ライフサイエンスコーパス: serine-threonine protein kinase

1 otide-binding site, leucine-rich repeat, and serine threonine protein kinase.

2 ified as casein kinase II (CKII), a cellular serine-threonine protein kinase.

3 ubiquitously expressed and highly conserved serine/threonine protein kinase.

4 2alpha (casein kinase II), a multifunctional serine/threonine protein kinase.

5 , Ku) for its activation as a robust nuclear serine/threonine protein kinase.

6 otrimeric DNA-PK complex is then active as a serine/threonine protein kinase.

7 a protein complex and is a target of the Hpo serine/threonine protein kinase.

8 PAS kinase is an evolutionarily conserved serine/threonine protein kinase.

9 ectors such as p21-activated kinase (PAK), a serine/threonine protein kinase.

10 tely 465 kDa catalytic subunit [DNA-PKcs], a serine/threonine protein kinase.

11 ntrols, in the ciliary gene NEK2, encoding a serine/threonine-protein kinase.

12 sphatase to counter the activity of multiple serine threonine protein kinases.

13 ase1 (LIMK1) is a member of a novel class of serine-threonine protein kinases.

14 activity levels of a large number (>100) of serine/threonine protein kinases.

15 ures of the protein kinase C (PKC) family of serine/threonine protein kinases.

16 road-spectrum inhibitor of both tyrosine and serine/threonine protein kinases.

17 or tyrosine kinases, Src family members, and serine/threonine protein kinases.

18 and PRK2 are two closely related AGC-family serine/threonine protein kinases.

19 s, DNA-binding transcription regulators, and serine/threonine protein kinases.

20 with its effector protein RAF proto-oncogene serine/threonine protein kinase 1 (RAF1).

21 ound that knocking down receptor-interacting serine/threonine protein kinase 1 (Ripk1) increased both

22 ath domain (TRADD), and receptor-interacting serine/threonine protein kinase 1 (RIPK1).

23 MAPK-interacting serine/threonine-protein kinase 1 (MNK1) signaling can p

24 f PTPN12 by CDK2 impaired recruitment of the serine/threonine-protein kinase 1 (PAK1) to HER2, result

25 Expression of receptor-interacting serine/threonine-protein kinase 1 (RIP1), a protein that

26 Receptor-interacting serine/threonine-protein kinase 1 (RIPK1) is a critical

27 Receptor-interacting serine/threonine-protein kinase 1 (RIPK1) is a key media

28 Receptor-interacting serine/threonine-protein kinase 1 (RIPK1) is recruited t

29 daptor proteins such as receptor-interacting serine/threonine-protein kinase 1 (RIPK1), receptor-inte

30 lethality phenotype via receptor-interacting serine/threonine-protein kinase 1 (RIPK1)-dependent and

31 c machinery lies RIPK1 (receptor-interacting serine/threonine-protein kinase 1), which acts as a mast

32 Here we identify MAP kinase-interacting serine/threonine protein kinase 1a (MNK1a) as a novel AM

33 Signaling via receptor-interacting serine/threonine protein kinase 2 (RIPK2) was essential

34 F-kappaB activation via receptor-interacting serine/threonine-protein kinase 2 (RICK or RIPK).

35 2 (NOD2) and downstream receptor-interacting serine/threonine-protein kinase 2 (RIPK2) by human cytom

36 ed NOD2, the downstream receptor-interacting serine/threonine-protein kinase 2 (RIPK2), resulting in

37 We recently identified serine/threonine protein kinase 25 (STK25) as a negative

38 ircadian clock and the cell cycle exists via serine/threonine protein kinase-29 (STK-29), the Neurosp

39 t in melanoma 2 (AIM2), receptor-interacting serine/ threonine protein kinase 3 (RIPK3), and caspase

40 p38 MAPK downstream of receptor-interacting serine/threonine protein kinase 3 (RIPK3) and destabiliz

41 The serine/threonine protein kinase 3-phosphoinositide-depen

42 ediator of necroptosis, receptor-interacting serine/threonine-protein kinase 3 (RIP3), and HMGB1.

43 otein kinase 1 (RIPK1), receptor-interacting serine/threonine-protein kinase 3 (RIPK3), TIR-domain-co

44 dence of caspase-8- and receptor-interacting serine/threonine-protein kinase 3 (RIPK3)-mediated infla

45 RNA virus that triggers receptor-interacting serine/threonine-protein kinase 3 (RIPK3)-mediated pathw

46 c plaque undergo RIPK3 (receptor-interacting serine/threonine-protein kinase 3)-MLKL (mixed lineage k

47 GATA3, OX40 ligand, and receptor-interacting serine/threonine-protein kinase 4 (RIPK4), were downregu

48 e, we demonstrated that the tumor suppressor serine/threonine-protein kinase 4 (STK4) differentially

49 rol protein 42 homolog) and the kinase Pak4 (serine/threonine-protein kinase 4).

50 eticulum (ER) kinase, is an ER transmembrane serine/threonine protein kinase activated during ER stre

51 Previous work has indicated that the serine-threonine protein kinase Akt is a general mediato

52 of cell proliferation and apoptosis through serine-threonine protein kinase AKT-beta-catenin and Win

53 Data indicate that serine/threonine protein kinase Akt (Akt) signaling coop

54 The serine/threonine protein kinase AKT (also known as PKB)

55 The serine/threonine protein kinase Akt controls a wide rang

56 The serine/threonine protein kinase Akt is a critical regula

57 Activation of the serine/threonine protein kinase Akt is a multistep proce

58 The serine/threonine protein kinase Akt is activated by vari

59 hat the La protein is a direct target of the serine/threonine protein kinase Akt on threonine 301, an

60 The serine/threonine protein kinase Akt promotes cell surviv

61 ase holoenzyme was associated with decreased serine/threonine protein kinase AKT protein levels.

62 ted kinase) inhibitor U0126, but not by AKT (serine/threonine protein kinase Akt) and PI3K (phosphati

63 Activation of the serine/threonine protein kinase Akt/PKB is a multi-step

64 due to the inhibition of phosphorylation of serine/threonine protein kinase (AKT) and its downstream

65 hosphorylation (pS(307) IRS1/total IRS1) and serine/threonine-protein kinase (AKT) phosphorylation (p

66 released IL1beta and TNFalpha in a RAC-alpha serine/threonine-protein kinase (AKT)-dependent manner.

67 al interaction partners or substrates of the serine/threonine protein kinase AKT1.

68 utually exclusive amplification of RAC-alpha serine/threonine-protein kinase (AKT1) or AKT2 and other

69 cells in vitro and in vivo by inhibiting AKT serine/threonine-protein-kinase (AKT3), ribosomal-protei

70 dicated that ubiquinone pathway and the MAPK serine-threonine protein kinase and collagens gene-famil

71 The p38alphaMAPK is a serine/threonine protein kinase and a key node in the in

72 th Warts (Wts)/large tumor suppressor (Lats) serine/threonine protein kinase and ability to upregulat

73 The yeast Atg1 serine/threonine protein kinase and its mammalian homolo

74 two Z-disc kinases (striated muscle-specific serine/threonine protein kinase and obscurin) was dramat

75 to inhibit the mammalian target of rapamycin serine/threonine protein kinase and therefore T cell cyc

76 The role of the complex of serine/threonine protein kinases and a protein phosphata

77 lts bring to light FadD32 phosphorylation by serine/threonine protein kinases and its correlation wit

78 cific phosphodiesterases, histidine kinases, serine/threonine protein kinases and protein phosphatase

79 that the native protein is phosphorylated by serine/threonine protein kinases and that this phosphory

80 ns used to infect C. elegans such as Kin1 (a serine/threonine protein kinase) and Rom2 (a Rho1 guanyl

81 eceptor type protein tyrosine phosphatase, a serine/threonine protein kinase, and a Kruppel-type zinc

82 LRRK2 encodes a serine/threonine protein kinase, and pathogenic mutation

83 e hybrid histidine protein kinase, EspA, two serine/threonine protein kinases, and a putative transpo

84 polymerase subunit 7; IIV3-044L, a putative serine/threonine protein kinase; and IIV3-080R, a protei

85 The Pim and AKT serine/threonine protein kinases are implicated as drive

86 ple members of the casein kinase I family of serine/threonine protein kinases are involved in positiv

87 a show that ELM1, and genes encoding related serine/threonine protein kinases, are required for regul

88 ins contain a penicillin-binding protein and serine/threonine protein kinase-associated (PASTA) domai

89 ve disease caused by loss of function of the serine/threonine protein kinase ATM (ataxia telangiectas

90 SS tumor cells upon the DNA damage response serine/threonine protein kinase ATR.

91 Serine/threonine protein kinases Aurora A, B, and C play

92 Activating mutations in serine-threonine protein kinase B-RAF (BRAF) are found i

93 f somatic mutations in the gene encoding the serine-threonine protein kinase B-RAF (BRAF) in the majo

94 as harbor activating (V600) mutations in the serine-threonine protein kinase B-RAF (BRAF).

95 The serine/threonine protein kinase B (PKB, also known as Ak

96 he phosphoinositide 3-kinase (PI3K) and Akt (serine/threonine protein kinase B) survival pathway in r

97 calcium/calmodulin-dependent kinase kinase, serine/threonine protein kinase B, protein kinase A, ext

98 While targeted serine/threonine-protein kinase B-Raf (BRAF) and immune

99 anisms by which some melanoma cells adapt to Serine/threonine-protein kinase B-Raf (BRAF) inhibitor t

100 Mice were treated with vehicle or combined serine/threonine-protein kinase B-Raf (BRAF) kinase inhi

101 Serine/threonine-protein kinase B-Raf inhibitor and anti

102 velopment of a novel method for the assay of serine/threonine protein kinases based on fluorescence l

103 Salt-inducible kinase 2 (SIK2) is a serine/threonine protein kinase belonging to the AMP-act

104 arbouring point mutations (Val600Glu) in the serine/threonine-protein kinase BRAF (BRAF(V600E)) depen

105 The activating mutation of the BRAF serine/threonine protein kinase (BRAF V600E) is the key

106 eterozygous variant in the gene encoding the serine/threonine-protein kinase BRSK2.

107 Both proteins are classified as serine/threonine protein kinases, but here we report tha

108 Src-family tyrosine kinase Fyn and serine-threonine protein kinase C isoform eta (PKCeta) s

109 c domain of CD86 was truncated or mutated at serine/threonine protein kinase C phosphorylation sites,

110 the delta isoform of phospholipid-dependent serine/threonine protein kinase C, which then accelerate

111 ue of Cell, report that the C2 domain of the serine/threonine protein kinase Cdelta is a phosphotyros

112 nd specifically inhibit the master regulator serine/threonine protein kinase CK2 and the wild-type/mu

113 nding sites, which are phosphorylated by the serine/threonine protein kinase, CK2.

114 Kinase2 (CK2) is an evolutionarily conserved serine/threonine protein kinase composed of two catalyti

115 pendent protein kinase (DNA-PK) complex is a serine/threonine protein kinase comprised of a 469-kDa c

116 DNA-PKcs is a serine/threonine protein kinase comprising a single poly

117 in-dependent protein kinase II (CaMKII) is a serine/threonine protein kinase critically involved in s

118 ctivates a signal relay pathway in which the serine/threonine protein kinase D (PKD) activates the NF

119 physiological function of a newly described serine/threonine protein kinase D2 (PKD2) in aspects of

120 uires activities of tyrosine kinase TYK2 and serine/threonine protein kinase D2 (PKD2), whose recruit

121 hosphorylation is carried out by the nuclear serine/threonine protein kinase DNA-PKcs and promoted by

122 ROP5 contains a conserved serine/threonine protein kinase domain that includes onl

123 phototropins, to activation of a C-terminal serine/threonine protein kinase domain, which is tightly

124 The serine-threonine protein kinase encoded by the Tpl2 prot

125 everal functions have been attributed to the serine/threonine protein kinase encoded by open reading

126 The VZV serine/threonine protein kinase encoded by ORF66 is esse

127 Here, we show that a serine/threonine protein kinase encoding gene KERNEL NUM

128 n of the mitogen-activated, proline-directed serine/threonine protein kinase ERK1.

129 Aurora A is a serine/threonine protein kinase essential for normal mit

130 The Akt serine/threonine protein kinase family is linked to main

131 ted kinase (ERK) is a prototypic member of a serine/threonine protein kinase family known as mitogen-

132 iogenesis, members of the conserved atypical serine/threonine protein kinase family, the RIO kinases

133 Although a typical two-domain serine/threonine protein kinase fold is observed, the in

134 Previous studies have implicated a family of serine/threonine protein kinases found in rhoptries (ROP

135 rphisms between the chromosomes, including a serine/threonine protein kinase gene pkn5.

136 UL13, UL44, and US6 genes encoding the UL13 serine/threonine protein kinase, glycoprotein C (gC), an

137 utations in the Drosophila gene encoding the serine-threonine protein kinase Greatwall have previousl

138 Protein kinase D (PKD), a newly described serine/threonine protein kinase, has been implicated in

139 Integrin-linked kinase (ILK), a serine/threonine protein kinase, has roles in cell signa

140 WNKs (with no lysine (K)), unique serine/threonine protein kinases, have been best studied

141 eracted with integrin-linked kinase (ILK), a serine/threonine protein kinase implicated in cancer cel

142 ypical protein kinase C (aPKC) are conserved serine/threonine protein kinases implicated in the estab

143 endent kinase II (CaMKII), a multifunctional serine/threonine protein kinase in neurons, is believed

144 The characterization of prokaryotic serine/threonine protein kinases in bacterial pathogens

145 Although there are 11 serine/threonine protein kinases in Mycobacterium tuberc

146 32)P]ATP in the presence of staurosporine (a serine/threonine protein kinase inhibitor), genistein (a

147 ated protein kinases (MAPKs) are a family of serine-threonine protein kinases involved in many cellul

148 ase (DAPK) is a calcium calmodulin-regulated serine/threonine protein kinase involved in ischemic neu

149 WNK1 [with no lysine (K)-1] is a 250-kDa serine/threonine protein kinase involved in the maintena

150 ngiectasia mutated and RAD3-related (ATR), a serine/threonine protein kinase involved in the response

151 for posttranslational regulation of the Akt serine/threonine protein kinase involving ubiquitination

152 The results indicated that the MDV US3 serine-threonine protein kinase is transiently involved

153 PKC) family of Ca(2+) and/or lipid-activated serine-threonine protein kinases is implicated in the pa

154 Monitoring the environment with serine/threonine protein kinases is critical for growth

155 terestingly, activation of the Akt family of serine/threonine protein kinases is linked to maintenanc

156 Akt2, a phosphoinositide-dependent serine-threonine protein kinase, is highly express in in

157 th related signals, including the actions of serine-threonine protein kinases, is less well defined.

158 Glycogen synthase kinase 3beta (GSK3beta), a serine/threonine protein kinase, is a key target of drug

159 Open Stomata 1 (OST1) (SnRK2.6 or SRK2E), a serine/threonine protein kinase, is a positive regulator

160 thioredoxin-fold-containing eukaryotic-like serine/threonine protein kinase, is a virulence factor i

161 Checkpoint kinase 1 (Chk1), a serine/threonine protein kinase, is centrally involved i

162 ULK1, a serine/threonine protein kinase, is essential for the in

163 ), the Drosophila Ndr (Nuclear Dbf2-related) serine/threonine protein kinase, is required for the nor

164 silon (PKC epsilon), a member of a family of serine/threonine protein kinases, is a transforming onco

165 Polo-like kinase 3 (Plk3) is a serine/threonine protein kinase known to inhibit the cel

166 VRK1 is a nuclear serine/threonine protein kinase known to play multiple r

167 estigated the functions of the Hippo pathway serine/threonine-protein kinases Lats1 and Lats2, which

168 Microtubule-associated serine/threonine-protein kinase-like (MASTL) is a mitosi

169 protein kinases (PAK)-LIM domain-containing serine/threonine protein kinases (LIMK) signaling pathwa

170 Vacuole fission is regulated by the serine/threonine protein kinase mammalian target of rapa

171 re, we demonstrate an essential role for the serine/threonine protein kinase mammalian target of rapa

172 ough the phosphoinositide-3 kinase-RAC-alpha serine/threonine-protein kinase-mechanistic target of ra

173 ization and the levels of PknA/PknB (PknA/B) serine-threonine protein kinase-mediated Wag31 phosphory

174 The PIM1 serine/threonine protein kinase mediates growth factor a

175 The ROCK-I serine/threonine protein kinase mediates the effects of

176 P21-activated kinase 1 (PAK1), a serine/threonine protein kinase, modulates many cellular

177 , MSMEG_6129 and a predicted eukaryotic like serine/threonine protein kinase, MSMEG_5437, in the intr

178 The serine/threonine protein kinases Mst1 and Mst2 can be ac

179 other proteins known to bind wild-type CCM3, serine/threonine protein kinase MST4 (MST4), sterile 20-

180 The central importance of the serine/threonine protein kinase mTOR (mammalian Target o

181 The large serine/threonine protein kinase mTOR regulates cellular

182 Serine/threonine protein kinase mTOR regulates the maint

183 Polo-like kinase 1 (Plk1), a serine/threonine protein kinase normally expressed in mi

184 MAPKAPK3 is a serine/threonine protein kinase of the p38 signaling pat

185 n a serine protease homologous to DegP and a serine/threonine protein kinase of unknown function.

186 The serine/threonine protein kinase p90-kDa ribosomal S6 kin

187 lyzed by Pak2, a member of the p21-activated serine/threonine protein kinase (Pak) family and regulat

188 ned the integrity of the CDC42-p21-activated serine/threonine protein kinases (PAK)-LIM domain-contai

189 y of histone H3.3, which is regulated by the serine/threonine protein kinase Pak2.

190 upon PASTA-domain containing eukaryotic-like serine/threonine protein kinases (PASTA-eSTK) that sense

191 -type channels are modulated by a variety of serine/threonine protein kinase pathways, which indicate

192 ic linkages, such as signaling domains (e.g. serine/threonine protein kinase), peptidoglycan-processi

193 protein kinases; however, the proto-oncogene serine/threonine protein kinase PIM1 (PIM-1) and glycoge

194 n of each individual complex, stabilizes the serine-threonine protein kinase PINK1 on the mitochondri

195 Activity of the serine-threonine protein kinase PINOID (PID) has been im

196 escence2 (bif2) encodes a co-ortholog of the serine/threonine protein kinase PINOID (PID), which regu

197 pstein-Barr virus (EBV) BGLF4 gene encodes a serine/threonine protein kinase (PK) that is expressed i

198 his study concerns one of these enzymes, the serine/threonine protein kinase PknF, that is encoded in

199 The p21-activated kinase (PAK) family of serine/threonine protein kinases plays important roles i

200 ULK1, a mammalian serine/threonine protein kinase, plays a key role in the

201 NA (dsRNA)-activated protein kinase (PKR), a serine/threonine protein kinase, plays an important role

202 inase (PAK) 2, a member of the PAK family of serine/threonine protein kinases, plays an important rol

203 ycle, in a process that is controlled by the serine/threonine protein kinase PLK4 (refs.

204 Serine/threonine-protein kinase proteins, also known as

205 eport the efficacy of the Raf proto-oncogene serine/threonine protein kinase (RAF) inhibitor, PLX8394

206 Protein kinase D (PKD) is a serine/threonine protein kinase rapidly activated by G p

207 esis that p(21)-activated kinase-1 (Pak1), a serine-threonine protein kinase regulated by Ras-related

208 Akt1, a serine/threonine protein kinase, regulates several key e

209 ELM1 encodes a serine/threonine protein kinase required for proper regu

210 have emphasized the importance of the active serine-threonine protein kinase rhoptry protein 18 (ROP1

211 a PDE inhibitor for heart failure, inhibits serine/threonine-protein kinase RIOK1 and other kinases.

212 amage, and elevation of receptor-interacting serine/threonine-protein kinase (RIP) 1/3 were observed

213 Receptor-interacting serine/threonine-protein kinase (RIP)-3-mediated intesti

214 ling complex containing receptor-interacting serine/threonine-protein kinase (RIPK) 1 and 3.

215 The receptor-interacting serine/threonine-protein kinases RIPK1 and RIPK3 play im

216 target Rho-associated coiled-coil containing serine/threonine protein kinase (ROCK) is amplified by s

217 Rho-associated coiled-coil containing serine/threonine protein kinases (ROCKs) have recently b

218 site (NBS) and leucine-rich repeat (LRR) or serine/threonine protein kinase (S/TPK) domains.

219 al acetaldehyde/ethanol dehydrogenase (Aad), serine/threonine protein kinase, serine/threonine protei

220 ption factor Drosophila FOXO (dFOXO) and the serine/threonine protein kinase shaggy, the fly ortholog

221 M. tuberculosis encodes several serine-threonine protein kinase signaling molecules, 2 o

222 ssion of the sucrose non-fermentable-related serine/threonine-protein kinase SNRK in glomerular endot

223 type 2C protein phosphatase (PP2C) ABI1, the serine/threonine protein kinase SnRK2.6/OST1 and the tra

224 rthologue of murine striated-muscle-specific serine/threonine protein kinase, Speg).

225 The Staphylococcus aureus serine/threonine protein kinase Stk1 (also known as PknB

226 of these scaffolds, potent inhibitors of the serine/threonine-protein kinase STK10 were synthesized.

227 include the sensor/signaling proteins of the serine/threonine protein kinase (STPK) family that have

228 Mycobacterium tuberculosis serine/threonine protein kinases (STPKs) are responsible

229 Mycobacterium tuberculosis genome encodes 11 serine/threonine protein kinases (STPKs) that are struct

230 WNKs are large serine/threonine protein kinases structurally distinct f

231 ological inhibition of either IKKbeta or the serine/threonine protein kinase TAK1 in monocytes blocke

232 The evolutionarily conserved serine/threonine protein kinase target-of-rapamycin (TOR

233 tein kinase D (PKD) family consists of three serine/threonine protein kinases termed PKD, PKD2, and P

234 The Pim protein kinases are serine threonine protein kinases that regulate important

235 irus 1 (HSV-1) US3 gene is a multifunctional serine-threonine protein kinase that can block apoptosis

236 tor-associated kinase 1 (AAK1) is a cellular serine-threonine protein kinase that functions as a key

237 rated by these stimuli converge on mTORC1, a serine-threonine protein kinase that has been termed the

238 protein-coupled receptor kinase-2 (GRK2), a serine-threonine protein kinase that induces internaliza

239 le inhibitor of Polo-like kinase 4 (Plk4), a serine-threonine protein kinase that initiates centriole

240 ogen synthase kinase (GSK)-3 is a ubiquitous serine-threonine protein kinase that participates in a m

241 ubiquitously expressed and highly conserved serine-threonine protein kinase that regulates cellular

242 LKB1 is a serine-threonine protein kinase that, when inhibited, ma

243 oil-containing kinases (ROCK1 and ROCK2) are serine-threonine protein kinases that are involved in th

244 vated kinases (Paks) are Cdc42/Rac-activated serine-threonine protein kinases that regulate several k

245 Rho kinases (ROCKs) are serine-threonine protein kinases that regulate the actin

246 e kinase 3) is a widely expressed, mammalian serine/threonine protein kinase that activates multiple

247 Protein kinase B (PknB) is a transmembrane serine/threonine protein kinase that acts as an essentia

248 an target of rapamycin is a highly conserved serine/threonine protein kinase that controls initiation

249 mTOR is a serine/threonine protein kinase that forms two functiona

250 n kinase Czeta (PKCzeta) is an intracellular serine/threonine protein kinase that has been implicated

251 MLK3 is a serine/threonine protein kinase that is a member of the

252 Akt is a serine/threonine protein kinase that is activated by a v

253 Chk1 is a serine/threonine protein kinase that is activated by a w

254 VZV) open reading frame 66 (ORF66) encodes a serine/threonine protein kinase that is not required for

255 d among the alphaherpesviruses and encodes a serine/threonine protein kinase that is not required for

256 or progression locus 2 (Tpl2) gene encodes a serine/threonine protein kinase that is overexpressed in

257 ATM is a serine/threonine protein kinase that is recruited and ac

258 DNA-PKcs is a serine/threonine protein kinase that is recruited to DSB

259 Mechanistic target of rapamycin (mTOR) is a serine/threonine protein kinase that mediates phosphoino

260 TGF)-beta-activated kinase 1 (TAK1) is a key serine/threonine protein kinase that mediates signals tr

261 sphoinositide-dependent kinase-1 (PDK1) is a serine/threonine protein kinase that phosphorylates memb

262 -terminal kinase (JNK) is a stress activated serine/threonine protein kinase that phosphorylates nume

263 tegrin-linked kinase (ILK), an intracellular serine/threonine protein kinase that plays a critical ro

264 AKT/PKB is a phosphoinositide-dependent serine/threonine protein kinase that plays a critical ro

265 TANK-binding kinase 1 (TBK1) is a serine/threonine protein kinase that plays a crucial rol

266 AKT/PKB is a serine/threonine protein kinase that plays an important

267 AMP-activated protein kinase (AMPK) is a serine/threonine protein kinase that plays an important

268 nthase kinase 3 (GSK3) is a highly conserved serine/threonine protein kinase that plays important rol

269 AMP kinase is a heterotrimeric serine/threonine protein kinase that regulates a number

270 that barren inflorescence2 (bif2) encodes a serine/threonine protein kinase that regulates auxin tra

271 grin-linked kinase (ILK) is an intracellular serine/threonine protein kinase that regulates cell adhe

272 Mammalian target of rapamycin (mTOR) is a serine/threonine protein kinase that regulates cell grow

273 WNK1 is a widely expressed serine/threonine protein kinase that regulates multiple

274 malian target of rapamycin (mTOR) protein, a serine/threonine protein kinase that regulates ribosomal

275 Rho kinase (ROCK) is a serine/threonine protein kinase that regulates the actin

276 mTOR is a highly conserved serine/threonine protein kinase that serves as a central

277 tein kinase II (CaMKII) is a multifunctional serine/threonine protein kinase that transmits calcium s

278 Cyclin-dependent kinases (CDKs) are serine/threonine protein kinases that act as key regulat

279 pha-kinases are a widely expressed family of serine/threonine protein kinases that exhibit no sequenc

280 We explored the effects of siRNA on several serine/threonine protein kinases that have been implicat

281 p21-activated protein kinases (Paks) are serine/threonine protein kinases that phosphorylate Raf-

282 The p38 MAPK is a family of serine/threonine protein kinases that play important rol

283 p21-activated kinases (PAKs) are serine/threonine protein kinases that serve as important

284 Ste20-like kinase (SLK) is a serine/threonine-protein kinase that has been implicated

285 Polo-like kinase 1 (Plk1) is a serine/threonine-protein kinase that has been implicated

286 Raf1/c-Raf is a well-characterized serine/threonine-protein kinase that links Ras family me

287 ce that the calcium and calmodulin-dependent serine/threonine protein kinase type II (CaMKII) is an i

288 Like other alphaherpesviruses, MDV encodes a serine/threonine protein kinase, U(S)3.

289 Liver kinase B1 (LKB1) is a serine/threonine protein kinase ubiquitously expressed i

290 tive pathway for mitophagy that utilizes the serine/threonine protein kinase Unc-51-like kinase 1 (Ul

291 e PKM isoforms in A549 cells lacking LKB1, a serine/threonine protein kinase upstream of AMPK, failed

292 The serine/threonine protein kinase v-AKT homologs (AKTs), a

293 ning of a human thymus cDNA library, PRP4, a serine/threonine protein kinase, was identified as a KLF

294 lthy proliferating and cancerous cells, is a serine/threonine protein kinase, well known to orchestra

295 S6K1 is a member of the AGC subfamily of serine-threonine protein kinases, whereby catalytic acti

296 ing frame 36 (ORF36) of this virus encodes a serine/threonine protein kinase, which is designated the

297 WNK (with no lysine [K]) kinases are serine-threonine protein kinases with an atypical placem

298 Different studies suggest different serine/threonine protein kinases, Ymr291w/Tda1 or Snf1,

299 The serine/threonine protein kinase YpkA is an essential vir

300 One of these effectors, the Yersinia serine/threonine protein kinase YpkA, is an essential vi