ライフサイエンスコーパス: several

1 While structural information exists for several A3 proteins, the precise details regarding deami

2 K8 positively regulates the transcription of several ABA-responsive genes, probably through promoting

3 r further experimental validation as well as several accompanying data visualisations.

4 Several acute myeloid leukemia genetic sub-types converg

5 Several adaptive scenarios may have favored this functio

6 Several additional examples of cascade cyclizations of a

7 and environmental health research may offer several advantages and new options to help control the d

8 rom human pluripotent stem cells, which have several advantages over fetal cell-derived therapies.

9 It can offer several advantages over intravenous administration.

10 nary distributions of movement syllables has several advantages over traditional neurologist administ

11 We also included several agro-morphological traits related to leaves, ste

12 tly debated in the years that followed, with several alternative interpretations put forth to explain

13 at are highly reactive and footprint broadly several amino acid residue side chains on the time scale

14 Several analogues showed inhibition, which is a positive

15 genome-wide cross-trait analysis features in several analytic aspects: genetic correlation, cross-tra

16 Copy number variants (CNVs) are pervasive in several animal and plant genomes and contribute to shapi

17 in-depth analysis uncovered the presence of several antimicrobial resistance genes.

18 Several approaches have been proposed for the integratio

19 Among them, several are involved in plant-pathogen response, which c

20 Several asparaginase-associated toxicities were studied.

21 e development of atopic dermatitis (AD), but several aspects of this association remain unclear.

22 stematically researched these anomalies from several aspects, especially the influencing forces.

23 es of spreading out the positive charge over several atoms.

24 While several ATP analogues gave responses of similar magnitud

25 investigate the development and stability of several attributes of continuous no-till as compared to

26 Several auto-Ags are fundamental to disease development,

27 Among the several available guidelines for the management of knee

28 ntraepithelial neoplasia (PanIN), along with several biochemical approaches and immunofluorescence mi

29 molecular weight protein size standards and several biotherapeutic proteins were studied in sodium d

30 trum disorders and neural circuit changes in several brain areas, but the cellular mechanisms that un

31 ment of small molecule compounds that target several cancer drivers has shown great therapeutic poten

32 ons are frame-shift mutations that result in several cancer-specific neoantigens that activate T-cell

33 Green and colleagues recently identified several candidate RAN translation inhibitors from a high

34 Several case studies are presented, including data-drive

35 ng alteration of the E2 antigenic profile in several cases, and one design led to improvement of cros

36 activation energy of reactions by performing several catalytic functions.

37 diction of regulatory effects per variant on several cell type-specific chromatin features.

38 Prominent actin cables, spanning several cells, are abundant both in cultured aggregates

39 ify immune-related adverse events, there are several challenges in interpreting the results of this i

40 Furthermore, several chaperone proteins associated with the responses

41 n linked to the prevention and management of several chronic and degenerative diseases including canc

42 tion of AFFF-associated PFSAs and identifies several classes of potentially bioaccumulative novel PFA

43 s been challenged with the identification of several clinical subtypes, pathogenic genes and putative

44 In 2016, several clinicians involved in the diagnosis, management

45 ign, synthesis, and biological evaluation of several close-in analogs of bryostatin 1.

46 est this, we have measured the signatures of several combination samples containing two or four diffe

47 ) and deuterium (D) isotopes of methane, and several combustion tracers.

48 y in the peroxisome to convert acetyl-CoA to several commercially important monoterpenes and achieve

49 ic syndrome is a significant risk factor for several common cancers (e.g., liver, colorectal, breast,

50 rade systemic inflammation and contribute to several common chronic diseases.

51 Genetic faults in several components of the nuclear factor-kappaB pathway

52 The screen identified several compounds that interfere with transcription, DNA

53 Several compounds were transformed during ozone pretreat

54 stable isotope-labelled protein composed of several concatenated signature peptides as internal stan

55 (II) and with HNO(3) to recover Hg(II) after several consecutive adsorption/desorption cycles.

56 We identified several consequences of EAE that may contribute to these

57 features extracted from PPG, whereas for DL several convolutional neural networks (CNNs) have been a

58 esviruses is a powerful nanomachine built by several copies of a large (TerL) and a small (TerS) term

59 ream cultural acceptance and legalization in several countries worldwide.

60 ome in mice with regard to its dependency on several critical experimental factors, including the tim

61 umed to attend (and learn about) only one of several cues on each trial.

62 Impact on carbapenem use was assessed at several cut-off points.

63 software package that seamlessly integrates several cutting-edge, computationally efficient techniqu

64 l epithelial cells secreted large amounts of several cytokines and chemokines, especially tumor necro

65 rization of major PTMs is well documented in several databases.

66 Several datasets are analysed and our results clearly il

67 able circulating HoxB8 neutrophil counts for several days.

68 ased significantly and remained elevated for several days.

69 the use of a select few lyases over the last several decades, limiting the types of C-C bond-forming

70 flux calculations suggest the involvement of several decarboxylating pathways in the Kok effect, incl

71 tic elements (MGEs), bacteria have developed several defense mechanisms, some of which target the inc

72 t of the overall topology was examined using several deletion variants.

73 anism of the Msr enzymes have been reported, several details still await full elucidation.

74 nal repressor that regulates neurogenesis in several developmental contexts.

75 Apigenin significantly improved several developmental milestones and spatial olfactory m

76 Several dialysis center characteristics were associated

77 proven to be an effective immunotherapy for several different cancers.

78 Several different materials varying in size and shape we

79 enotype influences primary hemostasis though several different pathways.

80 nts at individual cells can be used to study several different tissues and organs at different stages

81 Its epithelium consists of several differentiated cell types, including acinar, duc

82 rs and regulators to improve the therapy for several disease states.

83 lled by an S-locus "supergene" consisting of several distinct genes that determine different traits o

84 Although there are several distinct PIV serotypes, few studies have compare

85 ivities, APE1 must recognize and accommodate several diverse DNA substrates.

86 mote equity, diversity, and inclusion across several domains including ethnicity and gender.

87 e is characterized by significant changes in several domains, including brain structure and function,

88 a necro-inflammatory liver disease caused by several drugs commonly used in clinical practice, herbs

89 It includes several early-diverging groups of generally large-bodied

90 Furthermore, ARDKO cells exhibited several electrophysiological changes such as action pote

91 ly, we offer a critical review and highlight several emerging approaches to promote tumor retention a

92 lm formation by P. fluorescens and discusses several emerging models for the regulation and function

93 f the authors with a comprehensive search of several English-language databases and a manual review o

94 utionarily ancient protein domain present in several enzymes that hydrolyze cyclic phosphate bonds on

95 HOTAIR is a lncRNA overexpressed in several epithelial cancers and strongly correlated with

96 Several essential conditions for in vitro transcription

97 te a marked nonvascular disruption in T1D of several essential neural nodes engaged in both cognitive

98 gical data on the implementation of NPIs for several European and non-European countries between Janu

99 re, the activity of CX-6258 was validated in several Ewing sarcoma and multiple myeloma cell lines.

100 This mechanism was supported by several experimental findings obtained using biochemical

101 of a multicomponent cascade compatible with several external trapping agents.

102 SPC in orange juice are laborious, requiring several extractions with successive adjustments hinderin

103 Several factors contributed jointly to higher rates of l

104 Though several factors have been reported to influence the CLA

105 Several FAs mimic DSFs and control motility, fimbriae, h

106 Phakic RD with cataract shared several features in common with pseudophakic RD.

107 as an important supplement of the database, several flexible tools have been developed to aid retrie

108 eine-rich Bowman-Birk protease inhibitor was several fold higher in transgenic soybean plants when co

109 ical structures that have been identified in several foldamer families can serve as scaffolds for the

110 bonucleases to degrade structured RNA during several forms of environmental stress.

111 Several functional analyses are performed on this model

112 EMENT Oxytocin is a neuropeptide involved in several functions ranging from lactation to social attac

113 We found notable contractions in several gene families in J. hindsii, including disease r

114 Several genera of the Cactoideae and Pereskioideae subfa

115 ne and that gigC regulates the expression of several genes involved in the sulfur assimilation and cy

116 Variants in several genes, such as those causing connective tissue d

117 -induced GPCR activity has been reported for several GPCRs.

118 ing neurons regulated male sleep, suggesting several groups of PB-projecting neurons act downstream o

119 Several H-H bond forming pathways have been proposed for

120 ses, but the fundamental frequency and first several harmonics are missing or attenuated, and peak fr

121 As such, several hexagonal oxide perovskites have been identified

122 In recent years, several hierarchical extensions of well-known learning a

123 existing social and health disparities among several historically vulnerable populations, with stark

124 nses, visually naive ferrets were exposed to several hours of experience with unusual spatiotemporal

125 rray to examine the binding selectivities of several HS-binding proteins.

126 e spine segmentation defects have implicated several human orthologues of cyclic genes that are assoc

127 Though several hundred clinical trials have tested immune-based

128 ed to implement at such voltages higher than several hundreds of volts.

129 a combined electrochemical cell composed of several identical ion-selective electrodes immersed into

130 Our results indicate several immunosuppressive mechanisms that may be simulta

131 Although several immunotherapeutic agents have been utilized in t

132 nts provide effective prophylaxis, there are several important caveats associated with their use, inc

133 ing knowledge from these studies has enabled several important recent breakthroughs.

134 Several in vitro and in vivo mechanisms involved in PDAC

135 expression that are aberrantly regulated in several inflammatory and infectious diseases.

136 ned increased levels of putative markers for several inflammatory diseases, which were reduced by the

137 reward, and decision-making, and observed in several interacting frequency bands.

138 ceeded through a cascade mechanism involving several intermediates identified by mass spectrometric a

139 solo LTRs to tandem dRemp repeats containing several internal LTRs, suggestive of extensive recombina

140 ic innervation of associative cortex targets several interneuron types, modulating dynamics and influ

141 Selection behaviors have been studied under several intersecting umbrellas including decision-making

142 This method was successfully used in several 'inverse drug discovery' programs that use high-

143 The construct is polyhedric, comprising several key forms: grandiose versus vulnerable, agentic

144 d tumors, IGFBP2 is upregulated and promotes several key oncogenic processes, such as epithelial-to-m

145 criptional events, control the metabolism at several levels.

146 While our original method was promising, several limitations persisted, including access to more

147 ngivalis, is a key periodontal pathogen, and several lines of evidence link the presence of this bact

148 er stages) of the viral life cycle, based on several lines of evidence.

149 resence of HPG and KoRV-related sequences in several locations across northeast Australia, as well as

150 ity density function analysis indicates that several long-terminal-repeat bursts that occurred from 5

151 ) is causally linked to Kaposi's sarcoma and several lymphoproliferative diseases.

152 separate permutations of the actual data for several MAF bins.

153 However, several major classes of therapeutically relevant protei

154 (c-MET) signaling pathway is dysregulated in several malignancies, including gastric cancer, and is a

155 that target specific RNA transcripts through several mechanisms.

156 Our studies on several meningioma cell lines cultured in hypoxic condit

157 UDP-glucuronic acid is sufficient to inhibit several mesenchymal-like properties including cellular i

158 Several metabolic disease models have shown that dysregu

159 issues and their dysfunctions, which lead to several metabolic diseases including obesity or type 2 d

160 The variation in several metabolite pools such as malate, fumarate or cit

161 nd formation method is shown by synthesizing several metal complexes of 2-(benzo[d]thiazol-2-yl)pheno

162 with existing meta-analyses, and studies had several methodological shortcomings.

163 ich gave rise to F1 sporophytes that reached several millimeters before suddenly dying.

164 ent of the Phanerozoic and was followed by a several million-year delay in benthic ecosystem recovery

165 n strong geographic isolation extending back several millions of years.

166 Several missense mutations in the orphan transporter FLV

167 which is less than the typical ~40% found in several model plants under the same condition.

168 in the emergence of persistence, we consider several models of environmental volatility described by

169 oper chiral packing of the building block at several molecular scale considerably contributes to the

170 ts at 70 loci (53 of them novel) identifying several molecules and mechanisms involved in cell regula

171 Our current study examines several monophyletic species within the obscura group, a

172 ave shown impaired neurovascular function in several mouse models of AD, including the J20-hAPP mouse

173 onses were confirmed in T cells derived from several mumps cases, and MuV-specific CD8+ T cells could

174 The lead compound 48c, induced necrosis in several mutant and FLT3-resistant AML cell lines and pri

175 Several mutations resulted in only residual FcgammaRI bi

176 Several MYB recognition elements were found in the promo

177 ecular fibers in water, micrometers long and several nanometers in width, are among the most studied

178 were almost completely absent from reefs in several nations, and shark depletion was strongly relate

179 The inclusion of several nearby tissue types in this data set also led to

180 al cells latently infected with KSHV express several neuronal and NE genes.

181 d GABA correlate with impulsive behaviour in several neuropsychiatric diseases and there is post-mort

182 vironment has resulted in the description of several new phyla, many of which are globally distribute

183 Classical T4 phage engineering and several newly proposed methods are often inefficient and

184 e rattlesnake venom gland in comparison with several non-venom tissues to characterize physiological

185 and extended known associations and reported several novel causal associations providing important in

186 s into the pathogenesis of EoE have revealed several novel disease mediators that might be targeted i

187 holesterol metabolism and energy balance via several nuclear receptors and/or G-protein-coupled recep

188 dence of this third ion has been observed in several nucleic-acid-processing metalloenzymes.

189 However, the significant role of several obstetric conditions did not influence hospital

190 Several of the HZ analogues synthesized in this study ar

191 Several of these AD risk genes are specifically expresse

192 ve been linked with the expression levels of several of these architectural proteins.

193 Several of these inhibitors have advanced to clinical tr

194 Several of these monoclonal antibodies are promising can

195 aracterized in solution and the solid state, several of which are too weak - or are disfavored compar

196 classification of bosonic TCSs protected by several onsite symmetry groups and each of the 17 wallpa

197 To help address several open questions regarding the history of these mo

198 While several open-source software suites provide subdiffracti

199 f eukaryotic cells can be dramatic and spans several orders of magnitude.

200 vere chronic inflammatory diseases that span several organ systems(3-6).

201 1c+CD11c+ myeloid DCs, distribute throughout several organs in HIS mice including blood, bone marrow,

202 ue with our data inclusion criteria and make several other dubious claims regarding data processing,

203 cy with migrating focal seizures (EIMFS) and several other forms of epilepsy associated with severe i

204 f 4-OI and DMF extends to the replication of several other pathogenic viruses including Herpes Simple

205 r right hemicolectomy are currently based on several parameters (ie, tumor size, grading, proliferati

206 use of different types of aging barrels) on several parameters: color, non-enzymatic browning, antio

207 ations in this mechanism are responsible for several pathological conditions, including acute pancrea

208 irus (FMDV) leader proteinase (Lpro) affects several pathways of the host innate immune response.

209 lete the protocol within 2-3 d, allowing for several pause points during the procedure.

210 spectra of citric acid (CA) are complex, and several peaks are observed for CA and its fragments in b

211 In addition, we present several performance measures for evaluating the quality

212 We detect several phenomena predicted to arise from the existence

213 Several phenotypes that impact the capacity of cancer ce

214 rgent, and redox-economic total syntheses of several polycyclic members of the rhodonoid family of me

215 Several polygenic scores were associated with the level

216 s for 20% of myocardial infarctions (MIs) in several populations.

217 le effects of Na(+) and succinate binding at several positions suggesting distinct effects of the two

218 Here, we propose several potential explanations for the disparate nature

219 This research has identified several potential predictors for CRC in a BCSP populatio

220 in sterile tissue inflammation and identify several potential therapeutic targets.

221 e compared different scRNA-seq platforms and several preprocessing, normalization and batch-effect co

222 In conclusion, we confirmed several previously reported epitopes but also identified

223 Our analysis identifies several previously unexplored candidate blood biomarkers

224 We also report the characterization of several previously unknown halophilic viruses, many of w

225 These myeloid cells are known to secrete several proangiogenic factors in tumors, including IL-1b

226 core spliceosomal machinery is regulated by several protein factors that predominantly bind exonic s

227 Several proteins that bind to Xist RNA have recently bee

228 function as a tumour suppressor by targeting several proteins, including androgen receptor (AR), ster

229 or the treatment of Huntington's disease and several psychiatric disorders(1,2).

230 echanistic understanding of the sequelae for several psychiatric disorders.

231 Several randomised controlled trials (RCTs) have assesse

232 Several randomized trials demonstrated that chemoprophyl

233 ock in organic synthesis because it features several reaction sites with nucleophilic or electrophili

234 However, the need for several reagents and steps and the high cost of PCR hind

235 We tested several recent deep learning techniques including wide r

236 Indeed, several recent reports have pointed out spectacular diff

237 However, several recent studies suggest they may signal global mo

238 4 topoisomerase subunit gene (gp60) requires several recoding signals.

239 The conserved response revealed several regeneration-responsive enhancers (RREs), includ

240 n-European cultural mosaic (Gravettian) with several regional facies.

241 Additionally, in our data set, for several regions, male and female volumetric measures wer

242 ted mutations in the HBoV1 capsid identified several residues that are critical for transduction, cap

243 ica) represents a public health challenge in several resource poor settings.

244 for clinical islet transplantation, it poses several restrictions, especially limited tissue volume d

245 Among several reversible epigenetic changes occurring during t

246 Several risk scores combining morphological and biologic

247 fe requires flexibility in switching between several rules.

248 sitivity of the electrode remains active for several runs of the analysis.

249 st widely used imaging modalities that spans several scientific and technological fields.

250 can be addressed, and how the involvement of several sectors in addition to the health sector in mult

251 Multipartite virus genomes are composed of several segments, each packaged in a distinct viral part

252 rol on metabolic health have been studied in several short-term human clinical trials, with conflicti

253 Upon nutritional stress, several signaling pathways cooperate to change the trans

254 programmed cell death process is mediated by several signalling pathways (referred to as intrinsic an

255 One clade has replaced others at several sites, and rates of DFT1 coinfection are high.

256 Indeed, several skeletal diseases, such as bone fracture, osteon

257 ystem collapse, governments have resorted to several social distancing measures.

258 Several species of crustose coralline algae (CCA) and th

259 f techniques, we purified these serpins from several species of nonmodel treefrogs and developed a pi

260 Western blot detected several specific uEV kidney and EV markers (>=4.5 mL uri

261 equiv of ABTE allows the differentiation of several spiroglycol proton signals.

262 This correlated with improvements in several splicing defects in skeletal and cardiac muscles

263 ese analogues has excellent activity against several streptogramin-resistant strains of Staphylococcu

264 Several structurally and functionally diverse proteins h

265 Dose metrics for several structures (i.e., optic disc, macula, retina, gl

266 Several studies have found that a more extensive lymphad

267 However, several studies have now highlighted the potential for k

268 Several studies have suggested that NO plays a vast and

269 Several studies have suggested that reduced sleep durati

270 Several studies reported that the CDK inhibitor p27(Kip1

271 Several studies, focused on different types of tumors, r

272 nmental effects, and we illustrate this with several substantive examples.

273 ers included tumor-to-blood ratio as well as several SUV measures.

274 coming biological barriers and leveraging on several synergistic cancer cell killing mechanisms.

275 This tutorial will provide a brief review of several techniques used to characterize the surface and

276 Using several techniques, we show that electron paramagnetic r

277 This uncovered several that were heavily enriched in development but re

278 iodontal ligament cells (hPDL cells) express several TLRs, including TLR3, a nucleotide sensing recep

279 otifs' bind Rbfox robustly in cells and that several together can exert regulation comparable to GCAU

280 Several tools, from base-calling to genome assembly, wer

281 Several trimeric compounds were found to be capable of f

282 Herpes simplex virus 1 (HSV-1) infects several types of cells, including neurons, but has not p

283 oltage-gated potassium (Kv) channels display several types of inactivation processes, including N-, C

284 of adult-onset cancers in the United States, several types of primary cancer were significantly assoc

285 nucleoside triphosphates, and the effects of several typical additives.

286 ardiolipins and demonstrated the presence of several ubiquinones in Arabidopsis mitochondria.

287 Several underlying conditions have been associated with

288 replicative virus, comparing favorably with several vaccine formulations currently in the clinic.

289 The effect of several variables on MBLs changes was assessed via univa

290 We studied WT Cel7A and several variants in which one or two of four highly cons

291 lity of the CD8 T-cell response to recognize several variants of a single epitope is an important con

292 It offers several visualization and comparison options that are de

293 dges along climate gradients, and we discuss several ways that these factors influence the stability

294 cause it builds high-affinity bonds by using several weak binding interactions simultaneously.

295 Lso was also detected in several weed plants surrounding carrot and parsnip field

296 rapid elevation of serotonin, but they take several weeks to achieve therapeutic onset.

297 had emigrated to Canada from the Middle East several years earlier and had no medical history of note

298 citing advances have been made over the past several years in elucidating drug-induced changes at mol

299 and typically develop coronary heart disease several years later than men.

300 For several years, most studies have focused on pernicious a