ライフサイエンスコーパス: severe

1 of sting-induced reactions are classified as severe.

2 he evolutionarily conserved microtubule (MT)-severing AAA-ATPase enzyme Katanin is emerging as a crit

3 for more than a month started complaining of severe abdominal pain.

4 istent with a single cofilin having filament-severing activity.

5 y occurred in 48 of 116 patients (41.4%) and severe acute kidney injury in 32 of 116 (27.6%) patients

6 Severe acute malnutrition (SAM) is the most serious form

7 We induced severe acute pancreatitis by partial duct ligation with

8 thogenicity-but also aided in the control-of severe acute respiratory syndrome (SARS) in 2003(5).

9 Dysregulated immunothrombosis in severe acute respiratory syndrome corona virus 2 pneumon

10 Population-based serosurveys measuring anti-severe acute respiratory syndrome coronavirus 2 (anti-SA

11 members responded following the emergence of severe acute respiratory syndrome coronavirus 2 (SARS-Co

12 The severe acute respiratory syndrome coronavirus 2 (SARS-Co

13 The rapid spread of severe acute respiratory syndrome coronavirus 2 (SARS-Co

14 leic acid amplification for the detection of severe acute respiratory syndrome coronavirus 2 (SARS-Co

15 primary tumour subtype, age, and sex and on severe acute respiratory syndrome coronavirus 2 (SARS-Co

16 This pathogen, named severe acute respiratory syndrome coronavirus 2 (SARS-Co

17 , neutralizing monoclonal antibodies against severe acute respiratory syndrome coronavirus 2 (SARS-Co

18 fy the source and number of introductions of severe acute respiratory syndrome coronavirus 2 (SARS-Co

19 Severe acute respiratory syndrome coronavirus 2 (SARS-Co

20 d detection of individuals who may carry the severe acute respiratory syndrome coronavirus 2 (SARS-Co

21 Preliminary data from severe acute respiratory syndrome coronavirus 2 (SARS-Co

22 ns of identifying acute infections caused by severe acute respiratory syndrome coronavirus 2 (SARS-Co

23 Antibody-based drugs and vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-Co

24 irus disease 2019 (COVID-19) or detection of severe acute respiratory syndrome coronavirus 2 (SARS-Co

25 oronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-Co

26 a concern for healthcare workers during the severe acute respiratory syndrome coronavirus 2 (SARS-Co

27 when, where, and how the earliest sustained severe acute respiratory syndrome coronavirus 2 (SARS-Co

28 A safe and effective vaccine for severe acute respiratory syndrome coronavirus 2 (SARS-Co

29 from the collusion between a new pandemic of severe acute respiratory syndrome coronavirus 2 (SARS-Co

30 The causative agent, severe acute respiratory syndrome coronavirus 2 (SARS-Co

31 Tests for severe acute respiratory syndrome coronavirus 2 (SARS-Co

32 Severe acute respiratory syndrome coronavirus 2 (SARS-Co

33 ies some risk for exposure to infection with severe acute respiratory syndrome coronavirus 2 during t

34 s, and dysarthria with positive findings for severe acute respiratory syndrome coronavirus 2 from nas

35 erlying conditions have been associated with severe acute respiratory syndrome coronavirus 2 illness,

36 CU for coronavirus disease 2019 out of 1,788 severe acute respiratory syndrome coronavirus 2 positive

37 mboembolism events in patients infected with severe acute respiratory syndrome coronavirus 2 requirin

38 rapidly expanding global pandemic caused by severe acute respiratory syndrome coronavirus 2, resulti

39 ff and subsequent family members exposure to severe acute respiratory syndrome coronavirus 2.

40 spectrum activity against viruses, including severe acute respiratory syndrome coronavirus, human imm

41 notic virus that caused the 2002 outbreak of severe acute respiratory syndrome, including the system

42 mbotic, and procoagulant responses following severe acute respiratory syndrome-coronavirus-2 (SARS-Co

43 The inflammatory response to severe acute respiratory syndrome-related coronavirus 2

44 sus fluconazole in subjects with moderate-to-severe acute VVC.

45 nd nonlesional) with early-onset moderate-to-severe AD (<=6 months) and 17 healthy controls.

46 logy in serum samples from 146 patients with severe AD (median Eczema Area and Severity Index = 28.3;

47 he CHD8 and target groups that included less severe adaptive deficits in communication skills, simila

48 ssing UPEC strains have been associated with severe advanced kidney pathologies, such as cystitis and

49 major decreases in LOS had a higher risk of severe adverse events [1.22 (1.11-1.34)] and death [1.17

50 al efficacy, there is also the potential for severe adverse events, including cytokine release syndro

51 the 250-mug dose group reported one or more severe adverse events.

52 owth restriction (FGR) and pre-eclampsia are severe, adverse pregnancy outcomes.

53 79] for AKI, 0.79 (95% CI, 0.74 to 0.83) for severe AKI, and 0.81 (95% CI, 0.77 to 0.86) for neonatal

54 ed IGFALS as a useful biomarker for moderate-severe allergic asthma.

55 ns can be asymptomatic, they often result in severe and chronic diseases.

56 nt of the original SSIS technique to address severe and extensive small bowel Crohn's disease present

57 ons and supernumerary copy variants, lead to severe and fatal disease.

58 Rabies virus (RABV) causes a severe and fatal neurological disease, but morbidity is

59 Severe and fatal SFTS presents as a hemorrhagic fever ch

60 Perioperative stroke is one of the most severe and feared complications of cardiac surgery.

61 extreme wet episodes, which are becoming as severe and frequent as droughts, are overlooked and thei

62 easons we do not understand, malaria becomes severe and life threatening.

63 nts in the ocean, marine heatwaves, can have severe and long-lasting impacts on marine ecosystems, fi

64 Subsequently, a severe and novel pediatric disorder termed multisystem i

65 ase (SCD) are severe monogenic diseases with severe and potentially life-threatening manifestations.

66 y attacks of CNS inflammation that are often severe and predominantly affect the spinal cord and opti

67 ings, temporary off-label use of Tpo-RAs for severe and/or refractory ITP during pregnancy seems safe

68 an 5 years of age who had been admitted with severe anemia.

69 iographic findings in low-risk patients with severe aortic stenosis after surgical aortic valve repla

70 In patients with severe aortic stenosis undergoing TAVR, even with baseli

71 (TAVR) to low-risk patients with symptomatic severe aortic stenosis.

72 Among patients with COVID-19 and moderate or severe ARDS, use of intravenous dexamethasone plus stand

73 Compared to NF, LF severe AS had higher LV stiffness indices (>0.11 ml(-1)

74 idation testing in independent children with severe asthma (n = 21) and mild/moderate asthma (n = 154

75 creased type 2 inflammation in patients with severe asthma and those with frequent exacerbations.

76 hage numbers were significantly decreased in severe asthma compared to mild-moderate asthma and healt

77 mprovement in the management of ICU-admitted severe asthma episodes.

78 bjects (14.7%; 95% CI, 11%-19.1%) reported a severe asthma exacerbation in the 4 weeks after immuniza

79 librium with rs56151658 were associated with severe asthma exacerbations at a P value of .01 or less

80 and probabilistic causal methods to identify severe asthma genes and their master regulators.

81 Severe asthma patients with high blood eosinophils or lo

82 In the Severe Asthma Research Program (SARP) III cohort, we det

83 g young children with adrenal dysfunction or severe asthma that are treated with high doses of inhale

84 atient clustering stability in patients with severe asthma.

85 ion (both with a strong gradient); diabetes; severe asthma; and various other medical conditions.

86 and the mechanisms explaining the paradox of severe asthmatic children, whom when clinically stable c

87 nd well tolerated in adults with moderate-to-severe atopic dermatitis in a phase 2b trial.

88 hout the brain, pathological findings reveal severe atrophy of cerebellar cortex in SCA1 patients.

89 This results in less severe autonomic dysreflexia, a real-time gauge of sympa

90 s highlight the impending risk of sudden and severe biodiversity losses from climate change and provi

91 somes, and single-agent controls and reduces severe BTZ-associated side effects.

92 We studied the effects of severe bunch thinning on the accumulation of primary met

93 ts on M. smegmatis growth range from mild to severe, but many cause irreversible loss of viability.

94 after complete loss of his allograft due to severe CAMR.

95 em and they may prove beneficial in the most severe cases by reducing the risk of losing the globe al

96 accelerates development of the skull and, in severe cases, might lead to craniosynostosis with neurol

97 hematopoietic stem cell failure in the most severe cases.

98 Preperimetric, mild, moderate, and severe categories included 41, 89, 97, and 63 eyes, resp

99 idaxomicin for nonsevere CDI, vancomycin for severe CDI, fidaxomicin for first recurrence, and FMT fo

100 y the new SARS-CoV-2 coronavirus has imposed severe challenges on laboratories in their effort to ach

101 d structures(1,2), which are associated with severe chronic inflammatory diseases that span several o

102 Its malfunction causes the severe ciliopathy Bardet-Biedl syndrome (BBS).

103 els were detected in animals euthanized with severe clinical disease compared with mock-infected cont

104 ures (15.4% vs 45.1%; P = .005) and had less severe clinical presentations (median Pitt score, 0 [int

105 effect noncoding variants and/or by rare but severe coding variants, many de novo.

106 ose level, <54 mg per deciliter) or level 3 (severe cognitive impairment) were low (icodec group, 0.5

107 ugh Abeta levels become abnormal long before severe cognitive impairments appear, increasing evidence

108 ibroblasts and in aggressive tumor growth in severe combined immunodeficiency mice.

109 ariants in AK2 cause reticular dysgenesis, a severe combined immunodeficiency with agranulocytosis, l

110 vivo binding characteristics were studied in severe combined immunodeficient (SCID) mice inoculated w

111 Diabetic ketoacidosis (DKA), a severe complication of diabetes mellitus with potentiall

112 Fewer severe complications (Clavien-Dindo grade IIIb or more)

113 kidney disease patients presented frequently severe complications requiring critical care that induce

114 Neural tube defects (NTDs) are a group of severe congenital malformations caused by a failure of n

115 edispose aged mice toward the development of severe corneal epithelial disease after exposure to a dr

116 ing altered susceptibility and propensity to severe Coronavirus disease 2019 (COVID-19) disease in at

117 tients with moderate COVID-19, patients with severe COVID-19 had higher peak white blood cell counts

118 Remdesivir is efficacious for severe COVID-19 in adults, but data in pregnant women ar

119 Severe COVID-19 infection was noted in 74 (37.6%) patien

120 Severe COVID-19 is rare in previously healthy individual

121 Conversely, patients with severe COVID-19 showed a highly significant increase of

122 y, we included two groups of inpatients with severe COVID-19 who had been discharged or died in Jin Y

123 chemotactic receptor CCR2 is associated with severe COVID-19.

124 steroid therapy in patients with moderate to severe COVID-19.

125 When severe, COVID-19 is a systemic illness characterized by

126 Patients with severe CRS may develop capillary leak syndrome and disse

127 ratory symptoms, some patients present other severe damage such as cardiovascular, renal and liver in

128 eath (adjusted hazard ratio for moderate and severe degrees of malnutrition, respectively: 2.02 [95%

129 toms, ranging from classical dengue fever to severe dengue hemorrhagic fever or dengue shock syndrome

130 rostatus, serotype, hospitalised dengue, and severe dengue) in the first 17 months.

131 ith increased inflammatory proteins and more severe depression but differed in terms of myeloid and l

132 Severe developmental errors in E- embryos were character

133 Kindlin-2 and deleting its expression causes severe diabetes-like phenotypes without markedly causing

134 Duchenne muscular dystrophy (DMD) causes severe disability and death of young men because of prog

135 Challenges to the prevention of severe disease after virus infection include both a pauc

136 ients with hypertension or with mortality or severe disease among patients diagnosed as having COVID-

137 d infection with ribotype 027 associate with severe disease and adverse outcomes.

138 s (aged >=70 years) are at increased risk of severe disease and death if they develop COVID-19 and ar

139 Patients present with severe disease at a relatively early age and most (67%)

140 -infected pediatric patients correlates with severe disease development.

141 eas the profiles of those with who developed severe disease had elevated levels of all four signature

142 Severe disease has been associated with changes in perip

143 SARS-CoV-2 MA caused more severe disease in aged mice, and exhibited more clinical

144 h severe LF.IMPORTANCE Lassa fever may cause severe disease in humans, in particular in areas of ende

145 H5 A/goose/Guangdong/1/96 lineage can cause severe disease in poultry and wild birds, and occasional

146 um and the causative agent of melioidosis, a severe disease in tropical regions.

147 Fusarium head blight (FHB) is a severe disease of wheat (Triticum aestivum L.).

148 verall, and possibly better efficacy in more severe disease warrant further study.

149 m COVID-19 (28 with mild disease and 14 with severe disease) and 16 unexposed donors, using interfero

150 sease, 17 with moderate disease, and 24 with severe disease) and 20 healthy subjects.

151 y enterovirus A71 (EV-A71), presents mild to severe disease, and sometimes fatal neurological and res

152 oidosis may be an additional risk factor for severe disease.

153 olar lavage fluid mitochondrial DNA and more severe disease.

154 VID-19) and (2) risk factors predisposing to severe disease/mortality in the general population also

155 with compromised immune systems can develop severe disseminated disease.

156 Our work shows that severe disturbances caused by major tropical hurricanes

157 s of water deficits (e.g., mild, moderate or severe drought) remain elusive.

158 use of autologous serum-based eye drops for severe dry eye disease and 4 studies of persistent epith

159 efficacy of an EBV-specific vaccine or treat severe EBV infection and pathological consequences in im

160 th the strongest associations in people with severe eczema (compared with those without) for spinal (

161 The most severe effects were found with 300 mug/g b.w. of BrdU.

162 -expression of Brg1, in conjunction with the severe endogenous proinflammatory environment, can conve

163 dges of extracellular matrix that ligate the severed ends of the spinal cord.

164 3 (34.4%) in the placebo group had 1 or more severe exacerbations.

165 pectrum has been described, with potentially severe extracutaneous manifestations, morbidity and mort

166 e development of coma and lactic acidosis in severe falciparum malaria.

167 4) of 2420 families experienced moderate and severe food insecurity, respectively.

168 s in the different mouse strains, being most severe for C57BL/6NTac and C57BL/6J, less so for C57BL/6

169 The most severe form is non-obstructive azoospermia (NOA), which

170 sychosis is toxic or that it reflects a more severe form of schizophrenia.

171 iratory distress syndrome (ARDS) in the most severe form, while children are largely spared from resp

172 o 11-cis-retinal are associated with mild to severe forms of retinal dystrophy.

173 commonly present with high lethality in the severe forms of the disease.

174 perspective, simply reflect milder and more severe forms of the same diathesis.

175 n its management and the outcome of the most severe forms requiring ICU admission.

176 a of the genus Shigella cause shigellosis, a severe gastrointestinal disease that is a major cause of

177 a larger impact on reliability in eyes with severe glaucoma (-1.25 per 1-point decrease in SS; P < 0

178 .0; mild, 5.0-14.9; moderate, 15.0-29.9; and severe, >=30.0) and defined incident CKD (stage 3 or hig

179 ore, the reduced DRP load resulted in a less severe HAB than predicted based on discharge volume.

180 lobally are at risk of suspension due to the severe health system constraints and physical distancing

181 ab in patients with homozygous FH (HoFH) and severe heterozygous FH (HeFH).

182 nistration for the management of moderate to severe hidradenitis suppurativa.

183 immunocompetent adult with asthma developed severe human metapneumovirus (HMPV) illness complicated

184 8% [1:14]) among 17,728 unique subjects with severe hypercholesterolemia (920 patients with FH) on th

185 nce with late failure of insulin production, severe hyperglycemia/diabetes, lipodystrophy, hepatostea

186 impair triglyceride hydrolysis, resulting in severe hypertriglyceridemia.

187 rons detect glucose fluctuations and prevent severe hypoglycemia, but mechanisms mediating functions

188 Fewer and less severe hypoglycemic episodes occurred in the traditional

189 r of 44 (55%) patients developed moderate to severe hypophosphataemia (serum phosphate < 0.6 mmol/L).

190 Compared with milder symptoms, severe IBS-D was associated with increased medication us

191 Patients with granuloma or moderate-severe ileitis on biopsy were significantly associated w

192 esent an opportunity to substantially reduce severe illness and death among children worldwide.

193 cillary role in the management of those with severe illness.

194 e following RSV infection that leads to more severe immunopathology.

195 e for complicated infection (eg, abscess) or severe immunosuppression.

196 nt, 33% had moderate impairment, and 29% had severe impairment.

197 an acute febrile illness, 5-20% progress to severe infection associated with significant morbidity a

198 ls of IL-27 predispose neonatal mice to more severe infection during Gram-negative sepsis.

199 gistic regression analysis, risk factors for severe infection included pre-existing renal disease (od

200 d, uninfected [HEU]) are more susceptible to severe infection than HIV-unexposed, uninfected (HUU) ch

201 Severe infections induce hyperinflammatory responses tha

202 une dysfunction that predisposes the host to severe infections with unrelated pathogens.

203 eral other forms of epilepsy associated with severe intellectual disability.

204 audication) randomized patients with mild-to-severe intermittent claudication to either revasculariza

205 red to wild-type (WT) mice evidenced by more severe intestinal inflammation and impaired bacterial cl

206 With severe ion depletion gradients in the electrolyte during

207 with advanced kidney disease and moderate or severe ischemia on stress testing to be treated with an

208 pro-inflammatory genes for the moderate and severe isolates.

209 of extramarital sex are associated with more severe jealous response.

210 nsitivity and specificity of differentiating severe LATE-NC from FTLD-TDP cases with blind evaluation

211 city to inflamed tissues are associated with severe LF.IMPORTANCE Lassa fever may cause severe diseas

212 rategies to Open Occluded Coronary Arteries) severe/life-threatening/moderate and TIMI (Thrombolysis

213 The existing approaches may each have some severe limitations.

214 was used to estimate hazard ratios (HRs) for severe liver disease at 5, 10, and a maximum follow-up t

215 Studies were included that reported severe liver disease outcomes (defined as liver cirrhosi

216 often have chronic respiratory symptoms and severe lung function impairment, and an increased risk o

217 ary function and reduce lung viral loads and severe lung pathology.

218 usion thresholds among African children with severe malaria complicated by these factors.

219 n of submicroscopic malaria and diagnosis of severe malaria.

220 The end-Permian mass extinction was the most severe mass extinction event of the Phanerozoic and was

221 The higher mortality rates in people with severe mental illness (SMI) may be partly due to inadequ

222 patients had neonatal/early-onset diabetes, severe microcephaly, and epilepsy.

223 emia (TDT) and sickle cell disease (SCD) are severe monogenic diseases with severe and potentially li

224 sease characterized by joint destruction and severe morbidity.

225 erials with various body tissues may produce severe nanotoxicity of different organs including the he

226 Affected subjects exhibit signs of severe neurological defects.

227 e widespread transcriptional alterations and severe neurological dysfunction than MeCP2 loss.

228 salvage purine pathway, is characterized by severe neurological manifestations and uric acid overpro

229 erneurons are implicated in the pathology of severe neuropsychiatric disorders, for which effective t

230 tients with mild NMDCCC and 15 patients with severe NMDCCC, the protocol provided higher signal-to-no

231 oderate nonproliferative DR (NPDR; n = 125), severe NPDR (n = 20), and proliferative DR (PDR; n = 72)

232 Severe obesity is characterized by specific additional c

233 besity, but fewer than 0.1% of Veterans with severe obesity undergo it.

234 fective weight loss option for Veterans with severe obesity, but fewer than 0.1% of Veterans with sev

235 tests and then classified as having either a severe or a mild phenotype.

236 tion was not significantly associated with a severe or critical COVID-19 event (HR, 1.10; 95% CI, 0.7

237 nted outside of pregnancy and categorized as severe or nonsevere.

238 The participants were classified as non-severe or severe periodontitis.

239 of heart failure (HF) patients with moderate-severe or severe secondary mitral regurgitation with tra

240 it is well established that EBOV results in severe organ damage, our understanding of tissue injury

241 Globally, the risk of severe outcomes associated with COVID-19 has consistentl

242 navirus disease-19 (COVID-19) and developing severe outcomes, but current data are conflicting.

243 parison to the other two MS severity groups (severe: p = 0.001, moderate: p = 0.02).

244 Strikingly, severe pancreatic atrophy accompanied tumor progression

245 WON is a common consequence of severe pancreatitis and typically occurs 3 to 5 weeks af

246 One patient had severe PAP after long-term unilateral PGA exposure.

247 aortic root injury (p < 0.001), moderate-to-severe paravalvular regurgitation (p = 0.002), and 30-da

248 of tRNA modifications frequently results in severe pathological consequences.

249 articipants were classified as non-severe or severe periodontitis.

250 he arterial wall and aortic sinus induced by severe periodontitis.

251 icant association between sleep duration and severe periodontitis.

252 We recruited 156 children with severe persistent asthma and controls for nasal transcri

253 potential alternative for management of this severe plant pathogen, and relative to chemical fungicid

254 With Placebo and Ustekinumab in Moderate to Severe Plaque Psoriasis in Subjects]) participated in a

255 d Retreatment With Brodalumab in Moderate to Severe Plaque Psoriasis Subjects], -2 [P3 Study Brodalum

256 Study Brodalumab in Treatment of Moderate to Severe Plaque Psoriasis], and -3 [Efficacy and Safety of

257 lnesses that vary from asymptomatic cases to severe pneumonia and death.

258 mitigate the cytokine storm associated with severe pneumonia caused by coronaviruses.

259 ociation between maternal place of birth and severe pre-eclampsia in the PreCARE cohort of pregnant w

260 ternal place of birth and the development of severe pre-eclampsia.

261 However, only 77% of women with severe preeclampsia/eclampsia received magnesium sulphat

262 This severe presentation may result from the virus using a vi

263 er quality are two of the most prevalent and severe pressures faced by coral reefs.

264 ing outcomes of MMCR vs ELR in patients with severe ptosis, there was a statistically significant hig

265 ost of the study period included the recent, severe regional drought in the western United States (20

266 allograft biopsies from 51 ITx patients with severe rejection, alongside 37 stable controls, were ana

267 ts with ANCA-associated vasculitis (AAV) and severe renal involvement is not established.

268 bing aspergillosis in COVID-19 patients with severe respiratory distress are being reported, but comp

269 t the mean monthly rate of visits related to severe respiratory illness in June through August of 201

270 Patients with mutations in PRPH2 exhibit severe retinal degeneration characterized by vast inter-

271 s may contribute to reduced efficacy against severe rotavirus disease.

272 erred substantial protection against any and severe rotavirus gastroenteritis to age 1 year.

273 le there are known clinical risk factors for severe RSV infection, the majority of those hospitalized

274 ailure (HF) patients with moderate-severe or severe secondary mitral regurgitation with transcatheter

275 of emergency department-attending sepsis and severe sepsis in adults was 1772 per 100 000 person-year

276 Due to its untargeted nature and the severe side effects it can cause, numerous nanomedicine

277 year study period, the overall prevalence of severe skin photoaging increased from 42% at baseline to

278 Genetic analyses of patients with severe spine segmentation defects have implicated severa

279 other COFs examined, likely due to the more severe steric impact of the dodecyloxy functionality on

280 Th2 inflammation and AHR in a mouse model of severe steroid resistant asthma, potentially through the

281 with acute mental stress may indicate a more severe stress reaction.

282 non-help-seeking samples based only on more severe symptom cutoff thresholds will likely have little

283 onsidering participants who had moderate and severe symptoms (23 to 100 points in OSDI), office worke

284 t cells (MCs) in various tissues, leading to severe symptoms and organ damage (eg, cytopenias, liver

285 eant to be used in patients with moderate to severe symptoms of COVID-19.

286 ld, newborns of infected mothers can display severe symptoms, including neurodevelopmental abnormalit

287 es (AAVs) are a group of disorders involving severe, systemic, small-vessel vasculitis and are charac

288 diagnosed DM had higher BMI and HbA1c, less severe TB, and more frequent comorbidities, DM complicat

289 1554 patients with mild-to-severe TBI were assessed at 6 months post injury on the

290 cells in naturally aged mice without causing severe thrombocytopenia.

291 cy; however, their use can be accompanied by severe toxicity.

292 lled 542 patients with TOF or PS and mild to severe TR who underwent isolated PVR (66.8%) or PVR+TVI

293 Severe trauma is the first cause of disability-adjusted

294 ns about optimal drug therapy in moderate to severe UC are complex, with limited guidance on comparat

295 f outpatients or inpatients with moderate to severe UC often requires the use of immunomodulator and/

296 itis-ichthyosis-deafness (KID) syndrome is a severe, untreatable condition characterized by ocular, a

297 No severe vaccine-related adverse events were reported.

298 suggesting one potential mechanism for more severe viral infection.

299 erited retinal disease (IRD) associated with severe visual loss, nystagmus, amaurotic pupils, oculo-d

300 ppressed intact PTH only among patients with severe vitamin D deficiency.