ライフサイエンスコーパス: serotonergic neuron

1 and two neuronal subtypes (dopaminergic and serotonergic neurons).

2 1B heteroreceptors (receptors located on non-serotonergic neurons).

3 stry for tryptophan hydroxylase (a marker of serotonergic neurones).

4 raphe, which contains different subtypes of serotonergic neurons.

5 rfascicular dorsal raphe, both areas rich in serotonergic neurons.

6 rgic, glutamatergic and, at lower frequency, serotonergic neurons.

7 se line to permit translational profiling of serotonergic neurons.

8 pletion and could not be restored by grafted serotonergic neurons.

9 ion of neurons in the adult brain, including serotonergic neurons.

10 (SERT, SLC6A4) to the synaptic terminals of serotonergic neurons.

11 c excision of p38alpha MAPK selectively from serotonergic neurons.

12 e largely not direct postsynaptic targets of serotonergic neurons.

13 relatively homogenous DA population with few serotonergic neurons.

14 it reduces serotonin synthesis and firing of serotonergic neurons.

15 ) from the synaptic cleft after release from serotonergic neurons.

16 s that distinguish physiological subtypes of serotonergic neurons.

17 ound within brainstem areas known to contain serotonergic neurons.

18 ionary changes in the number and presence of serotonergic neurons.

19 behavior of immunohistochemically identified serotonergic neurons.

20 can substitute for the role of OCR-2 only in serotonergic neurons.

21 in 2 has selective actions on a subset of DR serotonergic neurons.

22 of both channel genes affects other types of serotonergic neurons.

23 thelium, but is excluded from the nucleus of serotonergic neurons.

24 ior segment of the eye, and dopaminergic and serotonergic neurons.

25 of optogenetic tools for precise control of serotonergic neurons.

26 ncy by controlling the rate of firing of the serotonergic neurons.

27 rom a developmental abnormality of medullary serotonergic neurons.

28 uded expansive proliferative populations and serotonergic neurons.

29 h is the only Pcdhalpha isoform expressed in serotonergic neurons.

30 crossed with Tph2-Cre mice expressing Cre in serotonergic neurons.

31 ned place aversion to pain via inhibition of serotonergic neurons.

32 a branch specific for the differentiation of serotonergic neurons.

33 ption factors to successfully generate human serotonergic neurons.

34 partial agonist displayed an effect only in serotonergic neurons.

35 ague-Dawley rat to measure the activation of serotonergic neurons: (1) determination ex vivo of accum

36 In conclusion, RO serotonergic neurons activate breathing frequency and am

37 licited by direct optogenetic stimulation of serotonergic neurons activates HSF1 and upregulates mole

38 During noxious stimuli, serotonergic neurons activation was due to a suppression

39 We found three main features of serotonergic neuron activity: (1) a large fraction of se

40 of Caenorhabditis elegans tph-1 in a pair of serotonergic neurons ADF during an aversive experience w

41 In mice harboring Di-expressing serotonergic neurons, administration of the ligand cloza

42 Consequently, excitation of serotonergic neurons alone can suppress protein misfoldi

43 c excision of KOR from dopaminergic, but not serotonergic neurons, also blocked KOR-mediated disrupti

44 nduced tagged-5-HT(1A)R endocytosis in raphe serotonergic neurons and a portion of hippocampal neuron

45 xpressed in muscles that are postsynaptic to serotonergic neurons and are known to be required for th

46 mer's disease subjects showed markedly fewer serotonergic neurons and associated higher levels of neu

47 al failure of laterally located dorsal raphe serotonergic neurons and changes in serotonergic innerva

48 (3)ARs are coexpressed with SERT in midbrain serotonergic neurons and form a physical complex in A(3)

49 TN neurons are also activated by inputs from serotonergic neurons and hypothalamic neurons.

50 drives the differentiation of beta-cells and serotonergic neurons and imparts the shared ability to p

51 Furthermore, mutants lacking serotonergic neurons and mutants that cannot synthesize

52 ysiological changes were driven by a loss of serotonergic neurons and reduced output as measured by h

53 h the diacetyl odor, FLP-34 is released from serotonergic neurons and signals through its evolutionar

54 oping mouse and chick neural tube, hindbrain serotonergic neurons and spinal glutamatergic V3 interne

55 ed facial motoneurons, catecholaminergic and serotonergic neurons and the ventral respiratory column

56 ntimate coordination between the activity of serotonergic neurons and their target cortical circuits.

57 ure, HA-5-HT(1B) receptors were expressed in serotonergic neurons and translocated to the forebrain.

58 r and physiological properties of an enteric serotonergic neuron, and adaptive feeding behaviors, yie

59 was used to quantify total enteric neurons, serotonergic neurons, and 5-HT-dependent subsets of neur

60 xpressed in the ADF neurons but not in other serotonergic neurons, and act cell-autonomously to regul

61 nd eg: robo2/3 mutants lose Eg expression in serotonergic neurons, and robo2 and eg interact genetica

62 n the neocortex, modulatory dopaminergic and serotonergic neurons, and the striatal neurons that form

63 ockout mice (Lmx1bf/f/p), which lack central serotonergic neurons, and we report that opioid analgesi

64 s loss is specific to the HSN class as other serotonergic neurons appear to differentiate normally in

65 in states, and many of the known features of serotonergic neurons appear to match this function.

66 ventral midbrain where a relevant number of serotonergic neurons are generated.

67 Contacts of Kenyon cells with serotonergic neurons are heterogeneously distributed ove

68 Serotonergic neurons are ideally situated for sensing ar

69 gorously activated by CO(2) in vivo, whereas serotonergic neurons are not.

70 In Aplysia, serotonergic neurons are widely activated during sensiti

71 Our study revealed the cilium structure of serotonergic neurons as a trigger of regulated serotonin

72 ole in assessing the contribution of RTN and serotonergic neurons as well as glial cells to respirati

73 of putative chemosensitive glutamatergic and serotonergic neurons as well as marked astrocytic gliosi

74 The heterogeneity of serotonergic neuron behavior can also help to explain th

75 ute to the respiratory stimulation caused by serotonergic neurons, but serotonin seems without effect

76 erminal neuronal identity in four classes of serotonergic neurons, but that the development of the AD

77 %) incorporated into approximately 50% of RO serotonergic neurons by injecting AAV2 DIO ChR2-mCherry

78 promoter-driven excision of p38alpha MAPK in serotonergic neurons (by Slc6a4-Cre or ePet1-Cre) or ast

79 so demonstrate that changes in the number of serotonergic neurons change larval swimming behavior.

80 Thus, although serotonergic neurons comprise a minority of RVM neurons

81 ifferentiated in vitro into dopaminergic and serotonergic neurons, contractile cardiomyocyte-like cel

82 it is unclear whether and how alterations in serotonergic neurons contribute to SSRI resistance in th

83 nucleus tractus solitarius (NTS) and caudal serotonergic neurons control the excitability of PBN neu

84 The spontaneous activity of serotonergic neurons correlates with dwelling behavior,

85 These effects of caudal MR serotonergic neurons could be at a chemoreceptor site, e

86 le counterparts proliferate and give rise to serotonergic neurons crucial for adult mating behaviour.

87 Serotonergic neurons derived from former rhombomere 2 dr

88 Genome-wide analyses of human serotonergic neurons, developing mouse brain and culture

89 and roundabout3 (robo2/3) are necessary for serotonergic neuron differentiation and function indepen

90 f Robo2/3 is part of a signal that regulates serotonergic neuron differentiation and is transduced by

91 ctions, little is known about the process of serotonergic neuron differentiation.

92 tocadherin alpha (Pcdhalpha) gene cluster in serotonergic neurons disrupts local axonal tiling and gl

93 We recently showed that acute inhibition of serotonergic neurons en masse blunts the CO(2) chemorefl

94 populations, we applied RC::PFtox to silence serotonergic neurons, en masse or a subset defined combi

95 ation of autonomic function, we transplanted serotonergic neuron enriched embryonic raphe nucleus-der

96 Here we report that a serotonergic neuron evokes two distinct neuromodulatory

97 NR patient-derived serotonergic neurons exhibited altered neurite growth an

98 As a group, presumed serotonergic neurons exhibited low tonic discharge rates

99 throughout the DR, and the vast majority of serotonergic neurons expressed both receptors.

100 Serotonergic neurons extended considerably longer neurit

101 scription factors GATA2 and GATA3 operate as serotonergic neuron fate selectors and regulate the diff

102 hila melanogaster, activation of a subset of serotonergic neurons fragments sleep without major chang

103 the efficient generation of functional human serotonergic neurons from human fibroblasts as a novel t

104 and NGN2 directly and efficiently generated serotonergic neurons from human fibroblasts.

105 ver 800 MDD patients, we generated iPSCs and serotonergic neurons from three extreme SSRI-remitters (

106 , noradrenergic neurons cease discharge, and serotonergic neurons greatly reduce activity.

107 he i5HT neurons expressed markers for mature serotonergic neurons, had Ca(2+)-dependent 5HT release a

108 precise circuit connectivity that regulates serotonergic neurons has not been well defined.

109 Serotonergic neurons have a powerful stimulatory effect

110 Central serotonergic neurons have been implicated in numerous an

111 y programs that control the specification of serotonergic neurons have been investigated by genetic m

112 The dorsal raphe (DR) serotonergic neurons have long been implicated in the pr

113 provide a comprehensive map of the inputs to serotonergic neurons, highlighting the complexity and di

114 enteric nervous systems, SERT is located in serotonergic neurons; however, these neurons are not pre

115 ponded to 5-HT in a manner characteristic of serotonergic neurons (i.e., with activation of an inward

116 reased c-Fos expression in subpopulations of serotonergic neurons identified by either tryptophan hyd

117 RO serotonergic neurons, identified by their entrainment to

118 te to the dysregulation of noradrenergic and serotonergic neurons implicated in the pathogenesis of M

119 ine the wiring logic of a broadly projecting serotonergic neuron in the olfactory system of Drosophil

120 Serotonergic neurones in the mammalian medullary raphe r

121 t of the DR) was lost, whereas the number of serotonergic neurons in a medial subpopulation (dorsal r

122 directs a subset of these cells to generate serotonergic neurons in a particular location is unresol

123 eurons during development and maintenance of serotonergic neurons in adults.

124 selectively stimulating raphe obscurus (RO) serotonergic neurons in anesthetized mice and to test wh

125 as been observing the activity of identified serotonergic neurons in animals engaged in behavioral ta

126 han hydroxylase, we found that a majority of serotonergic neurons in both dorsal and caudal raphe cel

127 terogeneity within the MR of the function of serotonergic neurons in breathing.

128 vironment and underscores neuroplasticity of serotonergic neurons in C. elegans under stress and stre

129 f the two molecules was confirmed in primary serotonergic neurons in culture.

130 tudies have examined pathological changes in serotonergic neurons in depression, particularly in elde

131 the pathophysiological role of dorsal raphe serotonergic neurons in different species and the role o

132 duced KOR-mediated GIRK currents recorded in serotonergic neurons in DRN postsynaptically, without si

133 To query brain serotonergic neurons in homeostasis, we used a neuronal

134 le of efficient and specific transduction of serotonergic neurons in mice and rats for elucidation of

135 c and noradrenergic neurons or PET1-positive serotonergic neurons in mice decreased corresponding neu

136 istry, we found changes in the activation of serotonergic neurons in the brainstem as well as evidenc

137 itch sensation, whereas mice lacking 5-HT or serotonergic neurons in the brainstem exhibit markedly r

138 Serotonergic neurons in the brainstem raphe nuclei dense

139 e present study examines the distribution of serotonergic neurons in the caudal raphe involved in the

140 Serotonergic neurons in the dorsal raphe (DR) nucleus ar

141 e neuronal density and neuritic pathology in serotonergic neurons in the dorsal raphe nuclei of elder

142 diated via the CRF type 2 (CRF2) receptor on serotonergic neurons in the dorsal raphe nucleus (DR).

143 ollable stress depend on hypersensitivity of serotonergic neurons in the dorsal raphe nucleus (DRN),

144 ors, we demonstrate that acute activation of serotonergic neurons in the dorsal raphe nucleus increas

145 Although the serotonergic neurons in the dorsal raphe project through

146 Birds also have serotonergic neurons in the dorsal raphe, suggesting tha

147 ssion within the basolateral amygdala and in serotonergic neurons in the dorsal, ventrolateral, cauda

148 e if CRF2 receptor activation has effects on serotonergic neurons in the DR in conscious behaving rat

149 Serotonergic neurons in the DRN have been theorized to e

150 ents were the predominant tonic influence on serotonergic neurons in the DRN.

151 There are approximately 100 serotonergic neurons in the Drosophila nervous system, a

152 ined the organization and development of its serotonergic neurons in the leopard frog.

153 Spinally-projecting serotonergic neurons in the LH have not been identified,

154 Single unit activity of presumed serotonergic neurons in the medulla [n. raphe obscurus (

155 Serotonergic neurons in the medulla are central respirat

156 Serotonergic neurons in the mesencephalic median raphe n

157 Here we show that serotonergic neurons in the midbrain of rats are also hi

158 Serotonergic neurons in the MnR were destroyed by the di

159 ic afferents had a strong tonic influence on serotonergic neurons in the MRN.

160 There was a severe depletion of serotonergic neurons in the nucleus raphe magnus, raphe

161 Serotonergic neurons in the raphe nuclei associated with

162 le, randomly presented sound pulses activate serotonergic neurons in the rat median raphe but not dor

163 suggesting that the LH innervates brainstem serotonergic neurons in the rostral ventromedial medulla

164 This removes the tonic inhibition of GABA on serotonergic neurons in the RVM, and activation of these

165 glutamatergic neurons in the spinal cord and serotonergic neurons in the RVM.

166 d a specific projection from NPVF neurons to serotonergic neurons in the ventral raphe nucleus (vRN).

167 sed the firing frequency of dopaminergic and serotonergic neurons in the ventral tegmental area and t

168 ty of cell types, including dopaminergic and serotonergic neurons in vitro and germ cells in vivo.

169 Phox2b was not detected in serotonergic neurons, in the A5, A6, and A7 noradrenergi

170 d laser photostimulation of ChR2-transfected serotonergic neurons increased respiratory frequency (fR

171 both short- and long-term activation of DRN serotonergic neurons induce antidepressant-like behavior

172 erm activation of dorsal raphe nucleus (DRN) serotonergic neurons induces robust behavioral responses

173 neurons in the RVM, and activation of these serotonergic neurons inhibits pain.

174 ls within RTN confirmed that lower medullary serotonergic neurons innervate RTN.

175 electrophysiology in Drosophila to show that serotonergic neurons innervating the first olfactory rel

176 e effectiveness of transplanting early-stage serotonergic neurons into the spinal cord for cardiovasc

177 expression and regulation of these genes in serotonergic neurons invites speculation that they may m

178 e immune system on a specific group of brain serotonergic neurons involved in the pathophysiology of

179 ter example: the neuromodulatory effect of a serotonergic neuron is dependent on the interval between

180 olution understanding of the connectivity of serotonergic neurons is currently lacking.

181 g of the synaptic connectivity of individual serotonergic neurons is lacking.

182 neurons, but that the development of the ADF serotonergic neurons is regulated by an UNC-86-independe

183 Induced serotonergic neurons (iSNs) showed increased expression

184 Using the serotonergic neuron-like CA77 cell line, we have demonst

185 Chemosensitive glutamatergic and serotonergic neurons located just beneath the ventral me

186 es have suggested that activation of KORs on serotonergic neurons may be sufficient to mediate aversi

187 Depletion of serotonergic neurons may contribute to impaired control

188 Here we show for the first time that serotonergic neurons migrate by somal translocation medi

189 gic neuron activity: (1) a large fraction of serotonergic neurons modulated their tonic firing rates

190 esults suggest that intrinsic differences in serotonergic neuron morphology and the resulting circuit

191 er the DeltapH(i)/DeltapH(o) of 0.75 for non-serotonergic neurones (most of which are not chemosensit

192 Serotonergic neurons not activated by hemorrhage were lo

193 We show that the C. elegans serotonergic neuron NSM acts as an enteric sensory neuro

194 assium transient current I(A) for a presumed serotonergic neuron of the rat dorsal raphe nucleus (DRN

195 Thus, the serotonergic neurones of the developing midline raphe sy

196 Serotonergic neurones of the raphenucleus and the trochl

197 The serotonergic neurons of the dorsal raphe (DR) nucleus in

198 These findings reveal that serotonergic neurons of the dorsal raphe have a state-de

199 duced p38alpha MAPK signaling cascade within serotonergic neurons of the dorsal raphe nucleus that me

200 ty after flow revealed increased activity in serotonergic neurons of the dorsal raphe.

201 Serotonergic neurons of the DRN are involved in the cont

202 We conclude that MCH reduces the activity of serotonergic neurons of the DRN.

203 We have previously shown that serotonergic neurons of the medulla are strongly stimula

204 The serotonergic neurons of the ML, though known to be activ

205 ity is initiated by a driver population, the serotonergic neurons of the nascent raphe.

206 ic neurons of the A7 and A5 cell groups, and serotonergic neurons of the nucleus raphe magnus (NRM).

207 gered internalization of tagged 5-HT(1A)R in serotonergic neurons only.

208 The study found no evidence of a loss of serotonergic neurons or of neuritic pathology in the dor

209 nd saporin (anti-SERT-SAP; 1 microm) to kill serotonergic neurones, or (c) SP-SAP and anti-SERT-SAP t

210 the larva forms an anterior concentration of serotonergic neurons, or apical organ.

211 As in serotonergic neurons, Pet1 expression in islets required

212 Serotonergic neurons possess an enhanced ability to rege

213 In this study we show that the output of serotonergic neurons, possibly through points of synapti

214 We propose that DR serotonergic neurons preempt reward delays at the decisi

215 DRN serotonergic neurons project broadly throughout the brai

216 Serotonergic neurons project their axons pervasively thr

217 Serotonergic neurons project widely throughout the brain

218 Serotonergic neurons project widely throughout the CNS a

219 n neuronal than EC cell serotonin; moreover, serotonergic neurons promote development/survival of som

220 ency, inactivation of the leptin receptor in serotonergic neurons recapitulates them fully.

221 This work establishes that serotonergic neurons regulate life-sustaining respirator

222 1877-1893), who show that serotonergic neurons regulate the growth of peripheral t

223 r, the subsequent differentiation of central serotonergic neurons required both the suppression of VM

224 Restoring NS3 to only 106 serotonergic neurons rescued global growth defects.

225 -like episodes correlated with the number of serotonergic neurons restored with orexin receptor expre

226 saicin-induced activation of dopaminergic or serotonergic neurons reversibly alters both physiologica

227 Here we show that network-spanning serotonergic neurons segregate information about stimulu

228 In Drosophila, a small group of serotonergic neurons selectively modulates the escalatio

229 n the metazoan central nervous system (CNS), serotonergic neurons send projections throughout the syn

230 Electrophysiologically, female serotonergic neurons showed blunted membrane excitabilit

231 BS-NSC graft-derived catecholaminergic and serotonergic neurons showed remarkable long-distance axo

232 These results suggest that serotonergic neurons signal information about reward and

233 Transgenic mouse serotonergic neurons specifically labeled by enhanced ye

234 cular and anatomical properties, including a serotonergic neuron subtype that preferentially innervat

235 mportance of ZFPM1 for the development of DR serotonergic neuron subtypes involved in mood regulation

236 electors and regulate the differentiation of serotonergic neuron subtypes of DR.

237 d at least 18 distinct neuron subtypes and 5 serotonergic neuron subtypes with distinct molecular and

238 -Fos expression was greatly increased in DRN serotonergic neurons suggesting that OFF DRN-projecting

239 Its differential occurrence in serotonergic neurons supports the idea that 5-HT(1A)R in

240 s exclusion from GABAergic, cholinergic, and serotonergic neurons supports the notion that DNPI/VGLUT

241 dentify conserved ion channels in an enteric serotonergic neuron that mediate its responses to food i

242 pical plate and pharyngeal endoderm, and 4-6 serotonergic neurons that are confined to the apical pla

243 dicate that the BF shift can be modulated by serotonergic neurons that augment or reduce the BF shift

244 However, it remains unknown how serotonergic neurons that innervate the first olfactory

245 We examined the sole pair of serotonergic neurons that innervates the Drosophila ante

246 r the genetic inactivation of Tph2 in caudal serotonergic neurons that project to the NTS protects ag

247 ine the wiring logic of a broadly projecting serotonergic neuron (the CSDn) that spans several olfact

248 A pair of serotonergic neurons (the CSDns) innervate the antennal

249 ns, egg laying, which is driven by a pair of serotonergic neurons, the hermaphrodite-specific neurons

250 To investigate afferent influences on serotonergic neurons, this study compared the role of en

251 ophila ventral nerve cord (VNC), each of two serotonergic neurons tiles distinct innervation patterns

252 odulatory actions at one synapse may allow a serotonergic neuron to play distinct roles at different

253 These SONs activate serotonergic neurons to inhibit nociceptor-to-SON transm

254 The findings suggest that NS3 acts in serotonergic neurons to regulate insulin signaling and t

255 This increased ability of serotonergic neurons to robustly grow on high amounts of

256 ), a specific marker of early differentiated serotonergic neurons, to study their migration via immun

257 amined how visceral motor neurons (VMNs) and serotonergic neurons, two neuronal subtypes, are sequent

258 ifferentiation of an embryonically generated serotonergic neuron type.

259 reproducible and accurate method to profile serotonergic neurons under a variety of conditions and s

260 of GATA cofactor ZFPM1 in the development of serotonergic neurons using Zfpm1 conditional mouse mutan

261 (Ucn 2) increases c-Fos expression in rat DR serotonergic neurons via actions on CRF2 receptors, we g

262 omically and functionally distinct subset of serotonergic neurons via activation of CRF2 receptors.

263 ession of serotonin (5-HT) in axotomized non-serotonergic neurons via HIF-1, a hypoxia-inducible tran

264 laevis larvae modulates the specification of serotonergic neurons via regulation of expression of the

265 a mitogen-activated protein kinase (MAPK) in serotonergic neurons was found to be a critical mediator

266 lla, but the number of catecholaminergic and serotonergic neurons was not significantly reduced.

267 e with Fos and markers for noradrenergic and serotonergic neurons was used to examine if an intraplan

268 raphe nucleus (RN), the major source of most serotonergic neurons, was altered in OCD patients and co

269 chniques and a novel lentiviral reporter for serotonergic neurons, we identified and overexpressed ke

270 l role of GLUA1-containing AMPA receptors in serotonergic neurons, we used the Cre-ERT2/loxP-system f

271 tro, and into mature-appearing pyramidal and serotonergic neurons weeks after being injected into the

272 in 1 receptor-positive neurons or descending serotonergic neurons were ablated before hyperalgesic pr

273 We sought to determine whether medullary serotonergic neurons were affected in multiple system at

274 Putative serotonergic and non-serotonergic neurons were distinguished from one another

275 Grasshopper serotonergic neurons were microinjected with a fluoresce

276 F DRN-projecting RGCs predominately activate serotonergic neurons whereas ON DRN-projecting RGCs main

277 o regions receive a very small input from ML serotonergic neurons which, instead, heavily innervate t

278 d that the DeltapH(i)/DeltapH(o) of 0.69 for serotonergic neurones (which are stimulated by acidosis)

279 rominent at locations that contain medullary serotonergic neurones, which are chemosensitive in vitro

280 Serotonergic neurons, which are born early from TC proge

281 We tested hypotheses that serotonergic neurons, which arise early, affect developm

282 ur study reveals the complex connectivity of serotonergic neurons, which combine the integration of l

283 in contrast to activity in noradrenergic and serotonergic neurons, which is more tightly coupled to t

284 o long-term increases in the excitability of serotonergic neurons, which may represent a mechanism un

285 lls also activate dorsal raphe nucleus (DRN) serotonergic neurons, which project to the vicinity of t

286 Pet1 neurons may act downstream of Egr2-Pet1 serotonergic neurons, which were previously established

287 ntly augmented or reduced the activity of DR serotonergic neurons, while mice decided between differe

288 Destruction of serotonergic neurons with 5,7-DHT resulted in fragmented

289 an hydroxylase 2 gene efficiently transduced serotonergic neurons with a specificity of approximately

290 Inhibition of caudal MR serotonergic neurons with the 5-HT(1A) receptor agonist

291 We 'tagged' serotonergic neurons with the light-sensitive protein ch

292 We conclude that serotonergic neurons within the caudal MR provide a non-

293 stimuli via actions on a specific subset of serotonergic neurons within the dorsal raphe nucleus.

294 topographically organized subpopulations of serotonergic neurons within the DR.

295 In this study, we use a pair of identified serotonergic neurons within the Drosophila olfactory sys

296 ation of Egr2-neurons thus may stem from non-serotonergic neurons within the Egr2 domain.

297 provide further support for the presence of serotonergic neurons within the median raphe nucleus tha

298 Furthermore, the basic branching pattern of serotonergic neurons within the neuropil remains unchang

299 ngle-cell level, the complex connectivity of serotonergic neurons within their target networks, ident

300 greater neurofibrillary pathology and fewer serotonergic neurons would be found in the dorsal raphe