ライフサイエンスコーパス: severe depression

1 0 to 52, with higher scores indicating more severe depression).

2 0 to 60, with higher scores indicating more severe depression).

3 0 to 60, with higher scores indicating more severe depression).

4 score, 0 to 60; higher scores indicate more severe depression).

5 ates no to minimal depression; >20 indicates severe depression).

6 no evidence of shifts in symptoms of mild or severe depression.

7 ld depression, and gender is associated with severe depression.

8 rized as no depression, mild depression, and severe depression.

9 iciency is associated with a twofold risk of severe depression.

10 H2-R441H) was identified in individuals with severe depression.

11 and deflate heritability estimates for less severe depression.

12 lable are needed for people with moderate or severe depression.

13 sion over time, rather than necessarily more severe depression.

14 least mild depression, and 18 % moderate to severe depression.

15 broadly distributed across participants with severe depression.

16 euroimmunologic activation, particularly for severe depression.

17 34, moderate depression; and 34 and higher, severe depression.

18 opulation of patients with schizophrenia and severe depression.

19 mobility in patients with schizophrenia and severe depression.

20 al cortical regions in 3 human subjects with severe depression.

21 h other neuropsychiatric symptoms, including severe depression.

22 end toward higher risks for exposure to more severe depression.

23 is one of the most effective treatments for severe depression.

24 ECT is the most effective treatment for severe depression.

25 is a robust and rapidly acting treatment for severe depression.

26 ere gastroesophageal reflex, and moderate to severe depression.

27 it was 60.3; 27% of patients had moderate to severe depression.

28 ajor depression is overstated and limited to severe depression.

29 tidepressants show little benefit except for severe depression.

30 ssociations may reflect drug effects or more severe depression.

31 herapy (ECT) is the most potent treatment in severe depression.

32 ative to pill placebo for patients with less severe depression.

33 ia; anxious or melancholic features; or more severe depression.

34 selected to represent those with moderate to severe depression.

35 nt was predicted by integrated care and more severe depression.

36 low-up, and drug treatment for patients with severe depression.

37 dicts early recovery among persons with less severe depression.

38 people with self-defined anxiety attacks and severe depression.

39 children with multifocal retinoblastoma with severe depression (1.4% vs 10.2%, P < .02), and no diffe

40 tion (2.8 [0.17] vs 2.2 [0.13]; P =.008) and severe depression (1.9 [0.15] vs 0.9 [0.09]; P<.001), re

41 Questionnaire-9 (cutoff scores for moderate/severe depression, 15), number of close friends, physica

42 ere more likely than men to have moderate to severe depression (18.0% vs 9.0%; 95% CI for difference,

43 r perception of what is possible in treating severe depression; 2) spurred a wave of basic, translati

44 73+/-13 years; 58% men), 15% had moderate to severe depression, 26% mild, and 59% none to minimal dep

45 line, 59 individuals (56.7%) had moderate to severe depression, 52 individuals (50.0%) had moderate t

46 tacks" in the past 12 months; 7.2% reported "severe depression." A total of 56.7% of those with anxie

47 and psychological problems (eg, moderate to severe depression according to the Patient Health Questi

48 drug use (aPR, 0.45 [95% CI, .20-.99]), and severe depression, alcohol dependence, and recreational

49 of those seen by a conventional provider for severe depression also used complementary and alternativ

50 hundred seven young people with moderate to severe depression and 94 healthy control participants co

51 ed 3 clinical subtypes: (1) individuals with severe depression and a large social network; (2) older,

52 re dichotomized into measures of moderate or severe depression and anxiety (ie, scores >=10), respect

53 s, with 29.1% and 27.2% experiencing mild-to-severe depression and anxiety, respectively.

54 ioral and volitional changes which accompany severe depression and its treatment.

55 f a synergistic negative association between severe depression and recreational drug use (aPR, 0.37 [

56 this study eventually recovered, those with severe depression and self-perceived parent-child confli

57 alent mental health condition and results in severe depression and suicide attempts in the social com

58 esting that this may be a surrogate for more severe depression and that severity of depression is ass

59 to MDD patients ranging between moderate to severe depression and the effects of medication could no

60 ne QIDS-SR16 score of more than 20 (ie, very severe depression) and starting treatment as inpatients

61 nge: 0-52, with the highest score indicating severe depression) and time to remission (defined as HDR

62 nnaire) testing revealed 42% had moderate to severe depression, and 38% had moderate to severe anxiet

63 Rates of suicide ideation, severe depression, and acute psychosis have surged, para

64 iated with increased risk for schizophrenia, severe depression, and other nonaffective psychoses, but

65 ciated with increased risk of schizophrenia, severe depression, and other nonaffective psychoses.

66 al problems including cardiovascular injury, severe depression, and psychosis.

67 with a long illness duration and moderate to severe depression appear to benefit from antidepressants

68 d lower rates of probable mild, moderate, or severe depression as calculated by Patient Health Questi

69 dependent cohort of subjects with clinically severe depression (as measured by Hamilton Depression Sc

70 ction, showed that patients with moderate to severe depression at baseline (adjusted hazard ratio [HR

71 Patients had chronic moderate to severe depression at baseline (the mean MADRS score was

72 ore of 10 or greater (indicating moderate to severe depression) at 1 or more time points during the f

73 es (range, 0-27; higher score indicates more severe depression) at 3 months.

74 However, patients with severe depression (baseline Hamilton depression scale sc

75 verall, parents displayed mild, moderate, or severe depression (BDI) (n = 37, 26.7%); mild, moderate,

76 ith increased inflammatory proteins and more severe depression but differed in terms of myeloid and l

77 oms for patients with persistent moderate to severe depression, but functional outcomes and economic

78 ain stimulation is a promising treatment for severe depression, but lack of efficacy in randomized tr

79 ropean countries to treat mild to moderately severe depression, but the mechanism of antidepressant a

80 Here we review the genetics of severe depression by using clinical markers of severity

81 n (CES-D 16-26) and 97 (12%) for moderate to severe depression (CES-D > or =27).

82 Students with moderate to severe depression, compared with no to minimal depressio

83 antidepressant medications treat moderate to severe depression effectively, but there is less data on

84 ty-four male patients with schizophrenia and severe depression from an inpatient psychiatric centre p

85 re 9 (PHQ-9) indicating moderately severe to severe depression from ten primary health centres in Goa

86 re (range, 0-60; higher scores indicate more severe depression) from baseline to day 43.

87 On average 11.5% (21/182) scored severe depression (>= 10) on PHQ-9 and 85.2% (115/182) s

88 he depressed subjects, especially those with severe depression, had a significantly higher serum meth

89 Preoperatively, severe depression (HADS score >/= 11) was seen in 20% of

90 cluding schizophrenia, bipolar disorder, and severe depression have earlier onset of cardiovascular r

91 Less severe depression, having received adequate antidepressa

92 Elderly individuals with severe depression, history of suicide attempts with seri

93 Health Questionnaire-9 detected moderate to severe depression in 17% of the patients with pHPT and 7

94 tage 0 were the presence of schizophrenia or severe depression in a first-degree relative.

95 eceptor signaling respond to dopamine with a severe depression in action potential firing rate, while

96 base supporting the efficacy of ECT to treat severe depression in elderly patients.

97 lation (aiTBS), in patients with moderate to severe depression in need of ECT.

98 reduce depressive symptoms and prevent more severe depression in older people.

99 ellors to patients with moderately severe to severe depression in primary health-care settings.

100 e was for patients with moderately severe to severe depression in routine primary care in Goa, India.

101 e was for patients with moderately severe to severe depression in routine primary care in Goa, India.

102 nexplained behaviors, cognitive decline, and severe depression in the trained fighters ensued.

103 intervention in the treatment of moderate to severe depression in young males (18-25 y).

104 Factors positively associated with mild-to-severe depression included being female (Prevalence rati

105 troconvulsive therapy (ECT) is indicated for severe depression, including depression with psychosis,

106 However, severe depression is more often found in those whose chi

107 connectivity could predispose individuals to severe depression, it could also be leveraged to bring a

108 ncer, one of pancreatitis/sepsis, and one of severe depression leading to noncompliance.

109 However, HTE was higher in more severe depression levels (beta = 0.04; 95% CrI, 0.01 to

110 ls pretreated with antidepressants have less severe depression-like symptoms after the administration

111 vior was closely associated with moderate to severe depression, male gender, and greater impairment i

112 ost commonly reported events were psychosis, severe depression, mania or agitation, hallucinations, s

113 tance abuse, and less history at baseline of severe depression, manic symptoms, suicidality, subsyndr

114 ly recruit patients with at least moderately severe depression may be more informative and efficient

115 urban high-risk neighborhoods reported more severe depression (mean estimate [SE], 1.97 [0.79]; P =

116 rformance was observed between more and less severe depression, men and women, and primary versus spe

117 symptomatology (p = .034), and patients with severe depression (n = 29) had 43% higher CSF WCC relati

118 1, treatment-seeking adults with moderate-to-severe depression (N = 40) completed the task at baselin

119 Severe depression necessitated the discontinuation of in

120 ormance (odds ratio=1.60, 95% CI=1.02-2.49), severe depression (odds ratio=2.62, 95% CI=1.34-5.10), a

121 The severe depression of cardiac function responded promptly

122 alpha reactivation concomitantly resulted in severe depression of cardiac power and efficiency in the

123 and elevated SA, which appear to result from severe depression of catalase levels, may be responsible

124 single HisRS gene in T. brucei is shown by a severe depression of parasite growth rate that results f

125 -65 years screened with moderately severe to severe depression on the Patient Health Questionnaire 9

126 sh, Mandarin, or Cantonese, with moderate to severe depression or anxiety symptoms assessed using the

127 surrogate decision-making and either mild-to-severe depression or anxiety.

128 ental disorders, identified as self-reported severe depression or other psychological distress, were

129 However, few studies included women with severe depression or suicidal ideation.

130 CI, 1.81-11.70; P = .008), a higher risk of severe depression (OR, 4.37; 95% CI, 1.64-11.63; P = .02

131 ported by volunteers without severe anxiety, severe depression, or cognitive problems.

132 d October 31, 2018, for moderate depression, severe depression, or severe depression with psychosis w

133 Individuals with pain reported more severe depression (p's = 0.008-0.022) and anxiety (p = 0

134 ication of AA, risk of suicidal ideation, or severe depression (PHQ-9 score >20).

135 ICD-positive patients had more severe depression, poorer sleep quality and reduced qual

136 was negatively associated with both mild-to-severe depression (PR = 0.97, 95%CI: 0.95, 0.99) and anx

137 s who were assigned to intervention had less severe depression (range, 0 to 4 on a checklist of 20 de

138 For patients with moderate to severe depression receiving care from non-physician prim

139 ticipants 60 years or older with moderate to severe depression recruited at 7 psychiatric-psychothera

140 prescription pattern to reduce the risk of a severe depression-related outcome (SDO) when choosing be

141 with anxiety attacks and 53.6% of those with severe depression reported using complementary and alter

142 of premorbid IQ score and risk of developing severe depression requiring hospital admission.

143 vovirus infection, aspiration pneumonia, and severe depression, respectively.

144 6 and > or =27 represented mild and moderate/severe depression, respectively.

145 s, and 29.1% of the subjects had moderate to severe depression (score > or =21).

146 erate depression (score 10-14) or moderately severe depression (score 15-19).

147 or older, not pregnant, and had moderate to severe depression (scoring >=11 on the nine-item patient

148 disorders (schizophrenia, bipolar disorder, severe depression, severe anxiety, and severe post-traum

149 Pooling of studies examining severe depression showed a 5% decrease in risk of severe

150 phic sleep profile) and more severe and less severe depression subgroups (on the basis of pretreatmen

151 alence of symptoms of social dysfunction and severe depression suggest the need for implementation of

152 onpsychotic TRD who had moderately severe or severe depression, suggesting that these patients may co

153 RR, 0.30; 95% CI, 0.25-0.36) and moderate to severe depression symptoms (aRR, 0.75; 95% CI, 0.65-0.86

154 s with elevated IL-6 and IL-10 reported more severe depression symptoms at the post-HCT assessments.

155 duals presented a higher risk of moderate to severe depression symptoms compared with US-born individ

156 ion and Tenth Revision codes and moderate to severe depression symptoms defined by self-reported Pati

157 lly elevated inflammation, and reported more severe depression symptoms than heterosexuals.

158 acial and ethnic groups, PDD and moderate to severe depression symptoms varied by maternal nativity i

159 reactive protein and interleukin-6; and more severe depression than the uninflamed majority of cases.

160 I 1.4-4.0]; p=0.001) and mild or moderate to severe depression that persisted from baseline to 6 mont

161 of HD-tDCS in participants with moderate to severe depression, the 12-day HD-tDCS therapy was observ

162 For patients with very severe depression, the benefit of medications over place

163 CT) induces neuroplasticity in patients with severe depression, though how this relates to antidepres

164 ition-related hallucinations, or moderate to severe depression to suggest a prodrome of an alpha-synu

165 Severe depression, trait anxiety, and poor visuospatial

166 In adolescents with moderate to severe depression, treatment with fluoxetine alone or in

167 y 54.9% of all participants with moderate to severe depression used antidepressants, suggesting under

168 with anxiety attacks and 19.3% of those with severe depression visited a complementary or alternative

169 Prevalence of moderate to severe depression was 14.3% (95% confidence interval [CI

170 After adjustment, moderate to severe depression was associated with nearly a 2-fold in

171 In the main analysis, severe/moderately severe depression was associated with the incidence of 2

172 Moderate/severe depression was associated with time to first shoc

173 .1% of the participants, whereas moderate to severe depression was found in 12.7%.

174 Moderate to severe depression was infrequent at randomization (11.5%

175 Prevalences of mild and moderate to severe depression were 14.9% and 7.2%, respectively.

176 A total of 57 313 participants with severe depression were included in the analysis.

177 Subjects with marked or severe depression were more likely to respond to the scr

178 pressive symptoms, syndromal depression, and severe depression-were assessed over the 5 years before

179 ngside CBT, for adolescents with moderate to severe depression who are attending routine specialist C

180 eaningful clinical outcomes in patients with severe depression, who otherwise would have received ECT

181 e depression showed a 5% decrease in risk of severe depression with increasing (2-year increment) age

182 Current guidelines recommend treating severe depression with pharmacotherapy.

183 r moderate depression, severe depression, or severe depression with psychosis were included in the st