ライフサイエンスコーパス: serrated adenoma

1 AF mutation were pathologically proven to be serrated adenoma.

2 ed adenomas/polyps (SSA/Ps), and traditional serrated adenomas.

3 , sessile serrated adenomas, and traditional serrated adenomas.

4 , sessile serrated adenomas, and traditional serrated adenomas.

5 so traditional serrated adenomas and sessile serrated adenomas.

6 hyperplastic polyps, adenomas, and solitary serrated adenomas.

7 indicate that the polyps in our patients are serrated adenomas.

8 ific polymerase chain reaction in 102 HPs, 8 serrated adenomas, 19 tubular adenomas, and 9 adenocarci

9 d sites was significantly higher in sporadic serrated adenomas (2.0 +/- 1.7) than in tubular adenomas

10 resected colorectal cancer, and in 70 HPs, 4 serrated adenomas, 3 admixed hyperplastic-adenomatous po

11 f HPs (P = 0.01 versus sporadic HPs), 75% of serrated adenomas, 33% of admixed hyperplastic-adenomato

12 IMP-high) was also more frequent in sporadic serrated adenomas (68%, 15 of 22) than in tubular adenom

13 We therefore evaluated CIMP in 22 sporadic serrated adenomas and 6 serrated adenomas with multiple

14 CpG island methylation is common in sporadic serrated adenomas and may play an important role in thei

15 Human sessile serrated adenomas and right-sided colorectal tumors with

16 nly hyperplastic polyps but also traditional serrated adenomas and sessile serrated adenomas.

17 Traditional serrated adenomas and SSLs are precursors to colorectal

18 and molecular characteristics of 129 HPs, 6 serrated adenomas, and 3 admixed hyperplastic-adenomatou

19 tegories of hyperplastic polyps, traditional serrated adenomas, and sessile serrated lesions (SSLs).

20 of human hyperplastic polyps (HPPs), sessile serrated adenomas, and traditional serrated adenomas.

21 ing also is activated in human HPPs, sessile serrated adenomas, and traditional serrated adenomas.

22 Serrated adenomas are characterized by a saw-toothed gro

23 In this study, SSA/Ps and traditional serrated adenomas are referred to collectively as STSAs.

24 subgroup analysis was performed for sessile serrated adenomas for 2007-2012.

25 The polyps in our patients and control serrated adenomas had a decrease or absence of endocrine

26 Patients with sporadic serrated adenomas had a higher frequency of hyperplastic

27 Sporadic serrated adenomas had significantly more frequent methyl

28 p studies, premalignant potential of sessile serrated adenomas has been described and screening utili

29 ed polyps, particularly SSLs and traditional serrated adenomas, have an increased risk of synchronous

30 pigenetic alterations in the pathogenesis of serrated adenomas is not clear.

31 al adenomatous polyposis (n = 18) or sessile serrated adenomas (n = 15) and normal colonic tissue fro

32 perplastic polyps (n = 34; 32%), traditional serrated adenomas (n = 3; 3%), sessile serrated adenomas

33 ma with low grade dysplasia, n = 27; sessile serrated adenoma, n = 4; tubulovillous adenoma with high

34 redominance of HPs in the right colon and/or serrated adenomas (P = 0.0009) and were associated with

35 rsor lesion, the proximal hyperplastic polyp-serrated adenoma pathway.

36 CRC precursor lesions (including sessile serrated adenoma/polyps (SSA/P), traditional serrated ad

37 tic polyps and potentially malignant sessile serrated adenoma/polyps.

38 ional serrated adenomas (n = 3; 3%), sessile serrated adenomas/polyps (SSA/Ps) (n = 70; 66%), unspeci

39 Sessile serrated adenomas/polyps (SSA/Ps) and traditional serrat

40 SPs comprise hyperplastic polyps, sessile serrated adenomas/polyps (SSA/Ps), and traditional serra

41 ints included conventional adenomas, sessile serrated adenomas/polyps (SSA/Ps), or colorectal cancer,

42 ue, HES1 expression is often lost in sessile serrated adenomas/polyps (SSAs/SSPs) and colorectal canc

43 gh protein expression, especially in sessile serrated adenomas/polyps and Lynch syndrome.

44 6.8%; relative risk = 2.1), and for sessile serrated adenomas/polyps than for conventional adenomas

45 body fat, tended to be stronger for sessile serrated adenomas/polyps than hyperplastic polyps.

46 human colorectal tissue samples--48 sessile serrated adenomas/polyps, 70 sporadic high-grade dysplas

47 oreover, ectopic crypts found in traditional serrated adenomas show basal LGR5 mRNA, indicating that

48 pression of GREM1 also occurs in traditional serrated adenomas, sporadic premalignant lesions with a

49 _ad), villous morphology (TVA + VA), sessile serrated adenoma (SSA) and hyperplastic polyp (HP), were

50 detailed process of progression from sessile serrated adenoma (SSA) to dysplasia and carcinoma has no

51 aditional serrated adenoma (TSA), or sessile serrated adenoma (SSA) with villous characteristics (>/=

52 Sessile serrated adenomas (SSAs) and traditional serrated adenom

53 , such as tubular adenomas (TAs) and sessile serrated adenomas (SSAs), we profiled stool samples from

54 hat contribute to the development of sessile serrated adenomas (SSAs).

55 ps in our patients were much more similar to serrated adenomas than to hyperplastic polyps and were c

56 as cancer or a tubular adenoma, traditional serrated adenoma (TSA), or sessile serrated adenoma (SSA

57 ted adenomas/polyps (SSA/Ps) and traditional serrated adenomas (TSAs) are now distinguished from hype

58 ile serrated adenomas (SSAs) and traditional serrated adenomas (TSAs) constituted 36.8% (137 of 372)

59 ed lesions (SSLs) and traditional or unknown serrated adenomas (TSAs, USAs), in Kudo type II CRLs<10

60 serrated adenoma/polyps (SSA/P), traditional serrated adenomas, tubular adenomas >/=10 mm or with hig

61 antly greater binding to tubular and sessile serrated adenomas versus hyperplastic polyps and normal

62 Sessile serrated adenomas were uncommon (n = 417, 4.5 %), with g

63 as without dysplasia, as well as traditional serrated adenoma with dysplasia.

64 All five serrated adenomas with admixed hyperplastic glands and a

65 CIMP in 22 sporadic serrated adenomas and 6 serrated adenomas with multiple (6 to 10) hyperplastic p

66 ons includes hyperplastic polyps and sessile serrated adenomas without dysplasia, as well as traditio