ライフサイエンスコーパス: selection pressure

1 esumably in response to strong environmental selection pressure.

2 h directly affect fitness and are subject to selection pressure.

3 pped the regions in Africa with the greatest selection pressure.

4 he subspecies japonica was under significant selection pressure.

5 ased substitution rates indicative of higher selection pressure.

6 nally important and thus subject to stronger selection pressure.

7 olving trait when populations face a chronic selection pressure.

8 rated [PSI (+)] strains in absence of strong selection pressure.

9 ard, enabling adaptive responding under this selection pressure.

10 nctionality of defence traits, and herbivore selection pressure.

11 e seeking treatment resulted in the greatest selection pressure.

12 ckcrossing followed by stabilization through selection pressure.

13 nagement should account for this predictable selection pressure.

14 es it to proliferate under strong antibiotic selection pressure.

15 in microbial fuel cell (MFC) under specific selection pressure.

16 netic variation that has experienced reduced selection pressure.

17 , revealing that ASP does impose significant selection pressure.

18 hat may have evolved in response to positive selection pressure.

19 at ac-Nglycs could be an alternative form of selection pressure.

20 henotype, due to phenotypic fluctuations and selection pressure.

21 s undergone a significant long-term shift in selection pressure.

22 miscuous activities presumed not to be under selection pressure.

23 ss likely to bypass them under drug-mediated selection pressure.

24 sms for sleep duration responding to natural selection pressure.

25 rental population were generated by removing selection pressure.

26 ts are consistent with persistent antibiotic selection pressure.

27 hrough conjugation, in the absence of direct selection pressure.

28 ent infection was driven by active intrahost selection pressure.

29 , quality, and diversity to specific natural selection pressures.

30 olve in multiple ways in response to similar selection pressures.

31 histories of feral populations, and by novel selection pressures.

32 nfection-associated, short-term, within-host selection pressures.

33 e two clubs potentially evolved via distinct selection pressures.

34 thine moths to respond to varying ecological selection pressures.

35 ry resilience of weed populations to extreme selection pressures.

36 splay sites often balance sexual and natural selection pressures.

37 stance genes in the absence of antimicrobial selection pressures.

38 a likely reflection of different underlying selection pressures.

39 r between opposing male- and female-specific selection pressures.

40 l trait, a memory "bottleneck" cannot escape selection pressures.

41 y result from a coevolution under particular selection pressures.

42 ular the available mechanisms and the likely selection pressures.

43 d to neurocognitive mechanisms and ancestral selection pressures.

44 ich these preferences change under different selection pressures.

45 ay exist among lineages exposed to identical selection pressures.

46 hips with humans and were subjected to novel selection pressures.

47 reflect constraints imposed by tumor fitness selection pressures.

48 pecific adaptations to cope with alternating selection pressures.

49 ly to reflect the effects of multiple sexual selection pressures.

50 or error-free repair of these uracils and by selection pressures.

51 hange via changes in both natural and sexual selection pressures.

52 ed to the selection of high content samples (selection pressure 20% and 30%) obtaining good sensitivi

53 ceptible, suggesting that factors other than selection pressure account for the clonal spread of drug

54 Selection pressure across entire CesA and Csl clades app

55 rocess and by the deterministic variation in selection pressures across environments.

56 s to a mosaic of spatially divergent disease selection pressures across their naturally fragmented di

57 also make raptors especially vulnerable when selection pressures act against these axes.

58 We then looked for evidence of selection pressure acting on asp Using computer simulati

59 counterparts, likely reflective of different selection pressures acting in wild and cultured populati

60 fluctuations more important than the average selection pressures acting on each new mutation.

61 stem captured salient features of real-world selection pressures acting on NA.

62 ry history is directly explained by distinct selection pressures acting on nocturnal, cathemeral, and

63 Selection pressures acting on the structure of non-codin

64 ndent events, leading to a decoupling of the selection pressures acting on these phenotypes.

65 egy to magnify the prevalence in response to selection pressures acting over hilly terrain.

66 s established tumors respond to chemotherapy selection pressure, additional genetic adaptations trans

67 date sites are prioritized based on apparent selection pressure against mutations that disrupt miRNA

68 ive variants with different allele frequency/selection pressure among (or between) ancestries without

69 bust to the presence of an additional strong selection pressure: an SBW25-specific virus.

70 In addition, selection pressure analyses showed that different select

71 or cell heterogeneity arising due to in vivo selection pressure and environmental influences and reca

72 ure, phylogenetic and motif characteristics, selection pressure and gene expression in plants.

73 nomic content network, finding that moderate selection pressure and high horizontal gene transfer rat

74 c loci can be driven by host adaptive immune selection pressure and may reveal proteins important for

75 ages, as well as provide information such as selection pressure and mutation analysis.

76 equilibrium via recursive cycling imposes a selection pressure and subsequent boundary conditions on

77 is study, we show that the RRE is subject to selection pressure and that RREs from later time points

78 egrated HIV DNA has the potential to obscure selection pressures and confound the interpretation of c

79 hese new factors, which introduce additional selection pressures and constraints, significantly influ

80 ow concentrations of insecticide, and allows selection pressures and dominance values to differ depen

81 tion rates, which permit rapid adaptation to selection pressures and have other important biological

82 which closely related species share similar selection pressures and limited dispersal from ancestral

83 abitat phenology is critical for identifying selection pressures and tradeoffs at different life hist

84 that are dynamically shaped by environmental selection pressures and transcend multiple trophic level

85 that rotation treatments intuitively reduce selection pressure, and are effective when insecticides

86 measuring repertoire diversity, quantifying selection pressure, and calculating sequence chemical pr

87 amples of adaptive introgression, grouped by selection pressure, and consider the level of supporting

88 ic RNA binding proteins (RBPs), evolutionary selection pressure, and coupling of AS with nonsense-med

89 n; founder effects are more significant than selection pressure; and the clustering threshold for sub

90 d variants resulted from antiretroviral drug selection pressure, APOBEC-mediated editing, and natural

91 es in resistant populations when there is no selection pressure applied.

92 Antagonistic natural selection pressures are likely involved in shaping the o

93 these findings to natural populations, where selection pressures are unknown.

94 tidrug resistance might depend on antibiotic selection pressures arising from population use of speci

95 sal and associated exchanges, with purifying selection pressure as the principal evolutionary force.

96 fitness constraints and identify non-obvious selection pressures as emergent features.

97 d evolutionary event may reflect a change in selection pressures as rabbit numbers declined following

98 driven by the immune response, and purifying selection pressure asserted by deleterious mutations.

99 lar evolutionary analyses revealed shifts in selection pressure at both the gene and the codon level

100 ivating PDGFRA mutations that display strong selection pressure at recurrence.

101 train-specific nAbs and bNAbs indicated that selection pressure at these residues increased with the

102 Analysis of lentiviral evolutionary selection pressures at the individual versus population

103 r predicted TF-related env mutations using a selection pressure-based approach, followed by an analys

104 e two fitness metrics and their estimates of selection pressures, before and during a demographic tra

105 Host defense may have been the original selection pressure behind the development of mechanisms

106 showed differences in genomic diversity and selection pressure between these three sub-groups.

107 mutations are expected to be under negative selection pressure, but the extent of the resulting neoa

108 cumented to threaten wild plants with strong selection pressures, but how plant populations respond g

109 tion is generally consistent with ecological selection pressures, but that ecological characters are

110 on under different circumstances, create new selection pressures by changing ecology or behaviour, an

111 Our work shows how evolutionary selection pressure can cause proteins with local contact

112 The timing of selection pressure characterized individual epitope spec

113 Evolutionary rates and selection pressure coevolve with macrostructural and mic

114 The evident shift in selection pressures correlates to the regional European-

115 ion: they do not present us with group-level selection pressures counteracting individual-level ones,

116 The strong, opposing selection pressures, coupled with documented highly vari

117 persist in indigenous populations when under selection pressure, disappearing when this carbon source

118 ion, latent reservoir dynamics, diversifying selection pressure driven by the immune response, and pu

119 Yet, selection pressures driving DENV microevolution within h

120 Starvation is among the most ancient of selection pressures, driving evolution of a robust arsen

121 system of Escherichia coli under a designed selection pressure during adaptive laboratory evolution.

122 nism, L. vannamei has been subjected to high selection pressure during the past 30 years of breeding,

123 control measures, removal of key antibiotic selection pressures during a national antibiotic steward

124 roughness can be different, depending on the selection pressures during evolution.

125 Our results support that different selection pressures (e.g. environmental constraints, hum

126 pacity of organisms to adapt to the multiple selection pressures encountered in natural environments.

127 y gain a survival advantage where antibiotic selection pressures exceed critical thresholds.

128 The intense selection pressure exerted by bed nets has precipitated

129 The selection pressure exerted by herbicides has led to the

130 Selection pressure exerted by the host insect as a resul

131 We also found that the selection pressures exerted by different fitness landsca

132 ) and (2) there are similarities between the selection pressures exerted by domestication and by urba

133 in vascularized tissue, we investigated the selection pressures exerted by spatial and temporal vari

134 Selection pressures exerted on Staphylococcus aureus by

135 des of HSV-2 infection and imply that strong selection pressures exist to maintain the fidelity of th

136 Our findings suggest that selection pressure exists for early mating readiness and

137 uman strains since 1918, which suggests that selection pressure exists on this domain.

138 between cells in a group, and determined the selection pressures experienced by these cells.

139 r dispersed duplication differ in abundance, selection pressure, expression divergence, and gene conv

140 Competition for substrates is a ubiquitous selection pressure faced by microbes, yet intracellular

141 vironment for virus transmission changed the selection pressures faced by MYXV, altering the course a

142 ids but reappearing in several lineages when selection pressures favored its evolution.

143 This modular assembly implies a selection pressure favoring substrate channeling.

144 These results indicate that selection pressure for enhanced viral fitness may drive

145 Despite no obvious selection pressure for LD-crosslinking or lysozyme resis

146 ous substitution rates showed a more relaxed selection pressure for non-syntenic genes compared to sy

147 exposure conditions may require independent selection pressure for survival to each variant in order

148 tudies have identified herbivory as a likely selection pressure for the evolution of hyperaccumulatio

149 s over the last 10 Ma may have operated as a selection pressure for traits and behaviors in Homo such

150 -scale shift to oral vancomycin may increase selection pressure for vancomycin-resistant Enterococci

151 They also indicate that selection pressures for animals to transmit important in

152 results suggest that there have been strong selection pressures for G. australis to maintain broad s

153 minimization but instead reflect competitive selection pressures for integrated network topology as a

154 ugh these adaptations are assumed to reflect selection pressures for males to lower frequency compone

155 t species with low syntopy should have lower selection pressures for more constitutive (always presen

156 infer eco-evolutionary dynamics and in vivo selection pressures for strains within individuals.

157 e and prognostic relevance, the evolutionary selection pressures for WGD in cancer have not been inve

158 remained relatively stable despite prolonged selection pressure from antibiotics.

159 quency of resistance genes in the absence of selection pressure from antimicrobials.

160 enomic aspects of population bottlenecks and selection pressure from geographical isolation, host ran

161 eases in mean seed production have increased selection pressure from seed predators but not from poll

162 This may result from the variety of selection pressures from herbivores, long distance gene

163 ruses of humans evolve rapidly due to strong selection pressures from host immune responses, principa

164 evolution by control agents, and contrasting selection pressures from other enemy species).

165 Similarly, removal of selection pressure generally leads to decay in resistanc

166 Despite these selection pressures, genetic covariation of morphology,

167 We show that relaxed selection pressure has allowed expression of FLC paralog

168 loop could arise in the field due to immune selection pressure; however, due to reduced HA stability

169 in some clinical settings to properly study selection pressures.IMPORTANCE The major implication of

170 ds were ineffective in disentangling the two selection pressures imposed by both the Env and ASP prot

171 ivating RTK variants that are enriched under selection pressure in a model of cancer heterogeneity an

172 the immune microenvironment exerts a strong selection pressure in early-stage, untreated non-small-c

173 ass I-restricted epitopes under reproducible selection pressure in HBV core; the possibility of viral

174 associated rare variants are under different selection pressure in Japanese and European populations.

175 inants were identified among mutations under selection pressure in non-candidate genes.

176 e on dietary choline would be under negative selection pressure in settings where choline intake is l

177 by life-long combinatorial antibiotic (ABX) selection pressure in the APPSWE/PS1DeltaE9 mouse model

178 ium induces survival pathways and provides a selection pressure in the continuum of ERG dependent neo

179 either emerges in response to an antifungal selection pressure in the individual patient or, more ra

180 less fit in mountain lions and under intense selection pressure in the novel host.

181 e identified nine residues in HBV core under selection pressure in the presence of 10 different HLA c

182 Residues under selection pressure in the presence of particular HLA cla

183 exhibited no evidence for positive Ag-driven selection pressure in their CDRs in contrast to non-pSS

184 antibody-mediated neutralization driving the selection pressure in viral evasion.

185 most likely when perceptual biases are under selection pressures in other contexts (e.g., detection o

186 itive abilities has been among the strongest selection pressures in P. fuscatus' recent evolutionary

187 The selection pressures in this environment have spurred the

188 regions using the selection rate and detect selection pressures in viral proteins and in the immune

189 NA genome has evolved in response to complex selection pressures, including the need to maintain stru

190 nfections can provide insights into how host selection pressures-including immune responses and thera

191 tant bacteria (ARB) is fuelled by antibiotic selection pressure, inter-organism transmission of resis

192 their adaptation to environmental and human selection pressure is at the root of their remarkable di

193 developing mammary carcinomas, and that such selection pressure is higher in the presence of ErbB2 ac

194 reaction is enzymatically driven, and that a selection pressure is operating to retain type II NAD(P)

195 Studying how viruses respond to selection pressures is important for understanding mecha

196 that is subject to strong microenvironmental selection pressures later in tumor evolution.

197 t 70 years has imposed strong and widespread selection pressure, leading to the evolution of herbicid

198 Selection pressure led to the loss of two ribosomal prot

199 Resulting selection pressures led to changes in diet and dietary a

200 ns' social networks might partly result from selection pressures linked to our extensive reliance on

201 What selection pressures maintain the morphs in multiple daug

202 In contrast, the selection pressures (measured as ratios of nonsynonymous

203 interactions occurs through the interplay of selection pressures moving along multiple direct and ind

204 These results suggest disparate selection pressures occur with age upon B-1a cells expre

205 These results point toward a differential selection pressure of N-glycosylation site acquisition d

206 Our study demonstrates that the selection pressures of a 3(rd) generation cephalosporin

207 ilemma as one DNA sequence evolves under the selection pressures of multiple proteins.

208 se of antimicrobials, potentially increasing selection pressure on bacteria to become resistant.

209 of cold-responsive genes as well as between selection pressure on coding sequences of genes and thei

210 ese data indicate that infant CTLs can exert selection pressure on gag and nef epitopes in early infe

211 use novel environmental conditions alter the selection pressure on genes or entire subgenomes, adapti

212 nodominance over Gag and strong Env-mediated selection pressure on HIV are observed only in subjects

213 e consequences of serial passage with strong selection pressure on its fitness.

214 Furthermore, we identified an asymmetric selection pressure on Magnaporthe species.

215 al toxicants such as pesticides exert strong selection pressure on many species.

216 rol the disease have intensified, so has the selection pressure on mosquitoes to develop resistance t

217 g evolution N-glycosylation triggered a dual selection pressure on secretory pathway proteins: while

218 ed to study linkages between TDR strains and selection pressure on TDR-associated DRMs.

219 cies, chemical mate guarding may also impose selection pressure on the long-range female sex pheromon

220 v Forrest, although required, does not exert selection pressure on the nematode to shift from HG type

221 revealed that mice continuously exerted CTL selection pressure on the persisting virus population.

222 Results are consistent with selection pressure on the viral genome imposed by local

223 nal avidity (P < 0.0001) and drives stronger selection pressure on the virus than HLA-B*14-DA9.

224 stigate how a series of disturbances applied selection pressure on these FBTs, causing the disproport

225 ient glycan degrading systems exerts a major selection pressure on this microbial community.

226 ient glycan degrading systems exerts a major selection pressure on this microbial community.

227 vesting, which in animals can exert a strong selection pressure on various traits, sometimes greater

228 xplore the implications of these compounding selection pressures on food-seeking motivation during br

229 ory of combat exerted powerful and sustained selection pressures on male groups, individual identific

230 c eukaryotic microbes may experience similar selection pressures on mutation rate as bacterial pathog

231 Invasive plants impose novel selection pressures on naive mutualistic interactions be

232 us in tropical forests, could strongly alter selection pressures on plants, resulting in widespread,

233 acid variants indicated strong host-specific selection pressures on proteins involved in viral moveme

234 ework for understanding the origin of global selection pressures on proteins.

235 hat provide mechanistic insights, detail the selection pressures on proteome allocation and address s

236 data indicate that (i) there may be distinct selection pressures on SARS-CoV-2 replication or infecti

237 in vitro; thus, there appears to be distinct selection pressures on SARS-CoV-2 sequences in vitro and

238 Here, we investigate the selection pressures on sequence variants that predispose

239 Here, we investigate whether conflicting selection pressures on siderophore production by heavy m

240 Atlantic salmon (Salmo salar) parents alter selection pressures on their offspring with important co

241 ntegrated from unintegrated DNA, even though selection pressures on these two forms should be distinc

242 The selection pressures operating on combinations of HLA all

243 rains studied here, reflecting the different selection pressures operating on them.

244 e either recruited to processes under strong selection pressure or to processes supporting an evolvin

245 each site for each amino acid given a single selection pressure, or assess the extent to which these

246 ution shifts across trajectories to quantify selection pressure, population expansion, and developmen

247 erved effects of parent-derived nutrients on selection pressures provide experimental evidence for ke

248 lutionary implications of temporally varying selection pressures remain poorly understood.

249 terns in timing and persistence of antiviral selection pressure, remain, however, incompletely define

250 Predicting how species will respond to selection pressures requires understanding the factors t

251 l proteins, although the specific traits and selection pressures responsible for the maintenance of d

252 Our results reflect that selection pressure resulting from global cooling must ha

253 Our findings suggest selection pressures resulting from the different manure

254 ulting redundancy of RITS may have eased the selection pressure, resulting in progressive loss or tru

255 , consistent with the theory that antibiotic selection pressure results in clonal expansion of existi

256 Selection pressures shaping the IgG and IgA repertoire w

257 nabling adaptive responding under this basic selection pressure.SIGNIFICANCE STATEMENT Among the most

258 y parallel phenotypes in response to similar selection pressures suggesting that there may be shared

259 wer children and are under stronger negative selection pressure than common sequence variants.

260 er the course of infection, with evidence of selection pressure that led to sequence convergence as d

261 A. coluzzii/A. gambiae hybrids, and provided selection pressure that swept the 2L divergence island t

262 ates adaptation in response to the immediate selection pressures that a virus experiences in its curr

263 Since the selection pressures that act upon cultured and natural p

264 on of a tumor ecosystem depends on different selection pressures that are principally immune and trea

265 actions is evidenced by the intense adaptive selection pressures that dominate the evolutionary histo

266 t mutant clones in a quiescent state, strong selection pressures that kill the wild type promote drug

267 atomy of the early vertebrate retina and the selection pressures that may have led to the evolution o

268 e to diverse, ultimately ineffective, immune selection pressures that randomly change from host to ho

269 In seeking to understand the selection pressures that shaped the plant calcium-signal

270 an environment where there is no continuous selection pressure the network connectivity, described b

271 med that HPV-positive cancer cells are under selection pressure to continuously express the viral E6/

272 t strategies are likely to impose additional selection pressure to drive acquisition of mutations in

273 aptive immune system, may have evolved under selection pressure to encode a binding motif innately ca

274 P do not display this tendency, suggesting a selection pressure to fine tune allostery on changes to

275 eptococcal species and, as such, is under no selection pressure to maintain binding affinity and/or c

276 the shortest chromosomes, and is subject to selection pressure to maintain the hyperrecombinogenic p

277 ) inhibits brain activity and has acted as a selection pressure to reduce GABAergic tone, which in tu

278 tants to both drug and inducer should create selection pressure to regain drug resistance and possibl

279 In general, we hypothesize an evolutionary selection pressure to retain slow relaxation dynamics-in

280 We sought mutations under similar selection pressure to those characterised as resistance

281 How selection pressures to escape immune recognition, mainta

282 ance of considering multiple and conflicting selection pressures to explain rewards.

283 e uncertainties pose a challenge when tuning selection pressures to isolate high-affinity ligands.

284 l proteome of organisms through evolutionary selection pressures to modulate protein synthesis speed

285 extensive clinical intervention and intense selection pressure toward a pathogen lifestyle that invo

286 ce populations is critical for understanding selection pressures underlying strategies that minimize

287 high-ploidy tumors and thus support altered selection pressures upon WGD.

288 including nucleotide substitution rates and selection pressures, using 14 IAV subtypes in 32 differe

289 term effects of a famine and the reversal of selection pressure via the survival component of annual

290 ions were detected showing that the dominant selection pressure was antibiotic treatment.

291 process analysis showing that environmental selection pressure was higher in burned sites.

292 Evidence for selection pressure was recognized for several amino acid

293 Selection pressure was stronger in infants with non-seve

294 By using drug-selection pressure, we generated VSG double-expresser T.

295 d other crops, no significant differences in selection pressure were detected between the subgenomes

296 tated Ig sequences in vivo in the absence of selection pressures, which skew the observed mutation pa

297 onary) and strong positive (antigenic drift) selection pressures, which were coincident with advancin

298 curacy should be expected over error because selection pressures will have shaped social perception t

299 us an example of an acute infection in which selection pressures within infected individuals drive ra

300 In this study, we investigate host-specific selection pressures, within-host viral fitness, and inte