ライフサイエンスコーパス: sequence homology

1 gly than GC-rich duplexes, regardless of the sequence homology.

2 discrimination of miRNA sequences with high sequence homology.

3 discrimination of miRNA sequences with high sequence homology.

4 ow the efficiency of repair is influenced by sequence homology.

5 classified by their receptor specificity and sequence homology.

6 183, -96 and -182, is also a miR family with sequence homology.

7 lipid kinases, despite the absence of clear sequence homology.

8 SKI/SNO/DAC domain, despite lacking obvious sequence homology.

9 high structural similarity despite their low sequence homology.

10 tilis, SpaI, despite the lack of significant sequence homology.

11 the Holliday junctions to the boundaries of sequence homology.

12 oup was highly variable and not predicted by sequence homology.

13 or genes and estimate their likelihoods from sequence homology.

14 nnel analog) without sharing any significant sequence homology.

15 nuclease YbeY, even though they do not share sequence homology.

16 to four clusters based on gene structure and sequence homology.

17 uses is very limited, despite high levels of sequence homology.

18 tail genes even in the absence of detectable sequence homology.

19 r features, MFS transporters share only weak sequence homology.

20 art of an X-Y pair, with NLGN4Y sharing ~97% sequence homology.

21 humans on the basis of their high degree of sequence homology.

22 nt beta-galactosidase showed high amino acid sequence homology.

23 ors, respectively, despite their significant sequence homology.

24 ATX1-Like Copper Chaperone (CCH), share high sequence homology.

25 some annotations are solely on the basis of sequence homology.

26 an array of cell-surface receptors that lack sequence homology.

27 a melanogaster, and Mus musculus revealed no sequence homology.

28 ntiporter NhaA, despite having no detectable sequence homology.

29 AD51 paralogue genes have been identified by sequence homology.

30 ring transcription initiation despite little sequence homology.

31 codes biuret hydrolase and has close protein sequence homology.

32 n ported to newly sequenced genomes by using sequence homology.

33 share the same architecture on the basis of sequence homology.

34 itiator, TbORC1/CDC6, has been identified by sequence homology.

35 eactivity generally correlated with allergen sequence homology.

36 d nature of their functional commonality and sequence homology.

37 factor-beta superfamily sharing 89% protein sequence homology.

38 termed SMASH, for short multiply aggregated sequence homologies.

39 were annotated as motility-related based on sequence homologies.

40 Despite low sequence homology (48.2%-77.3% similarity), all ortholog

41 Low sequence homology (88% average pairwise identity) and fr

42 re a family of proteins with no structure or sequence homology, able to elicit a sweet sensation in h

43 A nucleoprotein filaments efficiently locate sequence homology across genomic DNA remains unclear.

44 LlaBIII shares >95% amino acid sequence homology across its first three protein domains

45 but is difficult to achieve due to the high sequence homology across the class I PI3K isoforms.

46 Despite sequence homology across the PAR isoforms, discovery of

47 Based on sequence homology, AdPLA is part of a small family of ac

48 BESs were searched for sequence homology against known databases.

49 m the identification of short regions of DNA sequence homology, also known as microhomology, at chrom

50 Despite high sequence homology among different deer species, a fallow

51 Considering the high sequence homology among DNA of H. pylori isolated from s

52 roperties of short length, low abundance and sequence homology among family members, it is difficult

53 omoter using the following methodologies: 1) sequence homology among several mammalian species, 2) DN

54 Because of the substantial level of sequence homology among sodium channels, our data also i

55 However, sequence homology among them is limited.

56 The low sequence homology among unrelated kinases with bulky DFG

57 Sequence homology among viruses and ability of T cells t

58 RFs) and does not require linkers, adaptors, sequence homology, amplification or mutation (domesticat

59 thermal denaturation, biochemical assays and sequence homology analysis all strongly support defects

60 inactivation of firefly luciferase, and (iv) sequence homology analysis indicated that ICP22 contains

61 Sequence homology analysis revealed a potential canonica

62 ue of the mouse Rosa26 locus through genomic sequence homology analysis.

63 conserved enhancers in the absence of overt sequence homologies and over extensive evolutionary dist

64 predict organismal metabolic networks using sequence homology and a global metabolic network constru

65 Sister chromatids provide near-perfect sequence homology and are therefore the preferred templa

66 2 cytotoxic factors exhibited 50% amino acid sequence homology and bound to the same receptor, they c

67 TssL and TssM share sequence homology and characteristics with two component

68 Here we show that, despite sequence homology and coexpression from the same operon,

69 of M. silvestris and eukaryotic Tdms have no sequence homology and contrasting characteristics.

70 EF-P shares sequence homology and crystal structure with eIF5A, but

71 EptC shares significant amino acid sequence homology and domain structure with the MukB pro

72 FcepsilonR1gamma and CD247 share high sequence homology and form disulphide-linked homodimers

73 he depupylase Dop share close structural and sequence homology and have a common evolutionary history

74 ve markedly different patterns of evolution; sequence homology and negative selection were highest in

75 or open pan-genomes and share generally high sequence homology and number of core genes including vir

76 Despite sharing up to 78% sequence homology and overlapping expression profiles in

77 Sequence homology and phylogenetic analysis indicated th

78 prehensive systems-scale analysis of genomic sequence homology and phylogenetic relationships among C

79 share evolutionary ties with a high level of sequence homology and predicted structural homology.

80 ase, where the synaptic joints either locate sequence homology and progress to a post-synaptic joint,

81 Based on sequence homology and secondary structure prediction, we

82 They can be divided in two classes based on sequence homology and the presence of an insertion withi

83 y to other profilins correlated with overall sequence homology, and 2 immunodominant epitope regions

84 like canonical Rap1 effectors despite little sequence homology, and disruption of the binding strongl

85 SARS-CoV and MERS-CoV FPs share a high sequence homology, and here, we investigated whether Ca(

86 ubtle structural similarities independent of sequence homology appear to sustain operational equivale

87 e bat-associated viruses because of its high sequence homology (approximately 90% in most genes) to i

88 l set of gene expression data in addition to sequence homologies are instrumental in the assignment o

89 st that not all Pooideae grass epitopes with sequence homology are cross-reactive.

90 llowed differentiation of proteins with high sequence homology as evidenced by de novo sequencing of

91 Despite sequence homology at the active site and biophysical pro

92 occurs by a mechanism that may require some sequence homology at the recombination junction and that

93 In first step, sequence homology-based genetic analysis of a set of 50

94 A major limitation of sequence homology-based identification for highly diverg

95 Despite the sequence homology between acid-sensing ion channels (ASI

96 r small size, low natural abundance and high sequence homology between family members they are challe

97 Given the high amino acid sequence homology between fish enzymes, a 3-D structure

98 In addition, sequence homology between frog and mammalian Cerberus is

99 Based primarily on a sequence homology between Golgin45 and GM130, we found t

100 Capitalizing on the complete sequence homology between human and mouse in the heparin

101 Despite the sequence homology between RON and MET receptor tyrosine

102 The unexpected nucleotide sequence homology between SLE patient-derived autoantibo

103 Thus, sequence homology between T cell epitopes of 2 self-prot

104 However, on the basis of sequence homology between the 5 Ebolavirus species, we h

105 ial collaboration in actin assembly, but low sequence homology between the Basic domains of Drosophil

106 The high sequence homology between the D3R and D2R, especially wi

107 tor has been challenging because of the high sequence homology between the D3R and the dopamine D2 re

108 These methods, which rely on sequence homology between the ends of DNA parts, have be

109 vidual antigenic regions correlated with the sequence homology between the MVA- and DNA Gag-encoded i

110 rved from bacteria to man, despite a lack of sequence homology between the resolvases.

111 me drive suppression is probably mediated by sequence homology between the suppressor and distorter t

112 ly, SNGD-mediated gene editing requires long-sequence homology between the target gene and repair tem

113 y, EigenTHREADER does not depend directly on sequence homology between the target protein and entries

114 Strong sequence homology between the three ORMDL genes and ORMD

115 : the similarity in action suggests that the sequence homology between the two compounds might have a

116 Despite the low sequence homology between the two enzymes (29% identity)

117 en co-expressed in COS-7 cells, despite high sequence homology between the two enzymes.

118 ne coupling subunits do not share an obvious sequence homology between the two transporter families.

119 Despite limited sequence homology between the vertebrate and Drosophila

120 ghly challenging owing to the glutamate-site sequence homology between these proteins.

121 esponses were rarely elicited when there was sequence homology between vaccine immunogen and endogeno

122 composed of several isoforms that share high sequence homology but differ in functional characteristi

123 embrane protein of unknown function with low sequence homology but high structural homology to both y

124 tional modeling, we studied ORs sharing high sequence homology but with different response properties

125 ide bonds are quite diverse and share little sequence homology, but all contain a CXXC catalytic acti

126 (RecA-ssDNA) filament searches a genome for sequence homology by rapidly binding and unbinding doubl

127 uch as short sequence, low concentration and sequence homology challenge routine techniques.

128 d developed an acute HBV infection with 100% sequence homology, compared with HBV inoculum.

129 The confounding effects of sequence homology, complexity of competing cleavages and

130 tive and highest true positive rate assesses sequence homology, contact number and if mutation involv

131 As predicted by sequence homology, CT189/190 are the two subunits of DNA

132 Evolutionary analysis and sequence homology data revealed P450 family blooms in oo

133 paya lines resistant to PRSV isolates in the sequence-homology-dependent manner have been developed i

134 Sequence homology diagrams were constructed to compare e

135 n of CER2 as a BAHD acyltransferase based on sequence homology does not fit with CER2 catalytic activ

136 Thus, despite limited sequence homology, Drosophila and vertebrate APCs exhibi

137 Moreover, despite no sequence homology, Ec-dGTPase and SAMHD1 share similar a

138 M2) are functional analogs, they have little sequence homology, except for a conserved HXXXW motif, w

139 Despite a lack of sequence homology, FANCB and FAAP100 adopt similar struc

140 pathogen specific with minimum interspecies sequence homology for the design of Flavivirus vaccines.

141 le identification of natural LHE proteins by sequence homology from genomic and metagenomic sequence

142 Despite significant sequence homologies, functional differences between the

143 putational approaches based, for example, on sequence homology, gene co-expression and phylogenetic p

144 While sequence homology has been a standard to annotate metabo

145 ver, low NLR expression and high intrafamily sequence homology hinder their accurate annotation.

146 Sequence homology identified the pyridoxal phosphate-dep

147 Detailed analysis of sequence homology identifies canonical TIR motifs as wel

148 The notion that sequence homology implies functional similarity underlie

149 itope in the CH3 domain of hFc that has high sequence homology in all four hIgG isotypes (hIgG(1-4)),

150 , of which 3,761 are novel with little or no sequence homology in any existing databases.

151 e virulent P18 strain shows a high degree of sequence homology in the bisegmented genome between the

152 rison of the resulting peptides showed large sequence homology in the phosphopeptides released by try

153 The six clones demonstrated some sequence homology in the region 2600-2605 and incorporat

154 B-cell receptors (BCRs) with a high level of sequence homology in the variable domains of the heavy a

155 Despite substantial sequence homology in their core domains, nTop1 and mitoc

156 PLN and SLN have significant sequence homology in their transmembrane regions, sugges

157 identify analogous folds where little or no sequence homology information is.

158 that makes use of both network topology and sequence homology information, based upon the observatio

159 p38gamma shares high sequence homology, inhibition sensitivity and substrate

160 Inference of sequence homology is inherently an evolutionary question

161 This low sequence homology is the result of the inclusion of diso

162 ften persists throughout evolution even when sequence homology is undetectable, As macromolecules can

163 tionic amino acid transporters (CATs) due to sequence homology, may represent system c.

164 This command-line application integrates sequence homology, nucleotide composition, coverage and

165 Lastly, we identified short-sequence homologies of surface-exposed residues within t

166 We notice significant sequence homology of AIM2(PYD) with the hydrophobic patc

167 conservation of neural expression and strong sequence homology of all CORL proteins suggests that thi

168 Based on sequence homology of butelase 1, we identified AEPs and

169 Despite the high sequence homology of the two domains, a network of large

170 Comparison of the structure and sequence homology of TYK2 between human and preclinical

171 Our data indicate that due to linear sequence homology, part of the MOG35-55-specific T cell

172 Gene sequence homology predicts that the sioxanthin biosynthe

173 ufficient coverage (<20x read depth) or high sequence homology (pseudogenes) are complemented by ampl

174 cue model for SV with breakpoints located in sequence homology regions.

175 Is of Colias and the silkmoth, but no intron sequence homology remains.

176 Most methods for biological sequence homology search and alignment work with primary

177 tion tools RepeatMasker and Censor depend on sequence homology search tools such as cross_match and B

178 For allergen identification protein sequencing, homology search and mass spectrometry were a

179 t on Arabidopsis thaliana genes or 2) coding sequence homology searches using curated databases.

180 Sequence homology searches were performed to extend ZU5-

181 face profiles, collected from structural and sequence homology searches, with a physics-based energy

182 and are classified into four groups based on sequence homology (SEPT2, SEPT3, SEPT6, and SEPT7 groups

183 f these proteins, which share no discernible sequence homology, share a striking structural similarit

184 selected with an intent to evenly sample the sequence homology space and to focus on species in which

185 t to the Toll/IL-1R domain of TLR10 with low sequence homology, substantial differences were observed

186 Despite no obvious sequence homology, the dV architecture shows a striking

187 Despite a lack of sequence homology, the genes are aligned in a head-to-ta

188 Despite very low sequence homology, the major capsid proteins of double-s

189 two enzymes share approximately 50% protein sequence homology, the membrane topology of VKOR is stil

190 Thus, despite low overall sequence homology, the production of infectious virus is

191 Although the RSKs have a high degree of sequence homology, their functional differences in cance

192 Although calbindin and S100B have a low sequence homology, they seem to activate IMPase-1 in a s

193 Dscam and vertebrate Pcdh proteins share no sequence homology, they seem to underlie similar strateg

194 AChR subtypes (M1-M5) share a high degree of sequence homology, they show pronounced differences in G

195 SSGP-71 proteins lack sequence homologies to other proteins, but their structu

196 es significant structural similarity but not sequence homology to a group of enzymes that bind to and

197 Sequence homology to a putative yeast thiamine (vitamin

198 Sequence homology to A1cf, the RNA-binding subunit of th

199 he green alga Chlamydomonas reinhardtii with sequence homology to animal cryptochromes and (6-4) phot

200 d executor type R genes show no considerable sequence homology to any known R genes.

201 d executor type R genes show no considerable sequence homology to any known R genes.

202 st since the receptor-binding domain 1 lacks sequence homology to any other known toxin, and the rece

203 proteins (LipA and LipB) that had amino acid sequence homology to bacterial adhesins and structural h

204 Furthermore, this domain has been shown by sequence homology to be present in all bacterial L-serin

205 CLDs have high degrees of sequence homology to cathelin, a protein isolated from p

206 (CD99L2) is a membrane protein with moderate sequence homology to CD99, which initiates cell aggregat

207 bout half of the components of the TCPM show sequence homology to components of the previously analys

208 ator of Cdk1 and Cdk2 that has no amino acid sequence homology to cyclins, are sterile and display me

209 EnvD showed strong sequence homology to dienelactone hydrolases from other

210 f approximately 70 amino acids and have high sequence homology to each other (>85% identity).

211 ces cerevisiae MTase Yjr129c, which displays sequence homology to FAM86A, is a functional FAM86A orth

212 ar domains KL1 and KL2, each of which shares sequence homology to glycosyl hydrolases.

213 a class of vertebrate proteins that exhibits sequence homology to innexins, the invertebrate gap junc

214 embers of a tick protein family bearing high sequence homology to Japanin are also likely to bind cho

215 ammaherpesvirus 68 (MHV68) ORF73 (mLANA) has sequence homology to Kaposi's sarcoma-associated herpesv

216 However, Mmp10 has little sequence homology to known methylases, suggesting this e

217 xtract features that can effectively capture sequence homology to known ncRNA families.

218 r short (2-100 amino acids) peptides with no sequence homology to known proteins.

219 One of these miRNAs, miR-J8, has seed sequence homology to members of the cellular miR-17/20/1

220 SynCaK displays significant sequence homology to MthK, a calcium-dependent potassium

221 ng the Crenarchaeota branch, and bear little sequence homology to other DNA polymerase families.

222 This region has no sequence homology to other known fibrinogen binding prot

223 al virus proteins display very low levels of sequence homology to other proteins listed in the public

224 ew major allergen was isolated, which showed sequence homology to peritrophins, which contain chitin-

225 Based on sequence homology to pilins in Gram-negative bacteria, C

226 SdbA shows low sequence homology to previously identified oxidoreductas

227 r analysis" yielded heavy chains with little sequence homology to previously identified VRC01 class h

228 he hidden Markov model library that provides sequence homology to SCOP structural domains remains unc

229 potassium conductance domains that show high sequence homology to the bacterial TrkA family of K(+) t

230 nsmembrane-helix (6-TM) domain, which has no sequence homology to the canonical tetrameric K(+) chann

231 e, and the core herpesvirus genes had strong sequence homology to the corresponding KSHV genes.

232 GDAP1 contains primary sequence homology to the GST superfamily; however, the q

233 to-inhibitory domain within Snf2h that bears sequence homology to the H4 tail, abolishes the linker-l

234 These proteins have sequence homology to the N-terminal domain (NTD) of the

235 Despite close sequence homology to the protease cathepsin L, the silic

236 associated with metabolosomes (PduL) has no sequence homology to the PTAC ubiquitous among fermentat

237 cludes a rhodanese-fold in accordance to its sequence homology to the rhodanese family of sulfurtrans

238 cific sgRNA is not uniquely defined by exact sequence homology to the target site, thus unintended of

239 elanogaster alpha7 (Dalpha7) has the closest sequence homology to the vertebrate alpha7 subunit and i

240 Despite showing no primary sequence homology to TNF family cytokines, UL141 binds t

241 Based on sequence homology to TNF-alpha, now a total of 19 member

242 entified via experimental evidence, based on sequence homology to Trm2, two candidates currently exis

243 Despite previous failure in detecting any sequence homology to ubiquitin, the folded state was det

244 Despite having no sequence homology, TPSs and IDSs share a conserved "alph

245 al analysis of the mutant CWPS combined with sequence homology, transmission EM, and phage sensitivit

246 s capable of recognizing extremely divergent sequence homology, we identified a MYRF protein domain d

247 Based on sequence homology, we identified a single M. polymorpha

248 Based on sequence homology, we identify IPLA-1 as the closest C.

249 proteins of these viruses show the greatest sequence homology, we tested hyperimmune antisera prepar

250 A strong genome colinearity and sequence homology were observed between MneRV2 and RRV26

251 eyi (Hd-CDT), which share limited amino acid sequence homology, were directly compared.

252 omyces lactis Hsv2, which shares significant sequence homologies with its three Saccharomyces cerevis

253 inically significant nucleic acids and their sequence homology with abundant wild-type nucleic acids.

254 BM2 shares little sequence homology with AM2, except for a conserved HxxxW

255 NM; and (iii) the LnmJ-SH domain, sharing no sequence homology with any other enzymes catalyzing C-S

256 ciparum SSB (Pf-SSB) shares a high degree of sequence homology with bacterial SSB proteins but differ

257 protease and signaling inhibitor TIKI shares sequence homology with bacterial TraB/PrgY proteins, inh

258 se, but further work revealed that it shared sequence homology with beta-lactamase/metallo-beta-lacta

259 system, we discovered an adhiron that shared sequence homology with C3 and abolished C3-induced prolo

260 One adhiron (A6) was found to have a sequence homology with C3 and studied further.

261 ClsC has sequence homology with ClsA and ClsB, which all belong t

262 They often shared sequence homology with co-expressed genes and contained

263 They share a high sequence homology with cyclotides but are biosynthetical

264 d3 is presumed to be palmitoylated, based on sequence homology with Drd2, but the functional attribut

265 he two O. tsutsugamushi isolates shared >99% sequence homology with each other, reflecting the consis

266 Pseudoenzymes are proteins that have sequence homology with enzyme families but that are prov

267 The HLA-DR-presented GNS peptide has marked sequence homology with epitopes from sulfatase proteins

268 LsbB shares significant sequence homology with five other leaderless bacteriocin

269 rhodopsins from cryptophyte algae show close sequence homology with haloarchaeal rhodopsin proton pum

270 cus contains more than 50 genes sharing high sequence homology with hexose transporters in Saccharomy

271 ne viral miRNA, miR-K12-11, shares 100% seed sequence homology with hsa-miR-155, an oncogenic human m

272 S27, UL33, and UL78, which present important sequence homology with human chemokine receptors.

273 the deduced Cq-IGFBP was shown to share high sequence homology with IGFBP family members from both in

274 Although it has low amino acid sequence homology with known 2-oxoglutarate-dependent di

275 ound ubiquitin ligase that bears significant sequence homology with mammalian Hrd1 and mediates stero

276 ntial to viral transcription and that shares sequence homology with members of the paramyxoviruses an

277 (DENV1 to -4), which share a high degree of sequence homology with one another.

278 erotypes (DENV1 to -4) which share 67 to 75% sequence homology with one another.

279 of the S1 helix, as a consequence of its low sequence homology with other Kv family members.

280 S2 shares no sequence homology with other retroviral factors known to

281 NS1 C-terminal residues 305-311, which share sequence homology with Plg residues 590-597.

282 Hp0267 shares no sequence homology with previously characterized ADDs, ye

283 we demonstrate that NUCKS1 shares extensive sequence homology with RAD51AP1 (RAD51 associated protei

284 ICMT has no discernible sequence homology with soluble methyltransferases, and a

285 vel ORFs, which we name cylc-1 and -2, share sequence homology with stathmins and encode small, very

286 imensional models of MdtB and MdtC, based on sequence homology with the AcrB transporter, also suppor

287 It exhibits strong sequence homology with the bacteriophage T7 gene 4 prote

288 Even though it shares low sequence homology with the cannabinoid receptors CB(1)R

289 ized the wheat LEA protein TdLEA3, which has sequence homology with the group of LEA_4 proteins that

290 nfected with HCV that had more than 95% NS5B sequence homology with the HCV strains of the 3 case pat

291 erminal domain (C domain) shares significant sequence homology with the OmpA-like family of peptidogl

292 d, and P4 proteins of WMoV exhibited limited sequence homology with the orthologous proteins of other

293 PLR1) was identified in Arabidopsis based on sequence homology with the protein in yeast.

294 e inserted, as the position is determined by sequence homology with the recombination primers.

295 Although StnA has no significant sequence homology with the reported alpha/beta-fold hydr

296 Class C methylases share significant sequence homology with the RS enzyme, HemN, and may bind

297 The endogenous protein has 88.0% sequence homology with the theoretically predicted Gly m

298 It shares sequence homology with three enzymes (STEAP2-STEAP4) tha

299 acy by up to 40% for species which have high sequence homology within their genus.

300 eptors ERalpha and ERbeta share considerable sequence homology yet exert opposite effects on breast c