ライフサイエンスコーパス: sex difference

1 sorder in women may need to account for this sex difference.

2 y after AVR and to examine whether there are sex differences.

3 d control groups in male and female revealed sex differences.

4 s an integral component for generating these sex differences.

5 and ethnic groups, with significant age and sex differences.

6 ies, and also uncover previously undescribed sex differences.

7 y to segregate competing speech using talker sex differences.

8 ntensive care patients evidenced independent sex differences.

9 There were no significant age or sex differences.

10 preceded the recent explosion of interest in sex differences.

11 ies divergence is needed when modeling human sex differences.

12 unted for some, but not all, of the observed sex differences.

13 linked to robust psychological or behavioral sex differences.

14 f the mouse DRG with the goal of identifying sex differences.

15 s, and for other behaviors that show average sex differences.

16 ons of adverse coronary plaque features, and sex differences.

17 rmones are hypothesized to underlie observed sex differences.

18 polygenic hazard scores with no evidence for sex differences.

19 nitive and socioemotional scores and explore sex differences.

20 draw attention to the surprising lacunae in sex differences across attack and defense.

21 ame prenatal exposures have consequences for sex differences across multiple organ systems that, in p

22 This study analyzed sex differences among cornea specialists with regards to

23 menopausal women versus men, with attenuated sex differences among post-menopausal women not taking h

24 In normal physiological condition, sex difference and E2 treatment did not affect the ratio

25 ic activity and hypertension with a focus on sex differences and changes with age in humans.

26 Sex differences and evolutionary differences are critica

27 More research is needed to better understand sex differences and further improve advanced heart failu

28 osome differences are reflective of germline sex differences and have been used extensively to learn

29 Sex differences and hormonal effects in presumed cisgend

30 We discuss sex differences and sex similarities in human sexual psy

31 Sex differences and social context independently contrib

32 lts underline the pervasiveness of molecular sex differences and strengthen the call for increased co

33 Policy-makers should pay attention to sex differences and types of social capital when leverag

34 itions (i.e., with and without target-masker sex differences and/or with and without spatial cues).

35 nce of studying both sexes, of understanding sex differences (and similarities) in response to ELA, a

36 een strains, in terms of behavioral changes, sex differences, and the intracranial calcifications tha

37 uman brain have found only a small number of sex differences, and these differences are generally sma

38 males, but the mechanisms that underlie this sex difference are not completely understood.

39 Quantifying whether such sex differences are also pervasive in wild mammals is a

40 The extent to which sex differences are conserved at the molecular level acr

41 y, this contrasts with rodent studies, where sex differences are focused in deep, ancestral limbic re

42 monly require more parental resources, these sex differences are not currently incorporated into evol

43 Thus, dopamine related sex-differences are likely mediated by secondary mechani

44 We also observed a sex difference as well as a cross-sex shift in gay men w

45 Several HSMs showed sex differences at both time points.

46 ns at birth and in non-twin adults to detect sex differences at different stages of life, and show th

47 We observed a sex difference between heterosexual men and women in the

48 Sex differences between men and women have allowed for t

49 r species, and have reported that some brain sex differences correlate with sexual orientation or gen

50 Sex differences emerged during the dark (active) phase w

51 Sex differences exist in the interactions between IVD de

52 Studies also suggest sex differences exist in the neural correlates of mental

53 ight the recent evidence that microglia have sex differences, factors that contribute to these differ

54 Linear regression was used to examine sex differences for the top ten HSMs, adjusting for age,

55 Finally, we noted that most behavioral sex differences had been reported in Sprague-Dawley rats

56 Sex differences have been observed in multiple facets of

57 However, sex differences have not been fully examined in applicat

58 model organism for studying neurobiological sex differences-have established: 1) highly consistent s

59 The factors that govern such sex differences, however, remain poorly understood.

60 asite prevalence is an unlikely predictor of sex difference in adult mortalities, not withstanding sa

61 (GWAS) revealed that genes with an intrinsic sex difference in ECs are enriched for coronary artery d

62 und that genes that present with an acquired sex difference in ECs are more likely to be targets of s

63 anisms since the findings correlate with the sex difference in ischemic events and mortality and thus

64 Prior work has also suggested a potential sex difference in PACAP effects due to differential estr

65 Whether there is a sex difference in pulmonary innate immune TLR4 signaling

66 iture and substrate utilisation, suggests no sex difference in response to exposure to extreme enviro

67 This sex difference in social play is highly conserved across

68 The data reveal a sex difference in the adaptation of the PSD scaffold to

69 In line with previous work, we find a robust sex difference in the classic forced-choice jealousy tas

70 whether such differences correlate with the sex difference in the disease course of COVID-19, is cur

71 but not female rats, indicating an important sex difference in the function of this brain pathway.

72 Collectively, these data reveal a marked sex difference in the impact of obesity on the sympathoe

73 To investigate the generalizability of a sex difference in the requirement for PKA in synaptic po

74 work on the topic has focused on a proposed sex difference in the type of jealousy (sexual or emotio

75 We found little or no sex difference in these measures, suggesting sexual cong

76 No sex difference in time to task failure was observed in e

77 hatic influx decreases with age there was no sex difference in total influx or subregion-dependent tr

78 ce in triglyceride storage and abolishes the sex difference in triglyceride breakdown via strongly ma

79 find that loss of bmm largely eliminates the sex difference in triglyceride storage and abolishes the

80 However, males suppress this sex difference in two contexts: juvenile males exhibit h

81 cations including power analysis considering sex difference in variance.

82 We demonstrate a circuit-specific sex difference in vHPC-NAc neurons that is dependent on

83 Here, we explored sex differences in (a) cell proliferation (5'-bromo-2'-d

84 with MI and compared these associations with sex differences in a control group without a history of

85 Significant sex differences in achieving the rank of full professor

86 There are clinically relevant sex differences in acute and chronic pain mechanisms, bu

87 While many studies have revealed sex differences in adipocyte cell signaling and physiolo

88 Sex differences in adipose tissue distribution and funct

89 nce Images (MRIs), identifying morphological sex differences in adolescence from those of the Nationa

90 the contrary, we do not find any consistent sex differences in aging rates.

91 There are sex differences in arterial stiffness and neural control

92 estions regarding transcriptomic analysis of sex differences in ASD.

93 Sex differences in associations with subcutaneous adipos

94 ggest that sex hormones play a role in known sex differences in asthma in adults.

95 Despite well-described sex differences in asthma incidence, there remains uncer

96 Underlying biological mechanisms involved in sex differences in asthma status changes from pre- to po

97 Although sex hormones may explain sex differences in asthma, their role is unclear.

98 This was accompanied by sex differences in basal theta and gamma oscillations in

99 c, phasic inhibition have been implicated in sex differences in binge drinking.

100 onstitute an anatomic substrate for observed sex differences in binge-eating disorder.

101 Sex differences in biomarker profiles were most pronounc

102 hat prenatal OP exposure was associated with sex differences in brain activation during a language co

103 cal foci, 2) a preponderance of regional GMV sex differences in brain circuits for social and reprodu

104 ive differences as a framework to understand sex differences in brain development associated with psy

105 x differences in prevalence, suggesting that sex differences in brain development may underlie differ

106 Here we review the evidence for sex differences in brain structure, white matter organiz

107 produce self-sperm.) Essentially all somatic sex differences in C. elegans are governed by the master

108 ar etiologies that may underpin the dramatic sex differences in cancer incidence and outcome.

109 istribution and function are associated with sex differences in cardiometabolic disease.

110 istration paradigm in mice recapitulated the sex differences in cocaine intake and relapse demonstrat

111 in Egr3 expression in D2-MSNs contributes to sex differences in cocaine relapse.

112 Humans display reproducible sex differences in cognition and behavior, which may par

113 ning and memory, and a possible cause of the sex differences in cognitive development and function.

114 Sex differences in complement protein levels may help to

115 etwork analysis revealed that the consistent sex differences in connectivity and related cognitive as

116 This contrasts with human studies, where sex differences in cortical regions have been reported b

117 nd a female genome in each species and using sex differences in coverage to identify the PAB.

118 Student t test was used to evaluate sex differences in cRNFL thickness globally and at each

119 We aimed to test if sex differences in CRT response at lower QRSd thresholds

120 Sex differences in CVD mortality rates were the greatest

121 Sex differences in demographics, clinicopathologic chara

122 After briefly reviewing some observed sex differences in depression, we discuss how sex might

123 This finding may be related to sex differences in diaphragm muscle metabolism, such as

124 hensive and mechanistic understanding of how sex differences in dopamine function manifest will be pa

125 e as potential targets for the expression of sex differences in dopamine regulation in both ovarian h

126 X(2) stimulations, there were no regional or sex differences in dopamine release.

127 It is largely unknown if sex differences in DSD exist in auditory and visual brai

128 ata support the possibility of developmental sex differences in DSD in visual and auditory regions an

129 We observed substantial sex differences in effects of 15 metabolites with partia

130 s growth and puberty and may orchestrate the sex differences in endocrine function observed during pu

131 Sex differences in endothelial cell (EC) biology may ref

132 ind little support for significant gender or sex differences in executive function.

133 components of animals life that may include sex differences in exposure to predators, immune capacit

134 We identified 162 genes with robust sex differences in expression.

135 tly localized in the temporal lobe, however, sex differences in extra-temporal tau highlights the pos

136 physiological mechanisms that contribute to sex differences in fat storage.

137 APOEepsilon4-moderated sex differences in FTP-signal were only found in the lat

138 ical school-specific fixed effects to assess sex differences in full professorship by specialty and t

139 It exhibits well-established sex differences in GABAergic inhibitory neurotransmissio

140 We generated a catalog of sex differences in gene expression and in the genetic re

141 We demonstrated that sex differences in gene expression could be influenced b

142 methylation of the X chromosome can lead to sex differences in gene expression during immune respons

143 We further determined that sex differences in gene expression levels could be relat

144 However, potential sex differences in genetic associations with BE/EA remai

145 es in gene expression could be influenced by sex differences in genetic regulation for six genes (e.g

146 more effective in females and paralleled by sex differences in glutamatergic signaling.

147 Sex differences in h-indices were not seen at each acade

148 fferences in OA prevalence are attributed to sex differences in hip shape.

149 Specifically, sex differences in hormonal influences and neural circui

150 ng-transcriptomic analyses, we show that GMV sex differences in human adulthood are specifically and

151 there is a need for better understanding of sex differences in immune function and opioid pharmacoki

152 Further, we propose that sex differences in immune function are mediated, at leas

153 their recent article, Takahashi et al. found sex differences in immune responses to SARS-CoV-2 and th

154 We propose that sex differences in immunopathogenesis will inform mechan

155 crophages, constituting a novel component of sex differences in innate immune control of HIV-1.

156 We previously reported sex differences in innate susceptibility to Staphylococc

157 lodynia and DRG gene expression, even though sex differences in IVD measurements were limited.

158 e hippocampus of each sex and tested whether sex differences in kinase signaling extend to LTP.

159 (PTSD) that is observed in women may involve sex differences in learned fear inhibition and medial pr

160 ults add to growing evidence indicating that sex differences in learned fear inhibition are associate

161 Our analyses suggest that the magnitude of sex differences in mammalian mortality patterns is likel

162 Evidence about sex differences in management and outcomes of critical l

163 Together, these data present evidence that sex differences in MC phenotype and resulting disease se

164 The importance of investigating sex differences in mechanisms of cardiovascular function

165 In addition, sex differences in median adult lifespan and aging rates

166 This review describes how sex differences in microcircuit regulatory mechanisms ca

167 Could these sex differences in microglia explain the sex differences

168 ng those with ADHD, we found no evidence for sex differences in mind wandering and among those withou

169 rders may be more effective if designed with sex differences in mind.

170 xes and to investigate its role in potential sex differences in models of depression.

171 Nevertheless, the real impact of sex differences in movement disorders remains under-reco

172 Secondary objectives investigated potential sex differences in MRI parameters and relationship with

173 Knowledge on sex differences in myocardial perfusion, blood volume (M

174 se findings provide mechanistic insight into sex differences in myocardial physiology.

175 Our findings catalog preparation-dependent sex differences in neuronal gene expressions in sensory

176 Our results indicate that there are distinct sex differences in neutrophil biology related to respons

177 s the sensitivity to pain and is involved in sex differences in nociception.

178 Our results demonstrate sex differences in nociceptor-enriched translatomes and

179 om-effects meta regression estimated whether sex differences in not enrolling ("screen out") varied b

180 om-effects meta regression estimated whether sex differences in not enrolling ("screen out") varied b

181 Our results may explain sex differences in obesity-mediated disorders caused by

182 -enriched translatomes and reveal unexpected sex differences in one of the oldest known nociceptive s

183 these results suggest that the expression of sex differences in opioid reinforcement depends upon the

184 luted Ensure((R)) choice procedure to assess sex differences in opioid reinforcement.

185 Sex differences in outcome include superior maintenance

186 en, but the biological mechanisms underlying sex differences in pain remain poorly understood.

187 sting for the number of visits and patients, sex differences in payments remained significant for all

188 n particular, little is known about possible sex differences in peripheral nociceptors, the fundament

189 e-range of functions and disorders that show sex differences in phenotype and/or incidence.

190 rrent study supports the existence of robust sex differences in prefrontal and striatal resting state

191 early developing brain as well as potential sex differences in prenatal susceptibility, and 4) evalu

192 Many of these illnesses have substantial sex differences in prevalence, suggesting that sex diffe

193 These findings highlight the importance of sex differences in progenitor biology and the developmen

194 These sex differences in promotions and appointments did not d

195 Here, we explore sex differences in proximal femur shape in a cohort of a

196 Given known sex differences in PTSD prevalence and cardiovascular di

197 Specifically described are sex differences in receptors for the stress neuropeptide

198 This study assessed sex differences in recurrent MI, recurrent CHD events, a

199 behavior, which may partly reflect intrinsic sex differences in regional brain organization.

200 r understanding of the mechanisms underlying sex differences in renal pathophysiology, disease develo

201 To investigate the sex differences in response to renal injury, we examined

202 Sex differences in responses to intestinal ischemia-repe

203 information about the mechanisms supporting sex differences in risk taking and may prove useful in u

204 iments was to test the extent to which these sex differences in risky decision making are mediated by

205 The reason for these sex differences in RRD repair remains unknown and requir

206 f 8 months, particularly previously observed sex differences in rsFC.

207 Finally, our data suggested sex differences in serine-312 phosphorylation of IRS-1 i

208 potential underlying biological etiology for sex differences in stress-related anxiety disorders that

209 oviding insight into mechanisms of prominent sex differences in stress-related memory disorders, such

210 While sex differences in stressor-induced plasma corticosteron

211 We investigated sex differences in subcutaneous adipose tissue transcrip

212 suggests profound biological foundations for sex differences in survival.

213 The present study examines sex differences in synaptic plasticity and cellular acti

214 The goal of this study was to examine sex differences in tau distribution across the brain of

215 beta-amyloid (Abeta)-moderated sex differences in tau signal were localized to medial a

216 Confirming previous work, we find marked sex differences in THC metabolism, including a female-sp

217 oductive hormones on cerebral blood flow and sex differences in the ability of the cerebral vasculatu

218 c HIV-1 infection, but little is known about sex differences in the acute phase, or how disparities i

219 While substantial work has focused on sex differences in the anatomy of dopamine neurons and r

220 In particular, we focus on sex differences in the brain as they relate to anxiety,

221 siological mechanism for previously observed sex differences in the comorbidity of major depression a

222 Sex differences in the control of hypertension, diabetes

223 Thus, these studies reveal sex differences in the effects of junk-food on NAc synap

224 We did not observe evident sex differences in the frequency of persistent HIV in re

225 related genes in subcutaneous adipose tissue sex differences in the genetic and environmental regulat

226 n gene expression levels could be related to sex differences in the genetics of gene expression regul

227 the consistency, causes and consequences of sex differences in the human brain are poorly characteri

228 using human autopsy material have found some sex differences in the human brain similar to those seen

229 ngs provide an extensive characterization of sex differences in the human transcriptome and its genet

230 This review examines known sex differences in the immune system and their relations

231 s regulating social reward may contribute to sex differences in the incidence of a large number of ps

232 Sex differences in the manifestations of Alzheimer's dis

233 scriptomic analysis, we found that molecular sex differences in the MeA are specifically represented

234 n memory in males will be discussed, as will sex differences in the molecular mechanisms that regulat

235 ens, our work illustrates the vast extent of sex differences in the molecular mechanisms underlying p

236 We discuss the possibility that sex differences in the motivations and fitness implicati

237 Sex differences in the neural mechanisms regulating soci

238 Sex differences in the neurovasculature response post-TB

239 We hypothesised that there might be sex differences in the optimal dose of ACE inhibitors or

240 taking and may prove useful in understanding sex differences in the prevalence of psychiatric disease

241 in the nucleus accumbens (NAc) in promoting sex differences in the reinforcing effects of nicotine.

242 Sex differences in the relation between BMI (in kg/m2) a

243 AIs are also used by men, yet sex differences in the reported side effects have not be

244 VN in male and female rats and characterized sex differences in the RLN3 innervation of the PVN.

245 Many chronic pain conditions show sex differences in their epidemiology.

246 In addition, they indicate sex differences in thermoregulatory responses and will i

247 Further, sex differences in these comorbidities are substantial.

248 d on understanding stimulus-driven behavior, sex differences in these processes, and the neural circu

249 We found some sex differences in those animals highlighting the import

250 that variation in flight performance drives sex differences in time-activity budgets and may lead th

251 Sex differences in trait variability, however, are yet t

252 ivalently in females and males contribute to sex differences in traits.

253 s a relative dearth of information regarding sex differences in transcript abundance and regulation.

254 de lipase brummer (bmm) in the regulation of sex differences in triglyceride homeostasis.

255 and 95% confidence intervals (CIs) assessing sex differences in various characteristics and cardiovas

256 to test contributions of gonadal hormones to sex differences in vHPC afferents.

257 Here we examined sex differences in viral loads, SARS-CoV-2-specific anti

258 While sex differences in vulnerability have been identified wi

259 Here we report a pan-cancer analysis of sex differences in whole genomes of 1983 tumours of 28 s

260 e of sleep in adolescent obesity and suggest sex-differences in this relationship that warrant future

261 uences from chronic TRAP exposure, including sex differences indicating females may be more susceptib

262 of infection, but little is known about how sex differences influence acute HIV-1 infection.

263 blood pressure-associated subscore exhibited sex differences (interaction P=0.0004 per SD increase in

264 Here we determined if these sex differences involve altered mPFC function.

265 This sex difference is reversed at menopause, when women deve

266 Biological sex differences may manifest themselves in susceptibilit

267 ole dorsal root ganglion (DRG) have revealed sex differences, mostly in immune cells.

268 it 1-h after the start of drinking, with no sex differences observed at any time point.

269 ral, animal models of NAFLD recapitulate the sex differences observed in patients, with more severe s

270 Moreover, the neural basis for the sex differences observed in the clinical arena is unknow

271 pients of male donor kidneys, with a similar sex difference of 4.1% (95% CI = 2.1%-6.1%, P < 0.001) o

272 to the magnitude, location, and direction of sex differences of local gray matter volume (GMV) in the

273 lation and stroke and to establish potential sex differences of such associations in a cohort of endu

274 Furthermore, there were sex differences on measures of incentive salience attrib

275 grief in bereaved parents and about possible sex differences related to such factors.

276 ource and implications of this epidemiologic sex difference remain unclear, as does the practical sig

277 allocation) consistent with the direction of sex differences reported in the clinical literature.

278 We also find that genetic sex differences result in specialized flavonoid metaboli

279 om KwaZulu-Natal, South Africa, fetal immune sex differences resulting in a 1.5-2-fold increased fema

280 alized environments exacerbate these evolved sex differences, resulting in the increasing risk of aut

281 discuss evidence both that there are latent sex differences revealed by ELS and that ELS itself prod

282 Furthermore, sex differences seem to be present in language lateraliz

283 ese sex differences in microglia explain the sex differences seen in neurodegenerative diseases?

284 data from both stages of life, we identified sex differences that are present at birth and maintained

285 e practical significance of the multitude of sex differences that have been reported in brain structu

286 Using this approach, we have identified sex differences that were not detected by previous studi

287 cted toward adult sex hormones as drivers of sex differences, that female sex bias in MC-associated d

288 To evaluate if Egr3 contributed to sex differences to cocaine relapse, we conducted these p

289 features of immunity and highlight potential sex differences underlying COVID-19 severity.

290 beats(-1) mmHg(-1) , P = 0.007), while this sex difference was observed when assessed with burst are

291 ssed relative to maximal ramp test power, no sex difference was observed.

292 ether circulating hormones are driving these sex differences, we ovariectomized WT and Npas2 mutant f

293 Sex differences were consistent across primary and secon

294 The sex differences were even larger in the later cohorts wi

295 Sex differences were noted in control mice, in which fem

296 Surprisingly, no sex differences were observed among these associations.

297 l children, suggesting early-life origins of sex differences which have yet to be explored.

298 include possible mechanisms underlying these sex differences with particular focus on synaptic transm

299 Sex differences within academic ranks and h-indices are

300 cally significant concentration of human GMV sex differences within brain regions that subserve face