ライフサイエンスコーパス: signaling complex

1 the interferon response via a mitochondrial signaling complex.

2 phage expression and interaction of TLR4/MD2 signaling complex.

3 pecific chemoreceptors within the chemotaxis signaling complex.

4 n domains, and/or 3) Abl is a scaffold for a signaling complex.

5 ting that GluD1 and mGlu5 may cooperate in a signaling complex.

6 the few known biochemical regulators of this signaling complex.

7 on of K63-ubiquitinated RIP within the TNFR1 signaling complex.

8 ransduction and that they may form part of a signaling complex.

9 on of signaling coordinated through the TAK1 signaling complex.

10 n of Wnt signaling by an AQP1-macromolecular signaling complex.

11 unoprecipitates with components of the IFNAR signaling complex.

12 alian target of rapamycin complex 1 (mTORC1) signaling complex.

13 oylated EGFR, reducing formation of the PI3K signaling complex.

14 the trimolecular, HS-growth factor-receptor, signaling complex.

15 ved inhibitors that target the Elmo-Dock-Rac signaling complex.

16 the localization and function of the M1R/Gq signaling complex.

17 ing receptosome called the motility-inducing signaling complex.

18 mbly and activation of the Norrin-Fz4-Lrp5/6 signaling complex.

19 ellular Sema3a signals to the slit-diaphragm signaling complex.

20 cruitment of caspase-8 to the death-inducing signaling complex.

21 moreceptors and the CheA kinase in a ternary signaling complex.

22 ized aggregates ready to form death-inducing signaling complex.

23 the role of Grb2, a component of the SHPS-1 signaling complex.

24 s through the TCR is mediated by the TCR-CD3 signaling complex.

25 d function of Ste50 mutants in the pheromone-signaling complex.

26 TlpD that inactivates the chemotransduction signaling complex.

27 mposed of ZAP70-bound TCR and LAT-associated signaling complex.

28 PTPN6 (Shp1) phosphatase activity within the signaling complex.

29 nate antigen, CIN85 was recruited to the TCR signaling complex.

30 rk dependent Etv5/Satb2 chromatin repressive signaling complex.

31 high-resolution structure of this important signaling complex.

32 or signaling via degradation of the receptor-signaling complex.

33 n, CD3deltaepsilon, and zetazeta) of the TCR signaling complex.

34 rom binding and recruiting TbetaRI to form a signaling complex.

35 lization and trafficking of NHERF1 assembled signaling complexes.

36 AMP compartments and defining the functional signaling complexes.

37 inhibitor binding and restored fusion kinase signaling complexes.

38 a key structural component of receptor core signaling complexes.

39 imer packing and the kinase-ON state of core signaling complexes.

40 al to the formation and maintenance of these signaling complexes.

41 ions and facilitate the assembly of distinct signaling complexes.

42 lates its function via formation of distinct signaling complexes.

43 ts M1 and K63 chain formation in TLR induced signaling complexes.

44 ability to stabilize regulator of G protein signaling complexes.

45 ich assemble cognate kinases into productive signaling complexes.

46 ion forks to initiate assembly of checkpoint signaling complexes.

47 ulation, dynamics, and function of LAT-based signaling complexes.

48 T and intact Cav-3-associated macromolecular signaling complexes.

49 s to either the gB- or gH-generated receptor signaling complexes.

50 his allows for integration of receptors into signaling complexes.

51 ccessory protein, which precludes functional signaling complexes.

52 d as transient platforms for the assembly of signaling complexes.

53 ngaging Src from FAK-associated adhesion and signaling complexes.

54 formation or reduced stability of CD40L-CD40 signaling complexes.

55 ling activator, MALT1, which disrupted MALT1 signaling complexes.

56 PDZ recognition motifs to form multiprotein signaling complexes.

57 ity of the receptors themselves and of their signaling complexes.

58 mutations that alter the dynamic assembly of signaling complexes.

59 affold proteins used for assembling synaptic signaling complexes.

60 ly shifts the ON-OFF equilibrium of receptor signaling complexes.

61 signaling by tuning the content of CaV1.2 at signaling complexes.

62 apoptosis and necroptosis through different signaling complexes.

63 tors, phosphorylation of membrane-associated signaling complexes, activation of mitogen-activated pro

64 To dissect the GDNF-GFRalpha1-RET signaling complex, agents that bind and activate RET dir

65 This shared signaling complex allowed IL-33 to induce the EGFR-media

66 , suggesting specificity for the MDP-induced signaling complex and activator-dependent differences in

67 ndothelial growth factor receptor 2 (VEGFR2) signaling complex and attenuates vascular endothelial gr

68 assembly of an activated VEGFR2/GIV/Galphai3 signaling complex and enhancing downstream PI3K/Akt surv

69 strate that OGT-1 and EEL-1 form a conserved signaling complex and function together to affect GABA n

70 s, SPATA2 is recruited to the TNF receptor 1 signaling complex and is required for CYLD recruitment.

71 dings suggest that EFNB1 is part of the EGFR signaling complex and may mediate drug resistance in HNS

72 a suggest that CIN85 is recruited to the TCR signaling complex and mediates inhibition of T cell acti

73 ever, in contrast to WASp, WAVE2 leaves this signaling complex and migrates peripherally together wit

74 The nature of the TCR signaling complex and subunit arrangement in different s

75 a component of the FER-regulated RHO GTPase signaling complex and that fer and llg1 mutants display

76 d are based on structural information of the signaling complex and the dynamics of the underlying bio

77 ed association of SHP-1 with the VEGFR2/CD36 signaling complex and thereby suppressed VEGFR2 phosphor

78 thematically modeled TRAF1.NIK as a coupling signaling complex and validated computational inference

79 phase separation occurs within a variety of signaling complexes and cellular structures.

80 ludens-1 adapter that acts as a scaffold for signaling complexes and cytoskeletal-plasma membrane int

81 that TRIM5alpha can form both well-organized signaling complexes and nonsignaling aggregates, 2) offe

82 the structure and function of core receptor signaling complexes and the architecture of higher-order

83 4, revealed the known core mTORC1 regulatory signaling complexes and the intimate interplay of the mT

84 mes, act as scaffolds to control assembly of signaling complexes and their localization, serve as mol

85 tions are shaped by a balance among opposing signaling complexes and transcription factors competing

86 ta more efficiently into active cell surface signaling complexes and triggered greater STAT1 and STAT

87 icking vesicles, is required to assemble DLK signaling complexes and, unexpectedly, is essential for

88 ically interacts with components of the Ras2 signaling complex, and a range of other signaling and cy

89 erize their upstream activators, assembly of signaling complexes, and activation of downstream signal

90 g of Girk channel structure, organization in signaling complexes, and plasticity, as well as progress

91 Our results suggest that changes in signaling complex architecture not only enhance the rate

92 he cell membrane and specifically to the TCR signaling complex are largely unknown.

93 Dynamic assembly/disassembly of signaling complexes are crucial for cellular functions.

94 (3FRET) technology, we demonstrate how WAVE2 signaling complexes are dynamically regulated during lym

95 he formation of an active ErbB2/PKCdelta/Src signaling complex, as depletion of PKCdelta disrupts ass

96 e mechanisms of nucleic acid recognition and signaling complex assembly involving the AIM2 (absent in

97 that PhoU is involved in the formation of a signaling complex at the cytoplasmic membrane that respo

98 The formation of a store-dependent signaling complex at the plasma membrane provides for se

99 Organization of signaling complexes at excitatory synapses by membrane-a

100 on the assembly of multiprotein adhesion or signaling complexes at particular subcellular sites.

101 uantify the coformation of multiprotein EGFR signaling complexes at the plasma membrane in response t

102 The assembly of signaling complexes at the plasma membrane is required f

103 Disruption of the Na/K-ATPase.c-Src signaling complex attenuated ouabain-stimulated protein

104 ligand, amphiregulin, for the formation of a signaling complex between T1/ST2 (the IL-33R) and EGFR.

105 and STAT5, failure to exclude SHP-1 from the signaling complex blunts their type I IFN response.

106 the cryo-EM structure of the human CB2-G(i) signaling complex bound to the agonist WIN 55,212-2.

107 re, we present the structure of the CB1-G(i) signaling complex bound to the highly potent agonist MDM

108 dy, we determined the topology of the T cell signaling complex by examining the respective relation o

109 Disruption of this signaling complex by knocking down PTK2, YWHAZ, or MED1

110 mation of discrete, localized multimolecular signaling complexes by A-kinase anchoring proteins.

111 MAD2 and the meiotic HORMADs, assemble into signaling complexes by binding short peptides termed "cl

112 PTPN22 stability versus translocation to TCR signaling complexes by CSK-dependent and CSK-independent

113 at RARgamma initiates the formation of death signaling complexes by mediating RIP1 dissociation from

114 c conformational changes in membrane protein signaling complexes by nuclear magnetic resonance (NMR)

115 Pharmacological enhancement of the mGlu5/eCB signaling complex, by positive allosteric modulation of

116 RP3 is a key component of the macromolecular signaling complex called the inflammasome that promotes

117 nous "danger" signals activate innate immune signaling complexes called inflammasomes to process IL-1

118 ters recruited two conserved furrow-inducing signaling complexes, chromosome passenger complex (CPC)

119 mation of membrane-anchored TNFR1-containing signaling complex (complex I), RIPK1 ubiquitination, and

120 FGF23 stimulates the assembly of a signaling complex composed of alpha-Klotho (KLA) and FGF

121 ibiting the formation of a poly(I:C)-induced signaling complex composed of TAK1, TAB1 (TAK1 binding p

122 ke and mTORC1 activation also required a TCR signaling complex composed of the scaffold protein CARMA

123 d protein kinase A (PKA) within an assembled signaling complex comprising pTyr-PAK1, Etk/Bmx, the het

124 We propose that membrane-proximal signaling complexes constrained by AKAP220 impact the ac

125 Core signaling complexes contain two trimers of transmembrane

126 y controlled assembly of a TGF-beta receptor signaling complex containing alpha3beta1 integrins, beta

127 s by promoting formation of a death-inducing signaling complex containing receptor-interacting serine

128 eability through association with a scaffold signaling complex containing ZO-2, Afadin, and the small

129 e association of individual molecules within signaling complexes containing ion channels (M-type K(+)

130 These two AKAP proteins form signaling complexes containing protein kinases A and C,

131 , and Stat6) and prevents the formation of a signaling complex (containing p38MAPK, PKCdelta, and Sta

132 , indicating CCM2 as the cornerstone for CCM signaling complex (CSC).

133 us suggests that activity of heteromeric NLR signaling complexes depends on the sum of activation pot

134 tor-mediated formation of the death-inducing signaling complex (DISC) and by the inflammasome adaptor

135 subsequent failure to induce Death-Inducing Signaling Complex (DISC) components, and decreased FasL

136 R5) leads to the formation of death inducing signaling complex (DISC) for apoptotic signaling.

137 The death-inducing signaling complex (DISC) initiates death receptor-induce

138 lustering and assembly of the death-inducing signaling complex (DISC), increasing caspase-8 activatio

139 rylation and formation of the death-inducing signaling complex (DISC).

140 ignaling proteins to form the death-inducing signaling complex (DISC).

141 nd TRADD and caspases to form death-inducing signaling complexes (DISC).

142 adaptor protein that nucleates the proximal signaling complex downstream of the TCR, were unable to

143 ndings suggest that SASH1 acts to assemble a signaling complex downstream of TLR4 to activate early e

144 Multi-molecular signaling complexes drive the earliest events of immune

145 ficking and/or the formation or recycling of signaling complexes during rhizobial and AMF symbiosis.

146 ith loss of the well-known downstream immune signaling complex ENHANCED DISEASE SUSCEPTIBILITY 1 (EDS

147 onical components of the CD95 death-inducing signaling complex, FADD and caspase-8, and on the activa

148 Additionally, PG102-induced CD40 signaling complexes failed to recruit TRAF6 to detergent

149 s induced the formation of dsDNA-Rad50-CARD9 signaling complexes for activation of the transcription

150 a major structural adaptor protein governing signaling complex formation and cytoskeletal dynamics.

151 tivation by soluble TWEAK impairs CD40L-CD40 signaling complex formation and inhibits CD40 signaling

152 with procaspase-8, inhibiting death-inducing signaling complex formation in response to Fas/Fas ligan

153 iquitin chains regulate protein scaffolding, signaling complex formation, and kinase activation, and

154 beta-activated kinase 1 (TAK1) mediates LMP1 signaling complex formation, NEMO ubiquitination and sub

155 to TbetaRIII competes with TbetaRI/TbetaRII signaling complex formation, thus inhibiting TGF-beta-me

156 m of cytokine capable to disrupt gp130/IL11R signaling complex formation, thus serving as a high-affi

157 egradation and decreased EGFR/Grb2/Shp2/Gab1 signaling complex formation.

158 s regarding the supramolecular nature of the signaling complex formed by receptor and G protein.

159 Finally, affinity of PDE10A to the signaling complexes formed around AKAP150 was reduced by

160 the more primitive ancestral form of the TCR signaling complex found in chickens.

161 erefore, it is possible that the NR2A/PSD-95 signaling complex has a role in adolescent MS effects.

162 oughs in resolving the 3D structures of eFGF signaling complexes have now unveiled the atomic details

163 Reconstitution of the IL7 receptor signaling complex in 293T cells showed that JAK3 mutants

164 ryophytes, we evaluated the presence of this signaling complex in a charophyte green alga, Chara brau

165 alpha like (GFRAL)-Ret proto-oncogene (RET) signaling complex in brainstem neurons that mediates GDF

166 nexpectedly need ALK6 as a coreceptor in the signaling complex in granulosa cells.

167 he formation of a preassembled TLR-Myddosome signaling complex in steady-state DCs but not macrophage

168 eromer and challenge the existence of such a signaling complex in the adult animals that we used for

169 e reconstituted a complete chemotransduction signaling complex in vitro with TlpD and the chemotaxis

170 TOR is found in two distinct signaling complexes in cells, TOR complex 1 (TORC1) and

171 l sequences of partner proteins and assemble signaling complexes in multicellular organisms.

172 to recruit FSN-1 and RAE-1 into independent signaling complexes in neurons.

173 and promotes the formation of innate immune signaling complexes in response to nucleic acid sensing

174 ted specifically in alpha6 integrin receptor signaling complexes in the lens equatorial region, where

175 ponents of the N-methyl-D-aspartate receptor signaling complex, including the PSD-95 complex, activit

176 Here we report a novel endosome-based signaling complex induced by MACs to stabilize NIK.

177 c receptor that is proximal to the Myddosome signaling complex, inducing IRAK4 kinase domain dimeriza

178 ocation of alpha5beta1 integrin-acylated Fyn signaling complexes into lipid rafts upon uPAR ligation

179 eveal how SAP nucleates a previously unknown signaling complex involving NTB-A and LCK to potentiate

180 prisingly, we found that 2 types of proximal signaling complexes involving SLP-76 were formed.

181 roviding insights into how this multiprotein signaling complex is assembled and functions via multiva

182 the phagosome, indicating that the TLR-MyD88 signaling complex is assembled at a prelysosomal stage a

183 mammals, the alphabetaT cell receptor (TCR) signaling complex is composed of a TCRalphabeta heterodi

184 The IL-6 signaling complex is described as a hexamer, formed by t

185 imic a cell-cell junction, we found that the signaling complex is not efficiently internalized when l

186 affinity, but how sENG participates in BMP9 signaling complexes is not fully resolved.

187 ns that controls the coordinated assembly of signaling complexes, is regulated by phosphorylation of

188 an promote dynamic assembly of multi-protein signaling complexes, lead to intracellular liquid-liquid

189 phosphorylate DCC and form a receptor-bound signaling complex leading to activation of downstream ef

190 levels but also recruits IQGAP1 into the Wnt signaling complex, leading to potent and robust potentia

191 on reactions that recruited NEMO to the MAVS signaling complex, leading to the activation of IKK and

192 0 suggesting the existence of a multiprotein signaling complex localizing PDE10A to a specific functi

193 of RecA rapidly nucleates to form early SOS-signaling complexes, maturing into DNA-bound RecA bundle

194 tes different environmental cues via the two signaling complexes mTOR complex 1 (mTORC1) and mTORC2.

195 amycin (mTOR) kinase forms two multi-protein signaling complexes, mTORC1 and mTORC2, which are master

196 neage kinase domain-like pseudokinase (MLKL) signaling complex (necrosome) that we find compartmental

197 ad2/3 signaling or binds ACVR1 to form a non-signaling complex (NSC).

198 l summarize current views on the assembly of signaling complexes nucleated by LAT.

199 four ligands, indicating that activation of signaling complexes occurs after endocytosis.

200 esults define the functional properties of a signaling complex of CaMKII and Ca(V)2.1 channels in whi

201 tt may lead to formation of a death-inducing signaling complex of Hip1, Hippi, and Caspase-8.

202 localization of RhoA and the formation of a signaling complex of RhoA/ROCK2/myosin phosphatase-targe

203 cuous, while their clustering into nanoscale signaling complexes on the plasma membrane, termed nanoc

204 ling cascades coalesce into large oligomeric signaling complexes, or signalosomes, for signal propaga

205 In this study, we show that the TWEAK/Fn14 signaling complex plays a protective role during the acu

206 and attenuated signaling via the pre-B cell signaling complex (pre-BCR) and the differentiation of p

207 ion of insulin-like growth factor 1 receptor signaling complexes present in perinuclear invaginations

208 d OFF signaling states, suggesting that core signaling complexes produce kinase activity over a range

209 detailed molecular insight into the Ras-PI3K signaling complex, provide a framework for screening Ras

210 ient activation of Src and p38 in a specific signaling complex, providing a tool for targeted regulat

211 Notably, these perinuclear signaling complexes (PSC) are present in tumor cell line

212 kinase anchoring protein 79/150 (AKAP79/150) signaling complex regulates excitatory synaptic transmis

213 Taken together, a Sema3A-initiated apoptotic signaling complex regulates the apoptosis of sympathetic

214 dermal growth factor receptor (EGFR) forms a signaling complex regulating epidermal homeostasis.

215 atform for the assembly of the mitochondrial signaling complex required for maximal activation of RIG

216 UBAC components as interacting with the TLR3-signaling complex (SC), thereby enabling TLR3-mediated g

217 ular signals are often transduced by dynamic signaling complexes ("signalosomes") assembled by oligom

218 We conclude that this is a signaling complex specialized for sensing adhesion under

219 this inhibitor reveal the critical nexus of signaling complex stability in the regulation of NF-kapp

220 ned that the mitochondria-localized PKCdelta signaling complex stimulates the conversion of pyruvate

221 are important in the assembly of oligomeric signaling complexes such as the PIDDosome that acts as a

222 n of autophagy requires several multiprotein signaling complexes, such as the ULK1 kinase complex and

223 ift in EGFR dimerization partners within the signaling complex, suggesting that targeted drugs may tr

224 proteins were components of cell junctional signaling complexes, suggesting that additional potentia

225 ly regulate the assembly of a macromolecular signaling complex termed the necrosome.

226 teracting with FN and enhancing beta-catenin signaling, complexed TG2 stimulates OC cell proliferatio

227 and TANK-binding kinase 1 (TBK1), to form a signaling complex that activates IFN regulatory factor 3

228 au, thereby contributing to recruitment of a signaling complex that amplified downstream signals and

229 PG102 induced the formation of a CD40 signaling complex that contained decreased amounts of bo

230 f several amino acids when in a multiprotein signaling complex that contains regulatory-associated pr

231 ssembly of the channel with AKAP79 to form a signaling complex that couples Orai1 channel function to

232 ause it participates in a membrane-delimited signaling complex that forms after store depletion and b

233 Unlike IL-1beta, IL-33 does not have a signaling complex that includes both its cognate recepto

234 odendrocyte cells induced the formation of a signaling complex that includes the AMPA receptor, integ

235 re: 1) NHE3 basal activity is regulated by a signaling complex that is controlled by sequential effec

236 as-GTP in live cells, resulting in a ternary signaling complex that is further regulated by GPCRs.

237 ave identified a membrane structure and Ca2+-signaling complex that may enhance the speed of atrial c

238 These proteins formed a signaling complex that mediates these oncogenic processe

239 kinase C (PKC)epsilon to the downstream TLR-signaling complex that translocated PKCepsilon into the

240 omologous recombination and also assembly of signaling complexes that activate the DNA damage checkpo

241 Inflammasomes are intracellular signaling complexes that are assembled in response to a

242 hat TLR4 induces assembly of caspase-8-based signaling complexes that become licensed as IL-1beta-con

243 s, caspases are activated via macromolecular signaling complexes that bring inactive procaspases toge

244 Targeting of signaling complexes that contain select kinase isoforms

245 Inflammasomes are large macromolecular signaling complexes that control the proteolytic activat

246 ) elicits the spatiotemporal assembly of two signaling complexes that coordinate the balance between

247 try to biochemically characterize endogenous signaling complexes that function downstream of IL-17 re

248 rticipate in the formation of macromolecular signaling complexes that include protein kinases, ion ch

249 TNFR1 forms distinct signaling complexes that initiate gene expression progra

250 Inflammasomes are oligomeric signaling complexes that promote caspase activation and

251 ssory and transmembrane proteins assemble in signaling complexes that sense and integrate multiple si

252 Bacterial chemotaxis is mediated by signaling complexes that sense chemical gradients and di

253 lipidated microbial products to various TLR signaling complexes that subsequently induce intracellul

254 Inflammasomes are multiprotein signaling complexes that ultimately lead to caspase acti

255 fic in vivo cross-linking assays, and formed signaling complexes that were dispersed around the cell

256 FNAR1 is an essential component of the IFNAR signaling complex, the key residues underpinning the IFN

257 Moreover, analogous to the human TCR signaling complex, the presence of two copies of CD3epsi

258 ytoskeleton, supporting the formation of the signaling complex, the signalosome, on the IL-7 receptor

259 LGR4 with IQGAP1 brings RSPO-LGR4 to the Wnt signaling complex through enhanced IQGAP1-DVL interactio

260 ay regulate degradation of the IL-4 receptor-signaling complex through interactions with NEDD4.2.

261 necrosis factor alpha (TNFalpha) receptor 1 signaling complex (TNF-RSC) and attenuates TNFalpha-indu

262 NFalpha leads to the formation of the TNF-R1 signaling complex (TNF-RSC) to mediate downstream cellul

263 motif functions to recruit NFAT to the LTCC signaling complex to promote its activation by AKAP-anch

264 However, the relevance of this signaling complex to the long-term consequences of traum

265 bsequent retrograde translocation of the JNK signaling complex to the nucleus.

266 tubule (DCT), potassium imbalance causes WNK signaling complexes to concentrate into large discrete f

267 nsplanted cells deliver activated Wnt7a/Fzd7 signaling complexes to recipient myofibers.

268 ectors, and other key proteins form specific signaling complexes to regulate specific cell responses

269 e cytoskeletal protein talin assemble into a signaling complex upon E-cadherin loss.

270 romoted the formation of hERG/beta1-integrin signaling complexes upon extracellular matrix stimulatio

271 characterization of the assembly of the FGF signaling complex using isothermal titration calorimetry

272 ttling factor that nucleates the assembly of signaling complexes using a bilayered mechanism of phosp

273 h the controlled assembly and disassembly of signaling complexes using a stereotypical "safety belt"

274 t of light makes visualization of individual signaling complexes using visible light extremely diffic

275 /beta-arrestin-1(beta-arr1) membrane protein signaling complex, using only 5 muM protein and 20 min o

276 tion between ARGOS and the ethylene receptor signaling complex via AtRTE1 and maize RTL proteins, sup

277 Assembly of active signaling complexes was confirmed by immunostaining of p

278 , and IGF-I facilitated its recruitment to a signaling complex where it oxidized src, leading to AKT

279 cruited to the T cell antigen receptor (TCR) signaling complex, where it reversed inhibitory phosphor

280 and endogenous formation of a death-inducing signaling complex which activated caspase-8.

281 lizes beta-catenin through the LRP6 receptor signaling complex, which antagonizes the beta-catenin de

282 sforming growth factor-beta (TGFbeta) family signaling complex, which is highly expressed on endothel

283 The inflammasome is an intracellular signaling complex, which on recognition of pathogens and

284 that the GABAB receptor forms part of larger signaling complexes, which enable the receptor to mediat

285 PAS domains are in contact and form the core signaling complex, while the alpha1 H-NOX domain can be

286 e we report a cryo-EM structure of FPR2-G(i) signaling complex with a peptide agonist.

287 ng Gbetagamma and PLCbeta but still formed a signaling complex with Gbetagamma and PLCbeta2 probably

288 ells and in focal adhesion, where it forms a signaling complex with PAK2 and paxillin in response to

289 ta (PKCeta) forms a novel (to our knowledge) signaling complex with the checkpoint inhibitory protein

290 GPR161 forms a signaling complex with the scaffold proteins beta-arrest

291 phrin phosphorylation through formation of a signaling complex with the Src family kinase Fyn.

292 eta superfamily, is a homodimer that forms a signaling complex with two type I and two type II recept

293 Formation of signaling complexes with arrestins often requires recrui

294 n sulfate as a coreceptor in the assembly of signaling complexes with FGF-receptors on the plasma mem

295 TRPC1 channels and MARCKS form signaling complexes with PI(4,5)P2 bound to MARCKS; in t

296 could form functional heterodimeric receptor signaling complexes with the synthetic IL-6 receptor cha

297 ystem (CNS), Homer scaffolding proteins form signaling complexes with two CaSR-related members of the

298 12Rbeta1) as one component of their receptor signaling complexes, with IL-12Rbeta2 as second receptor

299 nraveling the spatiotemporal organization of signaling complexes within the context of plasma membran

300 ustering and formation of the death-inducing signaling complex, yet the underlying regulatory mechani