ライフサイエンスコーパス: sex

1 al behaviors directed to members of the same sex.

2 velopment in visual cortex of mice of either sex.

3 ere combined to produce FFMI models for each sex.

4 eticin and puromycin to kill the non-rescued sex.

5 hnicity in the main analysis, and further by sex.

6 lt gerbils (Meriones unguiculatus) of either sex.

7 such factors, particularly in the context of sex.

8 isk factors, incidence of malaria, or FOI by sex.

9 lence of 3-16% depending on country, age and sex.

10 n its level of expression, which varies with sex.

11 s those without, after adjusting for age and sex.

12 hologic reconstructions obtained from either sex.

13 ally active women as those who have ever had sex.

14 atidia and in vivo from intact flies of both sexes.

15 nce in risk of 90-day mortality between both sexes.

16 ells in the cochlear nucleus of mice of both sexes.

17 a different pattern of HPV infection between sexes.

18 on carried opposite consequences for the two sexes.

19 l milieu of the colon which vary between the sexes.

20 d overall survival (OS) were similar between sexes.

21 ncreased several signaling molecules in both sexes.

22 ty-frailty relationship was similar for both sexes.

23 ing in 20 young healthy participants of both sexes.

24 ve recall (AR) in human participants of both sexes.

25 22 women aged 15-24 who reported ever having sex: 326 adolescents (15-19 years) and 696 young women (

26 ian age was 50 years, 31% were female (natal sex), 43% black or African American and 15% Asian, the m

27 ity volume at 3-month follow-up adjusted for sex, 5-year age group, and general practice.

28 PrEP efficacy for covered sex acts, as defined in the HPTN 067/ADAPT protocol, was

29 gression models were used to obtain age- and sex-adjusted estimates.

30 lowest quartile (<200 pg/mL) in the age- and sex-adjusted model.

31 es or haemoglobin less than age-adjusted and sex-adjusted values), clinical malaria (infection and sy

32 These groupings remained after sex adjustment.

33 for potential confounders at patient level (sex, age) and practice level (list size, locality, pre-i

34 these four models are: polygenic risk score, sex, age, and education.

35 Sex, age, and number of atrophic foci predicted future p

36 e hospital at the same time were matched for sex, age, and residence.

37 t risk factor for velum-CCC, controlling for sex, age, BMI, and TS grade.

38 q2 software, using covariates to correct for sex, age, library batches, and 1 surrogate variable comp

39 utable fractions (PAF) were adjusted by age, sex, all other risk factors and socioeconomic position (

40 dgerigar (Melopsittacus undulatus; of either sex), an avian animal model with complex hearing abiliti

41 The estimated rates were calculated by age, sex and according to the Socio-Demographic Index (SDI).

42 used to estimate adjusted mortality rates by sex and age.

43 electronic cigarettes, across mouse strains, sex and ages.

44 (ORs) accounting for individual matching on sex and birth year were used to estimate the risk of XFS

45 en relevant, we provide information based on sex and common classifications of race/ethnicity, socioe

46 differ by ethnicity, when adjusting for age, sex and comorbidities, black patients were at higher odd

47 guide clinicians and researchers to consider sex and gender in their approach to diagnosis, preventio

48 All outcome measures were corrected for age, sex and intracranial volume.

49 In addition, the effect of age, sex and laterality were evaluated.

50 Sarea/LVEDV ratio on the association between sex and LV reverse remodeling (LV end-systolic volume ch

51 ernal temporal structure to humans of either sex and male macaque monkeys.

52 Both sex and maternal BCG vaccination status influenced the e

53 ween common patient characteristics, such as sex and metabolic comorbidities, and mortality from COVI

54 e effect of primary tumour subtype, age, and sex and on severe acute respiratory syndrome coronavirus

55 FGF23 serum concentrations adjusted for age, sex and principal components of ancestry were analyzed.

56 the entire range of GAs while adjusting for sex and size for GA.

57 ortance of recognizing the interplay between sex and social factors and enhances our understating of

58 modeling (LV end-systolic volume change) and sex and the composite outcome of all-cause mortality, LV

59 s about lung function test, smoking history, sex and the levels of D-dimer among two groups.

60 Sex and the microbiome are critical factors that should

61 resent evidence that the interaction between sex and weight gain alters the progression of allergic a

62 lpha in GHRH neurons disrupts growth in both sexes and causes pubertal delay in females.

63 te local LCIC circuits in adult mice of both sexes and found that input patterns are highly dependent

64 did impair novel object recognition in both sexes and social preference in females.

65 Failure to include both sexes and to address age in mechanistic atherosclerosis

66 1:10), who were individually matched by age, sex, and area of residence.

67 Older age, male sex, and being black or African American (compared to be

68 aim to describe the temporal trends in age, sex, and clinical characteristics at HCM diagnosis over

69 tions and each matched to 3 controls on age, sex, and cohort recruitment date.

70 When controlling for ventilator use, sex, and comorbid conditions, FIB-4 >=2.67 was also asso

71 not undergo bariatric surgery based on age, sex, and comorbid conditions.

72 Age, sex, and education were associated with long-term outcom

73 starkly atypical moderating effects of age, sex, and IQ.

74 geal adenocarcinoma, such as older age, male sex, and obesity, should undergo endoscopy.

75 files of human kidneys as a function of age, sex, and race.

76 ual demographic characteristics such as age, sex, and race/ethnicity, as well as by social factors in

77 maintained when adjusting for patient's age, sex, and total intracranial brain volume.

78 s for patients with cancer, considering age, sex, and tumour subtype.

79 ids varies among individuals and between the sexes, and this has been correlated with gender-specific

80 This study identifies sex- and age-specific gene changes in the mTORC1-activat

81 We estimated sex- and smoking-specific incidence trends of pre-bronch

82 istory of early-life stress (ELS) and female sex are associated with increased risk for depression.

83 vestment and lower frequency of extramarital sex are associated with more severe jealous response.

84 reward the effort invested in incorporating sex as a biological variable.

85 ge gap between the aspiration of considering sex as biological variable and the execution of such stu

86 e common marmoset (Callithrix jacchus, mixed sexes) as a model.

87 nmet care needs among women may reduce these sex-based AMI disparities.

88 ts of various ages, while we did not observe sex-based differences.

89 er adjusting for other TB risk factors (age, sex, BCG-vaccination and stays >=3 months in Africa/Asia

90 beta at 3.0 T = 0 msec per year, P = .83) or sex (beta at 1.5 T = -1 msec, P = .88; beta at 3.0 T = 6

91 standing the mechanism(s) driving the innate sex bias in neutrophil bactericidal capacity could ident

92 However, the mechanism(s) driving this sex bias in neutrophil killing have not been reported.

93 contributions of CR3, C3, and ROS to innate sex bias in the neutrophil response to S. aureus Given t

94 ses, and potential functional corollaries of sex-biased brain anatomy in humans.

95 hese findings establish conserved aspects of sex-biased brain development in humans and mice, and she

96 We propose that to understand causes of sex-biased mortalities, more complex analyses are needed

97 performed, controlling for covariates (age, sex, body mass index), examining interaction effects, an

98 After we adjusted for age, sex, body mass index, and type-2 diabetes in the phase 2

99 emained significant after adjusting for age, sex, body mass index, type 2 diabetes, and country.

100 For healthy and unhealthy people of both sexes, both the 97.5th and 2.5th GFR percentiles exhibit

101 n cardiac function and flow, on the basis of sex, by quantifying cardiac flow characteristics and rel

102 antiviral chromatin silencing machinery for sex chromosome dosage compensation.

103 supergene does not follow standard models of sex chromosome evolution, in which distinct evolutionary

104 Neo-sex chromosomes are found in many taxa, but the forces d

105 The origin and early evolution of sex chromosomes have been hypothesized to involve the li

106 Sex chromosomes in cells have the potential to affect pr

107 ated with higher all-cause mortality in both sexes combined.

108 ission of psychotic symptoms and 19 age- and sex-comparable control subjects underwent simultaneous f

109 t rate changes with a delay which was highly sex dependent (95% adaptation in females and males after

110 ere, we tested the hypothesis that mood- and sex-dependent alterations in brain circuitry implicated

111 Sex-dependent differences in fetal weight, placenta hist

112 This could be attributed to sex-dependent differential expression of genes (DEGs) in

113 These regions were compared to understand if sex determination is controlled via the same physiologic

114 An understanding of the genetic basis of sex determination may lead to new methods of managing th

115 /NR1F1 functions downstream of the canonical sex-determination pathway.

116 sencephaly and individuals with disorders of sex development, and through international research coll

117 sistent benefits for subgroups based on age, sex, diabetes, treatment with an ARNI and baseline eGFR,

118 The data reveal a sex difference in the adaptation of the PSD scaffold to

119 work on the topic has focused on a proposed sex difference in the type of jealousy (sexual or emotio

120 No sex difference in time to task failure was observed in e

121 sorder in women may need to account for this sex difference.

122 This study analyzed sex differences among cornea specialists with regards to

123 Sex differences and social context independently contrib

124 with MI and compared these associations with sex differences in a control group without a history of

125 There are clinically relevant sex differences in acute and chronic pain mechanisms, bu

126 There are sex differences in arterial stiffness and neural control

127 Humans display reproducible sex differences in cognition and behavior, which may par

128 Student t test was used to evaluate sex differences in cRNFL thickness globally and at each

129 components of animals life that may include sex differences in exposure to predators, immune capacit

130 physiological mechanisms that contribute to sex differences in fat storage.

131 there is a need for better understanding of sex differences in immune function and opioid pharmacoki

132 their recent article, Takahashi et al. found sex differences in immune responses to SARS-CoV-2 and th

133 We propose that sex differences in immunopathogenesis will inform mechan

134 ults add to growing evidence indicating that sex differences in learned fear inhibition are associate

135 Our analyses suggest that the magnitude of sex differences in mammalian mortality patterns is likel

136 om-effects meta regression estimated whether sex differences in not enrolling ("screen out") varied b

137 This study assessed sex differences in recurrent MI, recurrent CHD events, a

138 behavior, which may partly reflect intrinsic sex differences in regional brain organization.

139 We investigated sex differences in subcutaneous adipose tissue transcrip

140 oductive hormones on cerebral blood flow and sex differences in the ability of the cerebral vasculatu

141 siological mechanism for previously observed sex differences in the comorbidity of major depression a

142 ens, our work illustrates the vast extent of sex differences in the molecular mechanisms underlying p

143 Sex differences in the neurovasculature response post-TB

144 VN in male and female rats and characterized sex differences in the RLN3 innervation of the PVN.

145 Further, sex differences in these comorbidities are substantial.

146 While sex differences in vulnerability have been identified wi

147 Biological sex differences may manifest themselves in susceptibilit

148 Moreover, the neural basis for the sex differences observed in the clinical arena is unknow

149 Sex differences were noted in control mice, in which fem

150 linked to robust psychological or behavioral sex differences.

151 proteins known to play an important role in sex differentiation.

152 e grapevine was the transition from separate sexes (dioecy) in wild Vitis vinifera ssp. sylvestris (V

153 Previously observed racial and sex disparities in living donor kidney transplantation d

154 contraindication may have reduced racial and sex disparities in metformin prescription in moderate ki

155 cause mortality after adjustment for age and sex, driven by early and noncardiovascular death.

156 of Held terminals of juvenile mice of either sex during high-frequency spiking.

157 immune activation appear to be small across sexes during long-term suppressive therapy.

158 Age, sex, dyslipidemia, hypertension, smoking, and family his

159 ng for depressive symptoms at baseline, age, sex, education, and income (PROSPERO CRD42018091627).

160 tantial DG-specific damage in mice of either sex either by diphtheria toxin-based ablation of >50% of

161 istory of tumors, after controlling for age, sex, enrollment period, and paternal origin (adjusted HR

162 expression in five dimensions: space, time, sex, environment, and subcellular localization.

163 Genomic sex estimates were 100% consistent with proteomic and os

164 stic quantile regression, adjusting for age, sex, ethnicity, education level, smoking, BMI, and diabe

165 Adult offspring of both sexes exposed to + Nic exhibited elevated locomotor acti

166 ), which were then crossed with mice of both sexes, expressing ALS-linked gene mutants for TAR DNA-bi

167 somes from Slc38a1 knock-down mice of either sex further support its role as a D-serine reuptake syst

168 on to female and male BALB/c mice (10 animal/sex/group) along with their human blood compatibility.

169 mance among diverse ethnic, racial, age, and sex groups for all new artificial intelligence tools to

170 g to streptococcal species adjusted for age, sex, >=3 positive blood culture bottles, native valve di

171 Male sex (hazard ratio [HR] 2.54, P = 0.02), diabetes (HR 2.3

172 Male sex (hazard ratio, 1.89 [95% CI, 1.04-3.44]; P=0.04) and

173 he multivariable analysis adjusting for age, sex, hepatitis B e antigen serostatus, and diabetes, the

174 The human ovary orchestrates sex hormone production and undergoes monthly structural

175 VAT are determined by the tissue niche in a sex-hormone-dependent manner to limit adipose tissue inf

176 vertebrate body change under the control of sex hormones.

177 d model showed that risk factors were female sex (HR 2.52, 95% CI 1.04-6.10), history of smoking (HR

178 Those associated with sICH were male sex (HR 2.68, 95% CI 1.06 to 6.83), history of hyperlipi

179 years (HR = 1.22, 95% CI 1.03-1.44), female sex (HR = 1.5; 95% CI 1.3-1.74), white ethnicity (HR = 1

180 cell-autonomous process based on chromosomal sex identity (CASI).

181 (aORs) after controlling for age, race, and sex in multivariate analysis (asthma aOR = 2.61 [95% CI

182 we describe a new technique used to identify sex in neonate turtles of two TSD species, a freshwater

183 Uptake was positively associated with female sex in the index patient (adjusted odds ratio [aOR] 1.56

184 There was equal representation by sex in the surveys (52% girls and 48% boys).

185 ly different functional requirements of both sexes in the new environment but also rapid sex-specific

186 We found little evidence that sex influenced the probability of an individual host bei

187 We find that, in NF1 mice of both sexes, inhibition increases strongly during the developm

188 l investigations taking both development and sex into account.

189 at autosomal trans-regulatory sequences with sex-limited effects are available to compensate for cis-

190 /mL]) were recruited, along with 61 age- and sex-matched (by cohort) healthy controls.

191 s) and 10 systemically healthy (SH) age- and sex-matched children (C) were enrolled in the study.

192 cocaine use disorder, compared with age- and sex-matched control subjects, based on previous imaging

193 m or dissection, in comparison with age- and sex-matched controls (1:10 for aortic aneurysm and 1:100

194 subjects with MDD as compared with age- and sex-matched HC.

195 Compared to age- and sex-matched nontransplant patients with chronic liver di

196 d retrospectively and compared with age- and sex-matched patients with svPPA (n = 70), bvFTD (n = 70)

197 th BCG at 6 pm and compared with 36 age- and sex-matched volunteers vaccinated between 8 am and 9 am.

198 k factors for OUD included younger age, male sex, Medicaid insurance, Medicare insurance, higher numb

199 toencephalography while human subjects (both sexes) monitored the orientation of a grating stimulus,

200 , 95% CI 1.29-1.33) after adjusting for age, sex, monthly income, geographic location and residential

201 rder was associated with younger age, female sex, more recent admitting years, presence of preexistin

202 several confounding factors, including male sex, NSAID coadministration, advanced age, and prior dia

203 Reporting the sex of biological material is critical for transparency

204 e isoform-specific effects in mice of either sex on cognition and synaptic plasticity.

205 personality trait constraint independent of sex or age.

206 between presence of incidental findings and sex or race/ethnicity among either cohort, and no correl

207 No sex- or race-based CAC interactions for ASCVD, CHD, and

208 creased with age to a similar extent in both sexes (P < 0.05), whilst MU firing rate progressively de

209 Compared to opposite-sex pairings, females in same-sex pairs vocalized when c

210 ed to opposite-sex pairings, females in same-sex pairs vocalized when closer to a social partner and

211 othesis that offspring prioritize their same-sex parent's experience.

212 were most pronounced for MSM with >10 recent sex partners, and partly explained by higher CMV seropre

213 No difference in sex, performance status, comorbidity, or body mass index

214 Age and sex played lesser roles.

215 complex, highly parameterized models in age/sex prediction across increasing sample sizes.

216 7% to 54.5%; P=0.0005) after controlling for sex, race, comorbidity, and cluster.

217 sociated death, and rates and proportions by sex, race/ethnicity, and birth year.

218 ter adjustment for year of colonoscopy, age, sex, race/ethnicity, and smoking history.

219 Conversely, sex ratio (SR) and sex-specific density explained 52.8%

220 hances our ability to measure neonate turtle sex ratios at population levels across nesting sites wor

221 Gametocyte sex ratios from qRT-PCR were compared with those from im

222 ights the need for a clear assessment of how sex ratios of organisms with TSD are affected.

223 expression analysis of genes described to be sex-related in vertebrates singled out an expected funct

224 vior, confirming the high variability of the sex-related pathway in vertebrates.

225 ned in the United States, yet disparities by sex remain.

226 esticular differentiation and female-to-male sex reversal in a manner that does not requireSry or Sox

227 omosome 11 that protected against B6.Y (POS) sex reversal.

228 enomic correlation in puberty timing between sexes (rg = 0.68) and identify 76 independent signals fo

229 Subgroup analyses were performed for sex, sample size, displacement duration, visa status, co

230 g cancer was identified for the variables of sex, smoking or study design.

231 sexes in the new environment but also rapid sex-specific adaptation.

232 e of postnatal nutrition in facilitating the sex-specific adipogenic programming in the IUGR offsprin

233 ific chromatin differences may contribute to sex-specific ageing in flies.

234 ergy metabolism and demonstrate the need for sex-specific approaches in obesity research and potentia

235 Using sex-specific blood and gastrointestinal parasite prevale

236 anges revealed that although VS induced many sex-specific changes in gene expression, it increased se

237 females and that loss of microRNAs leads to sex-specific changes in the microglial transcriptome and

238 This suggests that sex-specific chromatin differences may contribute to sex

239 ronmental conditions in interaction with the sex-specific costs of sexual selection.

240 how no behavioural abnormalities but do have sex-specific deficits in body mass and motor function.

241 Conversely, sex ratio (SR) and sex-specific density explained 52.8% (males) and 91.0% (

242 We investigated sex-specific differences in general and according to the

243 Overall, we find that sex-specific differences in T(reg) cells from VAT are de

244 ales, we examined whether H2A.Z cKO also has sex-specific effects on fear sensitization in the stress

245 agonist treatment after puberty onset exerts sex-specific effects on social- and affective behavior,

246 odel, calibrated to capture age-specific and sex-specific gaps in the scale-up of ART, to estimate th

247 We performed sex-specific GWAS of BE/EA in 3 separate studies and the

248 se risk for liver tumorigenesis in mice in a sex-specific manner.

249 e missed opportunities to uncover underlying sex-specific mechanisms.

250 Associations between sex-specific quintiles of DF intake and the risk of chro

251 This contributes to sex-specific regulation of excitability, [Ca(2+)](i), an

252 We found sex-specific response patterns despite similar behaviora

253 AAA, no studies have prospectively examined sex-specific risk factors, such as premature menopause a

254 The sex-specific role of murine Dusp8 in governing hypothala

255 Sex-specific synaptic connectivity is beginning to emerg

256 nin I assay to a high-sensitivity assay with sex-specific thresholds, in patients with suspected acut

257 ay help to unravel the mechanisms underlying sex-specific vulnerability in ALS-FTD.

258 ios (SMRs) were estimated with age-specific, sex-specific, and calendar year-specific US rates.

259 nine (CpG) sites and such an association was sex-specific.

260 the mechanisms of NMJ reinnervation in both sexes, specifically whether macrophage-derived vascular

261 A prenatal sex steroid environment of high prenatal testosterone an

262 general neuromodulators of memory processes, sex steroid hormones such as the potent oestrogen 17beta

263 health risks faced by individuals receiving sex steroid treatment.

264 he exposure and responsiveness of tissues to sex steroids varies among individuals and between the se

265 tory strategies-sexual dichromatism, age and sex-structured migration, and delayed plumage maturation

266 Calibration was fair in all race-sex subgroups (chi(2)<20).

267 developing rodent cerebellar cortex (of both sexes), there is a transient window when the dominant br

268 f veterans, we found increasing age and male sex to be significantly associated with increased risk o

269 rons in brainstem slices from mice of either sex to demonstrate that in addition to excitatory glutam

270 p that integrates food detection and genetic sex to dynamically modulate chemoreceptor expression and

271 and controls matched for age, education, and sex to ensure each group had at least 60 participants wi

272 ows larval Drosophila melanogaster of either sex to negotiate this exploration-exploitation transitio

273 rd ratios (HRs) for lung cancer incidence by sex, tobacco smoking, asbestos exposure, presence of asb

274 Human trafficking and child sex trafficking and sexual exploitation in particular ar

275 d with migraine with aura, young age, female sex, use of oral contraceptives and smoking habits.

276 mor pathology, and vascular invasion, female sex was associated with a 25% lower risk of post-liver t

277 Female sex was not an independent predictor of mortality at 10

278 res, number of previous treatments, age, and sex were not associated with CMBs.

279 significance of accounting for an organism's sex when studying fungal-bacterial-host dynamics.

280 nal cultures derived from embryos of unknown sex, whether BDNF-induced signaling cascades are altered

281 a single contraction level differed between sexes, which may reflect a greater tendency for females

282 omes and neuronal cultures of mice of either sex, while increasing the extracellular D-serine concent

283 tyrosine metabolites were increased in both sexes, while 1,5-anhydroglucitol levels decreased in mal

284 data from healthy human volunteers of either sex who received the NMDAR antagonist S-ketamine in a pl

285 a 12-month deferral since the donor last had sex with a man.

286 concentrated among 3.1 million men who have sex with men (MSM) and 1.1 million people who inject dru

287 igh-risk populations, including men who have sex with men (MSM) and transgender women, in Bangkok, Th

288 ange in blood donor deferral of men who have sex with men (MSM) from an indefinite to a 12-month defe

289 screening every 3-6 months for men who have sex with men (MSM) using HIV preexposure prophylaxis (Pr

290 a high-risk subset of cisgender men who have sex with men (MSM).

291 ds to determine HIV prevalence in men having sex with men in Brazilian cities and confirmed a high pr

292 Corresponding figures for men having sex with men were: 86%, 93%, 93%, 74%; for people who in

293 women, female sex workers, and men who have sex with men, include the importance of strategies for m

294 with sexual transmission among men who have sex with men.

295 the afferent innervation in gerbils of both sexes with computational modeling of a single cell.

296 ischarge characteristic differs according to sex, with female athletes progressing to a slower firing

297 y-duration relationship is different between sexes, with females sustaining a greater relative intens

298 prophylaxis (PrEP) use among cisgender male sex workers (MSWs), a high-risk subset of cisgender men

299 ence in a high-risk cohort of Zambian female sex workers and single mothers conducted from 2016 to 20

300 es, adolescent girls and young women, female sex workers, and men who have sex with men, include the