ライフサイエンスコーパス: selective force

1 onstraint on host condition and an important selective force.

2 with environmental factors often invoked as selective forces.

3 ammals and may be due to both mutational and selective forces.

4 ocess driven by definable microenvironmental selective forces.

5 ing these processes are subject to divergent selective forces.

6 tentially as a result of individual-specific selective forces.

7 n similar ways by virtue of similarly acting selective forces.

8 petition is therefore influenced by multiple selective forces.

9 es population that can evolve in response to selective forces.

10 s rise to speculation concerning the role of selective forces.

11 enetic mechanisms drive adaptation to common selective forces.

12 olution, presumably owing to male-beneficial selective forces.

13 rivers of biogeochemical cycles and powerful selective forces.

14 life strategies and are shaped by different selective forces.

15 e maintained in a population by a balance of selective forces.

16 although purifying selection is the dominant selective force acting on the mitochondrial genome in Ta

17 ation is the viral pol gene and the dominant selective force acting on this feline immunodeficiency v

18 opulations, therefore, are shaped largely by selective forces acting at the genomic level between ele

19 ept under special circumstances, conflicting selective forces acting on a pleiotropic gene might main

20 Nevertheless, the selective forces acting on competition and the resulting

21 In addition, we found signatures of ancient selective forces acting on different African TAS2R38 hap

22 is the inevitable consequence of conflictive selective forces acting on differentially expressed pare

23 the determinants of trait variation and the selective forces acting on it in natural populations wou

24 stions concerning functional equivalency and selective forces acting on its multiple alleles.

25 l regulator, Notch1, may explain some of the selective forces acting on MAGP2.

26 To evaluate the selective forces acting on nonsense SNPs as a class, we

27 e X and Y chromosomes are thought to reflect selective forces acting on original pairs of identical c

28 overies open new opportunities to understand selective forces acting on phenotypic traits.

29 ing ploidy cycles to balance the conflicting selective forces acting on rapidly growing phagotrophic

30 To evaluate rigorously the effects of selective forces acting on retrotransposons, detailed in

31 provide evidence for a relaxation of recent selective forces acting on this gene and a revised hypot

32 roughout the genome, and only secondarily by selective forces acting on translated sequences.

33 quenced bacterial genomes confirmed that the selective forces acting on translation vary with the eco

34 " coincided with a major global shift in the selective forces acting on various SARS-CoV-2 genes.

35 basis of the heritability of traits and the selective forces acting upon them.

36 ts surviving malaria is the most significant selective force affecting the expression of blood groups

37 This is suggestive of similar selective forces affecting the diverse SMBDs and resulti

38 ole in the life cycle could balance opposing selective forces allowing the stable maintenance of both

39 es of parental origin effects under a single selective force and identifies a single substrate throug

40 ess illustrates the dynamics of antagonistic selective forces and allows the systematic derivation of

41 Our findings provide insights into the selective forces and ecological factors that may have dr

42 Because this empirical framework identifies selective forces and genetic architectures responsible f

43 new perspective about the complexity of the selective forces and mechanisms that shape the generatio

44 on does not easily translate into a positive selective force, and the nature of that selective force,

45 evolution of spermatogenesis and associated selective forces, and provides a resource for investigat

46 ctively determine the mechanistic origin(s), selective forces, and trajectories of transient or persi

47 ional and sometimes maybe even contradictory selective forces appear to affect codon usage as well.

48 ancestral allele), suggesting that different selective forces are acting.

49 The end result of these selective forces are parental origin effects, writ large

50 We presume that random events rather than selective forces are responsible for the observed high s

51 Together, these results suggest complex selective forces-arising from differential peptide bindi

52 ng their evolution to similar mutational and selective forces as IncPalpha plasmids and may have evol

53 tuitive expectation that the relatively weak selective force associated with metabolic efficiency wou

54 tentially informative about the magnitude of selective forces associated with amino acid replacements

55 t mitosis or female meiosis, are the primary selective force behind centromere-drive suppression.

56 nsights into the genetic basis and potential selective forces behind phenotypic variation in what is

57 However, selective forces both inside and outside of human hosts

58 Our findings predict that this ongoing selective force by the mosquito immune system could infl

59 t components of a mating signal suggest that selective forces can act in concert on multiple aspects

60 at the dynamics of entropic forces balancing selective forces can be used to predict how long it will

61 Even weak selective forces can bias transmission of one genome ove

62 What selective forces contribute to eye loss in cave animals?

63 res and the corresponding concepts of stress-selective force-coupled reactivity and strand continuity

64 This behaviour arises from stress-selective force-coupled TCB reactivity when stress is im

65 to their local conditions, but the specific selective forces creating this adaptation are often uncl

66 that in the post-reproductive stage of life, selective forces decline allowing many vital systems to

67 --female interactions, a prerequisite if the selective forces derive from sexual conflicts.

68 ructs; the outcomes are subject to competing selective forces deriving from the fitness properties of

69 Different selective forces determine survival in the planktonic an

70 robial interactions have been suggested as a selective force, direct binding of lethal pathogens to A

71 However, it remains unclear as to what selective forces drive the evolution and existence of tr

72 esults in which nonsense errors are the only selective force driving CUB evolution.

73 cate phosphorus availability as the dominant selective force driving divergence between these populat

74 olution in plants provides insights into the selective forces driving adaptation and the genetic basi

75 umulation in each lineage indicates that the selective forces driving adaptive evolution in gene expr

76 ply that mate and/or gamete choice are major selective forces driving genetic change in sexual popula

77 The selective forces driving pseudogenization within gene fa

78 rk of HIV-1 infection, and understanding the selective forces driving the emergence of viral variants

79 ragnathidae) and aiming at understanding the selective forces driving the female in the choice of the

80 The selective forces driving these patterns may include the

81 mphasize the importance of understanding the selective forces driving viral adaptation to a new host.

82 nbiased systems approaches to study the host-selective forces driving VOC evolution.

83 riants, but also they demonstrate that other selective forces exist during acute infection.

84 unique demographic history, even as similar selective forces facilitate their resilience to malaria

85 genome content may not be fixed, as changing selective forces favor particular phenotypes; however, o

86 survival and behaviour and may be exerting a selective force for certain species and traits.

87 te that human APOBEC3H is not as strong of a selective force for current HIV-1 infections as human AP

88 rldwide, making AIDS, like malaria, a strong selective force for disease-associated genetic factors.

89 rationale is its role in senescence, but the selective force for inactivation of p18(INK4c) in incipi

90 response adaptations represent an important selective force for influencing diversity within marine

91 d that early-life adversity (ELA) is a major selective force for many taxa, in part via its ties to a

92 e idea that a redox-sensitive mechanism is a selective force for recruiting lens crystallins.

93 the majority of the Cd, thereby removing the selective force for resistance.

94 The results showed that the selective force for the dissimilarity of the pioneer bac

95 specific sensory organs may be an important selective force for the evolution of elaborate and multi

96 fector targets may have provided the driving selective force for the evolution of guard proteins.

97 ntagonistic (SA) polymorphisms] are the main selective force for the evolution of recombination suppr

98 ed that external immunity acts as a powerful selective force for virulence evolution, with an increas

99 ariation, we suggest that both mutagenic and selective forces generate these correlations, the latter

100 eriments with their phylogeny to reconstruct selective forces generating serpentine soil endemism, wh

101 erstanding of evolution processes, where the selective forces giving rise to new, not clearly adaptiv

102 analyzing rare mutations, understanding the selective forces guiding affinity maturation, and unders

103 n a comparative manner and show that similar selective forces have shaped the unique evolution of sex

104 nd report experimental evidence for powerful selective forces impelling the evolution of both eusocia

105 Finally, the selective forces imposed on these dual coding regions wi

106 in feeding flux do not seem to be a dominant selective force in cell design.

107 n ancient retroviral pandemic as a prominent selective force in chimpanzee evolution, adaptation of c

108 ific conflict can be an especially important selective force in high-density invasive populations, wh

109 CTL selection, confirming CTLs as a dominant selective force in HIV-1 infection.

110 t immune control over HIV and so are a major selective force in its evolution.

111 rtant component of human relationships and a selective force in our species history beginning at leas

112 which would have also been an important and selective force in our species' history.

113 his disease being the strongest evolutionary selective force in recent human history, and genes that

114 social behavior has been a strikingly potent selective force in shaping brains to control action.

115 ngth (and possibly the universality) of this selective force in shaping S. cerevisiae's proteome.

116 primates, and are argued to be an important selective force in social evolution.

117 interactions is predicted to be an important selective force in the diversification of communication

118 iability has long been postulated as a major selective force in the evolution of large brains.

119 Nutrient availability is a major selective force in the evolution of metazoa, and thus pl

120 The dominant selective force in the evolution of recombination and se

121 biotic feeding in food animals has been as a selective force in the evolution of their intestinal bac

122 myovirus P-SSM2 under P limitation, a strong selective force in the oceans.

123 that dedifferentiation acts like a positive selective force in the stem cell population and thus spe

124 al closely related congeners and is likely a selective force in the sub-social route to permanent soc

125 functional genomes, acting as a significant selective force in viral evolution.

126 r discussion of the roles of mechanistic and selective forces in determining the distribution of gene

127 speaks to the persistence and potency of the selective forces in marine environments that challenge f

128 the Olfr gene family has encountered unusual selective forces in neural cells that have driven them t

129 erochromatization, reflects the diversity of selective forces in operation.

130 Water stress is one of the primary selective forces in plant evolution.

131 he landscape of both persistent and episodic selective forces in this species.

132 We find that selective forces in tumoural regions furthest from the b

133 To examine these selective forces in vitro, we genetically engineered P.

134 tive selective force, and the nature of that selective force, in the past and/or currently, remains s

135 ional response to a broad range of potential selective forces, including colony growth, competition,

136 thaliana may have been maintained by complex selective forces, including those from the fitness benef

137 te a pervasive mutational bias toward A+T, a selective force, independent of adaptive codon use, is d

138 o predict the ability of the virus to escape selective forces induced by host immune responses as wel

139 ts ecological niche differentiation, but the selective forces influencing this are not well defined.

140 estimates in Drosophila of the intensity of selective forces involved seem too large to be reconcile

141 that both effects are in response to similar selective forces involving the innate immune system.

142 ntrols, but the relative importance of these selective forces is unknown.

143 owth in vertebrates and a focal point of the selective forces leading to genomic imprinting.

144 h mesendodermal expression hypothesised as a selective force maintaining cluster integrity.

145 n in yeast, we obtained evidence of a potent selective force, manifesting as a spontaneous doubling i

146 Naturally selective forces may create countering selection pressur

147 wo mating strategies are subject to opposing selective forces, mixed breeding systems are thought to

148 by S. mutans, termed mutacins, may provide a selective force necessary for initial or sustained colon

149 es are common strategies for coping with the selective force of predation in heterogeneous environmen

150 Because Nef is highly polymorphic due to the selective forces of host cellular immunity, we hypothesi

151 ckroaches seem to be shaped primarily by the selective forces of microhabitat and functional niche, t

152 study, we test whether fire imposes a broad selective force on a key fire-tolerance trait, bark thic

153 iation can amplify or dilute parasitism as a selective force on hosts and parasites, driving populati

154 that habitat bareness is an underappreciated selective force on plants in harsh environments.

155 Plasmodium falciparum has acted as a potent selective force on the human genome.

156 Malaria has been a major selective force on the human population, and several ery

157 enous extracellular matrix) exert a dramatic selective force on the tumor, which grows as an invasive

158 intestinal helminths represent an important selective force on their mammalian host.

159 The environment imposes critical selective forces on all living organisms, and the sessil

160 opulations has been shaped by the balance of selective forces on IL4's diverse roles.

161 ry to quantify the interplay of entropic and selective forces on nucleotide organization and apply it

162 determine whether natural enemies can act as selective forces on plant defense.

163 nding soil, at the rhizosphere, plants exert selective forces on their bacterial colonizers.

164 re this phylogenetic distinction indicates a selective force operating between the two habitats.

165 /het-S allele ratios by the existence of two selective forces operating at different levels.

166 s the feasibility and utility of gauging the selective forces operating on bacterial IGRs from whole-

167 polymorphisms, thereby providing clues about selective forces operative in the host.

168 tion expansion and divergence indicates that selective forces or specific chromosomal mechanisms resu

169 disruptions are quickly erased by quotidian selective forces, or whether they have the potential to

170 s life and has been a powerful and essential selective force over evolution.

171 material was also observed, suggesting that selective forces play a role in syntax development as we

172 levance as they can provide insight into the selective forces potentially driving deviations from sta

173 ity patterns in primates are shaped by local selective forces rather than phylogenetic history.

174 attempt to explain the nature of the unknown selective force responsible for the robust positive sele

175 However, the selective forces responsible for the emergence of geneti

176 t on the relative contributions of different selective forces responsible for the observed patterns.

177 However, our understanding of the selective forces responsible in a given case, and the ro

178 s costs of resistance in the human host, and selective forces resulting from interventions such as an

179 ancestor, it may be possible to identify the selective force(s).

180 id ecological change, one of the most potent selective forces, sexual selection, remains curiously un

181 The extent to which selective forces shape patterns of genetic and genealogi

182 surrounding geochemical regimes is a strong selective force shaping microbial communities throughout

183 Metabolic efficiency, as a selective force shaping proteomes, has been shown to exi

184 ed the prevalence, genomic determinants, and selective forces shaping cis-regulatory variation in the

185 marked migratory change, but quantifying the selective forces shaping evolutionary changes remains ch

186 When considering selective forces shaping human evolution, the importance

187 its is important in our understanding of the selective forces shaping life history evolution.

188 To uncover the selective forces shaping life-history trait evolution ac

189 lar environment may provide insight into the selective forces shaping microbial communities.

190 Our findings provide insight into selective forces shaping plastic and genetic variation.

191 Our results indicate that the selective forces shaping the size and organization of th

192 ivory when prey quality is low, and reveal a selective force (sterol nutrition) that drives predatory

193 ected people when viral load is high or when selective forces strongly drive mutation.

194 tation rates allow HIV-1 to adapt rapidly to selective forces such as antiretroviral therapy and immu

195 tly virulence expression requires additional selective forces such as narrow population bottlenecks d

196 life, both commercial and recreational, is a selective force that can induce evolutionary changes to

197 ability to degrade propanediol provides the selective force that maintains B12 synthesis in this gro

198 Our findings show that cell competition is a selective force that optimizes vertebrate tissue functio

199 st-impact perturbations could have exerted a selective force that was exacerbated by seasonal timing.

200 ty, identify new architectures, and quantify selective forces that act on specific NLRs and NLR domai

201 However, the selective forces that affect genetic adaptations and how

202 Yet, mating systems can introduce selective forces that alter these expectations; with div

203 e same pathways and proteins, as well as the selective forces that are acting on these mutations and

204 merges and then diversifies over time due to selective forces that are poorly understood.

205 ting biotic pressures generate heterogeneous selective forces that can maintain standing natural vari

206 This implies the operation of selective forces that confer an advantage to sexuality a

207 n primates and carnivorans in the balance of selective forces that constrain larynx size and highligh

208 Here, we provide a detailed analysis of the selective forces that determine the emergence and stabil

209 Identifying the primary selective forces that drive migration ultimately require

210 The selective forces that drive the emergence of new infecti

211 mation is desirable to better understand the selective forces that drive the evolution of QS phenotyp

212 during the acute phase of infection, but the selective forces that drive this process remain poorly d

213 ence mating behaviour, and in particular the selective forces that explain the evolution of female pr

214 We aimed to compare the selective forces that forge the IgG4 and IgE repertoires

215 ing conflict may thus be responsible for the selective forces that generate parent-offspring coadapta

216 The selective forces that govern gliomagenesis are strong, s

217 ness molecular data to draw inferences about selective forces that have acted on genomes.

218 ate goal of testing hypotheses regarding the selective forces that have led to changes in such an ess

219 We then discuss the selective forces that have likely shaped interference an

220 ouse and human genomes has shed light on the selective forces that have predominated in their recent

221 the genetic and environmental conditions and selective forces that have shaped evolution of this comp

222 iversity, we determined the past and present selective forces that have shaped the current variabilit

223 xists, then it is tempting to argue that the selective forces that have shaped the evolution of forag

224 recent global spread, and to understand the selective forces that have shaped the unique aspects of

225 dditive HGT, the proposed mechanisms of HGT, selective forces that influence HGT, and the evolutionar

226 n of mammalian orthologs to determine if the selective forces that led to the degeneration of the Y c

227 We examine the selective forces that likely drove the evolution of high

228 However, our understanding of the selective forces that maintain prophages in bacterial po

229 ate of Y chromosome evolution and assess the selective forces that may act upon such genes, and provi

230 and presumably other host genes, affects the selective forces that operate on virus populations in vi

231 from Oryza sativa to investigate the type of selective forces that potentially limit their amplificat

232 ishing neutral nonequilibrium processes from selective forces that produce similar patterns of variat

233 This approach provides a framework of the selective forces that shape functional variation within

234 sights into the historical, demographic, and selective forces that shape speciation.

235 Identification of the selective forces that shaped adaptive phenotypes general

236 real time and the mutational mechanisms and selective forces that shaped the evolution of SARS-CoV-2

237 eceptor switch is not well explained by host selective forces that should be relatively constant betw

238 all- and large-scale mutations, but also the selective forces that they encounter once they arise.

239 bably been subjected to similar evolutionary selective forces, their B-cell responses would be analog

240 e Batesian mimic, demonstrating the powerful selective force these predators exert on mimetic resembl

241 bility that flagellin receptors provided the selective force to drive the evolution of these unique s

242 s, but how the immune infiltration acts as a selective force to shape the clonal evolution of ESCC is

243 ains rare for both the genetic basis and the selective forces to be known, leading to an incomplete u

244 ontribution of developmental constraints and selective forces to the determination of evolutionary pa

245 Under these selective forces, together known as balancing selection,

246 ure research on the genetic architecture and selective forces underlying cryptic coloration traits.

247 that reproductively isolate species, and the selective forces underlying their divergence, is a centr

248 retical work has clarified the processes and selective forces underlying this effect and has demonstr

249 As seismic activity is a non-selective force we recovered specimen of algae and Insec

250 addition, our findings showed that when both selective forces were applied, it led to a higher commun

251 se the host is the principal environment and selective force, whereas for hosts, parasite-mediated se

252 Spatial expansion thus creates a selective force whereby cooperator-enriched demes overta

253 altering their dinucleotide motif use under selective forces, with these forces on CpG dinucleotides

254 adaptations to this stress could represent a selective force within, and between, 'species', also kno

255 n undergo massive gene losses, for which the selective forces within host tissues are unknown.