ライフサイエンスコーパス: selection

1 , perceptual categorization, and attentional selection.

2 action with the sex-specific costs of sexual selection.

3 mage, suggesting a prominent role for sexual selection.

4 ping (usual care) to guide antiplatelet drug selection.

5 l of P450-based resistance in the absence of selection.

6 erapy has led to a Darwinian model of clonal selection.

7 enhanced sensory processing prior to target selection.

8 ise trends implicating the action of natural selection.

9 ry beyond a view, is an artifact of stimulus selection.

10 bstitution models, including models of codon selection.

11 n in the magnitude, but not the direction of selection.

12 opens up additional flexibility in precursor selection.

13 rs that may promote mate encounters and mate selection.

14 d also providing key insight for therapeutic selection.

15 s difference may have been driven by natural selection.

16 of cancer cell evolution driven by Darwinian selection.

17 eir salience, facilitating their attentional selection.

18 genome-wide association studies and genomic selection.

19 asure TE accumulation in the near absence of selection.

20 ising new directions in the study of natural selection.

21 accine effectiveness (VE) and vaccine strain selection.

22 putative mechanism for Polycomb target site selection.

23 ch is consistent with the action of negative selection.

24 y the cabbage root flies in their host plant selection.

25 s of accurate parameter estimation and model selection.

26 ow that ORF-Y is subject to strong purifying selection.

27 about long-term divergence in the absence of selection.

28 of genomic variants responding to artificial selection.

29 a significant cause for inefficient aptamer selection.

30 genomic process with parallels to Darwinian selection.

31 d risk estimates for better prevention trial selection.

32 hibiting significant signatures of balancing selection.

33 ve PVR were determined by univariate feature selection.

34 cant improvement in the inference of natural selection.

35 etaliatory strategy being favored by natural selection.

36 ncient polymorphisms maintained by balancing selection.

37 re elimination technique applied for feature selection.

38 inding by HpNikR is driven by conformational selection.

39 sts optimizing their compounds for candidate selection: (1) What are the important clearance mechanis

40 In understanding external selection, a classic distinction is made between volunta

41 vironment and develop models of their action selection across exploration and hunting.

42 est reveals that the strength of stabilizing selection acting on mRNA levels in a species is strongly

43 oaches is improving our understanding of how selection acts on key floral traits in taxonomically div

44 n size changes and the strength of purifying selection affect patterns of variation at "neutral" site

45 This opens up a new perspective on how selection affects patterns of variability at linked site

46 tolerance was still enforced, and there was selection against B cells with high affinity for self-an

47 The consistent selection against early (small) and late (large) migrant

48 ntigen receptor (VNAR) was used for in vitro selection against recombinant human TfR1 ectodomain (rh-

49 ckly eliminated after hybridization and that selection against the minor species genome might be simi

50 Benign selection agents serve as alternatives to antibiotics, w

51 y were extracted and optimized using feature selection algorithm and machine learning, from which the

52 Simulation result indicates that HD-based selection algorithm is effective in recognizing key feat

53 rho0) recipient cells following uridine-free selection, although exogenous mtDNA is lost from metabol

54 olution location data and an integrated step-selection analysis to evaluate caribou, moose, bear, and

55 g the phage clones before and after affinity selection and aligning the sequences of the most enriche

56 phabeta limits cell disposal during negative selection and confers heightened sensitivity to experime

57 while the LCI variants may be under tighter selection and consequently their distinct 3' UTR isoform

58 from the feasibility study, to the dam site selection and construction phase.

59 input time windows, algorithms of attribute selection and correlation analysis can help improve the

60 er revealing the neural mechanism of sensory selection and distractor suppression.

61 ectly in the process of evolution by natural selection and drives the evolution of cell-level interac

62 The selection and firing of DNA replication origins play key

63 vide new insights into A3 enzyme target site selection and how A3 mutagenesis impacts mutation rates.

64 ls, dendritic cells, or macrophages; patient selection and immunosuppression mirrored the RGT, except

65 population estimation could improve ES site selection and increase surveillance sensitivity.

66 Appropriate patient selection and low risk of fetal demise with FAV are crit

67 S that also displays a signature of positive selection and may have implications for tissue or cell-s

68 led classification based on distinct feature selection and modeling strategies.

69 Appropriate selection and monitoring of anticoagulants remains a cri

70 luate caribou, moose, bear, and wolf habitat selection and movement behaviour in response to anthropo

71 Backward selection and multivariate logistic regression were cond

72 nset and peaking at ~800 ms, around response selection and production.

73 filing joint chondrocytes, revealing ancient selection and recent constraint and drift on knee regula

74 stigate the within-host relationship between selection and the stochastic effects of genetic drift, e

75 C class II-restricted presentation, negative selection, and increased Treg cells, resulting in a dimi

76 alled sssHD to achieve stable sparse feature selection applied it to complicated class-imbalanced dat

77 The evaluation of our fragment selection approach was conducted using an enhanced versi

78 Scale-free networks and strong selection are generally detrimental to the performance o

79 ions known to guide overt and covert spatial selection are influenced by peripheral visual forms.

80 precise details regarding deamination target selection are not fully understood.

81 We used stability selection as an alternative computational approach to id

82 We therefore reveal sexual selection as an important force behind lineages facing e

83 precipitation that also carry signatures of selection based on F(ST) scans and PCAdapt, which repres

84 dom forests classifier and performed feature selection based on measuring permutation importance agai

85 ding strategy, and developed a group feature selection-based deep sparse neural network model (DNN-GF

86 eration batteries are limited by electrolyte selection because high ionic conductivity and poor elect

87 Selection behaviors have been studied under several inte

88 The genomic regions under selection between cattle breeds significantly overlap re

89 number of these loci also shown to be under selection between water buffalo breeds.

90 analyzing results, and (5) the potential for selection bias and other issues inherent to being unblin

91 results highlight a critical need to address selection bias in integrative analysis and to use cautio

92 l research in this area, including extensive selection bias, the use of noncompositionally robust mea

93 There is evidence of purifying selection but little evidence of diversifying selection,

94 area increased the importance of homogeneous selection, but reduced the importance of variable select

95 We seek evidence of recent positive selection by identifying loci with unusually strong shar

96 re we provide structural insight into target selection by SCF-FBXL17, a dimerization-quality-control

97 Our experiments show how selection can enhance evolvability by enhancing robustne

98 Feature selection can improve the accuracy of machine-learning m

99 rounding extracorporeal membrane oxygenation selection, cannulation, and management are applied.

100 imum of the likelihood surface, for both the selection coefficient and the allele age, to a one-dimen

101 le age, to a one-dimensional search over the selection coefficient only.

102 rate ratios of the recombination rate to the selection coefficient, the simple approximation can be s

103 r approach can deliver accurate estimates of selection coefficients, and the addition of genetic reco

104 el selection was guided by backward stepwise selection conducted on the model containing all variable

105 ic with D. setosum and D. savignyi, positive selection could arise from avoidance of maladaptive hybr

106 We included studies according to predefined selection criteria and assessed their quality according

107 vities, a comprehensive review with rigorous selection criteria has never been performed.

108 Study selection, data quality assessment, and interpretation o

109 f available prey, with implications for prey selection, demonstrating how humans perturb ecological p

110 ts demonstrate that amplification of natural selection depends on the specific mechanisms of the evol

111 d success in handling the challenge of decoy selection despite some issues associated with clustering

112 jor unresolved challenges residing in target selection, development of robust biomarkers for response

113 ws is on the rise, and that ideological self-selection does not explain most of that coexposure.

114 ng the possibility that it is under positive selection due to malaria.

115 tabases, patient cohort selection, procedure selection, duration of follow-up, statistical analysis,

116 that gaze dynamics play a key role in action selection during challenging visuomotor behaviors and ma

117 ssential role in T lymphocyte maturation and selection during development of one arm of the mammalian

118 ding loops, which are usually under negative selection during primary B cell development.

119 al control programs, including natural enemy selection, efficacy testing and quantification of non-ta

120 ignored, which could further improve feature selection efficiency.

121 itate the analysis and interpretation of arm selection events.

122 re for two weeks via a multi-step resistance selection experiment.

123 eed site randomized genomes and evolutionary selection experiments, we found that tropism could be re

124 The results demonstrate that selection favorably altered temporal dynamics of plant p

125 Natural selection favored reduced thermal reaction norm slopes a

126 critical steps, such as preprocessing, data selection, feature extraction, classification and model

127 ion preferences in eukaryotic genomes and by selection following integration.

128 Selection for a promiscuous enzyme activity provides sub

129 tate cancer biomarkers geared toward patient selection for active surveillance, identification of cli

130 A growing body of research demonstrates selection for AMR likely occurs at environmental concent

131 ion by distance combined with the effects of selection for antimalarial drug resistance.

132 this study will improve and simplify patient selection for COA intervention and potentially improve l

133 omosome 6, consistent with admixture-enabled selection for enhanced adaptive immune response.

134 Employing a quasivirus infection model and selection for G418 resistant genomes, we demonstrated th

135 axial respiratory constraints, combined with selection for novel mammalian behaviours in Late Triassi

136 s identified could help improve marker-based selection for pancreas disease resistance.

137 However, whether selection for species recognition systematically increas

138 Here we describe how selection for specific mutations that increase HSC compe

139 ore tumor resection is essential for patient selection for surgery and is conventionally done with a

140 mplification could be solely due to positive selection for the tumor-promoting effects of amplified g

141 ng these clinical parameters for better case selection for these procedures.

142 lantable recurrence (NTR) to improve patient selection for upfront LR or LT at initial diagnosis.

143 tion, but reduced the importance of variable selection, for soil bacterial community assembly within

144 indicates that MBCs emerge through unbiased selection from NBCs.

145 our model to estimate parameters of HGT and selection from our experimental evolution data.

146 In all environments, selection gradients on survival and fertility decrease w

147 eed not directly translate into variation in selection gradients, because their impact can be buffere

148 In addition, homogeneous selection has higher correlations with drought and plant

149 t the population structure ceases to amplify selection if the mutant fitness advantage r is larger th

150 oxygenation management encompassing patient selection, implantation strategy, and preoperative and p

151 derpinnings that performs multi-class marker selection in an informed manner.

152 can be an alternative for performing feature selection in class-imbalanced data.

153 Selection in compartmentalized autocatalytic systems mig

154 l models however have not experienced strong selection in fonio, providing direct targets to rapidly

155 se CMR thresholds should be used for patient selection in future trials to determine if tricuspid val

156 tched Forest (MF), an algorithm for variable selection in matched case-control data.

157 ven and goal-directed influences compete for selection in memory, and that the balance of this compet

158 n domesticated animals is linked to positive selection in minor spliceosome components.

159 fer the opportunity for continued reciprocal selection in most populations.

160 ectodomain (rh-TfR1-ECD) followed by in vivo selection in mouse for brain parenchyma penetrating anti

161 ncer, the processes that underpin mutational selection in normal tissues remain poorly understood.

162 ting the importance of demographic-dependent selection in shaping functional phenotypic variation.

163 dN/dS) has become a popular method to detect selection in somatic cells.

164 ks in achieving robust performance for decoy selection in template-free protein structure prediction.

165 We now demonstrate that, following selection in the LZ, B cells migrated to specialized sit

166 riched for signatures of long-term balancing selection in the native ranges, with 15-47% of loci exhi

167 Genes under selection in tumors shows a high accuracy (92%) when eva

168 xity and discovering key biomarkers, feature selection is also an effective method of combating overl

169 Our results thus highlight that local selection is an important evolutionary force in natural

170 ctions with brain-wide activity drive action selection is less understood.

171 s well as autocatalytic kinetics; indeed, no selection is observed when all reacting species are diss

172 cally relevant TADs, has automatic parameter selection, is robust to sequencing depth, resolution, an

173 tagonistic pleiotropy and temporally varying selection maintain polymorphisms in natural populations;

174 onal studies that show that a conformational selection mechanism, in which POT1 binding is coupled to

175 ive site residues responsible for nucleoside selection, metal coordination, triphosphate binding, and

176 sssHD is a practical feature selection method for high-dimensional class-imbalanced d

177 probable stoichiometry, we introduce a model-selection method that is applicable for any multimeric c

178 However, most of the existing feature selection methodologies are biased towards considering o

179 Machine learning feature selection methods are needed to detect complex interacti

180 Despite being widely used, habitat selection models are rarely reliable and informative whe

181 ext of anthropogenic climate change and that selection now promotes thermal canalization and robustne

182 ap Tribrid mass spectrometer and begins with selection of a parent ion in the MS scan, followed by ta

183 isolate G15 airborne transmitted 100% after selection of a variant with a stabilized HA.

184 ries, the VTA->DH circuit can facilitate the selection of adaptive behaviors when current and past ex

185 patients at risk for cancer progression and selection of additional therapy.

186 tons from methylenecyclopropanes and a broad selection of alpha,beta-unsaturated aldehydes.

187 First, we show that the selection of alternative life histories depends on both

188 beginning in 2010 has significantly affected selection of anticoagulants for patients with VTE.

189 d in multiple individuals, indicating strong selection of B cell antigen receptors even in the absenc

190 s the error of inference by 30-35%, and that selection of cell-type informative probes has similar ef

191 igh-resolution mass spectrometry approach, a selection of chemical markers related to the geographica

192 A selection of commercial antibodies generated against SAR

193 Primary T(1)-initiated selection of components from the library assembles a par

194 Biomonitoring often requires a priori selection of compounds to be measured, and so, it may no

195 th surveillance, vaccine development and the selection of convalescent plasma donors.

196 A hypothesis for the evolutionary selection of ddl containing integron gene cassettes is p

197 sm of actions but also guides the design and selection of drug candidate molecules.

198 on procedure, suitable drug delivery system, selection of effective and safe dosage is the key to spa

199 ugh B cell receptor (BCR)-dependent positive selection of fetally derived precursors.

200 this is due to fixatives or tissue sampling, selection of gene panels for routine diagnosis should ta

201 features were recently proposed for precise selection of HCC patients for transplantation.

202 data give insights into the development and selection of humanized animal antibodies and provide act

203 deployment of novel TCR-T therapies, such as selection of ideal TCRs targeting validated epitopes wit

204 sculpts intratumor heterogeneity through the selection of immune-evasive clones.

205 Results are presented for the selection of insecticide-resistant vectors and the sprea

206 ndeavour, and provide a general guide to the selection of methods and molecular tools for probing int

207 plementation of azithromycin MDA may lead to selection of multiresistant pathogens.

208 For selection of novel functions the pools are typically tra

209 Such correlation allows for a priori selection of parameters for any desired compound without

210 tment, and results from recent trials in the selection of patients in an extended time window using p

211 We applied risk-set sampling for the selection of population controls (1:10), who were indivi

212 istance to unrelated classes may occur by co-selection of resistant strains, thus leading to the rapi

213 lcohol and 2-furoic acids were measured in a selection of roasted coffee products by isotope dilution

214 osomal instability may enable the continuous selection of SCNAs, which are established as ordered eve

215 oncogenic events may directly influence the selection of secondary concomitant alterations to promot

216 The selection of specific occupations can result in differen

217 se results support a novel mechanism for the selection of striatal circuit components, where fluctuat

218 rsistence, and memory formation by strategic selection of substrate cells, and gene-engineering with

219 However, careful selection of suitable patients is crucial.

220 and of 1.00:6.10:0.09 ha) to assist with the selection of suitable reintroduction sites for Southern

221 e immune mobilization depends on the correct selection of the microbial species used as the stimulant

222 Preferential selection of the mutant splice site likely reflects its

223 A common problem in this area is selection of the number of clusters (K).

224 and recipients (abdomen flukes) enables kin selection of the parasite's host-manipulating trait, whi

225 protein (snRNP) has an essential role in the selection of the precursor mRNA branch-site adenosine, t

226 severity and may help stratify patients and selection of therapeutic options.

227 r optimized detergent conditions can support selection of thermostable variants of experimentally dem

228 r contexts, this evolution may be due to the selection of these attributes for increased penetration.

229 e of exogenous cytokinins, which facilitates selection of transgenic plants without selectable marker

230 As a result, existing precursor selections often have significant gaps in reactivity or

231 plied to idfentify a wide range of events of selection (old and recent), and the haplotype-based stat

232 Group-level selection on culturally differentiated populations is on

233 d mass in sorghum was shaped by diversifying selection on drought stress, and can inform genomics-ena

234 hat social resistance can act as an agent of selection on key life-history strategies and promote the

235 a provide further evidence for heterogeneous selection on Mpi.

236 striking fashion [1, 2], indicating there is selection on parasite morphology to match the host (Bate

237 more variation in the sign and magnitude of selection on social behaviour than that experienced by s

238 ts under specific environments; as a result, selection on the timing of this transition could be a me

239 netic architecture and the effect of natural selection on these blood phenotypes between populations.

240 strate a transgenerational effect of extreme selection on toepad area for two populations struck by h

241 we know little about how natural and sexual selection operate on thermal reaction norms, reflecting

242 oupled with the least absolute shrinkage and selection operator (LASSO) algorithm were applied to pre

243 es and disadvantages, which makes viral tool selection paramount for properly designing and executing

244 heir habitats, and density-dependent habitat selection patterns may help to explain complex predator-

245 umbrellas including decision-making, action selection, perceptual categorization, and attentional se

246 r gene expression control in S. pneumoniae A selection platform is described that allows for straight

247 t their bindins show no evidence of positive selection, possibly because the two species spawn at dif

248 date sites are prioritized based on apparent selection pressure against mutations that disrupt miRNA

249 Our work shows how evolutionary selection pressure can cause proteins with local contact

250 esumably in response to strong environmental selection pressure.

251 high-ploidy tumors and thus support altered selection pressures upon WGD.

252 ity, validation of databases, patient cohort selection, procedure selection, duration of follow-up, s

253 ithm, and a comparison with several existing selection procedures is performed.

254 A systematic feature selection process was performed to select temporal and s

255 Therefore, during the salt selection process, the salt dissolution behavior should

256 ion error, ten methods of automated variable selection produced markedly different results; different

257 ionary outcomes and the effects of different selection regimes on TE dynamics in a specific genome ar

258 GW-TWAS method is based on Bayesian variable selection regression, which not only accounts for cis- a

259 Here, we investigate recent selection related to cognition in the paper wasp Poliste

260 Our screen for admixture-enabled selection relies on the identification of loci that cont

261 Appropriate drug selection remains crucial in this evolving landscape to

262 tic tumor profiling for targeted therapeutic selection remains limited to direct tissue acquisition.

263 constructs, and the application of in vitro selection, revealed that strong binding of OLE RNA by Oa

264 Landau levels (LLs) are described by simple selection rules associated with the LL index N.

265 Furthermore, the spin-valley optical selection rules(12-14) of transition metal dichalcogenid

266 elegans We developed a multiplexed negative selection screening approach in which edited loci are de

267 Here, we investigate how natural and sexual selection shape phenotypic plasticity in two congeneric

268 ld increase our understanding on how natural selection shapes the genetic composition of forest tree

269 We show that many spurious selection signals are eliminated by the use of unbiased

270 The highest level of variable selection stability over time was observed with LightGBM

271 Here, using an in vitro selection strategy, we determined the preferred DNA-bind

272 orrect when territoriality indicates habitat selection tactics that deviate from the IFD (e.g. ideal-

273 rials in both learning tasks, optimal target selection (task 1) and optimal reward structure selectio

274 ection (task 1) and optimal reward structure selection (task 2) required taking into account future p

275 al validation cohorts, and used five feature selection techniques to select 10 of 720 potentially pre

276 stringency and partially impairing negative selection, the host generates new virus-specific T cells

277 Selection to increase upper thermal tolerance was also p

278 ination of maximum length subtree and manual selection to maximize representation of Louisiana clones

279 patterns of plasticity shielded Daphnia from selection to permit long-term coexistence with a novel p

280 e fill this gap by incorporating the habitat selection traits at different flows of a freshwater apex

281 e protein isoforms is also considered in the selection tree, an aspect that is essential for a quanti

282 between modulating factors, as well as model selection uncertainty.

283 Selection under conditions that resolve highly active mu

284 pendent component analysis (ICA) and feature selection using DecompPipeline, (ii) deconvolution with

285 a coli and used as antigens in phage display selections using a synthetic human single-chain fragment

286 alience accelerates the speed of attentional selection, value-driven salience selectively enhances it

287 Model selection was guided by backward stepwise selection cond

288 transposition increase signatures by natural selection, we performed a laboratory evolution experimen

289 gistic regression and bootstrapped backwards selection were used to derive and internally validate ou

290 uidance for optimizing platform and software selection when designing an scRNA-seq study.

291 'drift' over time, and enhances homogeneous selection which is primarily imposed on Bacillales.

292 equires upfront algorithm and hyperparameter selection, which can introduce bias into the final clust

293 n, we reveal a bias in TCR recombination and selection, which is attributed to genomic position and t

294 st mechanisms for the evolution of substrate selection while maintaining common activation mechanisms

295 However, selection will likely take far longer (centuries) than c

296 and efficient approach for combining feature selection with classification.

297 election but little evidence of diversifying selection, with substitution rates comparable across str

298 Disentangling the drivers of natural selection within such communities is extremely challengi

299 T cells, a finding consistent with purifying selection within this lineage.

300 imers but deleterious in monomers; purifying selection would then prevent reversion to the unassemble