ライフサイエンスコーパス: significant

1 Broome and Tioga counties were 0.93 and not significant.

2 The difference was not statistically significant.

3 early onset (EO), lethal, and/or clinically significant.

4 ynthesis make the synthetic model viable and significant.

5 sugrel and ticagrelor were not statistically significant.

6 from baseline for all other scales were not significant.

7 growth of B. subtilis does not result in the significant accumulation of extracellular D-alanine.

8 iated with frequent AECRS with statistically significant adjusted odds ratios (aORs) after controllin

9 ty versus ion pump inhibition by ouabain), a significant advance against state of the art cell based

10 While significant advancements have been made in cancer therap

11 Significant advancements have occurred in the ability to

12 EoE) has received the most focus, leading to significant advances in understanding of disease mechani

13 bility of bacteria within 15 min, which is a significant advantage over existing techniques that cons

14 .0%; full professor 13.0% vs 37.2%) were not significant after adjusting for career duration (P = .08

15 These effects remained significant after excluding nonrandomized trials, or tri

16 ion Whole-body diffusion-weighted MRI showed significant agreement with fluorine 18 fluorodeoxyglucos

17 , our transcriptomics analyses also revealed significant alterations in gene expression levels of key

18 .001), and %HEX increased by a statistically significant amount (0.7%, P = 0.030) in the timolol grou

19 The results also identify a significant amount of cell-associated Hg-S(3)/S(4) speci

20 bis(benzofuran-3(2H))-one) (D2), obtained in significant amounts, that were characterized by means of

21 anti-ZIKV T-cell response without eliciting significant anti-ZIKV antibodies, while vaccination with

22 ultivariable adjusted analyses, there was no significant association between baseline eGFR <60 ml/min

23 Results showed a significant association between cord serum interleukin-7

24 There was no significant association between donor MDRO and either me

25 There was no significant association between the duration of mTOR inh

26 d biological variables fails to identify the significant association for walleye pollock, and (d) cod

27 usting for other shared risk factors, with a significant association remaining only for ACR (>=103 co

28 No significant association was noted between VL, admission

29 No significant association was observed between fundus abno

30 two procedures should be weighed against its significant association with postoperative underaction o

31 The authors identified novel genome-wide significant associations near genes involved with global

32 were inversely associated with ICH risk, no significant associations were found for HDL and triglyce

33 Adjusting for mental disorders, three significant associations, all on chromosome 20, were ide

34 The TB/DM association was significant at enrollment in both new and preexisting DM

35 Decarboxylation rates were significant at low light (including above the Kok break

36 eover, nanoscaffold-based approaches promote significant axonal growth and functional recovery in viv

37 Presenteeism in nursing is particularly significant because it puts patients at risk by reducing

38 Darolutamide was also associated with a significant benefit with respect to all other secondary

39 Phase III adjuvant trials have reported significant benefits in both relapse-free survival (RFS)

40 Overall, there were no statistically significant benefits of any intervention individually or

41 There were no significant benefits of medication on likelihood of smok

42 There were no significant between-group differences in both worst and

43 No significant between-group differences were found for any

44 Significant biases for maternal alleles were detected on

45 canism-driven environmental change triggered significant biogeochemical changes, and cascaded organic

46 iously disabling psychiatric disorder with a significant burden of disease.

47 dentify 48 genes (25 newly reported) showing significant burden of ultra-rare (MAF < 0.01%) gene-disr

48 ect effects of warming on VOC emissions were significant but smaller than the direct effects, during

49 enditures than site COC did, which indicated significant care coordination gaps within the same facil

50 Significant carriage of these serotypes remains in all a

51 Invasive pulmonary aspergillosis (IPA) is a significant cause of morbidity and mortality in lung tra

52 Actuation remains a significant challenge in soft robotics.

53 d availability of purified GSLs represents a significant challenge to the discovery and characterizat

54 nces for a conformational ensemble remains a significant challenge.

55 n barrier of ambient electrochemical NRR are significant challenges, making a simultaneous high NH(3)

56 ion, identified 102 metabolic reactions with significant change in flux in MG1655:: tetA when grown i

57 er a 53 year period from 1962 to 2015 and no significant change in Pseudoterranova spp. abundance ove

58 A significant change in the lipid-packing order takes plac

59 There were no significant changes about lung function test, smoking hi

60 Both behaviours showed significant changes as the temperature increased.

61 Ts) decreased significantly post-PCV, but no significant changes occurred in persons >=5 years of age

62 Significant changes of cerebrospinal fluid microRNAs tha

63 ormed at different times over 24 h, revealed significant changes only for RNA-binding motif 3 (Rbm3).

64 We identified significant clinical differences but also identified imp

65 noclonal antibodies (mAbs) have demonstrated significant clinical efficacy, there is also the potenti

66 A significant contribution from the Bayesian method was re

67 ecticide usage is consistently proposed as a significant contributor, among other threats.

68 hat only females and not males show a highly significant correlation between an increase in TARP and

69 hroat swabbing and establish a statistically significant correlation between the detected level of hu

70 We obtained significant correlations between brain structure and mar

71 demonstrate that the biomarkers do not show significant daily variation, and that they are stable fo

72 A significant decrease in phosphorylation of signal transd

73 This configuration allows a significant decrease of the uranium polyatomic interfere

74 es, and Corynebacterium, while others showed significant decreases (e.g., Alloprevotella and Capnocyt

75 s, plasma membrane-associated tubulin showed significant decreases in acetylation from depressed suic

76 h-virulence strain of C. difficile; however, significant deficits in intestinal neutrophils and eosin

77 Facile chemical treatments provide a significant degree of flexibility to tailor microbial me

78 Further, obstetrical injury has significant deleterious impact on recovery of the vagina

79 l that micro-structured tungsten can exhibit significant deviation from the blackbody spectrum.

80 GR than control foetuses, while there was no significant difference among IUGR groups.

81 h was 7.40 +/- 3.39 mm, with a statistically significant difference between dentate and edentulous qu

82 dary end points, none showed a statistically significant difference between groups, including in-hosp

83 No significant difference between Mirococept at 10 mg and c

84 pled plasma mass spectrometric method and no significant difference between the results was observed.

85 justed MSPHM survival analyses also found no significant difference in 28-day survival for cases trea

86 ese energetic changes such that there was no significant difference in comparison with controls.

87 l and generic PGAs did not show a clinically significant difference in IOP-lowering effect or tolerab

88 e hospital admission, and intubation, but no significant difference in quality of life.

89 There was no statistically significant difference in readmission rates.

90 izes (Cohen's d = 0.8-0.9), but there was no significant difference in the hippocampus.

91 No significant difference in the risk of cardiovascular dea

92 No significant difference was observed in the 3-year incide

93 Similarly, there was no significant difference within different types of glaucom

94 The statistical analysis showed significant differences between genotypes and pollinatio

95 ng affinity than (Hs)CRM1 toward PKI-NES and significant differences in affinities toward potential C

96 There were significant differences in body size, blood pressure, an

97 Significant differences in CTRP1 levels were discovered

98 We did not find significant differences in fecal microbiota composition

99 We observe significant differences in gut microbiome composition ac

100 However, there were no statistically significant differences in handgrip strength, delirium r

101 llected at 7-12 months post-injury showed no significant differences in lesion size, fibrotic scar, g

102 There were no significant differences in measures of mitochondrial res

103 ; however, orthopedics outcomes did not show significant differences in mortality across teaching and

104 There were significant differences in Raman features corresponding

105 Metagenomic analysis did not reveal significant differences in taxonomic or functional pathw

106 We detected significant differences in the protein decoration of sEV

107 use of glyphosate-based herbicides can cause significant differences in wheat protein chemistry and s

108 of the treatment group, but no statistically significant differences were detected.

109 perature had a small effect on recovery, but significant differences were observed for phlorizin and

110 No significant differences were seen between the other symp

111 Genes showing significant differential expression (log2FC >= 1, Padj <

112 Acquired hospitals had a significant differential improvement in performance on t

113 0-minute cutoff did not reveal evidence of a significant discontinuity (P=0.66).

114 There is significant discordance in the determination of SSIs rep

115 e surveillance, identification of clinically significant disease, choice of postprostatectomy adjuvan

116 Significant down-regulation of terminal differentiation

117 n of either, or both, isoform(s) was without significant effect on either the frequency, amplitude, o

118 We conclude that "Sweating'' has significant effect on metabolites content and compositio

119 al comparisons of K(i) and K(i) change found significant effects of Parkinson disease.

120 al, -.14 to -.02]), but had no statistically significant effects on bacteria, viruses, or the prevale

121 lorophenyl)ethenyl]-1H-pyrazole 2l 1) caused significant effects on the cell cycle in PC3 cells, with

122 -hoc analyses demonstrated that patients had significant enlargement of lateral ventricles (F(1,59) =

123 F(ST) scans and PCAdapt, which represents a significant enrichment.

124 destroyed within a few months, resulting in significant environmental and economic losses.

125 s in domestic-use groundwater aquifers poses significant environmental and human health concerns.

126 c stress caused by drought and salinity is a significant environmental threat that limits plant growt

127 Incidence is high, with significant ethnic and socioeconomic variation.

128 lidation, helping to ensure that emotionally significant events are well remembered.

129 Since then, significant evidence has emerged to support the etiologi

130 Conversely, we find no statistically significant evidence of a higher false discovery rate, o

131 Overall, we identified a significant excess of loss-of-function DNMs in genes hig

132 eaction on metal-oxide photoanodes remains a significant experimental and theoretical challenge.

133 how no evidence of population structure (non-significant F(ST) < 0.001) for M. alfredi along this coa

134 ithin groups, CV declined in a statistically significant fashion from baseline to month 3 in all 3 gr

135 tus in patients on hemodialysis, but have no significant favorable effect on VC progression.

136 ane at 3 months postoperatively was the only significant feature correlated with postoperative BCVA a

137 immune privileged sites, these findings are significant for future investigations of filovirus patho

138 bles, (b) physical drivers are statistically significant for Pacific cod and walleye pollock recruitm

139 These observations are significant for purification and formulation of rNDV, as

140 easingly marginal for production, but highly significant for wildlife, and suggest that such tradeoff

141 Finally, we demonstrate that a significant fraction of PSVs in segmental duplications o

142 ial to serve as a matchmaking RNA chaperone, significant gaps remain in our understanding of the mole

143 ty-three percent of patients have died, with significant geographic variability, ranging from 27% to

144 Secondary endpoints did not reveal any significant group differences.

145 d by frequent acute exacerbations leading to significant health care burden and impaired quality of l

146 Food allergies have become a significant heath burden as prevalence continues to rise

147 of the population globally however there is significant heterogeneity in existing epidemiological st

148 ith severe ptosis, there was a statistically significant higher rate of success after MMCR (P = .0143

149 SPECT/CT and basic fuchsin staining revealed significant higher-density spatial accumulation of linea

150 a low dose of 25 ug/kg (p.o.) did not induce significant hyperactivity itself, but significantly pote

151 ing feature-tracking strain assessment has a significant impact on the results.

152 D, while 107 (3.0%) had GERD associated with significant impairment of quality of life.

153 inding by HPV E7 impairs differentiation has significant implications for HPV-mediated carcinogenesis

154 than traditional centrality measures and has significant implications for network-based interventions

155 These findings have significant implications for understanding why a hypomor

156 recombination and local linkage brings about significant improvement in the inference of natural sele

157 (accuracy > 84% for predicting statistically significant improvements in patient outcomes for 26 firs

158 Statistically significant improvements were seen in the POST period fo

159 eration to viral persistence is particularly significant in T(EM) cells.

160 ta and South Dakota, and an upward trend was significant in Texas and the western part of the Great P

161 ver time in reported cough was statistically significant in the children residing in the azithromycin

162 porally, an overall decrease in the HDWs was significant in the eastern regions of North Dakota and S

163 These results remained significant in the subgroup analysis of small aneurysms

164 eiving placebo, and it was associated with a significant increase in plasma glucagon and a decrease i

165 There was a statistically significant increase in the relative composition of CD14

166 A significant increase was found in eye drop instillation

167 as associated with a small but statistically significant increased risk of major surgical complicatio

168 st hoc analysis, there were no statistically significant increases from week 52 to week 130 in either

169 nificant increases in maternal lead and with significant increases in cord blood lead and cadmium.

170 Though there were no statistically significant increases in KS rates in any demographic or

171 ltichannel membranes also show statistically significant increases, with temperatures that are consis

172 atistical analysis, we found that there were significant increasing trends (p <= 0.05) in annual prec

173 0.013) than the lowest quintile, which were significant independently after accounting for a recent

174 not train where CM is frequent, resulting in significant inertia to change.

175 The material imparts significant influence on the kinetics and thermodynamics

176 nd revealed the presence of metabolites with significant influence on the self-incompatibility reacti

177 T) cell loss in chronic HIV-1 infection is a significant insult to antimicrobial immune defenses.

178 Strong significant inter-hospital variation remained after adju

179 EV(1)% change (P <= 0.05) and 15 miRNAs with significant interaction (P <= 0.05) to ICS versus placeb

180 Furthermore, the TPH2 genotype showed a significant interaction with childhood trauma in predict

181 noted within both groups (P < 0.05) without significant intergroup differences.

182 Observations of a significant kinetic isotope effect (k(H) /k(D) =5.7) for

183 9 distinct drug exposures with statistically significant, large relative risks indicating that cases

184 A significant limitation of standard MRI sequences is that

185 sed on the number of independent genome-wide-significant loci across all diseases (for example, 690 l

186 e CNV breakpoint association showed not only significant loci for genetic generalized and development

187 hat crystallizes in the comb, representing a significant loss to apiarists.

188 re intensive induction was associated with a significant lowering of ACR risk, particularly during th

189 EOC MCAs displayed significant LPA-induced changes in surface ultrastructur

190 related to nausea and vomiting, headache and significant malaise.

191 ny of the automated algorithms still require significant manual interventions or have yet to demonstr

192 Significant marginal bone loss occurred in the early pos

193 bility that the nuclear envelope may balance significant mechanical stresses in yeast and in cells fr

194 Tau PET was a significant mediator CBF/sPDGFRbeta-MoCA relationships i

195 efforts.IMPORTANCE Ebola outbreaks result in significant morbidity and mortality in affected countrie

196 progress to severe infection associated with significant morbidity and mortality.

197 ression regimens and allograft failure cause significant morbidity and mortality.

198 5-0.92]), whereas there was no statistically significant mortality reduction with prasugrel (HR, 0.90

199 function led to changes in expression for a significant number of genes involved in N signalling and

200 the external quantum efficiency spectra of a significant number of organic semiconductor blends.

201 A significant number of systematic reviews (SRs) and meta-

202 The association with AF was more significant (odds ratio, 6.15, P=3.26x10(-14)) when rest

203 on day 1 and in-hospital mortality remained significant (odds ratios, 1.29 and 1.26, respectively).

204 RETeval recordings identified significant OP implicit time delays in individuals with

205 by leading investigators with an emphasis on significant open questions.

206 verage NDVI and APOE epsilon4 status was not significant (OR: 1.04, 95% CI: 0.97, 1.11).

207 No significant (P < .01) covariates remained after backward

208 Cutoffs resulting in statistically significant (P < 0.005) differences between benign and m

209 ical health problems) remained statistically significant (P < 0.01).

210 decline between the 2 treatment arms was not significant (P = .09).

211 but this relationship was not statistically significant (P = .61).

212 ic time and alteplase dose was statistically significant (p = 0.018).

213 The difference was not statistically significant (p = 0.183).

214 g ischemia, the mortality difference was not significant; paclitaxel (12.8%) versus nonpaclitaxel dev

215 e rate (TRG1 = 8%) but was associated with a significant pathological regression (TRG1-2 = 44% vs 8%,

216 Together, these results show a significant physiological impact of amylin/calcitonin si

217 ed from 0.49 to 1.60 mg/kg w.w. and showed a significant positive relationship with the size and age.

218 efore, this proof-of-concept technique shows significant potential for highly sensitive quantitative

219 istinct modes with minimal interference, and significant power can be transmitted over long distances

220 itive results, a previous study identified a significant practical challenge regarding the co-alignme

221 This model obtains significant predictive power (AUC = 0.841).

222 istic regression) only Ultrasound depth is a significant predictor (p = 0.044) of a histologically no

223 and the use of primary prophylaxis were not significant predictors of HO-CDI.

224 ever, patient height and height squared were significant predictors of psoas area (P = .014 and P < .

225 Significant progress has been made following the 2011 re

226 Despite the significant progress in prediction algorithms, the funda

227 advances in molecular techniques have led to significant progress in the elucidation of the role of b

228 Altogether, flavonoids could have significant prophylactic value for retinal degenerative

229 A significant proportion of breast cancer patients develop

230 CVD affects a significant proportion of the population globally howeve

231 As such, while all treatments depleted a significant proportion of Tregs, the side effects in the

232 This trial did not identify a significant protective effect and was not designed to ev

233 However, in some patients SRL may cause significant proteinuria.

234 read of COVID-19 represents perhaps the most significant public health emergency in a century.

235 isease (COVID-19) in the United States, with significant public health implications.

236 Low-dose CT enabled significant radiation dose reduction.

237 CDKL5 promoter using three guide RNAs causes significant reactivation of the inactive allele in combi

238 The reconstruction represents a significant reactome expansion over available reconstruc

239 the DUBmut-infected mice had a statistically significant reduction (P < 0.05) in viral titer in liver

240 nary Disease Treatment) trial demonstrated a significant reduction in all-cause mortality (ACM) risk

241 The ancillary advantage would be a significant reduction in India's future power sector rel

242 a murine colitis model expressing hPXR by a significant reduction in inflammation biomarkers.

243 Furthermore, treatment was associated with a significant reduction in NT-proBNP and cTnI, suggesting

244 of posttax time points showed statistically significant reductions (-203.7 ounces, 95% CI: -399.6, -

245 95% CI, 0.80-1.06]) but were associated with significant reductions in total myocardial infarction (H

246 (44.6% vs. 46.6%), 8 diabetes remitters had significant reductions in WBC and platelet counts wherea

247 There remain significant regional disparities in the management and o

248 Amidst significant regional variations in COVID-19, lung transp

249 d 16 (44.4%) participants using both OAs had significant REI reductions.

250 We demonstrated that there is a significant relationship between infection of stomach wi

251 ped a final multivariate model with a highly significant relationship to UOC (Receiver operating char

252 nattention, the present study did not find a significant relationship with Autism Spectrum Disorder.

253 phological variants, and CNVs, statistically significant relationships were found with ASD and ADHD d

254 i.e., poor sensitivity and delayed results), significant research has been conducted to identify seps

255 female) were identified to have a clinically significant retrocorneal membranes at the time of graft

256 Metabolic syndrome is a significant risk factor for several common cancers (e.g.

257 Statistically significant risk factors for developing colon pathology

258 of retinoblastoma has been associated with a significant risk for recurrence, extraocular spread, and

259 The tumor microenvironment (TME) plays a significant role in cancer progression and thus modeling

260 vidence suggests that genetic factors play a significant role in completed suicide.

261 atanista gangetica gangetica), which plays a significant role in maintaining the structure, functions

262 ion of the primary motor cortex (M1) plays a significant role in mediating its therapeutic effects.

263 ies reveal that the region D1 in p27 plays a significant role in mediating the association kinetics,

264 ral cavity, and although they may not play a significant role in microbiome communities, they could s

265 lymphatic smooth muscle, they do not play a significant role in modulating the frequency of the ioni

266 on cover and water body availability, play a significant role in modulating the probability of a bird

267 R-155, suggested that microRNAs might play a significant role in regulation of PRF expression.

268 Selective sweeps are thought to play a significant role in shaping patterns of variability acro

269 selective shifts are likely to have played a significant role in the emergence of human-specific capa

270 Overall, there is still significant room for development in macrophage-mediated

271 litates real-time detection of statistically significant Rt changes, inference is highly sensitive to

272 A significant SB was observed for all MELD and DQI sub-gro

273 Both hexachlorophene and bithionol exhibited significant selectivity for Nape-pld compared with nonta

274 (1)H(alpha)-detect experiments, showing that significant sensitivity gains are achieved via proton de

275 Viral infection underlies a significant share of the global cancer burden.

276 cations requiring critical care that induced significant short- and long-term mortality.

277 ative ranges, with 15-47% of loci exhibiting significant signatures of balancing selection.

278 elatively high sequencing coverage to detect significant single nucleotide polymorphism (SNP)-trait a

279 t respond to environmental cues represents a significant step forward in the development of synthetic

280 The DFT model suggested significant surface restructuring of the TiO(2) support

281 Relative to NN, LN and HN showed more significant surface trends and spatial structures in SOC

282 Plant-parasitic nematodes pose a significant threat to agriculture causing annual yield l

283 Pathogens pose significant threats to pollinator health and food securi

284 on and emphysema phenotypes in subjects with significant tobacco smoke exposure using deep gene reseq

285 In xenografts, a significant tumor growth inhibition was seen after twice

286 pairwise comparisons yielding statistically significant values (P < .001).

287 al robotic credentialing policies identified significant variability and determined current policies

288 Significant variables associated with the occurrence of

289 for trend test <0.0001); however, there was significant variation in rates across hospital sites (ad

290 these biotic and abiotic factors resulted in significant variation in total plant mass, diaspore mass

291 No statistically significant variation was found for perinatal mortality.

292 rmed in 2014 and 2015 showed that there were significant variations (p < 0.001) for all assessed quan

293 The results indicated that significant variations existed in life cycle GWP, EU, an

294 We found significant VE against vaccine-type CIN2+ after 3 doses

295 + after 3 doses of HPV vaccine and lower but significant VE with 1 or 2 doses.

296 Binding is concomitant with a significant wavelength shift and an enhancement of the l

297 This study adds significant weight to the growing body of evidence in th

298 hology and mortality to livestock leading to significant welfare and socio-economic issues, predomina

299 ibution from the metagenome sequence data is significant with P-values less than 4.04E-17.

300 llin-Cre, female mice remain healthy despite significant X-autosome dosage imbalance.