ライフサイエンスコーパス: sheep

1 f four animal species: horse, pork, beef and sheep.

2 estation, term = 145 d), neonatal, and adult sheep.

3 n both healthy and diseased feet of diseased sheep.

4 trains from both clades are found in bighorn sheep.

5 lly relevant cardiopulmonary-bypass model in sheep.

6 uperior marginal defect in five of six (83%) sheep.

7 to corral and contain small herds of virtual sheep.

8 d in human bronchial epithelial cells and in sheep.

9 arcinoma (OPA), a neoplastic lung disease of sheep.

10 r defect of physiologically relevant size in sheep.

11 facial nerve using cadaver and anesthetized sheep.

12 fflicts animals, including dogs, horses, and sheep.

13 rrhaphy under surgical microscopy in cadaver sheep.

14 of marine lipids than DPA both in cattle and sheep.

15 ial communities and ARGs in hooves from four sheep.

16 1-12) and IUGR (n = 12) late gestation fetal sheep.

17 saline-infused control segments in the same sheep.

18 ease that reduces health and productivity of sheep.

19 fetal cardiomyocyte contractile function in sheep.

20 x, medulla, and within a bladder catheter in sheep.

21 conceived sheep, and our healthy aged cloned sheep.

22 ies and parasite-specific IgG in female Soay sheep.

23 ied as fat-tail, thin-tail and fat-rump hair sheep.

24 acavirus that is carried asymptomatically by sheep.

25 colon, a rat esophagus, and small airways in sheep.

26 Scrapie is a prion (PrP(Sc)) disease of sheep.

27 rom presymptomatic HD transgenic and control sheep.

28 ased significantly in HD compared to control sheep.

29 ) signaling in osteocytes was not studied in sheep.

30 i-MAP antibody responses in paratuberculosis sheep.

31 phalography (EEG) response to ketamine of 12 sheep.

32 gital swabs from eight, preferably diseased, sheep.

33 in the process of short-term intake rate of sheep.

34 01) and short-term intake rate (P = 0.03) of sheep.

35 the top five globally important diseases of sheep.

36 g strategies for genetic improvement in meat sheep.

37 using data from a long-term study of bighorn sheep.

38 tested in in vitro phantom models and in 15 sheep.

39 aining osteochondral defects in experimental sheep.

40 e implanted into 8 female adult English Mule sheep.

41 ZOL sheep (2/6) showed inflammation and necrotic bone at man

42 83 bp), buffalo (363 bp), goat (396 bp), and sheep (477 bp).

43 In 12 sheep, 8 weeks of right atrial and right ventricular fre

44 s while, for species discrimination (cow vs. sheep) a percentage of 100% was obtained.

45 stic ruminants (cattle, buffaloes, goats and sheep), a revised estimation of yearly enteric CH(4) emi

46 insights into the pathobiology of C. jejuni sheep abortion clone and strongly suggest that CjNC110 p

47 gets or interactive partners of CjNC110 in a sheep abortion clone of C. jejuni These data were then u

48 C. jejuni IA3902 (representative of the sheep abortion clone) is genetically similar to C. jejun

49 n fecal DNA samples from thirty-nine bighorn sheep across seven loosely connected populations in the

50 the history of migration and pastoralism of sheep across the Old World, which was associated with di

51 included in vaccination programs to protect sheep adequately.

52 RDS and ECMO.Methods: ARDS was induced in 14 sheep, after which they were established on venovenous E

53 n ELISA was used to screen 977 cattle, 1,549 sheep and 523 goats and information on potential risk fa

54 A total of 8 normal sheep and 8 sheep with pacing-induced HF received increm

55 sed retroviral insertions in 80 modern Kihnu sheep and 83 ancient sheep from the Bronze Age to Modern

56 survey design, was 42.9% in cattle, 28.0% in sheep and 9.3% in goats, showing a high degree of farm-l

57 ide insights into the demographic history of sheep and a valuable genomic resource for future genetic

58 be important for cross-species transmission, sheep and cattle continue to be important for the transm

59 valuated in ELISA format using antisera from sheep and cattle experimentally infected with two geneti

60 ection) and with 97% and 100% specificity in sheep and cattle, respectively.

61 animals of commercial significance, such as sheep and cattle.

62 ative (unfixed), hydrated Achilles tendon of sheep and chickens.

63 d-type RVFV strains and sera from indigenous sheep and goat populations exposed to natural RVFV field

64 ttle, horse, and camel) and small livestock (sheep and goat).

65 for detection of three species, namely cow, sheep and goat, while as low as 1.6 fmol for cow and goa

66 hile cattle were four times as productive as sheep and goats regardless of animal output type.

67 terrestrial livestock (in particular cattle, sheep and goats), which is due largely to the absence of

68 d devastating viral disease affecting mainly sheep and goats, but also a large number of wild species

69 ence levels of 26.1% and 54.3% in indigenous sheep and goats, respectively, in The Gambia.

70 oexisting domestic ungulate species: cattle, sheep and horses.

71 reversible inhibition of RyR2 channels from sheep and human failing hearts.

72 Sheep and humans share similar precocial developmental m

73 Given the similarities between pregnancy in sheep and humans, we studied sheep to examine the impact

74 servoir, while the few spillovers to bighorn sheep and mountain goats can persist for extended period

75 given the high strain diversity in domestic sheep and need for more comprehensive pathogen surveilla

76 ies and improved genome-assisted breeding of sheep and other domestic animals.

77 Zooarchaeological remains of sheep and pig with minimal taphonomic modifications were

78 four different paternal lineages of domestic sheep and resolved, at the global level, their paternal

79 ng dryland stress adaptation in the fat-tail sheep and showcase the indigenous stocks as appropriate

80 rallel lymphatic vessels in the hind limb of sheep and the evaluation of structural and functional ch

81 d the first expansion of early domestic hair sheep and the later expansion of fat-tailed sheep occurr

82 ood-cerebrospinal fluid barrier (B-CSF-B) of sheep and to profile these compounds in sheep biofluids

83 the growth phases of 4469 Scottish Blackface sheep and weather variables during the same period to de

84 r fetus is a venereal pathogen of cattle and sheep, and an opportunistic human pathogen.

85 sed briefly after high-dose PDE9-I in normal sheep, and fell following the top dose in HF.

86 s in milk samples of different animals (cow, sheep, and goat) and type (colostrum, raw, and pasteuriz

87 unas indicate that herders relied on cattle, sheep, and goats and some hunting, but direct informatio

88 ds for meat and milk production from cattle, sheep, and goats by sorting pastures into climate bins d

89 of mouse, rat, chimpanzee, dog, horse, goat, sheep, and human Mxra8 enables alphavirus infection in c

90 e in domestic sheep, domestic goats, bighorn sheep, and mountain goats across the western United Stat

91 ilar to that observed in naturally conceived sheep, and our healthy aged cloned sheep.

92 Chickens, sheep, and rabbits use nontemplated point mutations and

93 form a distinct clade from those in domestic sheep, and strains from both clades are found in bighorn

94 t was surgically created and stabilized in a sheep animal model.

95 n, sprouting was assessed by the chicken and sheep aortic ring assay, and vascular pattern formation

96 ing tyrosine residues, Tyr-23 and Tyr-149 in sheep AQP0, to the corresponding residues in the high-pe

97 These data suggest domestic sheep are a reservoir, while the few spillovers to bigho

98 African indigenous sheep are classified as fat-tail, thin-tail and fat-rump

99 at can identify 80% of the presymptomatic HD sheep as transgenic, with 90% confidence.

100 t atrial fibrillation (n=20), (2) tachypaced sheep atrial fibrillation (n=5), (3) rat atrial fibrilla

101 uch information is needed to improve bighorn sheep augmentations and can be applied to augmentations

102 pancreatic islets isolated from intact fetal sheep, beta cell proliferation in vitro was reduced by T

103 ) of sheep and to profile these compounds in sheep biofluids after chokeberry intraruminal administra

104 We demonstrate that in vehicle-treated sheep, bleomycin-infused lung segments had significantly

105 Colonies from tryptic soy agar with 5% sheep blood (blood agar) and MacConkey agar were tested,

106 roach Na(V) channels and was insecticidal to sheep blowflies.

107 s; 3) delineated 25 external and 28 internal sheep brain structures by segmenting both templates and

108 high-resolution 3D atlas of average in vivo sheep brains linked to a reference stereotaxic space.

109 stricts with higher densities of susceptible sheep breeds and buffalo.

110 losa cells similar to that are documented in sheep breeds carrying the FecB mutation.

111 n the BMPR-IB gene was identified in certain sheep breeds having high fecundity.

112 ith data from 330 individuals of 16 domestic sheep breeds.

113 art rate and plasma renin activity in intact sheep, but these responses were significantly attenuated

114 re the creation of pancreatogenesis-disabled sheep by oocyte microinjection of CRISPR/Cas9 targeting

115 of Lucilia cuprina, which is a major pest of sheep, by combining both lethal effectors in a single tr

116 hat suppression of MEIS1 expression in fetal sheep cardiomyocytes leads to a metabolic switch as foun

117 Further, we infer that Soay and Sarda sheep carry introgressed mouflon alleles involved in bit

118 isobaric chambers, chronically catheterized sheep carrying singletons underwent normoxia or hypoxia

119 ls, including camels, cattle, horses, goats, sheep, cats, rabbits, and pangolins, were able to suppor

120 arcinoma is a chronic respiratory disease of sheep caused by jaagsiekte sheep retrovirus (JSRV).

121 Here, we show that in sheep, CNTfs sewn across epicardial scar acutely improve

122 report detailing the health status of cloned sheep concluded that the animals had aged normally.

123 enetic diversity in mouflon than in domestic sheep, consistent with past bottlenecks in mouflon.

124 We found immature-like neurons in the whole sheep cortex and in large populations of DCX-expressing

125 Our analyses of St Kilda Soay sheep data thus concurs with our cross-study review that

126 Natural prion susceptible hosts such as sheep, deer and cattle are regularly exposed to gastroin

127 s after 8 months using 31 female merino land sheep divided into four groups: control, ovariectomy, ov

128 nary Association/ Kennel Club/ International Sheep Dog Society (BVA/KC/ISDS) eye scheme annually, and

129 cterium Mycoplasma ovipneumoniae in domestic sheep, domestic goats, bighorn sheep, and mountain goats

130 e also tested for hemolytic activity against sheep erythrocytes.

131 FH levels on a human HAP-1 cell line and on sheep erythrocytes.

132 In pregnant sheep, experimental models with a small, defective place

133 l tissue from a cohort of 5-y-old OVT73-line sheep expressing a human CAG-expansion HTT cDNA transgen

134 an important economic and welfare issue for sheep farmers and a valuable naturally occurring animal

135 OPA is a significant economic problem for sheep farmers in many countries and is a valuable animal

136 sistence of D. nodosus and F. necrophorum in sheep feet, mouths and faeces, and in soil.

137 Hypothyroidism in the sheep fetus resulted in an asymmetric pattern of organ g

138 inding has been replicated in normally grown sheep fetuses following a 7-day noradrenaline (norepinep

139 cell proliferation and mass were examined in sheep fetuses following removal of the thyroid gland in

140 ent synchronization method for G2/M phase of sheep fibroblasts, which was successfully applied to flo

141 that D. nodosus and F. necrophorum depend on sheep for persistence but use different strategies to pe

142 ions in 80 modern Kihnu sheep and 83 ancient sheep from the Bronze Age to Modern Period (850 BCE-1950

143 ealed two migratory episodes of domesticated sheep from the Middle East to Europe.

144 Why do distantly related mammals like sheep, giant pandas, and fur seals produce bleats that a

145 multiple animal species, such as dogs, pigs, sheep, goats, cattle and horses, have been substantially

146 some 5,500 years ago followed those of dogs, sheep, goats, cattle, and pigs by ~2,500-10,000 years.

147 total CLA content of milk samples from cows, sheep, goats, yaks, and llama retrieved from the collect

148 explored the short and long-term impacts of sheep grazing and/or hay cutting on arthropod foliage co

149 ndance and trophic level during manipulative sheep grazing are not well understood.

150 and trophic level in response to continuous sheep grazing in steppe grasslands.

151 Insect abundance decreased as sheep grazing intensities increased, with a significant

152 gs highlight the importance of more flexible sheep grazing management and will be useful for developi

153 te that continuous years of heavy- and over- sheep grazing should be eliminated.

154 ididae and Cicadellidae, were susceptible to sheep grazing, but Formicidae was tolerant.

155 We identified that the Kihnu sheep have preserved 'primitive', 'Nordic', and other 'a

156 Feeding experiments with sheep have shown negligible effects of dust-laden grass

157 s from 5 ex vivo Langendorff-perfused PersAF sheep hearts (sensitivity/specificity, 92.6/97.5%; accur

158 Isolated, Langendorff-perfused sheep hearts were optically mapped.

159 48.7 ug/g protein), followed by cattle, pig, sheep, horse, cat and deer: >75% was conjugated.

160 LMG-bovine serum albumin and rabbit anti-sheep IgG were immobilized on nitrocellulose membrane fo

161 eographically distinct genepools of fat-tail sheep in Africa that differ from the European genepool,

162 whether the recently discovered Kihnu native sheep in Estonia have historically been part of the firs

163 Consequently, 9 sheep in late gestation were anesthetized with isofluora

164 hogenic (T. ovis), amongst a cohort of naive sheep in Oman.

165 e (BT), caused by bluetongue virus (BTV), in sheep in southern India, where annual BT outbreaks const

166 1989 and 2008 from a wild population of Soay sheep in the St.

167 Here, we report the deep resequencing of 248 sheep including the wild ancestor (O. orientalis), landr

168 Hypothyroidism in fetal sheep induced by removal of the thyroid gland caused asy

169 ion, a high rate of mortality was seen among sheep infected with T. lestoquardi alone.

170 In conscious sheep, infusion of Escherichia coli decreased creatinine

171 Brains from adult and newborn sheep (injected with BrdU and analyzed at different surv

172 that growth retardation in hypothyroid fetal sheep is associated with reductions in pancreatic beta c

173 lambda(d), 4.6%/ms+/-1.5 [95% CI, 4.3-4.9]; sheep: lambda(f), 4.4%/ms [95% CI, 4.1-4.7], lambda(d),

174 ise in tri-iodo-l-thyronine (T(3) ) in fetal sheep leads to the inhibition of proliferation and promo

175 METHOD AND In 7 sheep, left ventricular endocardial and transmural mappi

176 rce of periostin and VCAM-1 was the inflamed sheep liver tissue.

177 (R151X) human mutation into the orthologous sheep locus.

178 ve quantification of buffalo meat mixed with sheep meat was done by quantitative label-free mass spec

179 ffalo meat spiked at a minimum 0.5% level in sheep meat with high confidence.

180 t mixes containing cattle, water buffalo and sheep meat.

181 nd, we performed long-read sequencing of the sheep microbiome and applied metaFlye to reconstruct 63

182 e validated this hypothesis in primary fetal sheep microglia cultures re-exposed to LPS in presence o

183 Cow, goat and sheep milk and yogurt were compared at designated timepo

184 mit were 1.43 and 4.77mg/ml respectively for sheep milk and, 2.25 and 7.5mg/ml respectively for goat

185 and preconcentration of SPI from aqueous and sheep milk samples, and an off-line MISPE method followe

186 atment for selective determination of SPI in sheep milk samples.

187 s of powdered milk, lyophilized Se-fortified sheep milk, and ERM-BD151 skimmed milk powder.

188 del (p = 6.0 x 10(-8)) and in the transgenic sheep model (p = 2.4 x 10(-88)).

189 Using a sheep model of advanced HF, we show that tadalafil treat

190 iously validated, now expanded pharmacologic sheep model of CF-like, inflammation-associated mucocili

191 in the beta-ENaC mouse model as well as the sheep model of CF.

192 This novel sheep model of CLN1 disease develops biochemical, gross

193 The current study reproduced the sheep model of osteoporosis to study the RANKL/OPG ratio

194 Using a sheep model of placental insufficiency and IUGR, we have

195 with omics methodology in a tenotomy-induced sheep model of rotator cuff disease, we tested whether m

196 We used a preterm fetal sheep model using both sexes in twin 0.65 gestation fetu

197 We used a preterm fetal sheep model using both sexes that reproduces the spectru

198 The sheep model was first used in the fields of animal repro

199 In a sheep model, administration of haptoglobin into the CSF

200 (Htt) gene knock-in model, a transgenic HTT sheep model, and humans.

201 validated and published nongenetic, CF-like sheep model, ewes inhaled CFTR(inh)172 and neutrophil el

202 d antiarrhythmic mechanisms of ranolazine in sheep models of paroxysmal (PxAF) and persistent AF (PsA

203 All of these observations in sheep models with placental insufficiency are consistent

204 ased and included woolly rhinoceros and wild sheep (mouflon), characteristic of a steppe environment.

205 and 135 +/- 1 days of gestational age (dGA) sheep (n = 7 per age; term ~145 dGA).

206 electrophysiology studies were performed in sheep (n=3).

207 for rotational stocking systems to optimize sheep nutrition on pastures.

208 urrent assemblies of the dog, CF 3.1 and the sheep, OA 3.1, genomes contain 264 and 598 FLIs, respect

209 sheep and the later expansion of fat-tailed sheep occurred ~11,800-9,000 years BP and ~5,300-1,700 y

210 ction area and with respect to species (cow, sheep) of two traditional cheese specialties, (salty and

211 s) collected from an unmanaged population of sheep on St Kilda, where individual age and parentage ar

212 rature, soil pH and ruminant animal species (sheep or cow) were significant factors influencing the E

213 iduals with lower age and who herded cattle, sheep or goats in the previous 12 months.

214 to circulate in most populations of bighorn sheep or mountain goats.

215 ation of immunoglobulins G (IgGs) from cows, sheeps, or goats.

216 nd suggesting that contemporary Kihnu native sheep originate from the first migratory episode.

217 f federally endangered Sierra Nevada bighorn sheep Ovis canadensis sierrae across three spatial scale

218 c changes underlying phenotypic variation in sheep (Ovis aries) may facilitate our efforts towards fu

219 In contrast, overexpression of Cdk5 in sheep (Ovis aries) only produces brown patches on a whit

220 ncing, sequences and genes annotation of the sheep (Ovis aries) Y chromosome are still absent.

221 rker for studying the demographic history of sheep (Ovis aries).

222 in a wild mammalian host, the desert bighorn sheep (Ovis canadensis nelsoni).

223 housing a wild population of desert bighorn sheep (Ovis canadensis) in the Chihuahuan desert of New

224 We monitored 127 female bighorn sheep (Ovis canadensis) released in three populations fr

225 Using an archival collection of Dall's sheep (Ovis dalli dalli), a capital breeder that depends

226 nsion and improved renal function in CKD-RDN sheep (p < 0.0001 for 2 and 5 months vs. pre-RDN).

227 lic guanosine monophosphate (cGMP) in normal sheep (p < 0.05) while concurrently reducing circulating

228 1.6 fmol for cow and goat, and 3.1 fmol for sheep PCR product were detected.

229 r's vagina (46%), ambient air (31%), and the sheep pen floor (12%).

230 In a sheep pharmacokinetic model, a ring containing two 1/4-l

231 ne traits in the individually monitored Soay sheep population of St Kilda, using genomic inbreeding c

232 winning across six age-sex classes in a Soay sheep population.

233 clustered and shared among proximate bighorn sheep populations, supporting pathogen establishment and

234 ource of infection for sympatric susceptible sheep populations.

235 Furthermore, Kihnu sheep possessed several 'novel' retrotypes that were abs

236 esistance to helminth parasites in wild Soay sheep predict overwinter mortality.

237 at S-type strains, which are more adapted in sheep, produce a unique lipid.

238 s similar in magnitude to the emissions from sheep production.

239 yogurt than milk, which was most evident for sheep products.

240 ymorphisms at positions 136, 154, and 171 of sheep PrP(C) or PrP(Sc).

241 Rocky Mountain bighorn sheep rams (Ovis canadensis canadensis) routinely conduc

242 In hypertensive CKD sheep, RDN reduced blood pressure and improved basal ren

243 Sheep received a prime-boost vaccination regime comprisi

244 Chymotrypsin was used to digest sheep recombinant PrP to identify a set of characteristi

245 and CIMVs-MSCs reduced serum levels of anti-sheep red blood cell antibody and have limited effects o

246 ique's applicability for biological samples, sheep red blood cells with various melittin peptide cont

247 EK293), animal cells (neuroblastoma N115 and sheep red blood cells), cancer cells (MCF-7, MDA-435 and

248 antigen-specific Ab after immunization with sheep red blood cells.

249 remaining 31.1% of reads were aligned to the sheep reference genome, including 13.57% reads to chromo

250 Jaagsiekte sheep retrovirus (JSRV) is the etiologic agent of ovine

251 ratory disease of sheep caused by jaagsiekte sheep retrovirus (JSRV).

252 rican and western Asia fat-tail and European sheep, reveal at least two phylogeographically distinct

253 (156 readings) with MHA supplemented with 5% sheep's blood (BMHA), using mecA PCR as the reference st

254 re made using non-standard heat treatment of sheep's milk at 60 degrees C/5min.

255 ee fatty acids (FFAs) during ripening of raw sheep's milk Tulum cheeses in goat's skin bag (GST) or p

256 Cow's, goat's and sheep's milks were tested.

257 akob disease; kuru; inherited prion disease; sheep scrapie; bovine spongiform encephalopathy; and chr

258 ELISA and the virus neutralization test for sheep sera (R (2) = 0.75; 95% confidence interval [CI] =

259 hat gave rise to Dolly, yet none of our aged sheep showed clinical signs of OA, and they had radiogra

260 the conservation program of the Kihnu Native Sheep Society.

261 The genetic structure of domestic sheep strains could not be explained by geography, where

262 ts for non-bovine ruminant species (goat and sheep), support for multiple assemblies per organism in

263 of the jejunum of human patients, cows, and sheep supported with a continuous-flow LVAD.

264 A sheep tendon injury model characterised by a natural his

265 d, we induced biventricular heart failure in sheep that developed tricuspid valve leakage.

266 We tested the hypothesis in sheep that maternal treatment with antioxidants protects

267 During CPB with cardiac surgery in sheep, the clinical applicability of Ir-CPI was investig

268 ural conditions.IMPORTANCE In goats, like in sheep, there are PRNP polymorphisms that are associated

269 usal gene for fat deposition in the tails of sheep through transcriptome, RT-PCR, qPCR, and Western b

270 l of bleomycin-induced pulmonary fibrosis in sheep to evaluate the remodelling of the pulmonary vascu

271 en pregnancy in sheep and humans, we studied sheep to examine the impact of MO on fetal cardiomyocyte

272 ividual-based data from a population of Soay sheep to examine variation in life-history strategies at

273 Sheep tracheal mucus velocity, an in vivo measure of muc

274 7079 reversed the effects of e-cig liquid on sheep tracheal mucus velocity.Conclusions: Our findings

275 lung segments were significantly reduced in sheep treated with the senicapoc, when compared to vehic

276 Sheep underwent RDN (control-RDN, n = 8; CKD-RDN, n = 7)

277 Near-term fetal sheep underwent surgical instrumentation and were studie

278 These results show that the adult sheep, unlike rodents, is largely endowed with non-newly

279 bility of regenerating large bone defects in sheep using 3D-printed customized calcium phosphate scaf

280 heart surgical implantation procedures in 10 sheep utilizing an antegrade transatrial access.

281 Groups of sheep vaccinated with a cocktail of six different vaccin

282 We explored the sheep variome and selection signatures.

283 or ARH/ARQ) scrapie-infected Rasa Aragonesa sheep was analyzed using this MRM method.

284 ncus was measured while a cadaver and living sheep was exposed to the sinusoidal acoustical excitatio

285 Systemic nicotine delivery to sheep was quantified using plasma cotinine levels, measu

286 est intravenous dose used (24 mg/kg), in 5/6 sheep we observed a novel effect of ketamine, namely the

287 ize and short or thin tails), and fat-tailed sheep, we found an overrepresentation of MSY lineages y-

288 ontrol (CON) (n = 8) and IUGR (n = 13) fetal sheep were catheterized with aortic and femoral catheter

289 The homozygous sheep were found to have significantly reduced PPT1 enzy

290 Three PPT1 homozygote sheep were generated by insertion of a disease-causing P

291 could be eliminated if all footrot-affected sheep were removed and fade out of D. nodosus occurred i

292 fore, rumen fluid from cannulated cattle and sheep were used as inocula to examine in vitro the effec

293 of M. ovipneumoniae strains within domestic sheep, whereas only one or a few strains tend to circula

294 most recent is hypothesised to have included sheep with markedly improved wool production.

295 on, and the reflex response to hemorrhage in sheep with normotension (control) or with hypertensive c

296 A total of 8 normal sheep and 8 sheep with pacing-induced HF received incremental intrav

297 fully applied to flow-sorting chromosomes of sheep, with a focus on isolation and sequencing of the o

298 ent strategies to persist and spread between sheep within and between flocks.

299 , we show that a minimum group size of eight sheep would provide sufficient power to observe signific

300 ncluding mice, rats, ferrets, rabbits, pigs, sheep, zebrafish, and fruit flies, have all been used to