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1 s through a PLC-, calcium- and PKC-dependent signal transduction cascade.
2 requires the canonical H2AX-MDC1-RNF8-RNF168 signal transduction cascade.
3 ain factor, and activation by an ABA-induced signal transduction cascade.
4 the bound ligand and initiate the downstream signal transduction cascade.
5 )-1 is an important component of the insulin signal transduction cascade.
6 activity via a cAMP-dependent protein kinase signal transduction cascade.
7 are downstream effectors in the Eph-induced signal transduction cascade.
8 machinery requires an intact quorum-sensing signal transduction cascade.
9 activated by an abscisic acid (ABA)-induced signal transduction cascade.
10 via the phosphatidylinositol 3 (PI3)-kinase signal transduction cascade.
11 erum withdrawal by inhibiting the PI3-kinase signal transduction cascade.
12 ng in amplification of the inflammatory pain signal transduction cascade.
13 se mechanism is involved in the PAF-mediated signal transduction cascade.
14 s of the ER membrane serve to integrate this signal transduction cascade.
15 ne of regulation of the EGF receptor-induced signal transduction cascade.
16 ification of the dorsoventral axis through a signal transduction cascade.
17 thiol oxidation of a proximal element in the signal transduction cascade.
18 synthetic enzymes by blocking the antecedent signal transduction cascade.
19 case has a novel DRC function as part of the signal transduction cascade.
20 the cell integrity pathway, a conserved MAPK signal transduction cascade.
21 H2O2 signaling bears hallmarks of a regular signal transduction cascade.
22 ress response independently of the DegS/RseA signal transduction cascade.
23 all FGF activities depend on this canonical signal transduction cascade.
24 se and identifies new molecular steps in the signal transduction cascade.
25 investigate the functional components of the signal transduction cascade.
26 e kinase kinase (DLK MAPKKK) to regulate the signal transduction cascade.
27 signaling pathway, an evolutionary conserved signal transduction cascade.
28 loop between miR-1 expression and the IGF-1 signal transduction cascade.
29 y govern kinase activity through an internal signal transduction cascade.
30 a converging input for two Zn(2+)-dependent signal transduction cascades.
31 ositol pentakisphosphate kinases in plant Pi signal transduction cascades.
32 d second messengers, which initiate multiple signal transduction cascades.
33 anes and act as second messengers in diverse signal transduction cascades.
34 ncentrations are key events that can trigger signal transduction cascades.
35 K-STAT pathway is one of the best understood signal transduction cascades.
36 anisms, we show that ApoE broadly stimulates signal transduction cascades.
37 oteins that enhance specificity and speed in signal transduction cascades.
38 osphate (PIP2) that serves multiple roles in signal transduction cascades.
39 e activity and flux through growth-promoting signal transduction cascades.
40 s that dysregulate phosphorylation-dependent signal transduction cascades.
41 itiation factor 2 alpha (eIF2alpha) or other signal transduction cascades.
42 ion, autophosphorylation, and stimulation of signal transduction cascades.
43 mination of its role in nutrient sensing and signal transduction cascades.
44 membrane, resulting in downstream effects on signal transduction cascades.
45 for cellular morphogenesis and intracellular signal transduction cascades.
46 he regulation of proliferative and apoptotic signal transduction cascades.
47 the taste buds, leading to the activation of signal transduction cascades.
48 rected by cell-cell interactions mediated by signal transduction cascades.
49 play an important role in the regulation of signal transduction cascades.
50 roteins that bind and organize components of signal transduction cascades.
51 Ac as a regulatory modification important to signal transduction cascades.
52 ctionally regulated by a number of different signal transduction cascades.
53 as proteins contributes to their activity in signal transduction cascades.
54 Nerve growth factor initiates several signal transduction cascades.
55 abolism plays a critical role in a number of signal transduction cascades.
56 sis reveals the multiple effects of space in signal transduction cascades.
57 oordinated by a poorly understood network of signal transduction cascades.
58 pathogenic fungi, given their involvement in signal transduction cascades.
59 es of virus infection and initiate antiviral signal transduction cascades.
60 uli by mediating the flux through downstream signal transduction cascades.
61 fibroblasts significantly amplifies IL-1beta signal transduction cascades.
62 erizing its receptor (FGFR), which activates signal transduction cascades.
63 inase that modulates the activity of several signal transduction cascades.
64 ized sensory cells to activate intracellular signal transduction cascades.
65 numerous factors, including input from other signal transduction cascades.
66 interacting with terminal members of several signaling transduction cascades.
67 How are TRP channels regulated by signal transduction cascades?
68 biochemical strategy to design RNA-mediated signal transduction cascades able to sense small molecul
69 ate that EIN5 is a component of the ethylene signal transduction cascade acting downstream of CTR1 th
70 indings suggest a revised model in which the signal transduction cascade activated by cross-linking o
71 this study was to characterize the mitogenic signal transduction cascade activated by the 5-HT(2B) re
72 hGHR bioassay demonstrated initiation of the signal transduction cascade, after binding of all invest
73 ata suggest that inhibition of the MEK-->ERK signal transduction cascade alleviates cell cycle depend
74 ration ([Ca2+]cyt) are central regulators of signal transduction cascades, although the roles of indi
75 bes the major signalling pathways in the TCR signal transduction cascade and focuses on proximal even
76 myotomally derived FGFs act through the MAPK signal transduction cascade and in particular, ERK1/2 to
77 oteins involved in the B-cell receptor (BCR) signal transduction cascade and inhibits the antigen-ind
78 pport the intimate involvement of PECAM-1 in signal transduction cascades and also suggest that caspa
79 nscription factors are commonly activated by signal transduction cascades and induce expression of ma
80 anscription factor is activated by oncogenic signal transduction cascades and its function is critica
81 These novel interactions may amplify the signal transduction cascades and molecular events that l
82 by orchestrated mechanisms including several signal transduction cascades and morphologic transformat
83 ptor agonists/antagonists, the modulation of signal transduction cascades and new and expanded uses f
84 r are highly coordinated processes utilizing signal transduction cascades and post-translational modi
85 duplicate pairs are enriched for members of signal transduction cascades and transcription factors.
86 r dsRNA-binding domains led to activation of signal transduction cascades and up-regulation of host g
87 residue of proteins involved in a variety of signal transduction cascades, and other critical cellula
88 respect to the phot-, cry-, and phy-mediated signal transduction cascades, and possible involvement o
90 anges, including neurotransmitter receptors, signal transduction cascades, and target proteins of dop
91 Ca2+ can activate and regulate a variety of signal transduction cascades, and the influx of Ca2+ thr
94 the Ca(2+) signal in the Pep immune defense signal transduction cascade, as is the case with BRASSIN
95 To identify specific genes involved in the signal transduction cascade associated with nonhost dise
96 ite arborization in vitro and identified the signal transduction cascade associated with this effect.
97 rypanosome DNA stimulated the induction of a signal transduction cascade associated with Toll-like re
99 etects it, how four core Psp proteins form a signal transduction cascade between the IM and the cytop
100 s with ARMCX3 and raise the possibility of a signal transduction cascade between the nucleus and mito
102 he ER plays a key role in the TNF-R-mediated signal transduction cascade by acting as a site of assem
103 ular signal, GPCRs trigger the intracellular signal transduction cascade by activating a heterotrimer
105 t is the activation of the mitogen-activated signal transduction cascade by mutations in the RAS gene
106 STUV operon is induced via a three-component signal transduction cascade composed of RhuI, RhuR, and
108 cid deprivation of cells in culture causes a signal transduction cascade consisting of activation of
109 s underlie the activation of light-sensitive signal transduction cascades controlling these responses
110 and suggest that components of the olfactory signal transduction cascade could be targets of circadia
111 onal change by molecular interactions in the signal-transduction cascade could be used to control acc
113 es have been shown to modulate intracellular signal transduction cascades critical for cell growth an
114 of the unripe host fruit initiates defensive signal-transduction cascades, culminating in accumulatio
115 We conclude the intensity of activation of signal transduction cascades determines cell lineage seg
116 daptor protein CrkII plays a central role in signal transduction cascades downstream of a number of d
118 e side and signal transducer (receptor), the signal transduction cascade (effector proteins, second m
119 xis, and development per se but is part of a signal transduction cascade essential for system initiat
121 plays an essential role in the TCR-mediated signal transduction cascade for expression of certain cy
122 g in CREB phosphorylation represents a novel signal transduction cascade for regulating cellular gene
123 vation of MMP2, and (ii) a receptor-mediated signal transduction cascade for the tyrosine phosphoryla
124 ks5 form a macromolecular complex to mediate signal transduction cascades for the regulation of cell
128 ify the structural elements involved in this signal transduction cascade, here we optimized a cGMP-ba
129 signal-regulated kinase (Ras-ERK) pathway, a signal transduction cascade implicated in behavioral pla
130 abilities of these molecules to activate the signal transduction cascades implicated in the regulatio
131 o assess the first step in the intracellular signal transduction cascade in a functional assay follow
132 ast three distinct pathways within a complex signal transduction cascade in response to a variety of
133 vation of a protein phosphorylation-mediated signal transduction cascade in response to symbiotic sig
136 receptor (BCR) leads to the initiation of a signal transduction cascade in which the earliest events
137 rt the model that derangement of hippocampus signal transduction cascades in AD arises as a consequen
138 s a mechanical trigger to activate bacterial signal transduction cascades in many motile bacteria upo
139 ed long-lasting activation of insular cortex signal transduction cascades in novel taste learning.
140 ided proof of principle that interruption of signal transduction cascades in patients with colorectal
142 e in the regulation of growth factor-induced signal transduction cascades in the epithelium, and ErbB
143 up-regulation of molecules related to these signal transduction cascades in the liver by quantitativ
144 in their activation loop, are components of signal transduction cascades in which sequential activat
145 her biological outcomes of the Crk-activated signal transduction cascades include the modulation of c
146 erse design principles for engineering scRNA signal transduction cascades including reactant stabilit
147 receptor tyrosine kinases and components of signal transduction cascades including the extracellular
148 beta1AR) and other components of the beta1AR signal transduction cascade, including adenylate cyclase
150 oxygen species are involved in the mitogenic signal transduction cascades initiated by several growth
151 ute to vascular diseases, we have examined a signal transduction cascade involved in H(2)O(2)-induced
152 cond set of experiments, we investigated the signal transduction cascade involved in this response, a
153 tumor cell motility through a nonproteolytic signal transduction cascade involving activation and pho
154 ation of the NMDAR NR2A subunit in RVM via a signal transduction cascade involving IP(3), PKC, and Sr
155 y are regulated by thyroid hormone through a signal transduction cascade involving the phosphatidylin
156 G-protein-coupled receptors (GPCRs) triggers signal transduction cascades involving heterotrimeric G
158 AvrBs2 by plants expressing the Bs2 gene, a signal transduction cascade is activated leading to a ba
160 kpoint signaling, arguing that a traditional signal transduction cascade is integral to spindle check
162 alpha mutants reveals that activation of the signal transduction cascade is sufficient to cause axona
163 Deregulation of PI3K/Akt and Raf/Mek/Erk signal transduction cascades is one of the principal cau
165 how that OMP is a modulator of the olfactory signal-transduction cascade, its biochemical role is not
166 amage, eukaryotic cells activate a conserved signal transduction cascade known as the DNA damage chec
167 nase in the mitogen-activated protein kinase signal transduction cascade known to regulate inflammato
168 king a cAMP-mitogen-activated protein kinase signal transduction cascade leading to an increase in VP
169 ptide receptor-like-1 (FPRL1)) to initiate a signal transduction cascade leading to cell activation a
170 ses the environmental cue that initiates the signal transduction cascade leading to changes in cellul
171 ppression occurs upstream of JNK, within the signal transduction cascade leading to JNK activation, w
172 IFNs are secreted cytokines that activate a signal transduction cascade leading to the induction of
173 PV IgG binding to dsg3 activates desmosomal signal transduction cascades leading to (i) p38MAPK and
174 y studied because they initiate and regulate signal transduction cascades leading to a variety of fun
175 se family, has emerged as a key regulator of signal transduction cascades leading to the activation o
177 solic secondary messenger is involved in the signal transduction cascade linking CLV3/CLV1 to control
180 hed regulators of the Ras/Rap/ERK MAP kinase signal transduction cascade, matrix-enriched CalDAG-GEFI
181 ellular location of multiple components of a signal transduction cascade may constitute a novel mode
182 data suggests that targeting the RAS/MEK/ERK signal transduction cascade may provide a potential ther
185 mselves or steps in the post-P2Y(1) receptor signal transduction cascade might be potential therapeut
186 e, suggesting that distinct co-activators or signal transduction cascades not found in yeast are requ
187 ndicate that AdV inhibition of the IFN-gamma signal transduction cascade occurs through loss of ligan
188 lements functional in the pheromone response signal transduction cascade of model fungal organisms.
190 s appear to involve disruption/regulation of signal transduction cascade of rHuIL-1beta upstream of m
191 d in which there are three distinct Che-like signal transduction cascades; one that is involved in ch
193 i2, and era1, negative regulators of the ABA signal transduction cascade or for cell cycle components
194 se findings illuminate flagellar adaptation, signal transduction cascade organization, and fertility.
195 n activation of the 7TM receptor GPR30, with signal transduction cascades (PI3K and MAPK) converging
196 factors (Pitx-3 and CBP), and components of signal transduction cascades (Pip-1) are under direct or
198 ation and bone resorption through a cellular signal transduction cascade, possibly through its intera
200 ation; (3) the activation state of the IGF-1 signal transduction cascade reciprocally regulates miR-1
202 yl switches' to reversibly modulate specific signal transduction cascades regulating downstream prote
203 el in which Zpr1 mediates both EGFR and FGFR signal transduction cascades required for lumen formatio
204 and external signals, which activate complex signal transduction cascades resulting in highly dynamic
205 to the inflammatory response by initiating a signal transduction cascade, resulting in interleukin-8
207 synaptic effects are secondary to actions on signal transduction cascades shared by numerous neurotra
208 Fr and Ha-ras, both of which act in the same signal transduction cascade, stimulated urothelial hyper
210 at alpha 7 nAChRs have in regulating various signal transduction cascades, synaptic plasticity, and m
211 genes encoding components and regulators of signal transduction cascades than at inducible downstrea
212 cellular unfolded protein response (UPR), a signal transduction cascade that acts to modulate transl
213 udding yeast mitotic exit network (MEN) is a signal transduction cascade that controls exit from mito
214 itotic exit network (MEN) is a GTPase-driven signal transduction cascade that controls the release of
217 men of the endoplasmic reticulum activates a signal transduction cascade that culminates in the trans
218 ssess CGRP receptors capable of initiating a signal transduction cascade that differentially activate
219 is minireview, we present an overview of one signal transduction cascade that has garnered attention
220 isms to survive multiple stresses involves a signal transduction cascade that increases the expressio
221 ed BRI1 receptors initiates an intracellular signal transduction cascade that influences various aspe
222 The results indicate the importance of a signal transduction cascade that involves the glutamate
223 nase (PI3K) signaling pathway is a conserved signal transduction cascade that is fundamental for the
224 ies of the spindle checkpoint and initiate a signal transduction cascade that leads to inhibition of
225 ll or B cell receptor by antigen initiates a signal transduction cascade that leads to tyrosine phosp
226 In summary, LIMD2 is a new component of the signal transduction cascade that links integrin-mediated
227 one of the proteins required for the direct signal transduction cascade that modifies membrane dynam
228 eptor (EGFR) lie at the head of a complex of signal transduction cascade that modulates cell prolifer
229 Here, we identify a previously unidentified signal transduction cascade that modulates phosphorylati
230 and Ste20, two p21-activated kinases, form a signal transduction cascade that promotes mitotic exit i
231 transferase system (PTS) is a multicomponent signal transduction cascade that regulates diverse aspec
232 in of the receptor kinase BRI1 to activate a signal transduction cascade that regulates nuclear gene
233 HB-EGF mediates its effects via an EGFR/MAPK signal transduction cascade that regulates the expressio
234 the WD-repeat protein Bub3 are elements of a signal transduction cascade that regulates the kinetocho
235 surface, thereby initiating an intracellular signal transduction cascade that results in the altered
236 ve been implicated as important members of a signal transduction cascade that ultimately regulates dy
237 -protein-coupled receptors (GPCRs) initiates signal transduction cascades that affect many physiologi
238 can be found in (i) the powerful amplifying signal transduction cascades that allow a T cell to resp
239 ts are focused on characterizing the complex signal transduction cascades that are activated by these
240 uch effort has focused on characterizing the signal transduction cascades that are associated with ca
241 nd the resulting influx of cations initiates signal transduction cascades that are crucial to higher
243 e cumulative result of intricately regulated signal transduction cascades that are mediated by cytoki
244 engers at various stages within the multiple signal transduction cascades that are set in motion by a
246 the endoplasmic reticulum (ER) and initiates signal transduction cascades that culminate in changes t
247 and adaptive immune system triggers complex signal transduction cascades that culminate in expressio
248 c agents induce alterations in intracellular signal transduction cascades that culminate in the initi
249 ignant cells by RT initiates one or multiple signal transduction cascades that drive a permanent prol
250 omplex, to detect DNA damage and to initiate signal transduction cascades that employ Chk1 and Chk2 S
251 to metabotropic glutamate receptors induces signal transduction cascades that lead to gene-specific
252 can regulate neurite outgrowth; however, the signal transduction cascades that lead to its physiologi
253 hree mitogen-activated protein kinase (MAPK) signal transduction cascades that share multiple signali
254 this coordination involves the activation of signal transduction cascades that target repair proteins
256 Activation of these receptors induces robust signal transduction cascades that trigger the production
257 by growth factors that activate networks of signal transduction cascades that ultimately lead to the
258 oproteins, such as oncogenic H-Ras, initiate signal transduction cascades that ultimately lead to the
259 ceptor by their respective ligands activates signal transduction cascades that ultimately lead to the
260 cognate response regulator PhoP constitute a signal-transduction cascade that controls inducible resi
262 nsmitter candidates, membrane receptors, and signal-transduction cascades that might constitute the m
263 s a point of convergence of their respective signal transduction cascades, the concomitant action at
264 n order to advance therapeutics and to probe signal transduction cascades, there is considerable inte
265 ceptors regulate transcription by activating signal transduction cascades, these data present a novel
266 e key developmental regulators that engage a signal transduction cascade through receptor tyrosine ki
267 sduced to lateral plate mesoderm in a linear signal transduction cascade through the function of the
269 sense the presence of matrix and activate a signal transduction cascade, thus promoting invasive fil
270 photosynthetic bacterium uses the RegB-RegA signal transduction cascade to control a wide variety of
271 an activated HSCs utilize components of TLR4 signal transduction cascade to stimulate NF-kappaB and J
272 R then stimulates the downstream Src-Mek-Erk signal transduction cascade to ultimately transactivate
273 cancer, and some of these modulate cellular signal transduction cascades to carry out their life cyc
274 y transmitting intracellular instructions by signal transduction cascades to coordinate appropriate r
275 less is known about how these events trigger signal transduction cascades to regulate the transition
276 itically involved in turning off the insulin signal transduction cascade, to assess the role of enhan
277 lly linking monoamine receptor activation to signal transduction cascades, transcriptional regulation
278 Exit Network (MEN), a budding yeast Ras-like signal transduction cascade, translates nuclear position
279 e Drosophila embryo is established through a signal transduction cascade triggered in ventral and ven
280 serve as surrogate receptors for initiating signal transduction cascades, ultimately leading to cell
281 ivity in B. subtilis through perturbation of signal transduction cascades under various stress condit
282 are known to be necessary components of the signal transduction cascades underlying normal synaptic
284 hermore, the range of chemoreceptors and the signal transduction cascade utilized by the GG have rema
285 to the stimulation of multiple intracellular signal transduction cascades via receptor-associated, pr
289 ions as they initiate a unique bidirectional signal transduction cascade whereby information is commu
291 The binding of lysozyme to RsiV triggers a signal transduction cascade which results in degradation
292 facilitated by manipulation of the host cell signal transduction cascades which can impact cell cycle
293 is regulated by the bacterial quorum-sensing signal transduction cascade, which allows bacteria to as
295 tif are very important for activation of the signal transduction cascade, which is necessary for cell
296 drug exerts its effects typically through a signal transduction cascade, which is non-linear and inv
297 ape-complementary coreceptor and initiates a signal transduction cascade, which leads to a variety of
298 ilability' signal to the next protein in the signal transduction cascade, which sits in the inner mem
299 s transmit survival signals through separate signal transduction cascades, which all share the abilit