コーパス検索結果 (1語後でソート)
通し番号をクリックするとPubMedの該当ページを表示します
1 relied on isolation from natural sources and semisynthesis.
2 nucleophile of DmTR with a Sec residue using semisynthesis.
3 sual take on the age-old practice of steroid semisynthesis.
4 nal thioester are important intermediates in semisynthesis.
5 product of taccalonolide B, was generated by semisynthesis.
6 te analogue motifs in the context of protein semisynthesis.
7 expanding the scope of protein synthesis and semisynthesis.
8 ata, and some were additionally confirmed by semisynthesis.
9 d form of T beta R-I, prepared using protein semisynthesis.
10 enzoyl)paclitaxel (N-AB-PT), was prepared by semisynthesis.
11 nd C-10 acetate), a precursor for paclitaxel semisynthesis.
12 has been summarized to prepare paclitaxel by semisynthesis.
13 main obtained in our laboratory by enzymatic semisynthesis.
14 uted Arg or by other residues using chemical semisynthesis.
15 h substantially expands the scope of protein semisynthesis.
16 an only be produced recombinantly or through semisynthesis.
17 on/functionality not readily accessible from semisynthesis.
18 olated compounds and derivatives obtained by semisynthesis (9a-11) hinted at the location of the biar
19 e chemical modification of natural products (semisynthesis), a method ill-equipped to combat rapidly
23 e present study describes the application of semisynthesis and total synthesis to reveal key structur
24 igned lincosamides otherwise inaccessible by semisynthesis and underpins a platform for the discovery
27 tes the reliance on kinase-based or chemical semisynthesis approaches, making it broadly applicable t
28 thesis route is not to displace isolation or semisynthesis as a means of generating the natural produ
30 ng of E3 mechanisms, and here we use protein semisynthesis, chemical rescue, microscale thermophoresi
35 mbergris, Ambrox is produced industrially by semisynthesis from sclareol, a diterpene-diol isolated f
36 essible from natural product derivatization (semisynthesis) has resulted in the identification of a n
37 ex fermentation products, a process known as semisynthesis, has been an important tool in the discove
40 Arginylated alphaS has been studied through semisynthesis involving multipart native chemical ligati
42 a topic of great interest for over 50 years, semisynthesis is often how synthetic variants of these n
46 dge, this work represents the first reported semisynthesis of a polytopic membrane protein and highli
49 ll lysates and applied this strategy for the semisynthesis of a variety of proteins including an acet
50 r, this novel transformation facilitates the semisynthesis of a wide variety of new analogues for str
51 he analysed cocoa beans, were obtained after semisynthesis of cocoa bean polymers with (+)-catechin a
52 he first report concerning the isolation and semisynthesis of dimeric to pentameric procyanidins from
53 This technology is based on the streamlined semisynthesis of DNA-barcoded nucleosome libraries with
54 e the production yields of Taxol and for the semisynthesis of drug analogs bearing modified aroyl gro
55 single expression system, as well as by the semisynthesis of dual posttranslationally modified histo
56 tation method that bypasses the low-yielding semisynthesis of epirubicin (4'-epidoxorubicin) and 4'-e
60 licing under a range of conditions, enabling semisynthesis of modified proteins both in vitro and in
61 moieties in bilin metabolism, we report the semisynthesis of mono- and diamides of biliverdin IXalph
62 nally, the chemistry has applications in the semisynthesis of monodisperse polymers based on protein
63 we overcome this limitation by using protein semisynthesis of Na(v)1.5 in live cells and carry out co
67 sters are key intermediates in the synthesis/semisynthesis of proteins and of cyclic peptides by nati
68 ecific protein bioconjugation, synthesis and semisynthesis of proteins and peptides, and chemoproteom
70 Recent advancements in the synthesis and semisynthesis of proteins made it possible to prepare se
71 pments in the area of chemical synthesis and semisynthesis of proteins offer great solutions to the e
72 Synthetic chemists exploit inteins in the semisynthesis of proteins with or without nonribosomal m
73 ynthesis of complex disulfide-rich peptides, semisynthesis of proteins, and peptide/protein labelling
74 n, which is widely used in the synthesis and semisynthesis of proteins, has been going through severa
75 unnatural amino acid technology permits the semisynthesis of ratiometric fluorescent sensor proteins
77 ld significantly facilitate the chemical and semisynthesis of synthetically challenging proteins from
81 echnology was first demonstrated through the semisynthesis of the tick-derived chemokine-binding prot
83 otein backbone were introduced using protein semisynthesis or in vivo nonsense suppression approaches
85 gene cluster manipulation, total synthesis, semisynthesis, or a combination of these methods, with a
86 l products are almost invariably prepared by semisynthesis, or chemical transformation of the isolate
89 in ligation is a valuable method for protein semisynthesis that involves the reaction of recombinant
92 rminal tail phosphorylation, we used protein semisynthesis to insert stoichiometric and site-specific
100 ly, we demonstrate a strategy for papaverine semisynthesis using hydrogen peroxide as an oxidizing ag
101 of these chemical strategies, namely histone semisynthesis via the chemical ligation of peptide fragm
103 of planar rigidity in ordering this protein, semisynthesis was used to substitute porphyrin by two hy
105 cribe a new method to produce histone H2B by semisynthesis with an engineered sortase transpeptidase.
106 reagents for protein cyclization and protein semisynthesis, with the latter illustrated through the m