ライフサイエンスコーパス: self-recognition

1 ith (S)-5(+) than with (R)-5(+) ("enantiomer self-recognition").

2 fit is weighed against the cost of potential self recognition.

3 carbohydrates that are crucial for self/non-self recognition.

4 se to pathogens and vaccines and in self/non-self recognition.

5 ity characterized by extensive plasticity of self recognition.

6 describe a new cell type mediating self/non-self recognition.

7 rphic receptors to perform accurate self/non-self recognition.

8 susceptible to NK cell killing upon missing self recognition.

9 ceptor T cells by overcoming NK cell missing-self recognition.

10 ivate immune signaling in the absence of non-self recognition.

11 are involved in barrier defense and self/non-self recognition.

12 cells during education for improved missing-self recognition.

13 no universal mechanisms for self versus non-self recognition.

14 cell tolerance and MHC-I-independent missing-self recognition.

15 the polymorphic S-locus determines self/non-self recognition.

16 rcinogenesis through MHC-I-dependent missing-self recognition.

17 ulation on body-awareness can be extended to self-recognition.

18 ically tractable ancient model of eukaryotic self-recognition.

19 cally irritating marks, fall short of mirror self-recognition.

20 details of nonself lipid discrimination and self-recognition.

21 gulatory requirements imposed by the risk of self-recognition.

22 phism, are ancient determinants of self-/non-self-recognition.

23 , synthetic flexibility and a capability for self-recognition.

24 ial outcomes may be related to sex-divergent self-recognition.

25 ssential metabolic enzyme enabling plant non-self-recognition.

26 represent a second system for murine NK-cell self-recognition.

27 recognition, axon fasciculation, and neuron self-recognition.

28 t the cell surface and contributes to immune self-recognition.

29 pes have shown convincing evidence of mirror self-recognition.

30 arise from an intermediate state of loss of self-recognition.

31 sification among other genes involved in non-self-recognition.

32 d substitutions, are sufficient to eliminate self-recognition.

33 ot, by themselves, be reliable indicators of self-recognition.

34 lecules within nucleoprotein filament--i.e., self-recognition.

35 riguing are phenomena associated with chiral self-recognition.

36 ed behavior (MSB) in mice, resembling visual self-recognition.

37 f-avoidance following protocadherin-mediated self-recognition.

38 e visual features of oneself is critical for self-recognition.

39 ted to cytotoxicity, IgG Fc receptor and non-self-recognition.

40 ibuting to outcross failure and leakiness in self-recognition.

41 embranes, which has been suggested to signal self-recognition.

42 ingle-cell identities that underlie neuronal self-recognition.

43 ible relationship to traditional measures of self-recognition.

44 ervariable C terminus, as a key component of self-recognition.

45 were formed, which suggests a high-fidelity self-recognition.

46 self-junctions and may be a feature of cell self-recognition.

47 ant roles in intercellular communication and self-recognition.

48 cells optimally suited for efficient missing self-recognition.

49 the killing of allogeneic cells via "missing self" recognition.

50 egulate MHC class I (MHC-I) through "missing-self" recognition.

51 e cell surface, presumably to avoid "missing self" recognition.

52 What is the basis of self recognition?

53 soform differences are sufficient to prevent self-recognition(10).

54 rent genetic mechanisms trigger death by non-self recognition and death by various environmental onsl

55 insects and has been implicated both in non-self recognition and in resistance to a variety of paras

56 tion, leveraging the weakening of fungal non-self recognition and promotion of HAVs spread.

57 insights into this biological system of non-self recognition and response activation.

58 o-polysaccharides (EPS) is important for non-self recognition and responses to microbial associated m

59 ed both genes are required for efficient non-self recognition and successful mating, as assessed by p

60 is a close connection between the Q-score of self recognition and the relative foldability (Theta) of

61 these systems function in bacterial self/non-self recognition and thereby play an important role in m

62 tions between pollen and pistil proteins as "self" recognition and/or rejection mechanisms to prevent

63 Ureas are well-known for self-recognition and aggregation behavior, resulting in

64 (TLRs) 7 and 9 exposes the host to potential self-recognition and autoimmunity.

65 acids but also introduces the possibility of self-recognition and autoinflammatory or autoimmune dise

66 Neurite self-recognition and avoidance are fundamental propertie

67 in axon and dendritic patterning and neuron self-recognition and avoidance.

68 to engage with their target, and (2) induced self-recognition and continuous CAR-mediated engagement,

69 ided insights into the mechanisms underlying self-recognition and escape from thymic deletion.

70 RNA methylation normally inhibits the self-recognition and immunogenicity of RNA.

71 her segments possibly correspond to sites of self-recognition and interaction with the other degrados

72 ings suggest a possible dissociation between self-recognition and more generalized face processing wi

73 ral patterning functions, including neuronal self-recognition and non-self-discrimination to direct s

74 dendrites and axons, demonstrating a role in self-recognition and repulsion leading to self-avoidance

75 ium between a compact form, showing specific self-recognition and resistance to proteolysis, and an e

76 ly on cell surface cues that govern cellular self-recognition and selective interactions with appropr

77 n guidance and synaptic adhesion, as well as self-recognition and self-avoidance, depending on the ne

78 la Dscam1 receptor is important for neuronal self-recognition and self-avoidance.

79 enable the fabrication of devices with both self-recognition and self-regulating functionality.

80 molecular and biochemical basis of self/non-self-recognition and self-rejection.

81 or tolerance maintenance under conditions of self-recognition and strong costimulation.

82 ls that play essential roles in establishing self-recognition and tolerance, with important implicati

83 w that the SpoIVB PDZ domain is required for self-recognition and trans cleavage of SpoIVB and is pro

84 haviors including food acquisition, self/non-self recognition, and intraspecific communication.

85 cal processes, including pathogen infection, self-recognition, and the immune response.

86 clude studies of imitation, tool use, mirror self-recognition, and the potential for attribution of m

87 sest primate relatives are capable of mirror self-recognition, and to the mechanisms that give rise t

88 activity and protein modification can direct self recognition are beginning to be unearthed.

89 Antagonistic interactions and non-self recognition are likely to promote microbial diversi

90 feature and contingency of movement cues to self-recognition are discussed.

91 (+) T cells expressing markers of heightened self-recognition are selectively retained, but not clona

92 This work brings attention to the role of "self-recognition" as a dynamic interaction between dendr

93 Kzeta knockout mice display improved missing self recognition, as evidenced by enhanced rejection of

94 rucial role of inhibitory HLA-C receptors in self-recognition, as well as NK cell education and respo

95 Our results indicate that self recognition associated with the development of MS i

96 The potential for self-recognition at a species level, and subsequent skel

97 ) T lymphocytes develop from naive cells via self-recognition at homeostasis.

98 es in their mixed solutions, demonstrating a self-recognition behavior between two highly similar mac

99 This self-recognition behavior can be explained by the slight

100 we map genetic factors underlying color and self-recognition behavior of genetic similarity in both

101 udy of the location of genes responsible for self-recognition behavior, recognition of blue color, an

102 new study finds that rhesus monkeys display self-recognition behaviors toward a mirror after multimo

103 ed natural transplantation reaction, whereby self-recognition between colonies leads to formation of

104 s an adhesion molecule in axon growth and in self-recognition between dendrites of the same neuron.

105 ined, and how these two interfaces engage in self-recognition between neuronal surfaces remains unkno

106 Self-/non-self-recognition between pollen and pistil is regulated

107 e molecules, including Dscams and Pcdhgs, in self-recognition, but repulsive molecular mechanisms rem

108 KLRG1 mediates missing self recognition by binding to a highly conserved site o

109 were later scored for behavioral indices of self-recognition by a trained observer who was blind to

110 t an initial kissing hairpin forms following self-recognition by autocomplementary RNA loops, leading

111 es from neurons, which depends on homophilic self-recognition by Dscams.

112 osed of cis and trans interactions, enhances self-recognition by increasing the concentration and sta

113 e mechanisms, driven by the need to maintain self-recognition by innate immune cells, while escaping

114 he first time, that disruption of inhibitory self-recognition can efficiently promote ADCC in a human

115 Self-recognition can often lead to repulsion, a process

116 ay play a role in the Pcdh-mediated neuronal self-recognition code.

117 protocadherin ectodomains in single-isoform self-recognition complexes, using X-ray crystallography

118 that short CDR3s increase the potential for self-recognition, conferring heightened risk of autoimmu

119 s but also decreases the formation of strong self-recognition contacts between beta-strands with high

120 Domain-swapped contacts compete with self-recognition contacts in forming various trapped sta

121 The impaired missing self recognition could not be overcome through cytokine

122 Despite this requirement for self-recognition during development, mature T cells do n

123 s shed new light into the connection between self-recognition during positive selection and recogniti

124 izing themselves in a mirror achieved mirror self-recognition earlier than infants in either a yoked

125 Here we show that post-thymic self-recognition facilitates the antigen reactivity of m

126 tion by nonexpressing flo1 cells by self/non-self recognition: FLO1(+) cells preferentially stick to

127 Because alleles at self-recognition genes are under balancing selection, th

128 s observation is consistent with deletion of self-recognition genes as a mechanism for the evolution

129 n impacts cytoplasmic organization, self/non-self recognition, genetic individuality, and perhaps eve

130 expressed in the fetus has the property of "self-recognition." Green-beard effects have many formal

131 Mirror self-recognition has been hailed by many as a milestone

132 molecular machinery, and so far, organismal self-recognition has never been described in nematodes.

133 Structural studies of missing self recognition have focused on NK receptors that bind

134 isplay CD47-although signaling mechanisms in self-recognition have remained largely unknown.

135 + cells is more pronounced in the context of self-recognition (HLA matching, indirect presentation).

136 irst in vivo evidence for MHC-independent NK self-recognition in a bone marrow rejection assay.

137 dition to using the mark test to demonstrate self-recognition in a regular mirror, we exposed six fem

138 to complex biological molecules, such as the self-recognition in dilute solutions.

139 rast, we show that the development of mirror self-recognition in human infants is a perception-action

140 1)(,)(7) One influential view is that mirror self-recognition in humans and their closest primate rel

141 rtant for cell-cell communication, molecular self-recognition in neurons, and innate immune defenses.

142 le physiological consequences of glutathione self-recognition in such processes as abnormal protein a

143 ical calculations, we investigated chirality self-recognition in the methyl lactate dimer.

144 des neurons with a unique molecular code for self-recognition in the nervous system.

145 ontribution to phagocytosis, suggesting that self-recognition inhibits contractile engulfment.

146 1B(lo) NK subset and MHC-I-dependent missing-self recognition intact.

147 Missing-self recognition involves NK cell sensing of the loss of

148 ing: in the context of the Pot1 protein, DNA self-recognition involving base-stacking and unusual G-T

149 Non-self recognition is a fundamental aspect of life, servin

150 This defect in self versus non-self recognition is also observed in other mutants where

151 Self recognition is based on allele-specific interaction

152 he question of whether a similar paradigm of self recognition is implicated in the development of mul

153 In contrast, MHC-I-dependent missing-self recognition is preserved in Nkrp1b(-/-) mice.

154 Self-recognition is a fundamental cellular process acros

155 s from those of other neurons, and that this self-recognition is essential for wiring the Drosophila

156 Self-recognition is observed abundantly throughout the n

157 sations and recall our recent actions; (iii) self-recognition; (iv) the awareness of awareness; and (

158 ion of any pathogen, it also poses a risk of self-recognition, leading to autoimmunity.

159 The high-fidelity self-recognition ligation afforded facile access to the

160 we sought to map the genomic location of the self-recognition locus (S-locus) in this species.

161 Recent studies now indicate that prion self-recognition may be an important factor in both the

162 osylation promotes non-immunogenic placental self-recognition may have relevance to immune-mediated p

163 including the Solanaceae, and this self/non-self recognition mechanism between pollen and pistil is

164 rough interactions with its prey, revealed a self-recognition mechanism acting on the nematode surfac

165 Whether this self-recognition mechanism also exists in astrocytes rem

166 This self-recognition mechanism is a novel peripheral compone

167 These roles of PAPC constitute a self/non-self-recognition mechanism that determines the site of b

168 Here we report of a self-recognition mechanism that has a novel role in moto

169 ssembly, and thus providing a size-dependent self-recognition mechanism.

170 ntial interference of plants with fungal non-self recognition mechanisms are limited.

171 These data establish that self-recognition mediated by gammaC3 contributes to astr

172 The collaborative non-self recognition model predicts that, for any S-haplotyp

173 The collaborative non-self-recognition model for S-RNase-based self-incompatib

174 dered an indicator of self-awareness, mirror self-recognition (MSR) has long seemed limited to humans

175 Specificity in plant non-self-recognition occurs either directly by perception of

176 Cell assays have demonstrated that self-recognition occurs only when all cPcdh isoforms per

177 t the distortion must be rationalized before self-recognition occurs.

178 for NKR-P1B(B6) in MHC-I-independent missing-self recognition of Clr-b in vivo.

179 Missing self recognition of MHC class I molecules is mediated in

180 le for NKR-P1B:Clr-b interactions in missing-self recognition of normal hematopoietic cells and sugge

181 loaded strongly on the probe question about self-recognition of alcohol-related problems and AD crit

182 Here, we report the chiral self-recognition of alpha-ureidophosphonates and its app

183 Upon self-recognition of beta(2)-microglobulin (beta(2)M) mol

184 ted with Crohn's disease, where breakdown in self-recognition of commensal bacteria leads to gastroin

185 In addition, phenomena related to the self-recognition of enantiomers are highly relevant in e

186 by NMR analysis, a rather unexplored form of self-recognition of enantiomers.

187 ed G-quadruplex (G4) structures form through self-recognition of guanines into stacked tetrads, and c

188 A new study has found that self-recognition of the octopus's skin by its suckers in

189 ptor-ligand system in a new form of "missing self-recognition" of tumor cells.

190 species result in mortality if there is no 'self-recognition' on a broad species level.

191 Chiral self-sorting (also known as chiral self-recognition or chiral self-discrimination) is funda

192 Cell-cycle, proliferation, death, and self-recognition pathways were altered in this radiogeno

193 a anserina participates in a fungal self/non-self recognition phenomenon called heterokaryon incompat

194 We report a self-recognition phenomenon based on an assembly process

195 mong alleles in the diploid parent determine self-recognition phenotypes of both pollen and stigma.

196 peting demands of nonself discrimination and self-recognition place limitations on the mechanisms by

197 tures, resulting in the transfer of "altered self" recognition potential among leukocyte lineages.

198 s of secondary determinants that sustain the self-recognition process during disease progression.

199 nd reflect genetic strategies for biological self-recognition processes in other species.

200 ve selection biases the repertoire away from self recognition, rather than ensuring lack of self-reac

201 s surge in proline levels attenuates the non-self recognition reaction among fungi by inhibition of c

202 omise CD47's interaction with the macrophage self-recognition receptor signal regulatory protein alph

203 tory proteins, anti-inflammatory enzymes and self-recognition receptors, and knock-down of the B4Gal

204 tory proteins, anti-inflammatory enzymes and self-recognition receptors, and knock-down of the beta4G

205 r, the design of molecules exhibiting chiral self-recognition remains challenging, and its observatio

206 Non-self recognition resulting in programmed cell death is a

207 ally, act as a bipartite module to trigger a self-recognition:self-destruct response in Arabidopsis i

208 receptors, thus perturbing induction of the self-recognition signal.

209 ) MP lymphocytes at homeostasis is driven by self-recognition signals at both the DC and Tcell levels

210 as been designed to bind at the amyloid-beta self-recognition site and prevent amyloid-beta from misf

211 ofibrils and monomers, HSA targets key Abeta self-recognition sites spanning the beta strands found i

212 stered protocadherins represents the initial self-recognition step in neuronal avoidance, and thus pr

213 he ectodomain surface, including the site of self-recognition, suggest a model for protein assembly o

214 Vegetative incompatibility is a self/non-self recognition system that inhibits virus transmission

215 complex class I (MHC-I)-independent missing-self recognition system that monitors cellular Clr-b lev

216 The simplicity of this invertebrate self-recognition system and the ubiquity of its constitu

217 A non-self-recognition system called vegetative incompatibilit

218 Thus, the P. pacificus self-recognition system enables this nematode to avoid c

219 is process is restricted by certain self/non-self recognition systems.

220 Both use 'self-recognition' systems, but their genetic control and

221 Despite self-recognition, T cells remain tolerant even in the se

222 he hallmark empirical assessment, the mirror self-recognition test, focuses on an animal's ability to

223 5 proteins has uncovered a novel mode of non-self recognition that protects against cross-species tra

224 ydroids have evolved a molecular strategy of self-recognition that is unique among characterized allo

225 that determine the exquisite specificity of self-recognition; these data suggest that direct interac

226 Because molecular specificity invokes self-recognition through protein sequence and structure,

227 ins (Saguinus oedipus) emitted indicative of self-recognition to a mirror was compared with the frequ

228 icidin mediates the process of innate immune self-recognition to enable inert nucleic acids to trigge

229 sp33 uses protein unfolding as a switch from self-recognition to high-affinity client binding.

230 The restriction of leaky self-recognition to the smallest populations is consiste

231 we presented the molecular details of sDscam self-recognition via both trans and cis interactions usi

232 We found that the consequence of self-recognition via TLR8 results in a constellation of

233 f the negative regulator CD5 correlates with self-recognition, we studied CD5(lo) and CD5(hi) naive C

234 e regions of interest (ROIs) associated with self-recognition were examined using a general linear mo

235 r in both studies, but behavioral indices of self-recognition were not consistently generated by the

236 echanism is its capacity for self versus non-self recognition when acquiring novel immune memories.

237 udicots, functions through collaborative non-self recognition, which can affect both short-term patte

238 ay a vital role in NK cell-mediated "missing-self" recognition, which contributes to NK cell activati

239 -termination model of protocadherin-mediated self-recognition, which depends on these linear chains(1

240 s is necessary and sufficient for attractive self-recognition, which is mediated by differential cell

241 Dscam isoforms on the cell surface underlie self-recognition, while the cytoplasmic tail converts th

242 Collaborative non-self recognition will usually either result in the whole

243 arly, recent work in animal tool use, mirror self-recognition (with all its contentious issues), and

244 rituximab with an Ab that blocks inhibitory self-recognition yielded increased NK cell-mediated targ