ライフサイエンスコーパス: simple

1 Our proposal is simple.

2 those genes with respect to FQ resistance is simple.

3 After a simple 1:1 dilution of plasma and whole blood, a quantit

4 It also implements a simple 2-node Bayesian network.

5 For the simple 2-phenoxy-1-phenylethane or its alcohol congener,

6 Development of this reaction would allow simple access to a vast range of difluoromethyl derivati

7 ted into mature capsid-like particles by the simple addition of viral protease, suggesting that it is

8 In this study, we discovered glycine as a simple additive for TFA mobile phases, which mitigates i

9 We illustrate our approach using a simple agent-based model of bacterial chemotaxis.

10 By focusing on pragmatic interventions and simple aims, we demonstrate the feasibility, acceptabili

11 Beyond simple alkali metals and ammonium, chemically diverse ca

12 roup was also alkylated and arylated through simple alkylation and Chan-Lam reaction, respectively.

13 generate complex, bioactive metabolites from simple amino acids.

14 development of intuitive local pictures and simple analytic theory.

15 ination for processing kinetic data sets, no simple and automated program existed for rapid analysis

16 -dimensional class-imbalanced data, which is simple and can be an alternative for performing feature

17 ploy basic features to train the models in a simple and coarse-grained manner.

18 The reaction can use both simple and complex starting materials to produce a range

19 We leverage this to train a simple and easily interpretable predictive model that ou

20 In addition to being a simple and effective route to a broad range of rotaxanes

21 Here, a simple and effective top-down approach is designed for p

22 In this manuscript, a simple and efficient sulfa-Michael addition reaction of

23 The proposed model is algorithmically simple and encompasses the Kalman filter as a special ca

24 The simple and fast protocol involves for the first time the

25 This method is simple and general, and the amount and polarity of charg

26 However, there are no simple and generalizable genetic methods to study neuron

27 ACBP is a topologically simple and highly conserved four-alpha-helix bundle prot

28 Here, we report a simple and inexpensive method to improve the efficacy of

29 ppropriate optical setup, opening the way to simple and inexpensive point-of-care assays.

30 ce, LSGEs could be an excellent platform for simple and low-cost electrochemical biosensor applicatio

31 In this paper, we demonstrate a simple and novel method to fabricate low-cost THz micros

32 The RAIL approach offers a simple and novel strategy for site-selective labeling an

33 This work reports a simple and powerful strategy to identify HCPs in antibod

34 In this work, we develop a simple and practical NMR method for extracting both ener

35 e overcome these challenges by introducing a simple and practical technique named multifactorial peak

36 The VP2-ELISA is universal and simple and provided sensitive (99%) and specific (93%) d

37 otent maturation-enhancing ECMs through this simple and rapid assay.

38 sis of 1,4-dihydroquinoline derivatives from simple and readily accessible substrates.

39 lthy volunteers but not quantitated with the simple and readily available amylase measurements employ

40 Here, we present a simple and robust CRISPR-Cas12a-based approach for combi

41 We recently developed a simple and robust microfluidic platform, DropMap, to mea

42 A simple and sensitive voltammetric method using edge plan

43 ety of functional groups and thus provides a simple and step-efficient method for pyrroloquinazolinon

44 Laser writing as a simple and straightforward method for covalent 2D patter

45 The proposed Fibonacci fibers are simple and straightforward to fabricate and have a rich

46 lculated with a two-b-value acquisition is a simple and sufficient diffusion-weighted MRI metric to a

47 While many simple and versatile ionization sources have been develo

48 The reaction is rapid, operationally simple, and chemoselective.

49 tiveness of beauty colored coverage, and the simple, and non-tousled application.

50 However, cells themselves are far from simple, and often take on complex shapes with a remarkab

51 r all future studies evaluating treatment of simple appendicitis in children, to reduce heterogeneity

52 rly those altering CTCF sites and provides a simple approach for functionally annotating the regulato

53 r RACD-level factors were considered but the simple approach of restricting RACD to a 200-m radius ma

54 The simple approach of thermal noise tracking points out new

55 In this study, we propose a simple approach to use network edges as features, based

56 On the basis of these results, we devise a simple approach, called UVHis-PAGE, that uses metal ion-

57 ation rate to the selection coefficient, the simple approximation can be substantially inaccurate.

58 gs (Rqc2 and NEMF), despite their relatively simple architecture, synthesize such C-terminal tails in

59 Such systems readily obtained from simple aromatic compounds could open up a multitude of s

60 ecular fragment should not be perceived as a simple aromatic isostere but rather as a readily interac

61 m designed fluorometer, enabling compact and simple ASFV detection, intended for low resource setting

62 cfDNA, measured by a rapid simple assay, proved a valuable early marker of severity

63 cancer, oncologic imaging has evolved from a simple assessment of tumor location and size to sophisti

64 g CNMs for water purification and opens up a simple avenue to creating 2D membranes through molecular

65 r high-temperature Li metal batteries with a simple battery configuration and high safety, which is d

66 nsing is needed to understand even seemingly simple behaviors.SIGNIFICANCE STATEMENT Motor-guided sen

67 diverse C-H activation/[4+2] annulations of simple benzoic acids are reported.

68 e metal oxide semiconductor electronics with simple binary compositions.

69 We propose a simple binomial probability metric to ascertain translat

70 Together, our results show how a simple biophysical mechanism in single neurons can gener

71 lopment, we tend to think of cells as small, simple, building blocks, such that complex patterns or s

72 liposomal bupivacaine, 55 patients received simple bupivacaine and 52 received placebo.

73 Here, we report a simple but effective enrichment and separation strategy

74 The results demonstrated a simple but efficient misannotation detection approach th

75 A simple but efficient one-pot or sequential copper-cataly

76 This study provides a simple but powerful framework for advancing SI in mainst

77 crosslinking data reinforces the notion that simple C-patch preference is not fully predictive of hnR

78 In this study, we developed a rapid and simple capillary electrophoresis-ultraviolet absorption

79 Sciaenid swim bladders vary from simple carrot-shaped to two-chambered to possessing vari

80 We show that simple chemical heuristics can be a powerful tool to cha

81 The use of simple chiral amines and easily prepared achiral or race

82 strategy employs automated and operationally simple chromatographic separation that is demonstrated t

83 tic biology, genetic elements, combined into simple circuits, are used to control individual cellular

84 In the second wave of synthetic biology, the simple circuits, combined into complex circuits, form sy

85 d pai-systems-was selected as a conceptually simple class of intrinsically porous nanocarbons to serv

86 immune responses against GBS compared to the simple co-administration of GBS67, CpGODN and liposomes.

87 d a pool of Persian speaking subjects with a simple color matching task under two conditions: percept

88 oncentrations (MIC) were then determined via simple colorimetric reactions in only 4.5-6 h using only

89 The use of a simple, commercially available ligand, PAd(3), is key to

90 Moreover, as the equipment needed is simple, common, and inexpensive, our test has immense po

91 more likely to survive exploitation than are simple communities.

92 We then applied our method to a simple computational model of microtubule dynamic instab

93 paradigms effective in inducing anxiety in a simple, consistent and sustained manner.

94 cial networks have often been considered as 'simple contagions'.

95 In this study, we examined a simple cost-effective approach for selective bromide rem

96 arly imprinted polymers (MIP), selective for simple coumarins, were used in three forms, as sorbents

97 ntly demonstrated the catalytic potential of simple, de novo-designed heme proteins.

98 ecies during gentle protein denaturation and simple density functional theory calculations of flavin

99 or to conducting the research, considering a simple descriptive method appropriate to answering real-

100 Moreover, the electron affinity is used as a simple descriptor to make a prediction on whether a give

101 A simple descriptor, mu/t, where mu and t are the octahedr

102 Despite its simple design and nonstringent assay condition requireme

103 Our results uncover a simple design principle of organ growth where progenitor

104 in series or parallel (and in any order) on simple devices.

105 uch steeper concentration profiles than does simple diffusion, which may facilitate neutrophil chemot

106 Using a simple donation game, which is a real-world version of t

107 Simple Doppler measurements gave a similar level of diag

108 verall transcriptome size does not exhibit a simple doubling in response to genome doubling, and indi

109 This simple, easy-to-use risk score calculator for patients a

110 BTSIXO) conjugated with Fe(3+)-ions via very simple eco- friendly synthetic protocol.

111 pproximation of MTV in 105 (76%) scans, with simple editing for a satisfactory result in additionally

112 that pedagogical questions are a relatively simple educational manipulation to improve memory, learn

113 A simple electrochemical method employing a novel semi-cir

114 chloride ionization and thereby circumvents simple elimination pathways.

115 nsistent with the reported phenomenology and simple enough to be inferred from upcoming experiments.

116 Here, we developed a simple enzyme-linked immunosorbent assay (ELISA)-based a

117 In this paper, we provide an elegant yet simple equivalent circuit model that captures the comple

118 nity context influence dispersal dynamics in simple experimental landscapes composed of homogeneous h

119 omponents of charantin namely STG and BSG by simple extraction technique followed by preparative HPLC

120 electronic devices combine high-performance, simple fabrication and distinctive form factors.

121 erefore, the proposed methodology provides a simple, fast, inexpensive, promising analytical tool for

122 selectively deliver high-value products from simple feedstocks such as olefins.

123 rapidly leveraging molecular complexity from simple feedstocks.

124 oderate to excellent yields (36-99%) after a simple filtration on a pad of silica gel.

125 le laboratory equipment such as a heater and simple fluorescent microscope.

126 A simple fluorine substitution to phenethylammonium for th

127 sensing proteins have only been tested using simple force protocols, such as constant or ramped force

128 interfacial and polarization effects in this simple form.

129 Bayesian decision theory provides a simple formal elucidation of some of the ways that repre

130 We provide a simple formula relating AIS geometry and sodium conducta

131 y conceptualise the response as a relatively simple function of a single environmental cues (e.g. a l

132 mplex molecular structures and functions via simple genetic mechanisms that recruit existing biophysi

133 ly involve breakage-fusion-bridge cycles and simple genome rearrangements rather than chromothripsis.

134 ificantly worse than an appropriately chosen simple gravity model.

135 hy some species have not transitioned beyond simple groups while others have taken the pathway to inc

136 the dynamics of cell growth and adherence to simple growth laws.

137 ore species and higher total abundances than simple habitats.

138 Furthermore, our approach relies on simple hardware implementations using off-the-shelf comp

139 In summary, we present a technically simple high-speed method for measuring contractile force

140 These results suggest that simple hydrogels, already built into numerous systems, h

141 ever, colloids in water defy the intuitively simple idea of forming crystals from oppositely charged

142 Herein, we suggest a simple in situ method to control the residual lithium ch

143 implementation of the GOAL questionnaire, a simple instrument with only four parameters easily obtai

144 lead to additional insertion products beyond simple integration of the donor.

145 The programming software allows for a simple interface to create fraction collection programs

146 sample.The application provides users with a simple interface to upload an input file in BED format a

147 Simple interventions such as swallowing assessments, bow

148 of late-life depression and targets it with simple interventions, co-designed with community therapi

149 to transient imines through the action of a simple ketone oxidant, followed by alkylation with a bet

150 Here, we show the first simple large-scale synthesis of free-standing Bismuthene

151 inear-to-branched (L:B) regioselectivity for simple linear alkenes.

152 using structural or functional brain scans, simple linear models perform on par with more complex, h

153 of variance, Pearson's chi-square test, and simple linear regression.

154 We report on the development of a simple, linear optical cavity-based system combining eva

155 circuits pushed far out of equilibrium by a simple low-dimensional suppressive drive might ameliorat

156 es of model development and assessment using simple, low-dimensional artificial stimuli.

157 In this work, using a simple macroscopic, fiber-optic resonator where the nonr

158 co-express, co-localize, and be explained by simple mass action kinetics, and more likely to contain

159 As predicted by a simple mathematical model, increasing sigma(B) expressio

160 Simple measurement of sewage properties and catchment po

161 We thus establish a simple mechanism for femtosecond spatiotemporal current

162 This simple mechanism generates permanent opinion polarizatio

163 ] with MOtBu (M = Na, Li) does not result in simple metathetic ligand exchange but entails disproport

164 In this work, a simple method allowing the quantification of the adsorpt

165 Here we developed a simple method based on spontaneous preference of zebrafi

166 rrelates strongly to the T(g), and that this simple method predicts the T(g) with a root-mean-square

167 A simple method to calculate the weighted mobility from Se

168 Here, we develop a simple method to test an alternative null hypothesis: th

169 need, here, we aimed to develop a novel and simple method without organic solvent extractions for th

170 Here, we designed a simple microbial community with three strains of E. coli

171 Overall, spray-capillary is a simple microsampling device that holds great potential f

172 environment, when compared with Lys-SNAs and simple mixtures of oxidized lysates with CpG-1826.

173 A simple model involving the biocatalytic reaction network

174 Making May's simple model more realistic is therefore unlikely to ent

175 n rate-limiting threshold and a conceptually simple model of CD8(+) T cell Ag recognition, in which A

176 Here, we build a simple model of sexual reproduction and create a theoret

177 We found that a simple model of spatial avoidance, together with attract

178 While SFG studies were initially limited to simple model peptides, the past decade has seen a dramat

179 These simple model systems not only establish a set of general

180 Using a simple model we show that the changes in growth are driv

181 mulation reveal rich phase behavior for this simple model, featuring a broken-symmetry striped phase

182 year mortality in each condition, developing simple models (and a tool for calculation) of excess COV

183 This simple modification can dramatically affect the activiti

184 tly, the presented results are achieved by a simple modification of photonic sensing chips which are

185 d as a single ionic white light emitter by a simple modification of the coordination environment.

186 vantages over conventional approaches, since simple modifications can be applied to recover a biopoly

187 ge patterns and combining these designs with simple modifications such as 2'-OMe to the DNA gap resul

188 amphiphilic Janus glycodendrimers containing simple mono- and disaccharides that mimic glycolipids ar

189 We hypothesize that unicellular and simple multicellular ancestors of green seaweeds survive

190 ferent interactions of their sample, perform simple network analyses, while also offering visualizati

191 roof of concept model showing that a single, simple network effect of noradrenaline on olfactory bulb

192 ecision tree, 0.96 by random forest, 0.91 by simple neural network, and 0.95 by XGBoost.

193 of the nematode Caenorhabditis elegans is a simple neuromuscular organ with a self-contained, autono

194 ncreased cellular complexity of traditional (simple) neuronal cultures by co-culturing with astrocyte

195 The inexpensive and simple NiBr(2)/1,10-phenanthroline system-catalyzed synt

196 udy is focusing mainly on the development of simple, novel, and cost-effective optical sensor to dete

197 ication note, we fill this gap by presenting Simple OLGA & SONIA (SOS), a web-based interface where u

198 rresponding compounds in high yields using a simple one-pot procedure.

199 generally rely on a single motor to perform simple operations and thus do not fully utilize the pote

200 digital quantification of cell viability by simple optical imaging using "single cell adhesion dot a

201 Combined with simple optical or electrical feedback, the structure is

202 indeed the motivations of behaviour, not so simple or straightforward to interpret.

203 irth most recently presented with continuous simple partial seizures and occasional breakthrough comp

204 hese two reaction pathways using bases and a simple Pd-based catalyst system to promote a para-select

205 ucture-function characterization, we present simple peptides that bind alpha-cobratoxin (alpha-Cbtx)

206 disorder (ASD) show enhanced performance in simple perceptual discrimination tasks.

207 These findings imply a simple phenotypic model of TCR signaling in which multip

208 pressurization was qualitatively mimicked by simple physical models of muscle morphology that display

209 nature of condensates could complicate this simple picture.

210 oxidatively transposed cyclopentenones from simple PKR products.

211 Here, we describe a simple platform for the expansion of functional mouse HS

212 ources of data were more discriminative than simple PLS1-DA, yielding better prediction for Chetoui a

213 oped test strip shows promise as a rapid and simple POC quantitative acetaminophen assay.

214 Furthermore, the simple polarity control strategy is extended for realizi

215 A simple, portable and cost-effective device was also util

216 We present a simple power-law model for the frequency of repeat synth

217 truction of complex molecular scaffolds from simple precursors, has been a long-standing challenge in

218 cuss the simulation results in relation to a simple probabilistic framework that captures the power l

219 The method offers an attractive and simple procedure using commonly available shelf reagents

220 onto muscovite mica is demonstrated using a simple procedure.

221 resentational spaces these methods generate, simple prototype models can perform comparably to the mo

222 The rapid and simple quantification of sodium by the TT-IR and TIE sho

223 ently, techniques for the fast, specific and simple quantitation of microRNAs are becoming crucial en

224 Increasing clinical awareness and access to simple rapid diagnostics may improve the diagnosis of bl

225 nd smartphone-based color analysis, enabling simple, rapid and reliable nucleic acid quantification w

226 rent genomic HPV genotyping algorithms use a simple read-alignment and filtering strategy that has di

227 re primarily public clones, characterized by simple rearrangements of Vgamma9 and Vdelta2 chains with

228 ventricular function may be best served with simple reassurance.

229 With the aid of a simple reductive quenching photoredox cycle, we have suc

230 One is model-free learning, i.e., simple reinforcement of rewarded actions, and the other

231 The most common bidentate phosphines are simple, relatively inexpensive ligands, such as DPPE, DC

232 We present a simple, remote sulfonation solution to BODIPY photocages

233 However, the simple removal of fucosyl residues, which results in red

234 during dedifferentiation was predominantly a simple reversal of developmental changes, with expressio

235 A simple risk factor and CACS-CL tool enables improved pre

236 After 5 years, the simple rule of 5 identified 37.5% of eyes as progressing

237 In this article, I outline Ten Simple Rules to follow when writing an algorithmic bioin

238 The method employs a simple ruthenium catalyst, does not require external lig

239 The approach is conceptually simple, scalable, and can be applicable to a wide range

240 many elements of the interactions of S1 with simple secondary structures are known, mechanistic detai

241 between Landau levels (LLs) are described by simple selection rules associated with the LL index N.

242 In this paper, a simple, sensitive and precise electroanalytical method w

243 Our results demonstrate that simple sequence motifs can rigidify elementary membrane

244 l bins 2.02, 2.05-2.06, and 6.05 between the simple sequence repeat (SSR) markers umc1165-bnlg1017, u

245 tential sources of molecular markers such as simple sequence repeats, large repeat sequences, and sin

246 Recognition of simple shapes and numerosity estimation for small quanti

247 fusion, the fluorescence recovery produced a simple single-exponential decay in the spatial Fourier d

248 This simple "sizer-oscillator" arrangement reproduces the exp

249 Initiated by a simple slipping step, the aqueous solution can robustly

250 (~5.1 eV), which are achieved by combining a simple solution processing with modulation of surface co

251 Here we use a simple, sorghum system with abundant sampling to show th

252 cortical changes in alpha power not only for simple spatial and feature attention, but also for high-

253 Optogenetically suppressing Purkinje simple spikes, while preserving complex spikes, suggeste

254 The method proceeds from very simple starting materials such as 1,2-diamines and alkyl

255 accessing structurally complex products from simple starting materials.

256 FLD) encompasses a range of conditions, from simple steatosis to nonalcoholic steatohepatitis.

257 from relatively simple tasks and relatively simple stimuli.

258 In this paper, we show that this simple strategy applied to weekly data of the Keeling cu

259 Reported here is the development of a simple strategy for deoxyfluorination, using first-row t

260 This work highlights a simple strategy for polyMOF membrane formation and pushe

261 noARVs as an effective, safe yet technically simple strategy to enhance brain delivery of darunavir a

262 uids have on intermediate and large scales a simple structural order given by alternating layers with

263 lency molecules because of its compact size, simple structure, and natural propensity to tetramerize.

264 ermal etching (SATE) of gallium nitride is a simple subtractive process for creating novel device arc

265 to ionize an extended range of chemicals by simple switching between DESI, voltage-free EASI, or LTP

266 In this work, we propose a simple synthetic route to obtain different vlasouliolide

267 oquinoline ring system is elaborated using a simple synthetic strategy.

268 in vitro, establishing a potential route to simple, synthetic, low-cost antivenoms.

269 ibiotics and splits bacterial samples upon a simple syringe injection step to initiate AST against al

270 ol of each motor element in this numerically simple system paves the way for future study of both ref

271 sing and performance derives from relatively simple tasks and relatively simple stimuli.

272 We propose a simple technique to monitor changes in hemolysis levels

273 signal sequence and expression vector, this simple technology can likely be used with many model org

274 Here, we develop a simple theoretical framework that allows measuring the r

275 We, therefore, present a simple thermal-oxidative compositional inversion (TOCI)

276 ensor provided highly reproducible data, was simple to fabricate at low cost, exhibited higher sensit

277 ows that thin-film-coated ITO electrodes are simple to make and can be useful electrode substrates fo

278 bility which can be reused up to 7 times, is simple to prepare and convenient to use for the extracti

279 We have designed a flexible, simple to setup viewer that is easily adaptable to any t

280 t biomass, konjac glucomannan, together with simple-to-fabricate iron-based metal-organic framework-d

281 We develop here an intuitive, powerful and simple-to-implement approach for mitigation of cascading

282 ms of rHuEPO and as such represent powerful, simple-to-use analytical tools to monitor the conformati

283 This simple-to-use model can be used to both analyze and desi

284 In conclusion, here we present a simple tool, extensible to Orbitrap-based mass spectrome

285 ge ferromagnetic spin systems, we identified simple topological counting rules to predict the relativ

286 We recently described FlyBox, a simple tracking system for assaying Drosophila locomotor

287 vanadium dioxide (VO(2) ) is the only known simple transition-metal oxide that demonstrates a near-r

288 arning and nucleus accumbens activation in a simple unidimensional reinforcement-learning task was no

289 e shared with colleagues or publishers via a simple URL.

290 AnnoGen is characterized with simple utility modes and succinct HTML report of informa

291 (i.e., considering multiple drivers), beyond simple vicariance of Caribbean and Pacific lineages, are

292 r visual areas are important for seeing even simple visual features, whereas other areas have more co

293 without any aids and then with the aid of a simple visual guide.

294 Simple visual stimuli were presented to adult individual

295 In the first step, a simple W(1)/O emulsion was prepared with distilled water

296 By enabling a simple way to control the surface functionality of metal

297 We used a simple whole-cell coarse-grained model of cell physiolog

298 Herein, we show a simple yet effective way to modulate the self-aggregatio

299 ver km in the western U.S., and then applied simple yet plausible future stream temperature change sc

300 Now, a simple yet robust acid-treatment strategy is used to jud