ライフサイエンスコーパス: silylated

1 ortho-substituted aryl halides failed to be silylated.

2 to 1, none of its three uranyl fragments are silylated.

3 t facile cyclization/hydrosilylation to form silylated 1,2-dialkylidene cyclopentanes as mixtures of

4 The silylated 1,2-dialkylidenecyclopentanes formed via diyne

5 sequence provides both synthetically useful silylated 1,3-diene building blocks and insights into th

6 s, and provides very high yields of the beta-silylated 1,4-addition products.

7 ctive glycosylation of protected ribose with silylated 4(5)-haloimidazoles produces 5-haloimidazole r

8 entose sugar derivatives were condensed with silylated 4-amino-5-oxopyrido[2,3-d]pyrimidine, followed

9 Silylated 4-aminopyrimidines 2 or 5 upon ribosylation wi

10 talyzed coupling of glycosyl phosphates with silylated acceptors is also discussed.

11 n can be used to fine-tune the reactivity of silylated/acetylated sugar building blocks.

12 Addition of a silylated acetylide to 11 in diethyl ether/trimethylamin

13 (5) to chiral ketocyclopentenes 6 to provide silylated adducts 9 or alcohol derivatives 10 and 11.

14 the gem-difluoroalkyl radical generated from silylated adducts 9 or alcohols 10 and 11 afforded gem-d

15 and regioselective formation of mono- or bis-silylated adducts from commercially available substrates

16 iety by phosphine provided the corresponding silylated alcohols in useful yields.

17 thesis of O/C-glycosides with free alcohols, silylated alcohols, and C-type nucleophile acceptors in

18 pidly at ambient temperature to afford the O-silylated aldol products in good to excellent yield, and

19 ated amines in up to 93% yield from internal silylated alkenes.

20 at it is the more substituted benzylidene or silylated alkylidenes that are involved in the catalytic

21 is identical to that of the CM reactions of silylated alkynes and alkenes.

22 oselective cross metathesis reaction between silylated alkynes and terminal alkenes.

23 Moreover, silylated alkynes are shown to participate well in hydro

24 rst examples of the sigma-bond metathesis of silylated alkynes with aromatic carboxylic acids on the

25 ion between tertiary aliphatic chlorides and silylated alkynes.

26 In contrast, silylated allenes favor the formation of propargylic cat

27 cationic intermediates from nonsilylated and silylated allenes is strongly supported by DFT calculati

28 Several C-silylated (allyldimethylsilyl) calixarenes (1, 14, and 1

29 Esters of three types of silylated alpha-amino acids have been prepared from appr

30 commercial silica nanoparticles (SN) via the silylated amine and glutaric dialdehyde links.

31 dride that subsequently reacts to yield an N-silylated amine and the borane catalyst.

32 ureate catalyst was used to prepare 18 gamma-silylated amines in up to 93% yield from internal silyla

33 The silylated amino acid (l)-(trimethylsilyl)alanine (TMSAla

34 n of diverse bis-silyl ketene acetals with a silylated aminomethyl ether, followed by hydrolytic work

35 The silylated and fluorinated products were obtained as sing

36 opanation of olefins with alpha-stannylated (silylated and germylated) alpha-diazoacetate derivatives

37 They were silylated and subjected to a Perkow reaction with ethyl

38 rostanes were prepared and purified by HPLC, silylated, and then analyzed by gas chromatography (GC)

39 roleum-derived arenes into the corresponding silylated aniline derivatives, by using a mixture of sod

40 nd asymmetrically substituted arenes to form silylated arenes and to regenerate 1.

41 Taxol C and paclitaxel were sequentially silylated at the 2', 7, and 1-hydroxyl groups with tert-

42 es an activated dinitrogen unit which can be silylated at the beta-nitrogen atom.

43 selectivity is seen, leading to a series of silylated benzocycloheptene derivatives with a fully sub

44 clization of 2-isocyanothioanisoles toward 2-silylated benzothiazole building blocks has been develop

45 lyzed hydroaminoalkylation of alkenes with N-silylated benzylamine substrates.

46 Our previously proposed, silylated beta-lactone intermediate that led to successf

47 r procedure was employed in the synthesis of silylated bicyclopentanes and a linear triquinane.

48 rbynes undergo C-C bond formation, releasing silylated C2O1 fragments and demonstrating that the mult

49 in DME gave a mixture of tetrakis- and tris-silylated calixarenes (6 and 7).

50 s C for 48 h to form an 8.1:1 mixture of the silylated carbocycle (S,S)-trans-1, 1-dicarbomethoxy-4-m

51 Silylated carbocycles generated from benzhydryldimethyls

52 The NMR study indicates that the silylated carbonyl compounds are resonance hybrids of ox

53 A series of silylated carboxonium ions, 2a-6a, were prepared as long

54 rnal nucleophiles in one pot to afford alpha-silylated carboxylic acids, their derivatives, or TBS-su

55 igands that were generated starting out from silylated chalcogenide sources.

56 onyl chloride, using a catalytic amount of a silylated cinchona alkaloid as a source of chirality.

57 However, the reaction with the bis-silylated cluster [Ge9{Si(TMS)3}2](2)(-) yields the nove

58 y) or isopropyl- ((i)Pr) groups and the tris-silylated cluster [Ge9{Si(TMS)3}3](-) yield the novel ne

59 Reactions of silylated clusters [Ge9{Si(TMS)3}3](-) or [Ge9{Si(TMS)3}

60 vity of the dialkylhalophosphines toward the silylated clusters is observed depending on the bulkines

61 ins with a rather random distribution of the silylated comonomer when m-DMSS is used, but to chains w

62 g a direct access to synthetically versatile silylated compounds.

63 Silylated cyclopentanes derived from HSiMe(2)OSiMe(3) we

64 Silylated cyclopentanes derived from HSiMe(2)OSiPh(2)t-B

65 (6)H(3)(CF(3))(2)] to form the corresponding silylated cyclopentanes in good yield with high diastere

66 transition-metal-catalyzed rearrangement of silylated cyclopropenes to the corresponding allenes is

67 iolanyl acetate donor for N-glycosylation of silylated cytosine derivatives, leading to cis-oxathiola

68 tion reaction between p-nitroanisole and a C-silylated derivative of N-methylpyrrolidinone.

69 laced within the silica framework by using a silylated derivative of the well-known tris(bipyridine)r

70 xes, [M (VI)O 3- n S n (bdt)] (2-) and their silylated derivatives [M (VI)O 2- n S n (OSiR 3)(bdt)] (

71 The HOM tracers were identified as silylated derivatives by gas chromatography-mass spectro

72 The I(T) retention indices of silylated derivatives of 449 substances registered in th

73 from coffee beans, by means of the volatile silylated derivatives of acrylamide (AA) and headspace s

74 diequatorial chair equilibrium in a range of silylated derivatives of trans-1,4- and trans-1,2-dihydr

75 Silylated derivatives retain carbon with the silicon and

76 ration of uracil and thymine by way of their silylated derivatives under catalysis with stannic chlor

77 luoro ethyl salicylate analogues and their O-silylated derivatives.

78 enough to pass through a gas chromatograph, silylated derivatization reactions are commonly used to

79 (sp(2)) cross-coupling reaction makes use of silylated diazenes as diazenyl anion equivalents, and ch

80 The isolation of more stable silylated diazenido analogues, Fe(NNSiR(3)), and also of

81 reactions of a series of silyloxydienes and silylated dienes with acyclic alpha,beta-unsaturated ket

82 valuable and does not require presynthesized silylated diols.

83 ed-(benzylated), or the classic super armed (silylated) donors.

84 mounts of the corresponding free amine and N-silylated enamine are present in equimolar ratio during

85 ly and electronically very different in situ silylated enantiopure Lewis acid organocatalysts: i.e.,

86 yed to show that the alcohol stereocenter of silylated, enantiopure secondary alcohols can transmit c

87 Their reactions with pi-nucleophiles 8(a-j) (silylated enol ethers and ketene acetals) were studied k

88 s similar to those of pyrroles, indoles, and silylated enol ethers and, therefore, should be suitable

89 are derived from S(N)2-like reactions of the silylated epoxide with the diene, in which stereospecifi

90 luoro-3-coumaranones via the corresponding O-silylated ethoxy ketals.

91 ults predict similar behavior for some other silylated formamidines and related compounds.

92 tautomerization and elaboration of R to give silylated furanonaphthols 4 bearing an aldehyde side cha

93 ethyl-1,4-hydroquinone diacetate (16) formed silylated fused bicyclic complexes in good yield.

94 single trifluoromethyl fluorine atom with a silylated hemiaminal functional group.

95 on of tert-butoxide from silicon lead to the silylated heteroarene product.

96 terocycles enables the synthesis of valuable silylated heteroarenes.

97 sative cyclization of sp(3) C-O bonds in per-silylated hexitols is investigated by computation.

98 trichloride mediated cyclization reaction of silylated homoallylic alcohols, thiols, or amines with a

99 diiodide along with the N,N'-dicarboxylated silylated hydrazine.

100 ions of silylated hydroperoxyacetals furnish silylated hydroperoxides, which can be deprotected to ho

101 Lewis acid-promoted reactions of silylated hydroperoxyacetals furnish silylated hydropero

102 Ex) reaction between aryl fluorosulfates and silylated hydroxy groups.

103 ng salt metathesis reactions to alkylated or silylated imidazolinium derivatives, (L(E))ScR(3) (E = S

104 A novel silylated imine was designed to act efficiently in a che

105 o activate with precious metal catalysts are silylated in good yield and with excellent regioselectiv

106 but a (hydroxymethyl)boronic ester has been silylated in the usual manner.

107 Free hydroxyl groups were subsequently silylated in-port.

108 expedient synthetic strategy, the diverse C7-silylated indoles are synthesized effectively which exhi

109 The obtained silylated indoles have been employed in various transfor

110 s oxygen analogue have been synthesized from silylated internal alkyne using Larock's heteroannulatio

111 iminium ions with C-nucleophiles (enamines, silylated ketene acetals, and enol ethers) have been det

112 A silylated ligand that binds lanthanides condenses to for

113 d conditions by employing ring expansions of silylated methyleneaziridines.

114 The silylated methyloxonium ions are stronger electrophiles

115 One of these silylated N(2) species can be protonated or methylated,

116 Alkylation of O-silylated N-alkylmalonylhydroxamic acids provides a meth

117 n pyran- and furan-based donors with various silylated N-heterocycles.

118 Here, we assessed the ability of these new silylated NT compounds to bind to NTS1 and NTS2 receptor

119 al and theoretical study that elucidates why silylated nucleobase additions to acyclic alpha-alkoxyth

120 In the presence of an in situ silylated nucleobase, thioglycosides can be activated wi

121 ained diastereoselectively from additions of silylated nucleobases onto acyclic polyalkoxyaldehydes i

122 The addition of silylated nucleobases onto model C2-fluorinated dithioac

123 Likewise, silylated nucleophiles such as trimethylsilylazide, ally

124 zed to enhance the reaction scope and enable silylated nucleophiles to be efficiently exploited to sy

125 ow peroxycarbenium species can be trapped by silylated nucleophiles with high enantioselectivities an

126 ere successfully functionalized with various silylated nucleophiles without epimerization of the ster

127 honate approach involves a key intermediate, silylated nucleoside amino acid phosphoramidite 6, prepa

128 We report herein a 5'-silylated nucleoside scaffold derived from 3'-azidothymi

129 Its X-ray crystal structure reveals three silylated O(yl) ligands, confirming the unprecedented co

130 vide evidence for catalysis by boron and not silylated oxonium ions, though Si-F bond formation is th

131 a a novel three-step procedure starting from silylated polystyrene is reported.

132 rocarboxylic acid (HMDS and PFCA), the fully silylated PPAAs offer several advantages.

133 ive deprotection/oxidation of the respective silylated precursors with boron fluoride and subsequent

134 urinary matrix by solid-phase extraction and silylated prior to quantification.

135 as also accomplished by carbonylation of the silylated product, yielding an unprecedented mu-formamid

136 omofuran, and 2-bromopyridine failed to give silylated product.

137 e addition of 1,3-propane dithiol to various silylated propargylic aldehydes and ketones allows for a

138 The acetate 7 was condensed with silylated purine and pyrimidine bases, which produced th

139 Chiral silylated pyrrolidine catalysts are obtained in high yie

140 A Wittig reaction on a per-O-silylated rather than per-O-acetylated or -benzylated su

141 )H generation can be bypassed by using the O-silylated salicylate, and how the very slow liberation o

142 tion of indenyl substituent and demonstrates silylated sandwiches favor THF coordination and the eta(

143 t attachment of photoactivatable biotin onto silylated silicon wafers.

144 hroline; Ar = 3,5-C(6)H(3)(CF(3))(2)] formed silylated spirocycles in high yield with excellent regio

145 ric allylic alkylation performed on an alpha-silylated substrate, to ultimately permit access to an e

146 or some monosilyloxycyclohexanes and in some silylated sugars.

147 In a similar way, N-alkylated and N-silylated tert-butyl carbamates were used for the synthe

148 mediate along the proposed reaction pathway, silylated thiazolium carbinols have been identified to p

149 In this reaction, quinolones are silylated to form a quinolinium ion which then undergoes

150 In this process, chromones are silylated to form silyloxybenzopyrylium ions that lead t

151 l-phase HPLC separation, the isotopomers are silylated to their tBDMS derivatives.

152 N(2) must be silylated twice at the distal N atom before aryl migrati

153 ains with tapered block structures, with the silylated units near the initiator, when p-DMSS is used.

154 oxathiolane and dioxolane intermediates with silylated uracil analogues using TMSI as the coupling ag

155 o-2-deoxy-2-fluoro sugars with corresponding silylated uracil derivatives.

156 acetate 8 with the appropriate heterocycles (silylated uracil, thymine, N4-benzoylcytosine, N4-benzoy

157 Switching on uranium(V) reactivity: The silylated uranium(V) dioxo complex [(Me(3)SiOUO)(2)(L)(2

158 Aryllithium species were silylated using 1.5 equiv of tetraethyl- or tetramethyl

159 ethod was developed whereby morphine was bis-silylated using normal conditions followed by selective

160 cohols bearing a Z-iodoalkenyl tether can be silylated with chlorodimethylvinylsilane and subjected t

161 poly(ethylene-co-vinyl alcohol) (PEOH), was silylated with trimethylsilyl (TMS) groups followed by c