anakinra in ph
268 reticulum (ER) to the Golgi determines their secretion by the liver and is mediated by a specialized
269 l for caspase-1 autoproteolysis and IL-1beta secretion by the NLRC4, NLRP3 and AIM2 inflammasomes.
270 humans and pigs lacking CFTR, unchecked H(+) secretion by the nongastric H(+)/K(+) adenosine triphosp
271 ile GLP-1 is well known to stimulate insulin secretion by the pancreatic beta-cells, direct evidence
272 ence of native AVR3a is cleaved off prior to secretion by the pathogen and the N terminus of the matu
273 prolonged preservation of endogenous insulin secretion by the remaining beta cells in patients with n
274 absorption in Henle's loop and for potassium secretion by the stria vascularis in the inner ear.
284 l polarization resulted from decreased IL-12 secretion by Treg-DC, which may be post-transcriptionall
285 of Treg function and suggest that chemokine secretion by Tregs is a fundamental aspect of their ther
286 nhibits vascular endothelial growth factor A secretion by tumor cells, inducing cancer cell apoptosis
289 ors and downstream signaling to induce their secretion by up-regulating the organic anion transporter
291 liferation, autophagy, apoptosis and insulin secretion by using mice with conditional (betaraKO) and
292 he electrical dynamics that underlie insulin secretion by utilizing a microwell-based aggregation met
295 can be released from cells: first, classical secretion by virtue of the N-terminal signal peptide; se
296 well as mineral imbalance stimulate exosome secretion by VSMCs, most likely by the activation of sph
298 ntless (Wls), a gene required for Wnt ligand secretion by Wnt-producing cells, specifically in the ha