ライフサイエンスコーパス: sensing of

1 se voltammetry were performed to examine the sensing of 1-naphthol (1-N), where it was revealed that

2 Herein, we report on the enantioselective sensing of 35 amino acids, amino phosphonic acids, hydro

3 sm of the specific reaction and colorimetric sensing of 4a + Fe(3+) and 4a + Cr(3+).

4 sed, absolute radio-frequency electric field sensing of 5 muV cm(-1) Hz(-1/2).

5 We demonstrate sensing of 50-1000 ppm of vapors of ammonia and hydrogen

6 Accurate er sensing of 85 scalemic samples of Pro, Met, Cys, Ala, me

7 zer (LRO) facilitate both the generation and sensing of a leftward fluid flow.

8 MO formation reaction has been exploited for sensing of a metal ion.

9 nomous response mobilized by STING-dependent sensing of a specific vita-PAMP and elucidate how innate

10 Overall, our results reveal that cytosolic sensing of a toxin is central to the innate immune recog

11 atform feasible for high-speed and low-noise sensing of a variety of biomolecules.

12 immune signaling cascade responsible for the sensing of aberrant cytosolic double-stranded DNA (dsDNA

13 ce of GO emission is utilized to provide the sensing of acidic extracellular environments of cancer c

14 Our findings indicate that ectoIRR's sensing of alkaline conditions involves additional molec

15 ction of materials, as well as dissolved gas sensing of ammonia.

16 This is shown for selective sensing of an anti-insulin antibody in the presence of i

17 ylococcus aureus comprises the secretion and sensing of an autoinducing peptide to activate its own e

18 ilities towards online monitoring and remote sensing of analyte.

19 technique can be a promising tool for direct sensing of analytes such as drugs in body fluids, pestic

20 The binding and sensing of anions is an important cross-disciplinary fie

21 been remarkable progress in the binding and sensing of anions.

22 ensing platform was developed for the direct sensing of antibody human immuno globulin gamma (IgG) in

23 The electroanalytical sensing of APAP and INH are possible with accessible lin

24 The BiO-SPEs were evaluated toward the sensing of APAP and INH in human serum, urine, saliva, a

25 strong electrocatalytic activity toward the sensing of APAP and INH with an enhanced analytical sign

26 This 'switch' to pro-inflammatory sensing of apoptotic cells resulted from the disruption

27 signalling involved in carotid body-mediated sensing of asthmatic blood-borne inflammatory mediators.

28 Microglial sensing of ATP, the ensuing microglia-dependent producti

29 the roles of BTK in both the production and sensing of autoreactive antibodies, inhibitors of BTK ki

30 hrough the development of fast and sensitive sensing of bacteria.

31 , S. aureus(LAC), through on-chip electrical sensing of bacterial lysate.

32 We previously demonstrated that internal sensing of bacterial peptidoglycan reduces Drosophila fe

33 that enable Kretschmann-configured plasmonic sensing of bacterial toxins.

34 Here, we report that such sensing of barrier integrity leads to the rebalancing of

35 Ds (ZnO@PLP and ZnO@Py) were applied for the sensing of BAs.

36 including neural recording, stimulation and sensing of bioactive molecules at the electrode-tissue i

37 magnetic resonance imaging enable the remote sensing of biological fields.

38 l sciences as data storage can be coupled to sensing of biological molecules.

39 detection of diseases, where electrochemical sensing of biomarkers has shown considerable promise.

40 ribing and therapy monitoring; and real-time sensing of blood and/or filter effluent composition to C

41 modified protein substrates via simultaneous sensing of both chemo- and stereoselectivity; and to cre

42 nd electrons facilitated the electrochemical sensing of BPA.

43 rged as a critical mediator of innate immune sensing of cancer, and is a promising target for local i

44 For ultra-sensitive sensing of CEA with great specificity and accuracy, an i

45 Electrical impedance-based sensing of cell activity has become a powerful analytica

46 by the hydrogels, these results reveal cell sensing of cell volume confinement as an adhesion-indepe

47 thermore, TLR2 but not TLR4 was critical for sensing of cell wall extracts and whole corynebacteria.

48 es and inflammasomes can be triggered by the sensing of cellular stress, they drive contrasting cell-

49 mechanotransduction pathways that facilitate sensing of changes in mechanical cues by tissue resident

50 l of the expression of regulatory microRNAs, sensing of changes in the environment by use of riboswit

51 pathogens, but acquisition of nutrients and sensing of changes in the host cell bring new challenges

52 the SCS and by potentially enhancing T cell sensing of chemokine gradients.

53 ng in humans by utilizing non-contact camera sensing of Cherenkov emission during the radiation thera

54 amework systems as a useful method for rapid sensing of chiral molecules.

55 to show simple colorimetric enantioselective sensing of chiral species with a fast readout in less th

56 Using optical sensing of chloramphenicol as a proof of concept, we sho

57 These results reveal innate immune sensing of circRNA and highlight introns-the predominant

58 x 10(-9)M, indicating its potential for the sensing of COD in clinical samples and pharmaceutical fo

59 ellent electrocatalytic response towards the sensing of COD with a wide linear response range of 2.0

60 electrocatalyst toward the electroanalytical sensing of codeine phosphate (COD).

61 uggest that the wound signaling involves the sensing of collapse of damaged cells and a local auxin s

62 Thus, sensing of commensals by Mincle and Syk signaling in CD1

63 Molecular hosts capable of chiroptical sensing of complexed guest molecules offer an attractive

64 nthetic gene networks, the fast and portable sensing of compounds, on-demand biomanufacturing, buildi

65 Host sensing of corynebacteria is largely uncharacterized, al

66 of the advantages of current methods of (bio)sensing of creatinine, as well as an overview of the dra

67 The limit of detection for chemical sensing of Crystal Violet and Rhodamine 6G by the Al-QS

68 Biological sensing of cysteine, a disease biomarker and carcinoembr

69 the emerging literature on regulation of the sensing of cytosolic DNA and RNA via cGAS and RLRs.

70 ere we review the emerging literature on the sensing of cytosolic LPS and its regulation and pathophy

71 Sensing of cytosolic nucleotides is a critical initial s

72 he electrochemical detection/electrochemical sensing of DA.

73 Using satellite remote sensing of deformation, gas emissions and thermal anomal

74 Sensing of distinct nutritional signals can drive P. fal

75 old nanozymes have been used in detection or sensing of diverse analytes such as clinical biomarkers,

76 tudied and documented in detail, whereas the sensing of DNA in cytosolic compartment in human pDCs re

77 owed by Toll-like receptor 9 (TLR9)-mediated sensing of DNA in phagosomes.

78 rofound influence of selective and sensitive sensing of DNA molecules in disease diagnosis and molecu

79 (rGO) based impedimetric sensor for one step sensing of DNA.

80 idelity, achieved by label-free simultaneous sensing of DNA/RNA, hemoglobins, and lipids.

81 electrocatalyst toward the electroanalytical sensing of dopamine (DA).

82 ted carbon electrode for the electrochemical sensing of dopamine and epinephrine.

83 The electrochemical sensing of dopamine is of great significance for studyin

84 ts in vivo/in vitro applications in clinical sensing of dopamine.

85 the type I IFN pathway, which comprises the sensing of double-stranded RNA and DNA (dsRNA/dsDNA) fol

86 ffect is mainly attributed to MDA5 and RIG-I sensing of double-stranded RNAs (dsRNAs).

87 These results show that the sensing of dsRNA is critical for loss of cell-specific g

88 dimensional mapping of the axon diameter and sensing of dynamic changes in the substructure of myelin

89 gated bile acids and demonstrated intestinal sensing of elevated bile acid levels in plasma in mice.

90 carries out A-to-I editing of RNA to prevent sensing of endogenous double-stranded RNAs.

91 Here we show that Zalpha-dependent sensing of endogenous ligands induces ZBP1-mediated peri

92 These findings indicate that dysregulated sensing of endogenous nucleic acid by ZBP1 can drive inf

93 ucleic acid-binding activity, we report that sensing of endogenous nucleic acids by ZBP1 is critical

94 ively, our results provide evidence that the sensing of endogenous Z-form nucleic acids by ZBP1 trigg

95 Although the sensing of endoplasmic reticulum (ER) Ca(2+) stores by S

96 suggesting that YopK limits the induction or sensing of endosomal membrane damage by components of th

97 a novel route to signal transduction for the sensing of energetic materials.

98 When pathogens enter the host, sensing of environmental cues activates the expression o

99 s of two-component systems, which couple the sensing of environmental stimuli to adaptive responses.

100 ood at the molecular level about the initial sensing of environmental stress.

101 teractions Lamellipodin mediates directional sensing of epidermal growth factor (EGF) gradients and i

102 However, real-time sensing of explosives still possesses a huge analytical

103 Cell sensing of externally applied mechanical strain through

104 Sensing of extracellular adenosine triphosphate (eATP) b

105 IFN-I response, and they illustrate how the sensing of extracellular damage-associated molecular pat

106 Evidence in plants supports the sensing of extracellular DNA by PRRs, leading to calcium

107 the usage of different integrin subtypes and sensing of extracellular matrix proteins.

108 litary tract) and central through the direct sensing of extracellular protons.

109 surface of most cells, are important to the sensing of extracellular signals, and make a driving for

110 s source of FA in the cell by activity-based sensing of FA fluxes perturbed via ALKBH5 knockdown.

111 used for the highly selective and sensitive sensing of ferric ions (Fe(3+)).

112 Thus far, NV sensing of ferromagnetic dynamics has been constrained t

113 n elegant navigational strategy based on the sensing of flow velocity gradients and provide a compreh

114 This approach for colorimetric sensing of fluoride by ring-opening of the otherwise pho

115 ty and enhanced reduction signal towards the sensing of fluvoxamine.

116 nterferon and proinflammatory responses upon sensing of foreign DNA.

117 abricated on an electrode for optoelectronic sensing of fowl adenoviruses (FAdVs).

118 s K(d) = ~3 uM, which is consistent with the sensing of 'free' iron in the cytoplasm.

119 to real-time agricultural and environmental sensing of fungal symbionts and pathogens.

120 frequency gas detector that can be used for sensing of gas mixtures with high selectivity, accuracy,

121 (MOFs) as active materials in chemiresistive sensing of gases.

122 e to their genome integrity by AhR-mediated 'sensing' of genotoxic compounds from the diet.

123 carbon paste matrix and was utilized for the sensing of glucose in food products.

124 nitoring, as well as selective and sensitive sensing of glucose in mammalian blood.

125 Automated amperometric sensing of glucose solutions in microtiter-plate wells u

126 o broaden the application of electrochemical sensing of glucose, we fabricated, for the first time, a

127 Moreover, in vitro glucose sensing of glucose-inhibitory neurons from the ventromed

128 tein core, we show activity-based, amplified sensing of glucose.

129 We demonstrate the sensing of H(2)S, CH(4), CO(2), CO, NO, CH(2)O, NO(2), S

130 usceptibility locus; and RPTPgamma-dependent sensing of HCO(3)(-) adjusts endothelium-mediated vasore

131 fordable system for real-time monitoring and sensing of heavy metals.

132 erization-based signal amplification for the sensing of hemoglobin, as the analyte catalyzes the form

133 n natural HIV infection modulated normal pDC sensing of HIV.

134 The mechanisms at the basis of the sensing of humidity in the device were investigated by c

135 Selective and sensitive electrochemical sensing of hydrogen peroxide was carried out at -100 mV

136 To determine if the sensing of hypoxia by nonclassical monocytes contributes

137 Here, we report that the sensing of IAV RNA by retinoic acid inducible gene I (RI

138 Last decades, electrochemical sensing of illegal drugs has experienced a very signific

139 We found that innate sensing of incoming virus and the ensuing type I interfe

140 In cells, sensing of increased levels of reactive oxygen species (

141 host defense pathway is orchestrated by the sensing of infection by DAI/ZBP-1, engagement of the kin

142 Fpr3 has been implicated in the sensing of infection-associated olfactory cues, but its

143 roles of NOD1 and NOD2 to encompass not only sensing of infections with viruses and parasites but als

144 Sensing of inflammatory cytokines, which also include TN

145 Innate sensing of influenza virus infection induces activation

146 ory checkpoints such as ADAR1 that limit the sensing of innate ligands.

147 ld be implemented in other systems and drive sensing of integrity and response by regeneration in oth

148 triggers immune activation, suggesting that sensing of iron depletion is a mechanism by which plants

149 lytical device (EmuPADs) for electrochemical sensing of ketamine.

150 RET) copper probe, FCP-1, for activity-based sensing of labile Cu(I) pools in live cells.

151 biosensor for minimally invasive continuous sensing of lactate in the dermal interstitial fluid (ISF

152 PECT-MP for improving capabilities of remote sensing of leaf photosynthetic pigments (chlorophyll a,

153 Our approach combines direct wavefront sensing of light from a guidestar (formed by descanned f

154 excellent anchoring capabilities is used for sensing of light, gas, molecules, and strain.

155 ickness behaviors but required hematopoietic sensing of lipopolysaccharide (LPS) via the toll-like re

156 sepsis via Toll-like receptor 4 (TLR4)/MyD88 sensing of lipopolysaccharides.

157 optical waveguides used for evanescent field sensing of liquid chemical and biological samples for MI

158 the VP5 anchoring domain alone recapitulates sensing of low pH.

159 uncover a model in which direct periplasmic sensing of LPS by PbgA coordinates the biosynthesis of l

160 nate immune receptors have a key role in the sensing of malaria and initiating immune responses.

161 This was found to occur not through direct sensing of MDP by DCs themselves, but rather via the pro

162 f Thr172 phosphorylation.AMPK is involved in sensing of metabolic stress.

163 of PA contrast agents as biosensors (in the sensing of metal ions, pH, enzymes, temperature, hypoxia

164 cellent electrocatalytic activity toward the sensing of Metol (LOD, 0.009 muM; sensitivity, 2.397 muA

165 Infra-red (IR) sensing of mice was used to monitor spontaneous activity

166 This immune layer involves sensing of microbe-associated molecular patterns (MAMPs)

167 oth locally and systemically, requires tonic sensing of microbes and complex feedback loops between i

168 1-activating multiprotein complex that links sensing of microbial and stress products to activation o

169 Sensing of microbial DNA through these receptors stimula

170 Smartphone image-based sensing of microfluidic paper analytical devices (muPADs

171 In resistive pulse sensing of microRNA biomarkers, selectivity is achieved

172 Optimal quantitative sensing of miR-141 was achieved via the first example of

173 ectives for the design of amplified sensors (sensing of miRNA-376a) and the development of logic gate

174 tive ionophores dedicated to electrochemical sensing of molecular ions.

175 ing," achieves robustness by combining local sensing of morphogen levels with global modulation of gr

176 ucleic acids and how these assemblies enable sensing of multiple distinct features in foreign nucleic

177 The integration of sensing of multiple stress conditions and subsequent sig

178 ture mRNA is facilitated by the simultaneous sensing of multiple, spatially distant mRNA regions and

179 rystal microbalance sensor was developed for sensing of Mycobacterium leprae bacteria through its epi

180 of the R753Q TLR2 polymorphism on macrophage sensing of Mycobacterium smegmatis Upon infection with M

181 molecular pattern that may facilitate immune sensing of myeloma tumors and modulate the tolerogenic c

182 y be widely relevant in long-term biological sensing of naturally fluctuating temperatures.

183 We hypothesized that sensing of necrotic cells by DNGR-1 plays a determinant

184 Real-time sensing of nitric oxide (NO) in physiological environmen

185 ll AIEgens are fruitfully employed for rapid sensing of nitroaromatic compounds (NACs) where picric a

186 uit, the sensor platform achieves continuous sensing of NO levels in living mammals for several days.

187 nanoporous structure for the electrochemical sensing of NO, which was fabricated via a facile electro

188 Cytosolic sensing of nucleic acids initiates tightly regulated pro

189 The innate sensing of nucleic acids remains the major initiating fa

190 stages, and to optimize the platform for the sensing of nucleic acids using a paper-based detection m

191 TLR-mediated sensing of nucleic acids via endosomal pathways has been

192 ed KIN as a critical regulator that mediates sensing of nutrients and controls a transcriptional resp

193 vior, confirming that TYRA-2 partakes in the sensing of osas#9.

194 ultaneous spatiotemporal tracking and oxygen sensing of other cell populations and biomaterials that

195 The sensing of oxygen availability through the Cys/Arg N-deg

196 ly dependent on qualitative and quantitative sensing of P. aeruginosa quorum.

197 e Vgamma9Vdelta2 T cell response begins with sensing of pAg via the intracellular domain of the butyr

198 tured aptasensor for label free impedimetric sensing of pathogenic bacteria E. coli O78:K80:H11.

199 nts with nanomaterials for the detection and sensing of pathogenic bacteria.

200 a-induced pathways involved in innate immune sensing of pathogens and antimicrobial responses argue f

201 Cytosolic sensing of pathogens and damage by myeloid and barrier e

202 The sensing of pathogens by macrophages engages conserved si

203 Sensing of pathogens by Toll-like receptor 4 (TLR4) indu

204 These data provide a link between sensing of peripheral cancer initiation by the bone marr

205 on methods and materials for use in optical sensing of pH values and on applications of such sensors

206 ue, a brief look back on optical methods for sensing of pH, on the effects of ionic strength on pH va

207 ies that these devices have for the advanced sensing of pharmaceutical compounds toward safeguarding

208 e mediated by the same cellular pathway, but sensing of physical stimuli remains poorly understood.

209 Accurate and reliable real-time sensing of physiological information using wearable bios

210 Interoception is the sensing of physiological signals originating inside the

211 eloped to facilitate sensitive and real-time sensing of picric acid.

212 Phytopathological aspects of remote sensing of plant diseases across different scales and fo

213 nd the rapid advances in proximal and remote sensing of plants in fields.

214 In mouse T cells, cGAS KO ablated sensing of plasmid DNA, and TREX1 KO enabled cells to se

215 CDS are devoid of >4 consecutive AAA codons, sensing of prematurely placed polyA tails by a specializ

216 e-based probe has been applied for chirality sensing of primary amines.

217 The capacity for multiplexed sensing of protease activity was demonstrated using thes

218 FET (ImmunoFET) for specific and label-free sensing of proteins through antigen-antibody interaction

219 be the characterization of nanopore blockade sensing of PSA by (1) tuning on/off the electromagnet, (

220 ly facilitates active delivery and selective sensing of PSA to the nanopore.

221 ovel neutrophil activation pattern upon FPR2 sensing of PSMalpha peptides, signified by the ability t

222 Sensing of red and far-red light by bacteriophytochromes

223 omatal opening arises from direct guard cell sensing of red light versus indirect responses as a resu

224 oligonucleotides strongly potentiating TLR8 sensing of Resiquimod, which preserve TLR7 function, and

225 nables acute myeloid leukemia cells to evade sensing of retrotransposons by innate immune receptors.

226 biquitination resulted from ZNF598-dependent sensing of ribosome collisions initiating RQC, another m

227 ss initiated by the E3 ligase ZNF598 through sensing of ribosomes collided at aberrant mRNAs and mono

228 Sensing of S1 and RBD antibodies is specific, which cros

229 that this demonstrates the first large-scale sensing of sarcomere dynamics in vivo, which is a necess

230 ious agents while avoiding the inappropriate sensing of self-DNA.

231 We found that GC B cell-intrinsic sensing of self-RNA, but not self-DNA, released from dea

232 Thus, immunoreceptor sensing of SFK activity is a complex process regulated a

233 ging: fully automated tracking and proximity sensing of small animals, even in closed habitats, at hi

234 ansitions providing multimodal and multiplex sensing of small biotargets, such as proteins and viruse

235 Here, we used host sensing of small molecules by G-protein coupled receptor

236 regulatory elements that directly couple the sensing of small molecules to gene expression.

237 teleost fish brain and connects it to active sensing of spatial environmental features.

238 yle of metabolic regulation enables pathogen sensing of specific nutrients to engage them into catabo

239 regulatory mechanisms underlying intestinal sensing of specific nutrients, especially micronutrients

240 ed atomic-scale spatial resolution in remote sensing of spins may ultimately allow the structural ima

241 dance with respect to circadian time, or the sensing of sugars to feedback to the circadian oscillato

242 phone app for non-invasive and in situ multi-sensing of sweat biomarkers including glucose, lactate,

243 The sensing of target cells, thought to be mediated by the d

244 ) O(2) in the aqueous droplets, exemplifying sensing of targets beyond ionic species.

245 AhR sensing of TB drugs modulates host defense mechanisms, n

246 ltifunctional sensor capable of simultaneous sensing of temperature, pressure, and proximity has been

247 Quantitative chirality sensing of terpenes and terpenoids exhibiting a single d

248 odies from the antigens, allowing successive sensing of test samples using the same sensor.

249 m cell generation by enhancing CD8(+) T cell sensing of TGF-beta, which was necessary for tissue resi

250 es a more reliable, selective and controlled sensing of the analyte.

251 ls, suggesting that recognition occurred via sensing of the cancer metabolome.

252 Finally, the sensing of the chemosensor HMBP for the determination of

253 structure-specific enzymes driven by protein sensing of the conformational dynamics of their DNA subs

254 n contact with necrotic tissue that requires sensing of the damage signal ATP.

255 least in part to an efficient and continuous sensing of the environment, with a ready-to-adapt strate

256 ology, and function can be modulated by cell sensing of the extracellular environment through mechano

257 ology, and function can be modulated by cell sensing of the extracellular environment through MSCs an

258 We find that necroptosis requires sensing of the genomic RNA within incoming virus particl

259 This previously unexpected cytosolic LPS sensing of the innate immune system provides critical hi

260 Missing-self recognition involves NK cell sensing of the loss of host-encoded inhibitory ligands o

261 Toll-like receptor (TLR)-mediated sensing of the microbiota contributes to gut homeostasis

262 s pathway involves MYD88- and NOD2-dependent sensing of the microbiota.

263 ral F-actin-rich structures that enable cell sensing of the microenvironment.

264 pin 1, the PBD is the site of PA binding and sensing of the PA electrostatic charge.

265 n human malaria, including studies of innate sensing of the parasite, immunometabolism, and innate im

266 Upon sensing of the peptide pheromone cCF10, Enterococcus fae

267 Proprioceptive sensing of the position of rigid joints has been describ

268 using the tip for simultaneous delivery and sensing of the reaction rate.

269 igh as approximately 40 and refractive index sensing of the surrounding medium as high as 1245 nm/RIU

270 ne network exhibits reduced crosstalk in the sensing of the two different ROS.

271 ial in pDCs but not in cDCs, indicating that sensing of the viral genome by pDCs activates cDCs in tr

272 ZBP1 sensing of the Z-RNA produced during influenza virus inf

273 Sensing of these biomarkers can simultaneously help in u

274 The sensing of these compounds is important but challenging.

275 The sensing of these nutrients, as well as the perception of

276 Targeted interruption of pathogen sensing of these small molecules could therefore attenua

277 Thus, ribosomes connect the sensing of this fungal PAMP to the activation of an inna

278 to reveal the early events in the cytosolic sensing of this nucleic acid in a myoblast cell line.

279 Direct sensing of TLR agonists by CMP induced rapid proliferati

280 thus enabling tunable thermo-mechanochromic sensing of touch and strain.

281 It also gives rise to direct sensing of triacetone triperoxide (TATP) explosive throu

282 In this work, we study the role in pH sensing of two regions of the ectodomain enriched in aci

283 l-rich pore surfaces for the recognition and sensing of two representative PCDDs, 2,3-dichlorodibenzo

284 gh their application in competitive affinity sensing of uncharged small molecules is still hindered b

285 We highlight the sensing of upcoming biomarkers, including microRNA, circ

286 latform, offering simple and straightforward sensing of uranyl levels in urine, suitable for field de

287 Continuous sensing of uric acid was also performed using this biose

288 Early sensing of viral components or infection-induced tissue

289 tionally connects capsid stability to innate sensing of viral DNA and reveals naturally occurring phe

290 ability that has a profound effect on innate sensing of viral DNA by the DNA sensor cGAS.

291 ion does not appear to trigger cGAS-mediated sensing of viral DNA in T cells, possibly by revealing v

292 The sensing of viral nucleic acids by the innate immune syst

293 eptor in an inactive state and attenuate its sensing of viral RNA (vRNA).

294 codes an RIG-I-like receptor involved in the sensing of viral RNA.

295 expression following cytosolic nucleic acid sensing of viruses, their contribution to innate immune

296 mmunoassays, detection of microorganisms, to sensing of viruses.

297 related to abnormal interoception (i.e., the sensing of visceral feelings), as observed in patients w

298 his platform opens new avenues for real-time sensing of volatile chemical compounds, odors, and flavo

299 tion of an MOF coating opens the way for the sensing of volatile organic compounds (VOCs) in gaseous

300 lds including scanning probe microscopy, the sensing of weak forces, the measurement of atomic masses