ライフサイエンスコーパス: septation

1 etic role in fungal cell wall biogenesis and septation.

2 the endocardium is required for ventricular septation.

3 the cardiac valves and for complete cardiac septation.

4 ts of daptomycin on cell wall morphology and septation.

5 CAR) and remains at the division site during septation.

6 be a SHF Tbx5-Hh network required for atrial septation.

7 displayed more defective growth and aberrant septation.

8 urin complex in regulating hyphal growth and septation.

9 d with claudins in epithelia at the point of septation.

10 e digested, allowing Bdellovibrio growth and septation.

11 of large axial filaments that interfere with septation.

12 rated by FtsZ, which forms a Z-ring to drive septation.

13 region, which segregates immediately before septation.

14 ure of cardiac outflow tract and ventricular septation.

15 gle mispatterned ventricular chamber lacking septation.

16 morphogenesis, indicating a primary role for septation.

17 ed for vegetative growth but only for timely septation.

18 entity, indicating a requirement for Tbx5 in septation.

19 equired in the pulmonary endoderm for atrial septation.

20 y also results in the failure of cardiac OFT septation.

21 eing synthesized and rapidly degraded during septation.

22 ly synthesized septal PG was degraded during septation.

23 substantial contribution to atrioventricular septation.

24 ze PG degradation during cell elongation and septation.

25 hymal structure involved in atrioventricular septation.

26 in cushion/valve remodeling and ventricular septation.

27 th other than those strictly associated with septation.

28 us region, leading to defects in aortic arch septation.

29 es, all of which are required for normal OFT septation.

30 (CNCCs), are crucial for OFT development and septation.

31 g migration, leading to a failure of the OFT septation.

32 entral and dorsal outflow cushions before AP septation.

33 pharyngeal endoderm regulates outflow tract septation.

34 n mother cell and prespore immediately after septation.

35 mental control of chromosome replication and septation.

36 stations of MFS, including impaired alveolar septation.

37 ring, and plays an essential role in fungal septation.

38 gnaling plays a non-autonomous role in digit septation.

39 ation-associated chromosome condensation and septation.

40 que perineal structures derived from cloacal septation.

41 bstantial levels in mutants blocked in polar septation.

42 chial-arch arteries (BAAs) and defective OFT septation.

43 present a fully penetrant failure in cloacal septation.

44 roliferation, and lack of proper ventricular septation.

45 pression pattern and its depletion perturbed septation.

46 tion related to structures formed by cloacal septation.

47 phenotypic abnormalities, including cardiac septation.

48 networking and downstream targets for atrial septation.

49 1 in the second heart field (SHF) for atrial septation.

50 have contributed to the evolution of cardiac septation.

51 tin landscape of endocardial lineages during septation.

52 , simultaneous with the evolution of cardiac septation.

53 d cell migration genes that are critical for septation.

54 ntial for outflow tract and atrioventricular septation.

55 wth poles of both siblings immediately after septation.

56 a small subset of mitotic genes involved in septation.

57 he actomyosin ring, and thus promotes medial septation.

58 ricular, outflow tract and aortico-pulmonary septation.

59 dinating their expression during sporulation septation.

60 cardial thickness at E11.5, prior to cardiac septation.

61 division site and may mark previous sites of septation.

62 to ensure DNA is properly segregated before septation.

63 localization in the longest cells undergoing septation.

64 , and cell division by sequential orthogonal septations.

65 loating echoes and thin, incomplete internal septations.

66 %; 95% confidence interval [CI]: 20, 30) had septations.

67 sion without any solid components, debris or septations.

68 velopment: (1) outflow tract development and septation, (2) tissue remodeling events required for car

69 , or with a nodule or multiple thin or thick septations (60%-100%).

70 Loculations (84.2 %) and septations (63.2 %) were the most common radiologic find

71 morrhagic (59%) and those with a single thin septation (67%); 31% of cysts measuring 1-7 cm in postme

72 ortened cardiac outflow tract with defective septation, a process known to require neural crest cells

73 efects, characterized by disrupted secondary septation, abnormal alveolar epithelial cell differentia

74 An unanswered question is how polar septation activates a transcription factor (sigma(F)) se

75 rdial cells derived from the AHF to complete septation after cushion formation.

76 Mig-6(-/-) lungs (E15.5-P3) revealed reduced septation, airway over-branching, alveolar type II cell

77 mbly and sometimes even ring contraction and septation, all during interphase.

78 near heart tube, through complex looping and septation, all the while increasing in mass to provide t

79 heory that as alveoli form through secondary septation, alveolar flow becomes chaotic and chaotic mix

80 hich specifically corresponds to the primary septation/alveolarization phase of lung development.

81 Later, during septation and abscission, a second GEF-independent mecha

82 th clearing chromosomal DNA from the site of septation and also acts to position the dif sites for re

83 deficiency results in both impaired alveolar septation and altered morphology of the pulmonary neuroe

84 letion mutant exhibits irregular sporulation septation and altered spore shape, suggesting that SspA

85 Thus, it is possible that ventricular septation and appropriate outflow tract alignment is dep

86 e essential functions of alpha(1-3)glucan in septation and cell separation.

87 hB receptors impairs morphogenetic cell-cell septation and closure events during development of the e

88 egative regulators of the SIN suppressed the septation and conidiation phenotypes due to the loss of

89 The MOBA protein was required for septation and conidiation, but was not essential for hyp

90 ated with the SPB and is required for timely septation and conidiation.

91 eraction against the SIN pathway to regulate septation and conidiation.

92 rdiac morphogenesis, including outflow tract septation and cushion defects, a thin ventricular myocar

93 IcsA localization is independent of the cell septation and cytokinesis proteins FtsQ and FtsEX.

94 ay a central role in regulating the onset of septation and cytokinesis.

95 roliferation, correlating with inhibition of septation and developmental emphysema.

96 tion of new cell wall deposition during cell septation and elongation.

97 urs, which had nuclear pleomorphism, fibrous septation and increased galectin-3 expression, consisten

98 orulation, plasmid segregation occurs before septation and independently of the DNA translocase SpoII

99 cushions is essential for proper ventricular septation and morphogenesis of the mature mitral and tri

100 F) are required for OFT and atrioventricular septation and OFT alignment.

101 rotein, yielded cells with strong defects in septation and polarity respectively.

102 t interact with TBX20 to orchestrate cardiac septation and provides insight into the chromatin landsc

103 s, epithelial cell differentiation, alveolar septation and regulation of alveolar homeostasis.

104 s to the contractile actin ring early during septation and remains at the centre of the mature septum

105 c and neonatal lungs, their role in alveolar septation and the therapeutic potential of these cells r

106 tilaginous structures, cardiac outflow tract septation and thymic and dorsal root ganglia development

107 SftA and SpoIIIE act at different stages of septation and together they ensure maximum fidelity in c

108 V) junction plays a critical role in chamber septation and transmission of cardiac conduction pulses.

109 Internal septations and loculations on radiologic examinations sh

110 that triggers actomyosin ring constriction, septation, and cell division.

111 (SIN) triggers actomyosin ring constriction, septation, and cell division.

112 ins at a very early stage, culminates during septation, and decays after division is completed.

113 itylation results in defects in cell growth, septation, and nuclear structure, phenotypes not observe

114 these sites is independent of FtsZ, MinCDE, septation, and nucleoid occlusion, indicating that posit

115 on, outflow tract (OFT) and atrioventricular septation, and OFT alignment.

116 ivision septum, promoting ring constriction, septation, and subsequent cell separation following ring

117 Cyst features, including location, septations, and mural nodules and multiplicity, were not

118 ity, presence of rim enhancement or internal septations, and the shape of the contrast material kinet

119 f Gram-negative bacteria is recruited to the septation apparatus during cell division where it is inv

120 g is identified in tracheoesophageal foregut septation, as animals lacking the cytoplasmic domain of

121 tablish that Pom1's kinase activity prevents septation at cell tips even if Mid1 is absent or misloca

122 Age, cyst size, and cyst septation at presentation were not predictive of growth.

123 and ring contraction occurs concomitant with septation at the end of anaphase.

124 After septation, Bdellovibrio flagellar motility resumes insid

125 clin-dependent kinase (CDK) and the onset of septation, before G1-CDK can be reactivated and drive re

126 he RA receptor-deficient background restores septation but does not rescue alignment defects, indicat

127 TA4 and TBX5 is important for normal cardiac septation, but the underlying molecular mechanisms are n

128 th muscle from the secondary heart field and septation by cardiac neural crest cells.

129 Regulation of septation by PhoQ/PhoP may protect cells from antimicrob

130 Shh directs cloacal septation by promoting cell proliferation in adjacent ur

131 ise), and FCPL-specific (ie, size, location, septation, calcification, mural nodularity, pancreatic d

132 activity, which could arise from asymmetric septation, can achieve the all-or-nothing response in si

133 orphogenesis, with special emphasis on polar septation, chromosome translocation, and the phagocytosi

134 Both myoB and myoE are necessary for proper septation, conidiation, and conidial germination, but on

135 mutants, exhibited defects in cell shape and septation, consistent with the idea that the availabilit

136 ial growth in broth culture; however, normal septation could be restored if mutant cells were cocultu

137 ce despite the pronounced exponential growth septation defect.

138 result in potentially fatal atrioventricular septation defects (AVSD).

139 nd heart field (SHF) and heart outflow tract septation defects are combined, although the mechanistic

140 thogenic pathway when second heart field and septation defects are coupled.

141 ydrolase NamA and demonstrate that bacterial septation defects associated with a loss of NamA are fun

142 velopment results in outflow and ventricular septation defects commonly observed in congenital heart

143 shion morphology that preceded a spectrum of septation defects from double outlet right ventricle to

144 ion in the myocardium contributes to cardiac septation defects in humans.

145 after neural tube closure results in severe septation defects in the chick, reminiscent of human bir

146 xpression of active Rho4 or Eng1 rescues the septation defects of mutants containing gef3.

147 ced cell proliferation, and atrioventricular septation defects similar to Gata4;Tbx5 compound heteroz

148 es, leading to both outflow tract and atrial septation defects that can be rescued by an activated fo

149 enes secA2 mutants form rough colonies, have septation defects, are impaired for swarming motility, a

150 ephalic/carotid artery aneurysms and cardiac septation defects, but developed extensive and apparentl

151 resulted in interventricular septal chamber septation defects, suggesting that TGFbeta superfamily s

152 n Tbx5 and Mef2c, manifesting as ventricular septation defects, was validated in mice.

153 fects, indicating that excess TGFbeta causes septation defects.

154 ment into the OFT cushions, resulting in OFT septation defects.

155 bution of CnaA and CnaB to hyphal growth and septation, DeltacnaB and DeltacnaADeltacnaB strains of A

156 mbryos display significant rescue of cardiac septation, demonstrating that disruption of this Pbx1-Pa

157 genetic imbalance is unlikely to affect the septation-dependent release of sigmaF.

158 Thus, the position of oriC after septation determines which cell will receive the chromos

159 e in the context of the evolution of cardiac septation: do they possess a single ventricular chamber

160 itical role in ensuring appropriate alveolar septation during alveologenesis.

161 sL and DivIC are not absolutely required for septation during growth and sporulation.

162 e pharyngeal arch arteries and outflow tract septation during heart development, but the lineage spec

163 artery remodeling and cardiac outflow tract septation during vertebrate development.

164 lutamide-treated males does not undergo this septation event.

165 novel role for FtsK in linking cell envelope septation events and yields further evidence for FtsK as

166 E. coli is specifically induced by aberrant septation events caused by mis-oriented Z rings and not

167 enesis, after which it undergoes a series of septation events leading to the formation of the anal ca

168 ays originated from the remnants of abnormal septation events, cementing the relationship between abe

169 Later during aorticopulmonary septation, excessive proliferation in the OFT cushion me

170 Moreover, defects in cell septation, exocytosis, and endocytosis in sec3 mutant st

171 ausing severe OFT cushion hypoplasia and OFT septation failure.

172 ring that provides membrane tethering to the septation FtsZ protein, has been incorporated in single

173 ring that provides membrane tethering to the septation FtsZ protein.

174 e, placental labyrinth morphology, lung lobe septation, hair growth, and vascularization of kidney gl

175 contribution of extracardiac cells to atrial septation has recently been recognized.

176 is largely dispensable for ingression; once septation has started, cleavage can continue in the abse

177 utflow and inflow tracts, defects in cardiac septation, heart position, as well as abnormal ventricul

178 d in the Acvr1 locus only partially restored septation in Acvr1 mutants.

179 indicate that in addition to nucleating cell septation in E. coli, FtsZ can direct the insertion of n

180 s 511 and 521, is essential for normal lobar septation in early lung development and normal alveoliza

181 Septation in Fgcdc14 was reduced and hyphal compartments

182 x and activates Rho4 GTPase as a Rho GEF for septation in fission yeast.

183 d in the second heart field (SHF) for atrial septation in mice.

184 trol great-artery patterning and cardiac OFT septation in mice.

185 Mitotic exit in Saccharomyces cerevisiae and septation in Schizosaccharomyces pombe are regulated by

186 The septation in terminal alveoli of lungs in mgR mice was r

187 t has developmental emphysema with decreased septation in terminal alveoli.

188 ed conidiation was concomitant with restored septation in the absence of the MOBA protein.

189 Heart development before septation in the chick embryo was studied under two hype

190 ivation on both anaphase B SPBs and promotes septation, indicating that Fin1 restrains SIN activity o

191 monary outflow tract valvulogenesis, cardiac septation, inflow tract morphogenesis, as well as abnorm

192 The septation initiation network (SIN) and mitotic exit netw

193 a Hippo-related signaling pathway termed the septation initiation network (SIN) controls CR formation

194 In fission yeast, the septation initiation network (SIN) ensures temporal coor

195 ase complex is an important component of the septation initiation network (SIN) in the fission yeast

196 Strikingly, the Hippo-like septation initiation network (SIN) induces Cdr2 dissocia

197 The Schizosaccharomyces pombe septation initiation network (SIN) is an Spg1-GTPase-med

198 fission yeast Schizosaccharomyces pombe the septation initiation network (SIN) is required for stabi

199 ermed the mitotic exit network (MEN) and the septation initiation network (SIN) keeps Cdc14 and Clp1,

200 The septation initiation network (SIN) regulates the timing

201 The septation initiation network (SIN) serves to coordinate

202 The Schizosaccharomyces pombe septation initiation network (SIN) triggers actomyosin r

203 be, a late mitotic kinase pathway called the septation initiation network (SIN) triggers cytokinesis.

204 , Dma1, delays cytokinesis by inhibiting the septation initiation network (SIN) when chromosomes are

205 ents are coordinated with cytokinesis by the septation initiation network (SIN), an essential spindle

206 The septation initiation network (SIN), analogous to the Hip

207 depends on Sid4 and Cdc11, components of the septation initiation network (SIN), but not on other SIN

208 The kinase cascade of the septation initiation network (SIN), first revealed in fi

209 . cerevisiae and its homologous network, the septation initiation network (SIN), in S. pombe act thro

210 s, cytokinesis/septation is triggered by the septation initiation network (SIN), which first appears

211 (SPB) through a regulatory pathway named the septation initiation network (SIN).

212 change in Cdc15 mobility is dependent on the septation initiation network (SIN).

213 genetic interactions with two mutants of the septation initiation network pathway, a signaling cascad

214 rogression through anaphase, interferes with septation initiation network signaling, and additionally

215 dispersing into the cytoplasm, dependent on septation initiation network signaling.

216 he AnBud3-Rho4 module acts downstream of the septation initiation network to mediate recruitment of t

217 trations of Sid2p and Mob1p (proteins of the septation initiation network) and measured their binding

218 p and Mob1p, a protein kinase complex of the septation initiation network, and confirm known interact

219 cytokinesis and may negatively regulate the septation initiation network.

220 -cycle regulators such as polo kinase or the septation initiation network.

221 contractile-ring maintenance and affects the septation initiation network.

222 For example, the Schizosaccharomyces pombe septation-initiation network (SIN), which is responsible

223 Accordingly, defective OFT septation is a life-threatening condition that can occur

224 d upon septum completion but stabilized when septation is aberrant.

225 Overproduction of ZipA at levels that block septation is accompanied by the displacement of FtsZ and

226 dination of outer membrane constriction with septation is critical to faithful division in Gram-negat

227 Cardiac outflow tract (OFT) septation is crucial to the formation of the aortic and

228 ly circumscribed ribbon around midcell where septation is destined to take place.

229 Thus ventricular septation is established by a steep and correctly positi

230 Upon IcsA localization to these sites, septation is inhibited, suggesting that IcsA recognition

231 -EGFP knock-in mice, showed that ventricular septation is initiated at embryonic day 9 by the movemen

232 nism by which these proteins orchestrate OFT septation is not yet understood.

233 Although the importance of the DMP to AV septation is now established, the molecular and cellular

234 ous fungus Aspergillus nidulans, cytokinesis/septation is triggered by the septation initiation netwo

235 initiating actomyosin ring constriction and septation, is assembled at the SPB through its two scaff

236 iously unrecognized relationship between the septation machinery and ostensibly minor peptidoglycan-m

237 Epithelial remodelling during septation may cause loss of cell-cell or cell-matrix int

238 sis of the pulmonary airways and the cardiac septations necessary for pulmonary circulation.This arti

239 ha1LG3-5 completely rescued defects in digit septation, neural tube closure, placental labyrinth morp

240 In the mouse, septation occurs postnatally and is thought to require t

241 pite the requirement for NamA for the normal septation of exponentially growing L. monocytogenes cell

242 eart development, consisting of the improper septation of the cardiac outflow tract (OFT) and remodel

243 ent truncus arteriosus (PTA) is a failure of septation of the cardiac outflow tract (OFT) into the pu

244 indbrain rhombomeres 6-8) contributes to the septation of the cardiac outflow tract and the formation

245 Septation of the cloaca is a unique mammalian adaptation

246 h and patterning of the genital tubercle and septation of the cloaca, and a later external genital ph

247 er from respiratory outgrowth or progressive septation of the foregut tube.

248 Septation of the gas-exchange saccules of the morphologi

249 remodelling of the pharyngeal arches and the septation of the heart and outflow tract.

250 Defects in cardiac valve morphogenesis and septation of the heart chambers constitute some of the m

251 irds, mammals and crocodilians into complete septation of the heart into left and right sides, allowi

252 yme as required for valvular development and septation of the heart.

253 unconventional, multi-point and synchronous septation of the intracellular Bdellovibrio, accommodati

254 Septation of the mammalian heart into four chambers requ

255 ein and male lethality because of incomplete septation of the outflow tract of the heart, which produ

256 is involving their migration to the heart or septation of the outflow tract.

257 evelopment of the atrioventricular canal and septation of the outflow tract.

258 les, formation of the urethral tube involves septation of the urethral plate by continued growth of t

259 e proper alignment of the outflow tracts and septation of the ventricles are a highly significant cau

260 l heart defects involve anomalies in cardiac septation or valve development, and understanding the de

261 not associated with presence of radiographic septations or preoperative cyst fluid analysis (carcinoe

262 Presence of mural nodules, septations, or lesion multiplicity failed to demonstrate

263 ation of SIN components is not essential for septation per se, but critical for septation to take pla

264 ac crest ablation results in failure of this septation, phenocopying the human heart defect persisten

265 T or US was diagnostic in 95%, with internal septations present in the hepatic cysts.

266 with an important role in interacting with a septation protein subassembly.

267 ol protein 48 (Cdc48), whereas the bacterial septation proteins FtsZ and minD are lacking in Crenarch

268 Osr1 and Pcsk6 interaction in SHF for atrial septation, providing a molecular framework for understan

269 the transcriptional program driving cardiac septation regulates physiologic ventricle partitioning,

270 The process of septation requires precise temporal and spatial organiza

271 M4 in the mycobacterial host led to hindered septation resembling a WhiB2 knockout phenotype whereas

272 endoderm is required for inflow and outflow septation, respectively.

273 al arch arteries and defective outflow tract septation resulting in the formation of a common arteria

274 ial pole malalignment and failure of outflow septation, resulting in a common trunk overriding the ri

275 oss-of-function phenotypes include excessive septation, septal pore degeneration, and uncontrolled Wo

276 After outflow tract septation should occur, embryos treated with cyclopamine

277 NAD, SIDB/MOBA successfully localized to the septation site, indicating that their earlier localizati

278 hich is required for actin ring formation at septation sites and also plays a role in polarized morph

279 tsL, and FtsQ are correctly localized to new septation sites in BC202.

280 sion proteins, FtsA and FtsN, from potential septation sites to clusters that colocalize with ZipA ne

281 flow tract formation, atrial and ventricular septation, skeletal development, and palatogenesis.

282 rtion does not depend on the presence of the septation-specific protein PBP3 and is therefore known a

283 Following polar septation, SpoIIE establishes compartment-specific gene

284 on growth, colony morphology, cell division/septation, surface protein/virulence factor expression,

285 After septation, the alveolar walls thin to allow efficient ga

286 s were analyzed before aorticopulmonary (AP) septation through adult stages.

287 in filamentous cells, suggesting QueE blocks septation through interaction with the divisome.

288 nificance of this tissue to atrioventricular septation through study of the previously uncharacterize

289 ntial for septation per se, but critical for septation to take place in a timely manner in A. nidulan

290 hich oscillate from pole to pole and confine septation to the centers of normal rod-shaped cells.

291 ide at the midcell position well before cell septation was conspicuous.

292 Secondary septation was inhibited, so by days 21 to 28 the mean li

293 n Adriamycin-treated embryos, whereas active septation was observed only in normal foregut morphogene

294 ded intracellular bacterial chains for which septation was restored following drug removal.

295 ically modulating chromosome replication and septation, we can systematically tune the penetrance of

296 rasonographically determined vascularity and septation were not statistically significant predictors.

297 ases required for myocardial development and septation were reduced in Gata4(+/-);Tbx5(+/-) hearts.

298 -thin smooth walls, and no calcifications or septations were identified by applying a validated natur

299 s produced aerial hyphae with no evidence of septation when grown on a traditional osmotically enhanc

300 enses the rate of DNA synthesis and inhibits septation when the rate of DNA synthesis falls below a c

301 and the lesion was poorly circumscribed with septations, which altogether made it difficult to precis