ライフサイエンスコーパス: side

1 a tetra-palladium-oxo unit grafted on either side.

2 flat on the right side, and flat on the left side.

3 es and longer paths form on the urinary pole side.

4 therapy; sham therapy was given to the other side.

5 of their axons to light on the contralateral side.

6 shes is shaped like an airfoil turned on its side.

7 tly and systematically switched from side to side.

8 usion produced damage mainly in the occluded side.

9 angle was significantly lower on the paretic side.

10 in central circuits, and on the postsynaptic side.

11 BE cells secrete EVs to the apical and basal side.

12 most cue cells only responded to cues on one side.

13 different photocatalytic activities on both sides.

14 Of the 128 (30.9%) patch-free operated sides, 4.7% (n = 6) suffered postoperative bleeding.

15 The lower limit of the 2-sided 90% confidence interval was -1.724 letters, which

16 red with enoxaparin with risk differences (1-sided 95% CIs) of 10.6% (95% CI, -1.2% to infinity) at t

17 Neolithic lineages, whereas on the paternal side a Steppe ancestry is clearly visible.

18 1-sided P = .068) and met the prespecified 1-sided alpha of 0.10.

19 int was progression-free survival with a one-sided alpha of 0.20.

20 n 5 years, 2-year minimum follow-up, and one-sided alpha of 5%, 80% power was calculated.

21 -S anastomosis and stapled ileocolic side-to-side anastomosis.

22 roduction stages (raw, roasted, and winnowed side and end products) by high-performance liquid chroma

23 Based on our results, sea side and land side tritium leakage monitoring systems sh

24 ic oxygen reduction on the cathodic membrane side and subsequently terminated by H(2)O(2) oxidation o

25 ry DNAs, one to the base sequence on t-amide side and the other to the bases on the Calpha side chain

26 metastases were counted on CT from 22 right-sided and 64 left-sided colon tumours.

27 rone on a massage pillow), flat on the right side, and flat on the left side.

28 d on the mirrored image of the contralateral side, and the posterior surface contour was based on orb

29 ensins that perform one-sided, symmetric two-sided, and asymmetric two-sided extrusion.

30 cated that the proposed strategy allowed the side arms of H(1)/H(2) to be sealed into the RNA sequenc

31 the rapid decay (0.6 ns) of a small spectral side band, the broad emission line shape is constant to

32 but promotes both in-layer and out-of-layer side-branching, in particular resulting in the helical g

33 for comparison, we perform FLOW-MAP analysis side by side with other single-cell analysis methods, to

34 fferent materials strategies, we allow for a side-by-side comparison of the most promising strategies

35 irrors the hydrogen bonding potential of the side chain (C-H < S-H < O-H).

36 The rotameric preferences of R1 side chain are determined by the type of the secondary s

37 hains but different functional groups on the side chain are employed to clarify the contributions of

38 Simultaneous optimization of side chain conformations across all conformations increa

39 or the most part a much greater diversity of side chain conformations is observed.

40 ond, we showed that PTP1B (13)C-methyl group side chain fast time-scale dynamics and (15)N backbone f

41 idinium occupies the site of a 'missing' Arg side chain found in other fungal species where (i) the C

42 ins have a different terminal-functionalized side chain incorporated into the glucuronic acid unit th

43 PE phenyl ring containing the antiestrogenic side chain of endoxifen or a free hydroxyl.

44 y simulations, we observed that the carboxyl side chain of Glu89 (located along the arch motif in hEx

45 install reactive hydrazide handles onto the side chain of internal glutamine residues.

46 the N-substitution of the 3-phenylisoserine side chain of taxoids.

47 e preferences stand in stark contrast to the side chain populations observed for these sugars both in

48 didate for hexanoic acid activation (Taxol C side chain), and TmAAE4 as suitable candidate for esteri

49 for the activation of butyric acid (Taxol D side chain), TmAAE13 as the best candidate for generatin

50 c acid (N-debenzoyl-N-(2-methylbutyryl)taxol side chain), TmAAE15 as a highly efficient candidate for

51 nerating a CoA ester of tiglic acid (Taxol B side chain), TmAAE3 and TmAAE13 as suitable for the acti

52 terification of benzoic acid with CoA (Taxol side chain).

53 vities, suggesting that the structure of the side chain, triterpenoid core, and oligosaccharide domai

54 sponsive polymer with an amide moiety on its side chain, was studied in aqueous solutions with a seri

55 the individuality of the different aminoacid side chain.

56 ide and the other to the bases on the Calpha side chain.

57 gether in a fixed orientation in the monomer side chain.

58 and C rings are ~7.0 angstrom from the F673 side-chain 4-(19)F.

59 how that csdAB and csdCD are involved in Glc side-chain addition on the CWPS components rhamnan and p

60 Genetic enhancement of the alkyl side-chain could lead to the development of novel chemic

61 Here the fast side-chain dynamics of the alpha-helical sensory rhodops

62 ble for hydrazide linkers containing various side-chain functionalities and topicities.

63 elling, attributed to the hydroxylated alkyl side-chain functionalization.

64 Bioinformatics studies to match side-chain orientations of a novel hydantoin triazole ch

65 of a mononuclear iron coordinated by two Tyr side-chain phenolates and one carboxylate from Glu.

66 , we examined whether the differences in the side-chain polarity of these AAs trigger distinct allost

67 the overall conformation of backbone and key side-chain residues.

68 the stability of the conventional amino acid side-chain-protecting groups, t-Bu, Boc, Trt, and Pbf, a

69 ies including head-to-tail cyclization (C1), side-chain-to-tail cyclization (C2), and a disulfide bon

70 that p.D50A changed locations of amino acid side chains altering RNA binding sites in the RRM.

71 depends on the identity of the inserted Nte side chains and not on Nte orientation.

72 and its paralog CBP acetylate histone lysine side chains and play critical roles in regulating gene t

73 , with coupling of the dynamics of histidine side chains and those of remote key backbone elements of

74 ), are modulated by the nature of amino acid side chains as well as by local solvent exposure.

75 This action buries ionic side chains away from the bulk water, while allowing wat

76 cisely dictated by the placement of reactive side chains during the reductive amination reaction.

77 olecular Modeling Suite to recombine protein side chains in these contact pools to generate hundreds

78 yphenyl)porphyrin cobalt(II) (TMPPCo) on the side chains of an ionomer (polyfluorene, PF) to obtain a

79 rosides in C. elegans, instead activates the side chains of certain ascarosides for shortening throug

80 M binding to an internal ring of hydrophobic side chains of L279 residues.

81 sed by the specific interactions between the side chains of the Nte residues and the FimA core and no

82 are poorly activated by Rca, indicating the side chains of these residues form a critical interactio

83 footprint broadly several amino acid residue side chains on the time scale of submilliseconds.

84 ngle substitutions and deletions to identify side chains that are critical for the inhibitory binding

85 ns of glycosidase inhibitors with restricted side chains that confer higher selectivity and/or affini

86 mbrane systems, and (ii) "rigid" dendronized side chains to enhance the membrane lytic property.

87 es this tunnel and leverages upon the gating side chains triggering the CD loop to furl, which moves

88 acids with different lengths of hydrophobic side chains.

89 degrees C for conjugated polymers with alkyl side chains.

90 y, although with a reduced content of chiral side chains.

91 ount of alkyl side-chains with compact bulky side-chains (CBS).

92 arabinose level suggests that long arabinan side-chains maintain cell wall flexibility in water defi

93 atically replacing a certain amount of alkyl side-chains with compact bulky side-chains (CBS).

94 We computed the percentage of Left-sided Choice (LC).

95 the dorsal and lateral tracts on the injured side closely tracked measurements of the behavioral reco

96 ounted on CT from 22 right-sided and 64 left-sided colon tumours.

97 materials strategies, we allow for a side-by-side comparison of the most promising strategies for ena

98 the placebo group (difference, 3.5%; [90% 1-sided confidence limit for benefit, -0.9%]; P = .16; [97

99 limit for benefit, -0.9%]; P = .16; [97.5% 1-sided confidence limit for harm, 10.2%]; P = .84).

100 s while keeping the distance of the unguided side constant to determine the influence of spatial geom

101 oly(3-octylthiophene) [POT], that is in back-side contact.

102 es of 350-600 nm in diameter at their apical side, continuously internalizing their surrounding mediu

103 conduit' of lesser importance than its left-sided counterpart.

104 The fascicle gear ratio on both sides decreased as the ankle became dorsiflexed, but the

105 of M-L delta and phi interactions; "head-to-side" delta and "side-to-side" phi back-bonding, found i

106 On the computational side, density functional theory and noncovalent interact

107 hippocampal formation of the Atlantic white-sided dolphin (AWSD) with the view to understand similar

108 rection of permeation from concave to convex side due to a difference in metal-carbon bonding at the

109 aclitaxel induces peripheral neuropathy as a side effect of cancer treatment.

110 tion, it can lead to tinnitus as an unwanted side effect.

111 nts vary, however, in both effectiveness and side-effect profile.

112 ral neuropathy is a debilitating and painful side-effect that can severely impact an individual's qua

113 mained high even with the potential for mild side effects (70%).

114 owever, their clinical benefit is limited by side effects and addictive potential.

115 ug-delivery system to reduce the undesirable side effects and enable the clinical application of Ade

116 e currently used in the clinic to reduce the side effects and improve the pharmacokinetic profile of

117 an and model systems, without cardiovascular side effects and improved spastic gait disorders after b

118 ective GPCR ligands with potentially reduced side effects and provides an attractive probe molecule a

119 Because antiviral drugs can have side effects and show reduced clinical effectiveness whe

120 , use of CsA is associated with more serious side effects and worse clinical outcomes than FK506.

121 leukemia (ALL) is efficacious, but long-term side effects are concerning.

122 Another limitation is the side effects associated with the treatment of chemothera

123 ive, pan-HDAC inhibitors, exhibiting adverse side effects at therapeutic doses.

124 cy and cause neurological and cardiovascular side effects because they target upstream regulators of

125 current therapies are mostly efficient, the side effects can result in therapy stop, which makes the

126 The main side effects comprised transient hematotoxicity, such as

127 istinguish the electron harvesting from some side effects due to quinones in real time.

128 hese methods in cellular populations without side effects has remained challenging.

129 herogenesis and reduced hypertriglyceridemia side effects in comparison to the free drug and blank sH

130 leted a significant proportion of Tregs, the side effects in the presence of ART prevent their clinic

131 Due to its untargeted nature and the severe side effects it can cause, numerous nanomedicine approac

132 stant to these medications, while off-target side effects lead to dismal patient adherence to lifelon

133 well tolerated, with no immediate or delayed side effects observed after injection.

134 cations due to its own comorbidities and the side effects of its treatment.

135 Early side effects of radioiodine therapy (typically mild pain

136 ptor antagonists for both reduction of motor side effects of SSRIs and augmentation of therapeutic an

137 striae and secondary adrenal suppression as side effects of steroids.

138 echanistic insights related to the metabolic side effects of these widely used drugs.

139 Meanwhile, there are no side effects on normal tissues due to the local treatmen

140 fe-long immunosuppression and its associated side effects preclude intestinal transplantation if moti

141 chanisms responsible for severe inflammatory side effects remain poorly understood.

142 However, untoward side effects such as tolerance, dependence, respiratory

143 orithm learns latent signatures of drugs and side effects that are both reproducible and biologically

144 e for new, efficacious opioids devoid of the side effects that have made them the scourge of humanity

145 rombocytopenia following systemic injection, side effects that might be eliminated by a gut-restricte

146 While side effects were common and mostly mild to moderate, so

147 Side effects were more reported in the HCQ group than in

148 ts potential specificity and lack of adverse side effects when compared to more traditional modes of

149 ntly available treatment, based on efficacy, side effects, and cost.

150 ntraceptive choices and their effectiveness, side effects, and impact on psychiatric symptoms.

151 in treating a disease, while limiting their side effects, is of broad significance.

152 nding of their safety profiles and potential side effects, making them easier to fast-track to clinic

153 d home spirometry, reporting of symptoms and side effects, patient-reported outcomes, information, a

154 release profile can be used to limit adverse side effects, reduce dosing frequency, and potentially i

155 to deplete CART19 cells to reduce long-term side effects, such as B-cell aplasia.

156 in rodents and lacked cardiac and behavioral side effects, suggesting its potential for use in pharma

157 cluded medication burden, but not medication side effects.

158 mylase inhibition generally causes undesired side effects.

159 0.06) Mn(0.03) )O(2) (NCM9163), with minimal side effects.

160 nicity while at the same time reducing local side effects.

161 photodynamic therapy (X-PDT) with negligible side effects.

162 cells via C-type lectin receptors and reduce side effects.

163 improve therapeutic efficacy while reducing side effects.

164 n of an exogenous dye with potential adverse side effects.

165 hageal reflux can be followed by troublesome side effects.

166 has varying efficacy and causes significant side effects.

167 y to develop more selective drugs with fewer side effects.

168 rties of MOR agonists while avoiding certain side effects.

169 ly effective and associated with significant side effects.

170 ction did not differ between groups, nor did side effects.

171 tiated early in illness but can have serious side effects.

172 accentuated therapeutic activity and reduced side effects.

173 t controls and reduces severe BTZ-associated side effects.

174 s/no questions to determine reflux symptoms, side-effects and satisfaction with surgery.

175 their ability to tackle cancers and for the side-effects caused by the drugs.

176 ernative solutions are required to avoid the side-effects of using these drugs.

177 ain, and was associated with higher rates of side-effects than placebo.

178 are many men radiotherapy and its associated side-effects.

179 are expensive, less feasible or have harmful side-effects.

180 Staphylococcus aureus bacteremia, and right-sided endocarditis infections associated with S. aureus,

181 rsal and intact lateral tracts on the lesion side exhibited prominent disruptions in fiber orientatio

182 contexts (e.g. surrounding 3 bases on either side) explains an additional 4% of shared variants.

183 ixtures of condensins I and II, coupling two-sided extrusion and stable chromatin binding by condensi

184 ded, symmetric two-sided, and asymmetric two-sided extrusion.

185 echanism for decreased consumption, straight-sided glasses elicited more 'pursed' lip embouchures, wh

186 nd were found primarily in the source and up/side-gradient areas (75%), likely due to preferential hy

187 alpha-helices at the outer edges, and basic side grooves near the dimer interface.

188 ow H(2)O-diester H-bonding, thus forcing nBA side groups to adapt L-shape conformations, generating s

189 eversible hydrogen electrode) and a cathodic-side (half-cell) ethylene power conversion efficiency of

190 serve MBP to insert into its bilayer leaflet side in case of the diseased lipid mixture, whereas ther

191 data across multiple species, and arbitrary side information in the form of kernels (e.g. from prote

192 by H(2)O(2) oxidation on the anodic membrane side, is crucial for (1)O(2) generation.

193 Review the long-term outcomes of the side-to-side isoperistaltic strictureplasty (SSIS) and its effec

194 We report on a new side-to-side isoperistaltic strictureplasty (SSIS), the Michelas

195 ates (NHPs) demonstrated that the right-hand-side labeled ligand [(11)C]-1R (CHDI-180R) is a suitable

196 d the Cochran-Mantel-Haenszel test, with a 2-sided level of 10%.

197 Theory indicates that symmetric two-sided loop extrusion can achieve such compaction, but re

198 While one-sided loop extrusion cannot reproduce these phenomena, v

199 lopment and performance of a portable single-sided magnetic-resonance sensor for grading liver steato

200 ir loading sites and extrude loops in a 'one-sided' manner.

201 illary channel to retain the sample, and two side mirrors to monitor inside the channel.

202 On a track with cues on left and right sides, most cue cells only responded to cues on one side

203 idence of the colloidal stability of side-to-side nanorod clusters.

204 nd striatum as well as a predominantly right-sided network of regions involving the orbitofrontal cor

205 ty between pairs of configurations on either side of a mechanical critical point.

206 by reinforcing SYP-1 phosphorylation on one side of each crossover only when threshold levels of cro

207 ess key benefits and costs on the production side of genetically modified (GM) and organic corn syste

208 MSCs were seeded on the extraluminal side of hollow fibers within a bioreactor where they ind

209 that the IUTD enters from the extracellular side of OmpF and translocates to the periplasm where the

210 hly polarized and present only at the apical side of polarized cells.

211 Interestingly, DNA flanking the RNA-5' side of R-loops is not intrinsically unstable.

212 bing by decreasing the area per lipid on the side of the bilayer to which the salt was exposed.

213 Pol31 and Pol32 are positioned off to the side of the catalytic Pol3-PCNA-DNA axis.

214 cally extending from the apical to the basal side of the developing cortex.

215 ature-resident cells that patrol the luminal side of the endothelium.

216 atial localization of the EGFR to the apical side of the FCs at early stages depended on the TGFalpha

217 of its trimerisation region to dock onto the side of the helicase assembly formed by Cdc45 and GINS.

218 Then, most fluorescence is detectable on the side of the higher-index substrate, and a large fraction

219 behavior, preferring to feed using the right side of the jaw.

220 ed from the extracellular to the cytoplasmic side of the membrane, is rate limiting to transport.

221 a central substrate binding pocket to either side of the membrane.

222 icated planar electrodes projecting into one side of the microfluidic channel and is easily integrate

223 stimulation, Aifm2 associates with the outer side of the mitochondrial inner membrane.

224 ster repair of UV damage occurring on the 5' side of the nucleosomal DNA.

225 pecific phospholipids found on the cytosolic side of the plasma membrane.

226 esting that MDIMP binds to the extracellular side of the pore.

227 Substitution of an A-rich sequence on the 5' side of the terminator to uridines strengthened the bind

228 gger longer lasting wave trains on the front side of the tropical cyclones.

229 rtilization and then to the future posterior side of the zygotes in a later phase of cytoplasmic reor

230 fruit were analyzed based on citrus season, side of tree evaluated, height within the canopy, tree h

231 ill in which participants were guided on two sides of a triangle and then found their back way to ori

232 glipizide) were on opposite sides of and could not exclude the null (glimepiride: aH

233 hrough secondary nucleation occurs along the sides of fibrils, which become heavily decorated under t

234 10 at the outside of the up azimuth on both sides of loop pipe outlets, 4 regions from Nos.

235 ding domains that interact with the opposite sides of short DNA gaps.

236 se that PKD2-mastigoneme arrays, on opposing sides of the cilium, could perceive forces during ciliar

237 gamma-H2AX spreads as far as ~50 kb on both sides of the lesion within 1 h; but the kinetics and dis

238 D567/S566 and E491/S527, located on opposite sides of the murine Esco2 active site cleft, are critica

239 r), each 1-1.5 mm deep, were created on both sides of the palate.

240 G' slopes on both sides of the peak (S2, S3) and following the decline (S4

241 Hundreds of parallel barbs branch from the sides of the rachis.

242 n sensitivity of B. thetaiotaomicron are two sides of the same coin.

243 dency of participants to under-encode guided sides of the triangles and an influence of past trials o

244 h the same composition as 2-Tb but with both side-on and end-on bonding of the N(2) unit in the same

245 ity of dioxygen binding to the iron ion in a side-on mode.

246 ere the tooth is held in place on the labial side only.

247 kinetics of efflux was also studied in right-side-out membrane vesicles.

248 p (multiple comparison procedure-modeling, 2-sided p < 0.001) was found in the reduction of wake afte

249 ctively (HR, 0.54; 95% CI, 0.34 to 0.88; two-sided P = .01).

250 1.57; 95% confidence interval, 0.87-2.82; 1-sided P = .068) and met the prespecified 1-sided alpha o

251 odds ratio, 1.06; 95% CI, 0.51 to 2.21; one-sided P = .44).

252 the 97.5% confidence interval [CI], -3; one-sided P = 0.024).

253 7.6 and 5.6 months (HR, 0.74, 0.61-0.90; one-sided p=0.0014 [not significant]) among patients with CP

254 azard ratio [HR] 0.82, 95% CI 0.70-0.96; one-sided p=0.007).

255 The potential [3+2] side pathway could be suppressed though fine tuning of t

256 eractions; "head-to-side" delta and "side-to-side" phi back-bonding, found in complexes of metallacyc

257 ts dimethylbenzimidazole tail splayed into a side pocket and its corrin ring buried.

258 thick bipolar and, for smooth muscle myosin, side-polar filaments.

259 The MRI images demonstrated that side positioning gives better contact between the gas bu

260 ial pressures, toward normal levels of right-side pressure (about 20 mmHg) measured by RHC.

261 et their use remains sparse due to undesired side-processes.

262 An unexpected side product formed through 4-exo-trig radical cyclizati

263 ispecific antibodies and potential mispaired side products, in cell culture media, or other complex m

264 on could lead to a larger number of possible side products, the optimization of the methodology and t

265 ation (NaI) and cogenerating perfluoroalkene side products.

266 erved between TA-LG co-contraction (affected side, r = 0.557, p = 0.020; contralateral side, r = 0.62

267 ed side, r = 0.557, p = 0.020; contralateral side, r = 0.627, p = 0.007) and the Oswestry disability

268 e formation of aspartimide as an undesirable side reaction that occurs during Fmoc solid-phase peptid

269 sorption, and as a result, photobleaching or side reactions of the fluorophore are not observed.

270 Here, electrochemical side reactions with molecular oxygen are shown to occur

271 pects, scope, and limitations, in particular side reactions, are discussed.

272 llenging due to its complexity and intrinsic side reactions.

273 ces, they are susceptible to electrochemical side-reactions with molecular oxygen during device opera

274 es afford primarily beta-hydride elimination side reactivity.

275 large impedance mismatches to realize total side reflection with negligible transmission and absorpt

276 s, and VAMP-7 recapitulates light-cytometric side scatter.

277 clude uniform downscaling on the presynaptic side.SIGNIFICANCE STATEMENT To date, compensatory adapta

278 finishing generates a considerable amount of side-stream (FSS) with great potential for biotechnologi

279 The lead-absorbing films on both sides swell to absorb the lead, rather than dissolve, wh

280 erse dynamics of condensins that perform one-sided, symmetric two-sided, and asymmetric two-sided ext

281 Analyses used 2-sided t tests, Wilcoxon rank sum tests, Spearman correla

282 Two one-sided tests with equivalence bounds of 0.5 (Cohen d effe

283 On the experimental side, the hydride reduction of 3-substituted cyclobutano

284 tillator array was coupled at the nonreadout side to a light-guide (one 4-to-1 module with a uniform

285 explicitly and systematically switched from side to side.

286 tes on both the presynaptic and postsynaptic sides to maintain target cell activity.

287 The Michelassi II, or the end-to-side-to-side-to-end strictureplasty, is a variant of the origina

288 (SSIS), the Michelassi II or end-to-side-to-side-to-end strictureplasty, performed with discontinuou

289 ing Kono-S anastomosis and stapled ileocolic side-to-side anastomosis.

290 Review the long-term outcomes of the side-to-side isoperistaltic strictureplasty (SSIS) and i

291 We report on a new side-to-side isoperistaltic strictureplasty (SSIS), the

292 irect evidence of the colloidal stability of side-to-side nanorod clusters.

293 phi interactions; "head-to-side" delta and "side-to-side" phi back-bonding, found in complexes of me

294 The Michelassi II, or the end-to-side-to-side-to-end strictureplasty, is a variant of the

295 replasty (SSIS), the Michelassi II or end-to-side-to-side-to-end strictureplasty, performed with disc

296 Based on our results, sea side and land side tritium leakage monitoring systems should be streng

297 s not clear whether integrating the opposing sides under a common formal framework will yield new ins

298 he membrane, particularly on the cytoplasmic side, where autoacylation occurs.

299 rt layer and expels electrons toward cathode side, which reduces the charge recombination there.

300 arison, we perform FLOW-MAP analysis side by side with other single-cell analysis methods, to illustr