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1 ourse through this field of science has been serendipitous.
2 drugs for tremor disorders has been largely serendipitous.
3 re valid, but obtaining ictal SPECT is often serendipitous.
4 of these edited transcripts has always been serendipitous.
6 diphtheria tetanus vaccination may have been serendipitous, a result of a nonspecific bystander activ
7 ing sites and lead compounds has been mostly serendipitous, achieved through high-throughput screenin
9 ty in synthetic hosts are scarce and largely serendipitous, among other things because it is hard to
11 discovery of useful polypharmacology remains serendipitous and is challenging to characterize and val
12 ormable crystals remains limited to cases of serendipitous and laborious trial-and-error approaches,
13 ties, their discovery has traditionally been serendipitous and often requires post hoc rationalizatio
14 erapeutic uses for approved drugs-is often a serendipitous and opportunistic endeavour to expand the
15 tes for achieving one phase over another are serendipitous, and the links among precursor reactivity,
16 However, their discovery has typically been serendipitous, and the rules governing their identificat
22 ngle factor or key innovation, but require a serendipitous combination of both intrinsic biotic and e
24 the interstellar medium.) Here we report the serendipitous detection of cometary pick-up ions, most p
26 advances have been fuelled, in part, by the serendipitous development of two distinct FGF23 assays t
27 nd protein folding in E. coli, together with serendipitous discoveries and the availability of improv
29 processes relies on both rational design and serendipitous discoveries from innovative tools such as
30 nally, strategies to reduce bias and promote serendipitous discoveries have further strengthened HTE'
35 or 1000-fold potency improvements are often serendipitous discoveries that can be considered "magica
38 ved treatments for depression have come from serendipitous discovery and are ineffective in nearly 30
48 nea pig serum kills lymphoma cells marks the serendipitous discovery of a new class of anti-cancer ag
49 alcium indicator (Lck-GCaMP3), we report the serendipitous discovery of a new type of Ca(2+) signal i
51 ogically distinct nanocarbons, including the serendipitous discovery of a structure containing a new
55 -cyclododecatriene with N(2)O has led to the serendipitous discovery of an array of hitherto unknown
57 atment of gingival carcinoma that led to the serendipitous discovery of an unrelated and unusual syst
65 isubstituted imidazole inhibitors led to the serendipitous discovery of inhibitors that target the dr
70 recollection of the events triggered by our serendipitous discovery of oestrogenic activity in plast
71 plexes studied and can be traced back to the serendipitous discovery of Prussian blue by Diesbach in
74 th cucurbit[8]uril (CB[8]), initiated by the serendipitous discovery of salt forming a tightly bound
77 iting opportunities for rational rather than serendipitous discovery of therapeutics for schizophreni
79 d the density of such objects implied by the serendipitous discovery of this star is consistent with
80 gand interactions were largely the result of serendipitous discovery rather than rational design.
81 Genomic sequence analysis of Poli led to the serendipitous discovery that 129-derived strains of mice
82 ent siRNAs in Escherichia coli, based on the serendipitous discovery that ectopic expression of p19,
84 nder ball-milling conditions have led to the serendipitous discovery that manganese metal can mediate
87 ity associated with middle T antigen and our serendipitous discovery that this activity was specific
90 evolution of this reaction from the initial serendipitous discovery to its general synthetic scope i
98 etimes and lower/invariant efficiencies, the serendipitous effect of D(2) O as a beneficial solvent a
108 is preparation in the early 1980s, we made a serendipitous finding of a novel presynaptic inhibitory
109 number of clinical studies have reported the serendipitous finding of high rates of objective clinica
111 zing the host range of this phage, we make a serendipitous finding that links the acquisition of a ph
113 al orexin receptor antagonist and describe a serendipitous finding that triggered a medicinal chemist
117 As is often the case, chance discovery and serendipitous findings played a role in the evolution of
119 merely associated with isolated zones where serendipitous happenstance has produced mineralisation.
120 very of material-specific details is usually serendipitous, if possible, and ii) inherent biases that
121 olite chemistry, but their formation remains serendipitous in reticular chemistry when designing zeol
122 tensive research in better understanding the serendipitous incorporation of emissive guest species wi
124 opy PCOS with partial penetrance, due to the serendipitous insertion of a Gata4 promoter-driven trans
126 ng back more than 3 billion years, creates a serendipitous interaction with the serine OH that is dif
129 the Scholl reaction have traditionally been serendipitous, lacking a systematic approach for synthes
130 of their biological impacts have mostly been serendipitous, limiting our understanding of their evolu
131 work but rather focus on decisive findings, serendipitous, lucky moments when major advances made th
132 generation SERMs/SERDs were discovered in a serendipitous manner, this review will highlight how our
133 nk DNA." This model arose from analysis of a serendipitous mouse mutant in which a transgene insertio
135 n 1992, Jere Meredith and I followed up on a serendipitous observation and showed that matrix depriva
137 of core formation by taking advantage of our serendipitous observation of large membrane-enclosed str
138 driven by knowledge of disease mechanisms or serendipitous observation rather than by systematic ende
141 enetic nature of MDS may explain in part the serendipitous observation that it is the disease most re
147 posing occurred in academia and was based on serendipitous observations or perceived disease similari
149 the historical context, scientific reasons, serendipitous observations, and landmark discoveries tha
155 rity can be used to rationalize an otherwise serendipitous process, we employed 3D shape-based virtua
156 uence, most synthetic work has been based on serendipitous processes in the search for large magnetic
161 types or mixed-metal compositions are often serendipitous, require postsynthetic modification strate
162 on of a protoilludane to a marasmane through serendipitous ring contraction, which provides experimen
163 of a visible lesion (such as a polyp) or the serendipitous sampling of a dysplastic focus during "bli
166 tal size and aspect ratio, where crystals of serendipitous size are harvested from crystallization so
168 reatment options that could replace previous serendipitous therapeutic approaches in refractory PRP.
169 The discovery of these four galaxies was serendipitous; they are close to their companion quasars
170 e morc TgN(Tyr)1Az(microrchidia) mutation, a serendipitous transgenic insertional mutation which caus
171 broad, including medication side effects or serendipitous use of chronotropic stimulating drugs.