ライフサイエンスコーパス: sexual development

1 cused on genes involved in gametogenesis and sexual development.

2 ved to restrict genetic recombination during sexual development.

3 n in fungi to specify cell types and control sexual development.

4 rucial role in regulating cGMP levels during sexual development.

5 between yeast growth and filamentous asexual/sexual development.

6 hormone receptor HR39 is also essential for sexual development.

7 calcium from hard to soft tissues during its sexual development.

8 y from a paternal copy, that triggers female sexual development.

9 o secrete LHRH, the neuropeptide controlling sexual development.

10 d by glutamatergic neurons to control female sexual development.

11 transcriptional machinery controlling female sexual development.

12 -enriched transcripts, we focused on somatic sexual development.

13 d candidates to encode regulators of somatic sexual development.

14 e somatic gonad that regulates male germline sexual development.

15 NT4 has been shown to be important in female sexual development.

16 nce and resistance, cell wall integrity, and sexual development.

17 the single mating type locus (MAT) controls sexual development.

18 ntral role in coordinating hyphal growth and sexual development.

19 nstream of GprD-mediated negative control of sexual development.

20 hereas smaller transcripts accumulate during sexual development.

21 imary role of GprD is to negatively regulate sexual development.

22 and link nuclear export to the regulation of sexual development.

23 ific gene, the complex induces hermaphrodite sexual development.

24 and astroglial input to LHRH neurons during sexual development.

25 ike protein, in meiotic silencing and normal sexual development.

26 the hypothalamic neuropeptide that controls sexual development.

27 anches that play crucial roles in regulating sexual development.

28 may be an essential step in Aalpha-regulated sexual development.

29 ine in the wild could be at risk of impaired sexual development.

30 ha in a cells is sufficient to drive a/alpha sexual development.

31 in conidia and under conditions that favour sexual development.

32 gger a pathway of fertilization required for sexual development.

33 rectly or indirectly, all genes required for sexual development.

34 nalling molecule Wnt-4 is crucial for female sexual development.

35 hormone (LHRH), the neuropeptide controlling sexual development.

36 least some of the same mechanisms to control sexual development.

37 the neuroendocrine brain controls mammalian sexual development.

38 family member TRA-1 is necessary for normal sexual development.

39 Dmrt1 may also play a role in avian sexual development.

40 Primary safety measures were growth and sexual development.

41 on, cpsA is necessary for normal asexual and sexual development.

42 l cycle and shown to be essential for normal sexual development.

43 otes results in abnormalities of somatic and sexual development.

44 ot reveal abnormalities during vegetative or sexual development.

45 n appropriately stressed that most resort to sexual development.

46 n factor complex that commits mated cells to sexual development.

47 ed how this pathway may regulate alternative sexual development.

48 e sex determination can reveal new actors in sexual development.

49 m cells across intraerythrocytic asexual and sexual development.

50 invasion, and transmission during Plasmodium sexual development.

51 nt only in females, where it promotes female sexual development.

52 agues identified genes required for parasite sexual development.

53 may be related to its functions during early sexual development.

54 rved ones shared with species showing simple sexual development.

55 role of ApiAP2 proteins in malaria parasite sexual development.

56 r vegetative growth, conidial production and sexual development.

57 nvolved in toxin processing and disorders of sexual development.

58 non-coding mutations underlying disorders of sexual development.

59 ecific expression of AMD1 at later stages of sexual development.

60 otein, Pum1, for hyphal morphogenesis during sexual development.

61 hereas cats serve as the definitive host for sexual development.

62 e into gametocytes ready for continuation of sexual development.

63 r beyond their previously understood role in sexual development.

64 een), is a major site of parasite growth and sexual development.

65 ociated with pathologies of reproduction and sexual development.

66 MID produced functional sperm packets during sexual development.

67 uency of switching from the asexual cycle to sexual development.

68 y genes (feminizer and doublesex) that guide sexual development.

69 ondrial activity and lipid metabolism during sexual development.

70 associated with matA(HMG) regulation during sexual development.

71 A-1-binding sites results in defects in male sexual development.

72 ts is perhaps the least understood aspect of sexual development.

73 sion changes that occur over time throughout sexual development.

74 duction in conidiation, and complete loss of sexual development.

75 The androgen receptor (AR) regulates male sexual development.

76 pathway operates to defend the genome during sexual development.

77 y quelling, in meiotic silencing, and normal sexual development.

78 produces steroid hormones that regulate male sexual development.

79 omains of both Sxi proteins are required for sexual development, a departure from related fungi.

80 uberty, a complex biologic process involving sexual development, accelerated linear growth, and adren

81 genes, including numerous key regulators of sexual development across land plants.

82 major differences in the genetic control of sexual development among animal lineages, the doublesex/

83 microencapsulated diets facilitate improved sexual development and 12 x greater omega-3 levels in oy

84 o distinct phenotypes: nutrition-insensitive sexual development and a growth defect at high levels of

85 zygous-fertile phenotype uncouples MSUD from sexual development and allows us to demonstrate that bot

86 the ability of enkephalins to disrupt insect sexual development and also suggests the existence of co

87 in NCU09915 (fsd-1) were defective in female sexual development and ascospore maturation.

88 In addition, it has a potential role in sexual development and bile acid transport, and it is as

89 ecific transcription factor involved in male sexual development and bone formation.

90 chanism of species specificity for T. gondii sexual development and break the species barrier to allo

91 ype locus of Schizophyllum commune regulates sexual development and contains the code for two protein

92 ions about sexuality to help promote healthy sexual development and decision making.

93 pproach provides a new resource for studying sexual development and demonstrates that exploiting the

94 ypothalamic expression of genes required for sexual development and deregulation of a gene involved i

95 We present a unified model for alternative sexual development and discuss the implications for esta

96 produce hyphae reminiscent of early steps in sexual development and display upregulation of genes ass

97 e can replace male worms to stimulate female sexual development and egg laying.

98 transcriptional modules and exon usage along sexual development and expanded it to include malaria pa

99 unexpected features of the initial steps of sexual development and extend the current view of this p

100 o inhibit transcription of genes involved in sexual development and gluconeogenesis, including the fb

101 n receptor (AR) plays a central role in male sexual development and in normal and malignant prostate

102 QIP is crucial for sexual development and is shown to colocalize with other

103 studies are essential to understanding human sexual development and its disorders.

104 o the insect gene doublesex, are integral to sexual development and its evolution in many metazoans.

105 ated with this axis can result in defects in sexual development and maturity.

106 O-acetyltransferase, which is important for sexual development and plant infection.

107 cts of water temperature and EDC exposure on sexual development and population viability of inbred an

108 protein 1 (SMTNL1) is a key factor governing sexual development and pregnancy induced adaptations in

109 ings define a new conserved pathway in which sexual development and pregnancy mediate smooth and stri

110 androgen receptor (AR) is critical for male sexual development and prostate cancer.

111 Surprisingly, sexual development and reproduction in mutant animals we

112 The LHR has an essential role in sexual development and reproductive function, and its tr

113 POR mutation A287P presents with disordered sexual development and skeletal malformations.

114 Second, sexual development and Sry expression levels were determ

115 of a paternal genome is required for female sexual development and suggest a genomic imprinting mech

116 culture conditions that support schistosome sexual development and sustained egg production in vitro

117 nrichment and pathway analyses shed light on sexual development and the biosynthesis of sesquiterpeno

118 Dmrt1 is likely to play a role in vertebrate sexual development and therefore that DM domain genes ma

119 ceRNA crosstalk mediated by ncRNAs modulates sexual development and unveils a novel regulatory mechan

120 slational repression of messenger RNA during sexual development, and a 47-base 3' untranslated region

121 pleiotropic effects on growth, conidiation, sexual development, and appressorium formation.

122 formation of female reproductive structures, sexual development, and meiosis.

123 These two genes control similar aspects of sexual development, and the male isoform of DSX can subs

124 oteins are essential for growth, asexual and sexual development, and virulence in both animal and pla

125 elated to invasion, asexual replication, and sexual development; and (iv) stage-specific.

126 Our findings suggest that genes involved in sexual development are also important in mammalian disea

127 The potential roles of ASW and Hint in avian sexual development are discussed elsewhere.

128 Commitment to and completion of sexual development are essential for malaria parasites (

129 served as dsx-related genes that function in sexual development are found throughout the animal kingd

130 he possible role of a rhamnogalacturonase in sexual development are presented.

131 rimary sex-determining signals that initiate sexual development are remarkably diverse, ranging from

132 master switch, is on in females and controls sexual development as a splicing and translational regul

133 on master switch, Sex-lethal (Sxl), controls sexual development as a splicing and translational regul

134 isplay upregulation of genes associated with sexual development as well as others encoding lipases an

135 During sexual development ascomycete fungi produce two types of

136 of phoA resulted in a switch from asexual to sexual development (at pH 8), or the absence of developm

137 isits is recommended to allow discussions of sexual development, behavior, and risk reduction.

138 gin is a poorly understood disorder of human sexual development, brought about by the premature activ

139 es require an opposite-sex partner for their sexual development but discard the partner's genome befo

140 Xanthones are not required for sexual development but exert antifeedant effects on fung

141 mplicated in the control of several genes in sexual development, but its function in gonad formation

142 a conserved role(s) for Dmrt1 in vertebrate sexual development, but there has been no functional ana

143 hways through an interaction with Msa2p, and sexual development by modulating Ran1p/Pat1p.

144 In males, SF-1 participates in sexual development by regulating expression of the polyp

145 Thus, TRA-1 coordinates sexual development by reinforcing the sex-determination

146 treatment also imposes selection pressure on sexual development by shortening infection length and re

147 th a variety of parasite processes including sexual development, cell invasion, antigenic variation a

148 duct syndrome (PMDS) is a 46,XY disorder of sexual development characterized by the persistence of M

149 Mammalian sexual development commences when fetal bipotential prog

150 d the transition from asexual development to sexual development compared to the wild-type strain.

151 -expressed in the charcoal and light-induced sexual development conditions.

152 rental species in the downstream pathways of sexual development could explain sex reversal, sterility

153 mporal genetic factors early and late in the sexual development cycle.

154 s within SF1 underlie different disorders of sexual development (DSD), including sex reversal, sperma

155 n are derepressed for fbp1 transcription and sexual development even while growing in a glucose-rich

156 this transcriptional activator functions in sexual development, filamentous growth, and pathogenicit

157 Factor 1 (VF1), that is essential for female sexual development following pairing with a male worm.

158 PBANKA_143750, which account for the loss of sexual development frequently observed in parasites tran

159 2-g (PF3D7_1222600), the master regulator of sexual development, from an epigenetically silenced stat

160 hormone (LHRH), the neuropeptide controlling sexual development, from hypothalamic neuroendocrine neu

161 es for male and female mating locus genes in sexual development, gamete fitness and reproductive succ

162 y of transcription factors whose function in sexual development has been well studied in invertebrate

163 y of transcription factors whose function in sexual development has been well studied.

164 xual regulator and suggest how regulation of sexual development has evolved in distinct ways in diffe

165 d regulatory pathways involved in Plasmodium sexual development have been of great interest in recent

166 Genes previously implicated in mammalian sexual development have either a male- or female-specifi

167 conditions - growing on charcoal, and during sexual development - identified modules of genes that ar

168 hway can have deleterious effects, including sexual development impairment, spontaneous abortion, and

169 y of the imprinted gene would result in male sexual development in a biparental diploid embryo.

170 a model in which Sxi1alpha and Sxi2a control sexual development in a homeodomain-dependent manner by

171 fore that DM domain genes may play a role in sexual development in a wide range of phyla.

172 to coordinate a balance between asexual and sexual development in A. nidulans.

173 etabolism and hyphal growth, while represses sexual development in A. nidulans.

174 We examined the effects of atrazine on sexual development in African clawed frogs (Xenopus laev

175 has been co-opted during evolution for male sexual development in amniotes.

176 The process of sexual development in animals is modulated by a variety

177 ieve the filamentous morphotype required for sexual development in Cryptococcus.

178 ing factors repress translation and modulate sexual development in different tissues of C. elegans.

179 latory genes controls all aspects of somatic sexual development in Drosophila melanogaster.

180 demonstration that one gene family controls sexual development in Drosophila, C. elegans, and verteb

181 nservation of the role of DM domain genes in sexual development in lophotrochozoans and suggest one m

182 At birth, sexual development in males with a mutation in Wnt-4 app

183 A basic tenet of sexual development in mammals is that genetic sex--deter

184 with DM domains may therefore also regulate sexual development in mammals.

185 ir diet with linoleic acid allowed T. gondii sexual development in mice.

186 anding of the genetic programs that initiate sexual development in mosquitoes.

187 act downstream of these switches to control sexual development in most animal species.

188 positively as a transcriptional regulator of sexual development in Neurospora.

189 Rum1 act jointly to inhibit Cdc2 and promote sexual development in nitrogen-starved cells.

190 on factor MAT1-1-1 was discovered to control sexual development in P. chrysogenum.

191 commitment of asexually replicating forms to sexual development in Plasmodium berghei, a malaria para

192 pc1 also has an important role in regulating sexual development in S. pombe.

193 loci that determine mating type and regulate sexual development in Schizophyllum commune.

194 ities between the abnormalities of embryonic sexual development in Sfrp1(-/-)Sfrp2(-/-) embryos with

195 Northern analysis suggests that faster sexual development in the basA mutant might be due to a

196 t triggers asexual development and represses sexual development in the fungus Aspergillus nidulans.

197 Eight genes that are upregulated during sexual development in the heterothallic oomycete, Phytop

198 e velvet gene, veA, co-ordinates asexual and sexual development in the homothallic fungal species Asp

199 encode MAPKK kinases that are necessary for sexual development in these organisms.

200 es serve as a foundation for deeper study of sexual development in this pathogen and identification o

201 group (LG) 19, which controls male or female sexual development in threespine sticklebacks.

202 Sexual development in Toxoplasma gondii is a multistep p

203 ls shown previously to synergistically alter sexual development in turtles also synergized in the YES

204 , nitrogen starvation initiates a program of sexual development in which cells express mating pheromo

205 and educational strategies to ensure healthy sexual development in young people.

206 ble of driving both early and late stages of sexual development, including gametogenesis.

207 domain and they regulate similar aspects of sexual development, including yolk protein synthesis and

208 Age, sexual development, irritable bowel syndrome subtype, st

209 Sexual development is controlled by the homeodomain tran

210 aled that the regulatory pathway controlling sexual development is far from linear and that it contai

211 Here we show that under conditions where sexual development is inhibited, a approximately 17-fold

212 In homozygous asd-I crosses, sexual development is initiated and large numbers of nor

213 Early sexual development is normal in ob/ob females; however,

214 eleasing hormone (GnRH) gene, which controls sexual development, is regulated by the POU protein SCIP

215 different mating types regulate a pathway of sexual development leading to mushroom formation and mei

216 ing fungal pathogen Cryptococcus neoformans, sexual development leads to the production of spores (su

217 al for an understanding of how they regulate sexual development, morphogenesis, differentiation and a

218 During sexual development, Neurospora crassa inactivates genes

219 t Axl2 is also involved in the regulation of sexual development, not only in A. nidulans, but also in

220 We determined that T. gondii sexual development occurs when cultured feline intestina

221 I highlight a number of common themes in the sexual development of different taxa, discuss how Dmrt g

222 Here we have determined that the sexual development of female mice is profoundly affected

223 ity and dynamics at the isoform level in the sexual development of fission yeast.

224 Starvation-independent sexual development of ncs1Delta was also complemented by

225 quence similarity to genes that regulate the sexual development of nematodes and insects.

226 transcription-factor characterization during sexual development of the human fungal pathogen Cryptoco

227 undant role for Sfrp1 and Sfrp2 in embryonic sexual development of the mouse.

228 ng transcription at those loci involved with sexual development of the parasite.

229 ata indicate a novel role for lactic acid in sexual development of the parasite.

230 is suggests a critical role for Pfg27 in the sexual development of the parasite.

231 ation gene tra-3 is required for the correct sexual development of the soma and germ line in hermaphr

232 eparate roles for GATA4 and FOG2 proteins in sexual development of the testis we have ablated the cor

233 DM domain proteins may also play a role in sexual development of vertebrates.

234 R3/R3) mice show no adverse effects in their sexual development or fertility or in the attenuation of

235 rner syndromes) and people with disorders of sexual development reflect the diversity in sex-based bi

236 ex determination, most cases of disorders of sexual development remain unexplained.

237 Elimination of sexual development rescues both growth and developmental

238 se repression of both fbp1 transcription and sexual development, resembling cells lacking either the

239 l germination and uncontrolled activation of sexual development resulting in a small colony covered b

240 Transfectants lacking Pfg27 abort early in sexual development, resulting in vacuolated, highly disa

241 f strains during growth and both asexual and sexual development revealed phenotypes for 43% of the de

242 sensitive to osmotic stress and impaired for sexual development, showing that fission yeast uses a co

243 o profound defects in growth and asexual and sexual development, similar to those observed for a muta

244 ge development, whereas six are required for sexual development/sporogony in mosquitoes.

245 ite prevalence declines, affects the optimal sexual development strategy: Within-host competition in

246 certain conditions that impact olfaction and sexual development, such as Kallmann syndrome, may be in

247 havior are similar to those controlling body sexual development, suggesting biological advantages of

248 uption of the pathway causes disordered male sexual development, suggesting it plays an essential rol

249 lso caused faster transition from asexual to sexual development, supporting the involvement of sphing

250 act that environmental conditions inhibiting sexual development suppress growth defects of the Delta

251 Exogenous cAMP, a key regulator for sexual development, suppressed conjugation and sporulati

252 factors Sxi1alpha and Sxi2a are required for sexual development that produces infectious spores, but

253 ignaling molecule that modulates asexual and sexual development, the formation of infection body appr

254 iated with earlier, and others with delayed, sexual development; these genetic results mimic the cont

255 e overrepresented among genes induced during sexual development; they were particularly enriched in a

256 ance on companion animals to study T. gondii sexual development, this work will allow the T. gondii f

257 expression in nascent merozoites to initiate sexual development through a hitherto unknown mechanism.

258 e) or off (male) state, Sxl controls somatic sexual development through control of downstream effecto

259 all proportion of these parasites commits to sexual development to mediate mosquito transmission.

260 t work on the signalling pathways regulating sexual development, together with transcriptomic and pro

261 GprH also represses sexual development under conditions favouring sexual fru

262 first genome-wide significant locus for male sexual development upstream of myocardin-like 2 (MKL2) (

263 lus) to male urinary scent accelerates their sexual development (Vandenbergh effect).

264 he molecular pathways they employ to control sexual development vary considerably.

265 ete fungus, Schizophyllum commune, regulates sexual development via proteins Y and Z.

266 le of the A alpha genes in the regulation of sexual development, we transformed various A alpha Y and

267 ting-type genes are the master regulators of sexual development; we are just beginning our search for

268 bias is less pronounced in cells undergoing sexual development, when many pombe-specific genes becom

269 , but little is known about how dsx controls sexual development, whether DSX(F) and DSX(M) bind diffe

270 Androgens are important for male sexual development, which depend on the cognate receptor

271 ated signalling cascade negatively regulates sexual development, which is required for proper prolife

272 stage making it an ideal model for studying sexual development, which is sorely lacking in the group

273 onditions, the An-PHO80 cyclin also promotes sexual development while having a negative effect on ase

274 ves the way for future studies on Toxoplasma sexual development without the need for cat infections a