ライフサイエンスコーパス: sensitization

1 cific case history supported by relevant IgE sensitization.

2 skin transepidermal water loss and allergic sensitization.

3 ed reflexes and group III/IV muscle afferent sensitization.

4 points and also with the risks of eczema and sensitization.

5 iota was not generally associated with later sensitization.

6 pollen exposure, leading to the peach nsLTP sensitization.

7 act directly on nociceptors to produce pain sensitization.

8 the dorsal root ganglion (DRG) to cause pain sensitization.

9 s with current asthma, hay fever, and pollen sensitization.

10 nd loss of GC dark zone B cells after peanut sensitization.

11 opus oryzae, an indoor mold causing allergic sensitization.

12 and means and thoroughness of assessment of sensitization.

13 ad to increased clinically relevant allergic sensitization.

14 portant especially in patients with allergic sensitization.

15 rgen exposure on the development of allergic sensitization.

16 ced by epicutaneous allergen ovalbumin (OVA) sensitization.

17 alcium, and calcineurin to initiate allergic sensitization.

18 indicating a centrally mediated component of sensitization.

19 that B cells contribute to indirect pathway sensitization.

20 associated with the early onset of allergic sensitization.

21 s of research into the mechanism of allergic sensitization.

22 allergen penetration predisposes to allergic sensitization.

23 4 and STAT6 signaling in the lungs after OVA sensitization.

24 nflammatory microglia activation and central sensitization.

25 when BMDCs were treated with GSK J4 prior to sensitization.

26 sociated with increased odds of milk and egg sensitization.

27 obial composition and seemed to protect from sensitization.

28 at 12 months were the main pathway to atopic sensitization.

29 ere was evidence for protection against food sensitization.

30 ion, with consequent increases in nociceptor sensitization.

31 e Th2 priming effect of CysLT1R signaling at sensitization.

32 istory of atopy, eczema, and house dust mite sensitization.

33 produces psychomotor, incentive, and neural sensitization.

34 -reactivity, which explains this observed co-sensitization.

35 e used for diagnosis of genuine poultry meat sensitization.

36 dritic spine density, leading to nociceptive sensitization.

37 loimmune response as represented by anti-HLA sensitization.

38 roaches for reversing peripheral nociceptive sensitization.

39 ine exposure caused long-lasting psychomotor sensitization.

40 crobial perturbations preceding early atopic sensitization.

41 luated in a murine model of Phl p 5 allergic sensitization.

42 and Tr1 responses upon epicutaneous protein sensitization.

43 9[31%] of 127 vs 45[29%] of 154), and atopic sensitization (14[13%] of 106 vs 13[11%] of 123) were si

44 tis (AD), allergic rhinitis (AR), asthma and sensitization against aeroallergens.

45 nd at the time of later biosampling with IgE sensitization against common food and inhalant allergens

46 We aimed to estimate the frequency of FA and sensitization against food allergens in primary school c

47 Prior sensitization against HLA class II antigens is associate

48 by current asthma, current hay fever, pollen sensitization, age, and other environmental factors.

49 ngs contribute to our understanding of cross-sensitization among different invertebrates and design o

50 ponents (component clusters) and patterns of sensitization among participants (sensitization clusters

51 r variables (Pru p 3 sensitization, Tri a 19 sensitization, anaphylaxis, and any NSAID different from

52 an children/adolescents with peanut/tree nut sensitization and a cohort of sensitized, high-risk, pre

53 el of house dust mite (HDM)-induced allergic sensitization and allergic airway inflammation.

54 Understanding the discrepancy between IgE sensitization and allergic reactions to peanut could fac

55 However, such treatment might itself induce sensitization and allergies, thus requiring hypoallergen

56 y treatments with holoBLG prevented allergic sensitization and anaphylaxis, while sustaining regulato

57 pment of atopic dermatitis; data on allergic sensitization and asthma were collected when children we

58 Furthermore, sensitization and challenge of mIgE-ITT-mutant mice with

59 e 2 cytokine production in a model of airway sensitization and challenge using a complete allergen th

60 e lungs of adult mice was observed following sensitization and challenge.

61 at combines a quantitative measure of T cell sensitization and clinical covariates.

62 teractions that are associated with allergic sensitization and clinical food allergy in the first yea

63 responses to cocaine, including psychomotor sensitization and cocaine self-administration.

64 caine-induced behaviors, including locomotor sensitization and conditioned place preference.

65 as, contributes to cocaine-induced locomotor sensitization and conditioned place preference.

66 mune states that predispose towards allergic sensitization and disease development remain ill defined

67 d behavioral adaptation, including locomotor sensitization and drug preference in rodents.

68 as been epigenetic mechanisms of psychomotor sensitization and drug reinforcement, as assessed by the

69 ic march and immune mechanism underlying the sensitization and effector phase of food allergy.

70 mus) can be controlled by host differential sensitization and energy transfer between lanthanide ion

71 ne whether microglia were critical to stress sensitization and exhibited increased reactivity to subs

72 ata that support the concept of epicutaneous sensitization and how this forms one half of the dual-al

73 of obesity triggers a high degree of leptin sensitization and improved leptin action, both centrally

74 ale-selective role of PRL/PRLR in nociceptor sensitization and in pathological pain conditions, inclu

75 This correlated with primary muscle afferent sensitization and increased expression of glial cell lin

76 PAG1 deficiency predisposed toward allergic sensitization and increased the severity of experimental

77 of an epithelial barrier defect on allergic sensitization and mast cell (MC) degranulation remains s

78 nel complexes regulate diversity in neuronal sensitization and may provide a therapeutic target for m

79 Given links between locomotor sensitization and mesolimbic dopamine signaling, we used

80 LR) in primary afferents promotes nociceptor sensitization and pain in a female-selective fashion.

81 To identify grass pollen sensitization and predict later ARg, allergen molecules

82 function and counteracts neuronal mechanical sensitization and reveal a key region for channel inhibi

83 This could provide clues regarding sensitization and severity patterns that might be releva

84 g axis in coordinating peripheral and spinal sensitization and shows that targeting Wnt5a-Ryk/ROR2 si

85 e 2 airway inflammation following peripheral sensitization and subsequent airway challenge with OVA.

86 ntion in this pathway could prevent allergen sensitization and subsequent Th2 allergic inflammation.

87 plex and include both peripheral and central sensitization and the involvement of the autonomic nervo

88 ant allergens increases the risk of specific sensitization and whether FLG mutations modulate these o

89 In two human cohorts, we link fungal sensitization and/or asthma with SNP/protein expression

90 ta), central factors (psychological aspects, sensitization and/or differences in connectivity or acti

91 investigated the association between fungal sensitization and/or positive fungal sputum culture and

92 ted pain increases when harm risks are high (sensitization) and decreases in the absence of such risk

93 s transepithelial allergen passage, allergic sensitization, and allergen-induced MC degranulation eve

94 h development of atopic dermatitis, allergic sensitization, and asthma.

95 itosan-induced barrier dysfunction, allergic sensitization, and MC degranulation.

96 , protected mice from passive and active IgE sensitization, and resulted in cross-protection against

97 Epicutaneous sensitization- and bone marrow reconstitution-based mode

98 -cell numbers in children with food-allergic sensitization are suggestive of TGF-beta-mediated compen

99 g surgery, preventing the chronic nociceptor sensitization associated with such injuries, led to even

100 opic dermatitis, inhalant- and food-allergic sensitization, asthma lung function scores was obtained

101 hs: NS 19%, ST 32%, FA 64%; and aeroallergen sensitization at 4 years: NS 19.1%, ST 28.6%, FA 44.4%.

102 EV(1) , FVC), higher FeNO and higher risk of sensitization at 8 years.

103 rent asthma, allergic rhinitis, and allergen sensitization at a median age of 12.9 years.

104 assessed for food allergen and aeroallergen sensitization, atopic dermatitis, allergic rhinitis, ast

105 -deficient B cells into muMT mice before HDM-sensitization attenuated AHR and lung remodeling.

106 ons of complex trauma, including nociceptive sensitization, bone fracture, muscle fibrosis and muscle

107 After HDM-sensitization, both wild-type and muMT mice developed AH

108 e relationship between allergen exposure and sensitization, but effects differ at different ages and

109 between children with or without IgE-related sensitization, but only in Finland.

110 mice and rat neurons and counteracts PIEZO2 sensitization by bradykinin.

111 e; and (b) the possibility of recipient allo-sensitization by CMV-mediated disruption of stable toler

112 st nociceptor population-specific changes in sensitization by prostaglandin E(2) (PGE(2)) were observ

113 Both mutations showed pro-apoptotic sensitization by reduced phosphorylation of BAD.

114 d tolerance disruption led to recipient allo-sensitization by reverting the tolerant state of allo-sp

115 elucidated the RIPK1-dependent mechanism of sensitization by SMAC mimetics.

116 gical mechanisms involved in peanut allergen sensitization by using mouse models.

117 advantageous marine mollusk Aplysia, LTM for sensitization can be induced by the presentation of two

118 nged by the observation [2] that nociceptive sensitization caused by a chronic pain-producing injury

119 Locomotor sensitization caused by interrupted morphine exposure wa

120 Four sensitization clusters were identified, but with no diff

121 atterns of sensitization among participants (sensitization clusters).

122 Both passive and active prenatal sensitization conferred allergen sensitivity, resulting

123 Patients with peach allergy due to nsLTP sensitization constitute a heterogeneous group in terms

124 Additionally, nicotine locomotor sensitization correlated with accumbal dopamine modulati

125 Profilin sensitization could be more useful as a severity biomark

126 We obtained sensitization data and/or sputum from 175 children: 99 w

127 threshold, memory of prior injury, and pain sensitization/desensitization.

128 gE reporter cells, creating a novel allergic sensitization detection system.

129 Despite known M. tuberculosis sensitization determined by interferon-gamma release ass

130 stingly, IL-4Ralpha knockdown after allergic sensitization did not induce T(H) 17, a neutrophilic inf

131 y and attenuates the expression of locomotor sensitization, directly linking OFC-DMS potentiation to

132 associated with the development of allergic sensitization, eczema, or asthma.

133 posure reduces the rewarding and psychomotor sensitization effects of cocaine.

134 The observed strong dependence of (1)O(2) sensitization efficiency on SWCNT structure suggests tha

135 hew, hazelnut, pistachio, walnut) allergy or sensitization from Canadian (n = 150) and Austrian (n =

136 pic dermatitis, inhalant-, and food-allergic sensitization had higher memory Treg cell numbers 12.3%

137 Children with food-allergic sensitization had higher total B and CD27(+) IgA(+) memo

138 eem to increase the overall risk of allergic sensitization; however, sensitization to birch as well a

139 Next, we applied the sensitization hypothesis to our model, which predicts th

140 previous predator experience, supporting the sensitization hypothesis.

141 ohort of pregnant women patterns of allergic sensitization in adulthood were not found to differ betw

142 istration of recombinant IFNgamma during HDM sensitization in C57Bl/6 mice blocked Th2 development.

143 in mechanistic understanding of nociceptive sensitization in chronic pain with a focus on neuroimmun

144 aling), which is known to produce nociceptor sensitization in inflammatory and neuropathic pain condi

145 During Phl p 5 sensitization in mice, TGFbeta1-mim downregulated IL-2,

146 ereotypies and anxiety and blunted locomotor sensitization in morphine abstinent mice.

147 therefore supports close monitoring for allo-sensitization in previously tolerant transplant recipien

148 ity to more than one nut is frequent, and co-sensitization in the absence of clinical data is often o

149 the incidence of allergic diseases or atopic sensitization in the first 2 years of life in children b

150 utcomes; however, they can contribute to HLA sensitization in the recipients.

151 .Z cKO also has sex-specific effects on fear sensitization in the stress-enhanced fear learning (SEFL

152 According to sustained sensitization in tiers 1 and 2, T cell-related signaling

153 ight hyaluronan (HMWH) attenuates nociceptor sensitization, in the setting of inflammation.

154 ng function compared with asthmatics without sensitization including a lower FEV(1) /FVC ratio (p < .

155 pplement for those AD patients with allergic sensitization interferes with IgE-mediated inflammatory

156 d tolerance and on subsequent recipient allo-sensitization is a clinically important unanswered quest

157 Fungal sensitization is a feature of children with chronic asth

158 Allergic sensitization is associated with severe asthma, but asse

159 ure air to pollution has effects on allergic sensitization is controversial.

160 Differential sensitization is influenced by distinct expression of in

161 Recent studies show that nsLTP sensitization is not limited to the Mediterranean basin

162 ciated with severe asthma, but assessment of sensitization is not recommended by most guidelines.

163 ng that early diagnosis of donor-derived IgE sensitization is possible.

164 Neither of these types of pain sensitization is well understood.

165 Early sensitization is ~50% higher in children with atopic der

166 By contrast, in the model with OVA sensitization, LCs inhibited T(FH)/GC response and suppr

167 ased on their treatment (Active/Placebo) and sensitization level (Mono/Poly).

168 Based on their sensitization level, 22 patients were allocated in Mono-

169 dividuals with asthma, hay fever, and pollen sensitization may be at higher risk.

170 tained unresponsiveness and prevents further sensitization mediated by Tregs.

171 ment, cytochrome P450 3A5 genotype, pregraft sensitization, mo 3 glomerular filtration rate).

172 An epicutaneous sensitization model was used and bone marrow reconstitut

173 In a passive sensitization model, mice were injected with IgE to Derm

174 on TSLP in both the MC903 model and the OVA sensitization model.

175 in an epicutaneous protein (ovalbumin, Ova) sensitization model.

176 reas these cells remained inactivated in OVA sensitization model.

177 Congruent with stress sensitization models of MDD, with each consecutive MDE i

178 was not predicted by traditional markers of sensitization, nor did it appear to be related to measur

179 Sensitization occurred in 46.5% (66/142) of participants

180 xposure of the acene to light, often through sensitization of (1)O(2), is an important reaction requi

181 tic experiments revealed that triplet energy sensitization of a Cu-bound radical precursor facilitate

182 tization in periaqueductal gray, nor a super-sensitization of adenylyl cyclase in the striatum, which

183 erase 1 (TDP1) is a molecular target for the sensitization of cancer cells to the FDA-approved topois

184 3.1 channels caused a modest but significant sensitization of cancer cells to the growth suppressant

185 take and seek cocaine was also reduced, and sensitization of cocaine's actions at the DAT was revers

186 ups but not in healthy controls, arguing for sensitization of cutaneous mechano- and heat-sensitive C

187 kin response was dependent on the particular sensitization of each patient, obtaining an increased re

188 rovided a functionalizable interface for the sensitization of electrode probes; besides, a suitable h

189 found that H2A.Z cKO reduced stress-induced sensitization of fear learning and pain responses prefer

190 the impact of chronic opioid regimens on the sensitization of fear learning seen following traumatic

191 ing BODIPY localization and was validated by sensitization of mammalian cells and neurons by visible-

192 the trigeminal nucleus complex, and central sensitization of medullary dorsal horn neurons is a crit

193 Airway sensitization of naive mice with RSV-infected BMDCs exac

194 c acetylcholine receptors in the generalized sensitization of nociceptive responses in caterpillars.

195 nervous system, which may contribute to the sensitization of nociceptors by cytokines in pain develo

196 ated that protons exert their effect through sensitization of PLCdelta1 to Ca(2+) , which in turn pro

197 l adaptations ultimately leading to enhanced sensitization of reward circuitries towards food reward.

198 ved to be the most critical for differential sensitization of sensory neurons.

199 of cognitive effort involves dACC-initiated sensitization of task-relevant areas.SIGNIFICANCE STATEM

200 pplication of HMWH attenuated PGE(2)-induced sensitization of tetrodotoxin-resistant sodium current,

201 herapy, as well as DFMO-induced preferential sensitization of TNBC cells to chemotherapy, reported he

202 inst these domains substantially reduced the sensitization of TRPA1, as well as BK- and CFA-induced h

203 ysiology is due in part to subtype-dependent sensitization of TRPV1 and TRPA1.

204 /-) B cells into muMT(-/-) mice a day before sensitization or a day before challenge.

205 nd children with inhalant- and food-allergic sensitization or atopic dermatitis had higher circulatin

206 arker than the number of nsLTP, aeroallergen sensitizations or sIgE levels.

207 e was associated with a reduced risk of food sensitization (OR at 12 years, 0.08; 95% CI, 0.01-0.67).

208 ignificantly higher risk developing allergic sensitization(OR [95% CI] = 2.00 [1.04:3.86] at age 4; 2

209 was less frequent in patients with profilin sensitization (P = .03).

210 However, sensitization patterns of Taiwanese patients to crustace

211 ionally been confined to the initial antigen sensitization phase.

212 LIT, as well as the influence of the patient sensitization phenotype (Mono- or Poly-sensitized).

213 wever, a test that indicates there is peanut sensitization present (eg, a "positive" test) is not alw

214 This co-sensitization process would occur because of the cross-r

215 co-administration suppressed the psychomotor sensitization produced by IntA cocaine experience.

216 was to analyse the clinical characteristics, sensitization profile and severity of reactions in peach

217 constitute a heterogeneous group in terms of sensitization profile and severity.

218 ents with HDM allergy according to molecular sensitization profiles and molecular monitoring of AIT-i

219 fferent extents depending on their molecular sensitization profiles.

220 the prescription of SLIT, based on specific sensitization profiles.

221 allergy screening campaigns to better define sensitization profiles.

222 persible budesonide tablet revealed a strong sensitization, proving a T cell mediated allergy to bude

223 i-IgE autoantibodies prevented effector cell sensitization, reduced total IgE serum levels, protected

224 Furthermore, the sensitization-regulated nociceptors (SRN) can greatly as

225 e whether traditional markers of Aspergillus sensitization related to the presence of Aspergillus wit

226 amine might reduce cocaine use by preventing sensitization-related changes in cocaine potency at the

227 the observed differences for later allergic sensitization remains open.

228 ic pain state and its associated nociceptive sensitization represented an adaptive function.

229 PLA(2)s play an important role in peripheral sensitization, resulting in airway responses to inhaled

230 AD may increase sensitization risk over heredity alone.

231 heir strengths and limitations for assessing sensitization risks.

232 Indeed, the term severe asthma with fungal sensitization (SAFS) has been coined.

233 mL) can identify clinically relevant Mal d 3 sensitization (sensitivity of 60%-63% and a specificity

234 Prevalence of food allergen sensitization (sIgE >= 0.35 kU(A) /L) varied by food: mi

235 he treatment of pain generated by nociceptor sensitization.SIGNIFICANCE STATEMENT High-molecular-weig

236 ng applications in energy up-conversion, dye sensitization, spintronics, photoredox catalysis, and or

237 ergenic food ingestion, food reaction(s) and sensitization status.

238 inistration produced psychomotor (locomotor) sensitization, strong motivation to take and seek cocain

239 olerance to Peanut study, and Peanut Allergy Sensitization study participants by administering the ba

240 pes indicating differential roles in insulin sensitization, suggesting mechanisms bridging the associ

241 e higher among participants without allergic sensitization than among those with, but interaction was

242 ulation revealed an additional site-specific sensitization that has not previously been described in

243 single B epitope, prevents IgE-mediated milk sensitization through the induction of Th1-mediated immu

244 vidence regarding the importance of allergic sensitization through the skin.

245 patients with rhinoconjunctivitis caused by sensitization to A alternata.

246 F1R signaling pathway effectively suppresses sensitization to aeroallergens and consequent allergic l

247 to 16 (n = 5825) years were analyzed for IgE sensitization to allergen extracts by ImmunoCAP.

248 pithelial barrier play a crucial role in the sensitization to allergens and pathogenesis of asthma.

249 Assessing immunoglobulin E (IgE) sensitization to allergens is an important strategy for

250 y immunodeficiency disorders associated with sensitization to allergens.

251 who are at high immunologic risk because of sensitization to alloantigens, including those who have

252 tween FLG and dog ownership, but the risk of sensitization to any allergen was significantly lower am

253 ion was not consistently associated with IgE sensitization to any common allergen extract up to age 1

254 The prevalence of sensitization to any Phl p molecule was higher compared

255 ecific analyses suggested increased risks of sensitization to birch (odds ratio [OR] = 1.12 [95% CI =

256 all risk of allergic sensitization; however, sensitization to birch as well as grass pollen Phl p 1 a

257 Six weeks after sensitization to bovine casein, mice received four, mont

258 ading to accumulation of RIPK3 and CASP8 and sensitization to cell death.

259 We used a model of house dust mite sensitization to challenge wild-type, Bcl6(fl/fl) Foxp3-

260 Src signaling, induction of apoptosis and re-sensitization to chemotherapy.

261 t) rats, preexposure to WIN results in cross-sensitization to cocaine, which correlates with histone

262 Overall, IgE sensitization to extracts was highly prevalent (43%-73%)

263 a-1,3-fucose) was positively associated with sensitization to extracts, rural environment and Sm infe

264 ty and may increase the risk of epicutaneous sensitization to food allergens.

265 and outcomes of infants who demonstrate IgE sensitization to foods that they clinically tolerate.

266 modulate the immune response during allergic sensitization to grass pollen allergens.

267 st act as environmental adjuvants to promote sensitization to inhaled peanut in mice.

268 fic for almond allergy, while frequencies of sensitization to legumins from peanut, walnut, hazelnut,

269 ousehold endotoxin level was associated with sensitization to milk (OR 1.7, 95% CI 1.2-2.1) and egg (

270 h high doses of nCyp c 1 or mCyp c 1, before sensitization to nCyp c 1.

271 he same regions are also important for viral sensitization to neutralizing antibodies, directly linki

272 RUM with data from HCB showed differences in sensitization to olive tree pollen and profilin (P = .01

273 Sensitization to PR-10 or profilin, IgE to Bet v 1 and/o

274 Therefore, sensitization to profilin seems to be a marker of severi

275 Sensitization to Pru du 6 was highly specific for almond

276 acotherapy for individuals with symptoms and sensitization to specific allergens.

277 ssociations between house dust endotoxin and sensitization to specific foods (milk, egg, and peanut).

278 any Ole e 7-sensitized patients exhibit a co-sensitization to the peach nsLTP, Pru p 3.

279 but not with skin reactivity to extracts or sensitization to their major allergenic components.

280 Sensitization to thermotolerant fungi, including filamen

281 Using just four variables (Pru p 3 sensitization, Tri a 19 sensitization, anaphylaxis, and

282 ncy at the DAT, consistent with an incentive-sensitization view of addiction.

283 Sensitization was assessed at 6 time points between infa

284 The predisposition to allergic sensitization was associated with increased airway epith

285 Active sensitization was attempted by repeated intranasal ovalb

286 Sensitization was determined using serum-specific IgE an

287 Sensitization was differentially targeted between popula

288 connection between tick bites and alpha-Gal sensitization was further supported by patients' respons

289 from rats with OIHP, enhanced PGE(2)-induced sensitization was observed in vitro, with differences id

290 atopic eczema, food allergy, wheeze, atopic sensitization) was assessed in a subgroup of ProPrems in

291 e impact of immunosuppressive therapy on IgE sensitization, we prospectively studied 5 atopic living-

292 transepidermal water loss and allergic sensitization were assessed.

293 nalyses, the risk of asthma and aeroallergen sensitization were increased in urban infants.

294 tails of allergic disease outcomes including sensitization, wheeze, asthma, and eczema were collected

295 s through which type I IFNs cause nociceptor sensitization with implications for understanding how vi

296 The increase in risk of mite sensitization with increasing Der p 1 exposure was consi

297 Variable patterns of sensitization with no immunodominant allergens were foun

298 tion between FLG and Fel d 1 exposure on cat sensitization, with the effect of exposure being signifi

299 88 knockout mice, morphine-induced locomotor sensitization, withdrawal and supra-spinal analgesia wer

300 ation of IL-4Ralpha signaling after allergic sensitization would have significant therapeutic benefit