ライフサイエンスコーパス: sensitive assay

1 both a standard and a pre-commercial highly sensitive assay.

2 B cells every 3 months with a novel, highly sensitive assay.

3 value of -0.2 obtained from data with a less sensitive assay.

4 ripheral leukocytes was detected by a highly sensitive assay.

5 tect any WHx protein in the cells by using a sensitive assay.

6 in addition to the O157 serotype by using a sensitive assay.

7 rus (HBV) infections are highly specific and sensitive assays.

8 tectable in normal aging epithelium by using sensitive assays.

9 urable viral suppression, as defined by very sensitive assays.

10 tent low-level viremia is detected with more sensitive assays.

11 ions of immunoreagents resulting in the most sensitive assays.

12 arily due to a lack of appropriate tools and sensitive assays.

13 Aquaporin 4 antibodies were tested using 2 sensitive assays.

14 In the most sensitive assays, 9 of 11 volunteers and 5 of 8 Ty21a co

15 In addition, such a highly sensitive assay allows discrimination of drug-induced re

16 This highly sensitive assay allows us to determine the endogenous le

17 resulted in the development of increasingly sensitive assays, an enhanced appreciation of the pharma

18 levels of virus can be detected in plasma by sensitive assays and transient episodes of viremia, or H

19 etic resonance imaging (MRI), cTnT by highly sensitive assay, and NT-proBNP analysis (n = 2,413).

20 en for 31 days) on serum CRP, using a highly-sensitive assay, and on serum platelet-cyclo-oxygenase (

21 often detectable in community dwellers when sensitive assays are applied.

22 Highly sensitive assays are critical for early detection of cha

23 New sensitive assays are currently available for the detecti

24 Sensitive assays are essential for the accurate identifi

25 Sensitive assays are needed for detection of residual hu

26 ower than plasma levels, accurate and highly sensitive assays are needed for saliva measurements.

27 pecially from small clinical samples, highly sensitive assays are required.

28 which confirms the importance of using this sensitive assay as an initial screen in vaccine protocol

29 rior HF who had cTnT measured using a highly sensitive assay at baseline (1989-1990) and repeated aft

30 The ATPase activity is characterised using a sensitive assay based on a chemically modified form of t

31 Using a sensitive assay based on betagamma complex stimulation o

32 Receptor binding was measured initially by a sensitive assay based on coexpression of receptor and RB

33 A sensitive assay based on competition between cis-and tra

34 We developed a sensitive assay based on self-assembling radiolabeled te

35 A sensitive assay based on single lipid tracking experimen

36 mass spectrometry has produced accurate and sensitive assays, but chromatographic separations requir

37 in developing a high-throughput specific and sensitive assay by including a deep knowledge of the phy

38 This rapid and sensitive assay can be used to identify enterotoxigenic

39 The most sensitive assay can detect as few as two copies of HPV D

40 This sensitive assay can measure rates of DNA methylation dow

41 ing the local particle concentration, highly sensitive assays can be performed efficiently and rapidl

42 oughput sequencing (cfMeDIP-seq) is a highly sensitive assay capable of detecting early-stage tumors.

43 be the modification and development of three sensitive assays capable of detecting nanogram quantitie

44 MethyLight is a highly sensitive assay, capable of detecting methylated alleles

45 This nanopore-based methylation sensitive assay circumvents the need for bisulfite conve

46 Using the most sensitive assay combination, we measured TCS concentrati

47 A highly sensitive assay combining immunomagnetic enrichment with

48 Using a novel high-sensitive assay, cTnI levels could be determined in near

49 Overall, the results suggest that more sensitive assays (e.g., ELISPOT, ELISA analysis of cytok

50 We report a rapid, specific, and sensitive assay employing isothermal DNA amplification u

51 anogels ("plastic antibodies") with a highly sensitive assay employing templates attached to magnetic

52 Using two sensitive assays (enzyme-linked immunospot assay and int

53 Using this sensitive assay, Escherichia coli tail-specific protease

54 spread from cell to cell, even though highly sensitive assays fail to detect infectious virus progeny

55 Using a sensitive assay for activated Ras, we show here that act

56 exchange has been developed into a rapid and sensitive assay for both SHMT and H4PteGlun and the one-

57 A sensitive assay for competitive binding of dinucleosome

58 -4-methylcoumarin (AzMC), serves as a highly sensitive assay for cystathionine beta-synthase activity

59 dy design and analysis, the Morris maze is a sensitive assay for detecting AD-relevant impairments ac

60 Significantly, a label-free sensitive assay for detecting carcinoembryonic antigen (

61 A sensitive assay for detecting double-stranded (ds) DNA i

62 erefore, may be used as part of a robust and sensitive assay for detecting not only purified, but als

63 To develop a highly sensitive assay for detecting the cellular immune respon

64 We describe a sensitive assay for detection of active hyaluronan synth

65 RT-QuIC, like IHC analysis, is a relatively sensitive assay for detection of CWD prions in RAMALT bi

66 s a primer for PCR represents a specific and sensitive assay for detection of H. pylori in highly con

67 nPCR was the most sensitive assay for detection of malaria in pregnancy, f

68 of these volatiles because of the lack of a sensitive assay for DMAPP in plant tissues.

69 gamma-H2AX nuclear foci, considered the most sensitive assay for DNA DSBs.

70 Here we present a sensitive assay for DNA transesterification in which cat

71 In conclusion, a sensitive assay for exposure to tri-o-cresyl phosphate w

72 Furthermore, using a sensitive assay for glucose 6-P in hydrolysates of glyco

73 In this study, using an extremely sensitive assay for hCG, 10% of clinical pregnancies wer

74 tation of a homogeneous, miniaturizable, and sensitive assay for histone methylation-dependent intera

75 In addition, development of a highly sensitive assay for I in human plasma at low picogram pe

76 prohead oligomers also provides a rapid and sensitive assay for identification and analysis of porta

77 ther tests of species-typical behavior, is a sensitive assay for identifying previously unknown behav

78 r results suggest that CaAR can be used as a sensitive assay for INF2 function and for robust evaluat

79 We have used a sensitive assay for MAP kinase activity to investigate t

80 A convenient, sensitive assay for measurement of in vivo missense tran

81 system based on vitamin B12 auxotrophy as a sensitive assay for metabolite exchange between marine p

82 we report a simple, inexpensive, and highly sensitive assay for MMP activity.

83 We have developed a highly sensitive assay for monitoring the metastatic disseminat

84 ere we report the development of a rapid and sensitive assay for NRD convertase, based on the utiliza

85 Tg.AC transgenic mice provide a sensitive assay for oncogenic agents and a convenient al

86 ressed PIP(2)-dependent Kir2.1 channels as a sensitive assay for PLC activity, we show that simple gl

87 Sensory fMRI can provide a sensitive assay for probing the nature and function of S

88 omplementation provides a rapid, simple, and sensitive assay for protein interactions and for detecti

89 use of the strategy allowed us to develop a sensitive assay for proteins with three appealing featur

90 A sensitive assay for quantitating DNA damage within indiv

91 paper substrate provides a new, simple, and sensitive assay for rapid detection of blood group for p

92 ing highly resistant to BG, but the use of a sensitive assay for reaction of BG with AGT indicated th

93 This specific, sensitive assay for SEB on the portable fiber-optic bios

94 vs 97% at week 96, P = .002), despite a more sensitive assay for seminal plasma than for cervical wic

95 treatments with goserelin and exemestane, a sensitive assay for serum estradiol was checked and retu

96 This protocol was evaluated using a sensitive assay for spontaneous branch migration, and wa

97 varies across these conditions, providing a sensitive assay for TARP/AMPAR stoichiometry.

98 We have developed a sensitive assay for the AMP-activated protein kinase kin

99 A new, sensitive assay for the deformylase has been developed b

100 AMPLICOR CMV Test could provide a rapid and sensitive assay for the detection of CMV in plasma and C

101 Here we present a rapid, simple and sensitive assay for the detection of epidermal growth fa

102 Here we describe a sensitive assay for the determination of plasma homocyst

103 Here I describe a new sensitive assay for the determination of protein N-linke

104 tern blot assay still appears to be the more sensitive assay for the diagnosis of HIV-1 infection in

105 There is major need for a more sensitive assay for the diagnosis of pneumococcal commun

106 li cells are limited by the lack of a rapid, sensitive assay for the DNA damage that results.

107 itor could serve as the basis of a rapid and sensitive assay for the early detection and for the surg

108 his process, we developed a quantitative and sensitive assay for the induction of erythroid cells fro

109 the elements of H(3)PO(4) (98 Da) provides a sensitive assay for the presence of phosphopeptides.

110 f centromere dynamics in G1 yeast cells as a sensitive assay for the regulation of single k-MT dynami

111 We implemented a novel, extremely sensitive assay for the release and transfer of anterogr

112 The new reagents provide the most sensitive assay for the three lysosomal enzymes reported

113 f these heme adducts, we sought to develop a sensitive assay for their detection and quantitation.

114 cles coated with our aptamers as a rapid and sensitive assay for these compounds.

115 formation of VA2 muscle precursor cells as a sensitive assay for these genetic interaction studies.

116 othrombin F-1 x 2 concentrations, and a less sensitive assay for under-gamma-carboxylated prothrombin

117 nhancement in fluorescence, thus providing a sensitive assay for use in vitro and in vivo.

118 r reliable high-throughput, rapid and highly sensitive assays for a simultaneous detection of several

119 The development of highly sensitive assays for biochemical detection of PrP(Sc) in

120 Sensitive assays for coagulation activation have provide

121 tion provides a new platform of low cost and sensitive assays for cotinine detection.

122 Accordingly, sensitive assays for detecting Bcr-Abl kinase activity c

123 vation during immune responses, we have used sensitive assays for detecting native IL-15 and IL-15Ral

124 Sensitive assays for DSB-dependent homologous recombinat

125 Sensitive assays for HBV DNA levels in serum have been d

126 ed for the development of rapid, facile, and sensitive assays for histamine detection suitable for po

127 More sensitive assays for human immunodeficiency virus type 1

128 Currently available proximity-sensitive assays for in situ imaging of such interaction

129 Moreover, sensitive assays for KSHV ORF65-specific and ORF73-speci

130 Molecular tools are highly sensitive assays for Leishmania detection and may contri

131 direct range of Shh signalling, we developed sensitive assays for localizing Shh by attaching alkalin

132 The availability of sensitive assays for plasma HIV viral load and the trend

133 Sensitive assays for rapid quantitative analysis of hist

134 developed in the 1970s involving especially sensitive assays for RT as a surrogate marker for a retr

135 Xpert Xpress SARS-CoV-2 assays were the most sensitive assays for SARS-CoV-2 with 100% agreement acro

136 We describe a variety of sensitive assays for SFV isolation and detection which w

137 urine has several preanalytic drawbacks, and sensitive assays for the detection of uromodulin in bloo

138 The widespread use of sensitive assays for the detection of viral and cellular

139 ratio, allows for the development of highly sensitive assays for the determination of miRNA in a var

140 Widespread use of automated sensitive assays for thyroid hormones and thyroid-stimul

141 as a biothreat agent has made development of sensitive assays for toxin detection and potent antitoxi

142 The most sensitive assay from the screening studies [coating anti

143 ukocyte PCRs (L-PCR and L-AMP) were the most sensitive assays, had positive results an average of bet

144 A sensitive assay has been developed to quantitate fibrino

145 of CD4(+) T cells in vitro, but the lack of sensitive assays has limited its application for studyin

146 tion of very low troponin levels with highly sensitive assays has made feasible several potential new

147 Rapid advances in ultra-sensitive assays have enabled the levels of pathological

148 ctrophoresis or dot blot hybridization, is a sensitive assay; however, at this time it cannot complet

149 We measured cardiac troponin T with a highly sensitive assay (hs-cTnT) at 2 time points, 6 years apar

150 of cardiac troponin T, measured by a highly sensitive assay (hs-cTnT), are strongly associated with

151 diomyocyte injury, were measured by a highly sensitive assay (hsTnT) in 4,431 ambulatory participants

152 The most sensitive assay identified was one utilizing antiserum n

153 Low-level increases in cTnI using a sensitive assay identify patients at higher risk of deat

154 I (cTnI) was measured by using a novel, high-sensitive assay in community dwellers aged 70 years from

155 troponin I (cTnI) using a current-generation sensitive assay in patients with suspected acute coronar

156 Measurement of estradiol level by sensitive assay in postmenopausal women identifies those

157 nant enzyme was characterized using a highly sensitive assay in the presence and absence of the propo

158 sured using both the standard and the highly sensitive assays in 3546 individuals aged 30 to 65 years

159 MI, and the incremental value of newer, more sensitive assays in identifying high-risk patients with

160 versity, and the influence of novel and more sensitive assays in the detection and analysis of signal

161 Recent modifications of this sensitive assay include elimination of radioactivity by

162 Novel algorithms with highly sensitive assays, incorporating baseline troponin values

163 We used a sensitive assay involving biotinylation to show that all

164 For these latter studies, we used a sensitive assay involving the infusion of highly purifie

165 The sensitive assay is based on the close to absolute electr

166 This sensitive assay is ideal for kinetic analysis of Tdp1 fu

167 pg/mL (61 pmol/L); postmenopausal range for sensitive assay is less than 15 pg/mL (< 50 pmol/L).

168 This is especially the case when a very sensitive assay is required to differentiate often highl

169 cal significance of low-level increases with sensitive assays is still debated.

170 These findings support the use of more sensitive assays, like NAT, in HIV screening of populati

171 This highly sensitive assay may be used to determine accurately less

172 These rapid sensitive assays may have potential use in clinical sett

173 between the various treatment groups, 2 more sensitive assays measuring antigen-specific interferon-g

174 Based on tetramer binding and two sensitive assays measuring interferon-gamma production a

175 A nonradioactive, sensitive assay method to evaluate the activity of prote

176 colon cancer, along with easier-to-use, more sensitive assay methods, may improve the detection, trea

177 inefficient process and therefore provides a sensitive assay of altered opioid receptor function and

178 ptic mechanisms of attention, we developed a sensitive assay of attentional modulation of neuronal co

179 We describe a sensitive assay of chromatin structure which is performe

180 the antisaccade task, which is considered a sensitive assay of cognitive function, a salient visual

181 Using a robust, sensitive assay of KIR binding and a representative pane

182 by hydrolysis of lipoyl-N-epsilon-lysine, a sensitive assay of lipoamidase activity was developed ba

183 We report a practical, nonradioactive, sensitive assay of MCD in crude tissue extract.

184 These approaches are based on the sensitive assay of molecular markers in stool, blood, an

185 Using an accurate and sensitive assay of parasite genotype, real-time quantita

186 ERG timing is a sensitive assay of retinal function, and our results ind

187 We have developed a highly sensitive assay of RNA interference (RNAi) in mammalian

188 A sensitive assay of the 2H-enrichment of water based on t

189 A highly sensitive assay of tRNA aminoacylation was developed tha

190 Salmonella) had immune responses in the most sensitive assay of urease-specific immunoglobulin produc

191 Sensitive assays of biochemical specificity, affinity, a

192 Using sophisticated mass spectrometry and sensitive assays of disease-relevant toxicity we show th

193 eport the development of a set of robust and sensitive assays of human SIX3 function in zebrafish and

194 eficiency virus (SIV) infection by using the sensitive assays of intracellular cytokine staining and

195 ant to promote the development of robust and sensitive assays of islet-reactive T-cells in patients w

196 ssayed by consensus sequencing and by a more sensitive assay (oligonucleotide ligation assay [OLA]) u

197 Here we present an inexpensive and sensitive assay platform for activity-based protease qua

198 essed in a label-free, quantifiable and very sensitive assay platform.

199 troponin detected by new-generation, highly sensitive assays predicts clinical outcomes among patien

200 Sensitive assay procedures were developed and employed t

201 We validated a highly specific and sensitive assay protocol that should be used as the stan

202 These robust and sensitive assays provide a toolkit for the identificatio

203 This rapid, simple, economical, and highly sensitive assay provides a practical alternative to dide

204 This simple and sensitive assay provides the basis for the development o

205 This sensitive assay quantifies specific bacteria in a sample

206 Thus, these new sensitive assays reveal a heretofore unappreciated, yet

207 INTERPRETATION: This new highly specific and sensitive assay showed asymptomatic infection with Ebola

208 Results of very sensitive assays showed that 6 of 31 monkeys had weak SI

209 HLA class I antibody development by a highly sensitive assay such as the PRA-STAT ELISA after LT can

210 iently applied in a reagent free manner, all sensitive assays such as these suffer, however, from pro

211 We examined this hypothesis using a highly sensitive assay system for detection of misfolded protei

212 ovides, along with gene fusion approaches, a sensitive assay system for signal sequences that utilize

213 ocyte and its meiotic spindle will provide a sensitive assay system for the study of reproductive tox

214 This sensitive assay system will become a powerful tool to di

215 CR offers a relatively simple-to-perform and sensitive assay system.

216 pend on the development of more reliable and sensitive assay systems, possibly formatted for cytochem

217 However, more sensitive assay techniques are needed when compared to b

218 repeat blood donors using the sensitive/less sensitive assay testing strategy was 2.95 per 100000 per

219 ential of these techniques to provide a more sensitive assay than behavioral measures used alone.

220 We have developed a highly sensitive assay that accurately determines the number of

221 iated epitopes in class II MHC, we devised a sensitive assay that averted potential activation of B c

222 In this regard, a sensitive assay that can accurately and rapidly quantify

223 receptors and that the SPA was a simple and sensitive assay that could be readily adapted into a hig

224 Here we describe a sensitive assay that enables quantitative analysis of ga

225 We have developed a rapid and sensitive assay that enables quantitative immunodetectio

226 gen affinity of each oxidase, using a highly sensitive assay that exploits globin deoxygenation durin

227 ied by measuring phalloidin binding sites, a sensitive assay that had not been used previously for pl

228 A sensitive assay that is capable of detecting the interac

229 This experimental system is a very sensitive assay that lends itself to the dissection of p

230 Utilizing a new sensitive assay that measures the production of glucosam

231 Development of a sensitive assay that measures the rate of cellular inter

232 Second, a sensitive assay that quantitates UTP mass at low nanomol

233 have therefore focused on the development of sensitive assays that allow the specific detection of si

234 dialysis and by steady-state kinetics using sensitive assays that allowed initial rate calculations.

235 yed in this quantitation platform for highly sensitive assays that can detect as low as 16 pM Ebola V

236 European small ruminant populations, highly sensitive assays that can specifically detect BSE, even

237 etter investigate this process, we developed sensitive assays that use the fluorescein arsenical dye

238 We measured cTnI using a sensitive assay (TnI-Ultra, Siemens Healthcare Diagnosti

239 Using this highly sensitive assay to analyze CHIKV nsP1 functionality, sev

240 Here we describe an extremely sensitive assay to analyze the effects of mutations on t

241 We developed an efficient and sensitive assay to compare active PKA levels based on bi

242 is, via clonogenic assay, was used as a more sensitive assay to confirm the interaction of the treatm

243 To accomplish this, a specific and sensitive assay to detect and serotype rhinovirus direct

244 We developed a rapid and sensitive assay to detect B. anthracis bacteremia using

245 ivity of PBP4, we developed a simple, highly sensitive assay to detect cellular pools of lipid-linked

246 We established a highly sensitive assay to determine frequencies of various cate

247 stepwise transcription approach and a highly sensitive assay to determine the dynamics of interaction

248 uated in susceptible strains, we developed a sensitive assay to directly quantitate sPLA2 activity in

249 D system with our previously reported highly sensitive assay to measure cre activity in vitro using a

250 It is very challenging to develop a highly sensitive assay to measure endogenous OT, including radi

251 Lack of a sensitive assay to measure MYDGF in the circulation has

252 ld further reduce this risk to <10%, using a sensitive assay to measure resistance.

253 We further report a new, highly sensitive assay to measure the activity of SepCysS under

254 Here, we describe a quantitative and sensitive assay to measure the ongoing activity of APOBE

255 Using a sensitive assay to measure the RAG1 activity level of 79

256 We have designed a novel, precise, and sensitive assay to measure unspliced (US) human immunode

257 ng and after radiotherapy that may provide a sensitive assay to monitor changes in radiation-induced

258 Here, we present a simple and sensitive assay to monitor mycoplasma contamination (myc

259 Here, we use a new, highly sensitive assay to redefine the relationship between mit

260 e application and further refinement of this sensitive assay to the replication of a T x T-containing

261 We use this sensitive assay to validate the activity of transcriptio

262 g observations and the recent development of sensitive assays to assess the in vivo levels of active

263 t this type of cell could be used to develop sensitive assays to detect herpesviruses.

264 urge the need for more rapid, accurate, and sensitive assays to detect potential allergens in food i

265 accine manufacturers are expected to develop sensitive assays to detect residual BSA.

266 one marrow aspiration and the lack of highly sensitive assays to detect residual disease present chal

267 electivity allowed us to apply our rapid and sensitive assays to detection of AA in vitamin C tablets

268 We have employed relatively simple and sensitive assays to determine the function of BRCA1 vari

269 evaluate this we used a complementary set of sensitive assays to explore the mtDNA rearrangements in

270 Sensitive assays to measure plasma and serum KIM-1 in mi

271 and in vivo, we have developed exceptionally sensitive assays to study the role of Escherichia coli t

272 A sensitive assay using biotinylated ubiquitin revealed ex

273 A sensitive assay using high-performance liquid chromatogr

274 r DNA than in plasma RNA, as determined by a sensitive assay using sufficient copies of virus, sugges

275 nsitivity in comparison to the previous most sensitive assay using the same mass spectrometry instrum

276 Sensitive assays using HLA class II multimers were used

277 interval [CI], 22.7%-27.4%) with the highly sensitive assay vs 0.7% (95% CI, 0.3%-1.1%) with the sta

278 cTnT detectable with a highly sensitive assay was associated with incident CHD, mortal

279 troponin T (cTnT) measured with a new highly sensitive assay was associated with incident coronary he

280 on-based cohort, cTnT detected with a highly sensitive assay was associated with structural heart dis

281 A more sensitive assay was therefore developed using multiple r

282 A highly sensitive assay was used to test the hypothesis that B c

283 In contrast, cTnI, measured using 2 sensitive assays, was persistently normal throughout the

284 Here we show, using a sensitive assay we developed, that the reduction of foli

285 id-induced microtubule depolymerization as a sensitive assay, we examined the characteristics of COC

286 Using a sensitive assay, we observed low levels of an unknown su

287 As a more sensitive assay, we used oligonucleotide microarrays to

288 Using sensitive assays, we found significant increases of hepa

289 Using highly sensitive assays, we have shown that B cell depletion is

290 hanges in cTnT levels measured with a highly sensitive assay were significantly associated with incid

291 We found that the most sensitive assays were those that used the E-gene primer-

292 D. magna was shown to be the most sensitive assay when carbon nanomaterials were present.

293 zation scheme could be easily adapted into a sensitive assay, where competition between tracer and ta

294 In particular, the need for a more sensitive assay will be emphasized.

295 during the "window period." Thus, the highly sensitive assay will be useful for early detection of HI

296 We believe that this inexpensive, rapid, and sensitive assay will find high relevance as an alternati

297 Such sensitive assays will facilitate distinguishing the rela

298 The development of more specific and sensitive assays will further illuminate the biology beh

299 solution melt (HRM) real-time PCR which is a sensitive assay with a rapid time-to-answer.

300 A simple and highly sensitive assay with optical amplification that uses the