ライフサイエンスコーパス: simplify

1 me-consuming workflow has been significantly simplified.

2 hough a vast number of studies have aimed to simplify access to such materials through the C-H bond f

3 eural representations get transformed into a simplified action signal along a hypothalamic-midbrain p

4 s: 67%; mean +/- SD age: 59 +/- 16; and mean Simplified Acute Physiology Score 2: 54 +/- 20), 53 (54%

5 Median Simplified Acute Physiology Score II and Sequential Orga

6 Severity of illness was measured using Simplified Acute Physiology Score II and Sequential Orga

7 After adjustment to Simplified Acute Physiology Score II and Sequential Orga

8 66.6 pg/mL (34.6-136.4 pg/mL) and the median Simplified Acute Physiology Score II score 49 (36-63).

9 abetes mellitus, and higher severity scores (Simplified Acute Physiology Score II).

10 n-hospital death exceeding 15% (based on the Simplified Acute Physiology Score II).

11 After adjustment for the Simplified Acute Physiology Score II, in-ICU death was p

12 , 1.85; 1.49-2.29) and, after adjustment for Simplified Acute Physiology Score II, with mortality (od

13 these naturally occurring substitutions in a simplified AgRP scaffold.

14 Building on the Simplified Algorithm for Treatment Eligibility (SLATE) I

15 We developed a novel, simplified alternative method for quantifying valve func

16 -ribosome structure enabled the synthesis of simplified analogues that retained both potency and sele

17 We addressed this data gap and dramatically simplified and accelerated RNA ensemble determination by

18 proaches to making PrEP services accessible, simplified and efficient.

19 nutes and the well-based platform provides a simplified and familiar testing interface that can be re

20 A simplified and inexpensive prepurification method was al

21 y to reach its maximum potential, it must be simplified and more widely disseminated.

22 This new strategy simplifies and enhances the process of probe optimizatio

23 sources, this unified framework considerably simplifies and extends the modeling scope for granular d

24 SIMPLIFY and D3FEAT are international, multicenter studi

25 SIMPLIFY and D3FEAT are phase 4 trials evaluating the ef

26 By providing methods to simplify and potentially automate radiation dosimetry, w

27 IVF procedures, as well as to significantly simplify and radically change other cell analyses and te

28 demonstrating the power of the algorithm to simplify and to help understand highly complex reactions

29 Many tasks carried out by hand will need simplifying and automating.

30 his work has significant implications toward simplifying and improving CBC and blood smear analysis,

31 proposed methodology with two case studies, simplified apoptosis and lipopolysaccharide-induced NFka

32 We demonstrate the command line tool's simplified Application Programming Interface on two impo

33 A simplified approach to monitoring for QT prolongation an

34 sses) analyses and to develop and evaluate a simplified approach, standardised uptake value ratio (SU

35 he discovery of a very potent but profoundly simplified archazolid analogue.

36 We aimed to establish whether simplified ART initiation with the offer of same-day tre

37 As expected, a simplified artificial mimic of cigarette smoke odor test

38 Unlike simplified, artificial stimuli, real-world scenes contai

39 al role in decision-making models, are often simplified as a single pool of non-selective neurons lac

40 d of modeling time-dependent inhibition that simplifies assay setup and allows comparison of inhibiti

41 3-based detection to occur in a single step, simplifying assay preparation and reducing run-time.

42 This platform potentially improves and simplifies assessment of biased agonism because the same

43 from biosensors instruments is based on the simplified assumption that also larger biomolecules inte

44 However, current methods typically make the simplifying assumption that cells are straight rods.

45 Thoughtful use of simplifying assumptions is crucial to make systems biolo

46 in networks of coupled oscillators ground on simplifying assumptions, which often neglect key biologi

47 developed in MBITES under a specific set of simplifying assumptions.

48 trix X is known and is computed based on the simplifying assumptions.

49 ssues with data quality and biases caused by simplifying assumptions.

50 del of a complex system, our model relies on simplifying assumptions: For example, we simplified path

51 With facile cell fabrication, simplified battery structures, high safety, and low main

52 We show that this simplified behavioural decision approach predicts most a

53 t-on-a-chip captured essential features of a simplified bile duct in structure and organ-level functi

54 degradation, allowing long-term, storage and simplifying biochemical analysis.

55 vely evaluate the drug distribution within a simplified biphasic (emulsion) system.

56 assisted modeling approach that dramatically simplifies both offline and online 2D-LC method developm

57 Simplified brain dynamics were simulated using a compute

58 Barcoding has been considerably simplified by developments in high throughput sequencing

59 One possibility is that neural control is simplified by limiting the space of hand movements.

60 flexible meaning emerges in language can be simplified by studying adjective-noun phrases.

61 ling results, the interpretation of which is simplified by the absence of a different counter-electro

62 e methods is demonstrated and discussed in a simplified case study.

63 gated using computed interaction energies of simplified catalyst and substrate structures, providing

64 In addition to being used as simplified cell models to decipher the rules of life, ar

65 nd verification of its clustering result and simplifies cell-type annotation with domain knowledge in

66 wer-visiting insects, we need to move beyond simplified choice sets towards a view of multi-attribute

67 nificantly improved immunoglobulin recovery, simplified chromatography, and high throughput (HT) data

68 nstrumentation should help to streamline and simplify clinical proteomics studies.

69 the cPRA per titer is a reliable approach to simplify complex antibody data and an ideal endpoint for

70 ometry has grown into a powerful approach to simplify complex mixtures, disentangle isomers, and eluc

71 n tongue as a porous material to drastically simplify computational approaches and that peripheral tr

72 acement for tuberculin skin testing (TST) to simplify contact evaluation and improve implementation.

73 OF ASYMMETRY IN THE STOMATAL LINEAGE) in the simplifying context of cultured cell filaments and in pr

74 reatment eligibility and the accuracy of its simplified criteria have been poorly documented in patie

75 icipants with recent IDU (previous 6 months; SIMPLIFY, D3FEAT) or current OAT (D3FEAT) between March

76 xity, allows for shorter analysis times, and simplifies data evaluation.

77 ingle peptide oxidation isomer peak, greatly simplifying data acquisition and data analysis.

78 with asymptomatic volunteers (n = 28), while simplified dbRT-RPA showed 89% accuracy.

79 This simplified decomposition allows us to devise a fast Mont

80 bility, however, more compact versions would simplify delivery and extend application.

81 el HIV reductions, highlighting the need for simplifying delivery and reducing current barriers to ac

82 n male mice results in DG granule cells with simplified dendritic arbors, reduced dendritic spine den

83 Here, we report a simplified design of the calcium and light dual integrat

84 nt and low-loss optical devices and enabling simplified device integration.

85 cate that 16S V1-V2 metagenomics can greatly simplify diagnosis and accelerate the discovery of bacte

86 solutions to urgent clinical needs including simplified diagnostic technologies suitable for use in t

87 Simplified diagnostics are required for low-resource set

88 ds: In this work, a technical description of simplified dose estimation is presented and applied to t

89 ts enrolled in the ODYSSEY-trial to evaluate simplified dosing in children with HIV.

90 phate prodrugs provide them the potential to simplify drug dosage forms for PIB-containing HCV therap

91 otin-functionalized probes to cultured cells simplified enrichment and elution to enable the mass spe

92 A simplified ERP can uniformly be implemented across multi

93 A simplified ERP with seven key domains (minimally invasiv

94 initial benzofuran-amide scaffold yielded a simplified ether series of inhibitors, utilizing acyclic

95 o remove the need for pre-enumeration and to simplify field logistics for the population healthcare u

96 SICM measurements, fitted to a simplified finite element method (FEM) model, revealed s

97 We applied a simplified flow cytometric assay to identify patients wi

98 We distinguish between these hypotheses in a simplified form of contour integration, namely judging w

99 We conclude that as well as providing a simplified framework for model development, the S-System

100 We provide a simplified framework for the perimetrist to improve the

101 A universal SP test would simplify frontline diagnostics and facilitate large-scal

102 tensity sodium adducts and therefore greatly simplified glycan profiles.

103 binocular loupe and graded based on the WHO simplified grading system.

104 th system models represent soil moisture but simplify groundwater connections, a primary control on s

105 Simplified gyral pattern of the cortex and abnormal corp

106 sign of novel H&H-Pupil-Age score (HHPA) and simplified H&H-Pupil score (sHHP), respectively.

107 ber of existing analysis tools, thus greatly simplifying Hi-C matrix analysis.

108 ice were colonized as neonates with either a simplified human infant microbiota consortium consisting

109 Two simplifying hypotheses have been proposed for whole-plan

110 ns for improved personalized dosimetry using simplified imaging schemes.

111 We simplified immune indices into three principal component

112 ches have often ignored seasonality by using simplified intermediate-host modeling, or by restricting

113 This new method simplifies interpretation of liver stiffness results and

114 Our method, named FastSK, uses a simplified kernel formulation that decomposes the kernel

115 Congeners possessing the monodiene with a simplified lactone had superior anticancer efficacy rela

116 he success of our approach in explaining and simplifying landscape-level variation in climate change

117 By simplifying library preparation CUT&Tag requires less th

118 enumeration of households in sampling areas, simplified logistics and could be replicated in future c

119 entry format provides a greater flexibility, simplifies maintenance and allows the capture of more in

120 onsensus sequencing workflow (UMIC-seq) that simplifies mapping of evolutionary trajectories based on

121 From the simplified measures, SUV normalized for body weight at 5

122 the segregation of signaling molecules and a simplified mechanical model for actin cytoskeleton netwo

123 g common and exclusive traits, we signpost a simplified mechanism to address the problem of applicati

124 sthma transition recommendations include (a) simplifying medication regimes and using reminders; (b)

125 esults reveal that ephaptic coupling, in the simplified mesoscopic modeling approach used here, signi

126 several intuitive interfaces for a rapid and simplified method design.

127 At the end of this paper, a new simplified method was proposed to estimate specific stor

128 We use this approximation to define a simplified metric (EMOD1) that weights dipole coupling a

129 We consider a simplified model based on a stochastic growth process dr

130 vinylneoxanthobilirubic acid methyl ester, a simplified model of a bilirubin dipyrrinone subunit resp

131 We demonstrate that the simplified model of a constant restitution coefficient f

132 -inserting into a lipid bilayer, represent a simplified model of biological membrane channels.

133 Using a simplified model of the pore of the 5-HT(3) receptor (5H

134 Simplified model systems suggest that monomers are limit

135 Simplified model systems(3-6) have led to the concept th

136 This procedure provided a simplified model that still connects two monostable syst

137 and -450 mC m(-2) were found using the same simplified model.

138 tions with high air conditioning prevalence, simplified modeling approaches may adequately account fo

139 delays on net carbon assimilation have used simplified models of crop canopies, limiting the accurac

140 pplication domain, and in fact it applies to simplified models of ecological, neuronal, and traffic n

141 meter-size domains are routinely employed as simplified models of plasma membranes.

142 ased on quantum chemical calculations and on simplified models that allow for extrapolation to "infin

143 as proven to be difficult to establish using simplified models that are based on behaviour alone.

144 ly, nuclear interactions are described using simplified models, which are well constrained at typical

145 EasyVS is a web-based platform built to simplify molecule library selection and virtual screenin

146 o deaths related to the medications with the simplified monitoring approach and health care provider

147 amics, and although general assumptions that simplify motor ensembles result in global contractile be

148 SIMPLIFY, NCT02336139; D3FEAT, NCT02498015.

149 2 nm in proteins can largely be described by simplified nonadiabatic theory, it is not known how thes

150 1-pentanethiol is a critical component of a simplified odorant mixture designed to mimic cigarette s

151 d-liquid extractions, sample pretreatment to simplify off-chip analysis, and for portable spectroscop

152 To simplify on-site water sampling and screening, particula

153 cal analysis of this model, simulations of a simplified one-dimensional cell geometry, and two-dimens

154 ed by developing a kinetic theory based on a simplified one-dimensional model for OHCs.

155 By omitting the lipid extraction step, these simplified one-step methods offer a much higher throughp

156 ture beads and implement a more scalable and simplified optical decoding process.

157 articipants received sofosbuvir/velpatasvir (SIMPLIFY) or paritaprevir/ritonavir/dasabuvir/ombitasvir

158 received sofosbuvir/velpatasvir (once daily; SIMPLIFY) or paritaprevir/ritonavir/ombitasvir, dasabuvi

159 tionally characterize these human genes in a simplified organismal context.

160 ly incorporated in pipelines, and provides a simplified output suitable for direct usage in downstrea

161 , normalized for body weight, is an accurate simplified parameter for uptake assessment of baseline s

162 on simplifying assumptions: For example, we simplified pathways in the healthcare and criminal justi

163 DTG + FTC or to continuing cART, and 1:1 to simplified patient-centered monitoring versus standard m

164 t the results of this study will improve and simplify patient selection for COA intervention and pote

165 The largest source of savings was simplified payment administration (median 8.8%), and the

166 ed healthcare utilization and savings due to simplified payment administration, lower drug costs, and

167 Simplified personalized dosimetry in the clinic continue

168 MapGL simplifies phylogenetic inference of the evolutionary hi

169 A simplified PLSR model based on optimal wavelengths showe

170 file associated with a pipeline stage, JUDI simplifies plug-and-play of the pipeline stages.

171 kg or more, with no safety signal, allowing simplified practical dosing and rapid access to dolutegr

172 /min [23-31] vs. 29 [26-32]; P = 0.027), Pes-simplified pressure-time product (93 cm H(2)O . s . min(

173 Pes-simplified pressure-time product and transpulmonary pres

174 on, reduces dyspnea, inspiratory effort, and simplified pressure-time product, with similar transpulm

175 However, its application is still limited to simplified problems in two dimensional space or straight

176 ghly complex monodisperse dendrimers through simplified protocols.

177 MS has a great potential for simplifying quantitative analysis without the need for t

178 this classic model system under considerably simplified reaction conditions, adding to the current me

179 A stable coding scheme simplifies readout for WM-guided behaviour, whereas the

180 The simplified reference tissue model (SRTM) slightly undere

181 slightly underestimated 1TC BP (ND), and the simplified reference tissue model 2 (SRTM2) improved BP

182 placeable compartment, was derived using the simplified reference tissue model with cerebellum as ref

183 lthough the Hubbard model provides a greatly simplified representation of most real materials, it is

184 ed river flows and fragmented habitats often simplify riverine communities and favor non-native fishe

185 ithout the corrections, were compared, and a simplified rule-of-thumb (RoT) correction factor (CF) wa

186 e-pot, lyophilized, isothermal assays with a simplified sample preparation method independent of nucl

187 xicity, freeing up of fluorescence channels, simplified sample preparation, and the ability to re-pro

188 witch of the heme axial ligation within this simplified scaffold.

189 on-advanced AMD subjects (AREDS grade 1-4 on simplified scale) and 34 age-matched normals (AREDS grad

190 His IAIHG and simplified score was compatible with definite AIH and hi

191 both eyes, and Age-Related Eye Disease Study simplified score), (3) a summary genetic risk score base

192 CHANGE-seq is a simplified, sensitive and scalable approach to understan

193 tes the need for pre- or post-enrichment and simplifies single-cell workflows, making it useful for o

194 s, frogs have a highly derived body plan and simplified skull.

195 and the CRISPR toolbox, which could offer a simplified solution for site-directed display of small m

196 ated Gaussian heterojunction transistors for simplified spiking neuron implementation.

197 In this review we seek to simplify stomatal behaviour by using an evolutionary per

198 minimal amounts of blood, sample collection, simplified storage and shipping conditions at room tempe

199 Conclusion: Simplified STP dosimetry methods may compromise the accu

200 Simplified strategies to detect tumor cells (Sezary cell

201 e LAMPOON is an effective, reproducible, and simplified strategy to lacerate the anterior leaflet bef

202 apply molecular dynamics simulations using a simplified "structure-based" energetic model.

203 An alternative assumption is suggested for simplifying such pathways.

204 SimCells represent a simplified synthetic biology chassis that can be program

205 ocesses have the potential to streamline and simplify synthetic routes, they are currently limited by

206 The latter is not only a highly simplified system compared to previous microwell-based b

207 benefits of fiber-assisted AI-ETD, namely, a simplified system for irradiating the two-dimensional li

208 This simplified system thus reveals the dynamic formation and

209 ripts with S2 cleavage sites, we generated a simplified system to identify the new YME1L-dependent si

210 To simplify testing and reduce the volume of required reage

211 The application of chemometrics simplified the kinetic interpretations and hence the pre

212 Unlike traditional MSPD, we simplified the method without the use of mortar/pestle a

213 vergent coupling at the end of the synthesis simplified the route considerably.

214 uorescence decay analysis that substantially simplifies the acquisition and analysis of time-resolved

215 Our protocol simplifies the analysis and guides the initial interpret

216 h the omission of chromatographic separation simplifies the analytical process, extra procedures may

217 y expanding the encodable sequence space and simplifies the computational burden in designing sets of

218 tic circuit design automation for eukaryotes simplifies the construction of regulatory networks as pa

219 approach provides conservative estimates and simplifies the coupling of models as BCFs are slightly m

220 ve molecules, and so this synthetic approach simplifies the discovery of radioligands.

221 This greatly simplifies the experimental exploration of quantum codes

222 ificantly, this separation technique greatly simplifies the exploration of block copolymer phase spac

223 The use of BRET simultaneously simplifies the hardware required for sensing and offers

224 In particular, it simplifies the inclusion of new interactions, whilst als

225 This greatly simplifies the modeling and quantitative interpretation

226 tion, which improves the detection limit and simplifies the operation compared to linear ligation-RCA

227 TIR geometry with nanoinfrared microscopies simplifies the optical alignment, providing alternative

228 t even a moderate rung coupling dramatically simplifies the phase diagram below half-saturation magne

229 us, minimally basic" ("NAMB") technique that simplifies the process and avoids the basic conditions t

230 ther, this collection of libraries and tools simplifies the process of constructing realistic geometr

231 This simplifies the regulatory programs that guide neonatal H

232 This encapsulation methodology simplifies the screening of reaction conditions and the

233 Here we report a strategy that simplifies the synthesis of terpenes by inverting the or

234 gation to remove the need for wash steps and simplifies the system to a single reagent addition step.

235 cused on the development of a CRMS method to simplify the charge profile of the polymers and then cou

236 g the calculation of the laser beam waist to simplify the comparison and reproducibility of results.

237 Notably, DSSR can dramatically simplify the depiction of G-quadruplexes by automaticall

238 for applications including advanced tools to simplify the digital reconstruction and simulation of th

239 d approach will provide a versatile route to simplify the electronic skin systems with reduced archit

240 A central goal in microbial ecology is to simplify the extraordinary biodiversity that inhabits na

241 top protocol, this microfluidic platform can simplify the fabrication procedure and produce a large n

242 Besides, origami folding was employed to simplify the fabrication process further.

243 resents a new design that will significantly simplify the fabrication/operation and meanwhile boost t

244 ssing issues in the lipidomics field: (1) to simplify the implementation of lipid name handling for d

245 fic to branching residues was established to simplify the MS/MS data interpretation of closely relate

246 Our approach is to simplify the network by aggregating into groups the node

247 modified antegrade transseptal technique may simplify the procedure.

248 iding up regularisation and registration can simplify the process and provide flexibility.

249 We aimed to simplify the risk stratification after variceal bleeding

250 nterventions was introduced in an attempt to simplify the routine application of coronary physiology-

251 The other goal of this paper is to simplify the same system as much as possible without los

252 To simplify the scan protocol, SUV ratios (SUVRs) were comp

253 acon Calculus, a process algebra designed to simplify the task of modelling interacting biological co

254 In an attempt to simplify the teaching and dissemination of this field, w

255 Furthermore, to simplify the workup of COF materials, a simple nitrogen

256 AGENOTE is a public resource that focuses on simplifying the annotation and submission process of dat

257 These diagrams are useful for simplifying the biological process in question and disti

258 easily combined with other devices, greatly simplifying the construction and assay procedures.

259 ination with electrochromic materials, allow simplifying the construction of these devices, leading t

260 whole frequency range using a single model, simplifying the design of electronic systems of integrat

261 are obtained through the same waveguide thus simplifying the detection scheme and potentially enablin

262 mplification step (e.g., PCR) required, thus simplifying the operation further.

263 Simplifying the three-component system to two-component

264 By simplifying the workflow and shortening the development

265 t 100-fold slower than expectations based on simplified theory.

266 Long-acting injectable regimens may simplify therapy for patients with human immunodeficienc

267 One idea is that rules could simplify these computations.

268 across the middle membrane, and an extremely simplified TIC complex.

269 scarding physiologic uptake may considerably simplify TMTV estimation, reduce observer variability, a

270 atical analyses showed that the model can be simplified to a reversible two-state system and solved a

271 rinsic contact angle), the expression can be simplified to a single, dimensionless number that encaps

272 te regression methods that are often further simplified to allow transformation into a scoring formul

273 assessment of registered chemicals could be simplified to synthetic chemical classes or types and gr

274 Such approaches have been further simplified, to network-based models, and offer researche

275 ding health-care savings, and implementing a simplified treatment algorithm.

276 ed therapies are now available with markedly simplified treatment algorithms.

277 fication and FibroScan); and the accuracy of simplified treatment criteria free from HBV DNA and Fibr

278 Point-of-care testing can simplify treatment and improve outcomes for HIV-positive

279 udy (ComPAS) assessed the effectiveness of a simplified, unified SAM/MAM protocol for children aged 6

280 In addition, the accuracy of simplified uptake metrics such as SUV was investigated.

281 Simplified uptake parameters included tumor-to-blood rat

282 As a demonstration of how modeling can be simplified using our approach, we have included a comple

283 ss scale (H&H), pupil status and age or in a simplified variation only H&H and pupil status, leading

284 We also develop an algorithm for simplifying variation graphs for k-mer indexing without

285 Few studies have shown if a simplified version of ERP implemented across multiple su

286 A simplified version of the model was derived by assigning

287 tations within the network and also derive a simplified version of the model.

288 We apply the model and its simplified version to analyze micropipette aspiration co

289 in action, but the samples are often highly simplified versions of the complex native environment.

290 to the Wells Score and Geneva Score and the simplified versions of these two scores, calculated retr

291 arine environmental change and can provide a simplified view of plankton biodiversity, building an un

292 found pest outbreaks increased four-fold in simplified, vineyard-dominated landscapes compared to co

293 ey receive from their own self movement in a simplified virtual reality setup.

294 Sophisticated analysis and simplified visualization are crucial for understanding c

295 ntraepithelial lesions and suggests that the simplified WHO classification scheme is appropriate for

296 -B was significantly higher than that of the simplified WHO criteria (p<0.001).

297 Compared to the simplified WHO criteria free from HBV DNA quantification

298 rom HBV DNA and FibroScan (TREAT-B score and simplified WHO criteria) to select patients for antivira

299 The airspaces of Col6a1(-/-) lungs appeared simplified, with larger (29%; P < 0.01) and fewer (31%;

300 targeted next-generation sequencing include simplified workflow, reduced overall cost, and the poten