ライフサイエンスコーパス: severity

1 and determine their association with disease severity.

2 ough different treatment modalities based on severity.

3 st-FMT was indicative of ameliorated disease severity.

4 ylated regions (DMRs) associated with asthma severity.

5 es 1 and 3, similarly to disease control and severity.

6 ffer therapeutic approaches to alleviate SAH severity.

7 rotein could be used as markers for COVID-19 severity.

8 m arthritis patients correlated with disease severity.

9 st classifier for directly predicting asthma severity.

10 se 2019 (COVID-19) causes a range of illness severity.

11 somnolence and nearly all TEAEs were mild in severity.

12 pattern in blood, which changes with disease severity.

13 unogenicity, leading to an impact on disease severity.

14 pitation and increased drought frequency and severity.

15 re to prioritize patients based upon disease severity.

16 r networks independent of individual deficit severity.

17 atients correlates with fibrosis and disease severity.

18 can cause respiratory infections of varying severity.

19 sm, replication, immune evasion, and disease severity.

20 that are associated with features of asthma severity.

21 ng to the concomitant damage associated with severity.

22 gregates, a biomarker of HD pathogenesis and severity.

23 ed Tc17 cell subsets associated with disease severity.

24 ecific immune responses and COVID-19 disease severity.

25 y duration persisted, independent of obesity severity.

26 pe, genetic modifiers, and XCI to phenotypic severity.

27 ation and coagulopathy contribute to disease severity.

28 s and are proposed as a predictor of disease severity.

29 c health burden, which increases with asthma severity.

30 r adjusted odds ratios whatever the level of severity.

31 eventing infection and modulation of disease severity.

32 further development and could reduce symptom severity.

33 or myocardial infarction, including stenosis severity.

34 gnostic thresholds used to determine disease severity.

35 ability and provided information on mutation severity.

36 childhood trauma in predicting worse symptom severity.

37 n drug seeking is associated with dependence severity.

38 ers only the first event irrespective of its severity.

39 mmune pathways to profoundly advance disease severity.

40 scores were used as measures of pancreatitis severity.

41 uit's potential as a biomarker of dependence severity.

42 -19-infected patients in relation to disease severity.

43 cted gingival tissues, and increases disease severity.

44 are significantly correlated to the disease severity.

45 -reactive CD4(+) T cells in distinct disease severities.

46 al IgA) may be a correlate of susceptibility/severity; (2) RSV-specific CD8+ T cells in bronchoalveol

47 zed for PGE(2) levels and correlated against severity; 9alpha,11beta-PGF(2) and PGI(2) metabolites we

48 ectroscopy, for assessing endoscopic disease severity according to the four-level Mayo subscore.

49 that Bowel Disorders occur on a continuum of severity across multiple symptom areas.

50 Baseline stroke severity adjusted regression model showed that changes w

51 of treatment limitation and its influence on severity-adjusted ICU mortality rate.

52 ients; most (94.4%) were mild-to-moderate in severity and 98.8% were deemed unrelated to study treatm

53 and were associated with similar hypertrophy severity and adverse event rates as observed with trunca

54 inistration of activin-A ameliorates disease severity and alleviates CNS immunopathology and demyelin

55 d IL-17A and KLK-7 as biomarkers for disease severity and apremilast pharmacodynamic effect in psoria

56 were positive correlations between clinical severity and both subcortical tau pathology (R = 0.667,

57 rial profile was associated with IBS symptom severity and breath tests results at baseline (H(2) and/

58 AD and significantly correlated with disease severity and complement activation.

59 tures contribute toward variation in disease severity and confound genotype-to-phenotype analyses.

60 ,595 children with data on asthma (including severity and control) in Grades 7-8 and 9, school perfor

61 igatus, in the airway correlated with asthma severity and control.

62 lable disease-modifying therapies can lessen severity and delay progression.

63 y.IMPORTANCE While HSV antivirals reduce the severity and duration of clinical disease in some indivi

64 ial diversity increased in parallel with the severity and extent of periodontitis.

65 d oncostatin M-which correlated with disease severity and increased bacterial products in plasma.

66 The degree of insomnia correlates with PD severity and it responds to treatments that decrease pat

67 s show an association with increased disease severity and may help stratify patients and selection of

68 Obesity influences asthma severity and may impair response to beta-AR agonists.

69 fically for COVID-19 to help predict disease severity and mortality.

70 nsider their impact both on COVID-19 disease severity and on viral spread in a population.

71 th cardiogenic shock and may aggravate shock severity and organ failure.

72 echanisms by which T cells influence disease severity and outcome are not well understood.

73 d with increasing nonperfusion, worsening DR severity and presence of PPL.

74 m of this study was to establish the disease severity and prognostic factors for disease outcome by a

75 After adjusting for disease severity and relevant clinical factors, even small amoun

76 pplication of GDF-15 as biomarker of disease severity and response to deoxynucleoside treatment in pa

77 ated adverse events were mild or moderate in severity and similar across treatment groups.

78 se these sequelae for accurate assessment of severity and treatment planning, if indicated.

79 hic changes, and the relationship to disease severity and viral clearance in COVID-19 patients.

80 n the values of HRCT scores for both disease severity and viral clearance, a standardised HRCT score

81 (8.78 +/- 3.9; greater scores reflect worse severity) and differed among 5 phenotypic groups.

82 and associated with GSDMB expression, asthma severity, and asthma exacerbations (P < .05).

83 used to determine differences across disease severity, and correlations were determined by using Spea

84 Over the past decade, incidence, severity, and costs associated with C. difficile infecti

85 ing the association between DM and knee pain severity, and to explore the association between DM and

86 tronger when further adjusting for admission severity (aOR 1.85 95% CI 1.06-3.24).

87 sal mask and pneumotachograph to measure OSA severity, arousal threshold and upper airway muscle resp

88 thy ageing; their role as markers of disease severity assessing the correlation with clinical variabl

89 Second, CHIT1 reflected disease severity at a median 5 years later (p = 1.2E-04).

90 ONSD values were correlated with disease severity, baseline brain magnetic resonance imaging or c

91 ponse to coronavirus disease 2019 (COVID-19) severity, beneficial antiviral immune responses may be i

92 onset of cGVHD was not associated with cGVHD severity but was a significant independent risk factor f

93 t have higher COVID-19 mortality or clinical severity, but 614G is associated with higher viral load

94 sitivity by EIA and CCA associated with IDSA severity, but not with subsequent adverse outcomes.

95 e that hyperglycaemia may increase influenza severity by damaging the pulmonary epithelial-endothelia

96 8 hr) and was correlated with encephalopathy severity by Glasgow Coma Scale in critically ill patient

97 ring stress and were related to malformation severity.(C) RSNA, 2020: An earlier incorrect version of

98 a-virus-associated respiratory infections by severity, case ascertainment, region, and age.

99 more frequently in high-severity versus low-severity cases (0.98 vs 0.40 events/case, P < 0.001).

100 espectively, and mean vector slopes for each severity categories were 0.79, 0.95, 1.95, and 2.08, res

101 nzyme-linked immunosorbent assay) and dengue severity, categorized using 3 definitions.

102 In addition, we defined a new severity category (level IV) with prolonged exposure to

103 evaluate risk factors associated with damage severity caused by Hurricanes Maria and Irma across Puer

104 ted a quantitative scale of clinical disease severity comprising of four major disease domains (seizu

105 lness has been reported, but whether illness severity correlates with infectivity is unknown.

106 distributed over a broad range, with symptom severity correlating directly with virus-specific antibo

107 a did not identify a strain genotype-disease severity correlation.

108 nfirmed COVID-19 and at least one additional severity criteria as follows: use of oxygen supplementat

109 for potential confounders including glaucoma severity, CS, age, and visual acuity (P = .004 better ey

110 ould be considered when updating current BPD severity definitions.

111 exhibited a strong correlation with delirium severity (DeltaR2 = 0.208, P < 0.001).

112 re significantly associated with baseline DR severity, disease progression, and treatment requirement

113 xpression correlated positively with disease severity (eosinophils/high-power field) and BZH.

114 has been shown to improve depression symptom severity, fatigue, and sexual function in small studies

115 We show that low-severity fires can increase the pool of stable soil carb

116 Levels of periodontitis severity followed two criteria: (1) Center for Disease P

117 Model to compare outcomes by age and illness severity for the United Network for Organ Sharing-approv

118 Diverticular disease can range in severity from symptomatic uncomplicated diverticular dis

119 Demographic data, TBM severity grade, HIV co-infection status, and clinical en

120 y after TAI was 7.8%, and depended on injury severity (grade IV (free rupture) 20.9%).

121 lementation of guidelines for the diagnosis, severity grading, and treatment of sinusoidal obstructiv

122 re experiencing at least one GI symptom of a severity greater than normative levels.

123 PCI values in comparison to the other two MS severity groups (severe: p = 0.001, moderate: p = 0.02).

124 (129)Xe MRI correlates with asthma severity, health care utilization, and oral corticostero

125 nancy was associated with increased COVID-19 severity (HR, 1.90; 95% CI, 1.30 to 2.80).

126 olorspace can be used to estimate burn depth severity immediately after burning.

127 significantly associates with kidney disease severity in a patient cohort with CEP290 mutations.

128 ple assay, proved a valuable early marker of severity in ABP with clear advantages for prediction of

129 biomarkers of RSV susceptibility or disease severity in adults were: (1) lower anti-RSV neutralizing

130 of COVID-19 patients with different clinical severity in comparison with healthy individuals.

131 enotype ON1 genetic variability and clinical severity in infants hospitalized with bronchiolitis over

132 annot determine whether different degrees of severity in morbidity or mortality failed to be statisti

133 the main microbiota associated with fibrosis severity in non-obese subjects.

134 eus (STN) beta activity is linked to symptom severity in Parkinson's disease (PD), but few studies ha

135 etic and epigenetic architecture of reaction severity in peanut allergy.

136 ic space, we quantified rust (Puccinia spp.) severity in switchgrass (Panicum virgatum) plantings at

137 sponses occurred at the time of peak disease severity in the ceca and colons of all mice infected wit

138 Effects of ASD and its severity included reduced levels of multiple metabolites

139 development between individuals whose autism severity increased, remained stable, or decreased sugges

140 rea and the change in the Psoriasis Area and Severity Index (PASI) score (range, 0 to 72, with higher

141 etwork with a self-calibrated Palmer Drought Severity Index (scPDSI) dataset to derive the South Amer

142 ients with severe AD (median Eczema Area and Severity Index = 28.3; interquartile range = 25.2-35.3).

143 as percentage improvement in Eczema Area and Severity Index from baseline at week 16.

144 patients achieving EASI-50 (Eczema Area and Severity Index) or EASI-75, as well as patient-reported

145 statistically significantly: Eczema Area and Severity Index, SCOring AD, Patient-Oriented Eczema Meas

146 Visual field (VF) loss severity is associated with higher driving simulator cra

147 ronic obstructive pulmonary disease risk and severity is controversial.Objectives: To comprehensively

148 ircuit relationship with nicotine dependence severity is dysregulated following chronic nicotine admi

149 Because delineation of clinical severity is often difficult in children, (129)Xe MRI may

150 Subset analyses examined HIV and HCV disease severity markers separately and jointly.

151 tients with prior stroke had a higher stroke severity (median National Institutes of Health Stroke Sc

152 eriolar diameter increased with worsening DR severity (mild NPDR: 10% vs PDR: 31%, P = 0.007).

153 Severity models demonstrated excellent discrimination (o

154 g for gestational age, birth weight, and BPD severity, MR-EI was associated with LOS and duration of

155 per hour) to define obstructive sleep apnea severity (normal, <5.0; mild, 5.0-14.9; moderate, 15.0-2

156 athway and to the enhanced sinonasal disease severity observed in AERD.

157 SARS-CoV-2 infection (n = 115) with various severities of COVID-19 were tested for SARS-CoV-2-specif

158 only found at anatomic interfaces across all severities of traumatic brain injury, we combined comput

159 orsinB expression levels impact the onset or severity of abnormal movements or neuropathological feat

160 The age and illness severity of adult ICU trauma patients in Australia and N

161 The occurrence and severity of AL, but not overall complications, after MIE

162 significant differences in the frequency or severity of any of the 12 individual symptoms assessed.

163 Routine biomarkers could predict severity of appendicitis with high specificities, but lo

164 eatment assessment to evaluate change in the severity of bothersome tics.

165 C-peptide and stratifies subjects for future severity of C-peptide loss after 1 year.

166 mMUD remained poor, possibly related to the severity of chronic GvHD.

167 s should predict variability in the type and severity of cognitive deficits after traumatic brain inj

168 nvestigated the effects of wheat and ATIs on severity of colitis and fecal microbiota in mice.

169 gy distribution within cells and reduces the severity of colitis in mice.

170 tines of mice on control diets increased the severity of colitis in these mice.

171 Mediterranean diet reduces the incidence and severity of coronary artery disease, whereas supplementa

172 icing cardiologists to accurately assess the severity of coronary stenosis without resorting to invas

173 Increased severity of cortical superficial siderosis was associate

174 demiological analyses which observed reduced severity of COVID-19 in countries with universal BCG vac

175 The severity of COVID-19 lung disease is higher in the elder

176 r insight into potential causes of increased severity of COVID-19 symptoms in certain individuals.

177 o ramipril had no impact on the incidence or severity of COVID-19.

178 To determine the severity of damage within these connections, (i) fractio

179 used for detecting depression and assessing severity of depression.

180 essed using the Tinnitus Questionnaire (TQ), severity of depressive mood states examined using the Be

181 onship of SARS-CoV-2 pulmonary infection and severity of disease is not fully understood.

182 ole in supporting the diagnosis, grading the severity of disease, guiding treatment, detecting compli

183 es in retinal layer structuring based on the severity of DR.

184 The prevalence as well as the severity of dry eye disease increase with age.

185 or elevation maps of corneas with a range of severity of FECD were evaluated in a randomized manner f

186 ses may have consequences for the timing and severity of future outbreaks.

187 study were to describe early occurrence and severity of gaseous embolism (GE) and DCS in marine turt

188 Prevalence and severity of gingival recession was higher at the sites w

189 Age, type and severity of glaucoma, PTM, or total energy delivery had

190 severity, total SLT power, type of glaucoma, severity of glaucoma, visual field mean defect, and reti

191 Increasing severity of hyponatremia was associated with encephalopa

192 body mass index, higher d-dimer, and greater severity of hypoxemia on ICU admission.

193 ssociated with both systemic and respiratory severity of illness and is also associated with use of l

194 When a treatment dose is associated with severity of illness and should be dosed "enough," logist

195 ility weighting to adjust for confounding by severity of illness lead to biased results.

196 s and granular measures of comorbidities and severity of illness.

197 actors involved in clinical presentation and severity of IMD-W cc11.

198 ve compared the clinical characteristics and severity of infection among the individual PIV serotypes

199 y bowel disease, modulating the location and severity of inflammation and fibrosis.

200 usly shown to associate with lung damage and severity of influenza virus infection.

201 t due to its rapidly changing nature and the severity of its associated outcomes.

202 The observed rates of hypoglycemia with severity of level 2 (blood glucose level, <54 mg per dec

203 endothelial dysfunction) were related to the severity of liver cirrhosis (CTP score), mainly IP-10 an

204 ery prevented HSC activation and reduced the severity of liver fibrosis compared with mice given vehi

205 pe mice with an anti-CCL2 mAb attenuated the severity of liver injury.

206 The primary outcome was the severity of lung disease on admission chest radiographs,

207 Severity of macular thickening (i.e., CST) was associate

208 The clinical severity of malaria infections related strongly to the t

209 cytes, respectively, which was linked to the severity of monocyte subset alterations.

210 s will delay (in parallel) the appearance or severity of multiple chronic, non-communicable diseases,

211 patterns were measured by wrist actigraphy, severity of neurologic and systemic illness by Glasgow C

212 clinical penetrance (70%) and age-dependent severity of NFKB1-related phenotypes were observed.

213 cohol consumption is associated with reduced severity of nonalcoholic fatty liver disease (NAFLD), ba

214 ation activity score, reflecting the sum and severity of organ involvement and infections, days of ho

215 Baseline characteristics, including severity of pain and level of disability, were similar i

216 pancreatic activity of trypsin increases the severity of pancreatitis, even though loss of trypsin ac

217 in FSHD muscle biopsies correlates with the severity of pathology.

218 Mechanisms underlying the variable severity of peanut-allergic reactions remain unclear.

219 Conclusion There was a higher incidence and severity of physical intimate partner violence (IPV) dur

220 endent aldosterone production, where greater severity of production was associated with higher blood

221 g-term PGDHi was well-tolerated, reduced the severity of pulmonary fibrotic lesions and extracellular

222 moking (CS) can exacerbate the incidence and severity of RA.

223 s demonstrate that the scale, magnitude, and severity of recent thermal events are entraining the bio

224 re to NO(2) was associated with an increased severity of rhinitis, with similar adjusted odds ratios

225 Factors determining susceptibility to and severity of RSV disease in adults have not been well def

226 Phenotypes were scored for severity of skin condition, specific hair shaft defects,

227 Severity of SMA disease correlates inversely with SMN le

228 ive evaluation is to assess the presence and severity of small-vessel arteriopathy.

229 We find that the severity of splicing dysregulation correlates with disea

230 may help explain the increased frequency and severity of SSc among the AA population.

231 b2 was associated with a lower incidence and severity of systemic reactions than BNT162b1, particular

232 trains was hypothesized to contribute to the severity of the 2017-2018 season in North America.

233 d -C genes) may affect susceptibility to and severity of the disease caused by severe acute respirato

234 The severity of the disease is usually measured by the tumor

235 se showed a significant correlation with the severity of the disease.

236 t is variable and most likely related to the severity of the lung injury.

237 The presence and severity of various characteristics of drusen and other

238 g where feasible could improve assessment of severity of viral disease in the population.

239 s occur, or whether the relationship between severity of visual loss and changes in auditory abilitie

240 Recent increases in the prevalence and severity of wildfires in some regions have resulted in a

241 Background Disease severity on chest radiographs has been associated with h

242 Disease incidence and severity on fruit were analyzed based on citrus season,

243 gorously evaluating effects of diagnosis and severity on metabolites, as moderated by age, sex, and I

244 the study was to assess the impact of IBS-D severity on patient burden and patient and healthcare pr

245 hat they reflect behaviors only differing in severity on the same continuum of genetic liability coul

246 hese global network measures and IBS symptom severity or GI-specific anxiety but we found a significa

247 on factors such as stage of illness, symptom severity, or genetic liability.

248 mediated by viral load for each of 3 dengue severity outcomes.

249 d cpRNFL thickness measurement at any of the severities (P > 0.05).

250 found between lowland shrub cover with fire severity (r = 0.01).

251 orrelated significantly with graft rejection severity (r = 0.972, r = 0.729, and r = 0.823, respectiv

252 ose without (controls) with regard to stroke severity, rates of IVT/mechanical thrombectomy, symptoma

253 ) were used to measure delirium and delirium severity, respectively.

254 nation of FTND and NCC in discerning disease severity (ROC curve analysis: AUC = 0.746, P = 0.027) wa

255 sure of tic severity was the Yale Global Tic Severity Scale administered by an independent evaluator

256 e World Health Organization COVID-19 disease severity scale.

257 ver 30 months, major trauma patients [Injury Severity Score (ISS) >=9] admitted to 3 Level-I trauma c

258 lure) and COVID-19 cardiorespiratory ordinal severity score (worst to best: death, cardiac arrest, me

259 atients were severely injured (median injury severity score 33); 33% developed sepsis, 6% septic shoc

260 We propose a novel severity score specifically for COVID-19 to help predict

261 A threshold-weighted reaction severity score was calculated for each subject based on

262 mptomatic at baseline with a greater symptom severity score, but this was not found at >=6 months.

263 ntrolling for pre-training behaviors, Injury Severity Score, postgraduate training year, and days sin

264 , mechanism and intent of injury, and Injury Severity Score.

265 ounger than 60 years had significantly lower severity scores (CT-scores) (7.5 +/- 6.8).

266 essfully predicted the daily evolution of AD severity scores at an individual level and could inform

267 in corrected distance visual acuity (CDVA), severity scores of various ocular surface parameters, an

268 (95% CI 5.22 to 9.68) higher vision symptom severity scores throughout recovery versus those without

269 as assessed by change in the ocular surface severity scores was the primary outcome measure, while c

270 nalyses considering repeated events or event severity showed that ticagrelor monotherapy consistently

271 s have different time courses in the disease severity spectrum.

272 nd uninfected individuals as well as between severity stages.

273 m the ZETA trial were divided into 4 disease severity subgroups: progression and symptoms, symptoms o

274 The BAT was the best biomarker for severity, surpassed only by the SPT in predicting thresh

275 Medicated Archetypal MPDs had lower symptom severity than their unmedicated counterparts; whereas me

276 s to validate a new predictive model for BPD severity that incorporates respiratory assessments beyon

277 n conclusion, a new predictive model for BPD severity that incorporates respiratory assessments beyon

278 Age, glaucoma severity, total SLT power, type of glaucoma, severity of

279 Each complication was recorded regarding severity, type (cardiac, infectious, etc), etiology (sur

280 dity, previous symptom duration, and symptom severity, using a Bayesian piece-wise exponential primar

281 tive events occurred more frequently in high-severity versus low-severity cases (0.98 vs 0.40 events/

282 1st quartile-3rd quartile) score of rhinitis severity was 4 (2-6).

283 Symptom severity was assessed using the PANSS scale.

284 Additionally, increased disease severity was associated with globally slower flow speeds

285 Disease severity was correlated with results from viral culture,

286 Illness severity was lower than in non-HCWs.

287 ct of preinfection antibody titer on disease severity was mediated by viral load for each of 3 dengue

288 The primary outcome measure of tic severity was the Yale Global Tic Severity Scale administ

289 Diarrheal frequency, duration, and severity were negatively associated with bacterial diver

290 No differences in disease severity were noted among children infected with RSV A a

291 type, circulating PACAP, and somatic anxiety severity were stronger among females than males.

292 t none of the traditional measures of injury severity were.

293 Confusion Assessment Method (CAM) and CAM-S (Severity) were used to measure delirium and delirium sev

294 ascular zone size was not associated with DR severity when single OCTA images (P = 0.98) were conside

295 with confirmed influenza illness of varying severity who presented within a week after symptom onset

296 h higher coronary atherosclerosis extent and severity with a 2-fold increase across tertiles (28.4%-5

297 Ophthalmic manifestations increased in severity with increasing age of the patients (r = -0.84;

298 129)Xe MRI may be an important biomarker for severity, with potential to identify children at higher

299 acture risk increased with increasing eczema severity, with the strongest associations in people with

300 n increased with greater grades of emphysema severity within the emphysema group.