ライフサイエンスコーパス: sexually dimorphic

1 mmune responses in neuropathic pain could be sexually dimorphic.

2 lating energy and glucose homeostasis and is sexually dimorphic.

3 wild-caught lines of D. tenebrosa and is not sexually dimorphic.

4 males and decreased in males, again becoming sexually dimorphic.

5 y receptor expression, whose abundances were sexually dimorphic.

6 lying cocaine environmental associations are sexually dimorphic.

7 vity in the AVPV/PeN, but not in the Arc, is sexually dimorphic.

8 hat metabolic regulation of rWAT and iWAT is sexually dimorphic.

9 echanisms underlying ischemic cell death are sexually dimorphic.

10 nd regionally restricted, and in many cases, sexually dimorphic.

11 tissue-specific manner with some also being sexually dimorphic.

12 subesophageal zone (SEZ), some of which are sexually dimorphic.

13 relative abundance of fibrogenic cells were sexually dimorphic.

14 approximately one-third of all signals to be sexually dimorphic.

15 ique complements of genes, may contribute to sexually dimorphic AAA pathology.

16 re the principal mechanisms of sculpting the sexually dimorphic abdomen of Drosophila.

17 ary tract (LUT) and micturition reflexes are sexually dimorphic across mammals.

18 (Wg) morphogen underlies the development of sexually dimorphic adult segment number in Drosophila.

19 Here, we identify a population of sexually dimorphic aIPg neurons in the adult Drosophila

20 velopmental changes in CV emerge through the sexually dimorphic and age-dependent interaction of chan

21 Since ELS effects are often sexually dimorphic and amygdala processes exhibit hemisp

22 However, this circuit is sexually dimorphic and changes across neurodevelopment.

23 rohabitats, and that such adaptations may be sexually dimorphic and dependent on local environments.

24 ose that cis-regulatory changes in pdm3 form sexually dimorphic and monomorphic alleles that segregat

25 s, ebony, we observe convergent evolution of sexually dimorphic and monomorphic expression through ci

26 However, it is unknown how this mosaic of sexually dimorphic and monomorphic organs arises.

27 Thus, the mosaic of sexually dimorphic and monomorphic organs depends on mod

28 gy expenditure, and glucose homeostasis in a sexually dimorphic and partially sex steroid-independent

29 nses to preferred-direction theta motion are sexually dimorphic and particularly robust along the vis

30 of ELS exposure on BLA synaptic function are sexually dimorphic and possibly recruiting different mec

31 ) had local gray matter volume that was both sexually dimorphic and predicted in a congruent directio

32 The extent to which nervous systems are sexually dimorphic and the cellular and molecular mechan

33 The density of dendritic spines is sexually dimorphic and variable throughout the female es

34 stem of adult animals, in a region-specific, sexually-dimorphic and experience-dependent manner.

35 The oscillation patterns induced by SST were sexually dimorphic, and could be explained by differenti

36 n regions, including the amygdala, are often sexually dimorphic, and have been reproduced using the r

37 his hierarchy is bilaterally symmetrical and sexually dimorphic, and it was used to create a structur

38 tory correlates of intelligence in sleep are sexually dimorphic, and they are not restricted to eithe

39 ereas families of probands affected with non-sexually dimorphic autoimmune diseases exhibit unbiased

40 tion of a neurotrophic factor signal directs sexually dimorphic axonal growth and maintenance, result

41 Our study shows sexually dimorphic behavior during migration, in additio

42 ental disease processes, and a substrate for sexually dimorphic behavior in adolescence.

43 y dimorphic morphology and the potential for sexually dimorphic behavior in Drosophila are regulated

44 cohesive internal states that correspond to sexually dimorphic behavior is poorly understood.

45 nter-male aggressive behavior is a prominent sexually dimorphic behavior.

46 criptomes, cells, and circuits in regulating sexually dimorphic behavior.

47 digit (2D:4D) ratio correlates with numerous sexually dimorphic behavioral and physiological conditio

48 xperimental paradigm for the study of innate sexually dimorphic behaviors [1, 2].

49 Sexually dimorphic behaviors are a consequence of a sexu

50 dings demonstrate that various components of sexually dimorphic behaviors are governed by separable g

51 Understanding how these sexually dimorphic behaviors are regulated at the level

52 derstanding of the neural circuit control of sexually dimorphic behaviors from several perspectives,

53 estrogen and testosterone are essential for sexually dimorphic behaviors in vertebrates.

54 imorphic neurons in particular, can generate sexually dimorphic behaviors, and how molecular mechanis

55 ex hormones control the entire repertoire of sexually dimorphic behaviors, including those commonly t

56 Sexually dimorphic behaviors, qualitative or quantitativ

57 ide insight into how neural circuits control sexually dimorphic behaviors.

58 iety-like behavior, leading to disruption of sexually dimorphic behaviors.

59 ner, within neural systems known to underpin sexually dimorphic behaviors.

60 Thus, the sexually dimorphic behaviour of the PAR is in part a res

61 he sexes and the more traditional pattern of sexually dimorphic behaviour.

62 osome and mitochondrial DNA haplogroups with sexually-dimorphic behavioural and psychiatric traits.

63 Sexually dimorphic behaviours require underlying differe

64 responsive to cVA, a pheromone that elicits sexually dimorphic behaviours.

65 ect of the medial amygdala (MePD) in rats is sexually dimorphic, being larger and containing more and

66 e, in adult rats and humans, LSt neurons are sexually dimorphic, being more numerous in males.

67 ession levels of the genes they regulate are sexually dimorphic between the parental D. simulans and

68 Sexually dimorphic bone structure emerges largely during

69 fying rare variants in genes associated with sexually dimorphic brain development and exploring how t

70 ed in estrogen signaling pathways related to sexually dimorphic brain development and their relations

71 l to understand early events contributing to sexually dimorphic brain development, we identified nove

72 ibed estrogen receptor activated pathways of sexually dimorphic brain development.

73 The amygdala is a sexually dimorphic brain region critical for the regulat

74 rganizational gonadal hormones establish the sexually dimorphic brain, confirmed dysmasculinization i

75 viously unappreciated role in organizing the sexually dimorphic brain.

76 Most animals are sexually dimorphic, but different taxa have different se

77 In each brain area, CRF receptor binding was sexually dimorphic, but no two areas were alike in the w

78 Physiology and metabolism are often sexually dimorphic, but the underlying mechanisms remain

79 Thus, sexually dimorphic cAMP signaling might render males and

80 at oviraptorosaurs would be found to display sexually dimorphic caudal osteology.

81 -determining genes, but the genetic basis of sexually dimorphic cell differentiation is rarely unders

82 and (ii) each structure harbors hotspots of sexually dimorphic change over adolescence--with relevan

83 However, despite these profound, sexually dimorphic changes in markers of DA neurotransmi

84 oexcitatory actions of insulin and implicate sexually dimorphic changes in NPY inhibition of SNA in t

85 This sexually dimorphic circuit composed of three neuronal cl

86 as a distinct function in the elaboration of sexually dimorphic circuitry and behavior.

87 gion of the male nervous system contains the sexually dimorphic circuits for mating.

88 criptomic types (T-types), including several sexually dimorphic clusters, the majority of which were

89 rotection from early-onset alopecia, another sexually dimorphic condition.

90 lation of pain, with a focus on the PAG as a sexually dimorphic core of descending opioid-induced inh

91 tion and gonadal hormone regulation of these sexually dimorphic CRFR1 cells using immunohistochemical

92 Those genes include sexually dimorphic cytochrome P 450 Cyp2d9, glutathione

93 essed genes downstream of dsx that drive the sexually dimorphic development of the genitalia, we perf

94 hese neurotransmitters may not contribute to sexually dimorphic development of the song system, they

95 To determine the mechanism underlying this sexually dimorphic difference in clinical outcome, we le

96 yed as experimental platforms to investigate sexually dimorphic differences in learning/memory, visua

97 We found that the timing of sexually dimorphic differentiation of postmitotic, sex-s

98 ogen, the developmental mechanism underlying sexually dimorphic digit development remains unknown.

99 In addition, we identified sexually dimorphic dsx circuitry within the abdominal ga

100 The sexually dimorphic effect of BPA on Kcc2 expression was

101 ng, implicating metabolic mechanisms in this sexually dimorphic effect.

102 s often been overlooked, despite evidence of sexually dimorphic effects in some biological studies.

103 These sexually dimorphic effects of COMT on inhibitory brain a

104 These studies reveal previously unrecognized sexually dimorphic effects of FOXA2 and uterine glands o

105 LPS-induced activation and contribute to the sexually dimorphic effects of morphine in the rat.SIGNIF

106 uctal gray (PAG) microglia contribute to the sexually dimorphic effects of morphine.

107 is known about the mechanism underlying the sexually dimorphic effects of stress.

108 a common genetic variation reported to have sexually dimorphic effects on cognition and temperament

109 We also observed evidence of sexually dimorphic effects; BPA concentrations were asso

110 a likely direct dsx target, to elucidate how sexually dimorphic expression and its evolution are brou

111 Many genes have evolved sexually dimorphic expression as a consequence of diverg

112 The onset of this sexually dimorphic expression coincides with the onset o

113 volution, roles in male mating behavior, and sexually dimorphic expression in neurons of the male for

114 ressiveness of Drosophila males reflects the sexually dimorphic expression of a neuropeptide that con

115 The results demonstrate that the sexually dimorphic expression of CYP2C11 is irreversibly

116 m mothers exposed to HFD feeding exhibited a sexually dimorphic expression of DA-related phenotypes,

117 Gonadal sex reversal did not alter the sexually dimorphic expression of either sex-linked or IF

118 Sexually dimorphic expression of ERbeta in the MePD was

119 ound that Dmrt1 has a temperature-dependent, sexually dimorphic expression pattern, preceding gonadal

120 Due to sexually dimorphic expression patterns, female mice have

121 flox) revealed that 36 genes required GR for sexually dimorphic expression, whereas 24 genes became s

122 pressive episodes) and biology (genetics and sexually dimorphic factors).

123 ostpubertally pattern cells and tissues in a sexually dimorphic fashion, sex differences are caused b

124 s the intrinsic properties of these cells in sexually dimorphic fashion.

125 rt females into males with all male-specific sexually dimorphic features and male-like gene expressio

126 Rapid changes in such sexually dimorphic features are likely a result of chang

127 Many somatic sexually dimorphic features of Drosophila melanogaster a

128 We studied whether sexually dimorphic features related to sexual hormones d

129 /MAB-3/DMRT1) are responsible for generating sexually dimorphic features.

130 Our findings help explain sexually dimorphic fin regeneration in zebrafish and hav

131 primate model of AT, we tested whether this sexually dimorphic finding is evolutionarily conserved a

132 milies of the guppy (Poecilia reticulata), a sexually dimorphic fish with SA polymorphisms for male c

133 MS1 neurons do not express the sexually dimorphic FRUITLESS (FRU) transcription factor,

134 cases suggest involvement of target genes in sexually dimorphic functions.

135 eases and is promoted by approximately eight sexually dimorphic, GABAergic interneurons of the male a

136 cellular species was reprogrammed to control sexually dimorphic gamete development in a multicellular

137 Here we characterized sexually dimorphic gene expression in multiple data sets

138 First, we defined region-specific and sexually dimorphic gene expression in the mouse bed nucl

139 We have identified numerous sexually dimorphic gene expression patterns in the adult

140 riptomic map of the proximal tubule revealed sexually dimorphic gene expression that may reflect sex-

141 The liver is characterized by sexually dimorphic gene expression translating into sex-

142 ironmental and other non-developmental cues, sexually dimorphic gene regulation, and non-endogenous (

143 analysis in CD4+ T cells showed that the top sexually dimorphic gene was Kdm6a, a histone demethylase

144 ach diet provided a distinctive signature of sexually dimorphic genes, with expression generally high

145 ates, eventually leading to the evolution of sexually dimorphic genetic architectures for male and fe

146 f these data for the identification of novel sexually dimorphic genomic enhancers and novel downstrea

147 monstrate for the first time the presence of sexually dimorphic glomeruli within a distinct macroglom

148 ergic neurotransmitter identity, including a sexually dimorphic glutamatergic to cholinergic neurotra

149 This study reveals another aspect of sexually dimorphic gonad development, establishes a prec

150 How sexually dimorphic gonads are generated is a fundamental

151 During infancy, there is a sexually dimorphic growth response to the mode of infant

152 Due to sexually dimorphic growth, southern flounder fisheries a

153 t a controlled breeding experiment using the sexually dimorphic Gulf pipefish, Syngnathus scovelli, t

154 , is expressed at highest levels in a single sexually dimorphic gustatory neuron of most taste hairs

155 Here, we discover that sexually dimorphic HCC is completely reversed in Foxa1-

156 ARC ERalpha and Kiss1 levels were abundant, sexually dimorphic (higher in females), and, respectivel

157 al portion of the medial amygdala (MePD) are sexually dimorphic in adult rats: males have more astroc

158 e results demonstrate that PAG microglia are sexually dimorphic in both basal and LPS-induced activat

159 Our results were sexually dimorphic in both cohorts.

160 Hepatocellular carcinoma (HCC) is sexually dimorphic in both rodents and humans, with sign

161 imorphic expression, whereas 24 genes became sexually dimorphic in LGRKO.

162 (P < 0.001) overlapped with areas that were sexually dimorphic in neurotypical controls, in both gre

163 unction in circuits for sexual behaviour are sexually dimorphic in structure and connectivity.

164 Many psychiatric traits are sexually dimorphic in terms of prevalence, age of onset,

165 of both amygdala and hypothalamus were also sexually dimorphic in the direction of Male > Female, bu

166 its that have been found to be significantly sexually dimorphic in the pure species were either not d

167 ort that the number of astrocytes is already sexually dimorphic in the right MePD of juvenile 25-day-

168 unction might provide an explanation for the sexually-dimorphic increase in longevity generally obser

169 otion that species-poor islands harbour more sexually dimorphic individuals or species.

170 Rheumatoid arthritis (RA) is a sexually dimorphic inflammatory autoimmune disease with

171 To determine the contribution of GR to sexually dimorphic inflammatory genes we performed nanos

172 Of these baseline sexually dimorphic inflammatory genes, 82% was expressed

173 We thus identify a sexually dimorphic IS susceptibility locus, and propose

174 uropeptide F (NPF) in two neurons within the sexually dimorphic LNd region and its receptor NPFR1 in

175 minantly have dendritic arborizations in the sexually dimorphic macroglomerular complex (MGC) and sen

176 Sexually dimorphic mammalian tissues, including sexual o

177 pregnancy with infant neurodevelopment in a sexually dimorphic manner are poorly understood.

178 s of the same species can differentiate in a sexually dimorphic manner is not well understood.

179 particular, alters ethanol sensitivity in a sexually dimorphic manner, since neuronal activation enh

180 Interestingly, BPA exerted its effect in a sexually dimorphic manner, with a more accentuated effec

181 flying adults use an enlarged opsin set in a sexually dimorphic manner, with some expressed only in m

182 approximately 600 genes were expressed in a sexually dimorphic manner.

183 insights into how neurons are specified in a sexually dimorphic manner.

184 amygdala architecture and connectivity in a sexually dimorphic manner.

185 Sexually dimorphic mate selection rituals are likely con

186 Evidence for sexually dimorphic maturational coupling was found withi

187 eraction with fru neurons, many of which are sexually dimorphic, may account for the sex-specific eff

188 terogeneity, including efforts to understand sexually dimorphic mechanisms, the longitudinal dynamics

189 ion of oogenesis and spermatogenesis through sexually dimorphic mechanisms: it is essential in female

190 The sexually dimorphic medial preoptic nucleus (POM) in Japa

191 isolated to the gene doublesex, we show that sexually dimorphic mimicry and female-limited polymorphi

192 The development of sexually dimorphic morphology and the potential for sexu

193 ME analysis shows high frequency and unique, sexually dimorphic motifs in the TCR hypervariable regio

194 otein connexin-36 is widely expressed in the sexually dimorphic motoneurons of the L6 segment, sugges

195 diate copulation in Drosophila, and define a sexually dimorphic motor circuit in the male abdominal g

196 at contains limb-innervating motoneurons and sexually dimorphic motor nuclei.

197 SKG mice represent an authentic sexually dimorphic mouse model of both the joint and lun

198 The mating locus (MT) of the sexually dimorphic multicellular green alga Volvox carte

199 ic profiles from human livers emphasized the sexually dimorphic nature of NASH and its link with fibr

200 istochemistry (ISHH) to map the temporal and sexually dimorphic neonatal mRNA expression profiles of

201 A sexually dimorphic network of brain regions controls lea

202 Here, we demonstrate sexually dimorphic neural coding of odorants by olfactor

203 termination pathway to control the timing of sexually dimorphic neural development in C. elegans.

204 uppressed by prior exposure to females via a sexually dimorphic neural mechanism.

205 ts suggest that the familial transmission of sexually dimorphic neurocognitive domains, in which a pa

206 behavior revealed the involvement of another sexually dimorphic neuron, pC1d, and implicated aIPg and

207 l behavior by controlling the development of sexually dimorphic neuronal circuitry.

208 escribe here a novel mechanism that promotes sexually dimorphic neuronal function and synaptic connec

209 veal the functions of a molecularly defined, sexually dimorphic neuronal population in the brain.

210 differences, but the function of individual sexually dimorphic neuronal populations is poorly unders

211 Moreover, we show that sexually dimorphic neurons can control distinct sex-typi

212 ncluding how neural circuits in general, and sexually dimorphic neurons in particular, can generate s

213 This work extends our understanding of the sexually dimorphic niche architecture, but also demonstr

214 ic area of the adult sheep contains an ovine sexually dimorphic nucleus (oSDN) that is larger and has

215 The sexually dimorphic nucleus of the preoptic area (SDN-POA

216 g sexual differentiation of the hypothalamic sexually dimorphic nucleus.

217 We identified a small subset of sexually dimorphic OA/dsx(+) neurons (approximately nine

218 ia x ananassa subsp. cuneifolia) between two sexually dimorphic octoploid strawberry species (Fragari

219 s has been made in identifying components of sexually dimorphic olfactory circuits in both Drosophila

220 s high throughout the amygdala at birth, but sexually dimorphic only in the AHi.

221 eural song system in zebra finches is highly sexually dimorphic; only males sing and the brain region

222 brillary acidic protein immunoreactivity are sexually dimorphic or affected by gonadal hormones in th

223 s are responsible for dsx expression in each sexually dimorphic organ.

224 How neural circuits associated with sexually dimorphic organs are differentially assembled d

225 thalamus and two hypothalamic nuclei display sexually dimorphic OTR expression.

226 courtship ritual triggered by activation of sexually dimorphic P1 interneurons.

227 ed pattern-recognition receptors as the most sexually dimorphic pathway.

228 vely, that they interact with characteristic sexually dimorphic pathways.

229 Here, we report a sexually dimorphic pattern of mouse mammary gland sensor

230 We show that eve has a sexually dimorphic pattern, suggesting an interaction wi

231 al tubulogenesis, prepuce morphogenesis, and sexually dimorphic patterning of the lower urethra are c

232 Furthermore, auto-editing exhibits sexually dimorphic patterns of spatial regulation and ca

233 tide and two receptors that are expressed in sexually dimorphic patterns.

234 homeostatic mechanisms to generate a robust sexually dimorphic phenotype in the main olfactory epith

235 ession in Drosophila are thought to underlie sexually dimorphic phenotypes and have been shown to pos

236 les may favor their role in the evolution of sexually dimorphic phenotypes, and that trans-regulatory

237 function and behavior, especially regarding sexually dimorphic phenotypes.

238 functional evolution of sex chromosomes and sexually dimorphic phenotypes.

239 del, we show that loss of FAM19A1 results in sexually dimorphic phenotypes.

240 pecific KAP1 knockout (KO) led to strikingly sexually dimorphic phenotypic disturbances, including ma

241 ion-manipulated mate choice trials, we found sexually dimorphic polarized reflectance and polarizatio

242 on, stem cells may partially account for the sexually dimorphic postweaning development of the SDN-PO

243 ary effect of gonadal steroids in the highly sexually dimorphic preoptic area (POA) is to reduce acti

244 D risk genes, but rather naturally occurring sexually dimorphic processes, potentially including neur

245 ars highlight the breadth and persistence of sexually dimorphic programming effects in humans.

246 ion of the RA metabolizing enzymes indicates sexually dimorphic RA levels.

247 showed unusual multi-body-part responses and sexually dimorphic receptive fields.

248 fraction of the genome shows some degree of sexually dimorphic recombination, the vast majority of h

249 nucleus of the stria terminalis (BNST) is a sexually dimorphic region that critically regulates nega

250 Thus, we resolved sexually dimorphic regulation of Irx3 and Irx5 via epige

251 This research reveals a sexually dimorphic regulation of synaptic plasticity in

252 Co-evolution of sexually dimorphic reinforcement systems can explain the

253 y the vasopressin system, characterized by a sexually dimorphic response and involved in the regulati

254 We find a sexually dimorphic response; intrauterine growth restric

255 of Alk may be one mechanism responsible for sexually dimorphic responses to cocaine.

256 Finally, the sexually dimorphic responses to dural CGRP were not spec

257 recent studies describe mechanisms by which sexually dimorphic responses to pheromones in the nemato

258 ifying the top 10 diseases showed strikingly sexually dimorphic risks.

259 Here, we uncover a sexually dimorphic role of the medial amygdala (MeA) in

260 We investigated, in a large sexually dimorphic seabird which predominantly uses dyna

261 ogenic effector T cells in the glands with a sexually dimorphic selection bias of TCR repertoires.

262 egree of stimulus selectivity and a striking sexually dimorphic sensory representation that are not o

263 Sexually dimorphic sensory systems are common in Hymenop

264 rain-derived neurotrophic factor (BDNF), and sexually dimorphic sequestering of BDNF by the truncated

265 echanisms underlying normal and pathological sexually dimorphic social behaviours.

266 in the development and maintenance of costly sexually dimorphic somatic and behavioral traits.

267 Unlike previous examples of sexually dimorphic somatic stem cell activity, the sex d

268 Thus, the LSt group is sexually dimorphic soon after birth.

269 Floral rewards are known to vary between sexually dimorphic species and to a lesser extent betwee

270 nary origins of gamete-specific functions in sexually dimorphic species.

271 These sexually dimorphic structures evolve rapidly and derive

272 Its similarity to a cock's comb and other sexually dimorphic structures of birds suggests that pot

273 ons describe the developmental patterning of sexually dimorphic structures that have been critical to

274 ted final instar larvae showed male-specific sexually dimorphic structures.

275 g appendage, the stylet, and discovered that sexually dimorphic stylet neurons taste blood.

276 re cells in the female brain in 10 out of 11 sexually dimorphic subcortical areas, in contrast to the

277 tively predicted gray matter volume of a non-sexually dimorphic subregion of the amygdala.

278 of atherosclerosis and may contribute to the sexually dimorphic susceptibility to atherosclerosis by

279 ale nervous systems reveals the existence of sexually dimorphic synaptic connections between neurons

280 es of Fmo-2 transcription in the midgut from sexually dimorphic to sexually monomorphic in some speci

281 Left-handedness is a costly, sexually dimorphic trait found at low frequencies in all

282 action of the variance in tail morphology (a sexually dimorphic trait), and two QTLs contained no gen

283 ing relationships between mating success and sexually dimorphic traits (e.g., ornaments), individual

284 In Drosophila melanogaster, most sexually dimorphic traits are controlled by sex-specific

285 y of ecology and the co-option of ancestral, sexually dimorphic traits for sib-rearing.

286 oduction (including, increased expression of sexually dimorphic traits in males).

287 manipulate the behavior of pollinators using sexually dimorphic traits in the dioecious tree Eurya ja

288 , whereas computer simulation suggested that sexually dimorphic traits would evolve if pollinators ch

289 is mostly limited to cells that give rise to sexually dimorphic traits.

290 Gender-appropriate production of the sexually dimorphic transcription factors doublesex and f

291 Sexually dimorphic transcriptome is an uncharted territo

292 in the brain are often taken as support of a sexually dimorphic view of human brains ("female brain"

293 t early-life play experience is likely to be sexually dimorphic when males and females show pronounce

294 undergo developmental changes, and is highly sexually dimorphic, which likely has significant functio

295 skin mucus metabolome showed it to be highly sexually dimorphic with 72 of the detected metabolites s

296 These effects were sexually dimorphic with HR complexity being more strongl

297 Depression is sexually dimorphic with males and females exhibiting dif

298 fic neuronal populations in this nucleus are sexually dimorphic, with females possessing more kisspep

299 We found that MSN activity presentation is sexually dimorphic, with MSN females showing higher in-c

300 human germline development must consider the sexually dimorphic X-chromosome dosage compensation mech