ライフサイエンスコーパス: serological

1 titude of presentations, manifestations, and serological abnormalities in patients with SLE, diagnosi

2 ENV-2/3 and ZIKV FP-VLPs to develop a novel, serological algorithm for differentiating ZIKV from DENV

3 Serological analyses showed that LAIV elicited rapid (da

4 ration standard of anti-SARS-CoV-2 S1 IgG in serological analyses.

5 Serological analysis of individuals infected with A(H1N1

6 Ab response than prototypical gp120 Core by serological analysis.

7 nd 33X2 express novel capsule types based on serological and biochemical analyses.

8 With the serological and cellular immune responses to influenza v

9 mined cryo-electron microscopy structures-at serological and endosomal pH-delineating spike recogniti

10 cows assigned to 4 groups based on previous serological and fecal test results: negative low exposur

11 Increased outbreaks in pigs and serological and genetic evidence of human infection have

12 Recent IDV outbreaks in swine along with serological and genetic evidence of IDV infection in hum

13 Advances in MRI and serological and genetic testing have greatly increased a

14 e influence of HLA-DQ genotypes in clinical, serological and histological features related to CD.

15 is critical for the development of specific serological and molecular assays that can be used to det

16 We report here on 10 years of serological and molecular data in African lions, leverag

17 alised equipment, and expensive reagents for serological and molecular diagnosis respectively.

18 sms or direct analysis of infected tissue by serological and molecular methods.

19 ssess strategies for disease detection using serological and molecular techniques, and characterize g

20 Correlation of HDI data to serological and pathological measurements was performed.

21 Despite this she achieved an excellent serological and radiological response that was maintaine

22 h require high levels of bio-containment, in serological and viral entry assays.

23 Predeparture serological and viral reverse transcription-PCR (RT-PCR)

24 In 25 sites across Peru with serological and/or molecular evidence of rabies circulat

25 e research should aim to establish clinical, serological, and imaging biomarkers to identify high-ris

26 Baseline demographic, clinical, serological, and outcomes information were collected.

27 Here, we report the GII.4-serological antibody repertoire-pre- and post-vaccinatio

28 r-level based on the direct determination of serological antibody repertoire.

29 enotyping is being used as an alternative to serological antibody-based methods to determine blood gr

30 migrant class, period of study, and type of serological antigen used.

31 Serological, antigen-specific B-cell, and interleukin 2-

32 sis antigens using a field-based multiplexed serological assay and a 132-antigen bead-based reference

33 The bead-based serological assay for quantitation of SARS-CoV-2-specifi

34 Therefore, a ZIKV- or DENV-specific serological assay is essential for the accurate diagnosi

35 her betacoronaviruses is likely to impact on serological assay specificity and interpretation.TRIAL R

36 Although there was no standout serological assay, four tests achieved more than 80% pos

37 infections using a novel, well-characterized serological assay.

38 -SARS-CoV-2 total Ig and IgG high-throughput serological assays (HTSAs) and the Abbott SARS-CoV-2 IgG

39 Robust serological assays are essential for long-term control o

40 Serological assays are not routinely used in the diagnos

41 Serological assays are of critical importance to help de

42 tep procedure for developing high throughput serological assays based on synthetic peptides.

43 nge: observed antibody responses measured in serological assays depend on multiple unobserved prior i

44 testing for detection of SARS-CoV-2 RNA, and serological assays for detection of SARS-CoV-2 specific

45 Many recently released point-of-care (PoCT) serological assays have been distributed with little pre

46 Most infections are identified by serological assays including enzyme-linked immunoassay (

47 ment and regulatory approval of a variety of serological assays indicating the presence of antibodies

48 and further monitoring of the performance of serological assays is advised.

49 sed seroprevalence estimates can occur using serological assays optimized with validation sets unrepr

50 Since the 1970s, introduction of serological assays targeting virus-specific antibodies a

51 he world, there is a need for well validated serological assays that allow the detection of viral spe

52 that may be otherwise missed by traditional serological assays that are biased towards more heavily

53 Current serological assays that detect antiviral antibodies suff

54 disease, underscoring the need for improved serological assays that produce accurate diagnostic resu

55 Development of specific serological assays to detect and differentiate ZIKV from

56 Serological assays to detect antibodies have been proven

57 , validation, and appropriate application of serological assays to detect antibodies to SARS-CoV-2 ar

58 of FP has been hampered by a lack of robust serological assays to monitor exposure to ChHV5.

59 f the bat population, there are no validated serological assays to screen bat sera for ebolavirus-spe

60 yme Linked Immunosorbent Assay (ELISA)-based serological assays to study the antibody response in COV

61 Brain CT and MRI, and serological assays were done on a child with microcephal

62 Serological assays were found to vary significantly in s

63 Performance characteristics for COVID-19 serological assays were generally lower than those repor

64 Serological assays were performed on 85 human immunodefi

65 Molecular and serological assays were used to test participants exhibi

66 n combination with findings of molecular and serological assays, can discriminate between acute and p

67 tigen SAG1, a common component of commercial serological assays, via the detection of parasite-specif

68 of performance characteristics for COVID-19 serological assays.

69 ction (HBs antigen) had to be diagnosed with serological assays.

70 atitis B surface antigen) was diagnosed with serological assays.

71 , we show highly sensitive and specific Zika serological assays.

72 mens were tested by the four FDA-cleared IgG serological assays.

73 topes and develop high performance multiplex serological assays.

74 with increased antibody responses across the serological assays.

75 thermostable, closed S trimer can be used in serological assays.

76 Serological assessments for human onchocerciasis are bas

77 ers can correct for information biases using serological assessments in a subsample of survey partici

78 estimate true vaccine coverage using nested serological assessments of immune markers.

79 We confirmed this serological association using a multiplexed immunoassay

80 of the genetic, biochemical structural, and serological bases of serotypes 35C and 42.

81 ch has been considered as the most potential serological biomarker for the detection of prostate canc

82 ciated biomarkers are three major classes of serological biomarkers with GC warning potential, joint

83 lomic) and clinical (liver enzymes and other serological biomarkers, anthropometry, measures of beta-

84 85, isolated from a vaccinee with remarkable serological breadth as measured by hemagglutinin inhibit

85 Here we comprehensively characterize serological, cellular and functional immune parameters o

86 Kinetics of serological changes agreed with those previously describ

87 However, most detection methods (molecular, serological, chemical) are logistically limited for larg

88 yping assay is a critical test to ensure the serological compatibility of a donor and an intended rec

89 performance in a simple 1-tier test for the serological confirmation of LD.

90 lts in efficient viral clearance and partial serological conversion in a chronic HBV mouse model, off

91 raminidase-inhibiting antibodies, additional serological correlates of protection from infection coul

92 ease aetiologies, poor longitudinal clinical-serological correlations and a limited immunotherapy res

93 bodies from bat sera, we assess the level of serological cross-reactivity between the virus-specific

94 ver, is particularly challenging; often only serological data are available on a subset of individual

95 ling approach highlights how cross-sectional serological data can be used to estimate epidemiological

96 e extent of cross-reactivity with CHIKV from serological data collected throughout French Guiana (N =

97 We used JEV serological data from a multicountry Asian dengue vaccin

98 NGS data in addition to limited serological data provided strong diagnostic evidence tha

99 of strain A-85/14 combined with the previous serological data show the existence of a sixteenth serov

100 Finite mixture modeling can be applied to serological data to obtain estimates of the proportion o

101 excess fraction (PEF), can be estimated from serological data using finite mixture modeling.

102 hese epidemics, comparing human and ruminant serological data with environmental and cattle-trade dat

103 ted with clinical, electrophysiological, and serological data.

104 a primary infection, even in the absence of serological data.

105 biological and epidemiological insights from serological datasets.

106 We carried out serological, demographic, and phylogenetic studies of do

107 While the serological detection of (1 3)-Beta-Glucan (BDG) can ind

108 liable and practical diagnostic tool for the serological detection of dengue in realistic application

109 ed turnaround times, and can be used for the serological detection of ZIKV infections.

110 diagnose Toxoplasma gondii infections is the serological determination of antibodies directed against

111 low assay exhibits excellent sensitivity for serological diagnosis of CPA.

112 ny diagnostic tests that are employed in the serological diagnosis of this infection.

113 The reliability of the immunosensor in serological diagnosis was verified by challenging the im

114 with multiple T. cruzi strains may influence serological diagnostic test results and disease progress

115 eria species, and they have implications for serological diagnostics based on the detection of antibo

116 l accelerate the development of vaccines and serological diagnostics for severe acute respiratory syn

117 in-like growth factors IGF-1 and IGF-2 makes serological discrimination by immunodiagnostic IGF tests

118 largest and most representative study of the serological diversity of Dichelobacter nodosus in Englan

119 ata on host ecology, molecular epidemiology, serological dynamics, and viral genetics to characterize

120 Only acquiring serological endpoints in a 10% sample and imputing the r

121 Here, we describe a serological enzyme-linked immunosorbent assay for the sc

122 An additional 133 (14.0%) patients had serological evidence for a recent arboviral infection.

123 lasmodium falciparum parasite prevalence and serological evidence for exposure.

124 consistent with congenital Zika syndrome and serological evidence for Zika virus infection.

125 Of 121 shelter workers, one had serological evidence of A(H7N2) infection, corresponding

126 reports of two novel IAVs in fruit bats and serological evidence of avian influenza virus (AIV) H9 i

127 We uncovered serological evidence of exposure to Hendra-/Nipah-relate

128 Individuals with serological evidence of higher malaria exposure were abl

129 dy levels in 31 persons with and 715 without serological evidence of mumps.

130 revealed that small mammals in the area had serological evidence of orthopoxvirus infections, sugges

131 found that >43% of infected patients had no serological evidence of prior infection.

132 We show the first serological evidence of survivors in this population (ei

133 Serological evidence suggests that CCHFV can productivel

134 This study developed a panel of serological exposure markers capable of classifying indi

135 We aimed to measure prevalence of serological exposure to P knowlesi and assess associated

136 d with advanced fibrosis, assessed using the serological FIB-4 index (odds ratio [OR], 5.92; 95% conf

137 refully interpreted using both molecular and serological findings.

138 uction of anti-parietal cell antibodies, the serological hallmark of AIG.

139 ed a unique dataset documenting longitudinal serological henipa- and filovirus dynamics in three Mada

140 orrelation between subjective complaints and serological histamine parameters in patients with suspec

141 Clinical, serological, histological and HLA-DQ genetic data were c

142 We measured serological IgG responses to eight enteropathogens (Giar

143 h-affinity antibodies required for long-term serological immunity.

144 Current serological immunoassays have inherent limitations for c

145 tudy, we compared the diagnostic accuracy of serological immunoassays that are based on various SARS-

146 Serological immunoassays that can identify protective im

147 This analysis reveals how "serological imprinting" impacts responses to influenza a

148 We observed heterogeneity in serological indices across study sites in Lake Victoria.

149 residues 17-34), which could be a potential serological marker for early ZIKV detection.

150 e identified as the most parsimonious set of serological markers able to distinguish NPC cases from c

151 een groups and correlation between clinical, serological markers and imaging findings was undertaken.

152 A panel of multiple serological markers for Lyme disease are measured using

153 Thailand and Brazil and identified candidate serological markers of exposure.

154 To identify sensitive new serological markers of Schistosoma mansoni infections, w

155 Serological markers require further optimisation.

156 iral dynamics and may delay the emergence of serological markers targeted by current HIV screening an

157 Our aim was to find reliable serological markers to predict tolerance to bee and vesp

158 immunosorbent assays (ELISAs) and correlated serological measurements with NAb activity measured usin

159 eding was not associated with differences in serological measurements.

160 pical countries has the potential to improve serological measures of protection against infection.

161 At the community level, serological measures of transmission aligned with stool-

162 We compared serological measures of transmission based on antibody r

163 ased measures of infection (rho = 0.94), and serological measures provided more resolution for betwee

164 ive with >=1 henipavirus glycoprotein by >=1 serological method, and 6 serum samples were reactive ag

165 detected with a combination of molecular and serological methods, though cell culture and antigen det

166 identify the most informative age groups for serological monitoring and investigate the discriminator

167 sess (1) the most informative age groups for serological monitoring using receiver operating characte

168 insight into one of the few well-replicated serological observations in major mental illness.

169 Standard typing procedures use serological or amplification-based assays performed sequ

170 Serological parameters and clinical data were collected

171 ur objective was to identify virological and serological predictors of anal high-grade squamous intra

172 The primary outcome was serological pregnancy defined by a positive beta human c

173 Serological prevalence estimates were several times high

174 ey transplant recipients and performed virus serological profiling at day 0 and day +365, using VirSc

175 Deep serological profiling of 232 coronavirus disease 2019 (C

176 The high-throughput serological profiling of patients with COVID-19 allows f

177 We performed serological profiling of the viral infection history in

178 y in KD patients, we performed comprehensive serological profiling using a high-throughput phage immu

179 l isolates to assess the uniformity of their serological reactions.

180 er, this risk, depending on the baseline CMV serological recipient/donor status, is still controversi

181 rituximab who achieved complete clinical and serological remission.

182 ntification of IgA in subjects with a strong serological response and in the early stage of COVID-19

183 This serological response is compatible with acute, resolved,

184 er, these findings increase the knowledge on serological response to distinct PvCSP allelic variants

185 We investigated the human serological response to GAS impetigo in Fijian schoolchi

186 vations provide important information on the serological response to SARS-CoV-2 of hospitalized patie

187 and ELISA reflects different aspects of the serological response.

188 -19 cohorts, indicating a reduced protective serological response.

189 Serological responses (Seroresponse) and durability of h

190 by antigen or necropsy, indicating transient serological responses and natural resolution of infectio

191 s (HuNoV), and their vaccines elicit complex serological responses associated with previous exposure.

192 has not yet been possible to induce adequate serological responses by vaccination.

193 ugh the influenza vaccine is able to achieve serological responses in some allogeneic hematopoietic s

194 terium tuberculosis antigens associated with serological responses in tuberculosis patients.

195 abbits and rhesus macaques with RC1 elicited serological responses that targeted the V3-glycan patch.

196 In trying to account for differences in the serological responses to ChHV5 between green turtles fro

197 The primary outcome of interest was serological responses to measles vaccine, stratified by

198 To monitor the bait uptake and the serological responses to vaccination, foxes were shot by

199 Serological responses were also evaluated to assess the

200 hronic immunization induced antigen-specific serological responses with diverse SHM-mediated antibody

201 ccine is highly effective and induces robust serological responses.

202 nal allograft biopsy specimens confirmed the serological results.

203 or studies reporting HIV incidence data from serological samples collected among females aged 15-24 y

204 ive prior to the boat's departure in initial serological screening and also had neutralizing and spik

205 data demonstrate that antigens identified by serological screening are targets of multifunctional cel

206 The use of OF serological screening for HTLV-1/2 infection could facil

207 Here we report serological screening of blood or fecal samples from mon

208 Obtaining venous blood for serological screening, typically performed using enzyme

209 ecisions for migrants and support the use of serological screening, which is more sensitive and easie

210 In contrast to PCR, serological sensitivity increased with days post symptom

211 Serological sequelae of infant C. difficile colonization

212 of clinical data and respiratory, blood, and serological specimens for pathogen detection.

213 disease may include information on multiple serological states - naivete, recent infection, non-rece

214 samples were taken every 6 months to measure serological status and infection by ELISA.

215 reening of donors and recipients is based on serological status and limited to certain viruses.

216 f MOG-IgG through a longitudinal analysis of serological status over a 2-year follow-up period.

217 ted within a limited time window, as seen in serological studies and the analysis of many murine mono

218 Longitudinal serological studies are urgently needed to determine the

219 Serological studies are vital to assess neutralising ant

220 The biological, chemical, and serological studies of the recently emerged SARS-CoV-2 w

221 We propose that a major extension of serological studies to directly characterize measles sus

222 The phenotype (including histopathology and serological studies) was recorded at 3, 6, 9 and 12 mont

223 ics, ethnicity, cardiovascular risk factors, serological studies, socioeconomic status, left ventricu

224 We used serological study data from 46 geographical sites in 13

225 We conducted a serological study to define correlates of immunity again

226 h Polynesia which closely matches a previous serological study; 20.8% (95% CI: 1.1-50.0%) in Colombia

227 tline diagnostics and facilitate large-scale serological surveillance and postvaccination monitoring.

228 Through multiple years of virological and serological surveillance in a single order-buyer cattle

229 Yet recent serological survey data indicate a more sustained persis

230 Similar to a serological survey in 2011, we followed population-level

231 Here, we complete a large serological survey to elucidate the specificity of antib

232 We conducted a serological survey using a novel approach to rule out cr

233 model comparison highlights key data gaps in serological surveys across the African endemic region.

234 Serological surveys are a valuable tool to assess the ex

235 We compared results from eight serological surveys before and after known ZIKV outbreak

236 nostics, and for the mathematical models and serological surveys that underpin public health policies

237 ias information obtained via population-wide serological surveys to estimate real-time circulating, p

238 viral infection is commonly performed using serological techniques like the enzyme-linked immunosorb

239 had clinical symptoms and either a positive serological test or a known epidemiological link to a co

240 rotection, including the correlation between serological test results and risk of reinfection.

241 eved using standardized and widely available serological test systems.

242 is assessed based on changes over months in serological test titres.

243 nd on serology (any titre) or had a positive serological test with high titres, irrespective of the r

244 test for microbial diagnosis, with directed serological testing (i.e., Q fever serology, Bartonella

245 n (RPR) test with that of the combination of serological testing and an experimental 23S rRNA Trepone

246 ant implications when considering widespread serological testing and antibody protection against rein

247 cilitate coronavirus disease 2019 (COVID-19) serological testing and antiviral screening.

248 Mathematical models demonstrate that a serological testing and treatment strategy could reduce

249 The present model highlights the value of serological testing as part of intervention strategies,

250 avirus 2 infection confirmed by molecular or serological testing before randomisation (ie, modified I

251 Serological testing confirmed an infection with Entamoeb

252 at, during established disease, more regular serological testing could illuminate changes relevant to

253 rvey participants were randomly enrolled for serological testing for anti-measles virus immunoglobuli

254 Serological testing for antibodies to Ct antigens is pot

255 The optimal algorithm for implementing serological testing for COVID-19 remains to be determine

256 could serve as a noninvasive alternative to serological testing for monitoring of SARS-CoV-2 infecti

257 Serological testing for nasopharyngeal carcinoma (NPC) h

258 res careful review of medications taken, and serological testing for possible viral exposure.

259 Combining mucosal TMA testing and serological testing may increase the sensitivity of syph

260 Relying on routine virological and serological testing may not identify exposed children, w

261 del accurately estimate VES and only require serological testing of participants once, while a Cox mo

262 help reduce the sample collection burden of serological testing on both health care systems and indi

263 Detection of the ZIKV is based on serological testing that often shows cross-reactivity wi

264 ptive diagnoses, and performed molecular and serological testing to confirm DENV, CHIKV, ZIKV, or non

265 Given the limited availability of serological testing to date, the seroprevalence of SARS-

266 and March 2020 and necessitating the use of serological testing to determine past infections.

267 Serological testing to evaluate antigen-specific antibod

268 We compared the sensitivity of syphilis serological testing using the rapid plasma reagin (RPR)

269 lymerase chain reaction (RT-PCR) analysis or serological testing was used to confirm Ebola virus infe

270 expect that the availability of high-quality serological testing will be a key tool in the fight agai

271 ggest that the inclusion of both S1 and N in serological testing would capture as many potential SARS

272 boratory testing, including antigen testing, serological testing, and PCR-based assays.

273 ease status, the role of viral screening and serological testing, return-to-work considerations for e

274 ion neutralizing assay, the gold standard of serological testing.

275 If the serological tests are positive, it only proves that expo

276 However, only serological tests can determine blood provenance.

277 Serological tests exist but cannot distinguish active VL

278 Appropriate use and interpretation of serological tests for assessments of severe acute respir

279 To date, the vast majority of the serological tests for SARS-CoV-2-specific Abs are based

280 ap to guide the choice and interpretation of serological tests for SARS-CoV-2.

281 /or conducting epidemiologically appropriate serological tests for zoonotic infections, including tha

282 cientific uncertainties regarding the use of serological tests to assure immune status and a public h

283 stations and difficulty in interpretation of serological tests used to confirm diagnosis and evaluate

284 miological intervention model that leverages serological tests(6,7) to identify and deploy recovered

285 ed using a combination of clinical features, serological tests, and histopathological findings.

286 Ag in infected patients that can be used in serological tests, and its detection in saliva could be

287 difference was not explained by frequency of serological tests.

288 he usual diagnosis of this disease relies on serological tests.

289 ires positive results from two different IgG serological tests.

290 cant increase to the pre-test probability of serological tests.

291 gs add weight to negative microbiological or serological tests.

292 n, and benchmarking immunogenicity against a serological threshold associated with risk reduction of

293 In the absence of a well-defined protective serological threshold, PRNT provides complementary infor

294 on positive predictive values for different serological thresholds.

295 ost literature on suids has focused on using serological tools, with few studies investigating the us

296 Active immunization resulted in higher serological total IgG, IgG1, and IgG2a anti-alpha-syn le

297 al advantages over the traditional method of serological typing.

298 nto analyses based on partially observed HIV serological values.

299 The concentrations of HBV serological/virological biomarkers (HBV DNA, HBsAg, HBcr

300 Concentrations of HBV serological/virological biomarkers (HBV DNA, HBsAg, HBcr