ライフサイエンスコーパス: serum sodium

1 from those incurred by patients with normal serum sodium.

2 hyponatremia or the absolute decrease in the serum sodium.

3 , hypertension, diabetes, smoking status and serum sodium.

4 atory rate, hematocrit, platelet counts, and serum sodium.

5 year-old participants with higher middle age serum sodium.

6 Hypohydration elevates serum sodium.

7 d low ejection fraction, blood pressure, and serum sodium.

8 ingdom is now based on a model that includes serum sodium.

9 nsity lipoprotein cholesterol by 20%, raised serum sodium (0.44+/-0.14 mmol/L, P=0.02), and lowered s

10 unt <250 x 103/muL (1.92 [1.02-3.60]), lower serum sodium (1.12 [1.02-1.23 per 1 mmol/L decrease), an

11 younger age (0.83 [.74-.92] per year), lower serum sodium (1.15 [1.04-1.27] per mmol/L decrease), hig

12 ], 1.01 to 1.12); for a 2 mmol/l decrease in serum sodium, 1.22 (95% CI, 1.08 to 1.38); and for a 10

13 Serum sodium (128 +/- 4 vs. 138 +/- 1 mmol/L, p <.05) an

14 asures, except OMT patients had a lower mean serum sodium (128 mg/dl vs. 134 mg/dl; p = 0.001) and a

15 +/- 12 versus 83 +/- 14 mmHg, P = 0.009) and serum sodium (131 +/- 7 versus 135 +/- 5 mEq/L, P = 0.00

16 Middle age serum sodium above 142 mmol is a risk factor for LVH and

17 Serum sodium above 143 mmol/L was associated with 107% i

18 The mean increase in serum sodium after 24 hours was 4.9 mmol/L (95% CI, 0.5-

19 It remains unknown whether changes of serum sodium after ICU admission affect mortality, espec

20 rting enzyme inhibitors, platelet count, and serum sodium, albumin, and creatinine levels.

21 del for Endstage Liver Disease (MELD) score, serum sodium, albumin, lactulose use, rifaximin use, and

22 The absolute change in serum sodium alone is a poor predictor of clinical sympt

23 In contrast, serum sodium and bicarbonate showed associations predomi

24 Model for End-Stage Liver Disease including serum sodium and Child Pugh Scores.

25 death specific to progressive HF were SDNN, serum sodium and creatinine levels.

26 We found that, after the water load, serum sodium and free water clearance were diminished in

27 he water load resulted in a reduction of the serum sodium and free water clearance without a concomit

28 liver disease - sodium (MELDNa) incorporates serum sodium and has been shown to improve the predictiv

29 normal-to-normal RR intervals (SDNN); lower serum sodium and higher creatinine levels; higher cardio

30 viral therapy, chief complaint of fever, low serum sodium and low hemoglobin.

31 Torcetrapib raised serum sodium and lowered potassium, consistent with an a

32 The median serum sodium and MELD scores were 137 mEq/L (range, 110-

33 Lower serum sodium and more red blood cell transfusions were a

34 Contrarily, the inverse association between serum sodium and mortality no longer existed in all mult

35 with a MELD score of less than 21, only low serum sodium and persistent ascites were independent pre

36 In ambulant outpatients with chronic HF, low serum sodium and SDNN and high serum creatinine identify

37 estigated the relationship between admission serum sodium and the primary end point of days hospitali

38 administration did not significantly affect serum sodium and thrombotic events during the study peri

39 a (i.e., only 20% of patients had a baseline serum sodium), and a lack of data on the newer formulati

40 ebrospinal fluid volume, ventricular volume, serum sodium, and Glasgow Coma Scale scores were assesse

41 ology, LV systolic function, renal function, serum sodium, and PAP.

42 rence, alphafetoprotein at recurrence, donor serum sodium, and pretransplant recipient neutrophil-lym

43 Disorders of serum sodium are both the most common and probably most

44 questions: Which of the determinants of the serum sodium are deranged and what is the underlying cul

45 Listing eGFR, dialysis, and serum sodium are potent, independent predictors of 90-da

46 sociated with low serum sodium, we evaluated serum sodium as an independent predictor of mortality in

47 nate, chloride, and pulmonary disease, while serum sodium, AST and liver disease were associated with

48 Here, we evaluate the association of serum sodium at middle age as a measure of hydration hab

49 id therapy and fluid losses on the patient's serum sodium, balances potential benefits and risks, and

50 of End Stage Liver Disease score (MELD), and serum sodium based modifications like the MELD-Na score

51 emporal progression of clinical features and serum sodium, brain magnetic resonance imaging (MRI), po

52 Similarly, low serum sodium-chloride levels (< 33) correlated with high

53 in AHF (signs of cerebral hypoperfusion, low serum sodium, chronic obstructive pulmonary disease, and

54 entration <135 mmol/L and hypernatremia as a serum sodium concentration >145 mmol/L.

55 sodium concentration and with hyponatremia (serum sodium concentration < or =135 mEq/L) in 2 non-His

56 Hyponatremia was defined as a serum sodium concentration <135 mmol/L and hypernatremia

57 complications, especially if the decrease in serum sodium concentration ([Na+]) is large or rapid.

58 e patients 12 months after LT (P=0.04), with serum sodium concentration (P=0.01) predictive for graft

59 The primary outcome was serum sodium concentration after treatment.

60 A strong association between change in serum sodium concentration and change in VBR was noted a

61 olymorphism is significantly associated with serum sodium concentration and with hyponatremia (serum

62 wide study shows that the MELD score and the serum sodium concentration are important predictors of s

63 Urea increased serum sodium concentration by a mean of 9.6 mmol/L (95%

64 LD point and 1.05 per 1-unit decrease in the serum sodium concentration for values between 125 and 14

65 e average daily area under the curve for the serum sodium concentration from baseline to day 4 and th

66 Vasopressin antagonists increase the serum sodium concentration in patients who have euvolemi

67 aucasian male populations; in addition, mean serum sodium concentration is lower among subjects with

68 ccording to the MELD score combined with the serum sodium concentration might have resulted in transp

69 Thirteen percent had hyponatremia (a serum sodium concentration of 135 mmol per liter or less

70 1 M NaCl to induce a 25 to 28 mM increase in serum sodium concentration over 200 min or an infusate t

71 ay be continued at rates of 2/1/0.5 ml/kg/h; serum sodium concentration should be measured periodical

72 An increase in serum sodium concentration significantly decreases ICP a

73 Fluctuation in serum sodium concentration was also independently associ

74 t, the combination of the MELD score and the serum sodium concentration was considerably higher than

75 entration, indicating that the effect of the serum sodium concentration was greater in patients with

76 t 12 hrs correlating with an increase in the serum sodium concentration was observed in patients with

77 Both the MELD score and the serum sodium concentration were significantly associated

78 We examined the association of serum sodium concentration with all-cause mortality in a

79 ronic kidney disease, but the association of serum sodium concentration with mortality in such patien

80 Hyponatremia (serum sodium concentration, <135 mmol per liter) is a pr

81 ion was found between the MELD score and the serum sodium concentration, indicating that the effect o

82 rdial infarction, male sex, body mass index, serum sodium concentration, non-white race, treatment wi

83 th an aquaresis that leads to an increase in serum sodium concentration.

84 ) score with and without the addition of the serum sodium concentration.

85 over 200 min or an infusate that maintained serum sodium concentration.

86 aline administration may further depress the serum sodium concentration.

87 reflected clinically as abnormalities in the serum sodium concentration.

88 ptor antagonist, was effective in increasing serum sodium concentrations at day 4 and day 30.

89 Serum sodium concentrations increased more in the tolvap

90 Serum sodium concentrations obtained immediately prior t

91 quisition of dysnatremia and fluctuations in serum sodium concentrations on hospital mortality in the

92 Serum sodium concentrations significantly predicted mort

93 us infusion of 3% saline/acetate to increase serum sodium concentrations to 145 to 155 mmol/L.

94 Fluctuations in serum sodium concentrations were independently associate

95 Despite similar serum sodium concentrations, clinical manifestations can

96 daily sodium and fluid intake, weight loss, serum sodium concentrations, gender, gestational age, pn

97 We monitored continuously mean ICP, serum sodium concentrations, mean arterial pressure, cer

98 arterial pressure, central venous pressure, serum sodium concentrations, serum osmolarity, and serum

99 o 60 mg daily, if necessary, on the basis of serum sodium concentrations.

100 nic saline is an effective agent to increase serum sodium concentrations.

101 We developed a new PELD score using serum sodium, creatinine, and updated original PELD comp

102 telet count, international normalized ratio, serum sodium, creatinine, bilirubin, albumin, and etiolo

103 rgest median absolute decrease from baseline serum sodium ([+] DDAVP, 0 mEq/L [0-5 mEq/L] vs [-] DDAV

104 Hemodynamics, inotrope score, and serum sodium did not differ between groups at any time p

105 Renal dysfunction and serum sodium disturbances are negative prognosticators i

106 Pre-OLT serum sodium does not have a statistically significant i

107 the largest absolute decrease from baseline serum sodium during the first 3 treatment days and new-o

108 ed at outpatient week 1, but body weight and serum sodium effects persisted long after discharge.

109 , HF risk was increased by 39% if middle age serum sodium exceeded 143 mmol/L corresponding to 1% bod

110 The increase in serum sodium exceeded the desired 1 mmol/L per h at init

111 c significance of persistent ascites and low serum sodium for low MELD score patients was confirmed i

112 .83 +/- 5.95 to 294.33 +/- 3.90 mOsm/kg) and serum sodium (from 114 +/- 2.07 to 136.67 +/- 3.82 mmol/

113 and ischemia times for the peak or terminal serum sodium groups.

114 predictors of early mortality included DDLT, serum sodium >140 mEq/L, MELD >35, pH <7.3, and grade 4

115 m AST/ALT >500, maximum bilirubin >2.0, peak serum sodium >170, HBV/HCV/HTLV reactive, donation after

116 o were aged >18 years old, had a predialysis serum sodium >=135 mM, and were receiving hemodialysis a

117 ho were diagnosed with severe hypernatremia (serum sodium >=155 mmol/L) at admission or during hospit

118 of 2,175 subjects, 1,495 (68.7%) had normal serum sodium (>135 mEq/L) at OLT, whereas mild hyponatre

119 Serum sodium had no impact on survival up to 90 days aft

120 pressure (HR 0.98, 95% CI 0.97 to 0.99), and serum sodium (HR 0.93, 95% CI 0.90 to 0.96).

121 In conclusion, persistent ascites and low serum sodium identify patients with cirrhosis with high

122 luding points for persistent ascites and low serum sodium, improved prediction of early pretransplant

123 The prognostic value of serum sodium in ADHF was diminished compared with chlori

124 Incorporation of serum sodium in organ allocation may not adversely affec

125 The prognostic value of serum sodium in patients hospitalized for worsening hear

126 A decrease in edema and a normalization of serum sodium in patients with hyponatremia were observed

127 An increase in serum sodium in the first 48 hours of ICU admission was

128 reduced body weight and edema and normalized serum sodium in the hyponatremic patients.

129 not differ importantly, for peak or terminal serum sodium, in posttransplant alanine aminotransferase

130 30 mmol/L; IQR, 128-132), corresponding to a serum sodium increase of 4.1 mmol/L (95% confidence inte

131 Serum sodium increase was associated with increase in to

132 Mean serum sodium increased from 130.8 mmol/L at baseline to

133 er, laboratory variation and manipulation of serum sodium is a concern.

134 lized for worsening heart failure, admission serum sodium is an independent predictor of increased nu

135 infarction (AOR 1.59, 95% CI 1.17, 2.16), a serum sodium less than 133 on admission (AOR 1.96, 95% C

136 rs of the time to death were age (older) and serum sodium level (lower), irrespective of the serum cT

137 The primary outcome was mean serum sodium level at 48 hours.

138 Median serum sodium level at baseline was 131 mmol/L (IQR, 130-

139 yponatremic encephalopathy by increasing the serum sodium level by 4 mEq/L to 6 mEq/L within 1 to 2 h

140 An abnormal serum sodium level is the most common electrolyte disord

141 These results suggest that donor serum sodium level likely has little clinical impact on

142 HAH was defined as development of a serum sodium level of </=135 mEq/L during hospitalizatio

143 Hyponatremia is defined by a serum sodium level of less than 135 mEq/L and most commo

144 After treatment with empagliflozin, median serum sodium level rose to 134 mmol/L (IQR, 132-136), wh

145 a sliding scale was used to achieve a target serum sodium level that would maintain ICP <20 mm Hg onc

146 The association of serum sodium level with mortality was U-shaped, with the

147 ft ventricular (LV) systolic function, lower serum sodium level, and older age.

148 of falling compared with people with normal serum sodium levels (23.8% vs 16.4%, respectively; P < .

149 TIPS (OR 1.3 [1.0-1.7]; p = 0.03) and lower serum sodium levels (OR 0.9 [0.9-1.0]; p = 0.004) were i

150 terval [CI], 1.098-6.779; P = 0.031), pre-LT serum sodium levels (OR, 1.118 per mEq/L increase, 95% C

151 ent, the incidence of CPM did correlate with serum sodium levels (P < 0.01).

152 ariate analysis showed that low preoperative serum sodium levels (P = 0.012), histological cirrhosis

153 (P < 0.001, HR = 9.83, 95% CI = 4.51-21.45), serum sodium levels (P = 0.03, HR = 0.96, 95% CI = 0.92-

154 eteriorated in the hospital had decreases in serum sodium levels (P=0.007), and increases in body tem

155 The importance of serum sodium levels and the presence of ascites in the p

156 The presence of ascites and serum sodium levels are important variables associated w

157 Both lower and higher serum sodium levels are independently associated with hi

158 The direct medical costs of abnormal serum sodium levels are not well understood.

159 Serum sodium levels became significantly different from

160 The primary end point was the difference in serum sodium levels between treatments.

161 ich oxcarbazepine can lead to a reduction of serum sodium levels could have therapeutic implications

162 ange upper and lower bounds, and incorporate serum sodium levels improved wait-list mortality predict

163 graft rejection, despite similar mean BP and serum sodium levels in HSD and normal salt diet (NSD) gr

164 ance of serum chloride levels in relation to serum sodium levels in patients with ADHF.

165 Patients with serum sodium levels of <130, 130 to 135.9, 145.1 to 150,

166 rtonic saline (30%) via infusion to maintain serum sodium levels of 145-155 mmol/L.

167 In patients with hyponatremia, serum sodium levels significantly increased.

168 emia, may benefit from maintenance of stable serum sodium levels to minimize post-LT CNS complication

169 Both peak and terminal serum sodium levels were categorized as (1) severe for a

170 Fever, vomiting, and abnormal serum sodium levels were more common in children.

171 , 1 month to 18 years), with normal baseline serum sodium levels who were anticipated to require intr

172 um <135 mmol/L), 162,829 (97.3%) with normal serum sodium levels, and 3196 (1.9%) with hypernatremia

173 wever, ETx stimulated early diuresis,reduced serum sodium levels, and had more pronounced vasodilator

174 lood pressure, better renal function, higher serum sodium levels, and male sex also independently pre

175 concentrated on the clinical significance of serum sodium levels.

176 ignificantly based on peak or terminal donor serum sodium levels.

177 f MELD and 2 modifications (MELDNa [includes serum sodium levels] and MELD-XI [does not include inter

178 Serum sodium (lower) was an independent predictor of all

179 C-reactive protein >=20 mg/l and serum sodium <125 mM/l were associated with more severe

180 In conclusion, serum sodium <126 mEq/L at listing or while listed for t

181 The risk of death with serum sodium <126 mEq/L at listing or while listed was i

182 CGA) in 150 patients with age >=70 years and serum sodium <130 mEq/L.

183 ogen >/=30 mg/dL (OR, 1.5; 95% CI, 1.1-2.2), serum sodium <130 mmol/L (OR, 1.8; 95% CI, 1.02-3.1), he

184 .1%), respectively, but no participant had a serum sodium <130/>150 mmol/L or potassium <3.0/>6.0 mmo

185 000/mm3, C-reactive protein >=70.0 mg/L, and serum sodium <135 mEq/L.

186 were 1274 patients (0.8%) with hyponatremia (serum sodium <135 mmol/L), 162,829 (97.3%) with normal s

187 e symptoms, diabetes mellitus, lung disease, serum sodium <140 mEq/L, atrial fibrillation or flutter,

188 Serum sodium <= 133 mmol/L, albumin <= 3.2 g/dl, ALT >=

189 MELD score, persistent ascites, and low serum sodium (<135 meq/L) were independent predictors of

190 s not on dialysis, ln albumin, ln bilirubin, serum sodium<134 mEq/L, status-1, previous LT, transjugu

191 , low urine specific gravity, and increasing serum sodium, measured in close proximity.

192 n 24 hours of ICU admission and at least one serum sodium measurement 24-48 hours after ICU admission

193 ts 24-48 hours after ICU admission and first serum sodium measurement at ICU admission ( 48 hr-[Na])

194 Adult patients were included if at least one serum sodium measurement within 24 hours of ICU admissio

195 cerebral demyelination are correction of the serum sodium more than 25 mEq/L in the first 48 hours of

196 The serum sodium/myo-inositol cotransporter gene is located

197 was previously upgraded through inclusion of serum sodium (Na) concentrations (MELD-Na).

198 Serum sodium (Na) concentrations have been suggested as

199 ated with the relative decrease in SBP were: serum sodium (Na) decrease, body mass index, serum album

200 Inclusion of serum sodium (Na) into the MELD score was found to impro

201 Decreasing preoperative serum sodium (odds ratio, 1.41; 95% confidence interval,

202 90-year-old attendees of Visit 5 (N = 4961), serum sodium of 142.5-143 mmol/L was associated with 62%

203 ox proportional hazards analysis showed that serum sodium on admission, when modeled linearly, predic

204 6 (5.1%), respectively; out of normal range serum sodium or potassium was observed in 4 (6.3%), 12 (

205 ition and fluid rate to prevent disorders in serum sodium or volume status from occurring.

206 0.001) with no incremental contribution from serum sodium (P=0.49).

207 U increase (HR: 1.22, 95% CI: 0.96 to 1.55), serum sodium, per unit increase (HR: 0.93, 95% CI: 0.87

208 serial measurements of serum osmolality and serum sodium, plasma arginine vasopressin (AVP), and pla

209 Serum sodium, potassium, and chloride concentrations; se

210 inine and postoperative blood urea nitrogen, serum sodium, potassium, bicarbonate, and albumin from t

211 correlated with hemoglobin, hematocrit, and serum sodium, potassium, creatinine, and osmolality.

212 Stage Liver Disease score, Child-Pugh score, serum sodium, previous variceal bleeding, cirrhosis etio

213 el of end-stage liver disease, incorporating serum sodium score was 18 (14-22); and 37 had hepatocell

214 el of end-stage liver disease, incorporating serum sodium score, hepatocellular carcinoma diagnosis,

215 Accordingly, serum sodium should be maintained at least within high n

216 However, the total change in serum sodium should not exceed 5 mEq/L in the initial 1-

217 Risk in Communities Study demonstrated that serum sodium significantly contributes to prediction of

218 ient weight measurement while receiving IVF, serum sodium testing, and adverse events.

219 d difference, -1.2%; 95% CI, -2.9% to 0.4%), serum sodium testing, or adverse events.

220 cts of VRA are rare, and the rate of rise in serum sodium that they produce seems unlikely to lead to

221 infusion of 3% hypertonic saline to increase serum sodium to levels necessary to reduce ICP < or =20

222 Addition of serum sodium to MELD increases the ability to predict 3-

223 transplantation and whether the addition of serum sodium to MELD was superior to MELD alone.

224 Serum sodium transiently increases postprandially but ca

225 , peripheral edema, systolic blood pressure, serum sodium, urea, creatinine, and albumin) performed s

226 L during hospitalization in the setting of a serum sodium value >135 mEq/L on admission.

227 ided into 2 groups according to their median serum sodium value (<140 or >=140 mEq/L).

228 CAH was defined as a serum sodium value of </=135 mEq/L at the time of hospit

229 There was a steady increase in serum sodium versus time zero that reached statistical s

230 The pooled mean baseline serum sodium was 125.0 mmol/L (95% CI, 122.6-127.5 mmol/

231 107 mm Hg in those not receiving inotropes, serum sodium was 134 versus 137 mEq/L, and left ventricu

232 The mean highest serum sodium was 170.7 mEq/L (range, 157-187 mEq/L).

233 Lower serum sodium was associated with higher in-hospital and

234 An increase in serum sodium was independently associated with a higher

235 Serum sodium was measured, serum osmolality was calculat

236 Serum sodium was reduced (133.0 +/- 0.9 mmol/l furosemid

237 Serum sodium was significantly higher in the hypertonic

238 At higher doses, serum sodium was significantly increased; AVP antagonism

239 Because ascites is associated with low serum sodium, we evaluated serum sodium as an independen

240 d upon listing MELD with and without listing serum sodium were 0.883 and 0.897, respectively, and at

241 odel, it was found that serum osmolality and serum sodium were lowered much less in UT-A1 knockout mi

242 SDNN, creatinine, and serum sodium were related to progressive heart failure d

243 left ventricular end-systolic diameter, and serum sodium were significant predictors of all-cause mo

244 ests, pulmonary capillary wedge pressure and serum sodium were strong predictors of survival (p < 0.0

245 stration of tolvaptan maintains an increased serum sodium with an acceptable margin of safety.

246 t water balance dysregulation were selected: serum sodium within normal range (135-146 mmol/L), not d