ライフサイエンスコーパス: serrated polyp

1 among adenomas), and obesity (P = 0.01 among serrated polyps).

2 help detect neoplastic polyps (adenomas and serrated polyps).

3 ing at least 1 hamartomatous or hyperplastic/serrated polyp.

4 h these changes contribute to development of serrated polyps.

5 mmatory factors contribute to development of serrated polyps.

6 ve 1 or more adenomas, advanced adenomas, or serrated polyps.

7 We studied CRC risks associated with serrated polyps.

8 these lesions using current terminology for serrated polyps.

9 the membrane) rapidly developed large cecal serrated polyps.

10 he intestine of mice promotes development of serrated polyps.

11 of mice promoted development of small cecal serrated polyps.

12 haracteristics, and clinical significance of serrated polyps.

13 a trend towards increased identification of serrated polyps (0.15 vs 0.07) and all neoplastic (adeno

14 om the SIR for CRC in patients with multiple serrated polyps (0.74; 95% CI, 0.20-1.90; P = .70).

15 vs 0.07) and all neoplastic (adenomatous and serrated) polyps (1.50 vs 1.14) per procedure.

16 vs 8.2%; P = .73) or clinically significant serrated polyps (10.0% vs 10.3%; P = .82) at the follow-

17 lternative definition of clinically relevant serrated polyps (12.3%; 95% CI, 9.3-15.4; P < .001).

18 polyposis: 3.28, 95% CI, 2.16-4.77; multiple serrated polyps: 2.79, 95% CI, 2.10-3.63; P = .50).

19 oxin to HBUS mice accelerated development of serrated polyps (95% of treated mice developed polyps be

20 CRC, advanced adenomas, or large (>/=10 mm) serrated polyps after 3 surveillance colonoscopies were

21 6.7 % with high-grade dysplasia (HGD), 9.6 % serrated polyps and 11.2 % adenocarcinomas.

22 y interval increases the detection of missed serrated polyps and could change the diagnosis of SPS in

23 owered for improved detection of significant serrated polyps and for longer-term follow-up to investi

24 rols, 489 cases with adenoma, 401 cases with serrated polyps, and 188 cases with both polyp types.

25 CRC begins as adenomatous or serrated polyps, and in particular as advanced precursor

26 of colorectal polyps, including adenomas and serrated polyps, and single-nucleotide polymorphisms (SN

27 colorectal polyps, conventional adenomas and serrated polyps, and their resulting CRC counterparts.

28 Human intestinal serrated polyps are a heterogeneous group of benign lesi

29 py interval colorectal cancers are proximal; serrated polyps are often precursors to these cancers an

30 gher proportion of subjects with significant serrated polyps as well as a higher total number of sign

31 tion of categories and molecular features of serrated polyps, as well as endoscopic detection and ris

32 The importance of serrated polyps, as well as their surveillance intervals

33 nfirm the functions of previously identified serrated polyp-associated molecules and indicate roles f

34 enoma, 1.47; 95% CI, 1.27-1.71), more than 3 serrated polyps at the index examination (RR=2.16, 95% C

35 ry of colorectal cancer and detection of 1-2 serrated polyps at the index examination.

36 Detection rates of significant serrated polyps between both arms were compared using th

37 ation was positively correlated with sessile serrated polyps but not with other serrated polyps (P =

38 investigated whether patients with multiple serrated polyps, but not meeting the World Health Organi

39 67 was significantly associated with sessile serrated polyps, but this association was opposite of th

40 of EGFR protein and phosphorylation in human serrated polyps by immunohistochemical and immunoblot an

41 nd 2007 and comprised 628 adenoma cases, 594 serrated polyp cases, 247 cases with both types of polyp

42 well as a higher total number of significant serrated polyps compared to standard colonoscopy (12.8%

43 Serrated polyps comprised 3.0% of all polyps and were pr

44 Development of serrated polyps depends on the composition of the gut mi

45 om WNT-driven expansion of stem cells, while serrated polyps derive from differentiated cells through

46 is 20%-40% in average-risk individuals; most serrated polyps detected are hyperplastic.

47 h elevated adenoma detection (32.3%) but not serrated polyp detection (3.2%).

48 e (ADR), and secondary outcomes were sessile serrated polyp detection rate (ssPDR), polyp detection r

49 contrast material tagging markedly improved serrated polyp detection with an odds ratio of 40.4 (95%

50 definition white light colonoscopy regarding serrated polyps' detection.

51 ed by PDGFRA(+) fibroblasts is important for serrated polyp development.

52 dicate roles for immune and stromal cells in serrated polyp development.

53 rom myeloid cells during the early stages of serrated polyp development.

54 ystem can increase detection of adenomas and serrated polyps during colonoscopy in comparison to hist

55 hlights our practice's low detection rate of serrated polyps, emphasizing the need for increased awar

56 atients with prior detection of at least one serrated polyp >=10 mm or >= 3 serrated polyps larger th

57 , and 15.6% had conventional adenomas and/or serrated polyps >/=6 mm.

58 Epidemiology studies of serrated polyps have been hampered by inconsistencies in

59 report the prevalence and characteristics of serrated polyps identified in a large, average-risk popu

60 US28) in intestinal epithelial cells develop serrated polyps in the cecum.

61 These serrated polyps include not only hyperplastic polyps but

62 ariations in rate of endoscopic detection of serrated polyps indicate the need for careful examinatio

63 at least one serrated polyp >=10 mm or >= 3 serrated polyps larger than 5 mm, both proximal to the s

64 cerous lesions (advanced adenomas or sessile serrated polyps measuring >/=1 cm in the greatest dimens

65 (n = 1,439) and 0.85 (95% CI, 0.75-0.97) for serrated polyp (n = 1,878).

66 20), tubulovillous adenoma (n = 10), sessile serrated polyps (n = 3), and invasive cancer (n = 2).

67 whether detection of proximal nondysplastic serrated polyps (ND-SP) at screening and surveillance co

68 th confirmed serrated polyposis and multiple serrated polyps (odds ratio, 1.35; 95% confidence interv

69 ing that it is also associated with multiple serrated polyps (odds ratio, 460; 95% confidence interva

70 For nonadvanced adenomas and for serrated polyps overall, only rs961253 was statistically

71 h sessile serrated polyps but not with other serrated polyps (P = 0.02).

72 detection and removal of adenomas; however, serrated polyps, particularly sessile serrated polyps (S

73 Patients with serrated polyps, particularly SSLs and traditional serra

74 (P = 0.05 among adenomas and P < 0.001 among serrated polyps), postmenopausal estrogen-only therapy (

75 d adenomatous polyps, and 5.7% had 1 or more serrated polyps removed.

76 al (NLs), 176 conventional adenomas (AD), 42 serrated polyps (SER), and 2760 CRC samples, we estimate

77 right-sided conventional adenomas (cAD) and serrated polyps (SP) compared to cecal intubation in a l

78 GROUND & AIMS: Certain subsets of colorectal serrated polyps (SP) have malignant potential.

79 Certain subsets of colorectal serrated polyps (SP) have malignant potential.

80 Serrated polyp (SPs) are precursors to 20% to 30% of cas

81 CKGROUND & AIMS: Surveillance guidelines for serrated polyps (SPs) are based on limited data on longi

82 tial localization of some neoplasms, such as serrated polyps (SPs), in specific areas of the intestin

83 Little is known about the natural history of serrated polyps (SPs), partly due to the lack of large-s

84 highest prevalence of markers was in sessile-serrated polyps (SSP) of >/=10 mm that were in the right

85 Sessile serrated polyps (SSPs) could account for a substantial p

86 wever, serrated polyps, particularly sessile serrated polyps (SSPs), are increasingly acknowledged as

87 atures of AA patients diagnosed with sessile serrated polyps (SSPs).

88 ng analysis showed subsets of fibroblasts in serrated polyps that express genes that regulate matrix

89 n of the MMP inhibitor reduced the number of serrated polyps that formed in the HBUS mice.

90 World Health Organization propose assigning serrated polyps to categories of hyperplastic polyps, tr

91 The mean age of patients with serrated polyps was 54.6 +/- 8.1 years, and there was a

92 CIs for early-onset conventional adenoma and serrated polyp were estimated with logistic regression m

93 und in the distal colon, while 80.5 % of all serrated polyps were detected in the proximal colon.

94 on varied significantly between adenomas and serrated polyps were sex (P < 0.001), use of estrogen-on

95 findings (adenoma, advanced adenoma, sessile serrated polyp) were analyzed in association with cancer

96 ffers a higher detection rate of significant serrated polyps when compared to standard colonoscopy.

97 l cancer (CRC) can arise from adenomatous or serrated polyps, which differ in their detection rate an

98 The risk of CRC in patients with multiple serrated polyps who do not meet the criteria for serrate

99 d pathological data were reviewed, comparing serrated polyps with adenomas and hyperplastic polyps in