ライフサイエンスコーパス: several-fold

1 her can induce human beta-cell proliferation several fold.

2 enabling the effective volume to be enlarged several fold.

3 rdia initiation, but instead increases it by several fold.

4 ions, even breaking the diffraction-limit by several fold.

5 uency required to induce spine plasticity by several fold.

6 mplex, prolonging the dissociation half-life several fold.

7 hereas staining for Lgr5 and Msi-1 increased several fold.

8 ites, which increased the Switching fraction several fold.

9 nd other organochlorine pesticides increased several-fold.

10 (2) increases the efficacy of such oligomers several-fold.

11 enic mice), the cellular responses increased several-fold.

12 expression of the endogenous G-CSF receptor several-fold.

13 hat express endothelial cell lineage markers several-fold.

14 although it increased p21(WAF1/Cip1) levels several-fold.

15 ion increases hypothalamic syndecan-3 levels several-fold.

16 s the number of effectively known structures several-fold.

17 e energy costs of terrestrial transport vary several-fold.

18 ing the resolution of any optical microscope several-fold.

19 we measured, with some sublines differing by several-fold.

20 -fold and the extension length was shortened several-fold.

21 ell population, increasing neuron production several-fold.

22 scattering efficiency, in some cases varying several-fold.

23 the sensitization of cancer cells to therapy several folds.

24 o ribose synthesis from glucose is decreased several fold 2 to 4 days after removal of thiamine from

25 pid increase in intracellular malonyl-CoA to several fold above control levels, whereas TOFA reduced

26 intracellular Ca2+ signals in cultured PAEC several fold above the basal level.

27 In female rats, concentrations of NKB several-fold above that of an animal 20 days into pregna

28 surface area of early visual cortices varies several fold across healthy adult humans and is genetica

29 Estimated CVD risk varied several-fold across Asia-Pacific risk regions.

30 m the wild-type alphabeta enzyme resulted in several-fold activation of the enzyme.

31 reduce light-field video processing times by several-fold, advancing the goal of real-time, scatterin

32 ication of this approach offers as much as a several-fold advantage in discovery probability relative

33 ular TGFBIp expression by HCECs is increased several fold after exposure to TGFB1.

34 act as a VEGF signaling inhibitor, increased several fold after introducing caHIF1alpha into epicardi

35 These autophagosomes also increased several-fold after autophagic stimulation.

36 Mitotic spindle length, for example, varies several-fold among cell types and among different organi

37 thetic nerve activity (SNA) at rest can vary several-fold among normotensive individuals with similar

38 s of proinflammatory cytokines were elevated several fold and intense vascular damage was observed.

39 heir flagellar adenylyl cyclase is activated several fold and preparation for cell fusion is initiate

40 rbohydrate consumption, fructose levels rise several fold and reach a concentration sufficient to act

41 ling indicated that BMP2-(PEO-HA)2 exists in several folded and extended conformations, depending on

42 fy the total carotenoids and chlorophylls in several folded and un-folded citrus essential oils to de

43 ependent factor VIIIa inactivation increased several-fold and correlated with an increased rate of cl

44 red to unwind a single fimbria was increased several-fold and the extension length was shortened seve

45 0 (CYP) 2E1 messenger RNA (mRNA) and protein several-fold, and enhanced expression has been associate

46 smoking increases the risk of developing IPF several-fold, as do other exposures such as metal-fume a

47 fluorescence intensity reversibly increased several-fold, as expected if the probe's chemical microe

48 ium enters and cytosolic calcium levels rise several-fold, as measured by fura-2 ratiometric analysis

49 was active at submicromolar concentrations, several-fold below those required for equivalent effects

50 ty of detecting uranyl ion by CdS-MAA-TU was several folds better (0.316 L/ mug) than that of CdS-MAA

51 ite neuronal and synaptic parameters varying several-fold between individual instantiations.

52 rase induction in many tissues, ranging from several-fold (brain) to >5000-fold (liver) after LPS or

53 of the human 24-hydroxylase gene was induced several fold by 1,25(OH)2D3 in normal human keratinocyte

54 mentally mediated brain disease is augmented several fold by lack of infrastructure, poor health and

55 der control conditions, it could be enhanced several fold by pharmacological or endogenous activation

56 vity towards non-CDK substrates is increased several-fold by T170 phosphorylation.

57 Synaptotagmin-2 expression was increased several-fold by the CaM knockdown, which accounted for t

58 Instability was enhanced several-fold by transcription in the forward or reverse

59 lambdaPP can be activated several-fold by various divalent metal ions, with Mn(2+)

60 experimental manipulations that change, over several fold, cell number or average cell size.

61 kin layers from OA modified NPS increased by several folds compared to unmodified NPS and control sol

62 lesions and the concentration of PAI-1 rises several fold, complex formation is a probable cause of t

63 This agent offers several-fold CT signal enhancement in vitro and in vivo

64 ted substrate to a chloroform vapour lead to several fold decrease of the baseline potential waves an

65 Western blots showed a several-fold difference in levels of PsbS protein betwee

66 the nature of the central spacer; less than several fold differences in affinity were observed when

67 Several-fold differences among accessions were found for

68 We identified several-fold differences in incidences of gastric adenoc

69 sitol-responsive UASINO sequences) decreased several fold during the first hour, after which expressi

70 Expression of HO1 increased several-fold during incubation of the cells for 72 h in

71 at the expression of CMO in leaves increased several-fold during salinization.

72 ations for a HBV-related diagnosis increased several-fold during the 1990s.

73 ive to FLT3 ligand, the levels of which rise several-fold during the course of chemotherapy.

74 ydraulic capacities of angiosperms escalated several-fold during the Cretaceous.

75 rtion of ischemic strokes and might multiply several-fold during the next decades.

76 of RNA corresponding to this cDNA increased several-fold during tomato ripening, and the amount of R

77 These mice had several-fold elevated Wnt16 expression in both trabecula

78 ons in the soma than in the neurite, despite several-fold elevation of Fmr1 mRNA levels.

79 stant amino-terminal 39-kDa core kinase with several-fold enhanced activity.

80 edly enhanced the sensitivity of biosensors (several folds enhancement without the need of tailored o

81 urnover number (TTN, 59204 mol mol(-1) ) and several-fold enhancement in the enzyme catalytic efficie

82 ces we find that heterochromatic regions are several-fold enriched for these operationally defined SA

83 anti-microRNA-195a oligonucleotide augmented several-fold ET-1-induced MIP-1beta expression.

84 There is a several-fold excess of 10-formyltetrahydrofolate dehydro

85 rounded cells are suddenly presented with a several-fold excess of cell surface whose area far excee

86 ion to address these limitations, offering a several-fold expanded three-dimensional field of view.

87 ust regenerative response that resulted in a several-fold expansion in the pool of surviving preOLs i

88 on of LAT-A induced dose- and time-dependent several-fold facility increases.

89 es not require a tag, and its elimination is several fold faster compared with standard promoter shut

90 The measurements and analysis show a several-fold faster synthesis of PI(4,5)P2 in sympatheti

91 lectrophoretically in ca. 6 micros, a period several-fold faster than was previously feasible using u

92 by recombinant target enzyme and underwent a several-fold fluorescence increase upon phosphorylation.

93 wash method that improved sensitivity up to several folds for a broad range of polar and (2)H-labele

94 NF kappa B binding activity increased several-fold from 2 to 12 hr, then gradually declined du

95 A several-fold greater counting efficiency is observed for

96 dult and as expected, expression of PCNA was several-fold greater in cerebral arteries of the 95-d fe

97 These responses were several-fold greater in femoral artery as compared to va

98 Using WT donor cells, ATM accumulation is several-fold greater in obese recipient mice compared wi

99 s of adult rat hippocampal formation (HF) is several-fold greater in their pellet than their supernat

100 to conventional methods, APC-ms facilitates several-fold greater polyclonal T-cell expansion and imp

101 he dyedron/scFv complex to brightness levels several-fold greater than that for single fluorescent pr

102 This binding is several-fold greater than that of a known MAR in the c-m

103 etrical and spans a large time range that is several-fold greater than the average peptide synthesis

104 bove a critical P:L ratio, which is at least several-fold greater than the value corresponding to the

105 d resulted in VEGF protein expression levels several-fold greater than those produced by the natural

106 on of deoxyribosylthymine (dT) occurred with several-fold-greater efficiency opposite the 3' G compar

107 eine-rich Bowman-Birk protease inhibitor was several fold higher in transgenic soybean plants when co

108 hed for ERalpha-positive cells and expressed several fold higher levels of the ERalpha, p21(CIP1) and

109 Further, FQs had several fold higher overall concentrations in feces than

110 at 10,000 IU/d produced genomic alterations several fold higher than 4,000 IU/d even without further

111 DDE concentration was 25 mg/L (range 3-178)-several fold higher than current US concentrations.

112 s for transfusion medicine are appropriately several fold higher than for the rest of clinical medici

113 increased faster and reached maximal levels several fold higher than in the macrophage-poor WT lesio

114 no effect on the locomotor activity at doses several fold higher than its efficacious dose.

115 id exhibited reporter gene expression levels several fold higher than plasmid or NPs without S/MARs.

116 ated concentration in the range of 20 ng/ml, several fold higher than that of soluble Abeta.

117 ood-brain barrier, and is non-toxic at doses several fold higher than the efficacious dose.

118 results showed that peptide analogue 22 had several fold higher uptake by the TNBC cells compared to

119 solar energy into hydrogen at rates that are several fold higher, compared with any previously descri

120 igh in the PC3 prostate cancer cell line and several folds higher in a metastatic clone of PC3 (PC3M)

121 s not affect the locomotor activity at doses several folds higher than its efficacy dose.

122 levated and ERK is constitutively activated, several folds higher than that in parental cells.

123 complications, and sepsis, all of which were several-fold higher after sepsis versus after matched no

124 were detectably elevated by 8 hours and were several-fold higher by 24 hours after treatment.

125 s low as 0.16 muM and negligible toxicity at several-fold higher concentrations.

126 t cells on the somata of pyramidal cells had several-fold higher density of alpha1 subunit-containing

127 LP had several-fold higher expression and showed larger current

128 PK activity and PI3-kinase activity were all several-fold higher in cells seeded on fibronectin or in

129 antiretroviral therapy (cART) initiation are several-fold higher in resource-limited countries than i

130 ans, the overall frequency of DCV at MYOC is several-fold higher in the general population of African

131 tandard diet, hepatic iron concentration was several-fold higher in the homozygous Tfr2(Y245X) mutant

132 xperimental groups; however, its levels were several-fold higher in the Mta1(+/+) mice than in infect

133 NF1 editing occurs in normal tissue but was several-fold higher in tumors.

134 raries averaging 14.0 crossovers per gene, a several-fold higher level of recombination than observed

135 However, this mutant expressed several-fold higher levels of plcH message than strain P

136 The one nonresponder exhibited several-fold higher plasma and brain fluvoxamine levels.

137 and two mutants were identified that express several-fold higher protein levels compared with the wil

138 njected dose per gram of tissue [%ID/g]) was several-fold higher than 125I-VIP (0.06 %ID/g) at 24 h a

139 are shown to mis-segregate in cells at rates several-fold higher than chromosomes with CENP-B-contain

140 pecific incidence of Alzheimer's disease was several-fold higher than corresponding figures that were

141 as message for link protein and lumican were several-fold higher than expected by their measured prot

142 ranscription in response to levels of Mn(II) several-fold higher than required for repression of impo

143 nce of Lyme disease in Westchester County is several-fold higher than suggested by the current passiv

144 elicit cytosolic Ca(2+) transients that are several-fold higher than the sum of those driven by each

145 in gingival crevicular fluid (GCF) that are several-fold higher than their levels in serum.

146 plants, dcl1 RNA forms accumulated to levels several-fold higher than those in DCL1 plants.

147 c bond results in large potency enhancements several-fold higher than those of corresponding unsubsti

148 we report that at concentrations of spermine several-fold higher the MT bundles (B(MT)) quickly becom

149 N2-fixation rates at these two stations were several-fold higher when scaled to other productivity me

150 This mechanism results in several-fold-higher kink density, a faster rate of cryst

151 of NgR (NgR(DN)) increased axon regeneration several-fold; however, when the growth program of RGCs w

152 gs of up to 40 wt% or 3.8 at.%, representing several-fold improvements compared to benchmarks in the

153 thyl-auristatin-F to HeLa cells is increased several fold in presence of Ca(2+).

154 l of glucose transporter 4 (GLUT4) decreased several fold in the adipose tissue of WT mice fed a HF/H

155 the recovery of the initial state is slowed several fold in Y83N.

156 antigens, draining lymph nodes (LNs) expand several folds in size, but the fate and role of the FRC

157 ma components decreased DNA binding to glass several-fold in a concentration-dependent manner.

158 capable of inhibiting LTP and is upregulated several-fold in brain tissue, serum, and CSF of Alzheime

159 e expression from the plasmid was diminished several-fold in cells infected by the evolved phages.

160 ly low voltages, lowering breakdown voltages several-fold in comparison to traditional electrodes, an

161 palmitoyl-CoA oxidase activity was increased several-fold in developing seeds expressing MCTE.

162 (wt)-EpoR, EpoR-HM activity was compromised several-fold in each context when Epo was limited to phy

163 Transplanted cell engraftment improved by several-fold in ETN-treated animals.

164 evels of JAM-A, occludin, cingulin, and ZO-1 several-fold in glomeruli and loosened their attachment

165 cer+tracee) Phe concentrations; errors up to several-fold in magnitude were noted when the same appro

166 m-dependent potassium currents are increased several-fold in neurons bearing a homozygous P924L mutat

167 ressive GN, Notch3 expression was induced by several-fold in podocytes concurrently with disease prog

168 ing size, and breeding failure will increase several-fold in Southern Yellow-billed Hornbills (Tockus

169 ra copy of chromosome 21 and overexpress APP several-fold in the brain, develop the pathology of AD i

170 Mitochondrial NADH fluorescence is enhanced several-fold in the matrix through extended fluorescence

171 (CE) and triacylglycerol levels are elevated several-fold in the spinal cord GM of male sporadic ALS

172 AGEs were increased several-fold in transgenic compared with control lenses.

173 he activity of APE1/Ref-1 abruptly increases several-fold in various human cancers.

174 directly enhance microtubule growth rate by several-fold in vitro.

175 nce of the prioritized ceRNA interactions by several folds, in terms of precision and recall.

176 e report that coculture with NK cells causes several fold increase in IL-12 production by Toxoplasma

177 the 200 bp to 1100 bp size range, which is a several fold increase in marker density as compared to t

178 Several folds increase in Eulerian velocity fluctuation

179 w developments in MFCs which has resulted in several-fold increase in achievable power density.

180 Surprisingly, despite the several-fold increase in CAA levels, APP/PS1;Clu(-/-) mi

181 The mechanism involves a several-fold increase in cyclic AMP (cAMP) generation an

182 s respond to an amphetamine challenge with a several-fold increase in dopamine release over a 4-hour

183 larity appears to have been accompanied by a several-fold increase in gene number, the invertebrates

184 e metabolism in these animals demonstrated a several-fold increase in hepatic very-low density lipopr

185 All mutants showed a several-fold increase in KMgATP, much larger increases i

186 muscle-specific expression of BCL2 led to a several-fold increase in lifespan and an increased growt

187 Ca2+ increase that was dose dependent and a several-fold increase in Pi.

188 Loss of VHR also caused a several-fold increase in serum-induced activation of its

189 In these experiments, GMAP demonstrated a several-fold increase in speed over existing programs.

190 ry of a central pattern generator, such as a several-fold increase in synaptic strength, can sometime

191 assay, Cx43 expression was associated with a several-fold increase in the competence of glioma cells

192 th of these genetic interventions produced a several-fold increase in the lifespan of Lama2(-/-) mice

193 ut neurological defects is associated with a several-fold increase in the risk of sinusitis, laryngit

194 l membrane depolarization concomitant with a several-fold increase of transmembrane currents.

195 d anti-miR-199a-5p oligonucleotides led to a several fold increased FLAP mRNA and protein expression.

196 This resulted in sustained, several-fold increased expression of CRRY in the RPE, wh

197 Forskolin increased nNOS mRNA levels several fold, increased production of nitric oxide, and

198 trated large behavioral changes (i.e., up to several fold increases in error rate) with relatively lo

199 tion of inhibitor of kappaB kinase-alpha and several fold increases in NF-kappaB-inducing kinase and

200 (LSEC) derived from ethanol-fed rats showed several fold increases in the mRNA expression of endothe

201 f traditional Dynamic Time Warping, allowing several-fold increases in computation speed.

202 imulated at specific frequencies, generating several-fold increases in motion amplitude.

203 ors generate similar firing patterns despite several-fold increases in size between juveniles and adu

204 vements in fine-mapping accuracy (e.g. up to several-fold increases in the area under the precision-r

205 Here we report that I/R triggers several-fold increases in the hepatic levels of the endo

206 Finally, we documented several-fold increases in the uptake of [(3)H]choline in

207 ansfected HeLa and HEK293 cells demonstrated several-fold increases in the uptake of various bacteria

208 ever, the data generated by these arrays are several-fold larger than data from earlier platforms, cr

209 DAP firing rates were several-fold larger than somatic rates.

210 al phenotypes in zebrafish is expected to be several-fold larger than the one for which we have obser

211 ng a value of approximately 85 m/N, which is several-fold larger than the thick-filament compliance d

212 cells increased the expression of periostin several-fold, leading to subsequent loss of the epitheli

213 acZ reporter gene in wild-type yeast but was several-fold less effective in delta trr1 yeast lacking

214 were compared, the mucoid cells were cleared several-fold less efficiently than the parental nonmucoi

215 w that the ED pathway is expected to require several-fold less enzymatic protein to achieve the same

216 to give an equivalent level of necrosis was several fold lower in fibroblasts than in keratinocytes.

217 ere all hypersensitive to Cd and accumulated several fold lower levels of As, Cd, and Zn than wildtyp

218 induced" levels of LIP in keratinocytes were several fold lower than in fibroblasts.

219 subtype and C-subtype clinical isolates were several folds lower than those of 1.

220 adf9-1showed a several-fold lower expression of FLOWERING LOCUS C (FLC)

221 This capacity for qE was several-fold lower in RNAi plants and significantly high

222 ed hTR, although enzyme activity levels were several-fold lower than in the corresponding invasive tu

223 Stu1p levels in stu1-5 cells are several-fold lower than the levels in wild-type cells an

224 roximately 23 pN at high filling, which is a several-fold lower value than was previously estimated u

225 ation size of this species is inferred to be several-fold lower.

226 re formation fits well into the framework of several folding mechanisms and confirms features that up

227 he advantages of iPF2alpha-VI are that it is several fold more abundant in urine than iPF2alpha-III,

228 ical experiments, its efficiency is enhanced several fold more by optimizing enzymatic stoichiometry

229 -4(1H)-imines as dual-stage antiplasmodials, several-fold more active than primaquine in vitro agains

230 It is shown that copy-up variants are several-fold more active than wt pi35.0 in replication.

231 White people in the United States are several-fold more affected by esophageal adenocarcinoma

232 sidues after incubation with mitotic lysates several-fold more extensively than after incubation with

233 ast to Drd2 (+/+) mice, in which dopamine is several-fold more potent at neurons in the nucleus accum

234 Further, candidate compounds exhibit several-fold more potent MCT1 inhibition properties as d

235 ll response time of approximately 0.05 s was several-fold more rapid than the motor response time of

236 pared with patient tumors, whereas CWR91 was several-fold more sensitive; and (d) CWR22, CWR22R and p

237 In general, the MMCIA has at least several-fold more sensitivity than the conventional enzy

238 Cell lines proficient in MMR exhibited several-fold more sensitivity to killing than cell lines

239 more rapidly, the mutant enzymes dissociated several-fold more slowly than the wild type.

240 IgE and Ag, ASK cells produced and secreted several-fold more TNF-alpha and IL-2 than EL cells.

241 Circulating viral titers increased several-fold over baseline levels during posttransplant

242 C-PLC secreted into infected cells increased several-fold over controls within 5 min of a decrease in

243 , we find potential to increase productivity several-fold over current levels.

244 oise ratio, and number of neurons observable several-fold over previously published fully genetically

245 The several-fold overexpression of Hsp110 in motor neurons o

246 ion during repetitive activity, with a large several fold postsynaptic response increase.

247 ve isoforms, but the molecular basis for the several-fold range in GPVI levels of human platelets rem

248 We show that over a several-fold range of both of these parameters, and over

249 It is also used by several fold-recognition consensus methods and meta-serv

250 Compared with sequence comparison and several fold-recognition methods, the method demonstrate

251 compared with unmodified FVIII, resulting in several-fold reduced cellular uptake.

252 e flanked by insulator elements leading to a several fold reduction in LMO2 expression.

253 thesis and degradation are unaffected by the several fold reduction in vigilin levels early in siRNA

254 ithin a 55 bp conserved domain each caused a several-fold reduction in mature pollen expression.

255 Here we demonstrate a several-fold reduction in temperature(6,11-13), bringing

256 h MIS and demonstrated that it can lead to a several-fold reduction in testosterone in serum and in t

257 Recombinant mutant calmodulins exhibited several-fold reductions in calcium binding affinity.

258 ibody-dependent cellular cytotoxicity (ADCC) several fold relative to the anti-HM1.24 IgG1 analog aga

259 d trans-activation of the reporter construct several-fold relative to cells treated with TCDD alone.

260 Several-fold repression of OC-luciferase constructs was

261 ve terminals beyond the previously reported, several-fold, residual calcium-driven modulation that pe

262 ell-specific profiling increases sensitivity several-fold, revealing highly localized regulation of t

263 Several folding scenarios can be anticipated by consider

264 e integration efficiency of transforming DNA several-fold, similar to the results for CHO cells.

265 s of Hg to the North Atlantic have decreased several-fold since the 1970s while inputs to the North P

266 The average rate of unwinding was several-fold slower than the PcrA translocation rate on

267 cific ones, are transcriptionally suppressed several-fold specifically in the Drosophila male germlin

268 telet-leukocyte aggregates and resulted in a several-fold systemic increase in leukocyte rolling 2 to

269 protein was transiently expressed at levels several fold that of the endogenous proteins.

270 Insulin increased by several fold the observed frequencies, but not velocitie

271 ethyl-cytosine(s) were de novo methylated at several fold the rates of non-methylated controls.

272 The ensuing inside-out signaling increases several-fold the affinity and avidity of alphaIIb/beta3

273 , the vascular cache of FIX bound to Col4 is several-fold the FIX level measured in plasma.

274 ncentration or using a mutant RNAP increases several-fold the percent of revertants containing MCMs.

275 Cofilin inhibited several-fold the rate of interstrand disulfide cross-lin

276 end regions decreases total recombinants by several fold, the frequency of recombinants with correct

277 ed the rate of oxidative base damage and, by several fold, the lesion frequency in mtDNA.

278 t up to achieve intracellular concentrations several-fold those of GSH.

279 racy of previous error-correction methods by several folds to an order of magnitude, depending on the

280 L1 insertions reduced transcript levels from several-fold to more than 10-fold.

281 We report simulations of several folding trajectories of NTL9(1-39), a protein wh

282 tion of functional channels and gj increased several fold under an exposure to SCCAs, or during reduc

283 Finally, several folding/unfolding trajectories give a systematic

284 the amplitude of unitary EPSCs can increase several-fold, unlike what is observed when release proba

285 Associated with this process is the several-fold up-regulation of the tumor suppressor gene

286 nd, the catalytic ability of SSI was reduced several-fold using these glucans with extended chain len

287 ites, with the differences ranging from only several fold weaker binding to no detectable interaction

288 (cisplatin and gamma-irradiation) increased several folds when cells were forced to grow in anchorag

289 iscosity of blood is observed to increase by several folds when compared to non-stenosed vessels.

290 of AS mRNA increased in T. versicolor roots several-fold when seedlings were exposed to exudate obta

291 ecreases its affinity for the PDZ domains by several fold, which would free PDZ domains for occupancy

292 er of the peptide increased elongation rates several-fold, while insertion of Pro-Pro dramatically sl

293 ried tissue Tr288 transcript levels increase several-fold, while the relatively high amount of Tr288

294 y over all folds and nearly 100% accuracy on several folds with distinctive conserved structural feat

295 CoA carboxylase (ACC) transcript is enhanced several-fold with a concomitant increase in the tissue l

296 s and improved data increases sensitivity by several fold, with the greatest impact in challenging re

297 levels in leaves of tomato plants increased several fold within 2 hr after supplying the polypeptide

298 ithm can further speed up the calculation by several folds without loss of accuracy.

299 ed the low NRSF levels in mature hippocampus several fold yet surprisingly, provoked repression of on

300 improved treatment tolerability and efficacy several fold, yet with intersubject variability.