ライフサイエンスコーパス: serine protease

1 otease 4 (HAT-L4) is a type II transmembrane serine protease.

2 responsible for the activation of neutrophil serine proteases.

3 , which regulate the proteolytic activity of serine proteases.

4 n, a protease homologous to other allosteric serine proteases.

5 nown to mostly act on potassium channels and serine proteases.

6 for generating target-tailored inhibitors of serine proteases.

7 ants specifically inhibit different types of serine proteases.

8 atC without affecting those of elastase-like serine proteases.

9 ivary gland with the primary proteases being serine proteases.

10 m because it is actually a poor inhibitor of serine proteases.

11 haracterizing the P2' specificity of various serine proteases.

12 ptidyl arginine deiminase 4, or digestion by serine proteases.

13 es most of tissue-degrading elastase-related serine proteases.

14 ith selectivity against most of the relevant serine proteases.

15 ions with FD and gain selectivity against S1 serine proteases.

16 noma (HAT/DESC) cluster of membrane-anchored serine proteases.

17 he outer domain was cleaved by membrane type-serine protease 1 (MT-SP1) present in the tumor microenv

18 Mutations in the human serine protease 1 gene (PRSS1), which encodes cationic t

19 king mannose-binding lectin (MBL)-associated serine protease-1 (MASP-1) and MASP-3 contain zymogenic

20 lectin-11, mannose-binding lectin-associated serine protease-1, and mannose-binding lectin-associated

21 ous studies have reported that transmembrane serine protease 2 (TMPRSS2) is essential for activation

22 th host proteases, principally transmembrane serine protease 2 (TMPRSS2), promotes cellular entry.

23 databases within ACE2/SLC6A19/transmembrane serine protease 2 (TMPRSS2), warranting genomic enrichme

24 converting enzyme 2 (ACE2) and transmembrane serine protease 2 (TMPRSS2).

25 ative C3 by mannan-binding lectin-associated serine protease-2 bound to LP-activation complexes captu

26 ctor enzyme mannan-binding lectin-associated serine protease-2 can activate native complement C3 in a

27 ase-1, and mannose-binding lectin-associated serine protease-2.

28 LP-specific mannan-binding lectin-associated serine protease-2.

29 obial peptides are stimulated via hemolymph (serine) protease 5 (HP5) in Manduca sexta Previous studi

30 In MEPs of transmembrane serine protease 6 knockout (Tmprss6-/-) mice, which exhi

31 ing lectin, together with mannose-associated serine proteases, activates the lectin pathway of the co

32 this technique, a diverse profile of MMP and serine protease activities was characterized in breast c

33 les, and syncytium formation, and endogenous serine protease activity did not contribute greatly to i

34 ormal and, compared with SD therapy, reduced serine protease activity in BALF (elastase and cathepsin

35 this 24-week trial, reduction of neutrophil serine protease activity with brensocatib in patients wi

36 equires, in addition to p38 MAPK and PI3K, a serine protease activity, whereby FAP-alpha is the most

37 mals had non-inflammatory CHS with increased serine protease activity.

38 melon extract (CME) as well as a commercial serine protease (Alcalase).

39 is proteolytically-activated by bloodstream serine proteases also involved in the formation of blood

40 thought to involve off-target inhibition of serine proteases, although the precise molecular details

41 The proteases were confirmed to be serine protease and metalloprotease with molecular weigh

42 with improved selectivity over other tested serine proteases and also finding compound 21m with 27 n

43 cluding the canonical rhomboid intramembrane serine proteases and also others that have lost protease

44 tions sensitized viruses to entry-activating serine proteases and conferred more rapid entry kinetics

45 a new analogue of PK105, against recombinant serine proteases and in tissue extracts from healthy mic

46 er of inflammation by restraining neutrophil serine proteases and inflammatory caspases in a genetica

47 substrate specificity of cysteine proteases, serine proteases and metalloproteinases.

48 n-proteolytic functions of membrane-anchored serine proteases and provides unexpected new data on the

49 Serine proteases and serine protease homologs form the s

50 y one per cent of human genes, and including serine proteases and thioesterases), cysteine proteases

51 ein interactions in 2 datasets of complexes, Serine-protease and BCL-2.

52 gulation factor VIIa (FVIIa), a trypsin-like serine protease, and membrane-bound tissue factor (TF) i

53 -1, ficolin-2, and ficolin-3, the associated serine proteases, and complement activation products to

54 ll-based assays, are selective against other serine proteases, and do not show relevant cytotoxicity.

55 scle progenitor cell niche, which identified serine proteases, and especially neutrophil elastase, as

56 cell-signaling analogue of endogenous blood serine protease APC, exerts vasculoprotective, neuroprot

57 The backbone dynamics of the coagulation serine protease, apo-thrombin (S195M-thrombin), were com

58 Although serine proteases are found ubiquitously in both eukaryot

59 HtrA serine proteases are highly conserved and essential ATP-

60 Since serine proteases are often sensitive to metal ions, we i

61 The FhKT1 inhibitors do not inhibit serine proteases but are potent inhibitors of parasite c

62 KT1) exhibited no inhibitory activity toward serine proteases but was a potent inhibitor of the major

63 b that specifically inhibits the CP-specific serine protease C1s to evaluate the impact of upstream C

64 f perforin and a group of lymphocyte granule serine proteases called granzymes.

65 Sensitization of mice lacking the neutrophil serine protease cathepsin G (CG)-induced hapten-reactive

66 The serine protease cathepsin G recapitulated the effects of

67 proteolytic degradation by the endolysosomal serine protease cathepsin G.

68 d selectivity over the homologous neutrophil serine protease, cathepsin G.

69 , and ELISA experiments revealed that myelin serine proteases cleave C3 to generate active fragments.

70 caseinolytic protease subunit P (ClpP) is a serine protease conserved among bacteria that is conside

71 Rhomboids are intramembrane serine proteases conserved in all kingdoms of life.

72 The germinant signal is transduced to the serine protease CspB, which processes the cortex lytic e

73 et of trypsin and trypsin-like proteins from Serine-protease dataset.

74 We conclude that serine proteases derived from commensal bacteria can dir

75 streptokinase are strictly attributed to the serine protease domain (residues 562-791) of hPg.

76 plasminogen's kringle domains, and plasmin's serine protease domain greatly contributed to the struct

77 a mutated variant of matriptase in which the serine protease domain is locked in the zymogen conforma

78 ational analysis defines a chymotrypsin-like serine protease domain that mediates SltB autoproteolysi

79 Here, we show that the serine protease domains of C1r and C1s are located at th

80 A canonical model entails a C1r2s2 with its serine protease domains tightly packed together in the c

81 Matriptase is a membrane-anchored serine protease encoded by suppression of tumorigenicity

82 broad spectrum of plasma proteins including serine protease/endopeptidase inhibitors, coagulation fa

83 CORIN is a transmembrane type II serine protease expressed in cardiomyocytes that convert

84 Proteinase 3 (PR3) is a myeloid serine protease expressed in neutrophils, monocytes, and

85 The serine protease factor B (FB) is a key node in the AP an

86 The highly specific S1 serine protease factor D (FD) plays a central role in th

87 complex of tissue factor (TF) and the plasma serine protease factor VIIa (FVIIa) mediates the initiat

88 The serine protease factor XI (FXI) is a prominent drug targ

89 The S1 serine protease family is one of the largest and most bi

90 ptase, a member of the type II transmembrane serine protease family, in APP processing.

91 atriptase, a member of the membrane-anchored serine protease family, is found to play a key role in L

92 The overexpression of the serine protease fibroblast activation protein (FAP) allo

93 The serine protease fibroblast activation protein (FAP) is o

94 ften leads to overexpression of the membrane serine protease fibroblast-activating protein (FAP).

95 m of the study was to investigate the use of serine protease from Yarrowia lipolytica yeast for reduc

96 h Temperature Requirement A (HtrA) family of serine proteases function in the periplasm to degrade da

97 Cysteine and serine proteases function via protease-activated and mas

98 diversified via natural selection promoting serine protease gene duplication, augmenting their innat

99 d VEGFD are cleaved by thrombin and plasmin, serine proteases generated during hemostasis and wound h

100 e that LOXL2 is processed extracellularly by serine proteases, generating a 65-kDa form lacking the f

101 ed with a peptide substrate specific for the serine protease granzyme B, which is produced by recipie

102 ies of regulatory B cells overexpressing the serine protease granzyme B.

103 forming protein (perforin) and pro-apoptotic serine proteases (granzymes) into the synaptic cleft.

104 virulence factors produced by EAEC, the Pic serine protease has been implicated in bacterial coloniz

105 beta-Tryptase, a homotetrameric serine protease, has four identical active sites facing

106 Serine proteases have been implicated as key drivers and

107 genes in the Jonah multigene family encoding serine proteases have been implicated in the fly antivir

108 Although trypsin-like serine proteases have flexible surface-exposed loops and

109 dulin depend on its cleavage mediated by the serine protease hepsin.

110 ylori (H. pylori) secretes the chaperone and serine protease high temperature requirement A (HtrA) th

111 The serine protease high-temperature requirement protein A1

112 mutations conferring amino acid changes in a serine protease homologous to DegP and a serine/threonin

113 ymph serine proteases (HPs) and noncatalytic serine protease homologs (SPHs) and inhibited by serpins

114 Clip domain serine protease homologs (SPHs) are positive and negativ

115 Serine proteases and serine protease homologs form the second largest gene fa

116 these conditions the activity of neutrophil serine proteases, however, was not abolished in precurso

117 nsects is mediated by a network of hemolymph serine proteases (HPs) and noncatalytic serine protease

118 eening revealed that the membrane-associated serine protease HtrA mediates selective degradation of C

119 nspeptidase (ggt), collagenase, the secreted serine protease htrA, and components of a type VI secret

120 a higher percentage of cells expressing the serine protease HtrA1.

121 ein-related peptidase 6 (KLK6) is a secreted serine protease hypothesized to promote inflammation via

122 (a cysteine protease in cancer), and Alp2 (a serine protease in aspergillosis).

123 t ( K(i) = 0.05 nM) inhibitor of the primary serine protease in fibrinolysis, plasmin.

124 llikrein-related peptidase 2 (KLK2) is a key serine protease in semen liquefaction and prostate cance

125 splays a million-fold selectivity over other serine proteases in blood, inhibits fibrinolysis in plas

126 we provide evidence for a potential role of serine proteases in CD44-mediated necroptotic death of G

127 mational flexibility of uPA and trypsin-like serine proteases in general.

128 activates granule-associated proinflammatory serine proteases in hematopoietic precursor cells.

129 detect the activities of flavivirus NS2B-NS3 serine proteases in living cells.

130 The serine proteases in saliva differ biochemically from try

131 gulate coagulation and inflammation, binding serine proteases in suicide-inhibitory complexes.

132 deficient mosquitoes showed a persistence of serine proteases in the midgut at 48 h after blood feedi

133 is driven by membrane-bound or extracellular serine proteases in the respiratory tract.

134 secretory vitamin K-dependent anticoagulant serine protease, inactivates factors Va/VIIIa.

135 d their potency against related trypsin-like serine proteases including trypsin itself could be furth

136 ansmembrane protein and inhibitor of several serine proteases, including hepatocyte growth factor act

137 ted via proteolytic cleavage by trypsin-like serine proteases, including kallikrein-5 (KLK5), or by t

138 The activity and quantity of neutrophil serine proteases, including neutrophil elastase, are inc

139 HDM-derived cysteine and serine proteases induced APOE secretion from BALF macrop

140 ta uncover a novel mechanism whereby loss of serine protease inhibition leads to lung lymphocyte accu

141 Many members of the serine protease inhibitor (serpin) family are activated

142 at secreted proteins Fibronectin 1 (FN1) and serine protease inhibitor (serpin) family E member 2 (SE

143 ogen activator inhibitor type-1 (PAI-1) is a serine protease inhibitor (serpin) implicated in numerou

144 asminogen activator inhibitor-1 (PAI-1) is a serine protease inhibitor (serpin) that regulates fibrin

145 ene that encodes the C1 inhibitor (C1INH), a serine protease inhibitor (serpin).

146 Deletion of the gene that encodes serine protease inhibitor 1 (SPI-1) of rabbitpox virus a

147 d with pathologic enzyme activation (such as serine protease inhibitor 1) have been found in familial

148 storation of the deleted C12L gene, encoding serine protease inhibitor 1, enhances replication of MVA

149 ajority of patients harbor a mutation in the serine protease inhibitor 1A (SERPINA1) gene leading to

150 The function of serine protease inhibitor 2A (Spi2A) was studied in mous

151 Genetic mutations predispose the serine protease inhibitor alpha(1)-antitrypsin to misfol

152 -c) and IgE-tp interact with polymers of the serine protease inhibitor alpha-1-antitrypsin (A1AT).

153 i2A) was studied in mouse TH2 cells, and the serine protease inhibitor B3 (SERPINB3) and SERPINB4 gen

154 ng PDAC progression, AGRN (agrin), SERPINB5 (serine protease inhibitor B5), and CSTB (cystatin B).

155 Protease nexin-1 (PN-1) is a serine protease inhibitor belonging to the serpin superf

156 A serine protease inhibitor blocked peptide and oligosacch

157 A serine protease inhibitor but not inhibitors of cysteine

158 eased the selectivity of ShPI-1, a versatile serine protease inhibitor from the sea anemone Stichodac

159 Degradation of the protective serine protease inhibitor Kazal type 1 (SPINK1) by mesot

160 Here we show that tumor-cell-expressed serine protease inhibitor Kazal type 1 (SPINK1) is a key

161 eatments of C57/BL6J-betaENaC-Tg mice with a serine protease inhibitor ONO-3403, a derivative of camo

162 alpha1-Antitrypsin is a serine protease inhibitor produced in the liver that is

163 , we observed a compensatory increase in the serine protease inhibitor Serpina3n in mouse models of M

164 Genetic ablation of serine protease inhibitor SerpinB9 (Sb9) results in the

165 nd that maspin-a noninhibitory member of the serine protease inhibitor superfamily-translocates from

166 at alpha-1 antitrypsin (AAT; Prolastin-C), a serine protease inhibitor used for the treatment of AAT

167 otease TMPRSS2, but Zhou et al. found that a serine protease inhibitor was more protective than a cat

168 ng pathway and alpha1-antitrypsin protein (a serine protease inhibitor) expression and downregulation

169 ., plasminogen activator inhibitor-1 (PAI-1; serine protease inhibitor, clade E, member 1), connectiv

170 The loss-of-function mutations of serine protease inhibitor, Kazal type 1 (SPINK1) gene ar

171 The variant is located in the gene encoding serine protease inhibitor, low levels of which are assoc

172 translational processing is inhibited by the serine protease inhibitor, phenylmethylsulfonyl fluoride

173 In addition, increased expression of a serine protease inhibitor, the hepatocyte growth factor

174 SerpinA3N, a serine protease inhibitor, was upregulated in the dorsal

175 SLPI is a secreted serine protease inhibitor, which is overexpressed in a n

176 c alpha-amylase inhibitor CM2 (Tri a 29.02), serine protease inhibitor-like allergen (Tri a 39), and

177 ioactive peptide from the alpha1-antitrypsin serine protease inhibitor.

178 Trypsin was strongly inhibited by serine protease inhibitor.

179 neutrophil apoptosis and efferocytosis in a serine-protease inhibitor-sensitive manner.

180 in inhibition, which is in contrast to other serine protease inhibitors (camostat mesylate and aproti

181 designed to determine if S-glutathionylated serine protease inhibitors (serpins) in blood could be u

182 ctor 15 (GDF15), stanniocalcin 1 (STC1), and serine protease inhibitors (SERPINs), which significantl

183 Serine protease inhibitors (SPIs) regulate protease-medi

184 A focused library of serine protease inhibitors based on diaryl phosphonate w

185 Serine protease inhibitors of the Kunitz-bovine pancreat

186 Serpins are a family of serine protease inhibitors that regulate proteases of pl

187 binding, circulating immunoglobulin complex, serine protease inhibitors, and microtubule bundle forma

188 on in the absence of the cognate Kunitz-type serine protease inhibitors, hepatocyte growth factor act

189 Serine protease inhibitors, or serpins, are paradigms fo

190 and structure similar to a larger family of serine protease inhibitors, the Bowman-Birk inhibitors.

191 dentified from a diverse library of internal serine protease inhibitors, was originally designed as a

192 ng new avenues for a systematic discovery of serine protease inhibitors.

193 cular weight proteins classically defined as serine protease inhibitors.

194 e a large and functionally diverse family of serine protease inhibitors.

195 MEDI-579 specifically inhibits serine protease interactions with PAI-1 while conserving

196 Granzyme B (GzmB) is a serine protease involved in cell-mediated cytotoxicity i

197 TMPRSS2 is an important membrane-anchored serine protease involved in human prostate cancer progre

198 pider Cupiennius salei The chymotrypsin-like serine protease is a 28-kDa heterodimer with optimum act

199 The elevated level of chymases and other serine proteases is closely related to inflammatory and

200 protease-like activity factor), a Chlamydia serine protease, is activated via proximity-induced inte

201 man beta-tryptase, a tetrameric trypsin-like serine protease, is an important mediator of allergic in

202 center loop of SERPINB1 inhibits neutrophil serine proteases, its carboxy-terminal CARD-binding moti

203 e recently identified a V. cholerae-secreted serine protease, IvaP, that is active in V. cholerae-inf

204 The serine protease kallikrein-related peptidase 7 (KLK7) is

205 Skin desquamation is facilitated by serine proteases KLK5 and KLK7, which are tightly regula

206 was dependent on coagulation factor XIIa, a serine protease known to induce cleavage of high-molecul

207 focuses on human KLK1 and KLK5, 2 of the 15 serine proteases known as the kallikrein-related peptida

208 accharide hydrolysis by 18B7, and a putative serine protease-like active site was identified in the l

209 Staphylococcus aureus-derived serine protease-like protein (Spl) D and other closely r

210 We identified staphylococcal serine protease-like proteins (Spls) as dominant IgG4-bi

211 The role of the S aureus serine protease-like proteins in the initiation of a typ

212 s implicated the involvement of two putative serine proteases, MamE and MamO, during the early stages

213 complexes with the lectin complement pathway serine proteases MASP-1 and MASP-2.

214 associated protein (MAP) and MBL associated serine protease (MASP) are scarcely investigated.

215 e serum of mannose-binding lectin-associated serine protease (MASP)-1/3(-/-) mice contains pro-FD and

216 recognition receptor complex, MBL-associated serine protease (MASP)-3/collectin-L1/K1 hetero-oligomer

217 Membrane-anchored serine proteases (MASPs) play critical roles in the deve

218 The type II transmembrane serine protease Matriptase 1 (ST14) is commonly known as

219 e autoactivation of the type 2 transmembrane serine protease matriptase and subsequent activation of

220 n IECs, and HAI-2 regulates the cell surface serine protease matriptase, a known modifier of intestin

221 A powerful hepcidin inhibitor is the serine protease matriptase-2, encoded by TMPRSS6, whose

222 mice is caused by unchecked activity of the serine protease matriptase.

223 As all chymotrypsin-like serine proteases, matriptase is synthesized as a zymogen

224 ed mannose-binding lectin-mannose-associated serine protease (MBL-MASP) functional activity in Crohn'

225 olymers in plasma protects the antibody from serine protease-mediated degradation, without affecting

226 ssed (ELANE) encoding the neutrophil granule serine protease neutrophil elastase.

227 lot, we discovered that granzyme A (GrmA), a serine protease not previously identified in human plate

228 t dengue and other flaviviruses is the viral serine protease NS2B-NS3.

229 ion proteins potently inhibit the neutrophil serine proteases (NSPs) neutrophil elastase, cathepsin-G

230 ne defenders against infection, express four serine proteases (NSPs) that play roles in the control o

231 cies, antimicrobial peptides, and neutrophil serine proteases (NSPs).

232 nhibitors against all four of the neutrophil serine proteases (NSPs).

233 ical and genetic studies reveal that HtrA, a serine protease of B. burgdorferi, controls FlaB turnove

234 ch encodes for polyserase-1, a transmembrane serine protease of poorly understood physiological funct

235 Neutrophil elastase (NE) is a serine protease of relevance in inflammatory diseases wh

236 selective towards thrombin than to the other serine proteases of the coagulation cascade.

237 were fully identified for the first time as serine proteases of the subtilase family and meiotic pro

238 The NS2B/NS3 serine proteases of the Zika and Dengue flaviviruses are

239 in hyperactivation, thereby leading to skin serine protease overexpression and disruption of skin ba

240 (MAp)44, in regulating the composition of a serine protease-pattern recognition receptor complex, MB

241 A serine protease physiologically often comes together wit

242 ssing FnBPB could be activated to the potent serine protease plasmin by staphylokinase and tissue pla

243 mplement factor D (FD), a highly specific S1 serine protease, plays a central role in the amplificati

244 cells and reduced the activity of neutrophil serine proteases polymorphonuclear (neutrophil) elastase

245 ma kallikrein-kinin system (KKS) consists of serine proteases, prekallikrein (pKal) and factor XII (F

246 d prostate cancer, and proteinase 3 (PR3), a serine protease present in inflammatory neutrophils and

247 o subtilisin-like enzymes, a large family of serine proteases primarily comprised of secreted endopep

248 glycosylphosphatidylinositol (GPI)-anchored serine protease prostasin, which is a co-factor for matr

249 The membrane-anchored serine proteases prostasin (PRSS8) and matriptase (ST14)

250 G/IKr channel was selectively cleaved by the serine protease, proteinase K (PK).

251 The serine protease PRSS8 has shown important physiological

252 Trypsin and thrombin, structurally similar serine proteases, recognize different substrates; thromb

253 A+ unfoldase (ClpX) and a pair of heptameric serine protease rings (ClpP) that unfold, translocate, a

254 Subtilisin-like serine proteases (SBTs) are extracellular proteases that

255 t addition of subtilisin (50 nm to 2 mum), a serine protease secreted by the non-pathogenic bacterium

256 m a family of nine secretory subtilisin-like serine proteases, seven of which cleave at specific basi

257 ruses (RCN) expressing Pd calnexin (CAL) and serine protease (SP), developed WNS at a lower rate (1/1

258 how that two 20E-regulated chymotrypsin-like serine proteases specifically expressed in the reproduct

259 Here, we report that a third serine protease, StmPr3, is also secreted in an Xps-depe

260 ontrolling maturation of the subtilisin-like serine protease SUB1 in exoneme secretory vesicles.

261 For Plasmodium species, subtilisin-like serine protease (SUB1) is a key mediator of egress.

262 Neutrophil elastase is a serine protease that has been implicated in the pathogen

263 t, Mycoplasma Ig protease (MIP), is a 97-kDa serine protease that is able to cleave off the VH domain

264 Chymase is a serine protease that is predominantly expressed by mast

265 T2) is a type-II transmembrane, trypsin-like serine protease that is predominantly expressed in the l

266 , encoded by TMPRSS6, is a membrane-anchored serine protease that plays a key role in suppressing hep

267 hat the L. pneumophila effector Lpg1137 is a serine protease that targets the mitochondria and their

268 tage tumors and is activated by trypsin-like serine proteases that are highly expressed or otherwise

269 ClpPs are a conserved family of serine proteases that collaborate with ATP-dependent tra

270 ition to NE, neutrophils contain three other serine proteases that could compensate if the activity o

271 ent protease A (HtrA) represents a family of serine proteases that play important roles in microbial

272 s balance is not yet defined for some of the serine proteases that serve as coagulation factors.

273 Their secretory products contain serine proteases that suppress excitability via activati

274 at our approach may also be applied to other serine proteases, thus opening new avenues for a systema

275 s by NMDA agonists (NMDA or glycine) and the serine protease tissue plasminogen activator, previously

276 -converting enzyme 2 (ACE2) receptor and the serine protease TMPRSS2 for cell entry.

277 Interestingly, overexpression of serine protease TMPRSS2 or amphotericin treatment signif

278 than on the cell surface acid pH-independent serine protease TMPRSS2, but Zhou et al. found that a se

279 We recently identified the StmPr1 and StmPr2 serine proteases to be the substrates of the Xps type II

280 on but conferred potent activity against the serine protease trypsin (Ki = 1.5 nm).

281 xceptional, however, as it also inhibits the serine protease trypsin due to replacement of the P1 Leu

282 optimize microviridin variants targeting the serine proteases trypsin and subtilisin.

283 Thymus-specific serine protease (TSSP) is expressed by thymic epithelial

284 ase is a member of the type-II transmembrane serine protease (TTSP) family and plays a crucial role i

285 The type II transmembrane serine protease (TTSP) family encompasses several protea

286 S13 is a member of the type II transmembrane serine protease (TTSP) family.

287 The type II transmembrane serine proteases (TTSPs) are a family of cell-surface pr

288 elong to the family of type II transmembrane serine proteases (TTSPs).

289 n protein (FAP) is a cell surface-associated serine protease up-regulated in the lungs of patients wi

290 The trypsin-like serine protease, urokinase-type plasminogen activator (u

291 2 depend on angiotensin-converting enzyme 2, serine protease, virus replication, and PAD-4.

292 ors has led us to question whether these two serine proteases were equal in terms of their reactivity

293 nterplay between PAR-2 and membrane-anchored serine proteases, which may co-conspire to promote tumor

294 Activation Protein (FAP) is a membrane-bound serine protease whose expression is often elevated in ac

295 ein-related peptidases (KLKs) are a group of serine proteases widely expressed in various tissues and

296 Factor D is a trypsin-like serine protease with a narrow specificity for arginine i

297 tivated protein C (APC) is a multifunctional serine protease with anticoagulant, cytoprotective, and

298 Activated protein C (APC) is a plasma serine protease with antithrombotic and cytoprotective f

299 nan-binding protein 2) is a Ca(2+)-dependent serine protease with putative roles in blood coagulation

300 Kallikreins (KLK), a family of serine proteases with a diverse array of homeostatic fun