ライフサイエンスコーパス: serve @2 role

1 move on tracks within cells have evolved to serve this role.

2 Therefore, spike 2158-2159 might serve a similar role.

3 ator of oxidative stress genes whereas SpxA2 served a backup role.

4 per, we demonstrate that thermodynamics also serves a crucial role.

5 rough a variety of mechanisms, with proteins serving pivotal roles.

6 ts that are rarely co-opted by the genome to serve a beneficial role.

7 isk for CRPA colonization acquisition and/or serve a protective role.

8 nality during viral LRI, with PD-1 and LAG-3 serving prominent roles.

9 y facilitates chromatin opening, whilst Oct4 serves an accessory role.

10 een the two steps of splicing, with eta-eta' serving an ancillary role.

11 se sensitive, consistent with hepoxilin A(3) serving a chemotactic role.

12 that of a load-shifting process transiently serving a compensatory role.

13 As (ssRNAs) are ubiquitous RNA elements that serve diverse functional roles.

14 d doubly, palmitoylated states that may also serve distinct functional roles.

15 of the MAPK terminal effectors, potentially serving a cardioprotective role.

16 s with different population coupling tend to serve different functional roles.

17 e pathway for these reactions in which water serves multiple beneficial roles.

18 These bacterial chips serve dual roles: (1) They can be applied as MALDI-MS ta

19 factors, suggesting that the acidic cluster serves a protective role against unwanted proteolysis by

20 tamination--and for the past 60 years it has served a role analogous to that of a model organism.

21 t, the nervous system generates neurons that serve highly specialized roles and, accordingly, possess

22 JAM-A serves many roles and contributes to barrier function an

23 in different locations throughout the body, serve distinct roles, and are activated by a variety of

24 obial competition; however, which components serve purely structural roles, and which serve as toxic

25 n source of Wnt ligands in the thymus, which serves a nonredundant role, and lack of TEC-provided Wnt

26 emerging consensus that this cis interaction serves a protective role, and that the disruption of thi

27 The LFA may serve a role as a rapid test that may replace convention

28 crete the putative glucanase Exg8, which may serve a similar role as Eng1 in removing exposed beta-gl

29 Natural products (NPs) serve important roles as drug candidates and as tools fo

30 ds constitute a diverse group of lipids that serve important roles as structural entities of biologic

31 ince its discovery in 1989, the receptor has served a pivotal role as the prototype cytokine receptor

32 ne sensor for cyclic dinucleotides that also serves a dual role as an adaptor molecule for a number o

33 ATF6 serves an important role as a previously unappreciated l

34 em includes a nanostructured Au surface that serves dual roles as the electrochemical working electro

35 s are consistent with the new copper complex serving its intended role as a photoredox catalyst, work

36 Golgi cells (GoCs) serve these roles at the input layer of the cerebellar c

37 In zebrafish, Rohon-Beard (RB) neurons serve this role at embryonic and larval stages of develo

38 ROS serve a dual role; at high concentrations they act as mi

39 sible after acute resuscitative efforts, may serve therapeutic roles beyond providing calories and pr

40 ual function of the phenylsilyl group, which serves a crucial role both in the synthesis of a novel a

41 ing conflict is integral to decision-making, serving a central role both in the subjective experience

42 nly genetically engineered system capable of serving the dual role both as an effective PET imaging r

43 opulation of resident brain macrophages that serves key homeostatic roles but also has the potential

44 These factors do not serve classical structural roles, but rather regulate ma

45 of highly homologous cohesin domains, which serve a dual role by coordinating a multiplicity of enzy

46 inalis (BST) are highly similar regions that serve complimentary roles by integrating fear- and anxie

47 hia coli DNA polymerases (Pol) II, IV, and V serve dual roles by facilitating efficient translesion D

48 he transient receptor potential (TRP) family serve important physiological roles by opening in respon

49 port a mechanism in which the ClBcat reagent serves a bifunctional role by sequentially activating th

50 entiated neuroblastoma cells, and that CRLF1 serves its protective role by a cell autonomous mechanis

51 A strategic nitrogen atom chiral auxiliary serves three critical roles, by (1) enabling in situ ass

52 Although it serves an important role, careful consideration of VUS r

53 utation in an inedible ancestral strain that served a protective role converted it to a "domesticated

54 e that dorsomedial and dorsolateral striatum serve fundamentally different roles during place learnin

55 tes within ticks from mammalian antibody and serves an additional role during tick colonization.

56 g interaction between Arg254 and Asp256 that serves an important role during DNA synthesis reactions.

57 By doing so, Daple serves two opposing roles; earlier during oncogenesis it

58 mammalian cells; such mismethionylation may serve a beneficial role for cells to protect their own p

59 Our results suggest polyploidy may serve a protective role for neurons and glia in adult Dr

60 associated with stress resilience that might serve a protective role for the neurovasculature.

61 ssential protein for virus viability but can serve a stimulatory role for replication in some culture

62 g levels of Na(+) and K(+) , ions assumed to serve important roles for the human pathogen, Plasmodium

63 its polymer-like behavior, kinetoplasts can serve that role for 2D and catenated polymer systems.

64 ent eukaryotic assemblies that have probably served cellular housekeeping roles for at least one bill

65 conserved motif corresponding to mutant A49 serves an important role for establishing a physical con

66 coevolution despite the fact that TART-A is serving a critical role for its host genome.

67 thought to be ubiquitously expressed and to serve 'housekeeping' roles in controlling protein homeos

68 These findings may serve a benchmark role in evaluating the efficacy of nov

69 naling pathway and its effector beta-cat/TCF serve a beneficial role in suppressing hepatic gluconeog

70 rated oxidation products of cholesterol that serve a central role in mediating cholesterol homeostasi

71 We propose that LINC complexes serve a conserved role in DNA repair through both the in

72 activity of inflammatory cytokines, PHD3 may serve a critical role in degenerative disc disease.

73 Promoters serve a critical role in establishing baseline transcrip

74 citability of I-wave generating pathways may serve a critical role in modulating motor cortical excit

75 n the upper and lower respiratory tracts may serve a critical role in preventing pneumonia due to Str

76 Thus, VTA(Vgat+) neurons serve a critical role in the control of rotational kinem

77 aride locus bpsABCD has been demonstrated to serve a critical role in the development of mature biofi

78 excitatory and inhibitory synapses, and they serve a critical role in the spatiotemporal regulation o

79 discuss whether exome sequencing can come to serve a dual role in diagnosis and discovery.

80 ies, suggesting that ER-associated ribosomes serve a global role in mRNA translation.

81 Thus, miR-515-5p may serve a key role in human trophoblast differentiation; i

82 Cytotoxic lymphocytes serve a key role in immune homeostasis by eliminating vi

83 n intermediate stage in visual hierarchy and serve a key role in the increasing functional specializa

84 mature biofilms and the bpsABCD locus would serve a key role in this process.

85 These proteins serve a limited role in hemostasis, suggesting that anti

86 This study shows that LV serve a novel role in the tumor microenvironment apart f

87 new evidence in rat pups that 5-HT neurones serve a physiological role in autoresuscitation.

88 This pathway may serve a physiological role in the maintenance of mitocho

89 the associated auditory signals, they likely serve a predictive role in facilitating auditory process

90 rocess, and although T lymphocytes appear to serve a prominent role in the interorgan effects of AKI,

91 that the biological functions it represents serve a protective role in AD.

92 a are not required for axon degeneration and serve a protective role in C. elegans axons.

93 ggest that the histone chaperone OsNAPL6 may serve a regulatory role in abiotic stress physiology pos

94 dian nature of adrenal Icer expression could serve a role in a time-dependent gating mechanism.

95 ulators, suggesting that isomerization could serve a role in assembling regulatory complexes in vivo.

96 K. brevis and hypothesized that brevetoxins serve a role in osmoregulation.

97 The advanced imaging methods also serve a role in selecting appropriate patients for radio

98 natal mitochondrial biogenesis and function, serve a role in the broader cardiac maturation program.

99 This input may serve a role in the maturation of the ascending (afferen

100 As (miRNAs) and histone deacetylases (HDACs) serve a significant role in the pathogenesis of a variet

101 tein from the flagellum, suggesting it might serve a similar role in Tol-Pal.

102 Noncriminal DNA databases may serve a societal role in identifying victims of crime an

103 tal ions commonly present in environment and serve a special role in Earth's history, such as Fe(3+)

104 We propose that early cortical cells serve a synchronizing role in the initiation and propaga

105 We conclude that the VOF is likely to serve a unique role in the communication of signals betw

106 Opioids serve a vital role in the current analgesic array of tre

107 ropose that decapping and lncRNA degradation serve a vital role in transcriptional regulation specifi

108 Empirical models can therefore serve an important role in advancing the understanding o

109 These findings suggest that FRZB may serve an important role in determining hip shape and may

110 tical source of type 2 cytokines in vivo and serve an important role in orchestrating the type 2 resp

111 nts a rough mineralized interface that might serve an important role in stress transfer between tendo

112 ly unrecognized structural features of NEAT1 serve an important role in these interactions.

113 MD/PhD programs serve an important role in training physician-scientists

114 Surgical video data can serve an important role in understanding the relationshi

115 These hormones may serve an integral role in protecting nonadipose tissues

116 distinct metabolic pathways but nevertheless serve complementary roles in mediating plant interaction

117 that muscarinic and nicotinic receptors may serve complementary roles in regulating coherence and sp

118 GCN2 and ATF4 serve complementary roles in the hepatic response to asp

119 idues conserved among all alphaherpesviruses serve critical roles in cytoplasmic virion envelopment a

120 or emerge among a variety of animals and may serve critical roles in fitness [1, 2].

121 GS14) that have been clearly demonstrated to serve critical roles in modulating synaptic signaling an

122 Antimicrobial peptides (AMPs) serve critical roles in mucosal defense, but their expre

123 l for membrane biogenesis and regulation and serve critical roles in protein targeting and cellular s

124 e gyrus of hippocampus, a region believed to serve critical roles in seizure generation and learning

125 l elements of mechanosignal transduction and serve critical roles in tissue repair.

126 Accordingly, the two pathways are likely to serve different functional roles in the transmission of

127 uron activity and identify subtypes that may serve different roles in micturition.

128 patterns argue that these two neuron classes serve different roles in regulating motor output.

129 We demonstrate that these domains serve different roles in regulating the kinetics of LPL

130 concentrations indicates that specific MMPs serve different roles in the pathophysiology following T

131 our GABAergic subtypes that almost certainly serve different roles in the processing of auditory stim

132 eins regulate various cellular functions and serve distinct roles in normal development throughout li

133 rtially non-overlapping, suggesting they may serve divergent roles in neuronal signaling.

134 ly to metabolize progesterone and thereby to serve diverse roles in the physiology of pregnancy in ma

135 ou4f1) as well as transcription factors that serve dual roles in hair cell and neuronal development (

136 n immunodeficiency virus type 1 (HIV-1) RNAs serve dual roles in the cytoplasm as mRNAs encoding the

137 Plastid isoprenoid-derived carotenoids serve essential roles in chloroplast development and pho

138 Carbohydrates and natural products serve essential roles in nature, and also provide core s

139 In photosynthetic organisms, carotenoids serve essential roles in photosynthesis and photoprotect

140 Lipoproteins serve essential roles in the bacterial cell envelope.

141 nts to the ventral tegmental area (VTA) that serve evaluative roles in syllable-specific learning and

142 ate cis-regulatory elements (cCREs) that may serve functional roles in regulating gene expression(1).

143 ar that exosomes (endosome derived vesicles) serve important roles in cellular communication both loc

144 , RO, and R2N) in mammalian plasma and cells serve important roles in nitric oxide (NO) dependent as

145 nnels are ATP-activated cation channels that serve important roles in sensory signaling and inflammat

146 lian liver and identifies key genes that may serve important roles in sinusoidal integrity and as mar

147 egative feedback loop regulated by TGF-beta, serve important roles in the developmental regulation of

148 ine-aspartate repeat protein D (SdrD), which serve key roles in colonization and infection.

149 ostsynaptic membrane microdomains, which may serve key roles in the function of the neuronal synapse.

150 Cellular microRNAs serve key roles in the post-transcriptional regulation o

151 Secreted proteins serve pivotal roles in the development of multicellular

152 r data demonstrate that nesprin 1 and desmin serve redundant roles in nuclear anchorage and that the

153 idence supports the notion that gangliosides serve regulatory roles in neurogenesis; little is known,

154 endent phosphorylation, which is believed to serve regulatory roles in the function of CRY2.

155 urrently in many distinct frequencies, which serve separate computational roles in cognitive function

156 F-class state, substituting for miRNAs that serve such roles in iPSCs.

157 Our data suggest that dopamine and GABA serve temporally distinct roles in these dual transmitte

158 s of in vivo/ex vivo versus in vitro samples serve unique roles in Plasmodium research.

159 roup" on the S-aryl moiety of the thio ether served a critical role in facilitating the oxidative add

160 operant in the kidney during endotoxemia and served a cytoprotective role in mitigating acute kidney

161 es of exposure to TLR agonists and that this served an essential role in supporting the de novo synth

162 These results indicate that MMP10 serves a beneficial role in response to acute infection

163 ication within and between brain regions and serves a central role in establishing complex and adapti

164 The Wnt signaling pathway serves a central role in specifying posterior cell fates

165 Ceramide, which serves a central role in sphingolipid metabolism, is gen

166 the leaderless cytokine IL-1beta and thereby serves a central role in the inflammatory response and i

167 Thus, IFN-lambda serves a critical role in bridging innate and adaptive i

168 It also serves a critical role in engaging the public with resea

169 naptic function in glutamatergic neurons and serves a critical role in learning and memory.

170 Formation of heterochromatin serves a critical role in organizing the genome and regu

171 is highly induced upon B cell activation and serves a critical role in regulating activation-induced

172 The human cathelicidin LL-37 serves a critical role in the innate immune system defen

173 The complement system serves a critical role in the modulation of immune respo

174 Thus, MMP-1 serves a critical role in the repair of damaged human sk

175 Solvent polarity serves a crucial role in changing the regioselectivity,

176 The agr-system serves a crucial role in pathogenesis by triggering subs

177 Autophagy serves a dichotomous role in cancer and recent advances

178 Each member of the PLA2 family of enzymes serves a distinct role in generating active lipid metabo

179 findings demonstrate that each Tet1 isoform serves a distinct role in the CNS.

180 findings demonstrate that each Tet1 isoform serves a distinct role in the mammalian brain.SIGNIFICAN

181 pEtN) transferase Cj0256, renamed EptC, that serves a dual role in modifying the flagellar rod protei

182 s is a novel function and indicates that VSG serves a dual role in trypanosome biology-that of facili

183 utoimmune diseases, it is unclear whether it serves a functional role in autoimmune responses.

184 toxicity due to nitrite accumulation, HcpR1 serves a global role in regulating the response to nitra

185 ot fully understood, although the centrosome serves a key role in determining when and how much repli

186 nsensus is that the autonomic nervous system serves a key role in emotional processes, by providing p

187 resses Pink1-dependent mitophagy and thereby serves a key role in hematopoietic homeostasis.

188 RAD51, RAD51AP1 (RAD51-associated protein 1) serves a key role in homologous recombination-mediated c

189 at entrainment of low-frequency oscillations serves a mechanistic role in enhancing perceptual sensit

190 The results suggest that PpeGID1c serves a primary role in vegetative growth and elongatio

191 nosine is produced in response to injury and serves a protective role in early stages of injury and i

192 n the axial and axial oblique planes, and it serves a restrictive role in internal rotation; the pubo

193 To more precisely determine whether LuxS serves a role in mammalian infection, mice were simultan

194 Thus, CD16 serves a role in NK cell-mediated spontaneous cytotoxici

195 expressed in most human adenocarcinomas and serves a role in promoting growth and the transformed ph

196 induced repression of flavonoid accumulation serves a role in removing the inherent inhibitory action

197 Previous studies suggest that TRPML2 serves a role in the immune system; however, the evidenc

198 e with other bunyavirus/vector interactions, serves a role in viral attachment and possibly in entry

199 ult splicing transitions in muscle and MBNL2 serves a similar role in the brain, the function of MBNL

200 ty and ROS accumulation, suggesting that NNT serves a specific role in mitigating the oxidation of th

201 our results suggest that ATP binding to JH2 serves a structural role in JAKs, which is required for

202 d to function as a noncatalytic subunit that serves a structural role in the complexation of the oxyg

203 s a prominent example of such regulation and serves a ubiquitous role in segregating the synthesis of

204 etabolomic analyses indicate that Kras(G12D) serves a vital role in controlling tumor metabolism thro

205 ine kinase that functions in development and serves a vital role in many human cancers.

206 Additionally, the RMTg serves a vital role in response to addiction.

207 Whether clathrin serves additional roles in receptor recycling, degradati

208 We conclude that FTY720 serves an active role in preventing photoreceptor cell d

209 To investigate whether Hp serves an additional role in nutritional immunity throug

210 ch demonstrates that the protein matrix also serves an entatic role in keeping the Met bound to the a

211 These data suggest that PTK7 serves an essential role in Flt-1-mediated angiogenesis.

212 med translation during oocyte maturation and serves an essential role in mouse EGA.

213 Although quiescence serves an essential role in preserving stem cell functio

214 that the Wiskott-Aldrich gene product (WASP) serves an essential role in T regulatory cells to contai

215 Whether IL-9 serves an essential role in the initiation of host-prote

216 ised of LIN9, LIN37, LIN52, LIN54, and RBBP4-serves an essential role in three distinct transcription

217 s showed that the enoyl CoA-hydratase MAOC-1 serves an important role in ascaroside biosynthesis and

218 argest subunit of RNA polymerase II (Pol II) serves an important role in coordinating stage-specific

219 s overexpressing oncogenes, suggesting MRE11 serves an important role in countering oncogene-induced

220 uggest that the TH9 subset of helper T cells serves an important role in driving ulcerative colitis b

221 Thus, quantification of D-dimer levels serves an important role in guiding therapy.

222 These results suggest that RAD51AP1 also serves an important role in meiotic homologous recombina

223 vely, these data demonstrate that cytoglobin serves an important role in muscle repair and regenerati

224 This localization to both SPBs serves an important role in promoting efficient exit fro

225 This demonstrates that DC-SCRIPT serves an important role in regulating GR function in DC

226 stabilizes the P1 and P3 helices, magnesium serves an important role in stabilizing a pseudoknot int

227 his consistency in backbone structure likely serves an important role in the display of an enormous d

228 ABSTRACT: The median preoptic nucleus (MnPO) serves an important role in the integration of water/ele

229 Furthermore, YBX1 serves an important role in the secretion of miRNAs in e

230 migration used only by Treg in tissues that serves an important role in their suppressive function a

231 the SWI/SNF chromatin-remodeling complexes, serves an indispensable role in cold-induced thermogenes

232 These results suggest that EF-Ts serves an unanticipated role in the cell of actively reg

233 Here we show that Akt1 serves an unexpected role in the regulation of energy me

234 G protein signaling (RGS) family of proteins serves critical roles in G protein-coupled receptor (GPC

235 previously that the UL20/gK protein complex serves crucial roles in cytoplasmic virion envelopment a

236 and vestibular hair cells suggests that GFI1 serves different roles in these systems.

237 stribution of PIST suggests that the protein serves distinctive roles in specific neuronal population

238 genic member of the FAM3 cytokine family and serves essential roles in both epithelial-mesenchymal tr

239 he mitochondrion is a complex organelle that serves essential roles in energy transduction, ATP produ

240 Myelin serves essential roles in the functioning of the nervous

241 ule-binding motor protein superfamily, which serves important roles in cell division and intraorganel

242 Ventral pallidum (VP) serves important roles in reward and motivation and is a

243 role in CCM, the E1 component of Mtb's KDHC serves key roles in situational defense that contribute

244 Homologous recombination serves multiple roles in DNA repair that are essential f

245 Corelease thus serves multiple roles in synaptic transmission.

246 us chitin in vertebrates and suggest that it serves multiple roles in vertebrate biology.

247 s simplex virus 1 (HSV-1) genome, (iv) pUL36 serves no direct role in cleavage/packaging, (v) cleavag

248 w study suggests instead that pha-1 actually serves no role in development and instead is a component

249 ents indicate that the palladacycle catalyst serves two roles in the aminocarbonylation reaction: red

250 ings provide strong evidence for aldosterone serving a causal role in renal cell cancer regulation vi

251 ous cells, and regulates tissue repair, thus serving a critical role in homeostasis, health span, and

252 in pancreatic ductal adenocarcinoma (PDAC), serving a critical role in tumor initiation.

253 r support the concept of interdomain linkers serving a dual role in substrate binding by appropriatel

254 ng recent work that recasts these regions as serving a key role in on-task control processes.

255 our data suggest the microbiome is primarily serving a nutritional role in development with only mino

256 nnate immune system identified in animals as serving an essential role in antiviral immunity.

257 regions and relay it to other brain regions, serving an essential role in sensory perception and moto

258 completed research and are now recognized as serving an important role in determining what future res

259 d maintenance of the peptidoglycan cell wall serving essential roles in survival in the host environm

260 crophages are now increasingly recognized as serving many roles in tissue development, homeostasis an

261 Primary cilia in different organs serve diverse roles including osmosensing, but its contr

262 How the same cytokine can serve two opposing roles is a subject of current investi

263 plasma membrane receptor termed STRA6, which serves a dual role: it mediates transport of retinol fro

264 zed by STRA6, a plasma membrane protein that serves a dual role: it mediates uptake of retinol from e

265 zed by STRA6, a plasma membrane protein that serves a dual role: it transports retinol from extracell

266 ributions to research and teaching, and they serve as positive role models to others aspiring to such

267 TMEG can serve dual role of extracting the waste heat and convert

268 amps are loaded onto DNA by clamp loaders to serve the critical role of coordinating various enzymes

269 Here, peroxides serve the dual role of oxidants as well as alkylating or

270 The g-C(3)N(4) NS served dual role of detection as well as photocatalytic

271 During the halogenation, CuX2 served the dual role of a halogen source as well as a co

272 est that SYP121 binding to the K(+) channels serves the role of a primary trigger to initiate assembl

273 A major feature is a helix serving the dual role of the N-terminal helix of the KD

274 of plant biomass and its nanomaterials, may serve a leading role on developing new hierarchical mate

275 nctional receptor-receptor coupling seems to serve a modulatory role on both channels, this might not

276 other components of microfibrils; these may serve structural roles, providing stability to ducts and

277 esis that cerebellar Purkinje neuron atrophy serves an adaptive role rather than being simply a nonsp

278 stem/progenitor cells, yet how this pathway serves these dichotomous roles remains enigmatic.

279 To serve numerous functional roles, RNA must fold into spec

280 EHD4 serves a role similar to that of EHD1 in TRE vesiculatio

281 However, these receptors serve complementary roles, such that double-knockout MIG

282 re negative clock element FREQUENCY (BcFRQ1) serves additional roles, suggesting extracircadian funct

283 However, it is now clear that MRP1 serves a broader role than simply mediating the ATP-depe

284 at downstream cortico-basal ganglia circuits serve a learning role that is only premotor.

285 ce of sufficient levels of alpha2(V) chains, serve functional roles that partially compensate for los

286 These modifications may serve a feedback role to maintain leptin concentrations

287 Among these, memory T cells serve a sentinel role to protect against pathogens, and

288 The two parameters may serve a similar role to Vmax, KM, and kcat in classical

289 We conclude that HXA3 and LTB4 serve independent roles to collectively coordinate an ef

290 g evidence that N-fixing trees do not always serve the facilitative role to neighboring trees during

291 PNs) are a largely transient population that serves a critical role to establish functional cortical

292 ted induction of DNA damage, TRF1 deficiency serves a protective role to limit induction of DNA damag

293 Thus, recruitment of NO is serving a compensatory role to boost synaptic transmissi

294 rRNA control ribosome assembly and could be serving a regulatory role to couple ribosome assembly to

295 ing Center (DRSC) at Harvard Medical School, serves a dual role, tracking both production of reagents

296 uggesting that the eIF4A binding domains may serve a regulatory role, with the C-terminal binding sit

297 es, which together suggests that SPARC might serve a specific role within muscle cells.

298 es, in addition to a crystallographic water, serve critical roles within the enzymatic mechanism.

299 T High-frequency spike-bursts are thought to serve fundamental computational roles within neural circ

300 >50 kDa) with tetratopic pyridinyl subunits serving different geometrical roles within the structure