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1 nd the UniProt Metagenomic and Environmental Sequence Database.
2 nd the UniProt Metagenomic and Environmental Sequence Database.
3 el genes with no homologs in current protein sequence database.
4 d unidentified organisms present in the NCBI sequence database.
5 p records found in the Genbank Genome Survey Sequence database.
6 hieve this level of coverage for the current sequence database.
7 ndicated near complete coverage of the viral sequence database.
8 cted to a single genome or across the entire sequence database.
9 between peptide MS/MS spectra and a protein sequence database.
10 using the Los Alamos National Laboratory HIV sequence database.
11 tory of over 85% of all architectures in the sequence database.
12 ectrometry coupled to searching of a protein sequence database.
13 , and among recombinant sequences in the HIV Sequence Database.
14 in homology detection searches over a large sequence database.
15 comparing tandem mass spectra with a protein sequence database.
16 ar modules found in the nonredundant protein sequence database.
17 d model spectra generated from peptides in a sequence database.
18 from the baboon STLV-1 sequence in the NCBI sequence database.
19 his information to build a new non-redundant sequence database.
20 a 50% increase in the size of the underlying sequence database.
21 that is created based on the target protein sequence database.
22 ion about gene structure extracted from cDNA sequence databases.
23 the number of matches found by comparison to sequence databases.
24 of Type I and Type II systems within current sequence databases.
25 for the source organisms represented in the sequence databases.
26 resented by the cultured viruses in existing sequence databases.
27 sented in the INSDC's nucleotide and protein sequence databases.
28 nce clustering analyses is present in public sequence databases.
29 n contained in the rapidly expanding protein sequence databases.
30 ous information for it from existing protein sequence databases.
31 is stored in the scientific literature or in sequence databases.
32 ntains the putative R-M systems found in the sequence databases.
33 eful for screening new submissions to public sequence databases.
34 tified using BLASTx searches against protein sequence databases.
35 ns usually misidentified and misannotated in sequence databases.
36 etoheptane-1,7-dioate aldolase (HpcH) in the sequence databases.
37 e pruning, taxonomic profiling and reference sequence databases.
38 ped to x-ray crystallographic structures and sequence databases.
39 ing for sporadic selenocysteine-Cys pairs in sequence databases.
40 feasible, due to the rapid growth of public sequence databases.
41 d range of taxa, including those lacking any sequence databases.
42 hen determined with the use of public genome sequence databases.
43 show little similarity to other genes in the sequence databases.
44 on-coding RNAs and in the validation of gene sequence databases.
45 enzymes in this pathway were identified from sequence databases.
46 to all chloroplast genomes available in the sequence databases.
47 s have no close match with other peptides in sequence databases.
48 ides from tandem mass spectra and amino acid sequence databases.
49 al SECIS elements and selenoprotein genes in sequence databases.
50 nse regulators that can be identified in the sequence databases.
51 n a query sequence and entries in nucleotide sequence databases.
52 e often mis-annotated as functional genes in sequence databases.
53 s examined through mining of EST and genomic sequence databases.
54 in ASAP based on sequence similarity to five sequence databases.
55 ies have led to the expenential growh of the sequence databases.
56 e it applicable to the management of protein sequence databases.
57 C gene product did not match anything in the sequence databases.
58 nce similarity searches of GenBank and other sequence databases.
59 ch regions that have poor coverage in genome sequence databases.
60 r screening against all endogenous reference sequence databases.
61 function discovery in the rapidly expanding sequence databases.
62 th cancer can be detected by searching tumor sequence databases.
63 d whole-exome sequencing (WXS) data to viral sequence databases.
64 y of accurately identifying viruses in human sequence databases.
65 various lengths against cDNA and/or genomic sequence databases.
66 ethods with nonstandard data sets and custom sequence databases.
67 es for building and using customized protein sequence databases.
68 otations rarely get incorporated into public sequence databases.
69 ecent years has led to the creation of large sequence databases.
70 ndex the entire NCBI nonredundant nucleotide sequence database (a total of 109 billion bases) with an
71 tegrates data from the major DNA and protein sequence databases along with taxonomy, genome, mapping,
72 tegrates data from the major DNA and protein sequence databases along with taxonomy, genome, mapping,
73 tegrates data from the major DNA and protein sequence databases along with taxonomy, genome, mapping,
74 tegrates data from the major DNA and protein sequence databases along with taxonomy, genome, mapping,
75 statistical limits of the PPI structure and sequence databases, amino acid-specific pseudocounts wer
77 ates provides access to a manually annotated sequence database and a database of immunological epitop
79 between them; cd-hit-est clusters a DNA/RNA sequence database and cd-hit-est-2d compares two nucleot
80 g the 300-kb deletion using the human genome sequence database and confirmed the map using various ST
82 Using subcellular fractionation, an improved sequence database and MS we determined the composition,
83 the usefulness of SmartGene IDNS, a 16S rRNA sequence database and software program for microbial ide
84 rchive (ENA), comprising the EMBL Nucleotide Sequence Database and the Ensembl Trace Archive, has ide
85 data, including the GenBank(R) nucleic acid sequence database and the PubMed database of citations a
86 use and human genomes via the NCBI Reference Sequence database and the Sanger Institute miRBase, the
89 metagenomics has led to the rapid growth of sequence databases and enabled a new branch of microbiol
90 gularly updated versions of the main protein sequence databases and is backed up by significant compu
95 uses CMs to search for new family members in sequence databases and to create potentially large multi
96 e utility of BLAST to query against multiple sequence databases and user sequence datasets, and provi
97 WspA has no similarity to entries in the sequence databases and wspA, a possible xenolog, is rest
98 Here, we interrogated a comprehensive RNA-sequencing database and found that human RMS diffusely d
99 quence were selected from the Los Alamos HIV Sequence Database, and a phylogenetic tree was created o
100 ce alignment or profile HMM against a target sequence database, and for searching a protein sequence
101 ARBitrator rapidly updates a public nifH sequence database, and we show that it can be adapted fo
102 technology costs, expanding curated pathogen sequence databases, and better data analysis tools, ther
103 two classes, MgDb for working with 16S rRNA sequence databases, and mgFeatures for marker-gene surve
104 , studies utilize different 16S primer sets, sequence databases, and parameters for sample and databa
105 NA Families Database or annotated in genomic sequences databases, and their phylogenetic distribution
110 lished that despite the annotation of PDP in sequence databases as carboxyphosphoenolpyruvate mutase,
111 ORFan genes, which have no homologues in the sequence databases, as well as the creation of genes de
114 rated with the Gene Expression Atlas and the sequence databases at the European Bioinformatics Instit
117 Pfam is now based not only on the UniProtKB sequence database, but also on NCBI GenPept and on seque
118 similarity relationships among proteins in a sequence database by performing a diffusion operation on
119 xhaustive screening of Plasmodium sp. genome sequence databases by using COWP genes as BLAST queries
120 bacterial species indicate that existing DNA sequence databases carry only a tiny fraction of the tot
121 ta submitted to the International Nucleotide Sequence Database Collaboration (INSDC) against a combin
122 the members of the International Nucleotide Sequence Database collaboration (INSDC) describe each of
123 repository for the International Nucleotide Sequence Database Collaboration (INSDC), comprising the
127 The members of the International Nucleotide Sequence Database Collaboration set out to capture, pres
128 h in analogy to the International Nucleotide Sequence Database Collaboration, aims to provide interna
131 ee partners of the International Nucleotides Sequencing Database Collaboration (INSDC) (Cochrane G, e
132 The partners of the International Nucleotide Sequencing Database Collaboration, which includes the Na
136 .Q184R)] in 14 families from our whole exome sequencing database composed of 1385 patients with inher
137 the rapid changes in size and composition of sequence databases, conservation calculations must be re
138 epitope variability in the Los Alamos HIV-1 Sequence Database, consistent with TCR evolution being d
139 ly submitted to the International Nucleotide Sequence Database Consortium (INSDC) and the assembly re
141 addition of over 100 genomes and the UniProt sequence database, domain data from Pfam, metabolic path
142 iterative scanning and alignment of a large sequence database during which a scoring profile is prog
143 gn long sequences up to 1 Mb against a large sequence database (e.g. the human genome) with a few gig
144 nitially annotated "hypothetical protein" in sequence databases, exhibits an acyl-coenzyme A (acyl-Co
145 om 76% to 87%, and can be used to filter the sequence database for identifying truncated peptides.
146 e analysis pipeline is the ability to scan a sequence database for occurrences of a given motif descr
147 n sequences and subsequently queries the PDB sequence database for the best matches, scans for possib
148 for a protein, the new server will search a sequence database for the closest homolog with an availa
149 , and we evaluate the suitability of current sequence databases for forensic and epidemiological inve
150 (CMs), and uses them to search nucleic acid sequence databases for homologous RNAs, or to create new
152 es of zebrafish EST and whole genome shotgun sequence databases for sequences encoding the sterol-sen
153 rehensive and scalable alternative to native sequence databases for similarity searches and reinforce
154 reported that searches of transcript and DNA sequence databases for wheat and other cereals failed to
155 d extracts all amplicon sequences in a large sequence database from a list of primers and probes, all
158 This result suggests that well developed sequence databases from model plants like Arabidopsis th
159 generation of customized, annotated protein sequence databases from RNA-Seq data; and (ii) accurate
162 n of two of the most prominent cancer genome sequencing databases from different institutes (Cancer C
163 l peptides (not present in reference protein sequence databases) from mass spectrometry-based proteom
164 tified by detailed bioinformatic analysis of sequence databases, function was investigated both by RN
165 try combined with a sample-specific antibody sequence database generated by high-throughput sequencin
174 in animals, interrogation of animal protein sequence databases identified candidates that exhibited
175 pean Molecular Biology Laboratory Nucleotide Sequence Database in Europe and the DNA Data Bank of Jap
178 y ion mass spectra are compared with protein sequence databases in order to identify the amino acid s
179 , the tools will enhance the value of genome sequence databases in support of integrated paleogenomic
181 tectable in other species represented in the sequence databases, including 19 other mammals with draf
183 ntologies and a fully-structured markers and sequences database integrated with genome browsers and m
186 ing these names to the associated entries in sequence databases is becoming increasingly important fo
187 ch means that a lot of information in public sequence databases is not linked to formal taxonomic nam
188 quence homology from genomic and metagenomic sequence databases is straightforward, prediction of cor
189 nsembl Trace Archive and the EMBL Nucleotide Sequence Database, known together as the European Nucleo
190 tion of structural databases such as MSD and sequence databases like UniProt is the absence of up to
191 ot rely on alignment, assembly and reference sequence databases; making it fast and scalable for larg
195 strands and the absence of the mutation from sequence databases, normal adjacent tissues, and other c
197 findings, we screened our ADV clinical-study sequence database of 853 patients and identified 4 who,
198 66 were identified in a large (>600 strains) sequence database of fimH-positive E. coli strains.
201 esult of bioinformatic screening of the gene sequence database of the parasitic protozoan Leishmania
203 he contained modules allow for formatting of sequence databases, peptide spectrum matching, statistic
207 of diverse confident homologs in the current sequence databases provide an increased quality of simil
210 ceeded to extract information from unlabeled sequence databases relevant for various protein predicti
211 y database, PlantCyc, and a reference enzyme sequence database, RESD, for annotating metabolic functi
212 closely related variant from curation of the sequence database resulted in a native-like dimeric TIM
213 ST screening of the Toxoplasma gondii genome sequence database resulted in identification of a gene e
214 AST screening of a complete C. parvum genome sequence database resulted in identification of eight ad
215 oinformatics and molecular modelling to mine sequence databases, resulting in a diverse panel of enzy
218 Alignment of hydrogenase sequences from sequence databases revealed many rare substitutions; the
228 ough its web interfaces for analyses such as sequence database search, statistical validation, and qu
230 group (ESG) method, which performs iterative sequence database searches and annotates a query sequenc
232 -gel proteolysis, peptide mapping by MS, and sequence database searches for protein identification, w
234 rives its strength from several sources: (i) sequence database searches to retrieve additional homolo
236 t in structure database searches and initial sequence database searches; however, the enhancements sh
238 itive and false negative sequence matches in sequence database searching of tandem mass spectrometry
239 ion of peptides and proteins heavily rely on sequence database searching or spectral library matching
243 eed-up is independent of the size of growing sequence databases, SeqVec provides a highly scalable ap
244 gainst the germline gene databases and other sequence databases simultaneously to minimize the chance
248 ch services, the users can search mainstream sequence databases such as EMBL-Bank and UniProt, and mo
249 e over 200 homologs of similar size in large sequence databases such as UniProt, with pairwise sequen
251 , we identified a bacteriophytochrome in the sequence database that is monomeric in truncated form an
252 e protein matching, however, have such large sequence databases that the resulting list of seeds cann
253 iously unreported gene (not present in human sequence databases) that encodes an inwardly rectifying
254 show that as more sequences are added to the sequence databases the fraction of sequences that Pfam m
255 n to maintaining the GenBank(R) nucleic acid sequence database, the National Center for Biotechnology
256 n to maintaining the GenBank(R) nucleic acid sequence database, the National Center for Biotechnology
257 tion to maintaining the GenBank nucleic acid sequence database, the National Center for Biotechnology
258 n to maintaining the GenBank(R) nucleic acid sequence database, the National Center for Biotechnology
259 tion to maintaining the GenBank nucleic acid sequence database, the National Center for Biotechnology
260 tion to maintaining the GenBank nucleic acid sequence database, the National Center for Biotechnology
261 many sources, including the EMBL Nucleotide Sequence Database, the UniProt Knowledgebase, InterPro,
262 ty, and those involved in development of HCV sequence databases, the Hepatitis Virus Database (Japan)
263 s because of the lack of appropriate protein sequences databases, thus restricting the analysis on co
264 es a search mode using a query STS against a sequence database to augment the previously available mo
265 equences against the U12-type spliced intron sequence database to examine whether some events could o
266 cognition), we constructed a three-locus DNA sequence database to facilitate molecular identification
267 beyond plant species, we plan to expand our sequence database to include the fully sequenced genomes
268 We use the largest publicly available exome sequence database to show that this key clinical service
269 nterface allows a range of different protein sequence databases to be searched including the SCOP dat
270 To test this concept, we searched public sequence databases to identify putative LHE open reading
271 pportunities for laboratories to parse large sequencing databases to identify proteins and noncoding
272 ced by searching the spectra against a decoy sequence database, to provide a model of the null score
276 ood ratio score for each position in a given sequence database, uses established dynamic programming
277 hat pass all filters are then located in the sequence database using a precomputed index, and an accu
278 e searched against an appropriate nucleotide sequence database using tools such as BLAST to examine t
280 ion) of gene and protein function over large sequence databases, using phylogenetic trees to extrapol
282 os Alamos National Laboratory Oral Pathogens Sequence Database was identified, which was strongly ind
284 -length (V4) sequence diversity in the SILVA sequence database, we further estimate that there exist
287 ive BLAST searches of public and proprietary sequence databases, we further identified orthologous se
288 vantage of the ongoing exponential growth of sequence databases, we go significantly beyond anecdotal
290 od and semen samples from the Los Alamos HIV Sequence Database were analyzed to ascertain a male geni
292 ound changes in the taxonomic composition of sequence databases, which are effectively redefining the
293 report a collection of non-redundant patent sequence databases, which cover the EMBL-Bank nucleotide
294 pe-phenotype relations from population-based sequence databases, which is an integral facet of person
295 log with known 3D structure when searching a sequence database with an arbitrary query sequence.
296 d, we conducted a BLASTN search of the maize sequence database with queries from two previously descr
297 proximately equal to 200 bp) against a large sequence database with small memory footprint (e.g. ~2 G
298 rpreted product ion spectrum against protein sequence databases with varying degrees of annotation, c
299 of de novo and spectra matching to a protein sequence database, with up to 4077 peptides (2725 modifi
300 atch, is able to cross-link any of the major sequence databases within a few seconds on a modest desk